What are the cheapest airlines flying from Knoxville to Syracuse round-trip?

According to our current data, Delta ($249), American Airlines ($509), and United Airlines ($578) offers the cheapest pricing from Knoxville to Syracuse. You may be able to fly from Knoxville to Syracuse for 21% less than the average price by searching for these airlines.

What is the cheapest day to fly from Knoxville to Syracuse?

Travelers seeking maximum savings on their Knoxville to Syracuse flight should consider departing on Wednesday afternoons when fares are most often at their lowest. Sunday mornings flights should be avoided if possible as fares are typically the most expensive at this time.

What are the most popular airlines that fly from Knoxville to Syracuse?

Before booking your flight from Knoxville to Syracuse check out the most popular airlines for this route: American Airlines, Delta or United Airlines.

What is the cheapest day to fly round-trip from Knoxville to Syracuse?

It’s generally more expensive to depart on a Tuesday, if you have to leave on this day you can still search on Cheapflights to find great options that meet your needs.

What is the cheapest month to fly from Knoxville to Syracuse?

September can be a great time to fly to Syracuse from Knoxville with a flight ticket averaging about $319. Cheapflights users have found deals in the month of September for as cheap as $208. The most expensive prices can be found in the month of December.

Most accurate provider : When it comes to deals on Knoxville-Syracuse flights, users find the pricing of FlightHub to be most consistent on Cheapflights vs. FlightHub Users can find the same prices on Knoxville-Syracuse flight deals on Cheapflights vs. FlightHub >95% of the time. Price accuracy is based on data collected from Knoxville-Syracuse flight searches over the past month and is updated monthly.

Most trusted provider : When it comes to deals on Knoxville-Syracuse flights, Cheapflights users trust FlightHub the most. FlightHub has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Knoxville-Syracuse flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.

Can I find deals for flights from Knoxville to Syracuse that include hotel bookings?

Yes. In addition to deals on Knoxville to Syracuse flights, Cheapflights offers vacation packages that include both flights and hotel.

How can I find direct flights from Knoxville to Syracuse?

After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Knoxville to Syracuse.

Can I find deals for business class flights from Knoxville to Syracuse?

Yes. Cheapflights offers flight deals from Knoxville to Syracuse by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

$249+ Flights from Knoxville to Syracuse

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1. Tell us where you want to go

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Cheap flight deals from Knoxville to Syracuse

Most accurate provider	FlightHub 3 stars
Most trusted provider	FlightHub 3 stars
Round-trip from	$249 (Delta)
Popular in	December
Cheapest in	September
Average price	$238

Provider with most accurate pricing for Knoxville McGhee Tyson-Syracuse Hancock Intl flight deals.

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Provider most trusted by Cheapflights users for Knoxville McGhee Tyson-Syracuse Hancock Intl flights.

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From Knoxville McGhee Tyson to Syracuse Hancock Intl

Search Deals

Highest demand for flights based on searches. 16% potential increase in price ($61 potential increase over avg. RT price).

Search Deals

Cheapest flight prices on average. 4% potential price decrease ($14 potential savings vs. average RT price).

Search Deals

Average for round-trip flights in April 2025

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Find flight deals from Knoxville to Syracuse

Cheapest flights from Knoxville to Syracuse
Explore the most affordable flight options available from Knoxville to Syracuse. Find the lowest fares from popular airlines and budget airlines, with prices last updated on April 12, 2025.

Thu 6/195:57 pmTYS - SYR

1 stop6h 00mDelta

Mon 6/236:20 amSYR - TYS

1 stop4h 26mDelta

Deal found 4/11

$249

Fri 4/1810:35 amTYS - SYR

1 stop6h 15mAmerican Airlines

Tue 4/225:12 pmSYR - TYS

1 stop6h 33mAmerican Airlines

Deal found 4/11

$389

Thu 6/195:45 amTYS - SYR

2 stops18h 13mUnited Airlines

Mon 6/235:40 pmSYR - TYS

1 stop5h 00mUnited Airlines

Deal found 4/11

$578

Best flights from Knoxville to Syracuse
Discover carefully curated flight deals from Knoxville to Syracuse that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated April 12, 2025.

