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$521+ Cheap flights from Panama City (PTY) to Spain

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 5/17. Fares are subject to change and may not be available on all flights or dates of travel.
PTY — MAD
Mar 30 — Apr 61
Sun 3/30
Sun 4/6
1 adult, Economy
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Cheap flight deals from Panama City to Spain

Keep the following information in mind while searching for Panama City to Spain flight deals. Data was last updated March 25, 2025.

Round-trip from

$691
(KLM)

One-way from

$521
(SmartFares)

Popular in

July

Cheapest in

October

Average price

$745

Good round-trip deal

$727 or less

Good one-way deal

$521 or less
From Panama City Tocumen Intl to Spain
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One-way flight from Panama City Tocumen Intl to Spain
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Highest demand for flights based on searches. 6% potential increase in price ($52 potential increase over avg. RT price).
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Cheapest flight prices on average. 1% potential price decrease ($10 potential savings vs. average RT price).
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Average for round-trip flights in March 2025
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Price to beat on a round-trip flight from Panama City Tocumen Intl to Spain.
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Price to beat on a one-way flight from Panama City Tocumen Intl to Spain.
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Find flight deals from Panama City to Spain

Cheapest flights from Panama City to Spain
Explore the most affordable flight options available from Panama City to Spain. Find the lowest fares from popular airlines and budget airlines, with prices last updated on March 25, 2025.

This KLM deal was found by Cheapflights users on 3/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KLM is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 5/197:55 pmPTY - MAD
1 stop13h 50mMultiple Airlines
Mon 6/21:05 pmMAD - PTY
1 stop34h 45mMultiple Airlines
Deal found 3/24$691
This KLM deal was found by Cheapflights users on 3/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KLM is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/246:50 pmPTY - MAD
1 stop21h 35mKLM
Sat 6/75:10 pmMAD - PTY
1 stop30h 40mKLM
Deal found 3/24$694
This Gotogate deal was found by Cheapflights users on 3/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Gotogate is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 5/268:25 pmPTY - MAD
Nonstop9h 50mAir Europa
Sun 6/83:05 pmMAD - PTY
Nonstop10h 35mAir Europa
Deal found 3/24$704
This Air France deal was found by Cheapflights users on 3/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Air France is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 5/188:00 amPTY - MAD
1 stop18h 35mAir France
Tue 5/276:00 amMAD - PTY
1 stop18h 45mAir France
Deal found 3/23$711
This Iberia deal was found by Cheapflights users on 3/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Iberia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 5/125:35 pmPTY - BCN
1 stop22h 15mIberia
Sat 5/317:00 amBCN - PTY
1 stop16h 05mIberia
Deal found 3/24$727
This Air Europa deal was found by Cheapflights users on 3/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Air Europa is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 5/118:25 pmPTY - VLC
1 stop12h 50mAir Europa
Sat 5/1712:35 pmVLC - PTY
1 stop13h 05mAir Europa
Deal found 3/24$736
This Air Europa deal was found by Cheapflights users on 3/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Air Europa is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/248:25 pmPTY - AGP
1 stop12h 50mAir Europa
Wed 6/48:35 amAGP - PTY
1 stop17h 05mAir Europa
Deal found 3/24$737
This KLM deal was found by Cheapflights users on 3/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KLM is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 6/86:50 pmPTY - AGP
1 stop31h 55mKLM
Wed 6/1810:40 amAGP - PTY
1 stop37h 10mKLM
Deal found 3/24$744
This KLM deal was found by Cheapflights users on 3/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KLM is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 6/76:50 pmPTY - AGP
1 stop31h 55mMultiple Airlines
Tue 6/175:55 amAGP - PTY
1 stop18h 50mMultiple Airlines
Deal found 3/24$745
This FlightHub deal was found by Cheapflights users on 3/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure FlightHub is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/248:25 pmPTY - BCN
1 stop13h 10mAir Europa
Sat 6/1411:50 amBCN - PTY
1 stop13h 50mAir Europa
Deal found 3/24$748
This Air France deal was found by Cheapflights users on 3/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Air France is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 5/187:55 pmPTY - BCN
1 stop19h 45mAir France
Sat 5/316:10 amBCN - PTY
1 stop18h 35mAir France
Deal found 3/25$755
This KLM deal was found by Cheapflights users on 3/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KLM is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 6/97:55 pmPTY - BCN
1 stop14h 15mMultiple Airlines
Wed 6/185:20 pmBCN - PTY
1 stop30h 30mMultiple Airlines
Deal found 3/24$761

Cheapflights Fare Finder

Customize your flight search to find flights from Panama City to Spain that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated March 25, 2025.
Use the filters below to find and compare flights from Panama City to Spain that are best for you.

