What are the cheapest airlines flying from Detroit to St. Louis round-trip?

Our cheapest airline available from Detroit to St. Louis is American Airlines. Our recent data shows that you can find tickets from as low as $219 on this airline. Additional options worth looking into are Delta and Southwest, starting at $231 and $233 round-trip. You may be able to fly from Detroit to St. Louis for 33% less than the average price by searching for these airlines.

What are the cheapest airlines to fly from Detroit to St. Louis one-way?

$68 is the cheapest one-way deal found within the past few days, from Spirit Airlines. You may also be able to find cheap deals on Frontier and American Airlines, with prices starting from $86 and $91, respectively.

What is the cheapest day to fly from Detroit to St. Louis?

Travelers seeking maximum savings on their Detroit to St. Louis flight should consider departing on Tuesday at noon when fares are most often at their lowest. Sunday at noon flights should be avoided if possible as fares are typically the most expensive at this time.

What are the cheapest flights from Detroit to St. Louis?

While on average a flight from Detroit to St. Louis is generally $291, our data shows the cheapest flight currently is $62. When looking at the most popular route, (Detroit Metropolitan Wayne County - Lambert-St Louis), you can expect to pay $138 for that flight.

What are the most reliable airlines from Detroit to St. Louis?

Looking for the most reliable airlines to get you to your destination on time? Our data shows these are most likely to get you from Detroit to St. Louis on time: Aeromexico (91%), SkyWest Airlines (90%), Southwest (89%).

What are the most popular airlines that fly from Detroit to St. Louis?

When booking a flight from Detroit to St. Louis, you may want to consider flying on American Airlines, Delta or Frontier as they are the most popular for this route.

What is the cheapest day to fly round-trip from Detroit to St. Louis?

Departing on a Wednesday is a good option for securing a great price. You can expect to save up to 30% when planning your travel around this day of the week.

How far in advance should I book a flight from Detroit to St. Louis?

Users have found that booking a flight from Detroit to St. Louis at least 38 days early can save you up to 69% on average compared to booking a flight this week. If booking 38 days before your flight isn’t an option for you, users have found flights from Detroit to St. Louis for as little as $286 when booking for a departure date within the next two weeks. You can also check prices now. Some users have found airline tickets as low as $582 for flights departing within the next 3 days.

What is the cheapest month to fly from Detroit to St. Louis?

Flights from Detroit to St. Louis lean towards being more expensive in September. Prices are generally better when you fly from Detroit to St. Louis in March, with the cheapest ticket starting at $245.

Most accurate provider : When it comes to deals on Detroit-St. Louis flights, users find the pricing of FlightHub to be most consistent on Cheapflights vs. FlightHub Users can find the same prices on Detroit-St. Louis flight deals on Cheapflights vs. FlightHub >95% of the time. Price accuracy is based on data collected from Detroit-St. Louis flight searches over the past month and is updated monthly.

Most trusted provider : When it comes to deals on Detroit-St. Louis flights, Cheapflights users trust eDreams the most. eDreams has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Detroit-St. Louis flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.

What airports do I use to fly from Detroit to St. Louis?

You will need to book a flight from Detroit All airports to Lambert-St Louis if you want to fly from Detroit to St. Louis. At least 5 different airlines have flights from All airports (DTT) to Lambert-St Louis (STL) on a regular basis. There are 13 flights to St. Louis from the Detroit airport per day. If you manage to book one that is nonstop, then you can expect the flight time from DTT to STL to be around 1h 30m.

Can I find deals for flights from Detroit to St. Louis that include hotel bookings?

Yes. In addition to deals on Detroit to St. Louis flights, Cheapflights offers vacation packages that include both flights and hotel.

How can I find direct flights from Detroit to St. Louis?

After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Detroit to St. Louis.

Can I find deals for business class flights from Detroit to St. Louis?

Yes. Cheapflights offers flight deals from Detroit to St. Louis by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

$68+ Flights from Detroit to St. Louis

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Find cheap flights from Detroit to St. Louis with Cheapflights

1. Tell us where you want to go

Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”

2. Select your favorite providers

We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.

3. Compare prices and book

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Cheapflights Tip: The best prices from Detroit All airports to Lambert-St Louis are usually found in March or June, booked 79 days in advance, depart on a Thursday or Friday and return on a Friday

Cheap flight deals from Detroit to St. Louis

Most accurate provider	FlightHub 3 stars
Most trusted provider	eDreams 3 stars
Round-trip from	$219 (American Airlines)
One-way from	$68 (FlightHub)
Popular in	September
Cheapest in	March
Average price	$320
Good round-trip deal	$271 or less
Good one-way deal	$179 or less

Provider with most accurate pricing for Detroit (DTT)-Lambert-St Louis flight deals.

