What are the cheapest airlines flying from Portland to St. Louis round-trip?

Currently priced at $227, American Airlines will fly you from Portland to St. Louis and back. In addition to American Airlines, many other airlines offer competitively priced options for your trip. Search Cheapflights for deals from Delta and United Airlines - these airlines can fly you to your destination from $251 and $262, respectively. Users have found that American Airlines is 41% cheaper than the other options available to this destination.

What are the cheapest airlines to fly from Portland to St. Louis one-way?

To fly one-way, consider booking your trip with United Airlines, which is currently one of the cheapest options available, starting at $109. Alaska Airlines flights start at $111 while deals on American Airlines start at $112 one-way.

What are the cheapest flights from Portland to St. Louis?

Looking at all options, your cheapest flight can be booked for $209. While the most popular route (Portland - Lambert-St Louis) can be booked for $227 on average our data indicates $209 when flying from Portland to St. Louis.

What are the most popular airlines that fly from Portland to St. Louis?

Before booking your flight from Portland to St. Louis check out the most popular airlines for this route: American Airlines, Alaska Airlines or Delta.

Where are the most common layover locations when flying from Portland to St. Louis?

Portland to St. Louis flights have a layover in Salt Lake City most of the time.

Where are the least popular layover locations for Portland to St. Louis flights?

Of the flights from Portland to St. Louis that have layovers, the fewest flights stop in Denver.

What are some popular things to do or see while on a layover in Salt Lake City?

If you're on a layover in Salt Lake City and looking for things to do, consider visiting Temple Square, Abravanel Hall, or Salt Lake Temple. Temple Square, Abravanel Hall, and Salt Lake Temple are located about 4.7 mi, 4.7 mi, and 4.8 mi, respectively from Salt Lake City. Travelers can rent a car at Salt Lake City for an average daily rate of $55 to make sightseeing during their layover a little easier.

What is the cheapest day to fly round-trip from Portland to St. Louis?

Travelers have found that booking a Thursday departure is the best way to save up to 49% on the cost of booking your flights compared to booking on days of the week where this route is of high demand.

How far in advance should I book a flight from Portland to St. Louis?

To save on the cost of your flight from Portland to St. Louis, book at least 31 days before your planned departure. Booking around this time can save you about 107% on the cost of this flight compared to booking a flight leaving this week. We have found prices from $303 if you need a flight within two weeks. For flights within the next 72 hours, you can find tickets from as low as $452.

What is the cheapest month to fly from Portland to St. Louis?

January can be a great time to fly to St. Louis from Portland with a flight ticket averaging about $386. Cheapflights users have found deals in the month of January for as cheap as $198. The most expensive prices can be found in the month of December.

Most accurate provider : When it comes to deals on Portland-St. Louis flights, users find the pricing of FlightHub to be most consistent on Cheapflights vs. FlightHub Users can find the same prices on Portland-St. Louis flight deals on Cheapflights vs. FlightHub >95% of the time. Price accuracy is based on data collected from Portland-St. Louis flight searches over the past month and is updated monthly.

Most trusted provider : When it comes to deals on Portland-St. Louis flights, Cheapflights users trust FlightHub the most. FlightHub has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Portland-St. Louis flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.

Can I find deals for flights from Portland to St. Louis that include hotel bookings?

Yes. In addition to deals on Portland to St. Louis flights, Cheapflights offers vacation packages that include both flights and hotel.

How can I find direct flights from Portland to St. Louis?

After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Portland to St. Louis.

Can I find deals for business class flights from Portland to St. Louis?

