Spain

$512+ Cheap flights from Panama City (PTY) to Spain

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 2/18. Fares are subject to change and may not be available on all flights or dates of travel.
PTY — MAD
Jan 25 — Feb 11
We work with more than 300 partners to bring you better travel deals

Find cheap flights from Panama City to Spain with Cheapflights

1. Tell us where you want to go
Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”
2. Select your favorite providers
We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.
3. Compare prices and book
Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.

Cheap flight deals from Panama City to Spain

Discover tips and strategies to find the most affordable flight options for your journey from Panama City (PTY) to Spain (ES0). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated January 20, 2025.

Round-trip from

$661
(Gotogate)

One-way from

$512
(Vueling Global)
From Panama City Tocumen Intl to Spain
One-way flight from Panama City Tocumen Intl to Spain

Find flight deals from Panama City to Spain

Cheapest flights from Panama City to Spain
Explore the most affordable flight options available from Panama City to Spain. Find the lowest fares from popular airlines and budget airlines, with prices last updated on January 20, 2025.

This Gotogate deal was found by Cheapflights users on 1/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Gotogate is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 3/39:30 pmPTY - MAD
Nonstop9h 35mAir Europa
Wed 3/123:10 pmMAD - PTY
Nonstop10h 35mAir Europa
Deal found 1/19$661
This Avianca deal was found by Cheapflights users on 1/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 2/143:19 amPTY - MAD
1 stop13h 16mAvianca
Sat 3/110:55 amMAD - PTY
1 stop16h 05mAvianca
Deal found 1/20$678
This FlightHub deal was found by Cheapflights users on 1/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure FlightHub is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 4/118:25 pmPTY - BCN
1 stop13h 10mAir Europa
Sat 4/1911:50 amBCN - PTY
1 stop13h 50mAir Europa
Deal found 1/19$679
This Travelocity deal was found by Cheapflights users on 1/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Travelocity is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 5/195:35 pmPTY - MAD
Nonstop9h 50mIberia
Thu 6/512:00 pmMAD - PTY
Nonstop11h 05mIberia
Deal found 1/20$683
This KLM deal was found by Cheapflights users on 1/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KLM is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 2/18:50 pmPTY - MAD
1 stop14h 10mMultiple Airlines
Sat 3/155:00 pmMAD - PTY
1 stop29h 25mMultiple Airlines
Deal found 1/20$706
This Air France deal was found by Cheapflights users on 1/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Air France is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 6/38:05 pmPTY - MAD
1 stop30h 05mAir France
Mon 6/1610:05 amMAD - PTY
1 stop14h 50mAir France
Deal found 1/20$707
This KLM deal was found by Cheapflights users on 1/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KLM is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 2/56:45 pmPTY - MAD
1 stop22h 40mKLM
Mon 5/56:00 amMAD - PTY
1 stop17h 50mKLM
Deal found 1/20$708
This Air France deal was found by Cheapflights users on 1/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Air France is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 2/158:50 pmPTY - BCN
1 stop20h 05mAir France
Fri 2/286:00 amBCN - PTY
1 stop18h 50mAir France
Deal found 1/20$710
This FlightHub deal was found by Cheapflights users on 1/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure FlightHub is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 4/118:25 pmPTY - VLC
1 stop12h 50mAir Europa
Fri 4/188:35 pmVLC - PTY
1 stop29h 05mAir Europa
Deal found 1/20$711
This United Airlines deal was found by Cheapflights users on 1/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/49:45 amPTY - BCN
2 stops20h 30mUnited Airlines
Wed 10/2212:15 pmBCN - PTY
2 stops32h 35mUnited Airlines
Deal found 1/20$716
This United Airlines deal was found by Cheapflights users on 1/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 4/2810:55 pmPTY - MAD
2 stops25h 55mUnited Airlines
Mon 5/1910:50 amMAD - PTY
1 stop15h 41mUnited Airlines
Deal found 1/20$720
This KLM deal was found by Cheapflights users on 1/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KLM is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 2/118:50 pmPTY - VLC
1 stop14h 30mMultiple Airlines
Tue 2/256:00 amVLC - PTY
2 stops18h 50mMultiple Airlines
Deal found 1/20$727

Find flights from Panama City to Spain within your budget

Customize your flight search to find flights from Panama City to Spain that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated January 20, 2025.

