What are the cheapest airlines to fly from Ohio to St. Louis one-way?

$58 is the cheapest one-way deal found within the past few days, from Spirit Airlines. You may also be able to find cheap deals on Frontier and American Airlines, with prices starting from $80 and $91, respectively.

What are the most popular routes from Ohio to St. Louis?

While some choose either Pittsburgh - Lambert-St Louis or Cleveland Hopkins Intl - Lambert-St Louis, Detroit Metropolitan Wayne County - Lambert-St Louis is the most popular route from Ohio to St. Louis.

What are the most popular airlines that fly from Ohio to St. Louis?

When booking a flight from Ohio to St. Louis, you may want to consider flying on American Airlines, Delta or United Airlines as they are the most popular for this route.

How far in advance should I book a flight from Ohio to St. Louis?

Travelers have found it’s best to book a flight 59 days in advance to save up to 144% compared to booking the same week of travel. As your travel date approaches, the cost of this flight route may potentially increase. While opting to book 59 days out may not be an option for all, there are still additional ways to secure a deal in the near future. You might find a flight from Ohio to St. Louis 1-2 weeks in advance for as low as $333, or $416 for flights within the next 24 hours.

What is the cheapest month to fly from Ohio to St. Louis?

June is one of the best times of the year to fly to St. Louis from Ohio. Prices for June average $316 per person but you can even find prices for as low as $142. The most expensive prices can be found in the month of January. Opting for a June flight can save you 53% on your journey compared to booking in January

What airport do you fly into for flights to St. Louis from Ohio?

Lambert-St Louis (STL), located 12.7 mi from the city center, is the airport you fly into when you book flights from Ohio to St. Louis.

Can I find deals for flights from Ohio to St. Louis that include hotel bookings?

Yes. In addition to deals on Ohio to St. Louis flights, Cheapflights offers vacation packages that include both flights and hotel.

How can I find direct flights from Ohio to St. Louis?

After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Ohio to St. Louis.

Can I find deals for business class flights from Ohio to St. Louis?

Yes. Cheapflights offers flight deals from Ohio to St. Louis by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

$58+ Flights from Ohio to St. Louis

Home Search by date Vacation packages Hotels Flight deals Car rental Travel tips & news

Find cheap flights from Ohio to St. Louis with Cheapflights

1. Tell us where you want to go

Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”

2. Select your favorite providers

We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.

3. Compare prices and book

Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.

Cheap flight deals from Ohio to St. Louis

Most accurate provider	FlightHub 3 stars
Most trusted provider	eDreams 3 stars
Round-trip from	$160 (Frontier)
One-way from	$58 (FlightHub)
Popular in	January
Cheapest in	June
Average price	$276
Good round-trip deal	$284 or less
Good one-way deal	$146 or less

Provider with most accurate pricing for Cleveland Hopkins Intl-Lambert-St Louis flight deals.

Search Deals

Provider most trusted by Cheapflights users for Cleveland Hopkins Intl-Lambert-St Louis flights.

Search Deals

From Ohio to Lambert-St Louis

Search Deals

One-way flight from Ohio to Lambert-St Louis

Search Deals

Highest demand for flights based on searches. 14% potential increase in price ($53 potential increase over avg. RT price).

Search Deals

Cheapest flight prices on average. 5% potential price decrease ($16 potential savings vs. average RT price).

Search Deals

Average for round-trip flights in April 2025

Search Deals

Price to beat on a round-trip flight from Ohio to Lambert-St Louis.

Search Deals

Price to beat on a one-way flight from Ohio to Lambert-St Louis.

Search Deals

Find flight deals from Ohio to St. Louis

Cheapest flights from Ohio to St. Louis
Explore the most affordable flight options available from Ohio to St. Louis. Find the lowest fares from popular airlines and budget airlines, with prices last updated on April 24, 2025.

