How popular is this Fort Myers to St. Louis flight route?

Flights from Fort Myers SW Florida Intl to Lambert-St Louis have been viewed 9 times in the past calendar month.

What are the cheapest airlines flying from Fort Myers to St. Louis round-trip?

Flying on Southwest is currently your cheapest option to St. Louis, with prices starting at $323. Additional round-trip tickets that might be worth considering are offered by Delta and American Airlines, with the lowest prices starting at $325 and $348, respectively. Users have found that Southwest is 24% cheaper than the other options available to this destination.

What are the cheapest airlines to fly from Fort Myers to St. Louis one-way?

The cheapest airline one-way is Spirit Airlines, with whom users have recently found tickets for as low as $117. However, be on the lookout for offers from Sun Country Air and American Airlines, as they are both options that can get you from Fort Myers to St. Louis for a low price.

What is the cheapest day to fly from Fort Myers to St. Louis?

Travelers seeking maximum savings on their Fort Myers to St. Louis flight should consider departing on Wednesday at noon when fares are most often at their lowest. Monday mornings flights should be avoided if possible as fares are typically the most expensive at this time.

What are the cheapest flights from Fort Myers to St. Louis?

While on average a flight from Fort Myers to St. Louis is generally $332, our data shows the cheapest flight currently is $114. When looking at the most popular route, (Fort Myers SW Florida Intl - Lambert-St Louis), you can expect to pay $287 for that flight.

What are the most popular airlines that fly from Fort Myers to St. Louis?

American Airlines, Delta and Southwest are the most popular airlines when flying from Fort Myers to St. Louis.

What is the cheapest day to fly round-trip from Fort Myers to St. Louis?

Travelers have found that booking a Wednesday departure is the best way to save up to 41% on the cost of booking your flights compared to booking on days of the week where this route is of high demand.

How far in advance should I book a flight from Fort Myers to St. Louis?

To save up to 411% on this flight, we recommend booking at least 37 days prior to travel. The price may fluctuate and will likely increase closer to your departure date. Users on Cheapflights have found tickets from Fort Myers to St. Louis from $418 1-2 weeks out and tickets from $634 for flights departing within the next 72 hours.

What is the cheapest month to fly from Fort Myers to St. Louis?

January can be a great time to fly to St. Louis from Fort Myers with a flight ticket averaging about $426. Cheapflights users have found deals in the month of January for as cheap as $246. The most expensive prices can be found in the month of February.

Most accurate provider : When it comes to deals on Fort Myers-St. Louis flights, users find the pricing of FlightHub to be most consistent on Cheapflights vs. FlightHub Users can find the same prices on Fort Myers-St. Louis flight deals on Cheapflights vs. FlightHub >95% of the time. Price accuracy is based on data collected from Fort Myers-St. Louis flight searches over the past month and is updated monthly.

Most trusted provider : When it comes to deals on Fort Myers-St. Louis flights, Cheapflights users trust eDreams the most. eDreams has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Fort Myers-St. Louis flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.

What airports do I use to fly from Fort Myers to St. Louis?

If you wish to fly to St. Louis from Fort Myers, then you need to book flights from Fort Myers SW Florida Intl to Lambert-St Louis. There are 2 flights from SW Florida Intl (RSW) to Lambert-St Louis (STL) per day to choose from. Flights to St. Louis from SW Florida Intl are available from 3 different airlines, which means you should have some options if you want to compare airfare deals. 2h 35m is how long a nonstop flight from Fort Myers to Lambert-St Louis typically takes.

Can I find deals for flights from Fort Myers to St. Louis that include hotel bookings?

Yes. In addition to deals on Fort Myers to St. Louis flights, Cheapflights offers vacation packages that include both flights and hotel.

How can I find direct flights from Fort Myers to St. Louis?

After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Fort Myers to St. Louis.

Can I find deals for business class flights from Fort Myers to St. Louis?

Yes. Cheapflights offers flight deals from Fort Myers to St. Louis by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

$117+ Flights from Fort Myers to St. Louis

Home Search by date Vacation packages Hotels Flight deals Car rental Travel tips & news

Find cheap flights from Fort Myers to St. Louis with Cheapflights

1. Tell us where you want to go

Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”

2. Select your favorite providers

We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.

