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$49+ Cheap flights from Iowa to St. Louis (STL)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 6/17. Fares are subject to change and may not be available on all flights or dates of travel.
DSM — STL
Apr 22 — Apr 291
Tue 4/22
Tue 4/29
1 adult, Economy
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Cheap flight deals from Iowa to St. Louis

Keep the following information in mind while searching for Iowa to St. Louis flight deals. Data was last updated April 17, 2025.

Most accurate provider

FlightHub
3 stars

Most trusted provider

eDreams
3 stars

Round-trip from

$252
(Delta)

One-way from

$49
(Southwest)

Popular in

September

Cheapest in

August

Average price

$309

Good round-trip deal

$339 or less

Good one-way deal

$163 or less
Provider with most accurate pricing for Des Moines-Lambert-St Louis flight deals.
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Provider most trusted by Cheapflights users for Des Moines-Lambert-St Louis flights.
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From Iowa to Lambert-St Louis
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One-way flight from Iowa to Lambert-St Louis
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Highest demand for flights based on searches. 9% potential increase in price ($39 potential increase over avg. RT price).
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Cheapest flight prices on average. 7% potential price decrease ($26 potential savings vs. average RT price).
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Average for round-trip flights in April 2025
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Price to beat on a round-trip flight from Iowa to Lambert-St Louis.
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Price to beat on a one-way flight from Iowa to Lambert-St Louis.
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Find flight deals from Iowa to St. Louis

Cheapest flights from Iowa to St. Louis
Explore the most affordable flight options available from Iowa to St. Louis. Find the lowest fares from popular airlines and budget airlines, with prices last updated on April 17, 2025.

This Booking.com deal was found by Cheapflights users on 4/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Booking.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/127:51 pmOMA - STL
1 stop13h 20mFrontier
Sat 8/167:29 pmSTL - OMA
1 stop23h 24mFrontier
Deal found 4/17$193
This Delta deal was found by Cheapflights users on 4/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/95:30 pmDSM - STL
1 stop5h 56mDelta
Sun 5/116:00 amSTL - DSM
1 stop6h 27mDelta
Deal found 4/16$252
This Southwest deal was found by Cheapflights users on 4/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 6/36:00 amOMA - STL
Nonstop1h 15mSouthwest
Thu 6/59:30 amSTL - OMA
Nonstop1h 15mSouthwest
Deal found 4/17$256
This American Airlines deal was found by Cheapflights users on 4/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/155:32 amDSM - STL
1 stop16h 20mAmerican Airlines
Thu 5/225:00 amSTL - DSM
1 stop18h 39mAmerican Airlines
Deal found 4/17$275
This United Airlines deal was found by Cheapflights users on 4/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/711:30 amOMA - STL
1 stop4h 17mUnited Airlines
Fri 5/95:29 pmSTL - OMA
1 stop3h 54mUnited Airlines
Deal found 4/15$281
This Southwest deal was found by Cheapflights users on 4/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/126:00 amDSM - STL
Nonstop1h 05mSouthwest
Sun 9/1410:40 pmSTL - DSM
Nonstop1h 10mSouthwest
Deal found 4/16$286
This American Airlines deal was found by Cheapflights users on 4/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/1612:43 pmOMA - STL
1 stop6h 46mAmerican Airlines
Sun 5/185:19 amSTL - OMA
1 stop6h 34mAmerican Airlines
Deal found 4/16$331
This Mytrip deal was found by Cheapflights users on 4/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/1611:41 amOMA - STL
2 stops21h 34mMultiple Airlines
Sun 5/187:30 amSTL - OMA
2 stops27h 21mMultiple Airlines
Deal found 4/16$377
This Mytrip deal was found by Cheapflights users on 4/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 6/156:32 pmDSM - STL
2 stops24h 09mMultiple Airlines
Fri 6/279:50 amSTL - DSM
2 stops8h 21mMultiple Airlines
Deal found 4/17$378
This United Airlines deal was found by Cheapflights users on 4/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/28:07 amDSM - STL
1 stop6h 40mUnited Airlines
Sun 5/45:29 pmSTL - DSM
1 stop4h 23mUnited Airlines
Deal found 4/17$393
This American Airlines deal was found by Cheapflights users on 4/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/111:47 amLSE - STL
1 stop4h 24mAmerican Airlines
Mon 5/56:45 amSTL - LSE
1 stop4h 34mAmerican Airlines
Deal found 4/16$520
This Alaska Airlines deal was found by Cheapflights users on 4/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Alaska Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/73:25 pmOMA - STL
2 stops17h 34mAlaska Airlines
Fri 5/92:18 pmSTL - OMA
2 stops24h 11mAlaska Airlines
Deal found 4/15$753

Cheapflights Fare Finder

Customize your flight search to find flights from Iowa to St. Louis that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated April 17, 2025.
Use the filters below to find and compare flights from Iowa to St. Louis that are best for you.