Thu 6/195:57 pmTYS - SYR

1 stop6h 00mDelta

Mon 6/236:20 amSYR - TYS

1 stop4h 26mDelta

Deal found 4/11

$249

Fri 6/205:57 pmTYS - SYR

2 stops5h 59mAmerican Airlines

Mon 6/235:06 amSYR - TYS

1 stop5h 37mAmerican Airlines

Deal found 4/12

$509

Thu 6/195:45 amTYS - SYR

2 stops18h 13mUnited Airlines

Mon 6/235:40 pmSYR - TYS

1 stop5h 00mUnited Airlines

Deal found 4/11

$578

Last-minute flights from Knoxville to Syracuse
Discover last-minute flight deals from Knoxville to Syracuse. Data last updated April 12, 2025 and is based on user searches.

Fri 4/1810:35 amTYS - SYR

1 stop6h 15mAmerican Airlines

Tue 4/225:12 pmSYR - TYS

1 stop6h 33mAmerican Airlines

Deal found 4/11

$389

Fri 4/181:57 pmTYS - SYR

2 stops10h 28mUnited Airlines

Tue 4/226:05 amSYR - TYS

2 stops7h 17mUnited Airlines

Deal found 4/10

$765

One-way flights from Knoxville to Syracuse
Search for one-way flight options from Knoxville to Syracuse. Find affordable one-way fares based on user searches. Data last updated April 12, 2025.

Sat 4/2610:35 amTYS - SYR

1 stop6h 15mAmerican Airlines

Deal found 4/11

$389

Sat 4/267:00 amTYS - SYR

2 stops9h 15mUnited Airlines

Deal found 4/11

$481

Sat 4/269:19 amTYS - SYR

3 stops46h 47mMultiple Airlines

Deal found 4/11

$523

Cheapflights Fare Finder

Use the filters below to find and compare flights from Knoxville to Syracuse that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

KnoxvilleSyracuse

TYS - SYR

TYSSYR

Knoxville McGhee Tyson

Thu 6/19

5:57 pm-11:57 pm

1 stop6h 00m

Syracuse Hancock Intl

Mon 6/23

6:20 am-10:46 am

1 stop4h 26m

$249

KnoxvilleSyracuse

TYS - SYR

TYSSYR

Knoxville McGhee Tyson

Fri 6/20

5:57 pm-11:56 pm

2 stops5h 59m

Syracuse Hancock Intl

Mon 6/23

5:06 am-10:43 am

1 stop5h 37m

$509

KnoxvilleSyracuse

TYS - SYR

TYSSYR

Knoxville McGhee Tyson

Thu 6/19

5:45 am-11:58 pm

2 stops18h 13m

Syracuse Hancock Intl

Mon 6/23

5:40 pm-10:40 pm

1 stop5h 00m

$578

KnoxvilleSyracuse

TYS - SYR

TYSSYR

Knoxville McGhee Tyson

Sat 4/26

10:35 am-4:50 pm

1 stop6h 15m

$389

KnoxvilleSyracuse

TYS - SYR

TYSSYR

Knoxville McGhee Tyson

Sat 4/26

7:00 am-4:15 pm

2 stops9h 15m

$481

KnoxvilleSyracuse

TYS - SYR

TYSSYR

Knoxville McGhee Tyson

Sat 4/26

9:19 am-8:06 am

3 stops46h 47m

$523

Flights are sorted by cheapest round-trip flights first.

Deals found on 4/11

Compare providers for flights from Knoxville to Syracuse

Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Knoxville to Syracuse in April.