Search Deals

Provider most trusted by Cheapflights users for Detroit (DTT)-Lambert-St Louis flights.

Search Deals

From Detroit (DTT) to Lambert-St Louis

Search Deals

One-way flight from Detroit (DTT) to Lambert-St Louis

Search Deals

Highest demand for flights based on searches. 7% potential increase in price ($26 potential increase over avg. RT price).

Search Deals

Cheapest flight prices on average. 1% potential price decrease ($6 potential savings vs. average RT price).

Search Deals

Average for round-trip flights in April 2025

Search Deals

Price to beat on a round-trip flight from Detroit (DTT) to Lambert-St Louis.

Search Deals

Price to beat on a one-way flight from Detroit (DTT) to Lambert-St Louis.

Search Deals

Find flight deals from Detroit to St. Louis

Cheapest flights from Detroit to St. Louis
Explore the most affordable flight options available from Detroit to St. Louis. Find the lowest fares from popular airlines and budget airlines, with prices last updated on April 22, 2025.

Wed 5/2811:49 amDTW - STL

1 stop8h 40mAmerican Airlines

Fri 5/305:00 amSTL - DTW

1 stop3h 52mAmerican Airlines

Deal found 4/22

$219

Mon 5/198:11 pmDTW - STL

Nonstop1h 38mDelta

Wed 5/216:45 amSTL - DTW

Nonstop1h 32mDelta

Deal found 4/21

$231

Tue 6/101:35 pmDTW - STL

1 stop7h 20mSouthwest

Sat 6/143:25 pmSTL - DTW

2 stops6h 10mSouthwest

Deal found 4/21

$233

Fri 5/29:58 pmDTW - STL

1 stop27h 08mFrontier

Sun 5/45:45 pmSTL - DTW

1 stop23h 15mFrontier

Deal found 4/20

$237

Sun 5/1810:31 amDTW - STL

2 stops9h 10mMultiple Airlines

Sun 5/2510:20 amSTL - DTW

1 stop5h 50mMultiple Airlines

Deal found 4/20

$251

Fri 9/56:00 amDTW - STL

1 stop5h 40mUnited Airlines

Sun 9/75:30 pmSTL - DTW

1 stop3h 52mUnited Airlines

Deal found 4/21

$264

Fri 5/96:38 amDTW - STL

2 stops27h 37mSpirit Airlines

Sun 5/1110:10 amSTL - DTW

2 stops36h 10mSpirit Airlines

Deal found 4/21

$358

Best flights from Detroit to St. Louis
Discover carefully curated flight deals from Detroit to St. Louis that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated April 22, 2025.

Wed 5/2811:49 amDTW - STL

1 stop8h 40mAmerican Airlines

Fri 5/305:00 amSTL - DTW

1 stop3h 52mAmerican Airlines

Deal found 4/22

$219

Mon 5/198:11 pmDTW - STL

Nonstop1h 38mDelta

Wed 5/216:45 amSTL - DTW

Nonstop1h 32mDelta

Deal found 4/21

$231

Tue 6/101:35 pmDTW - STL

1 stop7h 20mSouthwest

Sat 6/143:25 pmSTL - DTW

2 stops6h 10mSouthwest

Deal found 4/21

$233

Fri 5/29:58 pmDTW - STL

1 stop27h 08mFrontier

Sun 5/45:45 pmSTL - DTW

1 stop23h 15mFrontier

Deal found 4/20

$237

Sun 5/1810:31 amDTW - STL

2 stops9h 10mMultiple Airlines

Sun 5/2510:20 amSTL - DTW

1 stop5h 50mMultiple Airlines

Deal found 4/20

$251

Tue 5/132:23 pmDTW - STL

2 stops8h 25mUnited Airlines

Fri 5/165:29 pmSTL - DTW

1 stop3h 38mUnited Airlines

Deal found 4/21

$329

Fri 5/96:38 amDTW - STL

2 stops27h 37mSpirit Airlines

Sun 5/1110:10 amSTL - DTW

2 stops36h 10mSpirit Airlines

Deal found 4/21

$358

Last-minute flights from Detroit to St. Louis
Discover last-minute flight deals from Detroit to St. Louis. Data last updated April 22, 2025 and is based on user searches.