Fri 5/167:29 pmCVG - STL

1 stop5h 45mFrontier

Mon 5/195:45 pmSTL - CVG

1 stop6h 14mFrontier

Deal found 4/22

$160

Wed 5/2111:28 amPIT - STL

1 stop8h 05mAmerican Airlines

Wed 5/286:00 amSTL - PIT

1 stop8h 45mAmerican Airlines

Deal found 4/23

$171

Wed 5/211:24 pmCMH - STL

1 stop9h 28mAmerican Airlines

Wed 5/286:00 amSTL - CMH

1 stop8h 56mAmerican Airlines

Deal found 4/22

$171

Mon 5/126:14 pmPIT - STL

1 stop6h 52mFrontier

Thu 5/155:45 pmSTL - PIT

1 stop22h 39mFrontier

Deal found 4/23

$180

Sat 5/243:10 pmCLE - STL

1 stop9h 34mFrontier

Tue 5/272:40 pmSTL - CLE

1 stop14h 20mFrontier

Deal found 4/24

$191

Sat 5/248:00 amCLE - STL

1 stop6h 07mAmerican Airlines

Mon 5/265:00 amSTL - CLE

1 stop8h 47mAmerican Airlines

Deal found 4/23

$196

Sun 4/275:50 pmCMH - STL

1 stop7h 14mFrontier

Wed 4/305:41 pmSTL - CMH

1 stop22h 28mFrontier

Deal found 4/23

$198

Sat 5/2412:35 pmCLE - STL

Nonstop1h 35mSouthwest

Mon 5/267:25 pmSTL - CLE

Nonstop1h 30mSouthwest

Deal found 4/23

$213

Sat 5/242:10 pmCLE - STL

1 stop3h 27mDelta

Wed 5/286:05 pmSTL - CLE

1 stop4h 52mDelta

Deal found 4/24

$216

Wed 5/214:10 pmDTW - STL

Nonstop1h 37mDelta

Wed 5/2810:45 amSTL - DTW

Nonstop1h 30mDelta

Deal found 4/23

$217

Mon 5/195:52 pmDTW - STL

1 stop6h 59mAmerican Airlines

Thu 5/225:12 amSTL - DTW

1 stop5h 05mAmerican Airlines

Deal found 4/22

$218

Wed 7/28:20 amCMH - STL

Nonstop1h 25mSouthwest

Sat 7/55:55 pmSTL - CMH

1 stop3h 40mSouthwest

Deal found 4/23

$221

Best flights from Ohio to St. Louis
Discover carefully curated flight deals from Ohio to St. Louis that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated April 24, 2025.

