What are the cheapest airlines to fly from Mississippi to St. Louis one-way?

For one-way options, check prices for Frontier. According to our data, you can fly for as low as $86. Users have also found prices from $141 and $160 on Southwest and American Airlines, respectively.

What are the most popular routes from Mississippi to St. Louis?

Most travelers choose Baton Rouge Ryan - Lambert-St Louis, Memphis - Lambert-St Louis or Jackson-Evers Intl - Lambert-St Louis when deciding on the best route from Mississippi to St. Louis.

What is the cheapest month to fly from Mississippi to St. Louis?

Due to multiple factors, expect to potentially pay more when booking in June. For low rates, November can be a great choice for travel to St. Louis. Flights to St. Louis from Mississippi in November are about $347 on average during November, but can be found for as low as $226.

What airport do you fly into for flights to St. Louis from Mississippi?

For a flight from Mississippi to St. Louis, you will be flying into Lambert-St Louis. Lambert-St Louis (STL) is just 12.7 mi from the center of the city.

Can I find deals for flights from Mississippi to St. Louis that include hotel bookings?

Yes. In addition to deals on Mississippi to St. Louis flights, Cheapflights offers vacation packages that include both flights and hotel.

How can I find direct flights from Mississippi to St. Louis?

After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Mississippi to St. Louis.

Can I find deals for business class flights from Mississippi to St. Louis?

Yes. Cheapflights offers flight deals from Mississippi to St. Louis by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

$86+ Flights from Mississippi to St. Louis

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Cheap flight deals from Mississippi to St. Louis

Most accurate provider	FlightHub 3 stars
Most trusted provider	FlightHub 3 stars
Round-trip from	$161 (CheapOair)
One-way from	$86 (CheapOair)
Popular in	June
Cheapest in	November

Provider with most accurate pricing for Jackson-Evers Intl-Lambert-St Louis flight deals.

Search Deals

Provider most trusted by Cheapflights users for Jackson-Evers Intl-Lambert-St Louis flights.

Search Deals

From Mississippi to Lambert-St Louis

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One-way flight from Mississippi to Lambert-St Louis

Search Deals

Highest demand for flights based on searches. 20% potential increase in price ($88 potential increase over avg. RT price).

Search Deals

Cheapest flight prices on average. 7% potential price decrease ($24 potential savings vs. average RT price).

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Find flight deals from Mississippi to St. Louis

Cheapest flights from Mississippi to St. Louis
Explore the most affordable flight options available from Mississippi to St. Louis. Find the lowest fares from popular airlines and budget airlines, with prices last updated on March 31, 2025.

Tue 4/157:53 pmMEM - STL

1 stop13h 13mFrontier

Sun 4/2012:41 pmSTL - MEM

1 stop5h 58mFrontier

Deal found 3/30

$161

Sat 4/265:40 pmJAN - STL

1 stop5h 56mDelta

Sat 5/37:10 amSTL - JAN

1 stop6h 53mDelta

Deal found 3/30

$237

Sat 4/267:05 amJAN - STL

2 stops9h 06mAmerican Airlines

Sat 5/35:00 amSTL - JAN

1 stop5h 34mAmerican Airlines

Deal found 3/30

$242

Sat 4/264:23 pmBTR - STL

1 stop6h 05mAmerican Airlines

Sat 5/33:44 pmSTL - BTR

1 stop7h 01mAmerican Airlines

Deal found 3/30

$249

Wed 4/235:45 pmBTR - STL

1 stop5h 51mDelta

Mon 5/57:10 amSTL - BTR

1 stop6h 13mDelta

Deal found 3/30

$269

Thu 4/1012:46 pmMOB - STL

1 stop6h 37mAmerican Airlines

Sun 4/137:04 amSTL - MOB

1 stop4h 54mAmerican Airlines

Deal found 3/30

$279

Thu 4/248:47 amMEM - STL

1 stop8h 28mMultiple Airlines

Sun 4/276:10 pmSTL - MEM

2 stops24h 32mMultiple Airlines

Deal found 3/29

$283

Thu 5/295:10 amBTR - STL

1 stop5h 29mUnited Airlines

Sun 6/15:55 pmSTL - BTR

1 stop5h 04mUnited Airlines

Deal found 3/31

$294

Fri 8/295:40 amJAN - STL

2 stops7h 55mSouthwest

Sun 8/317:45 amSTL - JAN

1 stop5h 35mSouthwest

Deal found 3/30

$317

Tue 9/26:00 pmGPT - STL

1 stop5h 39mDelta

Fri 9/511:51 amSTL - GPT

1 stop5h 25mDelta

Deal found 3/30

$329

Tue 9/212:43 pmGPT - STL

2 stops7h 04mAmerican Airlines

Fri 9/55:35 amSTL - GPT

1 stop4h 47mAmerican Airlines

Deal found 3/29

$352

Fri 4/2510:55 amMEM - STL

1 stop6h 28mUnited Airlines

Wed 4/303:40 pmSTL - MEM

1 stop6h 34mUnited Airlines

Deal found 3/30

$357

Best flights from Mississippi to St. Louis
Discover carefully curated flight deals from Mississippi to St. Louis that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated March 31, 2025.

