HomeSearch by dateVacation packagesHotelsFlight dealsCar rentalTravel tips & news
St. Louis

$61+ Cheap flights from San Diego to St. Louis (SAN - STL)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 4/10. Fares are subject to change and may not be available on all flights or dates of travel.
SAN — STL
Feb 25 — Mar 41
Tue 2/25
Tue 3/4
1 adult, Economy
We work with more than 300 partners to bring you better travel deals

Find cheap flights from San Diego to St. Louis with Cheapflights

1. Tell us where you want to go
Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”
2. Select your favorite providers
We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.
3. Compare prices and book
Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.

The best prices from San Diego to Lambert-St Louis are usually found in August or May, booked 66 days in advance, depart on a Wednesday or Thursday and return on a Friday

Cheap flight deals from San Diego to St. Louis

Discover tips and strategies to find the most affordable flight options for your journey from San Diego (SAN) to St. Louis (STL). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated February 20, 2025.

Most accurate provider

FlightHub
3 stars

Most trusted provider

FlightHub
3 stars

Round-trip from

$188
(American Airlines)

One-way from

$61
(Frontier)

Popular in

December

Cheapest in

August

Average price

$337

Good round-trip deal

$416 or less

Good one-way deal

$232 or less
Provider with most accurate pricing for San Diego-Lambert-St Louis flight deals.
Search Deals
Provider most trusted by Cheapflights users for San Diego-Lambert-St Louis flights.
Search Deals
From San Diego to Lambert-St Louis
Search Deals
One-way flight from San Diego to Lambert-St Louis
Search Deals
Highest demand for flights based on searches. 12% potential increase in price ($49 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 2% potential price decrease ($10 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in February 2025
Search Deals
Price to beat on a round-trip flight from San Diego to Lambert-St Louis.
Search Deals
Price to beat on a one-way flight from San Diego to Lambert-St Louis.
Search Deals

Find flight deals from San Diego to St. Louis

Cheapest flights from San Diego to St. Louis
Explore the most affordable flight options available from San Diego to St. Louis. Find the lowest fares from popular airlines and budget airlines, with prices last updated on February 20, 2025.

This American Airlines deal was found by Cheapflights users on 2/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 3/186:30 amSAN - STL
1 stop8h 11mAmerican Airlines
Tue 3/255:37 pmSTL - SAN
1 stop6h 34mAmerican Airlines
Deal found 2/19$188
This CheapOair deal was found by Cheapflights users on 2/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 3/38:08 pmSAN - STL
1 stop19h 28mFrontier
Wed 3/56:43 pmSTL - SAN
1 stop26h 34mFrontier
Deal found 2/18$200
This Booking.com deal was found by Cheapflights users on 2/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Booking.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 3/206:20 pmSAN - STL
1 stop15h 14mMultiple Airlines
Mon 3/246:55 pmSTL - SAN
1 stop26h 22mMultiple Airlines
Deal found 2/19$255
This Hawaiian Airlines deal was found by Cheapflights users on 2/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Hawaiian Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/2511:30 amSAN - STL
1 stop10h 26mHawaiian Airlines
Sun 9/287:00 amSTL - SAN
1 stop9h 17mHawaiian Airlines
Deal found 2/19$276
This Delta deal was found by Cheapflights users on 2/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 3/1410:00 pmSAN - STL
1 stop9h 36mDelta
Mon 3/175:35 pmSTL - SAN
1 stop7h 52mDelta
Deal found 2/18$277
This United Airlines deal was found by Cheapflights users on 2/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 4/207:00 amSAN - STL
1 stop6h 47mUnited Airlines
Tue 4/294:45 pmSTL - SAN
2 stops9h 14mUnited Airlines
Deal found 2/19$282
This Alaska Airlines deal was found by Cheapflights users on 2/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Alaska Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 3/126:15 amSAN - STL
2 stops15h 44mAlaska Airlines
Wed 3/196:44 amSTL - SAN
1 stop8h 03mAlaska Airlines
Deal found 2/19$318
This Southwest deal was found by Cheapflights users on 2/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 4/206:20 amSAN - STL
1 stop7h 30mSouthwest
Tue 4/2912:15 pmSTL - SAN
Nonstop3h 55mSouthwest
Deal found 2/19$370
This Mytrip deal was found by Cheapflights users on 2/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 3/16:15 amSAN - STL
3 stops30h 27mSpirit Airlines
Tue 3/44:00 pmSTL - SAN
3 stops43h 12mSpirit Airlines
Deal found 2/19$416