Fri 5/167:29 pmCVG - STL

1 stop5h 45mFrontier

Mon 5/195:45 pmSTL - CVG

1 stop6h 14mFrontier

Deal found 4/22

$160

Wed 5/2111:28 amPIT - STL

1 stop8h 05mAmerican Airlines

Wed 5/286:00 amSTL - PIT

1 stop8h 45mAmerican Airlines

Deal found 4/23

$171

Sat 5/2412:35 pmCLE - STL

Nonstop1h 35mSouthwest

Mon 5/267:25 pmSTL - CLE

Nonstop1h 30mSouthwest

Deal found 4/23

$213

Sat 5/242:10 pmCLE - STL

1 stop3h 27mDelta

Wed 5/286:05 pmSTL - CLE

1 stop4h 52mDelta

Deal found 4/24

$216

Mon 7/711:10 amDTW - STL

1 stop12h 35mUnited Airlines

Wed 7/95:00 amSTL - DTW

1 stop14h 45mUnited Airlines

Deal found 4/23

$263

Thu 6/121:10 pmDTW - STL

3 stops22h 23mSpirit Airlines

Sun 6/156:12 pmSTL - DTW

Nonstop1h 28mSpirit Airlines

Deal found 4/23

$265

Mon 5/1910:31 amDTW - STL

2 stops9h 10mMultiple Airlines

Thu 5/229:50 amSTL - DTW

2 stops22h 46mMultiple Airlines

Deal found 4/22

$284

Wed 5/211:24 pmCMH - STL

1 stop9h 28mAmerican Airlines

Wed 5/286:00 amSTL - CMH

1 stop8h 56mAmerican Airlines

Deal found 4/22

$171

Mon 5/126:14 pmPIT - STL

1 stop6h 52mFrontier

Thu 5/155:45 pmSTL - PIT

1 stop22h 39mFrontier

Deal found 4/23

$180

Sat 5/243:10 pmCLE - STL

1 stop9h 34mFrontier

Tue 5/272:40 pmSTL - CLE

1 stop14h 20mFrontier

Deal found 4/24

$191

Sat 5/248:00 amCLE - STL

1 stop6h 07mAmerican Airlines

Mon 5/265:00 amSTL - CLE

1 stop8h 47mAmerican Airlines

Deal found 4/23

$196

Wed 5/214:10 pmDTW - STL

Nonstop1h 37mDelta

Wed 5/2810:45 amSTL - DTW

Nonstop1h 30mDelta

Deal found 4/23

$217

Last-minute flights from Ohio to St. Louis
Discover last-minute flight deals from Ohio to St. Louis. Data last updated April 24, 2025 and is based on user searches.

Sun 4/275:50 pmCMH - STL

1 stop7h 14mFrontier

Wed 4/305:41 pmSTL - CMH

1 stop22h 28mFrontier

Deal found 4/23

$198

Wed 4/309:00 amPIT - STL

1 stop4h 20mUnited Airlines

Wed 5/79:40 amSTL - PIT

1 stop4h 44mUnited Airlines

Deal found 4/23

$478

Thu 5/17:28 pmCLE - STL

1 stop14h 41mFrontier

Fri 5/29:55 pmSTL - CLE

1 stop18h 30mFrontier

Deal found 4/23

$208

Thu 5/17:00 amCAK - STL

1 stop6h 20mUnited Airlines

Tue 5/69:40 amSTL - CAK

1 stop6h 41mUnited Airlines

Deal found 4/23

$329

Thu 5/16:40 amCAK - STL

2 stops9h 13mAmerican Airlines

Tue 5/65:12 amSTL - CAK

1 stop5h 17mAmerican Airlines

Deal found 4/23

$355

Thu 5/16:39 pmPIT - STL

2 stops25h 02mMultiple Airlines

Sun 5/46:10 pmSTL - PIT

1 stop13h 39mMultiple Airlines

Deal found 4/23

$423

Thu 5/111:45 amCLE - STL

1 stop5h 05mSouthwest

Fri 5/27:45 amSTL - CLE

2 stops6h 50mSouthwest

Deal found 4/23

$444

Thu 5/16:30 amCMH - STL

1 stop3h 58mDelta

Sun 5/45:32 pmSTL - CMH

1 stop5h 27mDelta

Deal found 4/23

$479

Fri 5/27:29 pmCVG - STL

1 stop5h 45mFrontier

Sun 5/45:45 pmSTL - CVG

1 stop6h 14mFrontier

Deal found 4/23

$210

Fri 5/22:33 pmDTW - STL

1 stop20h 26mFrontier

Sun 5/45:45 pmSTL - DTW

1 stop23h 15mFrontier

Deal found 4/23

$230

Fri 5/21:10 pmCVG - STL

2 stops8h 35mSouthwest

Sun 5/45:55 amSTL - CVG

1 stop5h 15mSouthwest

Deal found 4/23

$512

Sun 5/47:32 amDTW - STL

1 stop4h 31mUnited Airlines

Fri 5/95:29 pmSTL - DTW

1 stop5h 08mUnited Airlines

Deal found 4/23

$509

One-way flights from Ohio to St. Louis
Search for one-way flight options from Ohio to St. Louis. Find affordable one-way fares based on user searches. Data last updated April 24, 2025.

