What are the cheapest airlines to fly from Maine to St. Louis one-way?

One-way options have recently been found by users for as low as $114 on Frontier. Other airlines that offer cheap prices include United Airlines from $147 and Southwest from $152 one-way.

What are the most popular routes from Maine to St. Louis?

Most travelers choose Boston Logan Intl - Lambert-St Louis, Portland - Lambert-St Louis or Bangor - Lambert-St Louis when deciding on the best route from Maine to St. Louis.

What are the most popular airlines that fly from Maine to St. Louis?

Consider American Airlines, Delta or United Airlines when booking your flight. These represent the most popular airlines when flying from Maine to St. Louis.

How far in advance should I book a flight from Maine to St. Louis?

Travelers have found it’s best to book a flight 11 days in advance to save up to 145% compared to booking the same week of travel. As your travel date approaches, the cost of this flight route may potentially increase. While opting to book 11 days out may not be an option for all, there are still additional ways to secure a deal in the near future. You might find a flight from Maine to St. Louis 1-2 weeks in advance for as low as $228, or $639 for flights within the next 24 hours.

What is the cheapest month to fly from Maine to St. Louis?

Our data shows that February tends to be the cheapest month to fly to St. Louis from Maine. Users have commonly found prices around $434 for the month, but tickets can be as low as $213. Due to multiple factors, prepare for potentially higher prices in December.

What airport do you fly into for flights to St. Louis from Maine?

If you book a flight to St. Louis from Maine, you will be flying to Lambert-St Louis, which is the city’s only airport. Lambert-St Louis (STL) is located 12.7 mi from the center of St. Louis.

Can I find deals for flights from Maine to St. Louis that include hotel bookings?

Yes. In addition to deals on Maine to St. Louis flights, Cheapflights offers vacation packages that include both flights and hotel.

How can I find direct flights from Maine to St. Louis?

After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Maine to St. Louis.

Can I find deals for business class flights from Maine to St. Louis?

Yes. Cheapflights offers flight deals from Maine to St. Louis by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

$114+ Flights from Maine to St. Louis

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Cheap flight deals from Maine to St. Louis

Most accurate provider	FlightHub 3 stars
Most trusted provider	FlightHub 3 stars
Round-trip from	$208 (Booking.com)
One-way from	$114 (Expedia)
Popular in	December
Cheapest in	February
Average price	$499

Provider with most accurate pricing for Portland-Lambert-St Louis flight deals.

Search Deals

Provider most trusted by Cheapflights users for Portland-Lambert-St Louis flights.

Search Deals

From Maine to Lambert-St Louis

Search Deals

One-way flight from Maine to Lambert-St Louis

Search Deals

Highest demand for flights based on searches. 2% potential increase in price ($10 potential increase over avg. RT price).

Search Deals

Cheapest flight prices on average. 2% potential price decrease ($10 potential savings vs. average RT price).

Search Deals

Average for round-trip flights in April 2025

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Find flight deals from Maine to St. Louis

Cheapest flights from Maine to St. Louis
Explore the most affordable flight options available from Maine to St. Louis. Find the lowest fares from popular airlines and budget airlines, with prices last updated on April 1, 2025.