Find flights from San Diego to St. Louis within your budget

Customize your flight search to find flights from San Diego to St. Louis that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated February 20, 2025.

Fly from

San Diego

Fly to

St. Louis

Route

Depart

Return

Price

San DiegoSt. Louis

SAN - STL

SANSTL

San Diego

Tue 3/18

6:30 am-4:41 pm

1 stop8h 11m

Lambert-St Louis

Tue 3/25

5:37 pm-10:11 pm

1 stop6h 34m

$188

San DiegoSt. Louis

SAN - STL

SANSTL

San Diego

Mon 3/3

8:08 pm-5:36 pm

1 stop19h 28m

Lambert-St Louis

Wed 3/5

6:43 pm-7:17 pm

1 stop26h 34m

$200

San DiegoSt. Louis

SAN - STL

SANSTL

San Diego

Thu 3/20

6:20 pm-11:34 am

1 stop15h 14m

Lambert-St Louis

Mon 3/24

6:55 pm-7:17 pm

1 stop26h 22m

$255

San DiegoSt. Louis

SAN - STL

SANSTL

San Diego

Fri 3/14

10:00 pm-9:36 am

1 stop9h 36m

Lambert-St Louis

Mon 3/17

5:35 pm-11:27 pm

1 stop7h 52m

$277

San DiegoSt. Louis

SAN - STL

SANSTL

San Diego

Sun 4/20

7:00 am-3:47 pm

1 stop6h 47m

Lambert-St Louis

Tue 4/29

4:45 pm-11:59 pm

2 stops9h 14m

$282

San DiegoSt. Louis

SAN - STL

SANSTL

San Diego

Wed 3/12

6:15 am-11:59 pm

2 stops15h 44m

Lambert-St Louis

Wed 3/19

6:44 am-12:47 pm

1 stop8h 03m

$318

San DiegoSt. Louis

SAN - STL

SANSTL

San Diego

Sun 4/20

6:20 am-3:50 pm

1 stop7h 30m

Lambert-St Louis

Tue 4/29

12:15 pm-2:10 pm

Nonstop3h 55m

$370

San DiegoSt. Louis

SAN - STL

SANSTL

San Diego

Sat 3/1

6:15 am-2:42 pm

3 stops30h 27m

Lambert-St Louis

Tue 3/4

4:00 pm-9:12 am

3 stops43h 12m

$416

San DiegoSt. Louis

SAN - STL

SANSTL

San Diego

Thu 4/10

7:39 pm-9:06 am

1 stop11h 27m

$61

San DiegoSt. Louis

SAN - STL

SANSTL

San Diego

Mon 3/17

5:15 pm-12:32 am

1 stop5h 17m

$139

Flights are sorted by cheapest round-trip flights first.

Deals found on 2/19

Showing 1-10 of 16 results
1
2

Compare providers for flights from San Diego to St. Louis

Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from San Diego to St. Louis in February.
ProviderPrice AccuracyTrust Score*
ExpediaPrice Accuracy1 starTrust Score*3 stars
FlightHubPrice Accuracy3 starsTrust Score*3 stars
eDreamsPrice Accuracy3 starsTrust Score*3 stars
CheapfaremartPrice Accuracy-Trust Score*3 stars
PricelinePrice Accuracy1 starTrust Score*3 stars
CheapOairPrice Accuracy1 starTrust Score*3 stars
FlightnetworkPrice Accuracy-Trust Score*3 stars

*The Trust Score is based on feedback from users after their booking experience. It measures overall satisfaction, helping us identify issues like hidden fees, problems during the ticketing process, and the quality of customer service. This score is our best indicator of the provider's quality and reliability.

