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$81+ Cheap flights from Des Moines to St. Louis (DSM - STL)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 3/19. Fares are subject to change and may not be available on all flights or dates of travel.
DSM — STL
ene. 21 — ene. 281
mar. 1/21
mar. 1/28
1 adult, Economy
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Cheap flight deals from Des Moines to St. Louis

Discover tips and strategies to find the most affordable flight options for your journey from Des Moines (DSM) to St. Louis (STL). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated enero 16, 2025.

Most accurate provider

FlightHub
3 stars

Most trusted provider

FlightHub
3 stars

Round-trip from

$309
(Southwest)

One-way from

$81
(Frontier)

Popular in

September

Cheapest in

August

Average price

$434
Provider with most accurate pricing for Des Moines-Lambert-St Louis flight deals.
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Provider most trusted by Cheapflights users for Des Moines-Lambert-St Louis flights.
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From Des Moines to Lambert-St Louis
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One-way flight from Des Moines to Lambert-St Louis
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High demand for flights, 3% potential price rise
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Best time to find cheap flights, 5% potential price drop
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Average for round-trip flights in January 2025
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Find flight deals from Des Moines to St. Louis

Cheapest flights from Des Moines to St. Louis
Explore the most affordable flight options available from Des Moines to St. Louis. Find the lowest fares from popular airlines and budget airlines, with prices last updated on enero 16, 2025.

This Southwest deal was found by Cheapflights users on 1/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
vie. 2/215:30 amDSM - STL
Nonstop1h 20mSouthwest
mar. 2/2510:00 amSTL - DSM
1 stop9h 00mSouthwest
Deal found 1/16$309
This American Airlines deal was found by Cheapflights users on 1/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
sáb. 3/16:00 pmDSM - STL
1 stop4h 14mAmerican Airlines
sáb. 3/85:37 pmSTL - DSM
1 stop6h 12mAmerican Airlines
Deal found 1/15$310
This Delta deal was found by Cheapflights users on 1/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
vie. 2/217:00 amDSM - STL
1 stop3h 59mDelta
mar. 2/256:43 amSTL - DSM
2 stops9h 47mDelta
Deal found 1/16$314
This Mytrip deal was found by Cheapflights users on 1/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
sáb. 3/13:04 pmDSM - STL
3 stops21h 06mMultiple Airlines
sáb. 3/810:24 amSTL - DSM
2 stops25h 27mMultiple Airlines
Deal found 1/15$453
This United Airlines deal was found by Cheapflights users on 1/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
sáb. 3/18:00 amDSM - STL
2 stops12h 44mUnited Airlines
sáb. 3/88:00 amSTL - DSM
1 stop6h 52mUnited Airlines
Deal found 1/15$472

Find flights from Des Moines to St. Louis within your budget

Customize your flight search to find flights from Des Moines to St. Louis that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated enero 16, 2025.

Fly from

Any airport

Fly to

Any airport

Route

Depart

Return

Price

Des MoinesSt. Louis

DSM - STL

DSMSTL

Des Moines

vie. 2/21

5:30 am-6:50 am

Nonstop1h 20m

Lambert-St Louis

mar. 2/25

10:00 am-7:00 pm

1 stop9h 00m

$309

Des MoinesSt. Louis

DSM - STL

DSMSTL

Des Moines

sáb. 3/1

6:00 pm-10:14 pm

1 stop4h 14m

Lambert-St Louis

sáb. 3/8

5:37 pm-11:49 pm

1 stop6h 12m

$310

Des MoinesSt. Louis

DSM - STL

DSMSTL

Des Moines

vie. 2/21

7:00 am-10:59 am

1 stop3h 59m

Lambert-St Louis

mar. 2/25

6:43 am-4:30 pm

2 stops9h 47m

$314

Des MoinesSt. Louis

DSM - STL

DSMSTL

Des Moines

sáb. 3/1

3:04 pm-12:10 pm

3 stops21h 06m

Lambert-St Louis

sáb. 3/8

10:24 am-11:51 am

2 stops25h 27m

$453

Des MoinesSt. Louis

DSM - STL

DSMSTL

Des Moines

sáb. 3/1

8:00 am-8:44 pm

2 stops12h 44m

Lambert-St Louis

sáb. 3/8

8:00 am-2:52 pm

1 stop6h 52m

$472

Des MoinesSt. Louis

DSM - STL

DSMSTL

Des Moines

mié. 3/19

6:57 pm-7:58 am

1 stop13h 01m

$81

Des MoinesSt. Louis

DSM - STL

DSMSTL

Des Moines

sáb. 2/15

5:34 am-11:46 am

1 stop6h 12m

$155

Des MoinesSt. Louis

DSM - STL

DSMSTL

Des Moines

dom. 2/9

6:30 am-7:50 am

Nonstop1h 20m

$166

Des MoinesSt. Louis

DSM - STL

DSMSTL

Des Moines

lun. 3/17

8:10 am-2:23 pm

1 stop6h 13m

$185

Des MoinesSt. Louis

DSM - STL

DSMSTL

Des Moines

dom. 3/16

6:16 pm-10:18 pm

1 stop4h 02m

$236

Flights are sorted by cheapest round-trip flights first.

