HomeSearch by dateVacation packagesHotelsFlight dealsCar rentalTravel tips & news
St. Louis

$109+ Cheap flights from Mississippi to St. Louis (STL)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 2/26. Fares are subject to change and may not be available on all flights or dates of travel.
JAN — STL
feb. 4 — feb. 111
mar. 2/4
mar. 2/11
1 adult, Economy
We work with more than 300 partners to bring you better travel deals

Find cheap flights from Mississippi to St. Louis with Cheapflights

1. Tell us where you want to go
Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”
2. Select your favorite providers
We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.
3. Compare prices and book
Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.

Cheap flight deals from Mississippi to St. Louis

Discover tips and strategies to find the most affordable flight options for your journey from Mississippi (USMS) to St. Louis (STL). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated enero 30, 2025.

Most accurate provider

FlightHub
3 stars

Most trusted provider

FlightHub
3 stars

Round-trip from

$140
(CheapOair)

One-way from

$109
(United Airlines)

Popular in

June

Cheapest in

November

Average price

$313
Provider with most accurate pricing for Jackson-Evers Intl-Lambert-St Louis flight deals.
Search Deals
Provider most trusted by Cheapflights users for Jackson-Evers Intl-Lambert-St Louis flights.
Search Deals
From Mississippi to Lambert-St Louis
Search Deals
One-way flight from Mississippi to Lambert-St Louis
Search Deals
Highest demand for flights based on searches. 18% potential increase in price ($81 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 6% potential price decrease ($23 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in January 2025
Search Deals

Find flight deals from Mississippi to St. Louis

Cheapest flights from Mississippi to St. Louis
Explore the most affordable flight options available from Mississippi to St. Louis. Find the lowest fares from popular airlines and budget airlines, with prices last updated on enero 30, 2025.

This CheapOair deal was found by Cheapflights users on 1/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
jue. 2/208:15 pmMEM - STL
1 stop13h 01mFrontier
sáb. 2/227:04 pmSTL - MEM
1 stop24h 21mFrontier
Deal found 1/30$140
This American Airlines deal was found by Cheapflights users on 1/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
sáb. 2/155:17 amMOB - STL
1 stop4h 42mAmerican Airlines
sáb. 2/226:00 amSTL - MOB
2 stops12h 02mAmerican Airlines
Deal found 1/30$205
This Southwest deal was found by Cheapflights users on 1/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
lun. 3/106:45 pmMEM - STL
1 stop6h 10mSouthwest
mié. 3/126:00 amSTL - MEM
1 stop8h 00mSouthwest
Deal found 1/30$217
This American Airlines deal was found by Cheapflights users on 1/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
sáb. 2/224:34 pmBTR - STL
1 stop7h 22mAmerican Airlines
mar. 2/259:15 amSTL - BTR
1 stop7h 09mAmerican Airlines
Deal found 1/30$224
This Delta deal was found by Cheapflights users on 1/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
sáb. 2/156:00 amMOB - STL
1 stop5h 46mDelta
sáb. 2/2212:52 pmSTL - MOB
1 stop4h 22mDelta
Deal found 1/30$232
This Delta deal was found by Cheapflights users on 1/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
dom. 5/257:30 amBTR - STL
1 stop7h 05mDelta
dom. 6/15:40 pmSTL - BTR
1 stop4h 21mDelta
Deal found 1/29$249
This Delta deal was found by Cheapflights users on 1/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
sáb. 4/265:35 pmJAN - STL
1 stop6h 03mDelta
sáb. 5/36:00 amSTL - JAN
1 stop5h 21mDelta
Deal found 1/30$277
This American Airlines deal was found by Cheapflights users on 1/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mar. 3/47:10 amMEM - STL
1 stop14h 52mAmerican Airlines
jue. 3/610:12 amSTL - MEM
1 stop10h 48mAmerican Airlines
Deal found 1/30$303
This United Airlines deal was found by Cheapflights users on 1/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
sáb. 5/3112:06 pmBTR - STL
2 stops10h 39mUnited Airlines
mar. 6/38:25 amSTL - BTR
1 stop5h 02mUnited Airlines
Deal found 1/29$324
This American Airlines deal was found by Cheapflights users on 1/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
sáb. 3/17:05 amJAN - STL
1 stop4h 54mAmerican Airlines
vie. 3/75:06 amSTL - JAN
1 stop5h 21mAmerican Airlines
Deal found 1/30$352
This United Airlines deal was found by Cheapflights users on 1/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
lun. 3/245:11 pmJAN - STL
1 stop4h 56mUnited Airlines
mar. 3/256:15 amSTL - JAN
1 stop5h 05mUnited Airlines
Deal found 1/30$356
This United Airlines deal was found by Cheapflights users on 1/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
vie. 2/148:00 amMOB - STL
1 stop26h 05mUnited Airlines
mar. 2/184:30 pmSTL - MOB
1 stop5h 30mUnited Airlines
Deal found 1/30$399