Fly from

Any airport

Fly to

Any airport

Route

Depart

Return

Price

Panama CityMadrid

PTY - MAD

PTYMAD

Panama City Tocumen Intl

Mon 3/3

9:30 pm-1:05 pm

Nonstop9h 35m

Madrid Barajas

Wed 3/12

3:10 pm-7:45 pm

Nonstop10h 35m

$661

Panama CityMadrid

PTY - MAD

PTYMAD

Panama City Tocumen Intl

Fri 2/14

3:19 am-10:35 pm

1 stop13h 16m

Madrid Barajas

Sat 3/1

10:55 am-9:00 pm

1 stop16h 05m

$678

Panama CityBarcelona

PTY - BCN

PTYBCN

Panama City Tocumen Intl

Fri 4/11

8:25 pm-4:35 pm

1 stop13h 10m

Barcelona-El Prat

Sat 4/19

11:50 am-6:40 pm

1 stop13h 50m

$679

Panama CityMadrid

PTY - MAD

PTYMAD

Panama City Tocumen Intl

Mon 5/19

5:35 pm-10:25 am

Nonstop9h 50m

Madrid Barajas

Thu 6/5

12:00 pm-4:05 pm

Nonstop11h 05m

$683

Panama CityMadrid

PTY - MAD

PTYMAD

Panama City Tocumen Intl

Sat 2/1

8:50 pm-5:00 pm

1 stop14h 10m

Madrid Barajas

Sat 3/15

5:00 pm-4:25 pm

1 stop29h 25m

$706

Panama CityMadrid

PTY - MAD

PTYMAD

Panama City Tocumen Intl

Tue 6/3

8:05 pm-9:10 am

1 stop30h 05m

Madrid Barajas

Mon 6/16

10:05 am-5:55 pm

1 stop14h 50m

$707

Panama CityMadrid

PTY - MAD

PTYMAD

Panama City Tocumen Intl

Wed 2/5

6:45 pm-11:25 pm

1 stop22h 40m

Madrid Barajas

Mon 5/5

6:00 am-4:50 pm

1 stop17h 50m

$708

Panama CityBarcelona

PTY - BCN

PTYBCN

Panama City Tocumen Intl

Sat 2/15

8:50 pm-10:55 pm

1 stop20h 05m

Barcelona-El Prat

Fri 2/28

6:00 am-6:50 pm

1 stop18h 50m

$710

Panama CityValencia

PTY - VLC

PTYVLC

Panama City Tocumen Intl

Fri 4/11

8:25 pm-4:15 pm

1 stop12h 50m

Valencia

Fri 4/18

8:35 pm-6:40 pm

1 stop29h 05m

$711

Panama CityBarcelona

PTY - BCN

PTYBCN

Panama City Tocumen Intl

Mon 5/5

9:45 am-7:50 am

2 stops39h 05m

Barcelona-El Prat

Tue 5/27

4:00 pm-8:10 pm

1 stop35h 10m

$716

Flights are sorted by cheapest round-trip flights first.

Deals found on 1/20

Showing 1-10 of 38 results
1
2
3
4

Best time to book a flight from Panama City to Spain

Have a flexible travel schedule? Discover the best time to fly to Spain from Panama City with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Travel insights for flights from Panama City to Spain

Get recent, data-driven insights about flights from Panama City to Spain including ideal travel times, pricing trends, and more.

What is the cheapest month to book a flight from Panama City to Spain?

Currently, November is the cheapest month in which you can book a flight from Panama City to Spain (average of $543). Flying from Panama City to Spain in June is currently the most expensive (average of $1,132). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from PTY to ES?

Find hourly flight availability from Panama City to Spain. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated January 20, 2025.

Regardless of the time of day you decide to fly, the ticket price will remain around the same. Book flights from Panama City to Spain as you normally would.

Weekly flight availability from Panama City to Spain

Explore weekly flight availability from Panama City to Spain. Discover flights operating on different days of the week, giving you the flexibility to choose a travel day that best fits your plans. Compare info to find the most convenient option for your journey. Data last updated January 20, 2025.

The most flights from PTY to ES0 are scheduled on a Wednesday (14 on average). You will have fewer flight options on Monday, which is when the least amount of flights are scheduled (4 on average).

Rainfall in Spain by month

Plan your trip to Spain by taking into account the average rainfall totals by month.

In terms of precipitation, rainfall in Spain ranges from 0.8 - 3.6 inches per month. October is typically the wettest month, when rainfall can reach 3.6 in. July is typically the driest time to visit Spain when rainfall is around 0.8 in.

Temperature in Spain by month

Plan your trip to Spain by taking into account the average temperature totals by month.

If weather is an important factor for your trip to Spain, use this chart to help with planning. For those seeking warmer temperatures, August is the ideal time of year to visit, when temperatures reach an average of 75.2 F. Travelers looking to avoid the cold should look outside of January, when temperatures are typically at their lowest (around 48.2 F).