3. Compare prices and book

Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.

Cheapflights Tip: The best prices from Fort Myers SW Florida Intl to Lambert-St Louis are usually found in January or August, booked 36 days in advance, depart on a Thursday or Wednesday and return on a Friday

Cheap flight deals from Fort Myers to St. Louis

Most accurate provider	FlightHub 3 stars
Most trusted provider	eDreams 3 stars
Round-trip from	$290 (Mytrip)
One-way from	$117 (Mytrip)
Popular in	February
Cheapest in	January
Average price	$418

Provider with most accurate pricing for Fort Myers SW Florida Intl-Lambert-St Louis flight deals.

Search Deals

Provider most trusted by Cheapflights users for Fort Myers SW Florida Intl-Lambert-St Louis flights.

Search Deals

From Fort Myers SW Florida Intl to Lambert-St Louis

Search Deals

One-way flight from Fort Myers SW Florida Intl to Lambert-St Louis

Search Deals

Highest demand for flights based on searches. 6% potential increase in price ($29 potential increase over avg. RT price).

Search Deals

Cheapest flight prices on average. 3% potential price decrease ($15 potential savings vs. average RT price).

Search Deals

Average for round-trip flights in April 2025

Search Deals

Find flight deals from Fort Myers to St. Louis

Cheapest flights from Fort Myers to St. Louis
Explore the most affordable flight options available from Fort Myers to St. Louis. Find the lowest fares from popular airlines and budget airlines, with prices last updated on April 22, 2025.

Thu 5/227:36 pmRSW - STL

1 stop16h 49mMultiple Airlines

Thu 5/2912:15 pmSTL - RSW

2 stops26h 58mMultiple Airlines

Deal found 4/22

$290

Thu 5/227:30 amRSW - STL

Nonstop2h 40mSouthwest

Thu 5/292:55 pmSTL - RSW

Nonstop2h 25mSouthwest

Deal found 4/22

$323

Thu 5/297:40 amRSW - STL

1 stop8h 20mDelta

Tue 6/105:23 pmSTL - RSW

1 stop4h 11mDelta

Deal found 4/22

$325

Tue 6/172:34 pmRSW - STL

1 stop6h 45mAmerican Airlines

Wed 6/257:20 amSTL - RSW

2 stops7h 00mAmerican Airlines

Deal found 4/22

$348

Thu 5/17:30 pmRSW - STL

1 stop17h 01mSun Country Air

Sun 5/48:00 amSTL - RSW

1 stop25h 23mSun Country Air

Deal found 4/22

$405

Thu 5/84:57 pmRSW - STL

1 stop6h 06mUnited Airlines

Mon 5/1210:39 amSTL - RSW

2 stops10h 21mUnited Airlines

Deal found 4/22

$422

Thu 5/293:59 pmRSW - STL

2 stops23h 08mAlaska Airlines

Tue 6/103:03 pmSTL - RSW

2 stops19h 46mAlaska Airlines

Deal found 4/22

$1,309

Best flights from Fort Myers to St. Louis
Discover carefully curated flight deals from Fort Myers to St. Louis that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated April 22, 2025.