Yes. Cheapflights offers flight deals from Portland to St. Louis by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

$109+ Save on Flights from Portland to St. Louis

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Find cheap flights from Portland to St. Louis with Cheapflights

1. Tell us where you want to go

Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”

2. Select your favorite providers

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Cheapflights Tip: The best prices from Portland to Lambert-St Louis are usually found in January or September, booked 89 days in advance, depart on a Thursday or Monday and return on a Tuesday

Cheap flight deals from Portland to St. Louis

Most accurate provider	FlightHub 3 stars
Most trusted provider	FlightHub 3 stars
Round-trip from	$227 (American Airlines)
One-way from	$109 (United Airlines)
Popular in	December
Cheapest in	January
Average price	$479
Good one-way deal	$209 or less

Provider with most accurate pricing for Portland-Lambert-St Louis flight deals.

Search Deals

Provider most trusted by Cheapflights users for Portland-Lambert-St Louis flights.

Search Deals

From Portland to Lambert-St Louis

Search Deals

One-way flight from Portland to Lambert-St Louis

Search Deals

Highest demand for flights based on searches. 5% potential increase in price ($23 potential increase over avg. RT price).

Search Deals

Cheapest flight prices on average. 2% potential price decrease ($11 potential savings vs. average RT price).

Search Deals

Average for round-trip flights in March 2025

Search Deals

Price to beat on a one-way flight from Portland to Lambert-St Louis.

Search Deals

Find flight deals from Portland to St. Louis

Cheapest flights from Portland to St. Louis
Explore the most affordable flight options available from Portland to St. Louis. Find the lowest fares from popular airlines and budget airlines, with prices last updated on March 25, 2025.

Thu 5/112:03 pmPDX - STL

1 stop9h 13mAmerican Airlines

Fri 5/26:20 pmSTL - PDX

1 stop7h 42mAmerican Airlines

Deal found 3/24

$227

Wed 5/145:00 pmPDX - STL

1 stop5h 33mDelta

Wed 5/286:05 pmSTL - PDX

1 stop7h 20mDelta

Deal found 3/24

$251

Fri 5/2311:59 pmPDX - STL

1 stop8h 13mUnited Airlines

Sun 5/255:00 amSTL - PDX

1 stop6h 42mUnited Airlines

Deal found 3/24

$262

Thu 4/36:40 amPDX - STL

1 stop24h 26mFrontier

Mon 4/76:51 pmSTL - PDX

1 stop7h 46mFrontier

Deal found 3/24

$300

Tue 4/2910:47 amPDX - STL

2 stops11h 12mAlaska Airlines

Wed 5/76:30 amSTL - PDX

1 stop6h 22mAlaska Airlines

Deal found 3/24

$318

Thu 5/11:30 pmPDX - STL

2 stops9h 20mSouthwest

Sun 5/47:30 pmSTL - PDX

1 stop7h 05mSouthwest

Deal found 3/24

$320

Thu 5/156:30 pmPDX - STL

1 stop15h 07mMultiple Airlines

Mon 5/196:53 pmSTL - PDX

1 stop7h 45mMultiple Airlines

Deal found 3/24

$331

Thu 6/2611:59 pmPDX - STL

1 stop9h 37mSun Country Air

Sun 6/296:00 amSTL - PDX

1 stop18h 46mSun Country Air

Deal found 3/23

$355

Sat 4/267:01 pmPDX - STL

2 stops20h 14mSpirit Airlines

Sat 5/1710:10 amSTL - PDX

2 stops32h 35mSpirit Airlines

Deal found 3/24

$562

Best flights from Portland to St. Louis
Discover carefully curated flight deals from Portland to St. Louis that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated March 25, 2025.