  • Most accurate provider: When it comes to deals on San Diego-St. Louis flights, users find the pricing of FlightHub to be most consistent on Cheapflights vs. FlightHub Users can find the same prices on San Diego-St. Louis flight deals on Cheapflights vs. FlightHub >95% of the time. Price accuracy is based on data collected from San Diego-St. Louis flight searches over the past month and is updated monthly.
  • Most trusted provider: When it comes to deals on San Diego-St. Louis flights, Cheapflights users trust FlightHub the most. FlightHub has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for San Diego-St. Louis flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.

Best time to book a flight from San Diego to St. Louis

Have a flexible travel schedule? Discover the best time to fly to St. Louis from San Diego with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Travel insights for flights from San Diego to St. Louis

Get recent, data-driven insights about flights from San Diego to St. Louis including ideal travel times, pricing trends, and more.

How far ahead should I book a flight from San Diego to St. Louis?

Use this chart to determine the optimal time to book a round-trip flight from San Diego to St. Louis. Price data was last updated on February 14, 2025.

The best time to book flights from San Diego to St. Louis is 66 days before your desired departure date. The cost of your flight will likely increase significantly if you book two weeks in advance of your flight.

What is the cheapest month to book a flight from San Diego to St. Louis?

Currently, August is the cheapest month in which you can book a flight from San Diego to St. Louis (average of $311). Flying from San Diego to St. Louis in March is currently the most expensive (average of $356). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from SAN to STL?

Find hourly flight availability from San Diego to St. Louis. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated February 20, 2025.

A simple way to save on the total cost of your ticket is to fly from San Diego to St. Louis in the evening. If you’re flexible enough to do this you can expect to save up to 59% on your trip compared to booking a flight in the afternoon.

What is the cheapest day to fly from San Diego to St. Louis?

Use this chart to determine the cheapest time to fly round-trip from San Diego to St. Louis. Price data was last updated on February 16, 2025.

Travelers seeking maximum savings on their San Diego to St. Louis flight should consider departing on Wednesday evenings when fares are most often at their lowest. Friday afternoons flights should be avoided if possible as fares are typically the most expensive at this time.

Rainfall in St. Louis by month

Plan your trip to St. Louis by taking into account the average rainfall totals by month.

In terms of precipitation, rainfall in St. Louis ranges from 2.2 - 4.7 inches per month. May is typically the wettest month, when rainfall can reach 4.7 in. February is typically the driest time to visit St. Louis when rainfall is around 2.2 in.

Temperature in St. Louis by month

Plan your trip to St. Louis by taking into account the average temperature totals by month.

If weather is an important factor for your trip to St. Louis, use this chart to help with planning. For those seeking warmer temperatures, July is the ideal time of year to visit, when temperatures reach an average of 80.6 F. Travelers looking to avoid the cold should look outside of January, when temperatures are typically at their lowest (around 32.0 F).

Reviews of airlines servicing St. Louis

Get insights into the airlines that provide service to St. Louis. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to St. Louis. Reviews last updated February 20, 2025.
To help decide which airline to fly from San Diego to St. Louis, see what other customers have to say about Southwest, Alaska Airlines and Delta. Users have also rated airlines in terms of entertainment options, comfort, food, crew/service, and boarding process.
Southwest
8.1
Very good
4,413 reviews

Boarding

8.2

Comfort

8.1

Overall

8.1

Entertainment

7.6

Food

7.1

Crew

8.7

Reviews

1 / 20

2.0
Mediocre

Anonymous,Feb 2025

MCO - STL

Cancelled at last minute, SWA unable to assist in formulating alternate plans. Wound up renting a car and driving 13 hours to beat bad weather forecast at home. Not SWA’s fault that there was significant bad weather across the country.

