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$318+ Cheap flights from Des Moines to Syracuse (DSM - SYR)

This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 4/5. Fares are subject to change and may not be available on all flights or dates of travel.
DSM — SYR
Feb 25 — Mar 41
Tue 2/25
Tue 3/4
1 adult, Economy
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Cheap flight deals from Des Moines to Syracuse

Discover tips and strategies to find the most affordable flight options for your journey from Des Moines (DSM) to Syracuse (SYR). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated February 20, 2025.

Most accurate provider

FlightHub
3 stars

Most trusted provider

FlightHub
3 stars

Round-trip from

$318
(Delta)

Popular in

July

Cheapest in

May

Average price

$323
Provider with most accurate pricing for Des Moines-Syracuse Hancock Intl flight deals.
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Provider most trusted by Cheapflights users for Des Moines-Syracuse Hancock Intl flights.
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From Des Moines to Syracuse Hancock Intl
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Highest demand for flights based on searches. 19% potential increase in price ($94 potential increase over avg. RT price).
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Cheapest flight prices on average. 4% potential price decrease ($16 potential savings vs. average RT price).
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Average for round-trip flights in February 2025
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Find flight deals from Des Moines to Syracuse

Cheapest flights from Des Moines to Syracuse
Explore the most affordable flight options available from Des Moines to Syracuse. Find the lowest fares from popular airlines and budget airlines, with prices last updated on February 20, 2025.

This Delta deal was found by Cheapflights users on 2/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 4/56:20 amDSM - SYR
1 stop4h 32mDelta
Sat 4/126:35 pmSYR - DSM
1 stop5h 24mDelta
Deal found 2/19$318
This American Airlines deal was found by Cheapflights users on 2/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 6/266:03 amDSM - SYR
1 stop4h 12mAmerican Airlines
Wed 7/26:26 amSYR - DSM
1 stop7h 34mAmerican Airlines
Deal found 2/18$374
This eDestinos deal was found by Cheapflights users on 2/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure eDestinos is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 4/57:30 amDSM - SYR
1 stop9h 49mAllegiant Air
Sat 4/125:30 pmSYR - DSM
1 stop22h 57mAllegiant Air
Deal found 2/18$408
This United deal was found by Cheapflights users on 2/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 6/2611:23 amDSM - SYR
1 stop4h 21mUnited Airlines
Wed 7/210:45 amSYR - DSM
2 stops10h 58mUnited Airlines
Deal found 2/18$474
This Mytrip deal was found by Cheapflights users on 2/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 3/163:45 pmDSM - SYR
2 stops24h 45mMultiple Airlines
Thu 3/2010:09 pmSYR - DSM
1 stop26h 06mMultiple Airlines
Deal found 2/19$580

Find flights from Des Moines to Syracuse within your budget

Customize your flight search to find flights from Des Moines to Syracuse that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated February 20, 2025.

Fly from

Des Moines

Fly to

Syracuse

Route

Depart

Return

Price

Des MoinesSyracuse

DSM - SYR

DSMSYR

Des Moines

Sat 4/5

6:20 am-11:52 am

1 stop4h 32m

Syracuse Hancock Intl

Sat 4/12

6:35 pm-10:59 pm

1 stop5h 24m

$318

Des MoinesSyracuse

DSM - SYR

DSMSYR

Des Moines

Thu 6/26

6:03 am-11:15 am

1 stop4h 12m

Syracuse Hancock Intl

Wed 7/2

6:26 am-1:00 pm

1 stop7h 34m

$374

Des MoinesSyracuse

DSM - SYR

DSMSYR

Des Moines

Sat 4/5

7:30 am-6:19 pm

1 stop9h 49m

Syracuse Hancock Intl

Sat 4/12

5:30 pm-3:27 pm

1 stop22h 57m

$408

Des MoinesSyracuse

DSM - SYR

DSMSYR

Des Moines

Thu 6/26

11:23 am-4:44 pm

1 stop4h 21m

Syracuse Hancock Intl

Wed 7/2

10:45 am-8:43 pm

2 stops10h 58m

$474

Des MoinesSyracuse

DSM - SYR

DSMSYR

Des Moines

Sun 3/16

3:45 pm-5:30 pm

2 stops24h 45m

Syracuse Hancock Intl

Thu 3/20

10:09 pm-11:15 pm

1 stop26h 06m

$580

Des MoinesSyracuse

DSM - SYR

DSMSYR

Des Moines

Sun 4/6

7:45 am-10:11 am

1 stop25h 26m

$491

Flights are sorted by cheapest round-trip flights first.

Deals found on 2/19

Compare providers for flights from Des Moines to Syracuse

Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Des Moines to Syracuse in February.
ProviderPrice AccuracyTrust Score*
ExpediaPrice Accuracy1 starTrust Score*3 stars
FlightHubPrice Accuracy3 starsTrust Score*3 stars
MytripPrice Accuracy3 starsTrust Score*3 stars
CheapOairPrice Accuracy1 starTrust Score*3 stars
PricelinePrice Accuracy1 starTrust Score*3 stars

*The Trust Score is based on feedback from users after their booking experience. It measures overall satisfaction, helping us identify issues like hidden fees, problems during the ticketing process, and the quality of customer service. This score is our best indicator of the provider's quality and reliability.

  • Most accurate provider: When it comes to deals on Des Moines-Syracuse flights, users find the pricing of FlightHub to be most consistent on Cheapflights vs. FlightHub Users can find the same prices on Des Moines-Syracuse flight deals on Cheapflights vs. FlightHub >95% of the time. Price accuracy is based on data collected from Des Moines-Syracuse flight searches over the past month and is updated monthly.
  • Most trusted provider: When it comes to deals on Des Moines-Syracuse flights, Cheapflights users trust FlightHub the most. FlightHub has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Des Moines-Syracuse flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.