Thu 5/227:36 pmRSW - STL

1 stop16h 49mMultiple Airlines

Thu 5/2912:15 pmSTL - RSW

2 stops26h 58mMultiple Airlines

Deal found 4/22

$290

Thu 5/227:30 amRSW - STL

Nonstop2h 40mSouthwest

Thu 5/292:55 pmSTL - RSW

Nonstop2h 25mSouthwest

Deal found 4/22

$323

Thu 5/297:40 amRSW - STL

1 stop8h 20mDelta

Tue 6/105:23 pmSTL - RSW

1 stop4h 11mDelta

Deal found 4/22

$325

Tue 6/172:34 pmRSW - STL

1 stop6h 45mAmerican Airlines

Wed 6/257:20 amSTL - RSW

2 stops7h 00mAmerican Airlines

Deal found 4/22

$348

Thu 5/17:30 pmRSW - STL

1 stop17h 01mSun Country Air

Sun 5/48:00 amSTL - RSW

1 stop25h 23mSun Country Air

Deal found 4/22

$405

Thu 5/84:57 pmRSW - STL

1 stop6h 06mUnited Airlines

Mon 5/1210:39 amSTL - RSW

2 stops10h 21mUnited Airlines

Deal found 4/22

$422

Thu 5/293:59 pmRSW - STL

2 stops23h 08mAlaska Airlines

Tue 6/103:03 pmSTL - RSW

2 stops19h 46mAlaska Airlines

Deal found 4/22

$1,309

Last-minute flights from Fort Myers to St. Louis
Discover last-minute flight deals from Fort Myers to St. Louis. Data last updated April 22, 2025 and is based on user searches.

Sun 4/273:01 pmRSW - STL

3 stops28h 40mMultiple Airlines

Sun 5/48:00 amSTL - RSW

1 stop12h 24mMultiple Airlines

Deal found 4/22

$382

Tue 4/294:33 pmRSW - STL

1 stop8h 01mDelta

Tue 5/66:50 amSTL - RSW

1 stop7h 23mDelta

Deal found 4/22

$377

Tue 4/296:00 amRSW - STL

2 stops9h 42mUnited Airlines

Tue 5/68:22 amSTL - RSW

1 stop6h 48mUnited Airlines

Deal found 4/22

$452

Thu 5/17:30 pmRSW - STL

1 stop17h 01mSun Country Air

Sun 5/48:00 amSTL - RSW

1 stop25h 23mSun Country Air

Deal found 4/22

$405

Fri 5/23:10 pmRSW - STL

1 stop6h 37mAmerican Airlines

Sun 5/49:18 amSTL - RSW

1 stop6h 17mAmerican Airlines

Deal found 4/22

$417

Fri 5/25:00 amRSW - STL

1 stop6h 45mSouthwest

Sun 5/44:00 pmSTL - RSW

Nonstop2h 30mSouthwest

Deal found 4/22

$552

Thu 5/84:57 pmRSW - STL

1 stop6h 06mUnited Airlines

Mon 5/1210:39 amSTL - RSW

2 stops10h 21mUnited Airlines

Deal found 4/22

$422

Thu 5/227:36 pmRSW - STL

1 stop16h 49mMultiple Airlines

Thu 5/2912:15 pmSTL - RSW

2 stops26h 58mMultiple Airlines

Deal found 4/22

$290

Thu 5/227:30 amRSW - STL

Nonstop2h 40mSouthwest

Thu 5/292:55 pmSTL - RSW

Nonstop2h 25mSouthwest

Deal found 4/22

$323

Thu 5/297:40 amRSW - STL

1 stop8h 20mDelta

Tue 6/105:23 pmSTL - RSW

1 stop4h 11mDelta

Deal found 4/22

$325

Thu 5/293:59 pmRSW - STL

2 stops23h 08mAlaska Airlines

Tue 6/103:03 pmSTL - RSW

2 stops19h 46mAlaska Airlines

Deal found 4/22

$1,309

One-way flights from Fort Myers to St. Louis
Search for one-way flight options from Fort Myers to St. Louis. Find affordable one-way fares based on user searches. Data last updated April 22, 2025.

Wed 6/188:09 pmRSW - STL

1 stop21h 55mSpirit Airlines

Deal found 4/22

$117

Thu 5/229:30 amRSW - STL

1 stop26h 55mSun Country Air

Deal found 4/21

$128

Tue 7/112:47 pmRSW - STL

1 stop8h 43mAmerican Airlines

Deal found 4/22

$135

Sat 5/246:05 amRSW - STL

Nonstop2h 40mSouthwest

Deal found 4/22

$144

Tue 5/208:19 amRSW - STL

1 stop7h 16mDelta

Deal found 4/21

$154

Sat 5/242:00 pmRSW - STL

2 stops9h 45mUnited Airlines

Deal found 4/22

$159

Thu 5/299:15 amRSW - STL

2 stops35h 55mMultiple Airlines

Deal found 4/22

$165

Cheapflights Fare Finder

Use the filters below to find and compare flights from Fort Myers to St. Louis that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Fort MyersSt. Louis

