What are the cheapest airlines to fly from Maine to St. Louis one-way?

One-way options have recently been found by users for as low as $106 on Frontier. Other airlines that offer cheap prices include American Airlines from $152 and United Airlines from $156 one-way.

What are the most popular routes from Maine to St. Louis?

Most travelers choose Boston Logan Intl - Lambert-St Louis, Portland - Lambert-St Louis or Bangor - Lambert-St Louis when deciding on the best route from Maine to St. Louis.

What are the most popular airlines that fly from Maine to St. Louis?

Consider American Airlines, Delta or United Airlines when booking your flight. These represent the most popular airlines when flying from Maine to St. Louis.

How far in advance should I book a flight from Maine to St. Louis?

Travelers have found it’s best to book a flight 11 days in advance to save up to 145% compared to booking the same week of travel. As your travel date approaches, the cost of this flight route may potentially increase. While opting to book 11 days out may not be an option for all, there are still additional ways to secure a deal in the near future. You might find a flight from Maine to St. Louis 1-2 weeks in advance for as low as $228, or $639 for flights within the next 24 hours.

What is the cheapest month to fly from Maine to St. Louis?

Our data shows that February tends to be the cheapest month to fly to St. Louis from Maine. Users have commonly found prices around $427 for the month, but tickets can be as low as $213. Due to multiple factors, prepare for potentially higher prices in December.

What airport do you fly into for flights to St. Louis from Maine?

If you book a flight to St. Louis from Maine, you will be flying to Lambert-St Louis, which is the city’s only airport. Lambert-St Louis (STL) is located 12.7 mi from the center of St. Louis.

Can I find deals for flights from Maine to St. Louis that include hotel bookings?

Yes. In addition to deals on Maine to St. Louis flights, Cheapflights offers vacation packages that include both flights and hotel.

How can I find direct flights from Maine to St. Louis?

After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Maine to St. Louis.

Can I find deals for business class flights from Maine to St. Louis?

Yes. Cheapflights offers flight deals from Maine to St. Louis by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

$106+ Flights from Maine to St. Louis

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Cheap flight deals from Maine to St. Louis

Most accurate provider	Mytrip 3 stars
Most trusted provider	Mytrip 3 stars
Round-trip from	$198 (Mytrip)
One-way from	$106 (Mytrip)
Popular in	December
Cheapest in	February
Average price	$526

Provider with most accurate pricing for Portland-Lambert-St Louis flight deals.

Search Deals

Provider most trusted by Cheapflights users for Portland-Lambert-St Louis flights.

Search Deals

From Maine to Lambert-St Louis

Search Deals

One-way flight from Maine to Lambert-St Louis

Search Deals

Highest demand for flights based on searches. 4% potential increase in price ($17 potential increase over avg. RT price).

Search Deals

Cheapest flight prices on average. 2% potential price decrease ($11 potential savings vs. average RT price).

Search Deals

Average for round-trip flights in April 2025

Search Deals

Find flight deals from Maine to St. Louis

Cheapest flights from Maine to St. Louis
Explore the most affordable flight options available from Maine to St. Louis. Find the lowest fares from popular airlines and budget airlines, with prices last updated on avril 22, 2025.