Southwest
8.1
Very good
4,413 reviews
Southwest
8.1
Very good
4,413 reviews

Boarding

8.2

Comfort

8.1

Overall

8.1

Entertainment

7.6

Food

7.1

Crew

8.7

Reviews

1 / 20

2.0
Mediocre

Anonymous,Feb 2025

MCO - STL

Cancelled at last minute, SWA unable to assist in formulating alternate plans. Wound up renting a car and driving 13 hours to beat bad weather forecast at home. Not SWA’s fault that there was significant bad weather across the country.

Alaska Airlines
8.0
Very good
9,691 reviews
Southwest
8.1
Very good
4,413 reviews

Boarding

8.2

Comfort

8.1

Overall

8.1

Entertainment

7.6

Food

7.1

Crew

8.7

Reviews

1 / 20

2.0
Mediocre

Anonymous,Feb 2025

MCO - STL

Cancelled at last minute, SWA unable to assist in formulating alternate plans. Wound up renting a car and driving 13 hours to beat bad weather forecast at home. Not SWA’s fault that there was significant bad weather across the country.

Delta
8.0
Very good
8,227 reviews
Southwest
8.1
Very good
4,413 reviews

Boarding

8.2

Comfort

8.1

Overall

8.1

Entertainment

7.6

Food

7.1

Crew

8.7

Reviews

1 / 20

2.0
Mediocre

Anonymous,Feb 2025

MCO - STL

Cancelled at last minute, SWA unable to assist in formulating alternate plans. Wound up renting a car and driving 13 hours to beat bad weather forecast at home. Not SWA’s fault that there was significant bad weather across the country.

United Airlines
7.4
Good
8,768 reviews
Southwest
8.1
Very good
4,413 reviews

Boarding

8.2

Comfort

8.1

Overall

8.1

Entertainment

7.6

Food

7.1

Crew

8.7

Reviews

1 / 20

2.0
Mediocre

Anonymous,Feb 2025

MCO - STL

Cancelled at last minute, SWA unable to assist in formulating alternate plans. Wound up renting a car and driving 13 hours to beat bad weather forecast at home. Not SWA’s fault that there was significant bad weather across the country.

American Airlines
7.2
Good
10,000 reviews
Southwest
8.1
Very good
4,413 reviews

Boarding

8.2

Comfort

8.1

Overall

8.1

Entertainment

7.6

Food

7.1

Crew

8.7

Reviews

1 / 20

2.0
Mediocre

Anonymous,Feb 2025

MCO - STL

Cancelled at last minute, SWA unable to assist in formulating alternate plans. Wound up renting a car and driving 13 hours to beat bad weather forecast at home. Not SWA’s fault that there was significant bad weather across the country.

Related info for your journey

Find useful and relevant information for your journey from San Diego to St. Louis. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How popular is this San Diego to St. Louis flight route?

    Flights from San Diego to Lambert-St Louis have been viewed 8 times in the past calendar month.

  • What are the cheapest airlines flying from San Diego to St. Louis round-trip?

    Cheapflights users have booked flights from San Diego to St. Louis round-trip from $188. Other airlines that can offer you cheap pricing are Frontier, from $200, and Delta, from $277. American Airlines is priced at 45% lower than the current average price of a flight leaving 3 months from now.

  • What are the cheapest airlines to fly from San Diego to St. Louis one-way?

    For one-way options, check prices for Frontier. According to our data, you can fly for as low as $61. Users have also found prices from $139 and $170 on Delta and American Airlines, respectively.

  • What are the cheapest flights from San Diego to St. Louis?

    Looking for the cheapest flight from San Diego to St. Louis? While on average our users pay $367, our data indicates the cheapest price to be $204. The most popular route (San Diego - Lambert-St Louis), is priced around $199.

  • Where are the most common layover locations when flying from San Diego to St. Louis?

    Of the flights from San Diego to St. Louis that have layovers, most of them stop in Phoenix.

  • What are some popular things to do or see while on a layover in Phoenix?