Tue 4/157:53 pmMEM - STL

1 stop13h 13mFrontier

Sun 4/2012:41 pmSTL - MEM

1 stop5h 58mFrontier

Deal found 3/30

$161

Sat 4/265:40 pmJAN - STL

1 stop5h 56mDelta

Sat 5/37:10 amSTL - JAN

1 stop6h 53mDelta

Deal found 3/30

$237

Sat 4/267:05 amJAN - STL

2 stops9h 06mAmerican Airlines

Sat 5/35:00 amSTL - JAN

1 stop5h 34mAmerican Airlines

Deal found 3/30

$242

Thu 4/248:47 amMEM - STL

1 stop8h 28mMultiple Airlines

Sun 4/276:10 pmSTL - MEM

2 stops24h 32mMultiple Airlines

Deal found 3/29

$283

Thu 5/295:10 amBTR - STL

1 stop5h 29mUnited Airlines

Sun 6/15:55 pmSTL - BTR

1 stop5h 04mUnited Airlines

Deal found 3/31

$294

Fri 8/295:40 amJAN - STL

2 stops7h 55mSouthwest

Sun 8/317:45 amSTL - JAN

1 stop5h 35mSouthwest

Deal found 3/30

$317

Sat 4/264:23 pmBTR - STL

1 stop6h 05mAmerican Airlines

Sat 5/33:44 pmSTL - BTR

1 stop7h 01mAmerican Airlines

Deal found 3/30

$249

Wed 4/235:45 pmBTR - STL

1 stop5h 51mDelta

Mon 5/57:10 amSTL - BTR

1 stop6h 13mDelta

Deal found 3/30

$269

Thu 4/1012:46 pmMOB - STL

1 stop6h 37mAmerican Airlines

Sun 4/137:04 amSTL - MOB

1 stop4h 54mAmerican Airlines

Deal found 3/30

$279

Fri 4/255:05 amMEM - STL

1 stop4h 10mSouthwest

Wed 4/305:00 pmSTL - MEM

1 stop5h 40mSouthwest

Deal found 3/30

$357

Tue 9/26:00 pmGPT - STL

1 stop5h 39mDelta

Fri 9/511:51 amSTL - GPT

1 stop5h 25mDelta

Deal found 3/30

$329

Fri 4/255:20 pmMOB - STL

1 stop4h 49mUnited Airlines

Sun 4/276:15 amSTL - MOB

1 stop7h 18mUnited Airlines

Deal found 3/29

$425

Last-minute flights from Mississippi to St. Louis
Discover last-minute flight deals from Mississippi to St. Louis. Data last updated March 31, 2025 and is based on user searches.

