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$438+ Cheap flights from Missouri to Spain

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 4/1. Fares are subject to change and may not be available on all flights or dates of travel.
STL — MAD
Feb 25 — Mar 41
Tue 2/25
Tue 3/4
1 adult, Economy
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Cheap flight deals from Missouri to Spain

Keep the following information in mind while searching for Missouri to Spain flight deals. Data was last updated February 20, 2025.

Round-trip from

$673
(Justfly.com)

One-way from

$438
(Kiwi.com)
From Missouri to Spain
Search Deals
One-way flight from Missouri to Spain
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Find flight deals from Missouri to Spain

Cheapest flights from Missouri to Spain
Explore the most affordable flight options available from Missouri to Spain. Find the lowest fares from popular airlines and budget airlines, with prices last updated on February 20, 2025.

This United Airlines deal was found by Cheapflights users on 2/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/116:15 amSTL - MAD
2 stops20h 20mUnited Airlines
Fri 1/912:15 pmMAD - STL
2 stops35h 59mUnited Airlines
Deal found 2/20$651
This Finnair deal was found by Cheapflights users on 2/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Finnair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/112:44 pmSTL - MAD
1 stop12h 11mMultiple Airlines
Fri 1/91:15 pmMAD - STL
1 stop14h 08mMultiple Airlines
Deal found 2/20$664
This oojo deal was found by Cheapflights users on 2/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure oojo is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 4/111:55 amSTL - MAD
1 stop18h 30mBritish Airways
Tue 4/81:45 pmMAD - STL
1 stop14h 13mBritish Airways
Deal found 2/19$673
This StudentUniverse deal was found by Cheapflights users on 2/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure StudentUniverse is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 4/16:29 pmSTL - MAD
1 stop11h 56mFinnair
Tue 4/86:45 amMAD - STL
2 stops22h 27mFinnair
Deal found 2/19$674
This American Airlines deal was found by Cheapflights users on 2/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/111:55 pmSTL - MAD
1 stop12h 30mAmerican Airlines
Fri 1/912:40 pmMAD - STL
2 stops16h 09mAmerican Airlines
Deal found 2/20$679
This Cheapflightsfares deal was found by Cheapflights users on 2/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/1312:54 pmSTL - MAD
1 stop12h 01mIberia
Sat 1/1011:35 amMAD - STL
1 stop17h 14mIberia
Deal found 2/20$695
This lol.travel deal was found by Cheapflights users on 2/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure lol.travel is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 3/2310:24 amMCI - MAD
1 stop17h 01mIberia
Tue 4/81:45 pmMAD - MCI
1 stop14h 40mIberia
Deal found 2/20$696
This Expedia deal was found by Cheapflights users on 2/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/29:20 amSTL - BCN
2 stops15h 40mIberia
Mon 12/89:05 pmBCN - STL
2 stops42h 38mIberia
Deal found 2/20$701
This Flighttix deal was found by Cheapflights users on 2/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Flighttix is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 3/234:27 pmMCI - MAD
2 stops32h 33mVirgin Atlantic
Tue 4/812:40 pmMAD - MCI
2 stops34h 43mVirgin Atlantic
Deal found 2/20$701
This United Airlines deal was found by Cheapflights users on 2/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 3/198:00 amMCI - MAD
2 stops26h 45mUnited Airlines
Wed 3/2612:15 pmMAD - MCI
2 stops39h 44mUnited Airlines
Deal found 2/19$726
This Expedia deal was found by Cheapflights users on 2/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 3/2012:01 pmSGF - MAD
2 stops24h 29mBritish Airways
Thu 3/273:55 pmMAD - SGF
1 stop36h 32mBritish Airways
Deal found 2/20$732
This Air France deal was found by Cheapflights users on 2/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Air France is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 3/195:37 pmMCI - MAD
2 stops15h 48mMultiple Airlines
Wed 3/2610:00 amMAD - MCI
1 stop17h 44mMultiple Airlines
Deal found 2/19$740

Find flights from Missouri to Spain within your budget

Customize your flight search to find flights from Missouri to Spain that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated February 20, 2025.

