What are the cheapest airlines flying from Panama City to St. Louis round-trip?

Our cheapest airline available from Panama City to St. Louis is United Airlines. Our recent data shows that you can find tickets from as low as $483 on this airline. An additional option worth looking into is American Airlines, starting at $497. You may be able to fly from Panama City to St. Louis for 17% less than the average price by searching for these airlines.

What are the cheapest airlines to fly from Panama City to St. Louis one-way?

The cheapest airlines for a one-way flight from Panama City to St. Louis are Delta ($323), American Airlines ($332), and United Airlines ($349).

What is the cheapest day to fly from Panama City to St. Louis?

Travelers seeking maximum savings on their Panama City to St. Louis flight should consider departing on Sunday afternoons when fares are most often at their lowest. Wednesday afternoons flights should be avoided if possible as fares are typically the most expensive at this time.

What is the cheapest day to fly round-trip from Panama City to St. Louis?

It’s generally more expensive to depart on a Wednesday, if you have to leave on this day you can still search on Cheapflights to find great options that meet your needs.

What is the cheapest month to fly from Panama City to St. Louis?

October can be a great time to fly to St. Louis from Panama City with a flight ticket averaging about $588. Cheapflights users have found deals in the month of October for as cheap as $485. The most expensive prices can be found in the month of February.

Most accurate provider : When it comes to deals on Panama City-St. Louis flights, users find the pricing of FlightHub to be most consistent on Cheapflights vs. FlightHub Users can find the same prices on Panama City-St. Louis flight deals on Cheapflights vs. FlightHub >95% of the time. Price accuracy is based on data collected from Panama City-St. Louis flight searches over the past month and is updated monthly.

Most trusted provider : When it comes to deals on Panama City-St. Louis flights, Cheapflights users trust FlightHub the most. FlightHub has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Panama City-St. Louis flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.

Can I find deals for flights from Panama City to St. Louis that include hotel bookings?

Yes. In addition to deals on Panama City to St. Louis flights, Cheapflights offers vacation packages that include both flights and hotel.

How can I find direct flights from Panama City to St. Louis?

After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Panama City to St. Louis.

Can I find deals for business class flights from Panama City to St. Louis?

Yes. Cheapflights offers flight deals from Panama City to St. Louis by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

$277+ Flights from Panama City to St. Louis

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1. Tell us where you want to go

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Cheap flight deals from Panama City to St. Louis

Most accurate provider	FlightHub 3 stars
Most trusted provider	FlightHub 3 stars
Round-trip from	$483 (United Airlines)
One-way from	$277 (Kiwi.com)
Popular in	February
Cheapest in	October
Average price	$642

Provider with most accurate pricing for Panama City Tocumen Intl-Lambert-St Louis flight deals.

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Provider most trusted by Cheapflights users for Panama City Tocumen Intl-Lambert-St Louis flights.

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From Panama City Tocumen Intl to Lambert-St Louis

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One-way flight from Panama City Tocumen Intl to Lambert-St Louis

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High demand for flights, 11% potential price rise

Search Deals

Best time to find cheap flights, 1% potential price drop

Search Deals

Average for round-trip flights in January 2025

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Find flight deals from Panama City to St. Louis

Cheapest flights from Panama City to St. Louis
Explore the most affordable flight options available from Panama City to St. Louis. Find the lowest fares from popular airlines and budget airlines, with prices last updated on enero 17, 2025.

mar. 5/67:55 amPTY - STL

2 stops13h 53mUnited Airlines

mar. 5/138:50 amSTL - PTY

1 stop7h 22mUnited Airlines

Deal found 1/16

$483

mié. 5/211:50 pmPTY - STL

2 stops20h 22mAmerican Airlines

mié. 6/45:50 pmSTL - PTY

2 stops18h 34mAmerican Airlines

Deal found 1/16

$497

mar. 5/61:30 pmPTY - STL

3 stops20h 18mMultiple Airlines

mar. 5/131:30 pmSTL - PTY

2 stops20h 40mMultiple Airlines

Deal found 1/16

$1,294

Best flights from Panama City to St. Louis
Discover carefully curated flight deals from Panama City to St. Louis that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated enero 17, 2025.

mar. 5/67:55 amPTY - STL

2 stops13h 53mUnited Airlines

mar. 5/138:50 amSTL - PTY

1 stop7h 22mUnited Airlines

Deal found 1/16

$483

mié. 5/211:50 pmPTY - STL

1 stop9h 13mAmerican Airlines

mié. 6/45:20 pmSTL - PTY

2 stops20h 55mAmerican Airlines

Deal found 1/16

$497

mar. 5/61:30 pmPTY - STL

3 stops20h 18mMultiple Airlines

mar. 5/131:30 pmSTL - PTY

2 stops20h 40mMultiple Airlines

Deal found 1/16

$1,294

One-way flights from Panama City to St. Louis
Search for one-way flight options from Panama City to St. Louis. Find affordable one-way fares based on user searches. Data last updated enero 17, 2025.