Mon 5/129:30 pmPWM - STL

1 stop27h 36mFrontier

Thu 5/155:45 pmSTL - PWM

1 stop25h 55mFrontier

Deal found 3/31

$208

Wed 10/154:59 pmBGR - STL

1 stop7h 30mAmerican Airlines

Sat 10/189:36 amSTL - BGR

1 stop4h 47mAmerican Airlines

Deal found 3/31

$259

Wed 5/214:01 pmPWM - STL

1 stop5h 57mAmerican Airlines

Wed 5/284:01 pmSTL - PWM

1 stop6h 54mAmerican Airlines

Deal found 3/31

$285

Wed 5/216:05 amPWM - STL

2 stops9h 30mDelta

Wed 5/286:00 amSTL - PWM

1 stop5h 57mDelta

Deal found 3/31

$290

Wed 4/99:55 amBOS - STL

3 stops33h 46mMultiple Airlines

Mon 4/149:50 amSTL - BOS

3 stops25h 46mMultiple Airlines

Deal found 3/30

$319

Tue 5/207:05 amBOS - STL

Nonstop2h 55mSouthwest

Sat 5/246:45 pmSTL - BOS

Nonstop2h 30mSouthwest

Deal found 3/31

$327

Wed 6/119:40 amBOS - STL

1 stop15h 09mFrontier

Sun 6/158:44 pmSTL - BOS

1 stop13h 17mFrontier

Deal found 3/31

$331

Sat 4/196:50 pmBOS - STL

1 stop5h 46mDelta

Tue 4/226:08 amSTL - BOS

1 stop5h 10mDelta

Deal found 3/31

$332

Tue 5/206:30 amBOS - STL

Nonstop3h 10mAmerican Airlines

Sat 5/246:20 amSTL - BOS

1 stop6h 36mAmerican Airlines

Deal found 3/31

$337

Mon 5/55:30 amBOS - STL

2 stops10h 17mUnited Airlines

Tue 5/66:30 amSTL - BOS

1 stop5h 18mUnited Airlines

Deal found 4/1

$363

Thu 7/245:40 pmPWM - STL

1 stop6h 40mSouthwest

Mon 7/285:25 amSTL - PWM

1 stop6h 10mSouthwest

Deal found 3/31

$387

Tue 4/811:14 amBOS - STL

1 stop7h 38mSpirit Airlines

Thu 4/246:10 pmSTL - BOS

1 stop15h 17mSpirit Airlines

Deal found 3/31

$493

Best flights from Maine to St. Louis
Discover carefully curated flight deals from Maine to St. Louis that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated April 1, 2025.

Mon 5/129:30 pmPWM - STL

1 stop27h 36mFrontier

Thu 5/155:45 pmSTL - PWM

1 stop25h 55mFrontier

Deal found 3/31

$208

Wed 5/214:01 pmPWM - STL

1 stop5h 57mAmerican Airlines

Wed 5/284:01 pmSTL - PWM

1 stop6h 54mAmerican Airlines

Deal found 3/31

$285

Wed 5/216:05 amPWM - STL

2 stops9h 30mDelta

Wed 5/286:00 amSTL - PWM

1 stop5h 57mDelta

Deal found 3/31

$290

Thu 5/85:42 pmBOS - STL

3 stops27h 28mMultiple Airlines

Sun 5/1110:10 amSTL - BOS

3 stops35h 41mMultiple Airlines

Deal found 3/31

$323

Tue 5/207:05 amBOS - STL

Nonstop2h 55mSouthwest

Sat 5/246:45 pmSTL - BOS

Nonstop2h 30mSouthwest

Deal found 3/31

$327

Fri 6/65:42 pmBOS - STL

2 stops16h 33mSpirit Airlines

Sun 6/810:10 amSTL - BOS

1 stop12h 19mSpirit Airlines

Deal found 4/1

$355

Mon 5/510:45 amBOS - STL

1 stop5h 02mUnited Airlines

Wed 5/76:30 amSTL - BOS

2 stops6h 49mUnited Airlines

Deal found 4/1

$363

Thu 5/111:39 amBOS - STL

1 stop24h 52mSun Country Air

Sun 5/48:00 amSTL - BOS

1 stop14h 04mSun Country Air

Deal found 3/30

$370

Thu 5/15:20 pmBOS - STL

1 stop31h 39mAlaska Airlines

Tue 5/66:30 amSTL - BOS

1 stop16h 29mAlaska Airlines

Deal found 3/31

$503

Wed 6/119:40 amBOS - STL

1 stop15h 09mFrontier

Sun 6/158:44 pmSTL - BOS

1 stop13h 17mFrontier

Deal found 3/31

$331

Sat 4/196:50 pmBOS - STL

1 stop5h 46mDelta

Tue 4/226:08 amSTL - BOS

1 stop5h 10mDelta

Deal found 3/31

$332

Tue 5/206:30 amBOS - STL

Nonstop3h 10mAmerican Airlines

Sat 5/246:20 amSTL - BOS

1 stop6h 36mAmerican Airlines

Deal found 3/31

$337

Last-minute flights from Maine to St. Louis
Discover last-minute flight deals from Maine to St. Louis. Data last updated April 1, 2025 and is based on user searches.