Find flights from Mississippi to St. Louis within your budget

Customize your flight search to find flights from Mississippi to St. Louis that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated enero 30, 2025.

Fly from

Any airport

Fly to

Any airport

Route

Depart

Return

Price

MemphisSt. Louis

MEM - STL

MEMSTL

Memphis

jue. 2/20

8:15 pm-9:16 am

1 stop13h 01m

Lambert-St Louis

sáb. 2/22

7:04 pm-7:25 pm

1 stop24h 21m

$140

MobileSt. Louis

MOB - STL

MOBSTL

Mobile

sáb. 2/15

5:17 am-9:59 am

1 stop4h 42m

Lambert-St Louis

sáb. 2/22

6:00 am-6:02 pm

2 stops12h 02m

$205

MemphisSt. Louis

MEM - STL

MEMSTL

Memphis

lun. 3/10

6:45 pm-12:55 am

1 stop6h 10m

Lambert-St Louis

mié. 3/12

6:00 am-2:00 pm

1 stop8h 00m

$217

Baton RougeSt. Louis

BTR - STL

BTRSTL

Baton Rouge Ryan

sáb. 2/22

4:34 pm-11:56 pm

1 stop7h 22m

Lambert-St Louis

mar. 2/25

9:15 am-4:24 pm

1 stop7h 09m

$224

MobileSt. Louis

MOB - STL

MOBSTL

Mobile

sáb. 2/15

6:00 am-11:46 am

1 stop5h 46m

Lambert-St Louis

sáb. 2/22

12:52 pm-5:14 pm

1 stop4h 22m

$232

JacksonSt. Louis

JAN - STL

JANSTL

Jackson-Evers Intl

mié. 4/23

6:59 pm-11:38 pm

1 stop4h 39m

Lambert-St Louis

mar. 5/6

5:40 pm-11:20 pm

1 stop5h 40m

$247

Baton RougeSt. Louis

BTR - STL

BTRSTL

Baton Rouge Ryan

dom. 5/25

7:30 am-2:35 pm

1 stop7h 05m

Lambert-St Louis

dom. 6/1

5:40 pm-10:01 pm

1 stop4h 21m

$249

JacksonSt. Louis

JAN - STL

JANSTL

Jackson-Evers Intl

vie. 5/2

6:50 pm-10:50 pm

1 stop4h 00m

Lambert-St Louis

sáb. 5/3

8:35 am-5:45 pm

2 stops9h 10m

$282

MemphisSt. Louis

MEM - STL

MEMSTL

Memphis

mar. 3/4

7:10 am-10:02 pm

1 stop14h 52m

Lambert-St Louis

jue. 3/6

10:12 am-9:00 pm

1 stop10h 48m

$303

Baton RougeSt. Louis

BTR - STL

BTRSTL

Baton Rouge Ryan

sáb. 5/31

12:06 pm-10:45 pm

2 stops10h 39m

Lambert-St Louis

mar. 6/3

8:25 am-1:27 pm

1 stop5h 02m

$324

Flights are sorted by cheapest round-trip flights first.

Deals found on 1/30

Showing 1-10 of 29 results
1
2
3

Best time to book a flight from Mississippi to St. Louis

Have a flexible travel schedule? Discover the best time to fly to St. Louis from Mississippi with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Travel insights for flights from Mississippi to St. Louis

Get recent, data-driven insights about flights from Mississippi to St. Louis including ideal travel times, pricing trends, and more.

What is the cheapest month to book a flight from Mississippi to St. Louis?

Currently, August is the cheapest month in which you can book a flight from Mississippi to St. Louis (average of $311). Flying from Mississippi to St. Louis in March is currently the most expensive (average of $356). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from MS to STL?

Find hourly flight availability from Mississippi to St. Louis. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated enero 30, 2025.

Regardless of the time of day you decide to fly, the ticket price will remain around the same. Book flights from Mississippi to St. Louis as you normally would.