Deals found on 1/16

Compare providers for flights from Des Moines to St. Louis

Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Des Moines to St. Louis in January.
ProviderPrice AccuracyTrust Score*
ExpediaPrice Accuracy1 starTrust Score*3 stars
FlightHubPrice Accuracy3 starsTrust Score*3 stars
eDreamsPrice Accuracy3 starsTrust Score*3 stars
PricelinePrice Accuracy2 starsTrust Score*3 stars

*The Trust Score is based on feedback from users after their booking experience. It measures overall satisfaction, helping us identify issues like hidden fees, problems during the ticketing process, and the quality of customer service. This score is our best indicator of the provider's quality and reliability.

  • Most accurate provider: When it comes to deals on Des Moines-St. Louis flights, users find the pricing of FlightHub to be most consistent on Cheapflights vs. FlightHub Users can find the same prices on Des Moines-St. Louis flight deals on Cheapflights vs. FlightHub >95% of the time. Price accuracy is based on data collected from Des Moines-St. Louis flight searches over the past month and is updated monthly.
  • Most trusted provider: When it comes to deals on Des Moines-St. Louis flights, Cheapflights users trust FlightHub the most. FlightHub has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Des Moines-St. Louis flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.

Best time to book a flight from Des Moines to St. Louis

Have a flexible travel schedule? Discover the best time to fly to St. Louis from Des Moines with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Travel insights for flights from Des Moines to St. Louis

Get recent, data-driven insights about flights from Des Moines to St. Louis including ideal travel times, pricing trends, and more.

What is the cheapest month to book a flight from Des Moines to St. Louis?

Currently, August is the cheapest month in which you can book a flight from Des Moines to St. Louis (average of $311). Flying from Des Moines to St. Louis in March is currently the most expensive (average of $356). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from DSM to STL?

Find hourly flight availability from Des Moines to St. Louis. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated enero 16, 2025.

One of the essential ways to save on airfare from Des Moines to St. Louis is to remain as flexible as possible. Flights that are at noon tend to be the most expensive. A flight in the morning could potentially save you up to 4% on airfare.

Rainfall in St. Louis by month

Plan your trip to St. Louis by taking into account the average rainfall totals by month.

In terms of precipitation, rainfall in St. Louis ranges from 2.2 - 4.7 inches per month. May is typically the wettest month, when rainfall can reach 4.7 in. February is typically the driest time to visit St. Louis when rainfall is around 2.2 in.

Temperature in St. Louis by month

Plan your trip to St. Louis by taking into account the average temperature totals by month.

If weather is an important factor for your trip to St. Louis, use this chart to help with planning. For those seeking warmer temperatures, July is the ideal time of year to visit, when temperatures reach an average of 80.6 F. Travelers looking to avoid the cold should look outside of January, when temperatures are typically at their lowest (around 32.0 F).

Reviews of airlines servicing St. Louis

Get insights into the airlines that provide service to St. Louis. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to St. Louis. Reviews last updated enero 16, 2025.
Southwest
8.1
Very good
4,659 reviews

Overall

8.1

Boarding

8.2

Entertainment

7.7

Food

7.2

Crew

8.7

Comfort

8.1

Reviews

1 / 10

We BARELY made the connection and when we got onboard we were treated like disobedient children who should have arrived earlier because we had to ask other passengers to move so we could sit with our kids. The flight attendants on the first flight were nice but the second one, they were snippy and fairly rude.

Southwest
8.1
Very good
4,659 reviews
Southwest
8.1
Very good
4,659 reviews

Overall

8.1

Boarding

8.2

Entertainment

7.7

Food

7.2

Crew

8.7

Comfort

8.1

Reviews

1 / 10

We BARELY made the connection and when we got onboard we were treated like disobedient children who should have arrived earlier because we had to ask other passengers to move so we could sit with our kids. The flight attendants on the first flight were nice but the second one, they were snippy and fairly rude.

