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$325+ Cheap flights from Missouri to Spain

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 9/29. Fares are subject to change and may not be available on all flights or dates of travel.
STL — MAD
Apr 22 — Apr 291
Tue 4/22
Tue 4/29
1 adult, Economy
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Cheap flight deals from Missouri to Spain

Keep the following information in mind while searching for Missouri to Spain flight deals. Data was last updated April 17, 2025.

Round-trip from

$606
(CheapOair)

One-way from

$325
(Kiwi.com)

Popular in

May

Cheapest in

February

Average price

$936
From Missouri to Spain
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One-way flight from Missouri to Spain
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Highest demand for flights based on searches. 21% potential increase in price ($270 potential increase over avg. RT price).
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Cheapest flight prices on average. 4% potential price decrease ($40 potential savings vs. average RT price).
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Average for round-trip flights in April 2025
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Find flight deals from Missouri to Spain

Cheapest flights from Missouri to Spain
Explore the most affordable flight options available from Missouri to Spain. Find the lowest fares from popular airlines and budget airlines, with prices last updated on April 17, 2025.

This Delta deal was found by Cheapflights users on 4/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/176:00 amSTL - BCN
1 stop17h 00mDelta
Fri 10/39:00 amBCN - STL
1 stop18h 50mDelta
Deal found 4/15$572
This Air Canada deal was found by Cheapflights users on 4/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Air Canada is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/191:30 pmSTL - BCN
1 stop11h 20mAir Canada
Wed 10/112:15 pmBCN - STL
2 stops34h 23mAir Canada
Deal found 4/15$595
This Expedia deal was found by Cheapflights users on 4/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/164:05 pmSTL - BCN
2 stops45h 25mMultiple Airlines
Tue 9/301:15 pmBCN - STL
1 stop13h 18mMultiple Airlines
Deal found 4/15$597
This United Airlines deal was found by Cheapflights users on 4/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/195:18 pmSTL - BCN
1 stop12h 47mUnited Airlines
Wed 11/2612:15 pmBCN - STL
2 stops31h 05mUnited Airlines
Deal found 4/16$599
This United Airlines deal was found by Cheapflights users on 4/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/106:37 pmMCI - BCN
1 stop11h 28mUnited Airlines
Tue 11/1812:15 pmBCN - MCI
3 stops34h 48mUnited Airlines
Deal found 4/17$599
This Expedia deal was found by Cheapflights users on 4/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/167:59 pmSTL - BCN
2 stops43h 46mBritish Airways
Tue 9/3010:15 amBCN - STL
2 stops17h 06mBritish Airways
Deal found 4/15$605
This CheapOair deal was found by Cheapflights users on 4/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/17:30 amMCI - BCN
2 stops17h 20mAir Canada
Wed 10/81:15 pmBCN - MCI
2 stops32h 05mAir Canada
Deal found 4/16$606
This Finnair deal was found by Cheapflights users on 4/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Finnair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/105:09 amMCI - BCN
1 stop20h 31mMultiple Airlines
Tue 11/181:30 pmBCN - MCI
1 stop14h 15mMultiple Airlines
Deal found 4/17$612
This Gurufare deal was found by Cheapflights users on 4/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Gurufare is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/193:45 pmSTL - BCN
1 stop13h 30mLufthansa
Wed 11/266:50 amBCN - STL
1 stop14h 05mLufthansa
Deal found 4/16$618
This Iberia deal was found by Cheapflights users on 4/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Iberia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/1712:07 pmSTL - BCN
1 stop15h 03mIberia
Thu 10/210:45 amBCN - STL
1 stop15h 23mIberia
Deal found 4/16$621
This Orbitz deal was found by Cheapflights users on 4/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Orbitz is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/178:07 pmMCI - BCN
2 stops19h 38mBritish Airways
Tue 9/3010:45 amBCN - MCI
1 stop16h 51mBritish Airways
Deal found 4/17$626
This FlightHub deal was found by Cheapflights users on 4/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure FlightHub is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 10/53:30 pmSTL - BIO
1 stop19h 55mLufthansa
Wed 10/156:45 amBIO - STL
1 stop13h 45mLufthansa
Deal found 4/17$645

Cheapflights Fare Finder

Customize your flight search to find flights from Missouri to Spain that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated April 17, 2025.
Use the filters below to find and compare flights from Missouri to Spain that are best for you.