Fly from

Missouri

Fly to

Spain

Route

Depart

Return

Price

St. LouisMadrid

STL - MAD

STLMAD

Lambert-St Louis

Tue 4/1

11:55 am-1:25 pm

1 stop18h 30m

Madrid Barajas

Tue 4/8

1:45 pm-8:58 pm

1 stop14h 13m

$673

St. LouisMadrid

STL - MAD

STLMAD

Lambert-St Louis

Tue 4/1

6:29 pm-1:25 pm

1 stop11h 56m

Madrid Barajas

Tue 4/8

6:45 am-10:12 pm

2 stops22h 27m

$674

St. LouisMadrid

STL - MAD

STLMAD

Lambert-St Louis

Tue 4/1

6:30 am-6:40 am

2 stops17h 10m

Madrid Barajas

Tue 4/8

12:45 pm-12:20 pm

2 stops30h 35m

$680

Kansas CityMadrid

MCI - MAD

MCIMAD

Kansas City

Sun 3/23

10:24 am-9:25 am

1 stop17h 01m

Madrid Barajas

Tue 4/8

1:45 pm-9:25 pm

1 stop14h 40m

$696

Kansas CityMadrid

MCI - MAD

MCIMAD

Kansas City

Sun 3/23

4:27 pm-7:00 am

2 stops32h 33m

Madrid Barajas

Tue 4/8

12:40 pm-4:23 pm

2 stops34h 43m

$701

St. LouisMadrid

STL - MAD

STLMAD

Lambert-St Louis

Sat 3/29

9:28 am-8:25 am

1 stop16h 57m

Madrid Barajas

Tue 4/8

1:45 pm-8:58 pm

1 stop14h 13m

$702

Kansas CityMadrid

MCI - MAD

MCIMAD

Kansas City

Wed 3/19

8:00 am-4:45 pm

2 stops26h 45m

Madrid Barajas

Wed 3/26

12:15 pm-9:59 pm

2 stops39h 44m

$726

SpringfieldMadrid

SGF - MAD

SGFMAD

Springfield-Branson

Thu 3/20

12:01 pm-6:30 pm

2 stops24h 29m

Madrid Barajas

Thu 3/27

3:55 pm-10:27 pm

1 stop36h 32m

$732

St. LouisMadrid

STL - MAD

STLMAD

Lambert-St Louis

Tue 3/18

8:49 am-5:45 am

1 stop14h 56m

Madrid Barajas

Tue 3/25

10:45 am-10:18 pm

2 stops17h 33m

$739

Kansas CityMadrid

MCI - MAD

MCIMAD

Kansas City

Wed 3/19

5:37 pm-3:25 pm

2 stops15h 48m

Madrid Barajas

Wed 3/26

10:00 am-9:44 pm

1 stop17h 44m

$740

Flights are sorted by cheapest round-trip flights first.

Deals found on 2/20

Showing 1-10 of 60 results
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Best time to book a flight from Missouri to Spain

Have a flexible travel schedule? Discover the best time to fly to Spain from Missouri with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Travel insights for flights from Missouri to Spain

Get recent, data-driven insights about flights from Missouri to Spain including ideal travel times, pricing trends, and more.

What is the cheapest month to book a flight from Missouri to Spain?

Currently, November is the cheapest month in which you can book a flight from Missouri to Spain (average of $543). Flying from Missouri to Spain in June is currently the most expensive (average of $1,124). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from MO to ES?

Find hourly flight availability from Missouri to Spain. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated February 20, 2025.

Regardless of the time of day you decide to fly, the ticket price will remain around the same. Book flights from Missouri to Spain as you normally would.

Rainfall in Spain by month

Plan your trip to Spain by taking into account the average rainfall totals by month.

In terms of precipitation, rainfall in Spain ranges from 0.8 - 3.6 inches per month. October is typically the wettest month, when rainfall can reach 3.6 in. July is typically the driest time to visit Spain when rainfall is around 0.8 in.

Temperature in Spain by month

Plan your trip to Spain by taking into account the average temperature totals by month.

If weather is an important factor for your trip to Spain, use this chart to help with planning. For those seeking warmer temperatures, August is the ideal time of year to visit, when temperatures reach an average of 75.2 F. Travelers looking to avoid the cold should look outside of January, when temperatures are typically at their lowest (around 48.2 F).

Reviews of airlines servicing Spain

Get insights into the airlines that provide service to Spain. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Spain. Reviews last updated February 20, 2025.
Peruse reviews from past customers who have flown with Delta, KLM and Finnair from Missouri to Spain to help guide your decision. You can also see how each airline compares in terms of entertainment options, comfort, food, crew/service, and boarding process.
Delta
8.0
Very good
8,219 reviews

Entertainment

7.9

Boarding

8.2

Overall

8.0

Comfort

8.0

Food

7.3

Crew

8.5

Reviews

1 / 20

10.0
Excellent

Aaron,Oct 2024

LAX - LHR

This was a flight operated by Virgin Atlantic in their Upper Class cabin. Overall, an outstanding experience.