vie. 1/313:19 amPTY - STL

2 stops36h 24mMultiple Airlines

Deal found 1/15

$277

sáb. 3/88:05 amPTY - STL

1 stop8h 29mDelta

Deal found 1/15

$323

sáb. 3/14:40 pmPTY - STL

2 stops18h 53mAmerican Airlines

Deal found 1/16

$332

sáb. 3/14:40 pmPTY - STL

1 stop18h 11mUnited Airlines

Deal found 1/16

$349

sáb. 3/81:30 pmPTY - STL

3 stops20h 38mAvianca

Deal found 1/15

$1,710

Find flights from Panama City to St. Louis within your budget

Fly from

Fly to

Route

Depart

Return

Price

Panama CitySt. Louis

PTY - STL

PTYSTL

Panama City Tocumen Intl

mar. 5/6

7:55 am-9:48 pm

2 stops13h 53m

Lambert-St Louis

mar. 5/13

8:50 am-4:12 pm

1 stop7h 22m

$483

Panama CitySt. Louis

PTY - STL

PTYSTL

Panama City Tocumen Intl

mié. 5/21

1:50 pm-10:12 am

2 stops20h 22m

Lambert-St Louis

mié. 6/4

5:50 pm-12:24 pm

2 stops18h 34m

$497

Panama CitySt. Louis

PTY - STL

PTYSTL

Panama City Tocumen Intl

mar. 5/6

1:30 pm-9:48 am

3 stops20h 18m

Lambert-St Louis

mar. 5/13

1:30 pm-10:10 am

2 stops20h 40m

$1,294

Panama CitySt. Louis

PTY - STL

PTYSTL

Panama City Tocumen Intl

vie. 1/31

3:19 am-2:43 pm

2 stops36h 24m

$277

Panama CitySt. Louis

PTY - STL

PTYSTL

Panama City Tocumen Intl

sáb. 3/8

8:05 am-3:34 pm

1 stop8h 29m

$323

Panama CitySt. Louis

PTY - STL

PTYSTL

Panama City Tocumen Intl

sáb. 3/1

4:40 pm-10:33 am

2 stops18h 53m

$332

Panama CitySt. Louis

PTY - STL

PTYSTL

Panama City Tocumen Intl

sáb. 3/1

4:40 pm-9:51 am

1 stop18h 11m

$349

Panama CitySt. Louis

PTY - STL

PTYSTL

Panama City Tocumen Intl

sáb. 3/8

1:30 pm-9:08 am

3 stops20h 38m

$1,710

Flights are sorted by cheapest round-trip flights first.

Deals found on 1/15

Compare providers for flights from Panama City to St. Louis

Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Panama City to St. Louis in January.

Provider	Price Accuracy	Trust Score*
eDreams	Price Accuracy3 stars	Trust Score*3 stars
FlightHub	Price Accuracy3 stars	Trust Score*3 stars
AranGrant	Price Accuracy3 stars	Trust Score*3 stars

*The Trust Score is based on feedback from users after their booking experience. It measures overall satisfaction, helping us identify issues like hidden fees, problems during the ticketing process, and the quality of customer service. This score is our best indicator of the provider's quality and reliability.

Most accurate provider: When it comes to deals on Panama City-St. Louis flights, users find the pricing of FlightHub to be most consistent on Cheapflights vs. FlightHub Users can find the same prices on Panama City-St. Louis flight deals on Cheapflights vs. FlightHub >95% of the time. Price accuracy is based on data collected from Panama City-St. Louis flight searches over the past month and is updated monthly.
Most trusted provider: When it comes to deals on Panama City-St. Louis flights, Cheapflights users trust FlightHub the most. FlightHub has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Panama City-St. Louis flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.

Best time to book a flight from Panama City to St. Louis

Have a flexible travel schedule? Discover the best time to fly to St. Louis from Panama City with our price prediction graph.

Estimated round-trip price

Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Travel insights for flights from Panama City to St. Louis

Get recent, data-driven insights about flights from Panama City to St. Louis including ideal travel times, pricing trends, and more.

What is the cheapest month to book a flight from Panama City to St. Louis?

Currently, August is the cheapest month in which you can book a flight from Panama City to St. Louis (average of $311). Flying from Panama City to St. Louis in March is currently the most expensive (average of $356). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from PTY to STL?

When flying from Panama City to St. Louis, the time of day you fly usually plays a role in the price. Save by searching for a flight at noon, which can drop the price by up to 7% versus a flight in the morning.

Rainfall in St. Louis by month

In terms of precipitation, rainfall in St. Louis ranges from 2.2 - 4.7 inches per month. May is typically the wettest month, when rainfall can reach 4.7 in. February is typically the driest time to visit St. Louis when rainfall is around 2.2 in.

Temperature in St. Louis by month

If weather is an important factor for your trip to St. Louis, use this chart to help with planning. For those seeking warmer temperatures, July is the ideal time of year to visit, when temperatures reach an average of 80.6 F. Travelers looking to avoid the cold should look outside of January, when temperatures are typically at their lowest (around 32.0 F).