Sun 4/275:00 amDTW - STL

1 stop13h 15mSpirit Airlines

Thu 5/16:10 pmSTL - DTW

2 stops18h 10mSpirit Airlines

Deal found 4/21

$582

Sun 4/275:40 amDTW - STL

2 stops7h 40mUnited Airlines

Mon 4/283:40 pmSTL - DTW

1 stop3h 42mUnited Airlines

Deal found 4/21

$636

Thu 5/110:35 pmDTW - STL

1 stop13h 56mMultiple Airlines

Mon 5/59:50 amSTL - DTW

2 stops14h 27mMultiple Airlines

Deal found 4/20

$316

Thu 5/18:55 pmDTW - STL

Nonstop1h 41mDelta

Mon 5/51:46 pmSTL - DTW

Nonstop1h 30mDelta

Deal found 4/20

$462

Thu 5/112:40 pmDTW - STL

Nonstop1h 35mSouthwest

Mon 5/57:45 amSTL - DTW

2 stops8h 25mSouthwest

Deal found 4/20

$477

Fri 5/29:58 pmDTW - STL

1 stop27h 08mFrontier

Sun 5/45:45 pmSTL - DTW

1 stop23h 15mFrontier

Deal found 4/20

$237

Mon 5/59:58 pmDTW - STL

1 stop27h 08mFrontier

Thu 5/85:45 pmSTL - DTW

1 stop23h 15mFrontier

Deal found 4/22

$232

Mon 5/58:20 amDTW - STL

2 stops16h 39mAlaska Airlines

Mon 5/126:52 amSTL - DTW

2 stops21h 19mAlaska Airlines

Deal found 4/21

$1,008

Fri 5/96:38 amDTW - STL

2 stops27h 37mSpirit Airlines

Sun 5/1110:10 amSTL - DTW

2 stops36h 10mSpirit Airlines

Deal found 4/21

$358

Tue 5/132:23 pmDTW - STL

2 stops8h 25mUnited Airlines

Fri 5/165:29 pmSTL - DTW

1 stop3h 38mUnited Airlines

Deal found 4/21

$329

Sun 5/1810:31 amDTW - STL

2 stops9h 10mMultiple Airlines

Sun 5/2510:20 amSTL - DTW

1 stop5h 50mMultiple Airlines

Deal found 4/20

$251

Mon 5/198:11 pmDTW - STL

Nonstop1h 38mDelta

Wed 5/216:45 amSTL - DTW

Nonstop1h 32mDelta

Deal found 4/21

$231

One-way flights from Detroit to St. Louis
Search for one-way flight options from Detroit to St. Louis. Find affordable one-way fares based on user searches. Data last updated April 22, 2025.

Thu 6/124:33 pmDTW - STL

Nonstop1h 31mSpirit Airlines

Deal found 4/21

$68

Sun 5/1812:54 pmDTW - STL

1 stop12h 12mFrontier

Deal found 4/21

$86

Mon 5/261:26 pmDTW - STL

1 stop9h 26mAmerican Airlines

Deal found 4/22

$91

Sat 6/147:50 pmDTW - STL

Nonstop1h 40mDelta

Deal found 4/21

$100

Tue 7/85:40 amDTW - STL

2 stops7h 30mSouthwest

Deal found 4/21

$115

Sat 5/242:30 pmDTW - STL

2 stops9h 15mUnited Airlines

Deal found 4/22

$124

Mon 5/2610:31 amDTW - STL

2 stops9h 10mMultiple Airlines

Deal found 4/22

$128

Cheapflights Fare Finder

Use the filters below to find and compare flights from Detroit to St. Louis that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