Fly from

Panama City

Fly to

Spain

Route

Depart

Return

Price

Panama CityMadrid

PTY - MAD

PTYMAD

Panama City Tocumen Intl

Mon 5/19

7:55 pm-4:45 pm

1 stop13h 50m

Madrid Barajas

Mon 6/2

1:05 pm-4:50 pm

1 stop34h 45m

$691

Panama CityMadrid

PTY - MAD

PTYMAD

Panama City Tocumen Intl

Sat 5/24

6:50 pm-11:25 pm

1 stop21h 35m

Madrid Barajas

Sat 6/7

5:10 pm-4:50 pm

1 stop30h 40m

$694

Panama CityMadrid

PTY - MAD

PTYMAD

Panama City Tocumen Intl

Mon 5/26

8:25 pm-1:15 pm

Nonstop9h 50m

Madrid Barajas

Sun 6/8

3:05 pm-6:40 pm

Nonstop10h 35m

$704

Panama CityMadrid

PTY - MAD

PTYMAD

Panama City Tocumen Intl

Sun 5/18

8:00 am-9:35 am

1 stop18h 35m

Madrid Barajas

Tue 5/27

6:00 am-5:45 pm

1 stop18h 45m

$711

Panama CityBarcelona

PTY - BCN

PTYBCN

Panama City Tocumen Intl

Mon 5/12

5:35 pm-10:50 pm

1 stop22h 15m

Barcelona-El Prat

Sat 5/31

7:00 am-4:05 pm

1 stop16h 05m

$727

Panama CityValencia

PTY - VLC

PTYVLC

Panama City Tocumen Intl

Sun 5/11

8:25 pm-4:15 pm

1 stop12h 50m

Valencia

Sat 5/17

12:35 pm-6:40 pm

1 stop13h 05m

$736

Panama CityMálaga

PTY - AGP

PTYAGP

Panama City Tocumen Intl

Sat 5/24

8:25 pm-4:15 pm

1 stop12h 50m

Malaga

Wed 6/4

8:35 am-6:40 pm

1 stop17h 05m

$737

Panama CityMálaga

PTY - AGP

PTYAGP

Panama City Tocumen Intl

Sun 6/8

6:50 pm-9:45 am

1 stop31h 55m

Malaga

Wed 6/18

10:40 am-4:50 pm

1 stop37h 10m

$744

Panama CityMálaga

PTY - AGP

PTYAGP

Panama City Tocumen Intl

Sat 6/7

6:50 pm-9:45 am

1 stop31h 55m

Malaga

Tue 6/17

5:55 am-5:45 pm

1 stop18h 50m

$745

Panama CityBarcelona

PTY - BCN

PTYBCN

Panama City Tocumen Intl

Sat 5/24

8:25 pm-4:35 pm

1 stop13h 10m

Barcelona-El Prat

Sat 6/14

11:50 am-6:40 pm

1 stop13h 50m

$748

Flights are sorted by cheapest round-trip flights first.

Deals found on 3/24

Showing 1-10 of 40 results
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Best time to book a flight from Panama City to Spain

Have a flexible travel schedule? Discover the best time to fly to Spain from Panama City with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Panama City to Spain

What is the cheapest month to book a flight from Panama City to Spain?

Currently, November is the cheapest month in which you can book a flight from Panama City to Spain (average of $543). Flying from Panama City to Spain in June is currently the most expensive (average of $1,112). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from PTY to ES?

Find hourly flight availability from Panama City to Spain. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated March 25, 2025.

Regardless of the time of day you decide to fly, the ticket price will remain around the same. Book flights from Panama City to Spain as you normally would.

Rainfall in Spain by month

Plan your trip to Spain by taking into account the average rainfall totals by month.

In terms of precipitation, rainfall in Spain ranges from 0.8 - 3.6 inches per month. October is typically the wettest month, when rainfall can reach 3.6 in. July is typically the driest time to visit Spain when rainfall is around 0.8 in.

Temperature in Spain by month

Plan your trip to Spain by taking into account the average temperature totals by month.

If weather is an important factor for your trip to Spain, use this chart to help with planning. For those seeking warmer temperatures, August is the ideal time of year to visit, when temperatures reach an average of 75.2 F. Travelers looking to avoid the cold should look outside of January, when temperatures are typically at their lowest (around 48.2 F).

Reviews of airlines servicing Spain

Get insights into the airlines that provide service to Spain. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Spain. Reviews last updated March 25, 2025.
See what other customers who have flown with KLM, Air France and United Airlines from Panama City to Spain have to say. Users have also rated airlines in terms of entertainment options, comfort, food, crew/service, and boarding process.
KLM
7.8
Good
1,318 reviews

Boarding

7.8

Overall

7.8

Crew

8.4

Food

7.3

Comfort

7.7

Entertainment

7.1

Reviews

1 / 20
8.0
Excellent

Anonymous,Mar 2025

LBA - AMS

Overall, the flight from Leeds Bradford to Amsterdam was at expected. The crew were efficient at boarding and professional on board. The only issue was extremely slow check in at Leeds Bradford which was very frustrating.
KLM
7.8
Good
1,318 reviews
KLM
7.8
Good
1,318 reviews

Boarding

7.8

Overall

7.8

Crew

8.4

Food

7.3

Comfort

7.7

Entertainment

7.1

Reviews

1 / 20
8.0
Excellent

Anonymous,Mar 2025

LBA - AMS

Overall, the flight from Leeds Bradford to Amsterdam was at expected. The crew were efficient at boarding and professional on board. The only issue was extremely slow check in at Leeds Bradford which was very frustrating.
Air France
7.4
Good
1,422 reviews
KLM
7.8
Good
1,318 reviews