Rainfall in St. Louis by month

Plan your trip to St. Louis by taking into account the average rainfall totals by month.

In terms of precipitation, rainfall in St. Louis ranges from 2.2 - 4.7 inches per month. May is typically the wettest month, when rainfall can reach 4.7 in. February is typically the driest time to visit St. Louis when rainfall is around 2.2 in.

Temperature in St. Louis by month

Plan your trip to St. Louis by taking into account the average temperature totals by month.

If weather is an important factor for your trip to St. Louis, use this chart to help with planning. For those seeking warmer temperatures, July is the ideal time of year to visit, when temperatures reach an average of 80.6 F. Travelers looking to avoid the cold should look outside of January, when temperatures are typically at their lowest (around 32.0 F).

Reviews of airlines servicing St. Louis

Get insights into the airlines that provide service to St. Louis. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to St. Louis. Reviews last updated enero 30, 2025.
To help decide which airline to fly from Mississippi to St. Louis, see what other customers have to say about Southwest, Delta and United Airlines. Users have also rated airlines in terms of entertainment options, comfort, food, crew/service, and boarding process.
Southwest
8.1
Very good
4,585 reviews

Food

7.1

Overall

8.1

Crew

8.7

Entertainment

7.7

Boarding

8.2

Comfort

8.1

Reviews

1 / 20

6.0
Good

Lauren,Dec 2024

MCI - DCA

We BARELY made the connection and when we got onboard we were treated like disobedient children who should have arrived earlier because we had to ask other passengers to move so we could sit with our kids. The flight attendants on the first flight were nice but the second one, they were snippy and fairly rude.

Southwest
8.1
Very good
4,585 reviews
Southwest
8.1
Very good
4,585 reviews

Food

7.1

Overall

8.1

Crew

8.7

Entertainment

7.7

Boarding

8.2

Comfort

8.1

Reviews

1 / 20

6.0
Good

Lauren,Dec 2024

MCI - DCA

We BARELY made the connection and when we got onboard we were treated like disobedient children who should have arrived earlier because we had to ask other passengers to move so we could sit with our kids. The flight attendants on the first flight were nice but the second one, they were snippy and fairly rude.

Delta
8.0
Very good
8,450 reviews
Southwest
8.1
Very good
4,585 reviews

Food

7.1

Overall

8.1

Crew

8.7

Entertainment

7.7

Boarding

8.2

Comfort

8.1

Reviews

1 / 20

6.0
Good

Lauren,Dec 2024

MCI - DCA

We BARELY made the connection and when we got onboard we were treated like disobedient children who should have arrived earlier because we had to ask other passengers to move so we could sit with our kids. The flight attendants on the first flight were nice but the second one, they were snippy and fairly rude.

United Airlines
7.4
Good
8,906 reviews
Southwest
8.1
Very good
4,585 reviews

Food

7.1

Overall

8.1

Crew

8.7

Entertainment

7.7

Boarding

8.2

Comfort

8.1

Reviews

1 / 20

6.0
Good

Lauren,Dec 2024

MCI - DCA

We BARELY made the connection and when we got onboard we were treated like disobedient children who should have arrived earlier because we had to ask other passengers to move so we could sit with our kids. The flight attendants on the first flight were nice but the second one, they were snippy and fairly rude.

American Airlines
7.2
Good
10,000 reviews
Southwest
8.1
Very good
4,585 reviews

Food

7.1

Overall

8.1

Crew

8.7

Entertainment

7.7

Boarding

8.2

Comfort

8.1

Reviews

1 / 20

6.0
Good

Lauren,Dec 2024

MCI - DCA

We BARELY made the connection and when we got onboard we were treated like disobedient children who should have arrived earlier because we had to ask other passengers to move so we could sit with our kids. The flight attendants on the first flight were nice but the second one, they were snippy and fairly rude.

Spirit Airlines
6.3
Okay
8,083 reviews
Southwest
8.1
Very good
4,585 reviews

Food

7.1

Overall

8.1

Crew

8.7

Entertainment

7.7

Boarding

8.2

Comfort

8.1

Reviews

1 / 20

6.0
Good

Lauren,Dec 2024

MCI - DCA

We BARELY made the connection and when we got onboard we were treated like disobedient children who should have arrived earlier because we had to ask other passengers to move so we could sit with our kids. The flight attendants on the first flight were nice but the second one, they were snippy and fairly rude.

