What are the cheapest airlines flying from Panama City to St. Louis round-trip?

Our cheapest airline available from Panama City to St. Louis is American Airlines. Our recent data shows that you can find tickets from as low as $495 on this airline. Additional options worth looking into are United Airlines and Avianca, starting at $514 and $2,140 round-trip. You may be able to fly from Panama City to St. Louis for 14% less than the average price by searching for these airlines.

What is the cheapest day to fly from Panama City to St. Louis?

Travelers seeking maximum savings on their Panama City to St. Louis flight should consider departing on Sunday afternoons when fares are most often at their lowest. Wednesday afternoons flights should be avoided if possible as fares are typically the most expensive at this time.

What is the cheapest day to fly round-trip from Panama City to St. Louis?

It’s generally more expensive to depart on a Wednesday, if you have to leave on this day you can still search on Cheapflights to find great options that meet your needs.

What is the cheapest month to fly from Panama City to St. Louis?

November can be a great time to fly to St. Louis from Panama City with a flight ticket averaging about $581. Cheapflights users have found deals in the month of November for as cheap as $252. The most expensive prices can be found in the month of March.

Most accurate provider : When it comes to deals on Panama City-St. Louis flights, users find the pricing of FlightHub to be most consistent on Cheapflights vs. FlightHub Users can find the same prices on Panama City-St. Louis flight deals on Cheapflights vs. FlightHub >95% of the time. Price accuracy is based on data collected from Panama City-St. Louis flight searches over the past month and is updated monthly.

Most trusted provider : When it comes to deals on Panama City-St. Louis flights, Cheapflights users trust FlightHub the most. FlightHub has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Panama City-St. Louis flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.

Can I find deals for flights from Panama City to St. Louis that include hotel bookings?

Yes. In addition to deals on Panama City to St. Louis flights, Cheapflights offers vacation packages that include both flights and hotel.

How can I find direct flights from Panama City to St. Louis?

After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Panama City to St. Louis.

Can I find deals for business class flights from Panama City to St. Louis?

Yes. Cheapflights offers flight deals from Panama City to St. Louis by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

$295+ Flights from Panama City, Panama to St. Louis, Missouri

Home Search by date Vacation packages Hotels Flight deals Car rental Travel tips & news

Find cheap flights from Panama City to St. Louis with Cheapflights

1. Tell us where you want to go

Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”

2. Select your favorite providers

We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.

3. Compare prices and book

Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.

Cheap flight deals from Panama City to St. Louis

Most accurate provider	FlightHub 3 stars
Most trusted provider	FlightHub 3 stars
Popular in	March
Cheapest in	November
Round-trip from	$495 (American Airlines)
One-way from	$295 (Delta)

Provider with most accurate pricing for Panama City Tocumen Intl-Lambert-St Louis flight deals.

Search Deals

Provider most trusted by Cheapflights users for Panama City Tocumen Intl-Lambert-St Louis flights.

Search Deals

High demand for flights, 14% potential price rise

Search Deals

Best time to find cheap flights, 13% potential price drop

Search Deals

From Panama City Tocumen Intl to Lambert-St Louis

Search Deals

One-way flight from Panama City Tocumen Intl to Lambert-St Louis

Search Deals

Find flight deals from Panama City to St. Louis

Best flights from Panama City to St. Louis
Discover carefully curated flight deals from Panama City to St. Louis that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated November 20, 2024.

Tue 1/142:35 pmPTY - STL

2 stops20h 49mAmerican Airlines

Tue 2/116:29 pmSTL - PTY

2 stops20h 20mAmerican Airlines

Deal found 11/18

$495

Tue 1/144:40 pmPTY - STL

2 stops20h 36mUnited Airlines

Tue 2/1110:55 amSTL - PTY

1 stop7h 43mUnited Airlines

Deal found 11/18

$514

Mon 1/133:19 amPTY - STL

3 stops33h 11mMultiple Airlines

Tue 2/113:48 pmSTL - PTY

2 stops21h 52mMultiple Airlines

Deal found 11/18

$777

Tue 1/141:30 pmPTY - STL

3 stops21h 54mAvianca

Tue 2/118:15 amSTL - PTY

2 stops15h 05mAvianca

Deal found 11/18

$2,140

One-way flights from Panama City to St. Louis
Search for one-way flight options from Panama City to St. Louis. Find affordable one-way fares based on user searches. Data last updated November 20, 2024.