Fly from

Missouri

Fly to

Spain

Route

Depart

Return

Price

St. LouisBarcelona

STL - BCN

STLBCN

Lambert-St Louis

Wed 9/17

6:00 am-6:00 am

1 stop17h 00m

Barcelona-El Prat

Fri 10/3

9:00 am-8:50 pm

1 stop18h 50m

$572

St. LouisBarcelona

STL - BCN

STLBCN

Lambert-St Louis

Fri 9/19

1:30 pm-7:50 am

1 stop11h 20m

Barcelona-El Prat

Wed 10/1

12:15 pm-3:38 pm

2 stops34h 23m

$595

St. LouisBarcelona

STL - BCN

STLBCN

Lambert-St Louis

Tue 9/16

4:05 pm-8:30 pm

2 stops45h 25m

Barcelona-El Prat

Tue 9/30

1:15 pm-7:33 pm

1 stop13h 18m

$597

St. LouisBarcelona

STL - BCN

STLBCN

Lambert-St Louis

Tue 9/16

7:59 pm-10:45 pm

2 stops43h 46m

Barcelona-El Prat

Tue 9/30

10:15 am-8:21 pm

2 stops17h 06m

$605

Kansas CityBarcelona

MCI - BCN

MCIBCN

Kansas City

Wed 10/1

7:30 am-7:50 am

2 stops17h 20m

Barcelona-El Prat

Wed 10/8

1:15 pm-2:20 pm

2 stops32h 05m

$606

St. LouisBarcelona

STL - BCN

STLBCN

Lambert-St Louis

Wed 9/17

12:07 pm-10:10 am

1 stop15h 03m

Barcelona-El Prat

Thu 10/2

10:45 am-7:08 pm

1 stop15h 23m

$621

Kansas CityBarcelona

MCI - BCN

MCIBCN

Kansas City

Wed 10/1

9:59 am-6:00 am

1 stop13h 01m

Barcelona-El Prat

Wed 10/8

9:00 am-6:38 pm

1 stop16h 38m

$622

Kansas CityBarcelona

MCI - BCN

MCIBCN

Kansas City

Wed 9/17

8:07 pm-10:45 pm

2 stops19h 38m

Barcelona-El Prat

Tue 9/30

10:45 am-8:36 pm

1 stop16h 51m

$626

St. LouisBilbao

STL - BIO

STLBIO

Lambert-St Louis

Sun 10/5

3:30 pm-6:25 pm

1 stop19h 55m

Bilbao

Wed 10/15

6:45 am-1:30 pm

1 stop13h 45m

$645

Kansas CityMadrid

MCI - MAD

MCIMAD

Kansas City

Tue 10/14

6:08 pm-5:30 pm

2 stops16h 22m

Madrid Barajas

Mon 10/20

7:55 pm-8:15 pm

2 stops31h 20m

$647

Flights are sorted by cheapest round-trip flights first.

Deals found on 4/17

Showing 1-10 of 60 results
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Best time to book a flight from Missouri to Spain

Have a flexible travel schedule? Discover the best time to fly to Spain from Missouri with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Missouri to Spain

What is the cheapest month to book a flight from Missouri to Spain?

Currently, November is the cheapest month in which you can book a flight from Missouri to Spain (average of $543). Flying from Missouri to Spain in June is currently the most expensive (average of $1,101). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from MO to ES?

Find hourly flight availability from Missouri to Spain. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated April 17, 2025.

Regardless of the time of day you decide to fly, the ticket price will remain around the same. Book flights from Missouri to Spain as you normally would.

Rainfall in Spain by month

Plan your trip to Spain by taking into account the average rainfall totals by month.

In terms of precipitation, rainfall in Spain ranges from 0.8 - 3.6 inches per month. October is typically the wettest month, when rainfall can reach 3.6 in. July is typically the driest time to visit Spain when rainfall is around 0.8 in.

Temperature in Spain by month

Plan your trip to Spain by taking into account the average temperature totals by month.

If weather is an important factor for your trip to Spain, use this chart to help with planning. For those seeking warmer temperatures, August is the ideal time of year to visit, when temperatures reach an average of 75.2 F. Travelers looking to avoid the cold should look outside of January, when temperatures are typically at their lowest (around 48.2 F).