Wed 4/26:00 amBOS - STL

1 stop18h 46mFrontier

Sun 4/64:57 pmSTL - BOS

1 stop6h 50mFrontier

Deal found 4/1

$338

Tue 4/811:14 amBOS - STL

1 stop7h 38mSpirit Airlines

Thu 4/246:10 pmSTL - BOS

1 stop15h 17mSpirit Airlines

Deal found 3/31

$493

Tue 4/85:55 pmBOS - STL

Nonstop3h 05mSouthwest

Thu 4/242:20 pmSTL - BOS

Nonstop2h 35mSouthwest

Deal found 3/31

$592

Wed 4/99:55 amBOS - STL

3 stops33h 46mMultiple Airlines

Mon 4/149:50 amSTL - BOS

3 stops25h 46mMultiple Airlines

Deal found 3/30

$319

Wed 4/912:39 pmBGR - STL

1 stop5h 42mAmerican Airlines

Sun 4/136:13 amSTL - BGR

1 stop4h 53mAmerican Airlines

Deal found 4/1

$369

Wed 4/96:30 amBOS - STL

Nonstop3h 12mAmerican Airlines

Sun 4/136:13 amSTL - BOS

1 stop4h 00mAmerican Airlines

Deal found 4/1

$497

Wed 4/91:22 pmBGR - STL

3 stops30h 19mMultiple Airlines

Sun 4/136:10 pmSTL - BGR

2 stops22h 17mMultiple Airlines

Deal found 3/31

$633

Wed 4/93:55 pmBGR - STL

2 stops8h 34mDelta

Sun 4/136:10 amSTL - BGR

1 stop4h 43mDelta

Deal found 4/1

$667

Wed 4/92:00 pmBOS - STL

1 stop7h 51mDelta

Sun 4/137:12 pmSTL - BOS

1 stop4h 55mDelta

Deal found 3/30

$710

Wed 4/911:55 amBOS - STL

1 stop10h 55mUnited Airlines

Fri 4/118:00 amSTL - BOS

2 stops7h 22mUnited Airlines

Deal found 3/31

$713

Thu 4/107:20 amPWM - STL

1 stop8h 25mAmerican Airlines

Sun 4/137:33 amSTL - PWM

1 stop12h 32mAmerican Airlines

Deal found 3/31

$636

Thu 4/106:00 amPWM - STL

1 stop6h 03mUnited Airlines

Sun 4/1310:40 amSTL - PWM

2 stops11h 47mUnited Airlines

Deal found 3/31

$752

One-way flights from Maine to St. Louis
Search for one-way flight options from Maine to St. Louis. Find affordable one-way fares based on user searches. Data last updated April 1, 2025.