Tue 4/88:00 amMEM - STL

1 stop6h 42mUnited Airlines

Tue 4/155:35 pmSTL - MEM

1 stop4h 39mUnited Airlines

Deal found 3/29

$479

Wed 4/97:39 pmMEM - STL

3 stops37h 11mMultiple Airlines

Fri 4/1112:15 pmSTL - MEM

3 stops31h 37mMultiple Airlines

Deal found 3/30

$705

Thu 4/107:44 pmMEM - STL

1 stop13h 22mFrontier

Sun 4/1312:22 pmSTL - MEM

1 stop6h 17mFrontier

Deal found 3/29

$248

Thu 4/1012:46 pmMOB - STL

1 stop6h 37mAmerican Airlines

Sun 4/137:04 amSTL - MOB

1 stop4h 54mAmerican Airlines

Deal found 3/30

$279

Thu 4/106:25 pmMEM - STL

1 stop4h 25mSouthwest

Sun 4/136:10 amSTL - MEM

2 stops5h 50mSouthwest

Deal found 3/29

$538

Tue 4/157:53 pmMEM - STL

1 stop13h 13mFrontier

Sun 4/2012:41 pmSTL - MEM

1 stop5h 58mFrontier

Deal found 3/30

$161

Fri 4/185:00 amMEM - STL

1 stop5h 33mAmerican Airlines

Sun 4/206:00 amSTL - MEM

1 stop5h 52mAmerican Airlines

Deal found 3/30

$429

Wed 4/235:45 pmBTR - STL

1 stop5h 51mDelta

Mon 5/57:10 amSTL - BTR

1 stop6h 13mDelta

Deal found 3/30

$269

Thu 4/248:47 amMEM - STL

1 stop8h 28mMultiple Airlines

Sun 4/276:10 pmSTL - MEM

2 stops24h 32mMultiple Airlines

Deal found 3/29

$283

Fri 4/256:50 pmJAN - STL

1 stop4h 00mSouthwest

Sun 4/276:10 amSTL - JAN

2 stops5h 50mSouthwest

Deal found 3/29

$349

Fri 4/255:05 amMEM - STL

1 stop4h 10mSouthwest

Wed 4/305:00 pmSTL - MEM

1 stop5h 40mSouthwest

Deal found 3/30

$357

Fri 4/255:20 pmMOB - STL

1 stop4h 49mUnited Airlines

Sun 4/276:15 amSTL - MOB

1 stop7h 18mUnited Airlines

Deal found 3/29

$425

One-way flights from Mississippi to St. Louis
Search for one-way flight options from Mississippi to St. Louis. Find affordable one-way fares based on user searches. Data last updated March 31, 2025.

Thu 4/243:54 pmMEM - STL

1 stop18h 07mFrontier

Deal found 3/30

$86

Fri 5/25:35 amJAN - STL

1 stop4h 25mSouthwest

Deal found 3/30

$141

Thu 5/15:20 amBTR - STL

1 stop5h 13mAmerican Airlines

Deal found 3/31

$160

Tue 5/277:00 amMEM - STL

1 stop6h 07mAmerican Airlines

Deal found 3/30

$171

Thu 5/15:05 amBTR - STL

2 stops9h 42mUnited Airlines

Deal found 3/31

$181

Fri 4/253:10 pmMEM - STL

1 stop9h 25mSouthwest

Deal found 3/30

$188

Thu 4/248:47 amMEM - STL

3 stops33h 54mMultiple Airlines

Deal found 3/30

$198

Tue 5/277:30 amMEM - STL

2 stops26h 26mUnited Airlines

Deal found 3/31

$314

Mon 4/75:48 pmBTR - STL

1 stop5h 41mDelta

Deal found 3/30

$336

Sat 4/128:55 pmMEM - STL

3 stops20h 20mSpirit Airlines

Deal found 3/31

$368

Cheapflights Fare Finder

Use the filters below to find and compare flights from Mississippi to St. Louis that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