lun. 4/288:11 pmPWM - STL

1 stop28h 53mFrontier

mer. 4/305:41 pmSTL - PWM

1 stop25h 48mFrontier

Deal found 4/21

$198

mer. 5/215:50 amPWM - STL

1 stop4h 52mAmerican Airlines

mer. 5/286:00 amSTL - PWM

1 stop4h 32mAmerican Airlines

Deal found 4/21

$285

mer. 5/216:05 amPWM - STL

2 stops9h 30mDelta

mer. 5/285:40 pmSTL - PWM

1 stop5h 19mDelta

Deal found 4/21

$290

mar. 6/245:43 pmBGR - STL

1 stop7h 11mAmerican Airlines

mer. 7/25:30 amSTL - BGR

1 stop7h 15mAmerican Airlines

Deal found 4/22

$323

jeu. 6/268:56 pmPWM - STL

2 stops21h 08mMultiple Airlines

dim. 6/296:12 amSTL - PWM

1 stop28h 11mMultiple Airlines

Deal found 4/21

$329

jeu. 6/196:00 amBOS - STL

2 stops12h 04mSpirit Airlines

dim. 6/226:12 pmSTL - BOS

1 stop13h 27mSpirit Airlines

Deal found 4/22

$331

lun. 5/126:30 amBOS - STL

Nonstop3h 10mAmerican Airlines

dim. 5/256:00 amSTL - BOS

1 stop5h 12mAmerican Airlines

Deal found 4/21

$333

ven. 6/610:51 amBOS - STL

1 stop13h 46mMultiple Airlines

lun. 6/97:00 amSTL - BOS

1 stop26h 37mMultiple Airlines

Deal found 4/22

$334

sam. 5/245:55 pmBOS - STL

Nonstop3h 05mSouthwest

lun. 5/269:10 pmSTL - BOS

1 stop10h 00mSouthwest

Deal found 4/22

$339

mer. 5/215:40 amBOS - STL

1 stop7h 24mDelta

sam. 5/245:17 pmSTL - BOS

1 stop4h 39mDelta

Deal found 4/22

$343

mer. 5/216:00 amBOS - STL

1 stop9h 47mUnited Airlines

mer. 5/286:30 amSTL - BOS

2 stops7h 55mUnited Airlines

Deal found 4/22

$348

dim. 10/194:00 pmBGR - STL

1 stop8h 44mUnited Airlines

mer. 10/2212:28 pmSTL - BGR

1 stop8h 12mUnited Airlines

Deal found 4/22

$352

Best flights from Maine to St. Louis
Discover carefully curated flight deals from Maine to St. Louis that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated avril 22, 2025.

