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$488+ Cheap flights from Knoxville (TYS) to Spain

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 9/23. Fares are subject to change and may not be available on all flights or dates of travel.
TYS — MAD
Apr 22 — Apr 291
Tue 4/22
Tue 4/29
1 adult, Economy
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Cheap flight deals from Knoxville to Spain

Keep the following information in mind while searching for Knoxville to Spain flight deals. Data was last updated April 17, 2025.

Round-trip from

$741
(United Airlines)

One-way from

$488
(American Airlines)

Popular in

December

Cheapest in

November

Average price

$863
From Knoxville McGhee Tyson to Spain
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One-way flight from Knoxville McGhee Tyson to Spain
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High demand for flights, 1% potential price rise
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Cheapest flight prices on average. 4% potential price decrease ($44 potential savings vs. average RT price).
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Average for round-trip flights in April 2025
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Find flight deals from Knoxville to Spain

Cheapest flights from Knoxville to Spain
Explore the most affordable flight options available from Knoxville to Spain. Find the lowest fares from popular airlines and budget airlines, with prices last updated on April 17, 2025.

This United deal was found by Cheapflights users on 4/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/45:39 pmTYS - BCN
1 stop13h 26mMultiple Airlines
Thu 11/1312:15 pmBCN - TYS
2 stops41h 27mMultiple Airlines
Deal found 4/15$549
This oojo deal was found by Cheapflights users on 4/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure oojo is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/46:54 pmTYS - BCN
2 stops18h 56mBritish Airways
Thu 11/136:40 amBCN - TYS
2 stops16h 59mBritish Airways
Deal found 4/16$597
This United Airlines deal was found by Cheapflights users on 4/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/410:35 amTYS - BCN
1 stop20h 30mUnited Airlines
Thu 11/1312:15 pmBCN - TYS
2 stops34h 34mUnited Airlines
Deal found 4/16$599
This Delta deal was found by Cheapflights users on 4/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 5/45:30 amTYS - BCN
1 stop21h 50mDelta
Tue 5/202:10 pmBCN - TYS
1 stop32h 58mDelta
Deal found 4/17$787
This United Airlines deal was found by Cheapflights users on 4/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/147:00 amTYS - MAD
2 stops19h 20mUnited Airlines
Thu 5/2212:45 pmMAD - TYS
2 stops17h 14mUnited Airlines
Deal found 4/17$803
This Delta deal was found by Cheapflights users on 4/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/1411:35 amTYS - MAD
2 stops17h 45mDelta
Thu 5/2210:05 amMAD - TYS
1 stop17h 53mDelta
Deal found 4/17$814
This Finnair deal was found by Cheapflights users on 4/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Finnair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/1411:43 amTYS - MAD
1 stop14h 12mMultiple Airlines
Thu 5/2211:30 amMAD - TYS
1 stop16h 50mMultiple Airlines
Deal found 4/17$846
This Gotogate deal was found by Cheapflights users on 4/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Gotogate is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 5/45:50 amTYS - BCN
2 stops21h 30mAir Canada
Tue 5/201:15 pmBCN - TYS
2 stops33h 39mAir Canada
Deal found 4/17$851
This American Airlines deal was found by Cheapflights users on 4/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 6/38:00 amTYS - BCN
1 stop19h 05mAmerican Airlines
Tue 6/2412:50 pmBCN - TYS
2 stops15h 21mAmerican Airlines
Deal found 4/16$1,017
This Air Canada deal was found by Cheapflights users on 4/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Air Canada is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 7/225:45 amTYS - MAD
3 stops18h 55mAir Canada
Thu 7/3112:30 pmMAD - TYS
3 stops17h 29mAir Canada
Deal found 4/17$1,069
This United Airlines deal was found by Cheapflights users on 4/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 6/267:00 amTYS - AGP
2 stops18h 35mUnited Airlines
Fri 7/49:35 amAGP - TYS
2 stops35h 23mUnited Airlines
Deal found 4/16$1,192
This Gurufare deal was found by Cheapflights users on 4/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Gurufare is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 6/110:55 amTYS - MAD
1 stop16h 40mBritish Airways
Sun 6/81:45 pmMAD - TYS
1 stop13h 14mBritish Airways
Deal found 4/16$1,234

Cheapflights Fare Finder

Customize your flight search to find flights from Knoxville to Spain that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated April 17, 2025.
Use the filters below to find and compare flights from Knoxville to Spain that are best for you.