Reviews of airlines servicing Spain

Get insights into the airlines that provide service to Spain. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Spain. Reviews last updated January 20, 2025.
See what other customers who have flown with Air Europa, Avianca and Air France from Panama City to Spain have to say. Users have also rated airlines in terms of entertainment options, comfort, food, crew/service, and boarding process.
8.0
Very good
8,521 reviews

Boarding

8.2

Entertainment

7.9

Comfort

8.0

Overall

8.0

Food

7.3

Crew

8.6

Reviews

1 / 10

Delta has consistently been the best U.S. airline for my travels and this flight was no exception

8.0
Very good
8,521 reviews
8.0
Very good
8,521 reviews

Boarding

8.2

Entertainment

7.9

Comfort

8.0

Overall

8.0

Food

7.3

Crew

8.6

Reviews

1 / 10

Delta has consistently been the best U.S. airline for my travels and this flight was no exception

7.8
Good
1,341 reviews
8.0
Very good
8,521 reviews

Boarding

8.2

Entertainment

7.9

Comfort

8.0

Overall

8.0

Food

7.3

Crew

8.6

Reviews

1 / 10

Delta has consistently been the best U.S. airline for my travels and this flight was no exception

7.4
Good
1,490 reviews
8.0
Very good
8,521 reviews

Boarding

8.2

Entertainment

7.9

Comfort

8.0

Overall

8.0

Food

7.3

Crew

8.6

Reviews

1 / 10

Delta has consistently been the best U.S. airline for my travels and this flight was no exception

7.4
Good
8,982 reviews
8.0
Very good
8,521 reviews

Boarding

8.2

Entertainment

7.9

Comfort

8.0

Overall

8.0

Food

7.3

Crew

8.6

Reviews

1 / 10

Delta has consistently been the best U.S. airline for my travels and this flight was no exception

7.3
Good
3,931 reviews
8.0
Very good
8,521 reviews

Boarding

8.2

Entertainment

7.9

Comfort

8.0

Overall

8.0

Food

7.3

Crew

8.6

Reviews

1 / 10

Delta has consistently been the best U.S. airline for my travels and this flight was no exception

Related info for your journey

Find useful and relevant information for your journey from Panama City to Spain. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
  • What airport do you fly from for flights from Panama City to Spain?

    Located just 11.4 mi from the city center, Panama City Tocumen Intl (PTY) is the airport most travelers will use when flying to Spain from Panama City.

  • How popular is this Panama City to Spain flight route?

  • What are the cheapest airlines to fly from Panama City to Spain one-way?

    To fly one-way, consider booking your trip with Avianca, which is currently one of the cheapest options available, starting at $524. Turkish Airlines flights start at $551 while deals on Air Europa start at $667 one-way.

  • What are the most popular routes from Panama City to Spain?

  • What are the most reliable airlines from Panama City to Spain?

    Consider Air Europa (81%), Etihad Airways (77%) or Copa Airlines (63%) when booking your flight. These represent the most reliable airlines when flying from Panama City to Spain.

  • What are the cheapest flights from Panama City to Spain?

    On average you can expect to pay $1,114 for a flight from Panama City to Spain. The cheapest flight overall is $478 while the most popular route, (Panama City Tocumen Intl - Madrid Barajas) is currently priced at $664.

  • Can I find deals for flights from Panama City to Spain that include hotel bookings?

    Yes. In addition to deals on Panama City to Spain flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Panama City to Spain?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Panama City to Spain.

  • Can I find deals for business class flights from Panama City to Spain?

    Yes. Cheapflights offers flight deals from Panama City to Spain by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Panama City to Spain?

    Currently, November is the cheapest month in which you can book a flight from Panama City to Spain (average of $543). Flying from Panama City to Spain in June is currently the most expensive (average of $1,132). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Browse thousands of different options on Cheapflights for your next trip

Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.

Top 7 airlines flying from Panama City to Spain

Discover the top 7 airlines that operate flights from Panama City to Spain. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated January 20, 2025.
AirlineCheapestAverageFlexibilityOn-time
AviancaCheapest$543Average$770FlexibilityNo cancel feeOn-time71%
Air EuropaCheapest$589Average$821FlexibilityNo cancel feeOn-time83%
United AirlinesCheapest$601Average$772FlexibilityNo cancel feeOn-time69%
IberiaCheapest$629Average$851FlexibilityNo cancel feeOn-time77%
KLMCheapest$633Average$875FlexibilityNo cancel feeOn-time75%
Air FranceCheapest$666Average$812FlexibilityNo cancel feeOn-time77%
Turkish AirlinesCheapest$728Average$776FlexibilityNo cancel feeOn-time77%
100% Free
Cheapflights is completely free to use, so you can start saving the moment you arrive.
Book with Flexibility
Our users can plan ahead with confidence and find flights with no change fees
Travel Smart
Millions of people come to us for their flight needs every year. We help make travel planning easy by providing useful insights and data-driven graphs that can inform your decisions.