Best time to book a flight from Des Moines to Syracuse

Have a flexible travel schedule? Discover the best time to fly to Syracuse from Des Moines with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Travel insights for flights from Des Moines to Syracuse

Get recent, data-driven insights about flights from Des Moines to Syracuse including ideal travel times, pricing trends, and more.

What is the cheapest month to book a flight from Des Moines to Syracuse?

Currently, January is the cheapest month in which you can book a flight from Des Moines to Syracuse (average of $272). Flying from Des Moines to Syracuse in July is currently the most expensive (average of $395). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

Rainfall in Syracuse by month

Plan your trip to Syracuse by taking into account the average rainfall totals by month.

In terms of precipitation, rainfall in Syracuse ranges from 2.1 - 3.8 inches per month. July is typically the wettest month, when rainfall can reach 3.8 in. February is typically the driest time to visit Syracuse when rainfall is around 2.1 in.

Temperature in Syracuse by month

Plan your trip to Syracuse by taking into account the average temperature totals by month.

If weather is an important factor for your trip to Syracuse, use this chart to help with planning. For those seeking warmer temperatures, July is the ideal time of year to visit, when temperatures reach an average of 71.6 F. Travelers looking to avoid the cold should look outside of January, when temperatures are typically at their lowest (around 23.0 F).

Reviews of airlines servicing Syracuse

Get insights into the airlines that provide service to Syracuse. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Syracuse. Reviews last updated February 20, 2025.
Delta
8.0
Very good
8,219 reviews

Comfort

8.0

Entertainment

7.9

Food

7.3

Overall

8.0

Crew

8.5

Boarding

8.2

Reviews

1 / 20

10.0
Excellent

Lucy,Nov 2023

ATL - JFK

On time flights; courteous staff; efficient boarding system! Thank you!

Delta
8.0
Very good
8,219 reviews
Delta
8.0
Very good
8,219 reviews

Comfort

8.0

Entertainment

7.9

Food

7.3

Overall

8.0

Crew

8.5

Boarding

8.2

Reviews

1 / 20

10.0
Excellent

Lucy,Nov 2023

ATL - JFK

On time flights; courteous staff; efficient boarding system! Thank you!

United Airlines
7.4
Good
8,765 reviews
Delta
8.0
Very good
8,219 reviews

Comfort

8.0

Entertainment

7.9

Food

7.3

Overall

8.0

Crew

8.5

Boarding

8.2

Reviews

1 / 20

10.0
Excellent

Lucy,Nov 2023

ATL - JFK

On time flights; courteous staff; efficient boarding system! Thank you!

Allegiant Air
7.3
Good
765 reviews
Delta
8.0
Very good
8,219 reviews

Comfort

8.0

Entertainment

7.9

Food

7.3

Overall

8.0

Crew

8.5

Boarding

8.2

Reviews

1 / 20

10.0
Excellent

Lucy,Nov 2023

ATL - JFK

On time flights; courteous staff; efficient boarding system! Thank you!

American Airlines
7.2
Good
10,000 reviews
Delta
8.0
Very good
8,219 reviews

Comfort

8.0

Entertainment

7.9

Food

7.3

Overall

8.0

Crew

8.5

Boarding

8.2

Reviews

1 / 20

10.0
Excellent

Lucy,Nov 2023

ATL - JFK

On time flights; courteous staff; efficient boarding system! Thank you!

Related info for your journey

Find useful and relevant information for your journey from Des Moines to Syracuse. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What are the cheapest airlines flying from Des Moines to Syracuse round-trip?

    Our cheapest airline available from Des Moines to Syracuse is Delta. Our recent data shows that you can find tickets from as low as $318 on this airline. Additional options worth looking into are American Airlines and Allegiant Air, starting at $374 and $408 round-trip. Delta is priced at 19% lower than the current average price of a flight leaving 3 months from now.

  • Can I find deals for flights from Des Moines to Syracuse that include hotel bookings?

    Yes. In addition to deals on Des Moines to Syracuse flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Des Moines to Syracuse?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Des Moines to Syracuse.

  • Can I find deals for business class flights from Des Moines to Syracuse?

    Yes. Cheapflights offers flight deals from Des Moines to Syracuse by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Des Moines to Syracuse?

    Currently, January is the cheapest month in which you can book a flight from Des Moines to Syracuse (average of $272). Flying from Des Moines to Syracuse in July is currently the most expensive (average of $395). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Traveling to a place near Des Moines?

Book flights to Des Moines if you plan to visit one of these locations
Liverpool
Auburn
East Syracuse
Cicero
Waterloo

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Alternative routes for Des Moines to Syracuse

See prices for flight routes from nearby airports that may be better suited for you.
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Waterloo to Newark flights
Waterloo to John F Kennedy Intl flights
Moline to Rochester flights
Cedar Rapids to Elmira flights
Omaha to Binghamton flights
La Crosse to Buffalo flights
Cedar Rapids to Binghamton flights

Top 3 airlines flying from Des Moines to Syracuse

Discover the top 3 airlines that operate flights from Des Moines to Syracuse. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated February 20, 2025.
AirlineCheapestAverageFlexibilityOn-time
American AirlinesCheapest$128Average$319FlexibilityNo cancel feeOn-time71%
DeltaCheapest$261Average$406FlexibilityNo cancel feeOn-timeN/A
United AirlinesCheapest$374Average$561FlexibilityNo cancel feeOn-time69%
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