Delta
8.0
Very good
8,219 reviews
Delta
8.0
Very good
8,219 reviews

Entertainment

7.9

Boarding

8.2

Overall

8.0

Comfort

8.0

Food

7.3

Crew

8.5

Reviews

1 / 20

10.0
Excellent

Aaron,Oct 2024

LAX - LHR

This was a flight operated by Virgin Atlantic in their Upper Class cabin. Overall, an outstanding experience.

KLM
7.8
Good
1,333 reviews
Delta
8.0
Very good
8,219 reviews

Entertainment

7.9

Boarding

8.2

Overall

8.0

Comfort

8.0

Food

7.3

Crew

8.5

Reviews

1 / 20

10.0
Excellent

Aaron,Oct 2024

LAX - LHR

This was a flight operated by Virgin Atlantic in their Upper Class cabin. Overall, an outstanding experience.

Finnair
7.6
Good
1,274 reviews
Delta
8.0
Very good
8,219 reviews

Entertainment

7.9

Boarding

8.2

Overall

8.0

Comfort

8.0

Food

7.3

Crew

8.5

Reviews

1 / 20

10.0
Excellent

Aaron,Oct 2024

LAX - LHR

This was a flight operated by Virgin Atlantic in their Upper Class cabin. Overall, an outstanding experience.

SWISS
7.5
Good
1,568 reviews
Delta
8.0
Very good
8,219 reviews

Entertainment

7.9

Boarding

8.2

Overall

8.0

Comfort

8.0

Food

7.3

Crew

8.5

Reviews

1 / 20

10.0
Excellent

Aaron,Oct 2024

LAX - LHR

This was a flight operated by Virgin Atlantic in their Upper Class cabin. Overall, an outstanding experience.

Virgin Atlantic
7.5
Good
654 reviews
Delta
8.0
Very good
8,219 reviews

Entertainment

7.9

Boarding

8.2

Overall

8.0

Comfort

8.0

Food

7.3

Crew

8.5

Reviews

1 / 20

10.0
Excellent

Aaron,Oct 2024

LAX - LHR

This was a flight operated by Virgin Atlantic in their Upper Class cabin. Overall, an outstanding experience.

Related info for your journey

Find useful and relevant information for your journey from Missouri to Spain. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What are the cheapest airlines to fly from Missouri to Spain one-way?

    The cheapest airline one-way is British Airways, with whom users have recently found tickets for as low as $536. However, be on the lookout for offers from American Airlines and United Airlines, as they are both options that can get you from Missouri to Spain for a low price.

  • Can I find deals for flights from Missouri to Spain that include hotel bookings?

    Yes. In addition to deals on Missouri to Spain flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Missouri to Spain?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Missouri to Spain.

  • Can I find deals for business class flights from Missouri to Spain?

    Yes. Cheapflights offers flight deals from Missouri to Spain by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Missouri to Spain?

    Currently, November is the cheapest month in which you can book a flight from Missouri to Spain (average of $543). Flying from Missouri to Spain in June is currently the most expensive (average of $1,124). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

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Alternative routes for Missouri to Spain

See prices for flight routes from nearby airports that may be better suited for you.
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Top 9 airlines flying from Missouri to Spain

Discover the top 9 airlines that operate flights from Missouri to Spain. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated February 20, 2025.
AirlineCheapestAverageFlexibilityOn-time
KLMCheapest$490Average$995FlexibilityNo cancel feeOn-time75%
LufthansaCheapest$530Average$1,012FlexibilityNo cancel feeOn-time76%
United AirlinesCheapest$542Average$1,066FlexibilityNo cancel feeOn-time69%
British AirwaysCheapest$545Average$953FlexibilityNo cancel feeOn-time70%
IberiaCheapest$550Average$1,001FlexibilityNo cancel feeOn-time77%
DeltaCheapest$556Average$1,121FlexibilityNo cancel feeOn-timeN/A
American AirlinesCheapest$564Average$1,077FlexibilityNo cancel feeOn-time71%
Air FranceCheapest$650Average$1,069FlexibilityNo cancel feeOn-time77%
Air CanadaCheapest$670Average$1,177FlexibilityNo cancel feeOn-time67%
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