Provider	Price Accuracy	Trust Score*
Expedia	Price Accuracy1 star	Trust Score*3 stars
FlightHub	Price Accuracy3 stars	Trust Score*3 stars
eDreams	Price Accuracy3 stars	Trust Score*3 stars

*The Trust Score is based on feedback from users after their booking experience. It measures overall satisfaction, helping us identify issues like hidden fees, problems during the ticketing process, and the quality of customer service. This score is our best indicator of the provider's quality and reliability.

Most accurate provider: When it comes to deals on Knoxville-Syracuse flights, users find the pricing of FlightHub to be most consistent on Cheapflights vs. FlightHub Users can find the same prices on Knoxville-Syracuse flight deals on Cheapflights vs. FlightHub >95% of the time. Price accuracy is based on data collected from Knoxville-Syracuse flight searches over the past month and is updated monthly.
Most trusted provider: When it comes to deals on Knoxville-Syracuse flights, Cheapflights users trust FlightHub the most. FlightHub has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Knoxville-Syracuse flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.

Best time to book a flight from Knoxville to Syracuse

Have a flexible travel schedule? Discover the best time to fly to Syracuse from Knoxville with our price prediction graph.

Estimated round-trip price

Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Knoxville to Syracuse

What is the cheapest month to book a flight from Knoxville to Syracuse?

Currently, January is the cheapest month in which you can book a flight from Knoxville to Syracuse (average of $272). Flying from Knoxville to Syracuse in July is currently the most expensive (average of $395). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from TYS to SYR?

It’s typically best to fly out from Knoxville to Syracuse in the morning. Doing so could potentially save you 24% on the flight price compared to flying at noon, which is usually more expensive.

Rainfall in Syracuse by month

In terms of precipitation, rainfall in Syracuse ranges from 2.1 - 3.8 inches per month. July is typically the wettest month, when rainfall can reach 3.8 in. February is typically the driest time to visit Syracuse when rainfall is around 2.1 in.

Temperature in Syracuse by month

If weather is an important factor for your trip to Syracuse, use this chart to help with planning. For those seeking warmer temperatures, July is the ideal time of year to visit, when temperatures reach an average of 71.6 F. Travelers looking to avoid the cold should look outside of January, when temperatures are typically at their lowest (around 23.0 F).

Reviews of airlines servicing Syracuse

See what other customers who have flown with Delta, United Airlines and American Airlines from Knoxville to Syracuse have to say. Users can see the overall rating for each airline as well as how each is rated in terms of entertainment options, comfort, food, crew/service, and boarding process.

Delta

8.0

Very good

7,913 reviews

Reviews

1 / 20

10.0

Excellent

Lucy,Nov 2023

ATL - JFK

On time flights; courteous staff; efficient boarding system! Thank you!

Delta

8.0

Very good

7,913 reviews

Delta

8.0

Very good

7,913 reviews

Reviews

1 / 20

10.0

Excellent

Lucy,Nov 2023

ATL - JFK

On time flights; courteous staff; efficient boarding system! Thank you!

United Airlines

7.4

Good

8,644 reviews

Delta

8.0

Very good

7,913 reviews

Reviews

1 / 20

10.0

Excellent

Lucy,Nov 2023

ATL - JFK

On time flights; courteous staff; efficient boarding system! Thank you!

American Airlines

7.2

Good

10,000 reviews

Delta

8.0

Very good

7,913 reviews

Reviews

1 / 20

10.0

Excellent

Lucy,Nov 2023

ATL - JFK

On time flights; courteous staff; efficient boarding system! Thank you!