DetroitSt. Louis

DTW - STL

DTWSTL

Detroit Metropolitan Wayne County

Wed 5/28

11:49 am-7:29 pm

1 stop8h 40m

Lambert-St Louis

Fri 5/30

5:00 am-9:52 am

1 stop3h 52m

$219

DetroitSt. Louis

DTW - STL

DTWSTL

Detroit Metropolitan Wayne County

Mon 5/19

8:11 pm-8:49 pm

Nonstop1h 38m

Lambert-St Louis

Wed 5/21

6:45 am-9:17 am

Nonstop1h 32m

$231

DetroitSt. Louis

DTW - STL

DTWSTL

Detroit Metropolitan Wayne County

Tue 6/10

1:35 pm-7:55 pm

1 stop7h 20m

Lambert-St Louis

Sat 6/14

3:25 pm-10:35 pm

2 stops6h 10m

$233

DetroitSt. Louis

DTW - STL

DTWSTL

Detroit Metropolitan Wayne County

Fri 5/2

9:58 pm-12:06 am

1 stop27h 08m

Lambert-St Louis

Sun 5/4

5:45 pm-6:00 pm

1 stop23h 15m

$237

DetroitSt. Louis

DTW - STL

DTWSTL

Detroit Metropolitan Wayne County

Sun 5/18

10:31 am-6:41 pm

2 stops9h 10m

Lambert-St Louis

Sun 5/25

10:20 am-5:10 pm

1 stop5h 50m

$251

DetroitSt. Louis

DTW - STL

DTWSTL

Detroit Metropolitan Wayne County

Fri 9/5

6:00 am-10:40 am

1 stop5h 40m

Lambert-St Louis

Sun 9/7

5:30 pm-10:22 pm

1 stop3h 52m

$264

DetroitSt. Louis

DTW - STL

DTWSTL

Detroit Metropolitan Wayne County

Fri 5/9

6:38 am-9:15 am

2 stops27h 37m

Lambert-St Louis

Sun 5/11

10:10 am-11:20 pm

2 stops36h 10m

$358

DetroitSt. Louis

DTW - STL

DTWSTL

Detroit Metropolitan Wayne County

Thu 6/12

4:33 pm-5:04 pm

Nonstop1h 31m

$68

DetroitSt. Louis

DTW - STL

DTWSTL

Detroit Metropolitan Wayne County

Sun 5/18

12:54 pm-12:06 am

1 stop12h 12m

$86

DetroitSt. Louis

DTW - STL

DTWSTL

Detroit Metropolitan Wayne County

Mon 5/26

1:26 pm-9:52 pm

1 stop9h 26m

$91

Flights are sorted by cheapest round-trip flights first.

Deals found on 4/21

Showing 1-10 of 14 results

Compare providers for flights from Detroit to St. Louis

Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Detroit to St. Louis in April.

Provider	Price Accuracy	Trust Score*
Expedia	Price Accuracy1 star	Trust Score*3 stars
FlightHub	Price Accuracy3 stars	Trust Score*2 stars
eDreams	Price Accuracy3 stars	Trust Score*3 stars
Priceline	Price Accuracy1 star	Trust Score*3 stars

*The Trust Score is based on feedback from users after their booking experience. It measures overall satisfaction, helping us identify issues like hidden fees, problems during the ticketing process, and the quality of customer service. This score is our best indicator of the provider's quality and reliability.

Most accurate provider: When it comes to deals on Detroit-St. Louis flights, users find the pricing of FlightHub to be most consistent on Cheapflights vs. FlightHub Users can find the same prices on Detroit-St. Louis flight deals on Cheapflights vs. FlightHub >95% of the time. Price accuracy is based on data collected from Detroit-St. Louis flight searches over the past month and is updated monthly.
Most trusted provider: When it comes to deals on Detroit-St. Louis flights, Cheapflights users trust eDreams the most. eDreams has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Detroit-St. Louis flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.

Best time to book a flight from Detroit to St. Louis

Have a flexible travel schedule? Discover the best time to fly to St. Louis from Detroit with our price prediction graph.

Estimated round-trip price

Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Detroit to St. Louis

How far ahead should I book a flight from Detroit to St. Louis?

The price you pay for your flight from Detroit to St. Louis may vary depending on when you book. For the best chance of a lower fare, look to book 78 days in advance of your trip. Fares are likely to increase a fortnight or so before your departure date.

What is the cheapest month to book a flight from Detroit to St. Louis?

Currently, August is the cheapest month in which you can book a flight from Detroit to St. Louis (average of $311). Flying from Detroit to St. Louis in March is currently the most expensive (average of $356). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from DTT to STL?

When flying from Detroit to St. Louis, the time of day you fly usually plays a role in the price. Save by searching for a flight in the evening, which can drop the price by up to 9% versus a flight at noon.

Weekly flight availability from Detroit to St. Louis

The most flights from DTT to STL are scheduled on a Monday (14 on average). You will have fewer flight options on Saturday, which is when the least amount of flights are scheduled (9 on average).

Rainfall in St. Louis by month

In terms of precipitation, rainfall in St. Louis ranges from 2.2 - 4.7 inches per month. May is typically the wettest month, when rainfall can reach 4.7 in. February is typically the driest time to visit St. Louis when rainfall is around 2.2 in.