Fly from

Iowa

Fly to

St. Louis

Route

Depart

Return

Price

OmahaSt. Louis

OMA - STL

OMASTL

Omaha Eppley Airfield

Tue 8/12

7:51 pm-9:11 am

1 stop13h 20m

Lambert-St Louis

Sat 8/16

7:29 pm-6:53 pm

1 stop23h 24m

$193

Des MoinesSt. Louis

DSM - STL

DSMSTL

Des Moines

Fri 5/9

5:30 pm-11:26 pm

1 stop5h 56m

Lambert-St Louis

Sun 5/11

6:00 am-12:27 pm

1 stop6h 27m

$252

OmahaSt. Louis

OMA - STL

OMASTL

Omaha Eppley Airfield

Tue 6/3

6:00 am-7:15 am

Nonstop1h 15m

Lambert-St Louis

Thu 6/5

9:30 am-10:45 am

Nonstop1h 15m

$256

Des MoinesSt. Louis

DSM - STL

DSMSTL

Des Moines

Thu 5/15

5:32 am-9:52 pm

1 stop16h 20m

Lambert-St Louis

Thu 5/22

5:00 am-11:39 pm

1 stop18h 39m

$275

Des MoinesSt. Louis

DSM - STL

DSMSTL

Des Moines

Fri 9/12

6:00 am-7:05 am

Nonstop1h 05m

Lambert-St Louis

Sun 9/14

10:40 pm-11:50 pm

Nonstop1h 10m

$286

OmahaSt. Louis

OMA - STL

OMASTL

Omaha Eppley Airfield

Wed 7/9

11:28 am-3:47 pm

1 stop4h 19m

Lambert-St Louis

Mon 7/14

8:00 am-2:22 pm

1 stop6h 22m

$316

OmahaSt. Louis

OMA - STL

OMASTL

Omaha Eppley Airfield

Fri 5/16

12:43 pm-7:29 pm

1 stop6h 46m

Lambert-St Louis

Sun 5/18

5:19 am-11:53 am

1 stop6h 34m

$331

OmahaSt. Louis

OMA - STL

OMASTL

Omaha Eppley Airfield

Fri 5/16

11:41 am-9:15 am

2 stops21h 34m

Lambert-St Louis

Sun 5/18

7:30 am-10:51 am

2 stops27h 21m

$377

Des MoinesSt. Louis

DSM - STL

DSMSTL

Des Moines

Sun 6/15

6:32 pm-6:41 pm

2 stops24h 09m

Lambert-St Louis

Fri 6/27

9:50 am-6:11 pm

2 stops8h 21m

$378

Des MoinesSt. Louis

DSM - STL

DSMSTL

Des Moines

Fri 5/2

8:07 am-2:47 pm

1 stop6h 40m

Lambert-St Louis

Sun 5/4

5:29 pm-9:52 pm

1 stop4h 23m

$393

Flights are sorted by cheapest round-trip flights first.

Deals found on 4/16

Showing 1-10 of 24 results
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Best time to book a flight from Iowa to St. Louis

Have a flexible travel schedule? Discover the best time to fly to St. Louis from Iowa with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Iowa to St. Louis

What is the cheapest month to book a flight from Iowa to St. Louis?

Currently, August is the cheapest month in which you can book a flight from Iowa to St. Louis (average of $311). Flying from Iowa to St. Louis in March is currently the most expensive (average of $356). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from IA to STL?

Find hourly flight availability from Iowa to St. Louis. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated April 17, 2025.

When flying from Iowa to St. Louis, the time of day you decide to fly out makes little to no difference towards the overall price you’ll pay on tickets.

Rainfall in St. Louis by month

Plan your trip to St. Louis by taking into account the average rainfall totals by month.

In terms of precipitation, rainfall in St. Louis ranges from 2.2 - 4.7 inches per month. May is typically the wettest month, when rainfall can reach 4.7 in. February is typically the driest time to visit St. Louis when rainfall is around 2.2 in.

Temperature in St. Louis by month

Plan your trip to St. Louis by taking into account the average temperature totals by month.

If weather is an important factor for your trip to St. Louis, use this chart to help with planning. For those seeking warmer temperatures, July is the ideal time of year to visit, when temperatures reach an average of 80.6 F. Travelers looking to avoid the cold should look outside of January, when temperatures are typically at their lowest (around 32.0 F).