Tue 4/153:05 pmPWM - STL

1 stop9h 41mFrontier

Deal found 3/31

$114

Thu 5/296:00 amBOS - STL

1 stop7h 20mUnited Airlines

Deal found 3/31

$147

Wed 5/73:49 pmBOS - STL

3 stops29h 21mMultiple Airlines

Deal found 3/31

$148

Tue 6/37:05 amBOS - STL

Nonstop2h 55mSouthwest

Deal found 3/31

$152

Sat 6/147:59 pmBOS - STL

2 stops20h 23mSpirit Airlines

Deal found 3/31

$154

Wed 6/259:40 amBOS - STL

1 stop15h 09mFrontier

Deal found 3/31

$157

Sat 5/315:20 amBOS - STL

1 stop5h 15mDelta

Deal found 4/1

$162

Thu 5/83:50 pmBGR - STL

1 stop6h 08mAmerican Airlines

Deal found 3/31

$162

Thu 4/246:30 amBOS - STL

Nonstop3h 12mAmerican Airlines

Deal found 4/1

$172

Fri 6/276:30 amBOS - STL

1 stop6h 06mSun Country Air

Deal found 3/31

$218

Thu 5/87:24 pmBGR - STL

3 stops24h 17mMultiple Airlines

Deal found 3/31

$220

Fri 5/26:35 pmBOS - STL

2 stops30h 24mAlaska Airlines

Deal found 3/31

$227

Cheapflights Fare Finder

Use the filters below to find and compare flights from Maine to St. Louis that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

PortlandSt. Louis

PWM - STL

PWMSTL

Portland

Mon 5/12

9:30 pm-12:06 am

1 stop27h 36m

Lambert-St Louis

Thu 5/15

5:45 pm-8:40 pm

1 stop25h 55m

$208

PortlandSt. Louis

PWM - STL

PWMSTL

Portland

Wed 5/21

4:01 pm-8:58 pm

1 stop5h 57m

Lambert-St Louis

Wed 5/28

4:01 pm-11:55 pm

1 stop6h 54m

$285

PortlandSt. Louis

PWM - STL

PWMSTL

Portland

Wed 5/21

6:05 am-2:35 pm

2 stops9h 30m

Lambert-St Louis

Wed 5/28

6:00 am-12:57 pm

1 stop5h 57m

$290

BostonSt. Louis

BOS - STL

BOSSTL

Boston Logan Intl

Thu 5/8

5:42 pm-8:10 pm

3 stops27h 28m

Lambert-St Louis

Sun 5/11

10:10 am-10:51 pm

3 stops35h 41m

$323

BostonSt. Louis

BOS - STL

BOSSTL

Boston Logan Intl

Tue 5/20

7:05 am-9:00 am

Nonstop2h 55m

Lambert-St Louis

Sat 5/24

6:45 pm-10:15 pm

Nonstop2h 30m

$327

BostonSt. Louis

BOS - STL

BOSSTL

Boston Logan Intl

Wed 6/11

9:40 am-11:49 pm

1 stop15h 09m

Lambert-St Louis

Sun 6/15

8:44 pm-11:01 am

1 stop13h 17m

$331

BostonSt. Louis

BOS - STL

BOSSTL

Boston Logan Intl

Sat 4/19

6:50 pm-11:36 pm

1 stop5h 46m

Lambert-St Louis

Tue 4/22

6:08 am-12:18 pm

1 stop5h 10m

$332

BostonSt. Louis

BOS - STL

BOSSTL

Boston Logan Intl

Tue 5/20

6:30 am-8:40 am

Nonstop3h 10m

Lambert-St Louis

Sat 5/24

6:20 am-1:56 pm

1 stop6h 36m

$337

BostonSt. Louis

BOS - STL

BOSSTL

Boston Logan Intl

Mon 5/5

10:45 am-2:47 pm

1 stop5h 02m

Lambert-St Louis

Wed 5/7

6:30 am-2:19 pm

2 stops6h 49m

$363

BostonSt. Louis

BOS - STL

BOSSTL

Boston Logan Intl

Thu 5/1

11:39 am-11:31 am

1 stop24h 52m

Lambert-St Louis

Sun 5/4

8:00 am-11:04 pm

1 stop14h 04m

$370

Flights are sorted by cheapest round-trip flights first.

Deals found on 3/31

Showing 1-10 of 36 results

Best time to book a flight from Maine to St. Louis

Have a flexible travel schedule? Discover the best time to fly to St. Louis from Maine with our price prediction graph.

Estimated round-trip price

Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Maine to St. Louis

What is the cheapest month to book a flight from Maine to St. Louis?

Currently, August is the cheapest month in which you can book a flight from Maine to St. Louis (average of $311). Flying from Maine to St. Louis in March is currently the most expensive (average of $356). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from ME to STL?