Delta
8.0
Very good
8,511 reviews
Southwest
8.1
Very good
4,659 reviews

Overall

8.1

Boarding

8.2

Entertainment

7.7

Food

7.2

Crew

8.7

Comfort

8.1

Reviews

1 / 10

We BARELY made the connection and when we got onboard we were treated like disobedient children who should have arrived earlier because we had to ask other passengers to move so we could sit with our kids. The flight attendants on the first flight were nice but the second one, they were snippy and fairly rude.

United Airlines
7.4
Good
8,964 reviews
Southwest
8.1
Very good
4,659 reviews

Overall

8.1

Boarding

8.2

Entertainment

7.7

Food

7.2

Crew

8.7

Comfort

8.1

Reviews

1 / 10

We BARELY made the connection and when we got onboard we were treated like disobedient children who should have arrived earlier because we had to ask other passengers to move so we could sit with our kids. The flight attendants on the first flight were nice but the second one, they were snippy and fairly rude.

American Airlines
7.2
Good
10,000 reviews
Southwest
8.1
Very good
4,659 reviews

Overall

8.1

Boarding

8.2

Entertainment

7.7

Food

7.2

Crew

8.7

Comfort

8.1

Reviews

1 / 10

We BARELY made the connection and when we got onboard we were treated like disobedient children who should have arrived earlier because we had to ask other passengers to move so we could sit with our kids. The flight attendants on the first flight were nice but the second one, they were snippy and fairly rude.

Frontier
6.1
Okay
3,435 reviews
Southwest
8.1
Very good
4,659 reviews

Overall

8.1

Boarding

8.2

Entertainment

7.7

Food

7.2

Crew

8.7

Comfort

8.1

Reviews

1 / 10

We BARELY made the connection and when we got onboard we were treated like disobedient children who should have arrived earlier because we had to ask other passengers to move so we could sit with our kids. The flight attendants on the first flight were nice but the second one, they were snippy and fairly rude.

Related info for your journey

Find useful and relevant information for your journey from Des Moines to St. Louis. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airports do I use to fly from Des Moines to St. Louis?

    Lambert-St Louis is the airport most travelers will use when flying to St. Louis from Des Moines. Booking flights from Des Moines (DSM) to Lambert-St Louis (STL) should be relatively easy as there is 1 daily flight to St. Louis from 3 different airlines. 1h 10m is how long a flight from Des Moines to Lambert-St Louis will take if you book a nonstop flight.

  • How popular is this Des Moines to St. Louis flight route?

    This flight path from Des Moines to Lambert-St Louis was viewed by 8 users in the past month. Keep an eye out for changes in search interest prior to high and low season.

  • What are the cheapest airlines flying from Des Moines to St. Louis round-trip?

    Cheapflights users have booked flights from Des Moines to St. Louis round-trip from $309. Other airlines that can offer you cheap pricing are American Airlines, from $310, and Delta, from $314. Users have found that Southwest is 27% cheaper than the other options available to this destination.

  • What are the cheapest airlines to fly from Des Moines to St. Louis one-way?

    To fly one-way, consider booking your trip with Frontier, which is currently one of the cheapest options available, starting at $81. Delta flights start at $155 while deals on Southwest start at $171 one-way.

  • What are the cheapest flights from Des Moines to St. Louis?

    While on average a flight from Des Moines to St. Louis is generally $383, our data shows the cheapest flight currently is $174. When looking at the most popular route, (Des Moines - Lambert-St Louis), you can expect to pay $309 for that flight.

  • Can I find deals for flights from Des Moines to St. Louis that include hotel bookings?

    Yes. In addition to deals on Des Moines to St. Louis flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Des Moines to St. Louis?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Des Moines to St. Louis.

  • Can I find deals for business class flights from Des Moines to St. Louis?

    Yes. Cheapflights offers flight deals from Des Moines to St. Louis by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Des Moines to St. Louis?

    Currently, August is the cheapest month in which you can book a flight from Des Moines to St. Louis (average of $311). Flying from Des Moines to St. Louis in March is currently the most expensive (average of $356). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Traveling to a place near Des Moines?

Book flights to Des Moines if you plan to visit one of these locations
Fenton
Fairview Heights
Maryland Heights
Collinsville
Wentzville
Eureka
St. Peters
Festus
Alton
Farmington
Chesterfield

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Top 3 airlines flying from Des Moines to St. Louis

Discover the top 3 airlines that operate flights from Des Moines to St. Louis. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated enero 16, 2025.
AirlineCheapestAverageFlexibilityOn-time
DeltaCheapest$155Average$470FlexibilityNo cancel feeOn-timeN/A
SouthwestCheapest$168Average$326FlexibilityNo cancel feeOn-time63%
American AirlinesCheapest$257Average$435FlexibilityNo cancel feeOn-time71%
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