lun. 4/288:11 pmPWM - STL

1 stop28h 53mFrontier

mer. 4/305:41 pmSTL - PWM

1 stop25h 48mFrontier

Deal found 4/21

$198

mer. 5/215:50 amPWM - STL

1 stop4h 52mAmerican Airlines

mer. 5/286:00 amSTL - PWM

1 stop4h 32mAmerican Airlines

Deal found 4/21

$285

mer. 5/216:05 amPWM - STL

2 stops9h 30mDelta

mer. 5/285:40 pmSTL - PWM

1 stop5h 19mDelta

Deal found 4/21

$290

jeu. 6/268:56 pmPWM - STL

2 stops21h 08mMultiple Airlines

dim. 6/296:12 amSTL - PWM

1 stop28h 11mMultiple Airlines

Deal found 4/21

$329

jeu. 6/196:00 amBOS - STL

2 stops12h 04mSpirit Airlines

dim. 6/226:12 pmSTL - BOS

1 stop13h 27mSpirit Airlines

Deal found 4/22

$331

sam. 5/245:55 pmBOS - STL

Nonstop3h 05mSouthwest

lun. 5/269:10 pmSTL - BOS

1 stop10h 00mSouthwest

Deal found 4/22

$339

mer. 5/216:00 amBOS - STL

1 stop9h 47mUnited Airlines

mer. 5/286:30 amSTL - BOS

2 stops7h 55mUnited Airlines

Deal found 4/22

$348

jeu. 6/2612:40 pmPWM - STL

1 stop23h 56mSun Country Air

dim. 6/296:12 amSTL - PWM

1 stop28h 11mSun Country Air

Deal found 4/21

$372

mar. 6/245:43 pmBGR - STL

1 stop7h 11mAmerican Airlines

mer. 7/25:30 amSTL - BGR

1 stop7h 15mAmerican Airlines

Deal found 4/22

$323

ven. 6/610:51 amBOS - STL

1 stop13h 46mMultiple Airlines

lun. 6/97:00 amSTL - BOS

1 stop26h 37mMultiple Airlines

Deal found 4/22

$334

lun. 5/128:00 amBOS - STL

1 stop7h 35mDelta

mar. 5/279:00 amSTL - BOS

1 stop5h 14mDelta

Deal found 4/21

$336

dim. 10/194:00 pmBGR - STL

1 stop8h 44mUnited Airlines

mer. 10/2212:28 pmSTL - BGR

1 stop8h 12mUnited Airlines

Deal found 4/22

$352

Last-minute flights from Maine to St. Louis
Discover last-minute flight deals from Maine to St. Louis. Data last updated avril 22, 2025 and is based on user searches.

lun. 4/288:11 pmPWM - STL

1 stop28h 53mFrontier

mer. 4/305:41 pmSTL - PWM

1 stop25h 48mFrontier

Deal found 4/21

$198

lun. 4/286:15 amPWM - STL

2 stops10h 32mUnited Airlines

mer. 4/303:40 pmSTL - PWM

1 stop4h 55mUnited Airlines

Deal found 4/21

$603

mar. 4/295:00 amBOS - STL

1 stop7h 24mAmerican Airlines

mar. 4/292:19 pmSTL - BOS

Nonstop2h 43mAmerican Airlines

Deal found 4/22

$340

mar. 4/2912:15 pmPWM - STL

1 stop9h 32mAmerican Airlines

ven. 5/95:12 amSTL - PWM

1 stop6h 27mAmerican Airlines

Deal found 4/21

$510

mar. 4/295:32 amPWM - STL

2 stops11h 54mDelta

ven. 5/96:00 amSTL - PWM

1 stop5h 57mDelta

Deal found 4/21

$532

mar. 4/296:00 amBOS - STL

2 stops12h 15mSpirit Airlines

jeu. 5/16:10 pmSTL - BOS

1 stop26h 49mSpirit Airlines

Deal found 4/22

$538

mer. 4/307:10 amBOS - STL

1 stop15h 40mUnited Airlines

sam. 5/34:45 pmSTL - BOS

1 stop11h 54mUnited Airlines

Deal found 4/22

$593

jeu. 5/111:39 amBOS - STL

1 stop24h 52mSun Country Air

dim. 5/48:00 amSTL - BOS

1 stop25h 42mSun Country Air

Deal found 4/22

$375

jeu. 5/19:09 pmBOS - STL

3 stops22h 32mMultiple Airlines

sam. 5/39:50 amSTL - BOS

2 stops7h 53mMultiple Airlines

Deal found 4/22

$381

jeu. 5/12:30 pmPWM - STL

2 stops8h 30mSouthwest

sam. 5/36:30 amSTL - PWM

1 stop4h 35mSouthwest

Deal found 4/22

$682

ven. 5/25:20 pmBOS - STL

2 stops17h 08mDelta

mar. 5/65:37 pmSTL - BOS

2 stops15h 30mDelta

Deal found 4/22

$484

ven. 5/27:35 amBOS - STL

Nonstop2h 55mSouthwest

mar. 5/68:15 amSTL - BOS

Nonstop2h 35mSouthwest

Deal found 4/22

$636

One-way flights from Maine to St. Louis
Search for one-way flight options from Maine to St. Louis. Find affordable one-way fares based on user searches. Data last updated avril 22, 2025.