Related info for your journey

What are the cheapest airlines flying from Knoxville to Syracuse round-trip?
According to our current data, Delta ($249), American Airlines ($509), and United Airlines ($578) offers the cheapest pricing from Knoxville to Syracuse. You may be able to fly from Knoxville to Syracuse for 21% less than the average price by searching for these airlines.
Can I find deals for flights from Knoxville to Syracuse that include hotel bookings?
Yes. In addition to deals on Knoxville to Syracuse flights, Cheapflights offers vacation packages that include both flights and hotel.
How can I find direct flights from Knoxville to Syracuse?
After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Knoxville to Syracuse.
Can I find deals for business class flights from Knoxville to Syracuse?
Yes. Cheapflights offers flight deals from Knoxville to Syracuse by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.
What is the cheapest month to book a flight from Knoxville to Syracuse?
Currently, January is the cheapest month in which you can book a flight from Knoxville to Syracuse (average of $272). Flying from Knoxville to Syracuse in July is currently the most expensive (average of $395). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

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Complete your trip

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Other flights to Syracuse

Top 3 airlines flying from Knoxville to Syracuse

Airline	Cheapest	Average	Flexibility	On-time
Delta	Cheapest$203	Average$294	FlexibilityNo cancel fee	On-timeN/A
United Airlines	Cheapest$223	Average$348	FlexibilityNo cancel fee	On-time69%
American Airlines	Cheapest$228	Average$337	FlexibilityNo cancel fee	On-time71%

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$249+ Cheap flights from Knoxville to Syracuse (TYS - SYR)

This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 6/19. Fares are subject to change and may not be available on all flights or dates of travel.

Find cheap flights from Knoxville to Syracuse with Cheapflights

1. Tell us where you want to go

2. Select your favorite providers

3. Compare prices and book

Cheap flight deals from Knoxville to Syracuse

Most accurate provider

Most trusted provider

Round-trip from

Popular in

Cheapest in

Average price

Find flight deals from Knoxville to Syracuse

Cheapest flights from Knoxville to SyracuseExplore the most affordable flight options available from Knoxville to Syracuse. Find the lowest fares from popular airlines and budget airlines, with prices last updated on April 12, 2025.

Explore the most affordable flight options available from Knoxville to Syracuse. Find the lowest fares from popular airlines and budget airlines, with prices last updated on April 12, 2025.

Cheapflights Fare Finder

Use the filters below to find and compare flights from Knoxville to Syracuse that are best for you.

Compare providers for flights from Knoxville to Syracuse

Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.

Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Knoxville to Syracuse in April.

Best time to book a flight from Knoxville to Syracuse

Have a flexible travel schedule? Discover the best time to fly to Syracuse from Knoxville with our price prediction graph.

Cheapflights Insights

Everything you need to know about your flight from Knoxville to Syracuse

What is the cheapest month to book a flight from Knoxville to Syracuse?

What is the cheapest time of day to fly from TYS to SYR?

Find hourly flight availability from Knoxville to Syracuse. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated April 12, 2025.

Rainfall in Syracuse by month

Plan your trip to Syracuse by taking into account the average rainfall totals by month.

Temperature in Syracuse by month

Plan your trip to Syracuse by taking into account the average temperature totals by month.

Reviews of airlines servicing Syracuse

See what other customers who have flown with Delta, United Airlines and American Airlines from Knoxville to Syracuse have to say. Users can see the overall rating for each airline as well as how each is rated in terms of entertainment options, comfort, food, crew/service, and boarding process.

Related info for your journey

Find useful and relevant information for your journey from Knoxville to Syracuse. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

What are the cheapest airlines flying from Knoxville to Syracuse round-trip?

Can I find deals for flights from Knoxville to Syracuse that include hotel bookings?

How can I find direct flights from Knoxville to Syracuse?

Can I find deals for business class flights from Knoxville to Syracuse?

What is the cheapest month to book a flight from Knoxville to Syracuse?

Traveling to a place near Knoxville?

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Alternative routes for Knoxville to Syracuse

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Top 3 airlines flying from Knoxville to Syracuse

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Cheapest flights from Knoxville to Syracuse
Explore the most affordable flight options available from Knoxville to Syracuse. Find the lowest fares from popular airlines and budget airlines, with prices last updated on April 12, 2025.