Thu 5/112:03 pmPDX - STL

1 stop9h 13mAmerican Airlines

Mon 5/55:20 amSTL - PDX

1 stop7h 30mAmerican Airlines

Deal found 3/24

$227

Wed 5/145:00 pmPDX - STL

1 stop5h 33mDelta

Wed 5/286:05 pmSTL - PDX

1 stop7h 20mDelta

Deal found 3/24

$251

Fri 5/2311:59 pmPDX - STL

1 stop8h 13mUnited Airlines

Sun 5/255:00 amSTL - PDX

1 stop6h 42mUnited Airlines

Deal found 3/24

$262

Thu 4/36:40 amPDX - STL

1 stop24h 26mFrontier

Sun 4/61:06 pmSTL - PDX

1 stop21h 41mFrontier

Deal found 3/24

$300

Tue 4/2910:47 amPDX - STL

2 stops11h 12mAlaska Airlines

Wed 5/76:30 amSTL - PDX

1 stop6h 22mAlaska Airlines

Deal found 3/24

$318

Thu 5/11:30 pmPDX - STL

2 stops9h 20mSouthwest

Sun 5/47:30 pmSTL - PDX

1 stop7h 05mSouthwest

Deal found 3/24

$320

Thu 5/156:30 pmPDX - STL

1 stop15h 07mMultiple Airlines

Mon 5/196:53 pmSTL - PDX

1 stop7h 45mMultiple Airlines

Deal found 3/24

$331

Thu 6/2611:59 pmPDX - STL

1 stop9h 37mSun Country Air

Sun 6/296:00 amSTL - PDX

1 stop18h 46mSun Country Air

Deal found 3/23

$355

Sat 4/267:01 pmPDX - STL

2 stops20h 14mSpirit Airlines

Sat 5/1710:10 amSTL - PDX

2 stops32h 35mSpirit Airlines

Deal found 3/24

$562

Last-minute flights from Portland to St. Louis
Discover last-minute flight deals from Portland to St. Louis. Data last updated March 25, 2025 and is based on user searches.

Tue 4/112:59 amPDX - STL

1 stop7h 35mDelta

Tue 4/85:00 pmSTL - PDX

1 stop8h 44mDelta

Deal found 3/24

$313

Wed 4/210:01 pmPDX - STL

1 stop8h 08mAmerican Airlines

Tue 4/87:04 amSTL - PDX

1 stop7h 55mAmerican Airlines

Deal found 3/24

$303

Wed 4/25:00 amPDX - STL

2 stops10h 23mUnited Airlines

Tue 4/86:30 amSTL - PDX

1 stop7h 22mUnited Airlines

Deal found 3/24

$408

Thu 4/36:40 amPDX - STL

1 stop24h 26mFrontier

Mon 4/76:51 pmSTL - PDX

1 stop7h 46mFrontier

Deal found 3/24

$300

Thu 4/36:50 pmPDX - STL

2 stops14h 44mMultiple Airlines

Sun 4/66:35 amSTL - PDX

2 stops29h 45mMultiple Airlines

Deal found 3/24

$491

Thu 4/36:40 amPDX - STL

1 stop24h 26mFrontier

Sun 4/61:06 pmSTL - PDX

1 stop21h 41mFrontier

Deal found 3/24

$300

Fri 4/187:50 pmPDX - STL

2 stops12h 53mDelta

Tue 4/225:00 pmSTL - PDX

1 stop8h 44mDelta

Deal found 3/24

$270

Mon 4/215:20 amPDX - STL

2 stops11h 10mSouthwest

Fri 4/2510:10 amSTL - PDX

2 stops10h 00mSouthwest

Deal found 3/24

$529

Fri 4/252:58 pmPDX - STL

1 stop6h 35mAmerican Airlines

Mon 4/286:20 pmSTL - PDX

1 stop7h 42mAmerican Airlines

Deal found 3/24

$227

Fri 4/252:32 pmPDX - STL

2 stops18h 50mMultiple Airlines

Mon 4/288:15 amSTL - PDX

2 stops35h 50mMultiple Airlines

Deal found 3/24

$438

Sat 4/265:00 amPDX - STL

1 stop5h 47mUnited Airlines

Sat 5/174:50 pmSTL - PDX

1 stop8h 14mUnited Airlines

Deal found 3/24

$306

Sat 4/267:01 pmPDX - STL

2 stops20h 14mSpirit Airlines

Sat 5/1710:10 amSTL - PDX

2 stops32h 35mSpirit Airlines

Deal found 3/24

$562

One-way flights from Portland to St. Louis
Search for one-way flight options from Portland to St. Louis. Find affordable one-way fares based on user searches. Data last updated March 25, 2025.

