Spartanburg

$115+ Cheap flights from Knoxville (TYS) to Spartanburg, SC

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 4/23. Fares are subject to change and may not be available on all flights or dates of travel.
TYS — CLT
Apr 2 — Apr 91
We work with more than 300 partners to bring you better travel deals

Find cheap flights from Knoxville to Spartanburg with Cheapflights

1. Tell us where you want to go
Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”
2. Select your favorite providers
We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.
3. Compare prices and book
Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.

Cheap flight deals from Knoxville to Spartanburg

Keep the following information in mind while searching for Knoxville to Spartanburg flight deals. Data was last updated March 28, 2025.

Most accurate provider

FlightHub
3 stars

Most trusted provider

FlightHub
3 stars

Round-trip from

$202
(Mytrip)

One-way from

$115
(Mytrip)

Popular in

August

Cheapest in

April

Average price

$507
Provider with most accurate pricing for Knoxville McGhee Tyson-Charlotte Douglas flight deals.
Provider most trusted by Cheapflights users for Knoxville McGhee Tyson-Charlotte Douglas flights.
From Knoxville McGhee Tyson to Spartanburg
One-way flight from Knoxville McGhee Tyson to Spartanburg
Highest demand for flights based on searches. 8% potential increase in price ($48 potential increase over avg. RT price).
Cheapest flight prices on average. 1% potential price decrease ($9 potential savings vs. average RT price).
Average for round-trip flights in March 2025

Find flight deals from Knoxville to Spartanburg

Cheapest flights from Knoxville to Spartanburg
Explore the most affordable flight options available from Knoxville to Spartanburg. Find the lowest fares from popular airlines and budget airlines, with prices last updated on March 28, 2025.

This Mytrip deal was found by Cheapflights users on 3/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 4/211:29 pmTYS - CLT
1 stop20h 43mMultiple Airlines
Tue 4/225:43 pmCLT - TYS
1 stop20h 20mMultiple Airlines
Deal found 3/26$202
This American Airlines deal was found by Cheapflights users on 3/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 4/217:32 pmTYS - CLT
1 stop16h 22mAmerican Airlines
Tue 4/222:35 pmCLT - TYS
Nonstop1h 15mAmerican Airlines
Deal found 3/26$257
This United deal was found by Cheapflights users on 3/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/17:00 amTYS - CLT
1 stop14h 21mUnited Airlines
Fri 5/25:30 pmCLT - TYS
2 stops21h 05mUnited Airlines
Deal found 3/26$495
This Delta deal was found by Cheapflights users on 3/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/178:45 amTYS - CLT
1 stop6h 09mDelta
Sun 4/207:37 pmCLT - TYS
1 stop4h 11mDelta
Deal found 3/26$589

Cheapflights Fare Finder

Customize your flight search to find flights from Knoxville to Spartanburg that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated March 28, 2025.
Use the filters below to find and compare flights from Knoxville to Spartanburg that are best for you.

Fly from

Knoxville

Fly to

Spartanburg

Route

Depart

Return

Price

KnoxvilleCharlotte

TYS - CLT

TYSCLT

Knoxville McGhee Tyson

Mon 4/21

1:29 pm-10:12 am

1 stop20h 43m

Charlotte Douglas

Tue 4/22

5:43 pm-2:03 pm

1 stop20h 20m

$202

KnoxvilleCharlotte

TYS - CLT

TYSCLT

Knoxville McGhee Tyson

Mon 4/21

7:32 pm-11:54 am

1 stop16h 22m

Charlotte Douglas

Tue 4/22

2:35 pm-3:50 pm

Nonstop1h 15m

$257

KnoxvilleCharlotte

TYS - CLT

TYSCLT

Knoxville McGhee Tyson

Thu 5/1

7:00 am-9:21 pm

1 stop14h 21m

Charlotte Douglas

Fri 5/2

5:30 pm-2:35 pm

2 stops21h 05m

$495

KnoxvilleCharlotte

TYS - CLT

TYSCLT

Knoxville McGhee Tyson

Thu 4/17

8:45 am-2:54 pm

1 stop6h 09m

Charlotte Douglas

Sun 4/20

7:37 pm-11:48 pm

1 stop4h 11m

$589

KnoxvilleCharlotte

TYS - CLT

TYSCLT

Knoxville McGhee Tyson

Wed 4/23

9:00 am-12:27 am

1 stop15h 27m

$115

KnoxvilleCharlotte

TYS - CLT

TYSCLT

Knoxville McGhee Tyson

Fri 6/6

5:12 pm-5:00 pm

1 stop23h 48m

$214

KnoxvilleCharlotte

TYS - CLT

TYSCLT

Knoxville McGhee Tyson

Fri 6/6

7:25 pm-10:12 am

2 stops14h 47m

$480

Flights are sorted by cheapest round-trip flights first.

Deals found on 3/26

Best time to book a flight from Knoxville to Spartanburg

Have a flexible travel schedule? Discover the best time to fly to Spartanburg from Knoxville with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Knoxville to Spartanburg

What is the cheapest month to book a flight from Knoxville to Spartanburg?

Currently, August is the cheapest month in which you can book a flight from Knoxville to Spartanburg (average of $248). Flying from Knoxville to Spartanburg in March is currently the most expensive (average of $328). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from TYS to SB1?

Find hourly flight availability from Knoxville to Spartanburg. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated March 28, 2025.

Regardless of the time of day you decide to fly, the ticket price will remain around the same. Book flights from Knoxville to Spartanburg as you normally would.

What is the cheapest day to fly from Knoxville to Spartanburg?

Use this chart to determine the cheapest time to fly round-trip from Knoxville to Spartanburg. Price data was last updated on December 16, 2024.