Reviews of airlines servicing Spain

Get insights into the airlines that provide service to Spain. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Spain. Reviews last updated April 17, 2025.
Peruse reviews from past customers who have flown with Asiana Airlines, Delta and KLM from Missouri to Spain to help guide your decision. You can also see how each airline compares in terms of entertainment options, comfort, food, crew/service, and boarding process.
Asiana Airlines
8.2
Very good
438 reviews

Food

8.0

Comfort

8.0

Entertainment

7.7

Boarding

8.3

Overall

8.2

Crew

8.5

Reviews

1 / 20
4.0
Okay

Ramón,Feb 2025

ICN - SGN

The same as my experience from NYC to Incheon, just 1 EVER LASTING LONG LINE. No group calling out anything, just telling everyone to line up.
Asiana Airlines
8.2
Very good
438 reviews
Asiana Airlines
8.2
Very good
438 reviews

Food

8.0

Comfort

8.0

Entertainment

7.7

Boarding

8.3

Overall

8.2

Crew

8.5

Reviews

1 / 20
4.0
Okay

Ramón,Feb 2025

ICN - SGN

The same as my experience from NYC to Incheon, just 1 EVER LASTING LONG LINE. No group calling out anything, just telling everyone to line up.
Delta
8.0
Very good
7,916 reviews
Asiana Airlines
8.2
Very good
438 reviews

Food

8.0

Comfort

8.0

Entertainment

7.7

Boarding

8.3

Overall

8.2

Crew

8.5

Reviews

1 / 20
4.0
Okay

Ramón,Feb 2025

ICN - SGN

The same as my experience from NYC to Incheon, just 1 EVER LASTING LONG LINE. No group calling out anything, just telling everyone to line up.
KLM
7.8
Good
1,327 reviews
Asiana Airlines
8.2
Very good
438 reviews

Food

8.0

Comfort

8.0

Entertainment

7.7

Boarding

8.3

Overall

8.2

Crew

8.5

Reviews

1 / 20
4.0
Okay

Ramón,Feb 2025

ICN - SGN

The same as my experience from NYC to Incheon, just 1 EVER LASTING LONG LINE. No group calling out anything, just telling everyone to line up.
Finnair
7.6
Good
1,269 reviews
Asiana Airlines
8.2
Very good
438 reviews

Food

8.0

Comfort

8.0

Entertainment

7.7

Boarding

8.3

Overall

8.2

Crew

8.5

Reviews

1 / 20
4.0
Okay

Ramón,Feb 2025

ICN - SGN

The same as my experience from NYC to Incheon, just 1 EVER LASTING LONG LINE. No group calling out anything, just telling everyone to line up.
Austrian Airlines
7.6
Good
775 reviews
Asiana Airlines
8.2
Very good
438 reviews

Food

8.0

Comfort

8.0

Entertainment

7.7

Boarding

8.3

Overall

8.2

Crew

8.5

Reviews

1 / 20
4.0
Okay

Ramón,Feb 2025

ICN - SGN

The same as my experience from NYC to Incheon, just 1 EVER LASTING LONG LINE. No group calling out anything, just telling everyone to line up.

Related info for your journey

Find useful and relevant information for your journey from Missouri to Spain. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What are the cheapest airlines to fly from Missouri to Spain one-way?

    The cheapest airline one-way is Iberia, with whom users have recently found tickets for as low as $475. However, be on the lookout for offers from Air Canada and United Airlines, as they are both options that can get you from Missouri to Spain for a low price.

  • Can I find deals for flights from Missouri to Spain that include hotel bookings?

    Yes. In addition to deals on Missouri to Spain flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Missouri to Spain?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Missouri to Spain.

  • Can I find deals for business class flights from Missouri to Spain?

    Yes. Cheapflights offers flight deals from Missouri to Spain by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Missouri to Spain?

    Currently, November is the cheapest month in which you can book a flight from Missouri to Spain (average of $543). Flying from Missouri to Spain in June is currently the most expensive (average of $1,101). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

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Alternative routes for Missouri to Spain

See prices for flight routes from nearby airports that may be better suited for you.
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Top 9 airlines flying from Missouri to Spain

Discover the top 9 airlines that operate flights from Missouri to Spain. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated April 17, 2025.
AirlineCheapestAverageFlexibilityOn-time
LufthansaCheapest$530Average$1,132FlexibilityNo cancel feeOn-time76%
KLMCheapest$540Average$882FlexibilityNo cancel feeOn-time75%
United AirlinesCheapest$542Average$1,087FlexibilityNo cancel feeOn-time69%
British AirwaysCheapest$545Average$960FlexibilityNo cancel feeOn-time70%
American AirlinesCheapest$554Average$1,083FlexibilityNo cancel feeOn-time71%
DeltaCheapest$557Average$1,097FlexibilityNo cancel feeOn-timeN/A
IberiaCheapest$558Average$1,089FlexibilityNo cancel feeOn-time77%
Air FranceCheapest$571Average$890FlexibilityNo cancel feeOn-time77%
Air CanadaCheapest$670Average$1,113FlexibilityNo cancel feeOn-time67%

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