MemphisSt. Louis

MEM - STL

MEMSTL

Memphis

Tue 4/15

7:53 pm-9:06 am

1 stop13h 13m

Lambert-St Louis

Sun 4/20

12:41 pm-6:39 pm

1 stop5h 58m

$161

JacksonSt. Louis

JAN - STL

JANSTL

Jackson-Evers Intl

Sat 4/26

5:40 pm-11:36 pm

1 stop5h 56m

Lambert-St Louis

Sat 5/3

7:10 am-2:03 pm

1 stop6h 53m

$237

JacksonSt. Louis

JAN - STL

JANSTL

Jackson-Evers Intl

Sat 4/26

7:05 am-4:11 pm

2 stops9h 06m

Lambert-St Louis

Sat 5/3

5:00 am-10:34 am

1 stop5h 34m

$242

Baton RougeSt. Louis

BTR - STL

BTRSTL

Baton Rouge Ryan

Sat 4/26

4:23 pm-10:28 pm

1 stop6h 05m

Lambert-St Louis

Sat 5/3

3:44 pm-10:45 pm

1 stop7h 01m

$249

Baton RougeSt. Louis

BTR - STL

BTRSTL

Baton Rouge Ryan

Wed 4/23

5:45 pm-11:36 pm

1 stop5h 51m

Lambert-St Louis

Mon 5/5

7:10 am-1:23 pm

1 stop6h 13m

$269

MobileSt. Louis

MOB - STL

MOBSTL

Mobile

Thu 4/10

12:46 pm-7:23 pm

1 stop6h 37m

Lambert-St Louis

Sun 4/13

7:04 am-11:58 am

1 stop4h 54m

$279

MemphisSt. Louis

MEM - STL

MEMSTL

Memphis

Thu 4/24

8:47 am-5:15 pm

1 stop8h 28m

Lambert-St Louis

Sun 4/27

6:10 pm-6:42 pm

2 stops24h 32m

$283

Baton RougeSt. Louis

BTR - STL

BTRSTL

Baton Rouge Ryan

Thu 5/29

5:10 am-10:39 am

1 stop5h 29m

Lambert-St Louis

Sun 6/1

5:55 pm-10:59 pm

1 stop5h 04m

$294

JacksonSt. Louis

JAN - STL

JANSTL

Jackson-Evers Intl

Fri 8/29

5:40 am-1:35 pm

2 stops7h 55m

Lambert-St Louis

Sun 8/31

7:45 am-1:20 pm

1 stop5h 35m

$317

GulfportSt. Louis

GPT - STL

GPTSTL

Gulfport Biloxi Regional

Tue 9/2

6:00 pm-11:39 pm

1 stop5h 39m

Lambert-St Louis

Fri 9/5

11:51 am-5:16 pm

1 stop5h 25m

$329

Flights are sorted by cheapest round-trip flights first.

Deals found on 3/30

Showing 1-10 of 29 results

Best time to book a flight from Mississippi to St. Louis

Have a flexible travel schedule? Discover the best time to fly to St. Louis from Mississippi with our price prediction graph.

Estimated round-trip price

Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Mississippi to St. Louis

What is the cheapest month to book a flight from Mississippi to St. Louis?

Currently, August is the cheapest month in which you can book a flight from Mississippi to St. Louis (average of $311). Flying from Mississippi to St. Louis in March is currently the most expensive (average of $356). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from MS to STL?

Regardless of the time of day you decide to fly, the ticket price will remain around the same. Book flights from Mississippi to St. Louis as you normally would.

Rainfall in St. Louis by month

In terms of precipitation, rainfall in St. Louis ranges from 2.2 - 4.7 inches per month. May is typically the wettest month, when rainfall can reach 4.7 in. February is typically the driest time to visit St. Louis when rainfall is around 2.2 in.

Temperature in St. Louis by month

If weather is an important factor for your trip to St. Louis, use this chart to help with planning. For those seeking warmer temperatures, July is the ideal time of year to visit, when temperatures reach an average of 80.6 F. Travelers looking to avoid the cold should look outside of January, when temperatures are typically at their lowest (around 32.0 F).

Reviews of airlines servicing St. Louis

To help decide which airline to fly from Mississippi to St. Louis, see what other customers have to say about Southwest, Delta and United Airlines. Users have also rated airlines in terms of entertainment options, comfort, food, crew/service, and boarding process.

Southwest

8.0

Very good

4,275 reviews

Reviews

1 / 20

8.0

Excellent

Ila,Mar 2025

HOU - DAL

Our original flight was delayed. We were able to change our flight and got home at close to the same time. Looking forward to when you have assigned seating.

Southwest

8.0

Very good

4,275 reviews

Southwest

8.0

Very good

4,275 reviews

Reviews

1 / 20

8.0

Excellent

Ila,Mar 2025

HOU - DAL

Our original flight was delayed. We were able to change our flight and got home at close to the same time. Looking forward to when you have assigned seating.

Delta

8.0

Very good

7,899 reviews

Southwest

8.0

Very good

4,275 reviews

Reviews

1 / 20

8.0

Excellent

Ila,Mar 2025

HOU - DAL

Our original flight was delayed. We were able to change our flight and got home at close to the same time. Looking forward to when you have assigned seating.

United Airlines

7.4

Good

8,614 reviews

Southwest

8.0

Very good

4,275 reviews

Reviews

1 / 20

8.0

Excellent

Ila,Mar 2025

HOU - DAL

Our original flight was delayed. We were able to change our flight and got home at close to the same time. Looking forward to when you have assigned seating.

American Airlines

7.2

Good

10,000 reviews

Southwest

8.0

Very good

4,275 reviews

Reviews

1 / 20

8.0

Excellent

Ila,Mar 2025

HOU - DAL

Our original flight was delayed. We were able to change our flight and got home at close to the same time. Looking forward to when you have assigned seating.

Spirit Airlines

6.3

Okay

7,883 reviews

Southwest

8.0

Very good

4,275 reviews

Reviews

1 / 20

8.0

Excellent

Ila,Mar 2025

HOU - DAL

Our original flight was delayed. We were able to change our flight and got home at close to the same time. Looking forward to when you have assigned seating.

