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$38+ Cheap flights from Mesa, AZ to St. Louis (STL)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 3/25. Fares are subject to change and may not be available on all flights or dates of travel.
PHX — STL
feb. 25 — mar. 41
mar. 2/25
mar. 3/4
1 adult, Economy
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The best prices from Mesa to Lambert-St Louis are usually found in June or July, booked 89 days in advance, depart on a Wednesday or Friday and return on a Wednesday

Cheap flight deals from Mesa to St. Louis

Keep the following information in mind while searching for Mesa to St. Louis flight deals. Data was last updated febrero 20, 2025.

Round-trip from

$159
(Mytrip)

One-way from

$38
(Trip.com)

Popular in

January

Cheapest in

June

Average price

$387
From Mesa to Lambert-St Louis
Search Deals
One-way flight from Mesa to Lambert-St Louis
Search Deals
Highest demand for flights based on searches. 24% potential increase in price ($102 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 3% potential price decrease ($12 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in February 2025
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Find flight deals from Mesa to St. Louis

Cheapest flights from Mesa to St. Louis
Explore the most affordable flight options available from Mesa to St. Louis. Find the lowest fares from popular airlines and budget airlines, with prices last updated on febrero 20, 2025.

This Mytrip deal was found by Cheapflights users on 2/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
sáb. 3/1510:51 pmPHX - STL
1 stop22h 58mFrontier
lun. 3/176:55 pmSTL - PHX
1 stop28h 33mFrontier
Deal found 2/18$159
This Expedia deal was found by Cheapflights users on 2/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mar. 3/189:15 pmPHX - STL
1 stop10h 01mMultiple Airlines
mar. 4/13:11 pmSTL - PHX
1 stop11h 01mMultiple Airlines
Deal found 2/20$227
This Mytrip deal was found by Cheapflights users on 2/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
lun. 4/75:15 amPHX - STL
3 stops34h 37mSpirit Airlines
jue. 4/106:11 pmSTL - PHX
2 stops21h 21mSpirit Airlines
Deal found 2/18$313
This Delta deal was found by Cheapflights users on 2/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mié. 5/1411:25 amPHX - STL
1 stop8h 08mDelta
mar. 5/202:15 pmSTL - PHX
1 stop6h 13mDelta
Deal found 2/19$323
This United Airlines deal was found by Cheapflights users on 2/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
sáb. 5/38:30 amPHX - STL
1 stop5h 19mUnited Airlines
dom. 5/46:15 amSTL - PHX
1 stop7h 03mUnited Airlines
Deal found 2/19$329
This American Airlines deal was found by Cheapflights users on 2/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
lun. 4/712:25 pmPHX - STL
Nonstop2h 58mAmerican Airlines
mié. 4/92:24 pmSTL - PHX
Nonstop3h 31mAmerican Airlines
Deal found 2/20$365
This Southwest deal was found by Cheapflights users on 2/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
lun. 3/177:50 pmPHX - STL
Nonstop2h 50mSouthwest
lun. 3/317:20 pmSTL - PHX
1 stop6h 00mSouthwest
Deal found 2/20$371
This Alaska Airlines deal was found by Cheapflights users on 2/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Alaska Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mar. 3/188:06 pmPHX - STL
1 stop25h 53mAlaska Airlines
mar. 4/16:44 amSTL - PHX
2 stops14h 07mAlaska Airlines
Deal found 2/20$403

Find flights from Mesa to St. Louis within your budget

Customize your flight search to find flights from Mesa to St. Louis that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated febrero 20, 2025.