Sat 5/176:00 amPDX - STL

1 stop9h 09mUnited Airlines

Deal found 3/24

$109

Tue 5/201:25 pmPDX - STL

1 stop8h 39mAlaska Airlines

Deal found 3/24

$111

Sat 4/125:31 amPDX - STL

1 stop7h 42mAmerican Airlines

Deal found 3/24

$112

Fri 5/212:59 amPDX - STL

1 stop7h 42mDelta

Deal found 3/24

$114

Wed 5/71:35 pmPDX - STL

2 stops17h 40mSpirit Airlines

Deal found 3/24

$126

Thu 4/106:40 amPDX - STL

1 stop24h 26mFrontier

Deal found 3/24

$156

Tue 5/67:01 pmPDX - STL

3 stops47h 09mMultiple Airlines

Deal found 3/24

$163

Mon 6/99:15 pmPDX - STL

1 stop8h 35mSouthwest

Deal found 3/24

$185

Cheapflights Fare Finder

Use the filters below to find and compare flights from Portland to St. Louis that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

PortlandSt. Louis

PDX - STL

PDXSTL

Portland

Thu 5/1

12:03 pm-11:16 pm

1 stop9h 13m

Lambert-St Louis

Fri 5/2

6:20 pm-12:02 am

1 stop7h 42m

$227

PortlandSt. Louis

PDX - STL

PDXSTL

Portland

Wed 5/14

5:00 pm-12:33 am

1 stop5h 33m

Lambert-St Louis

Wed 5/28

6:05 pm-11:25 pm

1 stop7h 20m

$251

PortlandSt. Louis

PDX - STL

PDXSTL

Portland

Fri 5/23

11:59 pm-10:12 am

1 stop8h 13m

Lambert-St Louis

Sun 5/25

5:00 am-9:42 am

1 stop6h 42m

$262

PortlandSt. Louis

PDX - STL

PDXSTL

Portland

Thu 4/3

6:40 am-9:06 am

1 stop24h 26m

Lambert-St Louis

Mon 4/7

6:51 pm-12:37 am

1 stop7h 46m

$300

PortlandSt. Louis

PDX - STL

PDXSTL

Portland

Tue 4/29

10:47 am-11:59 pm

2 stops11h 12m

Lambert-St Louis

Wed 5/7

6:30 am-10:52 am

1 stop6h 22m

$318

PortlandSt. Louis

PDX - STL

PDXSTL

Portland

Thu 5/1

1:30 pm-12:50 am

2 stops9h 20m

Lambert-St Louis

Sun 5/4

7:30 pm-12:35 am

1 stop7h 05m

$320

PortlandSt. Louis

PDX - STL

PDXSTL

Portland

Thu 5/15

6:30 pm-11:37 am

1 stop15h 07m

Lambert-St Louis

Mon 5/19

6:53 pm-12:38 am

1 stop7h 45m

$331

PortlandSt. Louis

PDX - STL

PDXSTL

Portland

Thu 6/26

11:59 pm-11:36 am

1 stop9h 37m

Lambert-St Louis

Sun 6/29

6:00 am-10:46 pm

1 stop18h 46m

$355

PortlandSt. Louis

PDX - STL

PDXSTL

Portland

Sat 4/26

7:01 pm-5:15 pm

2 stops20h 14m

Lambert-St Louis

Sat 5/17

10:10 am-4:45 pm

2 stops32h 35m

$562

PortlandSt. Louis

PDX - STL

PDXSTL

Portland

Sat 5/17

6:00 am-5:09 pm

1 stop9h 09m

$109

Flights are sorted by cheapest round-trip flights first.

Deals found on 3/24

Showing 1-10 of 17 results

Compare providers for flights from Portland to St. Louis

Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Portland to St. Louis in March.