Wed 1/153:27 pmPTY - STL

1 stop9h 10mDelta

Deal found 11/20

$295

Wed 1/154:40 pmPTY - STL

2 stops21h 41mAmerican Airlines

Deal found 11/19

$304

Tue 1/143:19 amPTY - STL

2 stops13h 19mMultiple Airlines

Deal found 11/20

$447

Find flights from Panama City to St. Louis within your budget

Fly from

Fly to

Route

Depart

Return

Price

Panama CitySt. Louis

PTY - STL

PTYSTL

Panama City Tocumen Intl

Tue 1/14

2:35 pm-10:24 am

2 stops20h 49m

Lambert-St Louis

Tue 2/11

6:29 pm-3:49 pm

2 stops20h 20m

$495

Panama CitySt. Louis

PTY - STL

PTYSTL

Panama City Tocumen Intl

Tue 1/14

4:40 pm-12:16 pm

2 stops20h 36m

Lambert-St Louis

Tue 2/11

10:55 am-7:38 pm

1 stop7h 43m

$514

Panama CitySt. Louis

PTY - STL

PTYSTL

Panama City Tocumen Intl

Mon 1/13

3:19 am-11:30 am

3 stops33h 11m

Lambert-St Louis

Tue 2/11

3:48 pm-2:40 pm

2 stops21h 52m

$777

Panama CitySt. Louis

PTY - STL

PTYSTL

Panama City Tocumen Intl

Tue 1/14

1:30 pm-10:24 am

3 stops21h 54m

Lambert-St Louis

Tue 2/11

8:15 am-12:20 am

2 stops15h 05m

$2,140

Panama CitySt. Louis

PTY - STL

PTYSTL

Panama City Tocumen Intl

Wed 1/15

3:27 pm-11:37 pm

1 stop9h 10m

$295

Panama CitySt. Louis

PTY - STL

PTYSTL

Panama City Tocumen Intl

Wed 1/15

4:40 pm-1:21 pm

2 stops21h 41m

$304

Panama CitySt. Louis

PTY - STL

PTYSTL

Panama City Tocumen Intl

Tue 1/14

3:19 am-3:38 pm

2 stops13h 19m

$447

Flights are sorted by cheapest round-trip flights first.

Deals found on 11/20

Compare providers for flights from Panama City to St. Louis

Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Panama City to St. Louis in November.

Provider	Price Accuracy	Trust Score*
eDreams	Price Accuracy3 stars	Trust Score*3 stars
FlightHub	Price Accuracy3 stars	Trust Score*3 stars
AranGrant	Price Accuracy3 stars	Trust Score*3 stars

*The Trust Score is based on feedback from users after their booking experience. It measures overall satisfaction, helping us identify issues like hidden fees, problems during the ticketing process, and the quality of customer service. This score is our best indicator of the provider's quality and reliability.

Most accurate provider: When it comes to deals on Panama City-St. Louis flights, users find the pricing of FlightHub to be most consistent on Cheapflights vs. FlightHub Users can find the same prices on Panama City-St. Louis flight deals on Cheapflights vs. FlightHub >95% of the time. Price accuracy is based on data collected from Panama City-St. Louis flight searches over the past month and is updated monthly.
Most trusted provider: When it comes to deals on Panama City-St. Louis flights, Cheapflights users trust FlightHub the most. FlightHub has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Panama City-St. Louis flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.

Best time to book a flight from Panama City to St. Louis

Have a flexible travel schedule? Discover the best time to fly to St. Louis from Panama City with our price prediction graph.

Estimated round-trip price

Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Travel insights for flights from Panama City to St. Louis

Get recent, data-driven insights about flights from Panama City to St. Louis including ideal travel times, pricing trends, and more.

What is the cheapest month to book a flight from Panama City to St. Louis?

Currently, September is the cheapest month in which you can book a flight from Panama City to St. Louis (average of $308). Flying from Panama City to St. Louis in March is currently the most expensive (average of $357). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from PTY to STL?

When flying from Panama City to St. Louis, the time of day you fly usually plays a role in the price. Save by searching for a flight at noon, which can drop the price by up to 10% versus a flight in the morning.

Rainfall in St. Louis by month

In terms of precipitation, rainfall in St. Louis ranges from 2.2 - 4.7 inches per month. May is typically the wettest month, when rainfall can reach 4.7 in. February is typically the driest time to visit St. Louis when rainfall is around 2.2 in.

Temperature in St. Louis by month

If weather is an important factor for your trip to St. Louis, use this chart to help with planning. For those seeking warmer temperatures, July is the ideal time of year to visit, when temperatures reach an average of 80.6 F. Travelers looking to avoid the cold should look outside of January, when temperatures are typically at their lowest (around 32.0 F).