Travelers seeking maximum savings on their Knoxville to Spartanburg flight should consider departing on Thursday evenings when fares are most often at their lowest. Sunday at noon flights should be avoided if possible as fares are typically the most expensive at this time.

Weekly flight availability from Knoxville to Spartanburg

Explore weekly flight availability from Knoxville to Spartanburg. Discover flights operating on different days of the week, giving you the flexibility to choose a travel day that best fits your plans. Compare info to find the most convenient option for your journey. Data last updated March 28, 2025.

The most flights from TYS to SB1 are scheduled on a Thursday (8 on average). You will have fewer flight options on Monday, which is when the least amount of flights are scheduled (2 on average).

Rainfall in Spartanburg by month

Plan your trip to Spartanburg by taking into account the average rainfall totals by month.

In terms of precipitation, rainfall in Spartanburg ranges from 3.0 - 4.2 inches per month. August is typically the wettest month, when rainfall can reach 4.2 in. April is typically the driest time to visit Spartanburg when rainfall is around 3.0 in.

Temperature in Spartanburg by month

Plan your trip to Spartanburg by taking into account the average temperature totals by month.

If weather is an important factor for your trip to Spartanburg, use this chart to help with planning. For those seeking warmer temperatures, July is the ideal time of year to visit, when temperatures reach an average of 78.8 F. Travelers looking to avoid the cold should look outside of January, when temperatures are typically at their lowest (around 41.0 F).

Reviews of airlines servicing Spartanburg

Get insights into the airlines that provide service to Spartanburg. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Spartanburg. Reviews last updated March 28, 2025.
See what other customers who have flown with Delta, United Airlines and American Airlines from Knoxville to Spartanburg have to say. You can also see how each airline stacks up in terms of entertainment options, comfort, food, crew/service, and boarding process.
8.0
Very good

Crew

8.5

Food

7.3

Entertainment

7.9

Overall

8.0

Comfort

8.0

Boarding

8.2

Reviews

1 / 20
10.0
Excellent

Aaron,Oct 2024

TUS - LAX

Delta has consistently been the best U.S. airline for my travels and this flight was no exception
8.0
Very good
8.0
Very good

Crew

8.5

Food

7.3

Entertainment

7.9

Overall

8.0

Comfort

8.0

Boarding

8.2

Reviews

1 / 20
10.0
Excellent

Aaron,Oct 2024

TUS - LAX

Delta has consistently been the best U.S. airline for my travels and this flight was no exception
8.0
Very good

Crew

8.5

Food

7.3

Entertainment

7.9

Overall

8.0

Comfort

8.0

Boarding

8.2

Reviews

1 / 20
10.0
Excellent

Aaron,Oct 2024

TUS - LAX

Delta has consistently been the best U.S. airline for my travels and this flight was no exception
8.0
Very good

Crew

8.5

Food

7.3

Entertainment

7.9

Overall

8.0

Comfort

8.0

Boarding

8.2

Reviews

1 / 20
10.0
Excellent

Aaron,Oct 2024

TUS - LAX

Delta has consistently been the best U.S. airline for my travels and this flight was no exception

Related info for your journey

Find useful and relevant information for your journey from Knoxville to Spartanburg. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
  • What airport do you fly from for flights from Knoxville to Spartanburg?

    If you book a flight to Spartanburg from Knoxville, you will be flying from McGhee Tyson, which is the city’s only airport. Knoxville McGhee Tyson (TYS) is located 11.3 mi from the center of Knoxville. There are 4 flights from McGhee Tyson to Spartanburg per day from 2 different airlines.

  • What are the cheapest airlines to fly from Knoxville to Spartanburg one-way?

    The cheapest airlines for a one-way flight from Knoxville to Spartanburg are American Airlines ($214), Delta ($453), and United Airlines ($480).

  • What are the most reliable airlines from Knoxville to Spartanburg?

    Before booking your flight to Spartanburg from Knoxville, check out the most reliable airlines to get you to your destination on time: Piedmont Airlines (77%), PSA Airlines (77%), American Airlines( 77%).

  • What are the cheapest flights from Knoxville to Spartanburg?

    The cheapest flight price from Knoxville to Spartanburg is $99. On average you can expect to pay $505. The most popular route, (Knoxville McGhee Tyson - Charlotte Douglas), can usually be booked for $202.

  • Can I find deals for flights from Knoxville to Spartanburg that include hotel bookings?

    Yes. In addition to deals on Knoxville to Spartanburg flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Knoxville to Spartanburg?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Knoxville to Spartanburg.

  • Can I find deals for business class flights from Knoxville to Spartanburg?

    Yes. Cheapflights offers flight deals from Knoxville to Spartanburg by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Knoxville to Spartanburg?

    Currently, August is the cheapest month in which you can book a flight from Knoxville to Spartanburg (average of $248). Flying from Knoxville to Spartanburg in March is currently the most expensive (average of $328). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Browse thousands of different options on Cheapflights for your next trip

Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.

Top 2 airlines flying from Knoxville to Spartanburg

Discover the top 2 airlines that operate flights from Knoxville to Spartanburg. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated March 28, 2025.
AirlineCheapestAverageFlexibilityOn-time
DeltaCheapest$326Average$366FlexibilityNo cancel feeOn-timeN/A
American AirlinesCheapest$326Average$534FlexibilityNo cancel feeOn-time71%
100% Free
Cheapflights is completely free to use, so you can start saving the moment you arrive.
Book with Flexibility
Our users can plan ahead with confidence and find flights with no change fees
Travel Smart
Millions of people come to us for their flight needs every year. We help make travel planning easy by providing useful insights and data-driven graphs that can inform your decisions.