RSW - STL

RSWSTL

Fort Myers SW Florida Intl

Thu 5/22

7:36 pm-11:25 am

1 stop16h 49m

Lambert-St Louis

Thu 5/29

12:15 pm-4:13 pm

2 stops26h 58m

$290

Fort MyersSt. Louis

RSW - STL

RSWSTL

Fort Myers SW Florida Intl

Thu 5/22

7:30 am-9:10 am

Nonstop2h 40m

Lambert-St Louis

Thu 5/29

2:55 pm-6:20 pm

Nonstop2h 25m

$323

Fort MyersSt. Louis

RSW - STL

RSWSTL

Fort Myers SW Florida Intl

Thu 5/29

7:40 am-3:00 pm

1 stop8h 20m

Lambert-St Louis

Tue 6/10

5:23 pm-10:34 pm

1 stop4h 11m

$325

Fort MyersSt. Louis

RSW - STL

RSWSTL

Fort Myers SW Florida Intl

Tue 6/17

2:34 pm-8:19 pm

1 stop6h 45m

Lambert-St Louis

Wed 6/25

7:20 am-3:20 pm

2 stops7h 00m

$348

Fort MyersSt. Louis

RSW - STL

RSWSTL

Fort Myers SW Florida Intl

Thu 5/1

7:30 pm-11:31 am

1 stop17h 01m

Lambert-St Louis

Sun 5/4

8:00 am-10:23 am

1 stop25h 23m

$405

Fort MyersSt. Louis

RSW - STL

RSWSTL

Fort Myers SW Florida Intl

Thu 5/8

4:57 pm-10:03 pm

1 stop6h 06m

Lambert-St Louis

Mon 5/12

10:39 am-10:00 pm

2 stops10h 21m

$422

Fort MyersSt. Louis

RSW - STL

RSWSTL

Fort Myers SW Florida Intl

Thu 5/29

3:59 pm-2:07 pm

2 stops23h 08m

Lambert-St Louis

Tue 6/10

3:03 pm-11:49 am

2 stops19h 46m

$1,309

Fort MyersSt. Louis

RSW - STL

RSWSTL

Fort Myers SW Florida Intl

Wed 6/18

8:09 pm-5:04 pm

1 stop21h 55m

$117

Fort MyersSt. Louis

RSW - STL

RSWSTL

Fort Myers SW Florida Intl

Thu 5/22

9:30 am-11:25 am

1 stop26h 55m

$128

Fort MyersSt. Louis

RSW - STL

RSWSTL

Fort Myers SW Florida Intl

Tue 7/1

12:47 pm-8:30 pm

1 stop8h 43m

$135

Flights are sorted by cheapest round-trip flights first.

Deals found on 4/22

Showing 1-10 of 14 results

Compare providers for flights from Fort Myers to St. Louis

Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Fort Myers to St. Louis in April.

Provider	Price Accuracy	Trust Score*
Expedia	Price Accuracy1 star	Trust Score*3 stars
FlightHub	Price Accuracy3 stars	Trust Score*2 stars
eDreams	Price Accuracy3 stars	Trust Score*3 stars
Priceline	Price Accuracy1 star	Trust Score*3 stars

*The Trust Score is based on feedback from users after their booking experience. It measures overall satisfaction, helping us identify issues like hidden fees, problems during the ticketing process, and the quality of customer service. This score is our best indicator of the provider's quality and reliability.

Most accurate provider: When it comes to deals on Fort Myers-St. Louis flights, users find the pricing of FlightHub to be most consistent on Cheapflights vs. FlightHub Users can find the same prices on Fort Myers-St. Louis flight deals on Cheapflights vs. FlightHub >95% of the time. Price accuracy is based on data collected from Fort Myers-St. Louis flight searches over the past month and is updated monthly.
Most trusted provider: When it comes to deals on Fort Myers-St. Louis flights, Cheapflights users trust eDreams the most. eDreams has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Fort Myers-St. Louis flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.