Reviews of airlines servicing St. Louis

Delta

8.0

Very good

8,511 reviews

Reviews

1 / 10

Delta has consistently been the best U.S. airline for my travels and this flight was no exception

Delta

8.0

Very good

8,511 reviews

Delta

8.0

Very good

8,511 reviews

Reviews

1 / 10

Delta has consistently been the best U.S. airline for my travels and this flight was no exception

United Airlines

7.4

Good

8,965 reviews

Delta

8.0

Very good

8,511 reviews

Reviews

1 / 10

Delta has consistently been the best U.S. airline for my travels and this flight was no exception

American Airlines

7.2

Good

10,000 reviews

Delta

8.0

Very good

8,511 reviews

Reviews

1 / 10

Delta has consistently been the best U.S. airline for my travels and this flight was no exception

Avianca

6.9

Okay

2,573 reviews

Delta

8.0

Very good

8,511 reviews

Reviews

1 / 10

Delta has consistently been the best U.S. airline for my travels and this flight was no exception

Related info for your journey

What are the cheapest airlines flying from Panama City to St. Louis round-trip?
Our cheapest airline available from Panama City to St. Louis is United Airlines. Our recent data shows that you can find tickets from as low as $483 on this airline. An additional option worth looking into is American Airlines, starting at $497. You may be able to fly from Panama City to St. Louis for 17% less than the average price by searching for these airlines.
What are the cheapest airlines to fly from Panama City to St. Louis one-way?
The cheapest airlines for a one-way flight from Panama City to St. Louis are Delta ($323), American Airlines ($332), and United Airlines ($349).
Can I find deals for flights from Panama City to St. Louis that include hotel bookings?
Yes. In addition to deals on Panama City to St. Louis flights, Cheapflights offers vacation packages that include both flights and hotel.
How can I find direct flights from Panama City to St. Louis?
After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Panama City to St. Louis.
Can I find deals for business class flights from Panama City to St. Louis?
Yes. Cheapflights offers flight deals from Panama City to St. Louis by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.
What is the cheapest month to book a flight from Panama City to St. Louis?
Currently, August is the cheapest month in which you can book a flight from Panama City to St. Louis (average of $311). Flying from Panama City to St. Louis in March is currently the most expensive (average of $356). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Fenton

Fairview Heights

Maryland Heights

Collinsville

Wentzville

Eureka

St. Peters

Festus

Alton

Farmington

Chesterfield

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Top 2 airlines flying from Panama City to St. Louis

Airline	Cheapest	Average	Flexibility	On-time
Delta	Cheapest$354	Average$601	FlexibilityNo cancel fee	On-timeN/A
United Airlines	Cheapest$386	Average$567	FlexibilityNo cancel fee	On-time69%

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$277+ Cheap flights from Panama City (PTY) to St. Louis (STL)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 1/31. Fares are subject to change and may not be available on all flights or dates of travel.

Find cheap flights from Panama City to St. Louis with Cheapflights

1. Tell us where you want to go

2. Select your favorite providers

3. Compare prices and book

Cheap flight deals from Panama City to St. Louis

Most accurate provider

Most trusted provider

Round-trip from

One-way from

Popular in

Cheapest in

Average price

Find flight deals from Panama City to St. Louis

Cheapest flights from Panama City to St. LouisExplore the most affordable flight options available from Panama City to St. Louis. Find the lowest fares from popular airlines and budget airlines, with prices last updated on enero 17, 2025.

Explore the most affordable flight options available from Panama City to St. Louis. Find the lowest fares from popular airlines and budget airlines, with prices last updated on enero 17, 2025.

Find flights from Panama City to St. Louis within your budget

Compare providers for flights from Panama City to St. Louis

Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.

Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Panama City to St. Louis in January.

Best time to book a flight from Panama City to St. Louis

Have a flexible travel schedule? Discover the best time to fly to St. Louis from Panama City with our price prediction graph.

Travel insights for flights from Panama City to St. Louis

Get recent, data-driven insights about flights from Panama City to St. Louis including ideal travel times, pricing trends, and more.

What is the cheapest month to book a flight from Panama City to St. Louis?

What is the cheapest time of day to fly from PTY to STL?

Find hourly flight availability from Panama City to St. Louis. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated enero 17, 2025.

Rainfall in St. Louis by month

Plan your trip to St. Louis by taking into account the average rainfall totals by month.

Temperature in St. Louis by month

Plan your trip to St. Louis by taking into account the average temperature totals by month.

Reviews of airlines servicing St. Louis

Related info for your journey

Find useful and relevant information for your journey from Panama City to St. Louis. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

What are the cheapest airlines flying from Panama City to St. Louis round-trip?

What are the cheapest airlines to fly from Panama City to St. Louis one-way?

Can I find deals for flights from Panama City to St. Louis that include hotel bookings?

How can I find direct flights from Panama City to St. Louis?

Can I find deals for business class flights from Panama City to St. Louis?

What is the cheapest month to book a flight from Panama City to St. Louis?

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Alternative routes for Panama City to St. Louis

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Top 2 airlines flying from Panama City to St. Louis

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Cheapest flights from Panama City to St. Louis
Explore the most affordable flight options available from Panama City to St. Louis. Find the lowest fares from popular airlines and budget airlines, with prices last updated on enero 17, 2025.