dim. 5/188:23 pmPWM - STL

1 stop28h 43mFrontier

Deal found 4/22

$106

sam. 5/2411:46 amBOS - STL

Nonstop3h 04mAmerican Airlines

Deal found 4/22

$152

sam. 6/76:00 amBOS - STL

1 stop7h 20mUnited Airlines

Deal found 4/22

$156

mer. 6/112:25 pmBOS - STL

3 stops27h 39mSpirit Airlines

Deal found 4/22

$157

dim. 5/259:10 amBOS - STL

1 stop6h 25mDelta

Deal found 4/21

$162

mar. 5/203:49 pmBOS - STL

3 stops44h 56mMultiple Airlines

Deal found 4/20

$163

mar. 7/15:45 amBOS - STL

2 stops6h 50mSouthwest

Deal found 4/22

$167

dim. 5/116:05 amPWM - STL

2 stops11h 30mDelta

Deal found 4/21

$229

sam. 7/55:45 pmBGR - STL

1 stop7h 04mAmerican Airlines

Deal found 4/22

$250

dim. 5/113:17 pmPWM - STL

3 stops28h 24mMultiple Airlines

Deal found 4/21

$297

ven. 6/64:49 pmBOS - STL

2 stops22h 18mAlaska Airlines

Deal found 4/22

$307

sam. 7/56:00 amBGR - STL

2 stops9h 37mDelta

Deal found 4/22

$316

Cheapflights Fare Finder

Use the filters below to find and compare flights from Maine to St. Louis that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

PortlandSt. Louis

PWM - STL

PWMSTL

Portland

lun. 4/28

8:11 pm-12:04 am

1 stop28h 53m

Lambert-St Louis

mer. 4/30

5:41 pm-8:29 pm

1 stop25h 48m

$198

PortlandSt. Louis

PWM - STL

PWMSTL

Portland

mer. 5/21

5:50 am-9:42 am

1 stop4h 52m

Lambert-St Louis

mer. 5/28

6:00 am-11:32 am

1 stop4h 32m

$285

PortlandSt. Louis

PWM - STL

PWMSTL

Portland

mer. 5/21

6:05 am-2:35 pm

2 stops9h 30m

Lambert-St Louis

mer. 5/28

5:40 pm-11:59 pm

1 stop5h 19m

$290

BangorSt. Louis

BGR - STL

BGRSTL

Bangor

mar. 6/24

5:43 pm-11:54 pm

1 stop7h 11m

Lambert-St Louis

mer. 7/2

5:30 am-1:45 pm

1 stop7h 15m

$323

PortlandSt. Louis

PWM - STL

PWMSTL

Portland

jeu. 6/26

8:56 pm-5:04 pm

2 stops21h 08m

Lambert-St Louis

dim. 6/29

6:12 am-11:23 am

1 stop28h 11m

$329

BostonSt. Louis

BOS - STL

BOSSTL

Boston Logan Intl

jeu. 6/19

6:00 am-5:04 pm

2 stops12h 04m

Lambert-St Louis

dim. 6/22

6:12 pm-8:39 am

1 stop13h 27m

$331

BostonSt. Louis

BOS - STL

BOSSTL

Boston Logan Intl

lun. 5/12

6:30 am-8:40 am

Nonstop3h 10m

Lambert-St Louis

dim. 5/25

6:00 am-12:12 pm

1 stop5h 12m

$333

BostonSt. Louis

BOS - STL

BOSSTL

Boston Logan Intl

ven. 6/6

10:51 am-11:37 pm

1 stop13h 46m

Lambert-St Louis

lun. 6/9

7:00 am-10:37 am

1 stop26h 37m

$334

BostonSt. Louis

BOS - STL

BOSSTL

Boston Logan Intl

sam. 5/24

5:55 pm-8:00 pm

Nonstop3h 05m

Lambert-St Louis

lun. 5/26

9:10 pm-8:10 am

1 stop10h 00m

$339

BostonSt. Louis

BOS - STL

BOSSTL

Boston Logan Intl

mer. 5/21

5:40 am-12:04 pm

1 stop7h 24m

Lambert-St Louis

sam. 5/24

5:17 pm-10:56 pm

1 stop4h 39m

$343

Flights are sorted by cheapest round-trip flights first.

Deals found on 4/22

Showing 1-10 of 32 results

Best time to book a flight from Maine to St. Louis

Have a flexible travel schedule? Discover the best time to fly to St. Louis from Maine with our price prediction graph.