Reviews of airlines servicing St. Louis

Delta

8.0

Very good

8,756 reviews

Reviews

1 / 10

Delta has consistently been the best U.S. airline for my travels and this flight was no exception

Delta

8.0

Very good

8,756 reviews

Delta

8.0

Very good

8,756 reviews

Reviews

1 / 10

Delta has consistently been the best U.S. airline for my travels and this flight was no exception

United Airlines

7.4

Good

9,171 reviews

Delta

8.0

Very good

8,756 reviews

Reviews

1 / 10

Delta has consistently been the best U.S. airline for my travels and this flight was no exception

American Airlines

7.2

Good

10,000 reviews

Delta

8.0

Very good

8,756 reviews

Reviews

1 / 10

Delta has consistently been the best U.S. airline for my travels and this flight was no exception

Avianca

7.0

Good

2,799 reviews

Delta

8.0

Very good

8,756 reviews

Reviews

1 / 10

Delta has consistently been the best U.S. airline for my travels and this flight was no exception

Related info for your journey

What are the cheapest airlines flying from Panama City to St. Louis round-trip?
Our cheapest airline available from Panama City to St. Louis is American Airlines. Our recent data shows that you can find tickets from as low as $495 on this airline. Additional options worth looking into are United Airlines and Avianca, starting at $514 and $2,140 round-trip. You may be able to fly from Panama City to St. Louis for 14% less than the average price by searching for these airlines.
Can I find deals for flights from Panama City to St. Louis that include hotel bookings?
Yes. In addition to deals on Panama City to St. Louis flights, Cheapflights offers vacation packages that include both flights and hotel.
How can I find direct flights from Panama City to St. Louis?
After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Panama City to St. Louis.
Can I find deals for business class flights from Panama City to St. Louis?
Yes. Cheapflights offers flight deals from Panama City to St. Louis by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.
What is the cheapest month to book a flight from Panama City to St. Louis?
Currently, September is the cheapest month in which you can book a flight from Panama City to St. Louis (average of $308). Flying from Panama City to St. Louis in March is currently the most expensive (average of $357). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Browse thousands of different options on Cheapflights for your next trip

Top 2 airlines flying from Panama City to St. Louis

Airline	Cheapest	Average	Flexibility	On-time
Delta	Cheapest$355	Average$599	FlexibilityNo cancel fee	On-timeN/A
United Airlines	Cheapest$386	Average$569	FlexibilityNo cancel fee	On-time69%

100% Free

Cheapflights is completely free to use, so you can start saving the moment you arrive.

Book with Flexibility

Our users can plan ahead with confidence and find flights with no change fees

Travel Smart

Millions of people come to us for their flight needs every year. We help make travel planning easy by providing useful insights and data-driven graphs that can inform your decisions.

View all available airlines

$295+ Cheap flights from Panama City (PTY) to St. Louis (STL)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 1/15. Fares are subject to change and may not be available on all flights or dates of travel.

Find cheap flights from Panama City to St. Louis with Cheapflights

1. Tell us where you want to go

2. Select your favorite providers

3. Compare prices and book

Cheap flight deals from Panama City to St. Louis

Most accurate provider

Most trusted provider

Popular in

Cheapest in

Round-trip from

One-way from

Find flight deals from Panama City to St. Louis

Best flights from Panama City to St. LouisDiscover carefully curated flight deals from Panama City to St. Louis that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated November 20, 2024.

Discover carefully curated flight deals from Panama City to St. Louis that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated November 20, 2024.

Find flights from Panama City to St. Louis within your budget

Compare providers for flights from Panama City to St. Louis

Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.

Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Panama City to St. Louis in November.

Best time to book a flight from Panama City to St. Louis

Have a flexible travel schedule? Discover the best time to fly to St. Louis from Panama City with our price prediction graph.

Travel insights for flights from Panama City to St. Louis

Get recent, data-driven insights about flights from Panama City to St. Louis including ideal travel times, pricing trends, and more.

What is the cheapest month to book a flight from Panama City to St. Louis?

What is the cheapest time of day to fly from PTY to STL?

Find hourly flight availability from Panama City to St. Louis. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated November 20, 2024.

Rainfall in St. Louis by month

Plan your trip to St. Louis by taking into account the average rainfall totals by month.

Temperature in St. Louis by month

Plan your trip to St. Louis by taking into account the average temperature totals by month.

Reviews of airlines servicing St. Louis

Related info for your journey

Find useful and relevant information for your journey from Panama City to St. Louis. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

What are the cheapest airlines flying from Panama City to St. Louis round-trip?

Can I find deals for flights from Panama City to St. Louis that include hotel bookings?

How can I find direct flights from Panama City to St. Louis?

Can I find deals for business class flights from Panama City to St. Louis?

What is the cheapest month to book a flight from Panama City to St. Louis?

Browse thousands of different options on Cheapflights for your next trip

Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.

Alternative routes for Panama City to St. Louis

See prices for flight routes from nearby airports that may be better suited for you.

Top 2 airlines flying from Panama City to St. Louis

100% Free

Book with Flexibility

Travel Smart

Best flights from Panama City to St. Louis
Discover carefully curated flight deals from Panama City to St. Louis that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated November 20, 2024.