Thu 6/124:33 pmDTW - STL

Nonstop1h 31mSpirit Airlines

Deal found 4/23

$58

Fri 5/166:09 pmCLE - STL

1 stop7h 05mFrontier

Deal found 4/22

$80

Fri 5/167:29 pmCVG - STL

1 stop5h 45mFrontier

Deal found 4/23

$80

Sat 5/243:19 pmDTW - STL

1 stop9h 25mFrontier

Deal found 4/24

$89

Fri 5/96:14 pmPIT - STL

1 stop7h 00mFrontier

Deal found 4/23

$90

Tue 6/246:20 amCLE - STL

1 stop7h 31mAmerican Airlines

Deal found 4/23

$91

Tue 6/105:27 amDTW - STL

1 stop8h 24mAmerican Airlines

Deal found 4/23

$91

Tue 6/245:11 amPIT - STL

1 stop8h 40mAmerican Airlines

Deal found 4/23

$91

Tue 5/137:05 amCVG - STL

1 stop9h 16mAmerican Airlines

Deal found 4/22

$91

Mon 5/267:08 amCMH - STL

1 stop9h 13mAmerican Airlines

Deal found 4/23

$91

Sat 5/2412:51 pmCMH - STL

1 stop11h 53mFrontier

Deal found 4/23

$95

Sat 6/147:50 pmDTW - STL

Nonstop1h 40mDelta

Deal found 4/23

$100

Cheapflights Fare Finder

Use the filters below to find and compare flights from Ohio to St. Louis that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

CincinnatiSt. Louis

CVG - STL

CVGSTL

Cincinnati Cinci./N. Kentucky

Fri 5/16

7:29 pm-12:14 am

1 stop5h 45m

Lambert-St Louis

Mon 5/19

5:45 pm-12:59 am

1 stop6h 14m

$160

PittsburghSt. Louis

PIT - STL

PITSTL

Pittsburgh

Wed 5/21

11:28 am-6:33 pm

1 stop8h 05m

Lambert-St Louis

Wed 5/28

6:00 am-3:45 pm

1 stop8h 45m

$171

ColumbusSt. Louis

CMH - STL

CMHSTL

Columbus

Wed 5/21

1:24 pm-9:52 pm

1 stop9h 28m

Lambert-St Louis

Wed 5/28

6:00 am-3:56 pm

1 stop8h 56m

$171

PittsburghSt. Louis

PIT - STL

PITSTL

Pittsburgh

Mon 5/12

6:14 pm-12:06 am

1 stop6h 52m

Lambert-St Louis

Thu 5/15

5:45 pm-5:24 pm

1 stop22h 39m

$180

ClevelandSt. Louis

CLE - STL

CLESTL

Cleveland Hopkins Intl

Sat 5/24

3:10 pm-11:44 pm

1 stop9h 34m

Lambert-St Louis

Tue 5/27

2:40 pm-6:00 am

1 stop14h 20m

$191

ClevelandSt. Louis

CLE - STL

CLESTL

Cleveland Hopkins Intl

Sat 5/24

8:00 am-1:07 pm

1 stop6h 07m

Lambert-St Louis

Mon 5/26

5:00 am-2:47 pm

1 stop8h 47m

$196

ColumbusSt. Louis

CMH - STL

CMHSTL

Columbus

Sun 4/27

5:50 pm-12:04 am

1 stop7h 14m

Lambert-St Louis

Wed 4/30

5:41 pm-5:09 pm

1 stop22h 28m

$198

ClevelandSt. Louis

CLE - STL

CLESTL

Cleveland Hopkins Intl

Sat 5/24

12:35 pm-1:10 pm

Nonstop1h 35m

Lambert-St Louis

Mon 5/26

7:25 pm-9:55 pm

Nonstop1h 30m

$213

ClevelandSt. Louis

CLE - STL

CLESTL

Cleveland Hopkins Intl

Sat 5/24

2:10 pm-4:37 pm

1 stop3h 27m

Lambert-St Louis

Wed 5/28

6:05 pm-11:57 pm

1 stop4h 52m

$216

DetroitSt. Louis

DTW - STL

DTWSTL

Detroit Metropolitan Wayne County

Wed 5/21

4:10 pm-4:47 pm

Nonstop1h 37m

Lambert-St Louis

Wed 5/28

10:45 am-1:15 pm

Nonstop1h 30m

$217

Flights are sorted by cheapest round-trip flights first.

Deals found on 4/23

Showing 1-10 of 60 results

...

Best time to book a flight from Ohio to St. Louis

Have a flexible travel schedule? Discover the best time to fly to St. Louis from Ohio with our price prediction graph.

Estimated round-trip price

Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Ohio to St. Louis

What is the cheapest month to book a flight from Ohio to St. Louis?