Best time to book a flight from Fort Myers to St. Louis

Have a flexible travel schedule? Discover the best time to fly to St. Louis from Fort Myers with our price prediction graph.

Estimated round-trip price

Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Fort Myers to St. Louis

How far ahead should I book a flight from Fort Myers to St. Louis?

The best time to book flights from Fort Myers to St. Louis is 36 days before your desired departure date. The cost of your flight will likely increase significantly if you book two weeks in advance of your flight.

What is the cheapest month to book a flight from Fort Myers to St. Louis?

Currently, August is the cheapest month in which you can book a flight from Fort Myers to St. Louis (average of $311). Flying from Fort Myers to St. Louis in March is currently the most expensive (average of $356). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from RSW to STL?

One of the essential ways to save on airfare from Fort Myers to St. Louis is to remain as flexible as possible. Flights that are in the evening tend to be the most expensive. A flight in the afternoon could potentially save you up to 8% on airfare.

Rainfall in St. Louis by month

In terms of precipitation, rainfall in St. Louis ranges from 2.2 - 4.7 inches per month. May is typically the wettest month, when rainfall can reach 4.7 in. February is typically the driest time to visit St. Louis when rainfall is around 2.2 in.

Temperature in St. Louis by month

If weather is an important factor for your trip to St. Louis, use this chart to help with planning. For those seeking warmer temperatures, July is the ideal time of year to visit, when temperatures reach an average of 80.6 F. Travelers looking to avoid the cold should look outside of January, when temperatures are typically at their lowest (around 32.0 F).

Reviews of airlines servicing St. Louis

Get a feel of what it's like to fly with Alaska Airlines, Southwest and Delta from Fort Myers to St. Louis by reading reviews from past customers. In addition to providing an overall rating, users have also rated airlines in terms of entertainment options, comfort, food, crew/service, and boarding process.