Fly from

Mesa

Fly to

St. Louis

Route

Depart

Return

Price

PhoenixSt. Louis

PHX - STL

PHXSTL

Phoenix Sky Harbor Intl

sáb. 3/15

10:51 pm-11:49 pm

1 stop22h 58m

Lambert-St Louis

lun. 3/17

6:55 pm-9:28 pm

1 stop28h 33m

$159

PhoenixSt. Louis

PHX - STL

PHXSTL

Phoenix Sky Harbor Intl

mar. 3/18

9:15 pm-9:16 am

1 stop10h 01m

Lambert-St Louis

mar. 4/1

3:11 pm-12:12 am

1 stop11h 01m

$227

PhoenixSt. Louis

PHX - STL

PHXSTL

Phoenix Sky Harbor Intl

lun. 4/7

5:15 am-5:52 pm

3 stops34h 37m

Lambert-St Louis

jue. 4/10

6:11 pm-1:32 pm

2 stops21h 21m

$313

PhoenixSt. Louis

PHX - STL

PHXSTL

Phoenix Sky Harbor Intl

mié. 5/14

11:25 am-9:33 pm

1 stop8h 08m

Lambert-St Louis

mar. 5/20

2:15 pm-6:28 pm

1 stop6h 13m

$323

PhoenixSt. Louis

PHX - STL

PHXSTL

Phoenix Sky Harbor Intl

sáb. 5/3

8:30 am-3:49 pm

1 stop5h 19m

Lambert-St Louis

dom. 5/4

6:15 am-11:18 am

1 stop7h 03m

$329

PhoenixSt. Louis

PHX - STL

PHXSTL

Phoenix Sky Harbor Intl

lun. 4/7

12:25 pm-5:23 pm

Nonstop2h 58m

Lambert-St Louis

mié. 4/9

2:24 pm-3:55 pm

Nonstop3h 31m

$365

PhoenixSt. Louis

PHX - STL

PHXSTL

Phoenix Sky Harbor Intl

lun. 3/17

7:50 pm-12:40 am

Nonstop2h 50m

Lambert-St Louis

lun. 3/31

7:20 pm-11:20 pm

1 stop6h 00m

$371

PhoenixSt. Louis

PHX - STL

PHXSTL

Phoenix Sky Harbor Intl

mar. 3/18

8:06 pm-11:59 pm

1 stop25h 53m

Lambert-St Louis

mar. 4/1

6:44 am-6:51 pm

2 stops14h 07m

$403

PhoenixSt. Louis

PHX - STL

PHXSTL

Phoenix Sky Harbor Intl

mar. 3/25

9:15 pm-9:16 am

1 stop10h 01m

$38

PhoenixSt. Louis

PHX - STL

PHXSTL

Phoenix Sky Harbor Intl

mié. 4/2

5:15 am-5:52 pm

3 stops34h 37m

$118

Flights are sorted by cheapest round-trip flights first.

Deals found on 2/19

Showing 1-10 of 16 results
1
2

Best time to book a flight from Mesa to St. Louis

Have a flexible travel schedule? Discover the best time to fly to St. Louis from Mesa with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Travel insights for flights from Mesa to St. Louis

Get recent, data-driven insights about flights from Mesa to St. Louis including ideal travel times, pricing trends, and more.

How far ahead should I book a flight from Mesa to St. Louis?

Use this chart to determine the optimal time to book a round-trip flight from Mesa to St. Louis. Price data was last updated on February 14, 2025.

Booking 89 days in advance of your planned departure date is, on average, the best time to get cheap flights from Mesa to St. Louis. The general trend is that the closer you book to the departure date, the more expensive your flight will be.

What is the cheapest month to book a flight from Mesa to St. Louis?

Currently, August is the cheapest month in which you can book a flight from Mesa to St. Louis (average of $311). Flying from Mesa to St. Louis in March is currently the most expensive (average of $356). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from MS9 to STL?

Find hourly flight availability from Mesa to St. Louis. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated febrero 20, 2025.

When flying from Mesa to St. Louis, the time of day you decide to fly out makes little to no difference towards the overall price you’ll pay on tickets.

What is the cheapest day to fly from Mesa to St. Louis?

Use this chart to determine the cheapest time to fly round-trip from Mesa to St. Louis. Price data was last updated on December 16, 2024.