When flying from Maine to St. Louis, the time of day you decide to fly out makes little to no difference towards the overall price you’ll pay on tickets.

Rainfall in St. Louis by month

In terms of precipitation, rainfall in St. Louis ranges from 2.2 - 4.7 inches per month. May is typically the wettest month, when rainfall can reach 4.7 in. February is typically the driest time to visit St. Louis when rainfall is around 2.2 in.

Temperature in St. Louis by month

If weather is an important factor for your trip to St. Louis, use this chart to help with planning. For those seeking warmer temperatures, July is the ideal time of year to visit, when temperatures reach an average of 80.6 F. Travelers looking to avoid the cold should look outside of January, when temperatures are typically at their lowest (around 32.0 F).

Reviews of airlines servicing St. Louis

See what other customers who have flown with Alaska Airlines, Southwest and Delta from Maine to St. Louis have to say. Users can see the overall rating for each airline as well as how each is rated in terms of entertainment options, comfort, food, crew/service, and boarding process.

Alaska Airlines

8.0

Very good

9,823 reviews

Reviews

1 / 20

10.0

Excellent

Cheri,Jan 2025

FAT - SEA

Very friendly. I really liked that they had water for us in cartons not plastic. Impressed with Alaska Airlines, First time I had flown them

Alaska Airlines

8.0

Very good

9,823 reviews

Alaska Airlines

8.0

Very good

9,823 reviews

Reviews

1 / 20

10.0

Excellent

Cheri,Jan 2025

FAT - SEA

Very friendly. I really liked that they had water for us in cartons not plastic. Impressed with Alaska Airlines, First time I had flown them

Southwest

8.0

Very good

4,275 reviews

Alaska Airlines

8.0

Very good

9,823 reviews

Reviews

1 / 20

10.0

Excellent

Cheri,Jan 2025

FAT - SEA

Very friendly. I really liked that they had water for us in cartons not plastic. Impressed with Alaska Airlines, First time I had flown them

Delta

8.0

Very good

7,899 reviews

Alaska Airlines

8.0

Very good

9,823 reviews

Reviews

1 / 20

10.0

Excellent

Cheri,Jan 2025

FAT - SEA

Very friendly. I really liked that they had water for us in cartons not plastic. Impressed with Alaska Airlines, First time I had flown them

United Airlines

7.4

Good

8,615 reviews

Alaska Airlines

8.0

Very good

9,823 reviews

Reviews

1 / 20

10.0

Excellent

Cheri,Jan 2025

FAT - SEA

Very friendly. I really liked that they had water for us in cartons not plastic. Impressed with Alaska Airlines, First time I had flown them

American Airlines

7.2

Good

10,000 reviews

Alaska Airlines

8.0

Very good

9,823 reviews

Reviews

1 / 20

10.0

Excellent

Cheri,Jan 2025

FAT - SEA

Very friendly. I really liked that they had water for us in cartons not plastic. Impressed with Alaska Airlines, First time I had flown them

Related info for your journey

What airport do you fly into for flights to St. Louis from Maine?
If you book a flight to St. Louis from Maine, you will be flying to Lambert-St Louis, which is the city’s only airport. Lambert-St Louis (STL) is located 12.7 mi from the center of St. Louis.
What are the cheapest airlines to fly from Maine to St. Louis one-way?
One-way options have recently been found by users for as low as $114 on Frontier. Other airlines that offer cheap prices include United Airlines from $147 and Southwest from $152 one-way.
What are the most popular routes from Maine to St. Louis?
Most travelers choose Boston Logan Intl - Lambert-St Louis, Portland - Lambert-St Louis or Bangor - Lambert-St Louis when deciding on the best route from Maine to St. Louis.
Can I find deals for flights from Maine to St. Louis that include hotel bookings?
Yes. In addition to deals on Maine to St. Louis flights, Cheapflights offers vacation packages that include both flights and hotel.
How can I find direct flights from Maine to St. Louis?
After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Maine to St. Louis.
Can I find deals for business class flights from Maine to St. Louis?
Yes. Cheapflights offers flight deals from Maine to St. Louis by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.
What is the cheapest month to book a flight from Maine to St. Louis?
Currently, August is the cheapest month in which you can book a flight from Maine to St. Louis (average of $311). Flying from Maine to St. Louis in March is currently the most expensive (average of $356). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Fenton