Boarding

7.8

Overall

7.8

Crew

8.4

Food

7.3

Comfort

7.7

Entertainment

7.1

Reviews

1 / 20
8.0
Excellent

Anonymous,Mar 2025

LBA - AMS

Overall, the flight from Leeds Bradford to Amsterdam was at expected. The crew were efficient at boarding and professional on board. The only issue was extremely slow check in at Leeds Bradford which was very frustrating.
United Airlines
7.4
Good
8,605 reviews
KLM
7.8
Good
1,318 reviews

Boarding

7.8

Overall

7.8

Crew

8.4

Food

7.3

Comfort

7.7

Entertainment

7.1

Reviews

1 / 20
8.0
Excellent

Anonymous,Mar 2025

LBA - AMS

Overall, the flight from Leeds Bradford to Amsterdam was at expected. The crew were efficient at boarding and professional on board. The only issue was extremely slow check in at Leeds Bradford which was very frustrating.
Turkish Airlines
7.3
Good
3,745 reviews
KLM
7.8
Good
1,318 reviews

Boarding

7.8

Overall

7.8

Crew

8.4

Food

7.3

Comfort

7.7

Entertainment

7.1

Reviews

1 / 20
8.0
Excellent

Anonymous,Mar 2025

LBA - AMS

Overall, the flight from Leeds Bradford to Amsterdam was at expected. The crew were efficient at boarding and professional on board. The only issue was extremely slow check in at Leeds Bradford which was very frustrating.
Air Europa
6.9
Okay
504 reviews
KLM
7.8
Good
1,318 reviews

Boarding

7.8

Overall

7.8

Crew

8.4

Food

7.3

Comfort

7.7

Entertainment

7.1

Reviews

1 / 20
8.0
Excellent

Anonymous,Mar 2025

LBA - AMS

Overall, the flight from Leeds Bradford to Amsterdam was at expected. The crew were efficient at boarding and professional on board. The only issue was extremely slow check in at Leeds Bradford which was very frustrating.

Related info for your journey

Find useful and relevant information for your journey from Panama City to Spain. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly from for flights from Panama City to Spain?

    Located just 11.4 mi from the city center, Panama City Tocumen Intl (PTY) is the airport most travelers will use when flying to Spain from Panama City.

  • How popular is this Panama City to Spain flight route?

    The Panama City Tocumen Intl to Spain flight path was viewed by 17 users in the past month. Keep an eye out for changes in search interest prior to high and low season.

  • What are the cheapest airlines to fly from Panama City to Spain one-way?

    To fly one-way, consider booking your trip with Air Europa, which is currently one of the cheapest options available, starting at $521. Avianca flights start at $536 while deals on Turkish Airlines start at $551 one-way.

  • What are the most popular routes from Panama City to Spain?

    Most travelers choose Panama City Tocumen Intl - Madrid Barajas, Panama City Tocumen Intl - Barcelona-El Prat or Panama City Tocumen Intl - Ibiza when deciding on the best route from Panama City to Spain.

  • What are the most reliable airlines from Panama City to Spain?

    Consider Air Europa (90%), Etihad Airways (90%) or China Eastern (90%) when booking your flight. These represent the most reliable airlines when flying from Panama City to Spain.

  • What are the cheapest flights from Panama City to Spain?

    On average you can expect to pay $1,599 for a flight from Panama City to Spain. The cheapest flight overall is $422 while the most popular route, (Panama City Tocumen Intl - Madrid Barajas) is currently priced at $694.

  • Can I find deals for flights from Panama City to Spain that include hotel bookings?

    Yes. In addition to deals on Panama City to Spain flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Panama City to Spain?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Panama City to Spain.

  • Can I find deals for business class flights from Panama City to Spain?

    Yes. Cheapflights offers flight deals from Panama City to Spain by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Panama City to Spain?

    Currently, November is the cheapest month in which you can book a flight from Panama City to Spain (average of $543). Flying from Panama City to Spain in June is currently the most expensive (average of $1,112). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

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Alternative routes for Panama City to Spain

See prices for flight routes from nearby airports that may be better suited for you.
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Top 7 airlines flying from Panama City to Spain

Discover the top 7 airlines that operate flights from Panama City to Spain. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated March 25, 2025.
AirlineCheapestAverageFlexibilityOn-time
AviancaCheapest$543Average$788FlexibilityNo cancel feeOn-time71%
Air EuropaCheapest$589Average$807FlexibilityNo cancel feeOn-time83%
IberiaCheapest$633Average$891FlexibilityNo cancel feeOn-time77%
Air FranceCheapest$666Average$814FlexibilityNo cancel feeOn-time77%
KLMCheapest$670Average$873FlexibilityNo cancel feeOn-time75%
United AirlinesCheapest$678Average$795FlexibilityNo cancel feeOn-time69%
Turkish AirlinesCheapest$728Average$798FlexibilityNo cancel feeOn-time77%
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