Fly from

Knoxville

Fly to

Spain

Route

Depart

Return

Price

KnoxvilleBarcelona

TYS - BCN

TYSBCN

Knoxville McGhee Tyson

Wed 9/10

7:00 am-7:50 am

2 stops18h 50m

Barcelona-El Prat

Sun 9/21

1:15 pm-10:42 pm

2 stops39h 27m

$741

KnoxvilleBarcelona

TYS - BCN

TYSBCN

Knoxville McGhee Tyson

Wed 9/10

4:02 pm-9:05 am

1 stop11h 03m

Barcelona-El Prat

Sun 9/21

2:00 pm-5:27 pm

1 stop33h 27m

$761

KnoxvilleBarcelona

TYS - BCN

TYSBCN

Knoxville McGhee Tyson

Mon 5/5

7:15 am-7:40 am

2 stops42h 25m

Barcelona-El Prat

Tue 5/20

6:30 pm-12:22 pm

1 stop23h 52m

$765

KnoxvilleBarcelona

TYS - BCN

TYSBCN

Knoxville McGhee Tyson

Sun 5/4

5:30 am-9:20 am

1 stop21h 50m

Barcelona-El Prat

Tue 5/20

2:10 pm-5:08 pm

1 stop32h 58m

$787

KnoxvilleMadrid

TYS - MAD

TYSMAD

Knoxville McGhee Tyson

Wed 5/14

7:00 am-8:20 am

2 stops19h 20m

Madrid Barajas

Thu 5/22

12:45 pm-11:59 pm

2 stops17h 14m

$803

KnoxvilleMadrid

TYS - MAD

TYSMAD

Knoxville McGhee Tyson

Wed 5/14

11:35 am-11:20 am

2 stops17h 45m

Madrid Barajas

Thu 5/22

10:05 am-9:58 pm

1 stop17h 53m

$814

KnoxvilleMadrid

TYS - MAD

TYSMAD

Knoxville McGhee Tyson

Wed 5/14

11:43 am-7:55 am

1 stop14h 12m

Madrid Barajas

Thu 5/22

11:30 am-10:20 pm

1 stop16h 50m

$846

KnoxvilleBarcelona

TYS - BCN

TYSBCN

Knoxville McGhee Tyson

Sun 5/4

5:50 am-9:20 am

2 stops21h 30m

Barcelona-El Prat

Tue 5/20

1:15 pm-4:54 pm

2 stops33h 39m

$851

KnoxvilleBarcelona

TYS - BCN

TYSBCN

Knoxville McGhee Tyson

Tue 6/3

10:05 am-6:45 am

2 stops14h 40m

Barcelona-El Prat

Tue 6/24

12:50 pm-10:11 pm

2 stops15h 21m

$1,017

KnoxvilleMadrid

TYS - MAD

TYSMAD

Knoxville McGhee Tyson

Tue 7/22

5:45 am-6:40 am

3 stops18h 55m

Madrid Barajas

Thu 7/31

12:30 pm-11:59 pm

3 stops17h 29m

$1,069

Flights are sorted by cheapest round-trip flights first.

Deals found on 4/16

Showing 1-10 of 19 results
1
2

Best time to book a flight from Knoxville to Spain

Have a flexible travel schedule? Discover the best time to fly to Spain from Knoxville with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Knoxville to Spain

What is the cheapest month to book a flight from Knoxville to Spain?

Currently, November is the cheapest month in which you can book a flight from Knoxville to Spain (average of $543). Flying from Knoxville to Spain in June is currently the most expensive (average of $1,101). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from TYS to ES?

Find hourly flight availability from Knoxville to Spain. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated April 17, 2025.

When flying from Knoxville to Spain, the time of day you decide to fly out makes little to no difference towards the overall price you’ll pay on tickets.

Rainfall in Spain by month

Plan your trip to Spain by taking into account the average rainfall totals by month.

In terms of precipitation, rainfall in Spain ranges from 0.8 - 3.6 inches per month. October is typically the wettest month, when rainfall can reach 3.6 in. July is typically the driest time to visit Spain when rainfall is around 0.8 in.

Temperature in Spain by month

Plan your trip to Spain by taking into account the average temperature totals by month.

If weather is an important factor for your trip to Spain, use this chart to help with planning. For those seeking warmer temperatures, August is the ideal time of year to visit, when temperatures reach an average of 75.2 F. Travelers looking to avoid the cold should look outside of January, when temperatures are typically at their lowest (around 48.2 F).