Alaska Airlines

8.0

Very good

9,906 reviews

Reviews

1 / 20

4.0

Okay

Anonymous,Apr 2025

LAS - STS

flight was delayed both ways even tho the weather was clear >

Alaska Airlines

8.0

Very good

9,906 reviews

Alaska Airlines

8.0

Very good

9,906 reviews

Reviews

1 / 20

4.0

Okay

Anonymous,Apr 2025

LAS - STS

flight was delayed both ways even tho the weather was clear >

Southwest

8.0

Very good

4,286 reviews

Alaska Airlines

8.0

Very good

9,906 reviews

Reviews

1 / 20

4.0

Okay

Anonymous,Apr 2025

LAS - STS

flight was delayed both ways even tho the weather was clear >

Delta

8.0

Very good

7,920 reviews

Alaska Airlines

8.0

Very good

9,906 reviews

Reviews

1 / 20

4.0

Okay

Anonymous,Apr 2025

LAS - STS

flight was delayed both ways even tho the weather was clear >

United Airlines

7.4

Good

8,683 reviews

Alaska Airlines

8.0

Very good

9,906 reviews

Reviews

1 / 20

4.0

Okay

Anonymous,Apr 2025

LAS - STS

flight was delayed both ways even tho the weather was clear >

American Airlines

7.2

Good

10,000 reviews

Alaska Airlines

8.0

Very good

9,906 reviews

Reviews

1 / 20

4.0

Okay

Anonymous,Apr 2025

LAS - STS

flight was delayed both ways even tho the weather was clear >

Related info for your journey

What airports do I use to fly from Fort Myers to St. Louis?
If you wish to fly to St. Louis from Fort Myers, then you need to book flights from Fort Myers SW Florida Intl to Lambert-St Louis. There are 2 flights from SW Florida Intl (RSW) to Lambert-St Louis (STL) per day to choose from. Flights to St. Louis from SW Florida Intl are available from 3 different airlines, which means you should have some options if you want to compare airfare deals. 2h 35m is how long a nonstop flight from Fort Myers to Lambert-St Louis typically takes.
How popular is this Fort Myers to St. Louis flight route?
Flights from Fort Myers SW Florida Intl to Lambert-St Louis have been viewed 9 times in the past calendar month.
What are the cheapest airlines flying from Fort Myers to St. Louis round-trip?
Flying on Southwest is currently your cheapest option to St. Louis, with prices starting at $323. Additional round-trip tickets that might be worth considering are offered by Delta and American Airlines, with the lowest prices starting at $325 and $348, respectively. Users have found that Southwest is 24% cheaper than the other options available to this destination.
What are the cheapest airlines to fly from Fort Myers to St. Louis one-way?
The cheapest airline one-way is Spirit Airlines, with whom users have recently found tickets for as low as $117. However, be on the lookout for offers from Sun Country Air and American Airlines, as they are both options that can get you from Fort Myers to St. Louis for a low price.
What are the cheapest flights from Fort Myers to St. Louis?
While on average a flight from Fort Myers to St. Louis is generally $332, our data shows the cheapest flight currently is $114. When looking at the most popular route, (Fort Myers SW Florida Intl - Lambert-St Louis), you can expect to pay $287 for that flight.
Can I find deals for flights from Fort Myers to St. Louis that include hotel bookings?
Yes. In addition to deals on Fort Myers to St. Louis flights, Cheapflights offers vacation packages that include both flights and hotel.
How can I find direct flights from Fort Myers to St. Louis?
After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Fort Myers to St. Louis.
Can I find deals for business class flights from Fort Myers to St. Louis?
Yes. Cheapflights offers flight deals from Fort Myers to St. Louis by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.
What is the cheapest month to book a flight from Fort Myers to St. Louis?
Currently, August is the cheapest month in which you can book a flight from Fort Myers to St. Louis (average of $311). Flying from Fort Myers to St. Louis in March is currently the most expensive (average of $356). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Fenton

Maryland Heights

Fairview Heights

Collinsville

Wentzville

Eureka

St. Peters

Festus

Glencoe

Alton

Farmington

Browse thousands of different options on Cheapflights for your next trip

Alternative routes for Fort Myers to St. Louis

Orlando to St. Louis flights

Orlando to Kansas City flights

Miami to St. Louis flights

Tampa to Kansas City flights

Tampa to St. Louis flights

Miami to Kansas City flights

Fort Lauderdale to Kansas City flights

Jacksonville to St. Louis flights

Sarasota to Kansas City flights

Fort Lauderdale to St. Louis flights

West Palm Beach to St. Louis flights

Jacksonville to Kansas City flights

Sarasota to St. Louis flights

Fort Myers to Kansas City flights

Orlando to Springfield flights

Miami to Springfield flights

Tampa to Springfield flights

West Palm Beach to Kansas City flights

Melbourne to St. Louis flights

Daytona Beach to Kansas City flights

Pensacola to Kansas City flights

Gainesville to St. Louis flights

West Palm Beach to Springfield flights

Panama City to Kansas City flights

Sarasota to Springfield flights

Jacksonville to Springfield flights

Fort Lauderdale to Springfield flights

Pensacola to St. Louis flights

Pensacola to Springfield flights

Panama City to St. Louis flights

Valparaiso to St. Louis flights

Fort Myers to Springfield flights

Tallahassee to Kansas City flights

Tallahassee to St. Louis flights

Sarasota to Joplin flights

Daytona Beach to St. Louis flights

Orlando to Joplin flights

Melbourne to Kansas City flights

Valparaiso to Kansas City flights

Daytona Beach to Springfield flights

Panama City to Springfield flights

Gainesville to Kansas City flights

Jacksonville to Joplin flights

Fort Myers to Joplin flights

Melbourne to Springfield flights

Orlando to Columbia flights

Valparaiso to Columbia flights

Tampa to Columbia flights

West Palm Beach to Columbia flights

Complete your trip

St. Louis car rentals

Lambert-St Louis Airport car rentals

Springfield Capital Airport car rentals

Belleville Airport car rentals

Marion Williamson County Airport car rentals

Kansas City car rentals

Springfield car rentals

Columbia car rentals

Joplin car rentals

Fort Leonard Wood car rentals

Downtown car rentals

The Hill car rentals

Other flights to St. Louis

Top 3 airlines flying from Fort Myers to St. Louis

Airline	Cheapest	Average	Flexibility	On-time
American Airlines	Cheapest$245	Average$368	FlexibilityNo cancel fee	On-time71%
Delta	Cheapest$248	Average$427	FlexibilityNo cancel fee	On-timeN/A
Southwest	Cheapest$268	Average$404	FlexibilityNo cancel fee	On-time63%

100% Free

Cheapflights is completely free to use, so you can start saving the moment you arrive.