Currently, August is the cheapest month in which you can book a flight from Ohio to St. Louis (average of $311). Flying from Ohio to St. Louis in March is currently the most expensive (average of $356). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from OH to STL?

When flying from Ohio to St. Louis, the time of day you decide to fly out makes little to no difference towards the overall price you’ll pay on tickets.

Rainfall in St. Louis by month

In terms of precipitation, rainfall in St. Louis ranges from 2.2 - 4.7 inches per month. May is typically the wettest month, when rainfall can reach 4.7 in. February is typically the driest time to visit St. Louis when rainfall is around 2.2 in.

Temperature in St. Louis by month

If weather is an important factor for your trip to St. Louis, use this chart to help with planning. For those seeking warmer temperatures, July is the ideal time of year to visit, when temperatures reach an average of 80.6 F. Travelers looking to avoid the cold should look outside of January, when temperatures are typically at their lowest (around 32.0 F).

Reviews of airlines servicing St. Louis

Read through reviews of airlines operating flights from Ohio to St. Louis, such as Alaska Airlines, Southwest and Delta. Users have also rated airlines in terms of entertainment options, comfort, food, crew/service, and boarding process.

Alaska Airlines

8.0

Very good

9,918 reviews

Reviews

1 / 20

4.0

Okay

Anonymous,Apr 2025

LAS - STS

flight was delayed both ways even tho the weather was clear >

Alaska Airlines

8.0

Very good

9,918 reviews

Alaska Airlines

8.0

Very good

9,918 reviews

Reviews

1 / 20

4.0

Okay

Anonymous,Apr 2025

LAS - STS

flight was delayed both ways even tho the weather was clear >

Southwest

8.0

Very good

4,286 reviews

Alaska Airlines

8.0

Very good

9,918 reviews

Reviews

1 / 20

4.0

Okay

Anonymous,Apr 2025

LAS - STS

flight was delayed both ways even tho the weather was clear >

Delta

8.0

Very good

7,920 reviews

Alaska Airlines

8.0

Very good

9,918 reviews

Reviews

1 / 20

4.0

Okay

Anonymous,Apr 2025

LAS - STS

flight was delayed both ways even tho the weather was clear >

United Airlines

7.4

Good

8,685 reviews

Alaska Airlines

8.0

Very good

9,918 reviews

Reviews

1 / 20

4.0

Okay

Anonymous,Apr 2025

LAS - STS

flight was delayed both ways even tho the weather was clear >

American Airlines

7.2

Good

10,000 reviews

Alaska Airlines

8.0

Very good

9,918 reviews

Reviews

1 / 20

4.0

Okay

Anonymous,Apr 2025

LAS - STS

flight was delayed both ways even tho the weather was clear >

Related info for your journey

What airport do you fly into for flights to St. Louis from Ohio?
Lambert-St Louis (STL), located 12.7 mi from the city center, is the airport you fly into when you book flights from Ohio to St. Louis.
What are the cheapest airlines to fly from Ohio to St. Louis one-way?
$58 is the cheapest one-way deal found within the past few days, from Spirit Airlines. You may also be able to find cheap deals on Frontier and American Airlines, with prices starting from $80 and $91, respectively.
What are the most popular routes from Ohio to St. Louis?
While some choose either Pittsburgh - Lambert-St Louis or Cleveland Hopkins Intl - Lambert-St Louis, Detroit Metropolitan Wayne County - Lambert-St Louis is the most popular route from Ohio to St. Louis.
Can I find deals for flights from Ohio to St. Louis that include hotel bookings?
Yes. In addition to deals on Ohio to St. Louis flights, Cheapflights offers vacation packages that include both flights and hotel.
How can I find direct flights from Ohio to St. Louis?
After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Ohio to St. Louis.
Can I find deals for business class flights from Ohio to St. Louis?
Yes. Cheapflights offers flight deals from Ohio to St. Louis by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.
What is the cheapest month to book a flight from Ohio to St. Louis?
Currently, August is the cheapest month in which you can book a flight from Ohio to St. Louis (average of $311). Flying from Ohio to St. Louis in March is currently the most expensive (average of $356). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Fenton

