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St. Louis

$54+ Cheap flights from South Carolina to St. Louis (STL)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 1/18. Fares are subject to change and may not be available on all flights or dates of travel.
CHS — STL
Dec 24 — Dec 311
Tue 12/24
Tue 12/31
1 adult, Economy
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Cheap flight deals from South Carolina to St. Louis

Discover tips and strategies to find the most affordable flight options for your journey from South Carolina (USSC) to St. Louis (STL). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated December 19, 2024.

Round-trip from

$126
(Mytrip)

One-way from

$54
(Cheapflightsfares)
From South Carolina to Lambert-St Louis
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One-way flight from South Carolina to Lambert-St Louis
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Find flight deals from South Carolina to St. Louis

Cheapest flights from South Carolina to St. Louis
Explore the most affordable flight options available from South Carolina to St. Louis. Find the lowest fares from popular airlines and budget airlines, with prices last updated on December 19, 2024.

This Mytrip deal was found by Cheapflights users on 12/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/316:40 pmCLT - STL
1 stop5h 48mFrontier
Fri 1/36:49 pmSTL - CLT
1 stop15h 24mFrontier
Deal found 12/19$296
This United Airlines deal was found by Cheapflights users on 12/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 12/225:40 amCAE - STL
1 stop5h 14mUnited Airlines
Thu 1/21:05 pmSTL - CAE
1 stop5h 24mUnited Airlines
Deal found 12/19$298
This FlightHub deal was found by Cheapflights users on 12/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure FlightHub is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/2610:09 pmCLT - STL
1 stop26h 31mMultiple Airlines
Thu 1/164:28 pmSTL - CLT
1 stop6h 00mMultiple Airlines
Deal found 12/18$307
This American Airlines deal was found by Cheapflights users on 12/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/237:00 amCAE - STL
1 stop7h 03mAmerican Airlines
Thu 1/26:30 amSTL - CAE
1 stop5h 05mAmerican Airlines
Deal found 12/19$323
This American Airlines deal was found by Cheapflights users on 12/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/251:31 pmAGS - STL
1 stop6h 29mAmerican Airlines
Fri 1/32:27 pmSTL - AGS
1 stop4h 11mAmerican Airlines
Deal found 12/17$326
This Delta deal was found by Cheapflights users on 12/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/2512:45 pmMYR - STL
1 stop7h 02mDelta
Wed 1/16:00 amSTL - MYR
1 stop4h 41mDelta
Deal found 12/17$336
This American Airlines deal was found by Cheapflights users on 12/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/257:03 amMYR - STL
2 stops9h 37mAmerican Airlines
Wed 1/15:03 amSTL - MYR
1 stop6h 08mAmerican Airlines
Deal found 12/17$341
This American Airlines deal was found by Cheapflights users on 12/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/315:16 amGSP - STL
1 stop4h 34mAmerican Airlines
Sun 1/52:27 pmSTL - GSP
1 stop6h 03mAmerican Airlines
Deal found 12/18$351
This American Airlines deal was found by Cheapflights users on 12/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/2512:39 pmCLT - STL
Nonstop1h 58mAmerican Airlines
Thu 1/27:30 amSTL - CLT
Nonstop2h 00mAmerican Airlines
Deal found 12/19$375
This Delta deal was found by Cheapflights users on 12/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/255:05 pmCLT - STL
1 stop5h 38mDelta
Thu 1/25:55 pmSTL - CLT
1 stop4h 35mDelta
Deal found 12/19$394
This Delta deal was found by Cheapflights users on 12/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/316:00 amGSP - STL
1 stop4h 08mDelta
Sun 1/56:00 amSTL - GSP
1 stop4h 14mDelta
Deal found 12/18$402
This Southwest deal was found by Cheapflights users on 12/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/312:05 pmGSP - STL
2 stops9h 00mSouthwest
Sun 1/52:30 pmSTL - GSP
2 stops7h 05mSouthwest
Deal found 12/18$412

Find flights from South Carolina to St. Louis within your budget

Customize your flight search to find flights from South Carolina to St. Louis that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated December 19, 2024.

