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Spartanburg

$85+ Cheap flights from Myrtle Beach (MYR) to Spartanburg, SC

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 1/13. Fares are subject to change and may not be available on all flights or dates of travel.
MYR — CLT
Jan 13 — Jan 201
Tue 1/13
Tue 1/20
1 adult, Economy
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Cheap flight deals from Myrtle Beach to Spartanburg

Cheapest flights from Myrtle Beach to Spartanburg
Explore the most affordable flight options available from Myrtle Beach to Spartanburg. Find the lowest fares from popular airlines and budget airlines, with prices last updated on December 14, 2025.

This American Airlines deal was found by Cheapflights users on 12/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/246:00 amMYR - CLT
Nonstop1h 12mAmerican Airlines
Wed 12/249:29 amCLT - MYR
1 stop24h 39mAmerican Airlines
Deal found 12/12$275
This Kiwi.com deal was found by Cheapflights users on 12/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/319:54 amMYR - CLT
1 stop10h 39mSpirit Airlines
Sat 1/39:05 amCLT - MYR
1 stop23h 44mSpirit Airlines
Deal found 12/12$288
This Kiwi.com deal was found by Cheapflights users on 12/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/317:13 pmMYR - CLT
2 stops16h 09mMultiple Airlines
Sat 1/39:05 amCLT - MYR
1 stop23h 44mMultiple Airlines
Deal found 12/12$330
This Kiwi.com deal was found by Cheapflights users on 12/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 12/287:32 pmMYR - CLT
1 stop25h 26mMultiple Airlines
Thu 1/19:04 pmCLT - MYR
1 stop11h 45mMultiple Airlines
Deal found 12/13$353
This American Airlines deal was found by Cheapflights users on 12/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/1311:39 amMYR - CLT
1 stop18h 50mAmerican Airlines
Sun 12/149:20 amCLT - MYR
Nonstop1h 22mAmerican Airlines
Deal found 12/12$355
This American Airlines deal was found by Cheapflights users on 12/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/3112:48 pmMYR - CLT
Nonstop1h 07mAmerican Airlines
Sat 1/311:09 amCLT - MYR
Nonstop1h 09mAmerican Airlines
Deal found 12/12$356
This Kiwi.com deal was found by Cheapflights users on 12/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 12/287:32 pmMYR - CLT
2 stops27h 57mSpirit Airlines
Thu 1/19:00 amCLT - MYR
1 stop9h 08mSpirit Airlines
Deal found 12/13$372
This Kiwi.com deal was found by Cheapflights users on 12/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 12/212:59 pmMYR - CLT
2 stops18h 40mMultiple Airlines
Mon 12/229:38 pmCLT - MYR
1 stop20h 30mMultiple Airlines
Deal found 12/13$378
This Kiwi.com deal was found by Cheapflights users on 12/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 12/219:54 amMYR - CLT
1 stop10h 39mSpirit Airlines
Mon 12/229:38 pmCLT - MYR
1 stop20h 30mSpirit Airlines
Deal found 12/13$385
This American Airlines deal was found by Cheapflights users on 12/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/276:00 amMYR - CLT
Nonstop1h 12mAmerican Airlines
Wed 12/318:15 amCLT - MYR
Nonstop1h 05mAmerican Airlines
Deal found 12/12$431

Find flight deals from Myrtle Beach to Spartanburg

Keep the following information in mind while searching for Myrtle Beach to Spartanburg flight deals. Data was last updated December 14, 2025.

Most accurate provider

eDreams
3 stars

Most trusted provider

eDreams
3 stars

Round-trip from

$166
(Kiwi.com)

One-way from

$85
(Kiwi.com)

Popular in

October

Cheapest in

August

Average price

$366
Provider with most accurate pricing for Myrtle Beach Intl-Charlotte Douglas flight deals.
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Provider most trusted by Cheapflights users for Myrtle Beach Intl-Charlotte Douglas flights.
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From Myrtle Beach Intl to Spartanburg
Search Deals
One-way flight from Myrtle Beach Intl to Spartanburg
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Highest demand for flights based on searches. 19% potential increase in price ($107 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 6% potential price decrease ($28 potential savings vs. average RT price).
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Average for round-trip flights in December 2025
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Cheapflights Fare Finder

 
Customize your flight search to find flights from Myrtle Beach to Spartanburg that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated December 14, 2025.
Use the filters below to find and compare flights from Myrtle Beach to Spartanburg that are best for you.