Reviews of airlines servicing St. Louis

Get insights into the airlines that provide service to St. Louis. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to St. Louis. Reviews last updated April 17, 2025.
To help decide which airline to fly from Iowa to St. Louis, see what other customers have to say about Alaska Airlines, Southwest and Delta. You can also see how each airline stacks up in terms of entertainment options, comfort, food, crew/service, and boarding process.
Alaska Airlines
8.0
Very good
9,887 reviews

Overall

8.0

Food

7.1

Boarding

8.1

Comfort

7.9

Entertainment

7.1

Crew

8.5

Reviews

1 / 20
4.0
Okay

Anonymous,Apr 2025

LAS - STS

flight was delayed both ways even tho the weather was clear >
Alaska Airlines
8.0
Very good
9,887 reviews
Alaska Airlines
8.0
Very good
9,887 reviews

Overall

8.0

Food

7.1

Boarding

8.1

Comfort

7.9

Entertainment

7.1

Crew

8.5

Reviews

1 / 20
4.0
Okay

Anonymous,Apr 2025

LAS - STS

flight was delayed both ways even tho the weather was clear >
Southwest
8.0
Very good
4,280 reviews
Alaska Airlines
8.0
Very good
9,887 reviews

Overall

8.0

Food

7.1

Boarding

8.1

Comfort

7.9

Entertainment

7.1

Crew

8.5

Reviews

1 / 20
4.0
Okay

Anonymous,Apr 2025

LAS - STS

flight was delayed both ways even tho the weather was clear >
Delta
8.0
Very good
7,916 reviews
Alaska Airlines
8.0
Very good
9,887 reviews

Overall

8.0

Food

7.1

Boarding

8.1

Comfort

7.9

Entertainment

7.1

Crew

8.5

Reviews

1 / 20
4.0
Okay

Anonymous,Apr 2025

LAS - STS

flight was delayed both ways even tho the weather was clear >
United Airlines
7.4
Good
8,667 reviews
Alaska Airlines
8.0
Very good
9,887 reviews

Overall

8.0

Food

7.1

Boarding

8.1

Comfort

7.9

Entertainment

7.1

Crew

8.5

Reviews

1 / 20
4.0
Okay

Anonymous,Apr 2025

LAS - STS

flight was delayed both ways even tho the weather was clear >
American Airlines
7.2
Good
10,000 reviews
Alaska Airlines
8.0
Very good
9,887 reviews

Overall

8.0

Food

7.1

Boarding

8.1

Comfort

7.9

Entertainment

7.1

Crew

8.5

Reviews

1 / 20
4.0
Okay

Anonymous,Apr 2025

LAS - STS

flight was delayed both ways even tho the weather was clear >

Related info for your journey

Find useful and relevant information for your journey from Iowa to St. Louis. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly into for flights to St. Louis from Iowa?

    Lambert-St Louis (STL) is the airport you will fly into if you book a flight from Iowa to St. Louis. It is only a 12.7 mi journey from Lambert-St Louis (STL) to St. Louis’s city center.

  • How popular is this Iowa to St. Louis flight route?

    Within the past month, 23 users have taken a look at flights from Iowa to Lambert-St Louis.

  • What are the cheapest airlines to fly from Iowa to St. Louis one-way?

    $49 is the cheapest one-way deal found within the past few days, from Southwest. You may also be able to find cheap deals on United Airlines and Delta, with prices starting from $80 and $89, respectively.

  • What are the most popular routes from Iowa to St. Louis?

    The most popular flight routes from Iowa to St. Louis are Omaha Eppley Airfield - Lambert-St Louis, Des Moines - Lambert-St Louis and La Crosse - Lambert-St Louis.

  • What are the cheapest flights from Iowa to St. Louis?

    On average you can expect to pay $306 for a flight from Iowa to St. Louis. The cheapest flight overall is $134 while the most popular route, (Omaha Eppley Airfield - Lambert-St Louis) is currently priced at $251.

  • Can I find deals for flights from Iowa to St. Louis that include hotel bookings?

    Yes. In addition to deals on Iowa to St. Louis flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Iowa to St. Louis?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Iowa to St. Louis.

  • Can I find deals for business class flights from Iowa to St. Louis?

    Yes. Cheapflights offers flight deals from Iowa to St. Louis by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Iowa to St. Louis?

    Currently, August is the cheapest month in which you can book a flight from Iowa to St. Louis (average of $311). Flying from Iowa to St. Louis in March is currently the most expensive (average of $356). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Traveling to a place near Iowa?

Book flights to Iowa if you plan to visit one of these locations
Fenton
Maryland Heights
Fairview Heights
Collinsville
Wentzville
Eureka
St. Peters
Festus
Glencoe
Alton
Farmington
Chesterfield

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Alternative routes for Iowa to St. Louis

See prices for flight routes from nearby airports that may be better suited for you.
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Top 4 airlines flying from Iowa to St. Louis

Discover the top 4 airlines that operate flights from Iowa to St. Louis. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated April 17, 2025.
AirlineCheapestAverageFlexibilityOn-time
SouthwestCheapest$117Average$310FlexibilityNo cancel feeOn-time63%
DeltaCheapest$155Average$470FlexibilityNo cancel feeOn-timeN/A
American AirlinesCheapest$217Average$298FlexibilityNo cancel feeOn-time71%
United AirlinesCheapest$217Average$328FlexibilityNo cancel feeOn-time69%

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