Fly from

Any airport

Fly to

Any airport

Route

Depart

Return

Price

CharlotteSt. Louis

CLT - STL

CLTSTL

Charlotte Douglas

Thu 1/23

7:15 pm-9:16 am

1 stop15h 01m

Lambert-St Louis

Sun 1/26

8:22 am-10:23 am

1 stop25h 01m

$126

CharlotteSt. Louis

CLT - STL

CLTSTL

Charlotte Douglas

Sat 1/18

6:31 pm-11:31 pm

1 stop6h 00m

Lambert-St Louis

Tue 1/21

3:48 pm-5:06 pm

1 stop24h 18m

$170

CharlotteSt. Louis

CLT - STL

CLTSTL

Charlotte Douglas

Mon 1/27

8:55 pm-2:43 pm

2 stops18h 48m

Lambert-St Louis

Sun 2/2

4:28 pm-11:28 pm

1 stop6h 00m

$206

ColumbiaSt. Louis

CAE - STL

CAESTL

Columbia Metropolitan

Sat 1/11

8:11 am-11:47 am

1 stop4h 36m

Lambert-St Louis

Fri 1/17

2:00 pm-8:35 pm

1 stop5h 35m

$248

ColumbiaSt. Louis

CAE - STL

CAESTL

Columbia Metropolitan

Wed 1/15

4:09 pm-10:09 pm

2 stops7h 00m

Lambert-St Louis

Mon 1/20

5:23 am-10:43 am

1 stop4h 20m

$253

Myrtle BeachSt. Louis

MYR - STL

MYRSTL

Myrtle Beach Intl

Thu 1/9

9:11 am-2:43 pm

1 stop6h 32m

Lambert-St Louis

Sun 1/12

4:28 pm-3:01 pm

2 stops21h 33m

$273

GreenvilleSt. Louis

GSP - STL

GSPSTL

Greenville

Wed 1/15

7:14 am-11:47 am

1 stop5h 33m

Lambert-St Louis

Sat 1/18

10:59 am-3:58 pm

1 stop3h 59m

$291

GreenvilleSt. Louis

GSP - STL

GSPSTL

Greenville

Wed 1/15

4:21 pm-7:23 pm

1 stop4h 02m

Lambert-St Louis

Sat 1/18

11:47 am-7:04 pm

2 stops6h 17m

$296

AugustaSt. Louis

AGS - STL

AGSSTL

Augusta Bush Field

Wed 1/15

5:00 am-2:07 pm

2 stops10h 07m

Lambert-St Louis

Sat 1/18

9:20 am-2:11 pm

1 stop3h 51m

$312

CharlestonSt. Louis

CHS - STL

CHSSTL

Charleston

Sat 1/18

6:00 am-12:31 pm

1 stop7h 31m

Lambert-St Louis

Sun 1/19

6:00 am-11:25 am

1 stop4h 25m

$312

Flights are sorted by cheapest round-trip flights first.

Deals found on 12/18

Showing 1-10 of 54 results
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Best time to book a flight from South Carolina to St. Louis

Have a flexible travel schedule? Discover the best time to fly to St. Louis from South Carolina with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Travel insights for flights from South Carolina to St. Louis

Get recent, data-driven insights about flights from South Carolina to St. Louis including ideal travel times, pricing trends, and more.

What is the cheapest month to book a flight from South Carolina to St. Louis?

Currently, August is the cheapest month in which you can book a flight from South Carolina to St. Louis (average of $311). Flying from South Carolina to St. Louis in March is currently the most expensive (average of $356). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from SC to STL?

Find hourly flight availability from South Carolina to St. Louis. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated December 19, 2024.

When flying from South Carolina to St. Louis, the time of day you decide to fly out makes little to no difference towards the overall price you’ll pay on tickets.

Rainfall in St. Louis by month

Plan your trip to St. Louis by taking into account the average rainfall totals by month.

In terms of precipitation, rainfall in St. Louis ranges from 2.2 - 4.7 inches per month. May is typically the wettest month, when rainfall can reach 4.7 in. February is typically the driest time to visit St. Louis when rainfall is around 2.2 in.

Temperature in St. Louis by month

Plan your trip to St. Louis by taking into account the average temperature totals by month.

If weather is an important factor for your trip to St. Louis, use this chart to help with planning. For those seeking warmer temperatures, July is the ideal time of year to visit, when temperatures reach an average of 80.6 F. Travelers looking to avoid the cold should look outside of January, when temperatures are typically at their lowest (around 32.0 F).

Reviews of airlines servicing St. Louis

Get insights into the airlines that provide service to St. Louis. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to St. Louis. Reviews last updated December 19, 2024.
Read through reviews of airlines operating flights from South Carolina to St. Louis, such as Frontier, Spirit Airlines and Delta. Reviews also offer insight into each airline's entertainment options, comfort, food, crew/service, and boarding process.
Southwest
8.1
Very good
4,836 reviews

Comfort

8.1

Crew

8.7

Overall

8.1

Food

7.2

Boarding

8.2

Entertainment

7.7

Reviews

1 / 10

We BARELY made the connection and when we got onboard we were treated like disobedient children who should have arrived earlier because we had to ask other passengers to move so we could sit with our kids. The flight attendants on the first flight were nice but the second one, they were snippy and fairly rude.