Related info for your journey

Find useful and relevant information for your journey from Mississippi to St. Louis. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly into for flights to St. Louis from Mississippi?

    For a flight from Mississippi to St. Louis, you will be flying into Lambert-St Louis. Lambert-St Louis (STL) is just 12.7 mi from the center of the city.

  • What are the cheapest airlines to fly from Mississippi to St. Louis one-way?

    For one-way options, check prices for United Airlines. According to our data, you can fly for as low as $109. Users have also found prices from $114 and $142 on Southwest and Frontier, respectively.

  • What are the most popular routes from Mississippi to St. Louis?

    Most travelers choose Gulfport Biloxi Regional - Lambert-St Louis, Baton Rouge Ryan - Lambert-St Louis or Mobile - Lambert-St Louis when deciding on the best route from Mississippi to St. Louis.

  • Can I find deals for flights from Mississippi to St. Louis that include hotel bookings?

    Yes. In addition to deals on Mississippi to St. Louis flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Mississippi to St. Louis?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Mississippi to St. Louis.

  • Can I find deals for business class flights from Mississippi to St. Louis?

    Yes. Cheapflights offers flight deals from Mississippi to St. Louis by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Mississippi to St. Louis?

    Currently, August is the cheapest month in which you can book a flight from Mississippi to St. Louis (average of $311). Flying from Mississippi to St. Louis in March is currently the most expensive (average of $356). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Traveling to a place near Mississippi?

Book flights to Mississippi if you plan to visit one of these locations
Fenton
Fairview Heights
Maryland Heights
Collinsville
Wentzville
Eureka
St. Peters
Festus
Alton
Farmington
Chesterfield

Browse thousands of different options on Cheapflights for your next trip

Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.

Alternative routes for Mississippi to St. Louis

See prices for flight routes from nearby airports that may be better suited for you.
Newark to St. Louis flights
LaGuardia to St. Louis flights
O'Hare Intl to Kansas City flights
LaGuardia to Kansas City flights
Denver to Kansas City flights
Dulles Intl to St. Louis flights
Los Angeles to Kansas City flights
Newark to Kansas City flights
John F Kennedy Intl to St. Louis flights
John F Kennedy Intl to Kansas City flights
Dallas/Fort Worth to St. Louis flights
Dallas/Fort Worth to Kansas City flights
Boston to St. Louis flights
Los Angeles to St. Louis flights
Seattle to Kansas City flights
Dulles Intl to Kansas City flights
Atlanta to Kansas City flights
Denver to St. Louis flights
Atlanta to St. Louis flights
Boston to Kansas City flights
Minneapolis to St. Louis flights
Seattle to St. Louis flights
San Francisco to St. Louis flights
Sky Harbor Intl to Kansas City flights
Reagan-National to Kansas City flights
Reagan-National to St. Louis flights
Philadelphia to St. Louis flights
Baltimore to St. Louis flights
O'Hare Intl to St. Louis flights
San Francisco to Kansas City flights
Orlando to St. Louis flights
Ontario to Kansas City flights
Philadelphia to Kansas City flights
Detroit to Kansas City flights
Baltimore to Kansas City flights
Charlotte to St. Louis flights
Hobby to Kansas City flights
Sky Harbor Intl to St. Louis flights
Detroit to St. Louis flights
Hobby to St. Louis flights
Salt Lake City to Kansas City flights
George Bush Intcntl to St. Louis flights
George Bush Intcntl to Kansas City flights
Tampa to Kansas City flights
Orlando to Kansas City flights
Raleigh to St. Louis flights
Ontario to St. Louis flights
Midway to Kansas City flights
Minneapolis to Kansas City flights
Midway to St. Louis flights

Top 2 airlines flying from Mississippi to St. Louis

Discover the top 2 airlines that operate flights from Mississippi to St. Louis. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated enero 30, 2025.
AirlineCheapestAverageFlexibilityOn-time
DeltaCheapest$224Average$348FlexibilityNo cancel feeOn-timeN/A
American AirlinesCheapest$226Average$316FlexibilityNo cancel feeOn-time71%
100% Free
Cheapflights is completely free to use, so you can start saving the moment you arrive.
Book with Flexibility
Our users can plan ahead with confidence and find flights with no change fees
Travel Smart
Millions of people come to us for their flight needs every year. We help make travel planning easy by providing useful insights and data-driven graphs that can inform your decisions.