Reviews of airlines servicing Spain

Get insights into the airlines that provide service to Spain. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Spain. Reviews last updated April 17, 2025.
Peruse reviews from past customers who have flown with Delta, KLM and Finnair from Knoxville to Spain to help guide your decision. Users can see the overall rating for each airline as well as how each is rated in terms of entertainment options, comfort, food, crew/service, and boarding process.
Delta
8.0
Very good
7,916 reviews

Comfort

7.9

Boarding

8.2

Crew

8.5

Food

7.3

Entertainment

7.9

Overall

8.0

Reviews

1 / 20
10.0
Excellent

Aaron,Oct 2024

LAX - LHR

This was a flight operated by Virgin Atlantic in their Upper Class cabin. Overall, an outstanding experience.
Delta
8.0
Very good
7,916 reviews
Delta
8.0
Very good
7,916 reviews

Comfort

7.9

Boarding

8.2

Crew

8.5

Food

7.3

Entertainment

7.9

Overall

8.0

Reviews

1 / 20
10.0
Excellent

Aaron,Oct 2024

LAX - LHR

This was a flight operated by Virgin Atlantic in their Upper Class cabin. Overall, an outstanding experience.
KLM
7.8
Good
1,327 reviews
Delta
8.0
Very good
7,916 reviews

Comfort

7.9

Boarding

8.2

Crew

8.5

Food

7.3

Entertainment

7.9

Overall

8.0

Reviews

1 / 20
10.0
Excellent

Aaron,Oct 2024

LAX - LHR

This was a flight operated by Virgin Atlantic in their Upper Class cabin. Overall, an outstanding experience.
Finnair
7.6
Good
1,269 reviews
Delta
8.0
Very good
7,916 reviews

Comfort

7.9

Boarding

8.2

Crew

8.5

Food

7.3

Entertainment

7.9

Overall

8.0

Reviews

1 / 20
10.0
Excellent

Aaron,Oct 2024

LAX - LHR

This was a flight operated by Virgin Atlantic in their Upper Class cabin. Overall, an outstanding experience.
United Airlines
7.4
Good
8,667 reviews
Delta
8.0
Very good
7,916 reviews

Comfort

7.9

Boarding

8.2

Crew

8.5

Food

7.3

Entertainment

7.9

Overall

8.0

Reviews

1 / 20
10.0
Excellent

Aaron,Oct 2024

LAX - LHR

This was a flight operated by Virgin Atlantic in their Upper Class cabin. Overall, an outstanding experience.
American Airlines
7.2
Good
10,000 reviews
Delta
8.0
Very good
7,916 reviews

Comfort

7.9

Boarding

8.2

Crew

8.5

Food

7.3

Entertainment

7.9

Overall

8.0

Reviews

1 / 20
10.0
Excellent

Aaron,Oct 2024

LAX - LHR

This was a flight operated by Virgin Atlantic in their Upper Class cabin. Overall, an outstanding experience.

Related info for your journey

Find useful and relevant information for your journey from Knoxville to Spain. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly from for flights from Knoxville to Spain?

    Knoxville McGhee Tyson (TYS) is the airport you will fly out of if you book a flight from Knoxville to Spain. It is only a 11.3 mi journey to McGhee Tyson (TYS) from Knoxville’s city center.

  • What are the cheapest airlines to fly from Knoxville to Spain one-way?

    For one-way options, check prices for American Airlines. According to our data, you can fly for as low as $488. Users have also found prices from $615 and $631 on United Airlines and British Airways, respectively.

  • What are the most popular routes from Knoxville to Spain?

    The most popular route from Knoxville to Spain is Knoxville McGhee Tyson - Barcelona-El Prat. You may also consider Knoxville McGhee Tyson - Madrid Barajas or Knoxville McGhee Tyson - Malaga.

  • Can I find deals for flights from Knoxville to Spain that include hotel bookings?

    Yes. In addition to deals on Knoxville to Spain flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Knoxville to Spain?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Knoxville to Spain.

  • Can I find deals for business class flights from Knoxville to Spain?

    Yes. Cheapflights offers flight deals from Knoxville to Spain by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Knoxville to Spain?

    Currently, November is the cheapest month in which you can book a flight from Knoxville to Spain (average of $543). Flying from Knoxville to Spain in June is currently the most expensive (average of $1,101). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

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Alternative routes for Knoxville to Spain

See prices for flight routes from nearby airports that may be better suited for you.
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Top 5 airlines flying from Knoxville to Spain

Discover the top 5 airlines that operate flights from Knoxville to Spain. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated April 17, 2025.
AirlineCheapestAverageFlexibilityOn-time
KLMCheapest$530Average$890FlexibilityNo cancel feeOn-time75%
DeltaCheapest$530Average$947FlexibilityNo cancel feeOn-timeN/A
United AirlinesCheapest$562Average$1,048FlexibilityNo cancel feeOn-time69%
British AirwaysCheapest$594Average$880FlexibilityNo cancel feeOn-time70%
American AirlinesCheapest$594Average$1,255FlexibilityNo cancel feeOn-time71%

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