Fly from

Myrtle Beach

Fly to

Spartanburg

Route

Depart

Return

Price

Myrtle BeachCharlotte

MYR - CLT

MYRCLT

Myrtle Beach Intl

Sat 2/21

6:15 am-2:17 pm

1 stop8h 02m

Charlotte Douglas

Sat 2/28

5:54 pm-8:58 am

1 stop15h 04m

$176

Myrtle BeachCharlotte

MYR - CLT

MYRCLT

Myrtle Beach Intl

Sat 2/21

6:15 am-2:17 pm

1 stop8h 02m

Charlotte Douglas

Fri 2/27

7:05 pm-8:13 am

1 stop13h 08m

$178

Myrtle BeachCharlotte

MYR - CLT

MYRCLT

Myrtle Beach Intl

Fri 1/9

9:59 pm-7:46 pm

1 stop21h 47m

Charlotte Douglas

Fri 1/16

9:07 pm-2:42 pm

1 stop17h 35m

$188

Myrtle BeachCharlotte

MYR - CLT

MYRCLT

Myrtle Beach Intl

Thu 2/19

9:09 am-6:02 pm

1 stop8h 53m

Charlotte Douglas

Sat 2/28

5:54 pm-8:58 am

1 stop15h 04m

$199

Myrtle BeachCharlotte

MYR - CLT

MYRCLT

Myrtle Beach Intl

Sat 2/14

3:59 pm-11:59 pm

1 stop8h 00m

Charlotte Douglas

Mon 2/16

9:07 pm-11:57 pm

1 stop26h 50m

$210

Myrtle BeachCharlotte

MYR - CLT

MYRCLT

Myrtle Beach Intl

Sat 2/21

6:15 am-2:17 pm

1 stop8h 02m

Charlotte Douglas

Thu 2/26

7:00 am-8:51 pm

2 stops13h 51m

$215

Myrtle BeachCharlotte

MYR - CLT

MYRCLT

Myrtle Beach Intl

Wed 2/18

6:15 am-2:17 pm

1 stop8h 02m

Charlotte Douglas

Thu 2/26

7:00 am-8:51 pm

2 stops13h 51m

$216

Myrtle BeachCharlotte

MYR - CLT

MYRCLT

Myrtle Beach Intl

Fri 1/9

10:00 am-11:59 pm

1 stop13h 59m

Charlotte Douglas

Sun 1/11

5:38 pm-2:42 pm

1 stop21h 04m

$218

Myrtle BeachCharlotte

MYR - CLT

MYRCLT

Myrtle Beach Intl

Thu 2/19

12:39 pm-11:54 pm

2 stops11h 15m

Charlotte Douglas

Wed 2/25

9:21 am-2:44 pm

1 stop5h 23m

$220

Myrtle BeachCharlotte

MYR - CLT

MYRCLT

Myrtle Beach Intl

Fri 1/9

9:59 pm-4:54 pm

2 stops18h 55m

Charlotte Douglas

Fri 1/16

9:06 am-2:42 pm

1 stop5h 36m

$222

Flights are sorted by cheapest round-trip flights first.

Deals found on 12/12

Showing 1-10 of 21 results
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Best time to book a flight from Myrtle Beach to Spartanburg

Have a flexible travel schedule? Discover the best time to fly to Spartanburg from Myrtle Beach with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Myrtle Beach to Spartanburg

What is the cheapest month to book a flight from Myrtle Beach to Spartanburg?

Currently, February is the cheapest month in which you can book a flight from Myrtle Beach to Spartanburg (average of $191). Flying from Myrtle Beach to Spartanburg in November is currently the most expensive (average of $448). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from MYR to SB1?

Find hourly flight availability from Myrtle Beach to Spartanburg. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated December 14, 2025.

One of the essential ways to save on airfare from Myrtle Beach to Spartanburg is to remain as flexible as possible. Flights that are at noon tend to be the most expensive. A flight in the evening could potentially save you up to 51% on airfare.