Maryland Heights

Fairview Heights

Collinsville

Wentzville

Eureka

St. Peters

Festus

Glencoe

Alton

Farmington

Chesterfield

Browse thousands of different options on Cheapflights for your next trip

Top 4 airlines flying from Maine to St. Louis

Airline	Cheapest	Average	Flexibility	On-time
American Airlines	Cheapest$258	Average$418	FlexibilityNo cancel fee	On-time71%
Delta	Cheapest$273	Average$430	FlexibilityNo cancel fee	On-timeN/A
United Airlines	Cheapest$341	Average$478	FlexibilityNo cancel fee	On-time69%
Southwest	Cheapest$351	Average$417	FlexibilityNo cancel fee	On-time63%

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$114+ Cheap flights from Maine to St. Louis (STL)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 4/15. Fares are subject to change and may not be available on all flights or dates of travel.

Find cheap flights from Maine to St. Louis with Cheapflights

1. Tell us where you want to go

2. Select your favorite providers

3. Compare prices and book

Cheap flight deals from Maine to St. Louis

Keep the following information in mind while searching for Maine to St. Louis flight deals. Data was last updated April 1, 2025.

Most accurate provider

Most trusted provider

Round-trip from

One-way from

Popular in

Cheapest in

Average price

Find flight deals from Maine to St. Louis

Cheapest flights from Maine to St. LouisExplore the most affordable flight options available from Maine to St. Louis. Find the lowest fares from popular airlines and budget airlines, with prices last updated on April 1, 2025.

Explore the most affordable flight options available from Maine to St. Louis. Find the lowest fares from popular airlines and budget airlines, with prices last updated on April 1, 2025.

Cheapflights Fare Finder

Use the filters below to find and compare flights from Maine to St. Louis that are best for you.

Best time to book a flight from Maine to St. Louis

Have a flexible travel schedule? Discover the best time to fly to St. Louis from Maine with our price prediction graph.

Cheapflights Insights

Everything you need to know about your flight from Maine to St. Louis

What is the cheapest month to book a flight from Maine to St. Louis?

What is the cheapest time of day to fly from ME to STL?

Find hourly flight availability from Maine to St. Louis. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated April 1, 2025.

Rainfall in St. Louis by month

Plan your trip to St. Louis by taking into account the average rainfall totals by month.

Temperature in St. Louis by month

Plan your trip to St. Louis by taking into account the average temperature totals by month.

Reviews of airlines servicing St. Louis

See what other customers who have flown with Alaska Airlines, Southwest and Delta from Maine to St. Louis have to say. Users can see the overall rating for each airline as well as how each is rated in terms of entertainment options, comfort, food, crew/service, and boarding process.

Related info for your journey

Find useful and relevant information for your journey from Maine to St. Louis. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

What airport do you fly into for flights to St. Louis from Maine?

What are the cheapest airlines to fly from Maine to St. Louis one-way?

What are the most popular routes from Maine to St. Louis?

Can I find deals for flights from Maine to St. Louis that include hotel bookings?

How can I find direct flights from Maine to St. Louis?

Can I find deals for business class flights from Maine to St. Louis?

What is the cheapest month to book a flight from Maine to St. Louis?

Traveling to a place near Maine?

Browse thousands of different options on Cheapflights for your next trip

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Alternative routes for Maine to St. Louis

See prices for flight routes from nearby airports that may be better suited for you.

Top 4 airlines flying from Maine to St. Louis

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Cheapest flights from Maine to St. Louis
Explore the most affordable flight options available from Maine to St. Louis. Find the lowest fares from popular airlines and budget airlines, with prices last updated on April 1, 2025.