Estimated round-trip price

Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Maine to St. Louis

What is the cheapest month to book a flight from Maine to St. Louis?

Currently, August is the cheapest month in which you can book a flight from Maine to St. Louis (average of $311). Flying from Maine to St. Louis in March is currently the most expensive (average of $356). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from ME to STL?

When flying from Maine to St. Louis, the time of day you decide to fly out makes little to no difference towards the overall price you’ll pay on tickets.

Rainfall in St. Louis by month

In terms of precipitation, rainfall in St. Louis ranges from 2.2 - 4.7 inches per month. May is typically the wettest month, when rainfall can reach 4.7 in. February is typically the driest time to visit St. Louis when rainfall is around 2.2 in.

Temperature in St. Louis by month

If weather is an important factor for your trip to St. Louis, use this chart to help with planning. For those seeking warmer temperatures, July is the ideal time of year to visit, when temperatures reach an average of 80.6 F. Travelers looking to avoid the cold should look outside of January, when temperatures are typically at their lowest (around 32.0 F).

Reviews of airlines servicing St. Louis

See what other customers who have flown with Alaska Airlines, Southwest and Delta from Maine to St. Louis have to say. Users can see the overall rating for each airline as well as how each is rated in terms of entertainment options, comfort, food, crew/service, and boarding process.

Alaska Airlines

8.0

Very good

9,911 reviews

Reviews

1 / 20

4.0

Okay

Anonymous,Apr 2025

LAS - STS

flight was delayed both ways even tho the weather was clear >

Alaska Airlines

8.0

Very good

9,911 reviews

Alaska Airlines

8.0

Very good

9,911 reviews

Reviews

1 / 20

4.0

Okay

Anonymous,Apr 2025

LAS - STS

flight was delayed both ways even tho the weather was clear >

Southwest

8.0

Very good

4,287 reviews

Alaska Airlines

8.0

Very good

9,911 reviews

Reviews

1 / 20

4.0

Okay

Anonymous,Apr 2025

LAS - STS

flight was delayed both ways even tho the weather was clear >

Delta

8.0

Very good

7,920 reviews

Alaska Airlines

8.0

Very good

9,911 reviews

Reviews

1 / 20

4.0

Okay

Anonymous,Apr 2025

LAS - STS

flight was delayed both ways even tho the weather was clear >

United Airlines

7.4

Good

8,683 reviews

Alaska Airlines

8.0

Very good

9,911 reviews

Reviews

1 / 20

4.0

Okay

Anonymous,Apr 2025

LAS - STS

flight was delayed both ways even tho the weather was clear >

American Airlines

7.2

Good

10,000 reviews

Alaska Airlines

8.0

Very good

9,911 reviews

Reviews

1 / 20

4.0

Okay

Anonymous,Apr 2025

LAS - STS

flight was delayed both ways even tho the weather was clear >

Related info for your journey

What airport do you fly into for flights to St. Louis from Maine?
If you book a flight to St. Louis from Maine, you will be flying to Lambert-St Louis, which is the city’s only airport. Lambert-St Louis (STL) is located 12.7 mi from the center of St. Louis.
What are the cheapest airlines to fly from Maine to St. Louis one-way?
One-way options have recently been found by users for as low as $106 on Frontier. Other airlines that offer cheap prices include American Airlines from $152 and United Airlines from $156 one-way.
What are the most popular routes from Maine to St. Louis?
Most travelers choose Boston Logan Intl - Lambert-St Louis, Portland - Lambert-St Louis or Bangor - Lambert-St Louis when deciding on the best route from Maine to St. Louis.
Can I find deals for flights from Maine to St. Louis that include hotel bookings?
Yes. In addition to deals on Maine to St. Louis flights, Cheapflights offers vacation packages that include both flights and hotel.
How can I find direct flights from Maine to St. Louis?
After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Maine to St. Louis.
Can I find deals for business class flights from Maine to St. Louis?
Yes. Cheapflights offers flight deals from Maine to St. Louis by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.
What is the cheapest month to book a flight from Maine to St. Louis?
Currently, August is the cheapest month in which you can book a flight from Maine to St. Louis (average of $311). Flying from Maine to St. Louis in March is currently the most expensive (average of $356). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Fenton