What is the cheapest day to fly from Myrtle Beach to Spartanburg?

Use this chart to determine the cheapest time to fly round-trip from Myrtle Beach to Spartanburg. Price data was last updated on December 16, 2024.

Travelers seeking maximum savings on their Myrtle Beach to Spartanburg flight should consider departing on Wednesday mornings when fares are most often at their lowest. Sunday at noon flights should be avoided if possible as fares are typically the most expensive at this time.

Reviews of airlines servicing Spartanburg

Get insights into the airlines that provide service to Spartanburg. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Spartanburg. Reviews last updated December 14, 2025.
Read through reviews of airlines operating flights from Myrtle Beach to Spartanburg, such as American Airlines. Reviews also offer insight into each airline's entertainment options, comfort, food, crew/service, and boarding process.
American Airlines
7.2
Good
11,054 reviews

Comfort

7.2

Entertainment

6.9

Boarding

7.5

Food

6.5

Crew

8.0

Overall

7.2

Reviews

1 / 20
10.0
Excellent

Jeremy,Dec 2025

OKC - CLT

Was an okay flight. Had extra seat empty beside me so was able to stretch a bit
American Airlines
7.2
Good
11,054 reviews
American Airlines
7.2
Good
11,054 reviews

Comfort

7.2

Entertainment

6.9

Boarding

7.5

Food

6.5

Crew

8.0

Overall

7.2

Reviews

1 / 20
10.0
Excellent

Jeremy,Dec 2025

OKC - CLT

Was an okay flight. Had extra seat empty beside me so was able to stretch a bit

Related info for your journey

Find useful and relevant information for your journey from Myrtle Beach to Spartanburg. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly from for flights from Myrtle Beach to Spartanburg?

    For a flight from Myrtle Beach to Spartanburg, you will be flying from Myrtle Beach Intl. Myrtle Beach Intl (MYR) is just 2.1 mi from the center of the city. Myrtle Beach Intl is the only Myrtle Beach airport and it handles 6 outbound flights to Spartanburg per day. 1 airline has flights to Spartanburg from Myrtle Beach Intl on a regular basis.

  • How popular is this Myrtle Beach to Spartanburg flight route?

    Flights from Myrtle Beach Intl to Spartanburg have been viewed 7 times in the past calendar month.

  • How long is the flight from Myrtle Beach to Spartanburg?

    There are many flights that can get you from Myrtle Beach to Spartanburg in 8h 02m. Fly via Spirit Airlines to get the fastest option. Airlines will cover a distance of 157 mi.

  • What are the most reliable airlines from Myrtle Beach to Spartanburg?

    No one likes to see their flight delayed. When booking a flight from Myrtle Beach to Spartanburg consider choosing Envoy Air (100%), PSA Airlines (90%) or American Airlines (86%) as they are the most reliable in getting you off to your destination on time.

  • What are the cheapest flights from Myrtle Beach to Spartanburg?

    On average you can expect to pay $1,016 for a flight from Myrtle Beach to Spartanburg. The cheapest flight overall is $124 while the most popular route, (Myrtle Beach Intl - Charlotte Douglas) is currently priced at $188.

  • Can I find deals for flights from Myrtle Beach to Spartanburg that include hotel bookings?

    Yes. In addition to deals on Myrtle Beach to Spartanburg flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Myrtle Beach to Spartanburg?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Myrtle Beach to Spartanburg.

  • Can I find deals for business class flights from Myrtle Beach to Spartanburg?

    Yes. Cheapflights offers flight deals from Myrtle Beach to Spartanburg by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Myrtle Beach to Spartanburg?

    Currently, February is the cheapest month in which you can book a flight from Myrtle Beach to Spartanburg (average of $191). Flying from Myrtle Beach to Spartanburg in November is currently the most expensive (average of $448). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

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Top airline flying from Myrtle Beach to Spartanburg

Discover the top airline that operate flights from Myrtle Beach to Spartanburg. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated December 14, 2025.
AirlineCheapestAverageFlexibilityOn-time
American AirlinesCheapest$176Average$346FlexibilityNo cancel feeOn-time71%

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