Provider	Price Accuracy	Trust Score*
Expedia	Price Accuracy1 star	Trust Score*3 stars
FlightHub	Price Accuracy3 stars	Trust Score*3 stars
eDreams	Price Accuracy3 stars	Trust Score*3 stars
CheapOair	Price Accuracy1 star	Trust Score*3 stars
CheapTicketsDeal	Price Accuracy3 stars	Trust Score*3 stars
Priceline	Price Accuracy1 star	Trust Score*3 stars

*The Trust Score is based on feedback from users after their booking experience. It measures overall satisfaction, helping us identify issues like hidden fees, problems during the ticketing process, and the quality of customer service. This score is our best indicator of the provider's quality and reliability.

Most accurate provider: When it comes to deals on Portland-St. Louis flights, users find the pricing of FlightHub to be most consistent on Cheapflights vs. FlightHub Users can find the same prices on Portland-St. Louis flight deals on Cheapflights vs. FlightHub >95% of the time. Price accuracy is based on data collected from Portland-St. Louis flight searches over the past month and is updated monthly.
Most trusted provider: When it comes to deals on Portland-St. Louis flights, Cheapflights users trust FlightHub the most. FlightHub has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Portland-St. Louis flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.

Best time to book a flight from Portland to St. Louis

Have a flexible travel schedule? Discover the best time to fly to St. Louis from Portland with our price prediction graph.

Estimated round-trip price

Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Portland to St. Louis

How far ahead should I book a flight from Portland to St. Louis?

The best time to book flights from Portland to St. Louis is 89 days before your desired departure date. The cost of your flight will likely increase significantly if you book two weeks in advance of your flight.

What is the cheapest month to book a flight from Portland to St. Louis?

Currently, August is the cheapest month in which you can book a flight from Portland to St. Louis (average of $311). Flying from Portland to St. Louis in March is currently the most expensive (average of $356). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from PDX to STL?

Unlike in the morning, when flights are generally more expensive, you can save up to 31% on flights from Portland to St. Louis by exploring options for tickets in the afternoon.

What is the cheapest day to fly from Portland to St. Louis?

Travelers seeking maximum savings on their Portland to St. Louis flight should consider departing on Thursday evenings when fares are most often at their lowest. Saturday afternoons flights should be avoided if possible as fares are typically the most expensive at this time.

Rainfall in St. Louis by month

In terms of precipitation, rainfall in St. Louis ranges from 2.2 - 4.7 inches per month. May is typically the wettest month, when rainfall can reach 4.7 in. February is typically the driest time to visit St. Louis when rainfall is around 2.2 in.

Temperature in St. Louis by month

If weather is an important factor for your trip to St. Louis, use this chart to help with planning. For those seeking warmer temperatures, July is the ideal time of year to visit, when temperatures reach an average of 80.6 F. Travelers looking to avoid the cold should look outside of January, when temperatures are typically at their lowest (around 32.0 F).

Reviews of airlines servicing St. Louis

Read through reviews of airlines operating flights from Portland to St. Louis, such as Alaska Airlines, Southwest and Delta. Reviews also offer insight into each airline's entertainment options, comfort, food, crew/service, and boarding process.

Alaska Airlines

8.0

Very good

9,782 reviews

Reviews

1 / 20

10.0

Excellent

Cheri,Jan 2025

FAT - SEA

Very friendly. I really liked that they had water for us in cartons not plastic. Impressed with Alaska Airlines, First time I had flown them

Alaska Airlines

8.0

Very good

9,782 reviews

Alaska Airlines

8.0

Very good

9,782 reviews

Reviews

1 / 20

10.0

Excellent

Cheri,Jan 2025

FAT - SEA

Very friendly. I really liked that they had water for us in cartons not plastic. Impressed with Alaska Airlines, First time I had flown them