Book with Flexibility

Our users can plan ahead with confidence and find flights with no change fees

Travel Smart

Millions of people come to us for their flight needs every year. We help make travel planning easy by providing useful insights and data-driven graphs that can inform your decisions.

$117+ Cheap flights from Fort Myers to St. Louis (RSW - STL)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 6/18. Fares are subject to change and may not be available on all flights or dates of travel.

Find cheap flights from Fort Myers to St. Louis with Cheapflights

1. Tell us where you want to go

2. Select your favorite providers

3. Compare prices and book

Cheapflights Tip: The best prices from Fort Myers SW Florida Intl to Lambert-St Louis are usually found in January or August, booked 36 days in advance, depart on a Thursday or Wednesday and return on a Friday

Cheap flight deals from Fort Myers to St. Louis

Most accurate provider

Most trusted provider

Round-trip from

One-way from

Popular in

Cheapest in

Average price

Find flight deals from Fort Myers to St. Louis

Cheapest flights from Fort Myers to St. LouisExplore the most affordable flight options available from Fort Myers to St. Louis. Find the lowest fares from popular airlines and budget airlines, with prices last updated on April 22, 2025.

Explore the most affordable flight options available from Fort Myers to St. Louis. Find the lowest fares from popular airlines and budget airlines, with prices last updated on April 22, 2025.

Cheapflights Fare Finder

Use the filters below to find and compare flights from Fort Myers to St. Louis that are best for you.

Compare providers for flights from Fort Myers to St. Louis

Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.

Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Fort Myers to St. Louis in April.

Best time to book a flight from Fort Myers to St. Louis

Have a flexible travel schedule? Discover the best time to fly to St. Louis from Fort Myers with our price prediction graph.

Cheapflights Insights

Everything you need to know about your flight from Fort Myers to St. Louis

How far ahead should I book a flight from Fort Myers to St. Louis?

Use this chart to determine the optimal time to book a round-trip flight from Fort Myers to St. Louis. Price data was last updated on April 18, 2025.

What is the cheapest month to book a flight from Fort Myers to St. Louis?

What is the cheapest time of day to fly from RSW to STL?

Find hourly flight availability from Fort Myers to St. Louis. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated April 22, 2025.

Rainfall in St. Louis by month

Plan your trip to St. Louis by taking into account the average rainfall totals by month.

Temperature in St. Louis by month

Plan your trip to St. Louis by taking into account the average temperature totals by month.

Reviews of airlines servicing St. Louis

Related info for your journey

Find useful and relevant information for your journey from Fort Myers to St. Louis. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

What airports do I use to fly from Fort Myers to St. Louis?

How popular is this Fort Myers to St. Louis flight route?

What are the cheapest airlines flying from Fort Myers to St. Louis round-trip?

What are the cheapest airlines to fly from Fort Myers to St. Louis one-way?

What are the cheapest flights from Fort Myers to St. Louis?

Can I find deals for flights from Fort Myers to St. Louis that include hotel bookings?

How can I find direct flights from Fort Myers to St. Louis?

Can I find deals for business class flights from Fort Myers to St. Louis?

What is the cheapest month to book a flight from Fort Myers to St. Louis?

Traveling to a place near Fort Myers?

Browse thousands of different options on Cheapflights for your next trip

Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.

Alternative routes for Fort Myers to St. Louis

See prices for flight routes from nearby airports that may be better suited for you.

Top 3 airlines flying from Fort Myers to St. Louis

100% Free

Book with Flexibility

Travel Smart

Cheapest flights from Fort Myers to St. Louis
Explore the most affordable flight options available from Fort Myers to St. Louis. Find the lowest fares from popular airlines and budget airlines, with prices last updated on April 22, 2025.