Travelers seeking maximum savings on their Mesa to St. Louis flight should consider departing on Wednesday afternoons when fares are most often at their lowest. Monday at noon flights should be avoided if possible as fares are typically the most expensive at this time.

Weekly flight availability from Mesa to St. Louis

Explore weekly flight availability from Mesa to St. Louis. Discover flights operating on different days of the week, giving you the flexibility to choose a travel day that best fits your plans. Compare info to find the most convenient option for your journey. Data last updated febrero 20, 2025.

The most flights from MS9 to STL are scheduled on a Monday (10 on average). You will have fewer flight options on Saturday, which is when the least amount of flights are scheduled (2 on average).

Rainfall in St. Louis by month

Plan your trip to St. Louis by taking into account the average rainfall totals by month.

In terms of precipitation, rainfall in St. Louis ranges from 2.2 - 4.7 inches per month. May is typically the wettest month, when rainfall can reach 4.7 in. February is typically the driest time to visit St. Louis when rainfall is around 2.2 in.

Temperature in St. Louis by month

Plan your trip to St. Louis by taking into account the average temperature totals by month.

If weather is an important factor for your trip to St. Louis, use this chart to help with planning. For those seeking warmer temperatures, July is the ideal time of year to visit, when temperatures reach an average of 80.6 F. Travelers looking to avoid the cold should look outside of January, when temperatures are typically at their lowest (around 32.0 F).

Reviews of airlines servicing St. Louis

Get insights into the airlines that provide service to St. Louis. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to St. Louis. Reviews last updated febrero 20, 2025.
To help decide which airline to fly from Mesa to St. Louis, see what other customers have to say about Southwest, Alaska Airlines and Delta. Reviews also offer insight into each airline's entertainment options, comfort, food, crew/service, and boarding process.
Southwest
8.1
Very good
4,411 reviews

Crew

8.7

Overall

8.1

Boarding

8.2

Entertainment

7.6

Food

7.1

Comfort

8.1

Reviews

1 / 20

2.0
Mediocre

Anonymous,Feb 2025

MCO - STL

Cancelled at last minute, SWA unable to assist in formulating alternate plans. Wound up renting a car and driving 13 hours to beat bad weather forecast at home. Not SWA’s fault that there was significant bad weather across the country.

Southwest
8.1
Very good
4,411 reviews
Southwest
8.1
Very good
4,411 reviews

Crew

8.7

Overall

8.1

Boarding

8.2

Entertainment

7.6

Food

7.1

Comfort

8.1

Reviews

1 / 20

2.0
Mediocre

Anonymous,Feb 2025

MCO - STL

Cancelled at last minute, SWA unable to assist in formulating alternate plans. Wound up renting a car and driving 13 hours to beat bad weather forecast at home. Not SWA’s fault that there was significant bad weather across the country.

Alaska Airlines
8.0
Very good
9,697 reviews
Southwest
8.1
Very good
4,411 reviews

Crew

8.7

Overall

8.1

Boarding

8.2

Entertainment

7.6

Food

7.1

Comfort

8.1

Reviews

1 / 20

2.0
Mediocre

Anonymous,Feb 2025

MCO - STL

Cancelled at last minute, SWA unable to assist in formulating alternate plans. Wound up renting a car and driving 13 hours to beat bad weather forecast at home. Not SWA’s fault that there was significant bad weather across the country.

Delta
8.0
Very good
8,219 reviews
Southwest
8.1
Very good
4,411 reviews

Crew

8.7

Overall

8.1

Boarding

8.2

Entertainment

7.6

Food

7.1

Comfort

8.1

Reviews

1 / 20

2.0
Mediocre

Anonymous,Feb 2025

MCO - STL

Cancelled at last minute, SWA unable to assist in formulating alternate plans. Wound up renting a car and driving 13 hours to beat bad weather forecast at home. Not SWA’s fault that there was significant bad weather across the country.