Southwest

8.0

Very good

4,272 reviews

Alaska Airlines

8.0

Very good

9,782 reviews

Reviews

1 / 20

10.0

Excellent

Cheri,Jan 2025

FAT - SEA

Very friendly. I really liked that they had water for us in cartons not plastic. Impressed with Alaska Airlines, First time I had flown them

Delta

8.0

Very good

7,890 reviews

Alaska Airlines

8.0

Very good

9,782 reviews

Reviews

1 / 20

10.0

Excellent

Cheri,Jan 2025

FAT - SEA

Very friendly. I really liked that they had water for us in cartons not plastic. Impressed with Alaska Airlines, First time I had flown them

United Airlines

7.4

Good

8,605 reviews

Alaska Airlines

8.0

Very good

9,782 reviews

Reviews

1 / 20

10.0

Excellent

Cheri,Jan 2025

FAT - SEA

Very friendly. I really liked that they had water for us in cartons not plastic. Impressed with Alaska Airlines, First time I had flown them

American Airlines

7.2

Good

10,000 reviews

Alaska Airlines

8.0

Very good

9,782 reviews

Reviews

1 / 20

10.0

Excellent

Cheri,Jan 2025

FAT - SEA

Very friendly. I really liked that they had water for us in cartons not plastic. Impressed with Alaska Airlines, First time I had flown them

Related info for your journey

What are the cheapest airlines flying from Portland to St. Louis round-trip?
Currently priced at $227, American Airlines will fly you from Portland to St. Louis and back. In addition to American Airlines, many other airlines offer competitively priced options for your trip. Search Cheapflights for deals from Delta and United Airlines - these airlines can fly you to your destination from $251 and $262, respectively. Users have found that American Airlines is 41% cheaper than the other options available to this destination.
What are the cheapest airlines to fly from Portland to St. Louis one-way?
To fly one-way, consider booking your trip with United Airlines, which is currently one of the cheapest options available, starting at $109. Alaska Airlines flights start at $111 while deals on American Airlines start at $112 one-way.
What are the cheapest flights from Portland to St. Louis?
Looking at all options, your cheapest flight can be booked for $209. While the most popular route (Portland - Lambert-St Louis) can be booked for $227 on average our data indicates $209 when flying from Portland to St. Louis.
Where are the most common layover locations when flying from Portland to St. Louis?
Portland to St. Louis flights have a layover in Salt Lake City most of the time.
What are some popular things to do or see while on a layover in Salt Lake City?
If you're on a layover in Salt Lake City and looking for things to do, consider visiting Temple Square, Abravanel Hall, or Salt Lake Temple. Temple Square, Abravanel Hall, and Salt Lake Temple are located about 4.7 mi, 4.7 mi, and 4.8 mi, respectively from Salt Lake City. Travelers can rent a car at Salt Lake City for an average daily rate of $55 to make sightseeing during their layover a little easier.
Where are the least popular layover locations for Portland to St. Louis flights?
Of the flights from Portland to St. Louis that have layovers, the fewest flights stop in Denver.
Can I find deals for flights from Portland to St. Louis that include hotel bookings?
Yes. In addition to deals on Portland to St. Louis flights, Cheapflights offers vacation packages that include both flights and hotel.
How can I find direct flights from Portland to St. Louis?
After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Portland to St. Louis.
Can I find deals for business class flights from Portland to St. Louis?
Yes. Cheapflights offers flight deals from Portland to St. Louis by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.
What is the cheapest month to book a flight from Portland to St. Louis?
Currently, August is the cheapest month in which you can book a flight from Portland to St. Louis (average of $311). Flying from Portland to St. Louis in March is currently the most expensive (average of $356). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

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Other flights to St. Louis

Top 6 airlines flying from Portland to St. Louis

Airline	Cheapest	Average	Flexibility	On-time
Frontier	Cheapest$110	Average$204	FlexibilityNo cancel fee	On-time62%
American Airlines	Cheapest$197	Average$398	FlexibilityNo cancel fee	On-time71%
Delta	Cheapest$215	Average$385	FlexibilityNo cancel fee	On-timeN/A
Alaska Airlines	Cheapest$228	Average$440	FlexibilityNo cancel fee	On-time75%
United Airlines	Cheapest$255	Average$459	FlexibilityNo cancel fee	On-time69%
Southwest	Cheapest$333	Average$515	FlexibilityNo cancel fee	On-time63%

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$109+ Cheap flights from Portland to St. Louis (PDX - STL)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 5/17. Fares are subject to change and may not be available on all flights or dates of travel.