Related info for your journey

What airport do you fly into for flights to St. Louis from Mississippi?
For a flight from Mississippi to St. Louis, you will be flying into Lambert-St Louis. Lambert-St Louis (STL) is just 12.7 mi from the center of the city.
What are the cheapest airlines to fly from Mississippi to St. Louis one-way?
For one-way options, check prices for Frontier. According to our data, you can fly for as low as $86. Users have also found prices from $141 and $160 on Southwest and American Airlines, respectively.
What are the most popular routes from Mississippi to St. Louis?
Most travelers choose Baton Rouge Ryan - Lambert-St Louis, Memphis - Lambert-St Louis or Jackson-Evers Intl - Lambert-St Louis when deciding on the best route from Mississippi to St. Louis.
Can I find deals for flights from Mississippi to St. Louis that include hotel bookings?
Yes. In addition to deals on Mississippi to St. Louis flights, Cheapflights offers vacation packages that include both flights and hotel.
How can I find direct flights from Mississippi to St. Louis?
After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Mississippi to St. Louis.
Can I find deals for business class flights from Mississippi to St. Louis?
Yes. Cheapflights offers flight deals from Mississippi to St. Louis by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.
What is the cheapest month to book a flight from Mississippi to St. Louis?
Currently, August is the cheapest month in which you can book a flight from Mississippi to St. Louis (average of $311). Flying from Mississippi to St. Louis in March is currently the most expensive (average of $356). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Fenton

Maryland Heights

Fairview Heights

Collinsville

Wentzville

Eureka

St. Peters

Festus

Glencoe

Alton

Farmington

Chesterfield

Browse thousands of different options on Cheapflights for your next trip

Top 2 airlines flying from Mississippi to St. Louis

Airline	Cheapest	Average	Flexibility	On-time
Delta	Cheapest$224	Average$347	FlexibilityNo cancel fee	On-timeN/A
American Airlines	Cheapest$226	Average$303	FlexibilityNo cancel fee	On-time71%

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$86+ Cheap flights from Mississippi to St. Louis (STL)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 4/24. Fares are subject to change and may not be available on all flights or dates of travel.

Find cheap flights from Mississippi to St. Louis with Cheapflights

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Cheap flight deals from Mississippi to St. Louis

Keep the following information in mind while searching for Mississippi to St. Louis flight deals. Data was last updated March 31, 2025.

Most accurate provider

Most trusted provider

Round-trip from

One-way from

Popular in

Cheapest in

Find flight deals from Mississippi to St. Louis

Cheapest flights from Mississippi to St. LouisExplore the most affordable flight options available from Mississippi to St. Louis. Find the lowest fares from popular airlines and budget airlines, with prices last updated on March 31, 2025.

Explore the most affordable flight options available from Mississippi to St. Louis. Find the lowest fares from popular airlines and budget airlines, with prices last updated on March 31, 2025.

Cheapflights Fare Finder

Use the filters below to find and compare flights from Mississippi to St. Louis that are best for you.

Best time to book a flight from Mississippi to St. Louis

Have a flexible travel schedule? Discover the best time to fly to St. Louis from Mississippi with our price prediction graph.

Cheapflights Insights

Everything you need to know about your flight from Mississippi to St. Louis

What is the cheapest month to book a flight from Mississippi to St. Louis?

What is the cheapest time of day to fly from MS to STL?

Find hourly flight availability from Mississippi to St. Louis. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated March 31, 2025.

Rainfall in St. Louis by month

Plan your trip to St. Louis by taking into account the average rainfall totals by month.

Temperature in St. Louis by month

Plan your trip to St. Louis by taking into account the average temperature totals by month.

Reviews of airlines servicing St. Louis

To help decide which airline to fly from Mississippi to St. Louis, see what other customers have to say about Southwest, Delta and United Airlines. Users have also rated airlines in terms of entertainment options, comfort, food, crew/service, and boarding process.

Related info for your journey

Find useful and relevant information for your journey from Mississippi to St. Louis. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

What airport do you fly into for flights to St. Louis from Mississippi?

What are the cheapest airlines to fly from Mississippi to St. Louis one-way?

What are the most popular routes from Mississippi to St. Louis?

Can I find deals for flights from Mississippi to St. Louis that include hotel bookings?

How can I find direct flights from Mississippi to St. Louis?

Can I find deals for business class flights from Mississippi to St. Louis?

What is the cheapest month to book a flight from Mississippi to St. Louis?

Traveling to a place near Mississippi?

Browse thousands of different options on Cheapflights for your next trip

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Alternative routes for Mississippi to St. Louis

See prices for flight routes from nearby airports that may be better suited for you.

Top 2 airlines flying from Mississippi to St. Louis

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Cheapest flights from Mississippi to St. Louis
Explore the most affordable flight options available from Mississippi to St. Louis. Find the lowest fares from popular airlines and budget airlines, with prices last updated on March 31, 2025.