Temperature in St. Louis by month

If weather is an important factor for your trip to St. Louis, use this chart to help with planning. For those seeking warmer temperatures, July is the ideal time of year to visit, when temperatures reach an average of 80.6 F. Travelers looking to avoid the cold should look outside of January, when temperatures are typically at their lowest (around 32.0 F).

Reviews of airlines servicing St. Louis

Read reviews from past customers who have flown Southwest, Delta and United Airlines from Detroit to St. Louis. You can also see how each airline stacks up in terms of entertainment options, comfort, food, crew/service, and boarding process.

Southwest

8.0

Very good

4,287 reviews

Reviews

1 / 20

10.0

Excellent

Gina,Apr 2025

LAS - DEN

Good, the crew was friendly and helpful. The pilot had great skills in keeping the plane stable through rough turbulence. Smooth landing, too! Thank you!

Southwest

8.0

Very good

4,287 reviews

Southwest

8.0

Very good

4,287 reviews

Reviews

1 / 20

10.0

Excellent

Gina,Apr 2025

LAS - DEN

Good, the crew was friendly and helpful. The pilot had great skills in keeping the plane stable through rough turbulence. Smooth landing, too! Thank you!

Delta

8.0

Very good

7,920 reviews

Southwest

8.0

Very good

4,287 reviews

Reviews

1 / 20

10.0

Excellent

Gina,Apr 2025

LAS - DEN

Good, the crew was friendly and helpful. The pilot had great skills in keeping the plane stable through rough turbulence. Smooth landing, too! Thank you!

United Airlines

7.4

Good

8,684 reviews

Southwest

8.0

Very good

4,287 reviews

Reviews

1 / 20

10.0

Excellent

Gina,Apr 2025

LAS - DEN

Good, the crew was friendly and helpful. The pilot had great skills in keeping the plane stable through rough turbulence. Smooth landing, too! Thank you!

American Airlines

7.2

Good

10,000 reviews

Southwest

8.0

Very good

4,287 reviews

Reviews

1 / 20

10.0

Excellent

Gina,Apr 2025

LAS - DEN

Good, the crew was friendly and helpful. The pilot had great skills in keeping the plane stable through rough turbulence. Smooth landing, too! Thank you!

Spirit Airlines

6.3

Okay

7,940 reviews

Southwest

8.0

Very good

4,287 reviews

Reviews

1 / 20

10.0

Excellent

Gina,Apr 2025

LAS - DEN

Good, the crew was friendly and helpful. The pilot had great skills in keeping the plane stable through rough turbulence. Smooth landing, too! Thank you!

Related info for your journey

What airports do I use to fly from Detroit to St. Louis?
You will need to book a flight from Detroit All airports to Lambert-St Louis if you want to fly from Detroit to St. Louis. At least 5 different airlines have flights from All airports (DTT) to Lambert-St Louis (STL) on a regular basis. There are 13 flights to St. Louis from the Detroit airport per day. If you manage to book one that is nonstop, then you can expect the flight time from DTT to STL to be around 1h 30m.
What are the cheapest airlines flying from Detroit to St. Louis round-trip?
Our cheapest airline available from Detroit to St. Louis is American Airlines. Our recent data shows that you can find tickets from as low as $219 on this airline. Additional options worth looking into are Delta and Southwest, starting at $231 and $233 round-trip. You may be able to fly from Detroit to St. Louis for 33% less than the average price by searching for these airlines.
What are the cheapest airlines to fly from Detroit to St. Louis one-way?
$68 is the cheapest one-way deal found within the past few days, from Spirit Airlines. You may also be able to find cheap deals on Frontier and American Airlines, with prices starting from $86 and $91, respectively.
What are the most reliable airlines from Detroit to St. Louis?
Looking for the most reliable airlines to get you to your destination on time? Our data shows these are most likely to get you from Detroit to St. Louis on time: Aeromexico (91%), SkyWest Airlines (90%), Southwest (89%).
What are the cheapest flights from Detroit to St. Louis?
While on average a flight from Detroit to St. Louis is generally $291, our data shows the cheapest flight currently is $62. When looking at the most popular route, (Detroit Metropolitan Wayne County - Lambert-St Louis), you can expect to pay $138 for that flight.
Can I find deals for flights from Detroit to St. Louis that include hotel bookings?
Yes. In addition to deals on Detroit to St. Louis flights, Cheapflights offers vacation packages that include both flights and hotel.
How can I find direct flights from Detroit to St. Louis?
After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Detroit to St. Louis.
Can I find deals for business class flights from Detroit to St. Louis?
Yes. Cheapflights offers flight deals from Detroit to St. Louis by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.
What is the cheapest month to book a flight from Detroit to St. Louis?
Currently, August is the cheapest month in which you can book a flight from Detroit to St. Louis (average of $311). Flying from Detroit to St. Louis in March is currently the most expensive (average of $356). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