Find cheap flights from Portland to St. Louis with Cheapflights

1. Tell us where you want to go

2. Select your favorite providers

3. Compare prices and book

Cheapflights Tip: The best prices from Portland to Lambert-St Louis are usually found in January or September, booked 89 days in advance, depart on a Thursday or Monday and return on a Tuesday

Cheap flight deals from Portland to St. Louis

Most accurate provider

Most trusted provider

Round-trip from

One-way from

Popular in

Cheapest in

Average price

Good one-way deal

Find flight deals from Portland to St. Louis

Cheapest flights from Portland to St. LouisExplore the most affordable flight options available from Portland to St. Louis. Find the lowest fares from popular airlines and budget airlines, with prices last updated on March 25, 2025.

Explore the most affordable flight options available from Portland to St. Louis. Find the lowest fares from popular airlines and budget airlines, with prices last updated on March 25, 2025.

Cheapflights Fare Finder

Use the filters below to find and compare flights from Portland to St. Louis that are best for you.

Compare providers for flights from Portland to St. Louis

Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.

Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Portland to St. Louis in March.

Best time to book a flight from Portland to St. Louis

Have a flexible travel schedule? Discover the best time to fly to St. Louis from Portland with our price prediction graph.

Cheapflights Insights

Everything you need to know about your flight from Portland to St. Louis

How far ahead should I book a flight from Portland to St. Louis?

Use this chart to determine the optimal time to book a round-trip flight from Portland to St. Louis. Price data was last updated on March 21, 2025.

What is the cheapest month to book a flight from Portland to St. Louis?

What is the cheapest time of day to fly from PDX to STL?

Find hourly flight availability from Portland to St. Louis. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated March 25, 2025.

What is the cheapest day to fly from Portland to St. Louis?

Use this chart to determine the cheapest time to fly round-trip from Portland to St. Louis. Price data was last updated on March 23, 2025.

Rainfall in St. Louis by month

Plan your trip to St. Louis by taking into account the average rainfall totals by month.

Temperature in St. Louis by month

Plan your trip to St. Louis by taking into account the average temperature totals by month.

Reviews of airlines servicing St. Louis

Read through reviews of airlines operating flights from Portland to St. Louis, such as Alaska Airlines, Southwest and Delta. Reviews also offer insight into each airline's entertainment options, comfort, food, crew/service, and boarding process.

Related info for your journey

Find useful and relevant information for your journey from Portland to St. Louis. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

What are the cheapest airlines flying from Portland to St. Louis round-trip?

What are the cheapest airlines to fly from Portland to St. Louis one-way?

What are the cheapest flights from Portland to St. Louis?

Where are the most common layover locations when flying from Portland to St. Louis?

What are some popular things to do or see while on a layover in Salt Lake City?

Where are the least popular layover locations for Portland to St. Louis flights?

Can I find deals for flights from Portland to St. Louis that include hotel bookings?

How can I find direct flights from Portland to St. Louis?

Can I find deals for business class flights from Portland to St. Louis?

What is the cheapest month to book a flight from Portland to St. Louis?

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Alternative routes for Portland to St. Louis

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Top 6 airlines flying from Portland to St. Louis

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Cheapest flights from Portland to St. Louis
Explore the most affordable flight options available from Portland to St. Louis. Find the lowest fares from popular airlines and budget airlines, with prices last updated on March 25, 2025.