    Chase Field, Desert Ridge Marketplace, and Phoenix Symphony Hall are currently the most popular points of interest in Phoenix at the moment. Those on a layover in Phoenix interested in visiting Chase Field, Desert Ridge Marketplace, or Phoenix Symphony Hall can do so by traveling 4.0 mi, 16.7 mi, and 4.3 mi, respectively from Phoenix Sky Harbor Intl. Travelers can book a car rental at Phoenix Sky Harbor Intl for about $55 per day to make their sightseeing more efficient.

  • Where are the least popular layover locations for San Diego to St. Louis flights?

    San Diego to St. Louis flights have a layover in Denver the least frequently.

  • Can I find deals for flights from San Diego to St. Louis that include hotel bookings?

    Yes. In addition to deals on San Diego to St. Louis flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from San Diego to St. Louis?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from San Diego to St. Louis.

  • Can I find deals for business class flights from San Diego to St. Louis?

    Yes. Cheapflights offers flight deals from San Diego to St. Louis by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from San Diego to St. Louis?

    Currently, August is the cheapest month in which you can book a flight from San Diego to St. Louis (average of $311). Flying from San Diego to St. Louis in March is currently the most expensive (average of $356). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Traveling to a place near San Diego?

Book flights to San Diego if you plan to visit one of these locations
Fenton
Fairview Heights
Maryland Heights
Collinsville
Wentzville
Eureka
St. Peters
Festus
Alton
Farmington
Chesterfield

Browse thousands of different options on Cheapflights for your next trip

Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.

Alternative routes for San Diego to St. Louis

See prices for flight routes from nearby airports that may be better suited for you.
Los Angeles to St. Louis flights
Los Angeles to Kansas City flights
San Francisco to St. Louis flights
San Francisco to Kansas City flights
Ontario to Kansas City flights
Ontario to St. Louis flights
Las Vegas to Kansas City flights
Las Vegas to St. Louis flights
San Diego to Kansas City flights
San Jose to Kansas City flights
Burbank to Kansas City flights
Sacramento to Kansas City flights
Santa Ana to St. Louis flights
Long Beach to St. Louis flights
Oakland to Kansas City flights
San Jose to St. Louis flights
Santa Ana to Kansas City flights
Sacramento to St. Louis flights
Sacramento to Springfield flights
Oakland to St. Louis flights
Reno to Kansas City flights
Burbank to St. Louis flights
San Francisco to Springfield flights
Los Angeles to Springfield flights
Ontario to Springfield flights
Palm Springs to Kansas City flights
Fresno to St. Louis flights
Long Beach to Kansas City flights
Santa Ana to Springfield flights
Fresno to Kansas City flights
San Jose to Springfield flights
Palm Springs to St. Louis flights
San Diego to Springfield flights
Arcata to Branson flights
Medford to Kansas City flights
Los Angeles to Columbia flights
Fresno to Springfield flights
Long Beach to Springfield flights
Oakland to Springfield flights
Bakersfield to St. Louis flights
San Jose to Joplin flights
Palm Springs to Springfield flights
Medford to St. Louis flights
San Luis Obispo to Kansas City flights
Ontario to Joplin flights
Los Angeles to Joplin flights
San Francisco to Joplin flights
Sacramento to Joplin flights
Santa Barbara to St. Louis flights

Top 5 airlines flying from San Diego to St. Louis

Discover the top 5 airlines that operate flights from San Diego to St. Louis. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated February 20, 2025.
AirlineCheapestAverageFlexibilityOn-time
FrontierCheapest$108Average$233FlexibilityNo cancel feeOn-time62%
DeltaCheapest$213Average$293FlexibilityNo cancel feeOn-timeN/A
American AirlinesCheapest$235Average$374FlexibilityNo cancel feeOn-time71%
United AirlinesCheapest$256Average$344FlexibilityNo cancel feeOn-time69%
SouthwestCheapest$343Average$475FlexibilityNo cancel feeOn-time63%
100% Free
Cheapflights is completely free to use, so you can start saving the moment you arrive.
Book with Flexibility
Our users can plan ahead with confidence and find flights with no change fees
Travel Smart
Millions of people come to us for their flight needs every year. We help make travel planning easy by providing useful insights and data-driven graphs that can inform your decisions.