Maryland Heights

Fairview Heights

Collinsville

Wentzville

Eureka

St. Peters

Festus

Glencoe

Alton

Farmington

Browse thousands of different options on Cheapflights for your next trip

Top 4 airlines flying from Maine to St. Louis

Airline	Cheapest	Average	Flexibility	On-time
American Airlines	Cheapest$241	Average$406	FlexibilityNo cancel fee	On-time71%
Delta	Cheapest$273	Average$414	FlexibilityNo cancel fee	On-timeN/A
United Airlines	Cheapest$341	Average$466	FlexibilityNo cancel fee	On-time69%
Southwest	Cheapest$351	Average$417	FlexibilityNo cancel fee	On-time63%

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$106+ Cheap flights from Maine to St. Louis (STL)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 5/18. Fares are subject to change and may not be available on all flights or dates of travel.

Find cheap flights from Maine to St. Louis with Cheapflights

1. Tell us where you want to go

2. Select your favorite providers

3. Compare prices and book

Cheap flight deals from Maine to St. Louis

Keep the following information in mind while searching for Maine to St. Louis flight deals. Data was last updated avril 22, 2025.

Most accurate provider

Most trusted provider

Round-trip from

One-way from

Popular in

Cheapest in

Average price

Find flight deals from Maine to St. Louis

Cheapest flights from Maine to St. LouisExplore the most affordable flight options available from Maine to St. Louis. Find the lowest fares from popular airlines and budget airlines, with prices last updated on avril 22, 2025.

Explore the most affordable flight options available from Maine to St. Louis. Find the lowest fares from popular airlines and budget airlines, with prices last updated on avril 22, 2025.

Cheapflights Fare Finder

Use the filters below to find and compare flights from Maine to St. Louis that are best for you.

Best time to book a flight from Maine to St. Louis

Have a flexible travel schedule? Discover the best time to fly to St. Louis from Maine with our price prediction graph.

Cheapflights Insights

Everything you need to know about your flight from Maine to St. Louis

What is the cheapest month to book a flight from Maine to St. Louis?

What is the cheapest time of day to fly from ME to STL?

Find hourly flight availability from Maine to St. Louis. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated avril 22, 2025.

Rainfall in St. Louis by month

Plan your trip to St. Louis by taking into account the average rainfall totals by month.

Temperature in St. Louis by month

Plan your trip to St. Louis by taking into account the average temperature totals by month.

Reviews of airlines servicing St. Louis

See what other customers who have flown with Alaska Airlines, Southwest and Delta from Maine to St. Louis have to say. Users can see the overall rating for each airline as well as how each is rated in terms of entertainment options, comfort, food, crew/service, and boarding process.

Related info for your journey

Find useful and relevant information for your journey from Maine to St. Louis. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

What airport do you fly into for flights to St. Louis from Maine?

What are the cheapest airlines to fly from Maine to St. Louis one-way?

What are the most popular routes from Maine to St. Louis?

Can I find deals for flights from Maine to St. Louis that include hotel bookings?

How can I find direct flights from Maine to St. Louis?

Can I find deals for business class flights from Maine to St. Louis?

What is the cheapest month to book a flight from Maine to St. Louis?

Traveling to a place near Maine?

Browse thousands of different options on Cheapflights for your next trip

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Alternative routes for Maine to St. Louis

See prices for flight routes from nearby airports that may be better suited for you.

Top 4 airlines flying from Maine to St. Louis

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Cheapest flights from Maine to St. Louis
Explore the most affordable flight options available from Maine to St. Louis. Find the lowest fares from popular airlines and budget airlines, with prices last updated on avril 22, 2025.