Maryland Heights

Fairview Heights

Collinsville

Wentzville

Eureka

St. Peters

Festus

Glencoe

Alton

Farmington

Browse thousands of different options on Cheapflights for your next trip

Top 5 airlines flying from Ohio to St. Louis

Airline	Cheapest	Average	Flexibility	On-time
Frontier	Cheapest$116	Average$188	FlexibilityNo cancel fee	On-time62%
Delta	Cheapest$162	Average$334	FlexibilityNo cancel fee	On-timeN/A
American Airlines	Cheapest$191	Average$338	FlexibilityNo cancel fee	On-time71%
United Airlines	Cheapest$193	Average$364	FlexibilityNo cancel fee	On-time69%
Southwest	Cheapest$229	Average$337	FlexibilityNo cancel fee	On-time63%

100% Free

Cheapflights is completely free to use, so you can start saving the moment you arrive.

Book with Flexibility

Our users can plan ahead with confidence and find flights with no change fees

Travel Smart

Millions of people come to us for their flight needs every year. We help make travel planning easy by providing useful insights and data-driven graphs that can inform your decisions.

$58+ Cheap flights from Ohio to St. Louis (STL)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 6/12. Fares are subject to change and may not be available on all flights or dates of travel.

Find cheap flights from Ohio to St. Louis with Cheapflights

1. Tell us where you want to go

2. Select your favorite providers

3. Compare prices and book

Cheap flight deals from Ohio to St. Louis

Keep the following information in mind while searching for Ohio to St. Louis flight deals. Data was last updated April 24, 2025.

Most accurate provider

Most trusted provider

Round-trip from

One-way from

Popular in

Cheapest in

Average price

Good round-trip deal

Good one-way deal

Find flight deals from Ohio to St. Louis

Cheapest flights from Ohio to St. LouisExplore the most affordable flight options available from Ohio to St. Louis. Find the lowest fares from popular airlines and budget airlines, with prices last updated on April 24, 2025.

Explore the most affordable flight options available from Ohio to St. Louis. Find the lowest fares from popular airlines and budget airlines, with prices last updated on April 24, 2025.

Cheapflights Fare Finder

Use the filters below to find and compare flights from Ohio to St. Louis that are best for you.

Best time to book a flight from Ohio to St. Louis

Have a flexible travel schedule? Discover the best time to fly to St. Louis from Ohio with our price prediction graph.

Cheapflights Insights

Everything you need to know about your flight from Ohio to St. Louis

What is the cheapest month to book a flight from Ohio to St. Louis?

What is the cheapest time of day to fly from OH to STL?

Find hourly flight availability from Ohio to St. Louis. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated April 24, 2025.

Rainfall in St. Louis by month

Plan your trip to St. Louis by taking into account the average rainfall totals by month.

Temperature in St. Louis by month

Plan your trip to St. Louis by taking into account the average temperature totals by month.

Reviews of airlines servicing St. Louis

Read through reviews of airlines operating flights from Ohio to St. Louis, such as Alaska Airlines, Southwest and Delta. Users have also rated airlines in terms of entertainment options, comfort, food, crew/service, and boarding process.

Related info for your journey

Find useful and relevant information for your journey from Ohio to St. Louis. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

What airport do you fly into for flights to St. Louis from Ohio?

What are the cheapest airlines to fly from Ohio to St. Louis one-way?

What are the most popular routes from Ohio to St. Louis?

Can I find deals for flights from Ohio to St. Louis that include hotel bookings?

How can I find direct flights from Ohio to St. Louis?

Can I find deals for business class flights from Ohio to St. Louis?

What is the cheapest month to book a flight from Ohio to St. Louis?

Traveling to a place near Ohio?

Browse thousands of different options on Cheapflights for your next trip

Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.

Alternative routes for Ohio to St. Louis

See prices for flight routes from nearby airports that may be better suited for you.

Top 5 airlines flying from Ohio to St. Louis

100% Free

Book with Flexibility

Travel Smart

Cheapest flights from Ohio to St. Louis
Explore the most affordable flight options available from Ohio to St. Louis. Find the lowest fares from popular airlines and budget airlines, with prices last updated on April 24, 2025.