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Other flights to St. Louis

Top 5 airlines flying from Detroit to St. Louis

Airline	Cheapest	Average	Flexibility	On-time
Frontier	Cheapest$124	Average$200	FlexibilityNo cancel fee	On-time62%
American Airlines	Cheapest$179	Average$277	FlexibilityNo cancel fee	On-time71%
Delta	Cheapest$227	Average$313	FlexibilityNo cancel fee	On-timeN/A
Southwest	Cheapest$245	Average$304	FlexibilityNo cancel fee	On-time63%
United Airlines	Cheapest$298	Average$476	FlexibilityNo cancel fee	On-time69%

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$68+ Cheap flights from Detroit to St. Louis (DTT - STL)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 6/12. Fares are subject to change and may not be available on all flights or dates of travel.

Find cheap flights from Detroit to St. Louis with Cheapflights

1. Tell us where you want to go

2. Select your favorite providers

3. Compare prices and book

Cheapflights Tip: The best prices from Detroit All airports to Lambert-St Louis are usually found in March or June, booked 79 days in advance, depart on a Thursday or Friday and return on a Friday

Cheap flight deals from Detroit to St. Louis

Most accurate provider

Most trusted provider

Round-trip from

One-way from

Popular in

Cheapest in

Average price

Good round-trip deal

Good one-way deal

Find flight deals from Detroit to St. Louis

Cheapest flights from Detroit to St. LouisExplore the most affordable flight options available from Detroit to St. Louis. Find the lowest fares from popular airlines and budget airlines, with prices last updated on April 22, 2025.

Explore the most affordable flight options available from Detroit to St. Louis. Find the lowest fares from popular airlines and budget airlines, with prices last updated on April 22, 2025.

Cheapflights Fare Finder

Use the filters below to find and compare flights from Detroit to St. Louis that are best for you.

Compare providers for flights from Detroit to St. Louis

Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.

Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Detroit to St. Louis in April.

Best time to book a flight from Detroit to St. Louis

Have a flexible travel schedule? Discover the best time to fly to St. Louis from Detroit with our price prediction graph.

Cheapflights Insights

Everything you need to know about your flight from Detroit to St. Louis

How far ahead should I book a flight from Detroit to St. Louis?

Use this chart to determine the optimal time to book a round-trip flight from Detroit to St. Louis. Price data was last updated on April 18, 2025.

What is the cheapest month to book a flight from Detroit to St. Louis?

What is the cheapest time of day to fly from DTT to STL?

Find hourly flight availability from Detroit to St. Louis. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated April 22, 2025.

Weekly flight availability from Detroit to St. Louis

Explore weekly flight availability from Detroit to St. Louis. Discover flights operating on different days of the week, giving you the flexibility to choose a travel day that best fits your plans. Compare info to find the most convenient option for your journey. Data last updated April 22, 2025.

Rainfall in St. Louis by month

Plan your trip to St. Louis by taking into account the average rainfall totals by month.

Temperature in St. Louis by month

Plan your trip to St. Louis by taking into account the average temperature totals by month.

Reviews of airlines servicing St. Louis

Read reviews from past customers who have flown Southwest, Delta and United Airlines from Detroit to St. Louis. You can also see how each airline stacks up in terms of entertainment options, comfort, food, crew/service, and boarding process.

Related info for your journey

Find useful and relevant information for your journey from Detroit to St. Louis. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

What airports do I use to fly from Detroit to St. Louis?

What are the cheapest airlines flying from Detroit to St. Louis round-trip?

What are the cheapest airlines to fly from Detroit to St. Louis one-way?

What are the most reliable airlines from Detroit to St. Louis?

What are the cheapest flights from Detroit to St. Louis?

Can I find deals for flights from Detroit to St. Louis that include hotel bookings?

How can I find direct flights from Detroit to St. Louis?

Can I find deals for business class flights from Detroit to St. Louis?

What is the cheapest month to book a flight from Detroit to St. Louis?

Traveling to a place near Detroit?

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Alternative routes for Detroit to St. Louis

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Top 5 airlines flying from Detroit to St. Louis

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Cheapest flights from Detroit to St. Louis
Explore the most affordable flight options available from Detroit to St. Louis. Find the lowest fares from popular airlines and budget airlines, with prices last updated on April 22, 2025.