United Airlines
7.4
Good
8,765 reviews
Southwest
8.1
Very good
4,411 reviews

Crew

8.7

Overall

8.1

Boarding

8.2

Entertainment

7.6

Food

7.1

Comfort

8.1

Reviews

1 / 20

2.0
Mediocre

Anonymous,Feb 2025

MCO - STL

Cancelled at last minute, SWA unable to assist in formulating alternate plans. Wound up renting a car and driving 13 hours to beat bad weather forecast at home. Not SWA’s fault that there was significant bad weather across the country.

American Airlines
7.2
Good
10,000 reviews
Southwest
8.1
Very good
4,411 reviews

Crew

8.7

Overall

8.1

Boarding

8.2

Entertainment

7.6

Food

7.1

Comfort

8.1

Reviews

1 / 20

2.0
Mediocre

Anonymous,Feb 2025

MCO - STL

Cancelled at last minute, SWA unable to assist in formulating alternate plans. Wound up renting a car and driving 13 hours to beat bad weather forecast at home. Not SWA’s fault that there was significant bad weather across the country.

Related info for your journey

Find useful and relevant information for your journey from Mesa to St. Louis. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly into for flights to St. Louis from Mesa?

    For a flight from Mesa to St. Louis, you will be flying into Lambert-St Louis. Lambert-St Louis (STL) is just 12.7 mi from the center of the city. Lambert-St Louis is the only St. Louis airport and it handles 6 inbound flights from Mesa per day. 5 airlines have flights to Lambert-St Louis from Mesa on a regular basis.

  • What are the cheapest airlines to fly from Mesa to St. Louis one-way?

    For one-way options, check prices for Frontier. According to our data, you can fly for as low as $38. Users have also found prices from $118 and $162 on Spirit Airlines and Delta, respectively.

  • What are the most reliable airlines from Mesa to St. Louis?

    No one likes to see their flight delayed. When booking a flight from Mesa to St. Louis consider choosing SkyWest Airlines (100%), Alaska Airlines (93%) or American Airlines (91%) as they are the most reliable in getting you off to your destination on time.

  • What are the cheapest flights from Mesa to St. Louis?

    On average you can expect to pay $359 for a flight from Mesa to St. Louis. The cheapest flight overall is $158 while the most popular route, (Phoenix Sky Harbor Intl - Lambert-St Louis) is currently priced at $177.

  • Can I find deals for flights from Mesa to St. Louis that include hotel bookings?

    Yes. In addition to deals on Mesa to St. Louis flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Mesa to St. Louis?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Mesa to St. Louis.

  • Can I find deals for business class flights from Mesa to St. Louis?

    Yes. Cheapflights offers flight deals from Mesa to St. Louis by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Mesa to St. Louis?

    Currently, August is the cheapest month in which you can book a flight from Mesa to St. Louis (average of $311). Flying from Mesa to St. Louis in March is currently the most expensive (average of $356). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Traveling to a place near Mesa?

Book flights to Mesa if you plan to visit one of these locations
Fenton
Fairview Heights
Maryland Heights
Collinsville
Wentzville
Eureka
St. Peters
Festus
Alton
Farmington
Chesterfield

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Top 5 airlines flying from Mesa to St. Louis

Discover the top 5 airlines that operate flights from Mesa to St. Louis. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated febrero 20, 2025.
AirlineCheapestAverageFlexibilityOn-time
FrontierCheapest$78Average$148FlexibilityNo cancel feeOn-time62%
American AirlinesCheapest$131Average$327FlexibilityNo cancel feeOn-time71%
DeltaCheapest$216Average$296FlexibilityNo cancel feeOn-timeN/A
United AirlinesCheapest$273Average$386FlexibilityNo cancel feeOn-time69%
SouthwestCheapest$297Average$438FlexibilityNo cancel feeOn-time63%
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