Southwest
8.1
Very good
4,836 reviews
Southwest
8.1
Very good
4,836 reviews

Comfort

8.1

Crew

8.7

Overall

8.1

Food

7.2

Boarding

8.2

Entertainment

7.7

Reviews

1 / 10

We BARELY made the connection and when we got onboard we were treated like disobedient children who should have arrived earlier because we had to ask other passengers to move so we could sit with our kids. The flight attendants on the first flight were nice but the second one, they were snippy and fairly rude.

Alaska Airlines
8.0
Very good
9,551 reviews
Southwest
8.1
Very good
4,836 reviews

Comfort

8.1

Crew

8.7

Overall

8.1

Food

7.2

Boarding

8.2

Entertainment

7.7

Reviews

1 / 10

We BARELY made the connection and when we got onboard we were treated like disobedient children who should have arrived earlier because we had to ask other passengers to move so we could sit with our kids. The flight attendants on the first flight were nice but the second one, they were snippy and fairly rude.

Delta
8.0
Very good
8,600 reviews
Southwest
8.1
Very good
4,836 reviews

Comfort

8.1

Crew

8.7

Overall

8.1

Food

7.2

Boarding

8.2

Entertainment

7.7

Reviews

1 / 10

We BARELY made the connection and when we got onboard we were treated like disobedient children who should have arrived earlier because we had to ask other passengers to move so we could sit with our kids. The flight attendants on the first flight were nice but the second one, they were snippy and fairly rude.

United Airlines
7.4
Good
9,048 reviews
Southwest
8.1
Very good
4,836 reviews

Comfort

8.1

Crew

8.7

Overall

8.1

Food

7.2

Boarding

8.2

Entertainment

7.7

Reviews

1 / 10

We BARELY made the connection and when we got onboard we were treated like disobedient children who should have arrived earlier because we had to ask other passengers to move so we could sit with our kids. The flight attendants on the first flight were nice but the second one, they were snippy and fairly rude.

American Airlines
7.2
Good
10,000 reviews
Southwest
8.1
Very good
4,836 reviews

Comfort

8.1

Crew

8.7

Overall

8.1

Food

7.2

Boarding

8.2

Entertainment

7.7

Reviews

1 / 10

We BARELY made the connection and when we got onboard we were treated like disobedient children who should have arrived earlier because we had to ask other passengers to move so we could sit with our kids. The flight attendants on the first flight were nice but the second one, they were snippy and fairly rude.

Related info for your journey

Find useful and relevant information for your journey from South Carolina to St. Louis. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly into for flights to St. Louis from South Carolina?

    For a flight from South Carolina to St. Louis, you will be flying into Lambert-St Louis. Lambert-St Louis (STL) is just 12.7 mi from the center of the city.

  • What are the cheapest airlines to fly from South Carolina to St. Louis one-way?

    To fly one-way, consider booking your trip with Frontier, which is currently one of the cheapest options available, starting at $54. Spirit Airlines flights start at $86 while deals on Delta start at $151 one-way.

  • What are the most popular routes from South Carolina to St. Louis?

    The most popular flight routes from South Carolina to St. Louis are Charlotte Douglas - Lambert-St Louis, Columbia Metropolitan - Lambert-St Louis and Savannah/Hilton Head - Lambert-St Louis.

  • Can I find deals for flights from South Carolina to St. Louis that include hotel bookings?

    Yes. In addition to deals on South Carolina to St. Louis flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from South Carolina to St. Louis?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from South Carolina to St. Louis.

  • Can I find deals for business class flights from South Carolina to St. Louis?

    Yes. Cheapflights offers flight deals from South Carolina to St. Louis by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from South Carolina to St. Louis?

    Currently, August is the cheapest month in which you can book a flight from South Carolina to St. Louis (average of $311). Flying from South Carolina to St. Louis in March is currently the most expensive (average of $356). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

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Alternative routes for South Carolina to St. Louis

See prices for flight routes from nearby airports that may be better suited for you.
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Top 4 airlines flying from South Carolina to St. Louis

Discover the top 4 airlines that operate flights from South Carolina to St. Louis. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated December 19, 2024.
AirlineCheapestAverageFlexibilityOn-time
Spirit AirlinesCheapest$147Average$250FlexibilityNo cancel feeOn-time65%
American AirlinesCheapest$178Average$354FlexibilityNo cancel feeOn-time71%
DeltaCheapest$231Average$367FlexibilityNo cancel feeOn-timeN/A
SouthwestCheapest$280Average$364FlexibilityNo cancel feeOn-time63%
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