HomeSearch by dateVacation packagesHotelsFlight dealsCar rentalTravel tips & news
South Carolina

$51+ Cheap flights from Syracuse (SYR) to South Carolina

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 5/19. Fares are subject to change and may not be available on all flights or dates of travel.
SYR — CHS
Apr 29 — May 61
Tue 4/29
Tue 5/6
1 adult, Economy
We work with more than 300 partners to bring you better travel deals

Find cheap flights from Syracuse to South Carolina with Cheapflights

1. Tell us where you want to go

Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”

2. Select your favorite providers

We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.

3. Compare prices and book

Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.

Cheap flight deals from Syracuse to South Carolina

Keep the following information in mind while searching for Syracuse to South Carolina flight deals. Data was last updated April 24, 2025.

Most accurate provider

Mytrip
3 stars

Most trusted provider

Mytrip
3 stars

Round-trip from

$127
(Booking.com)

One-way from

$51
(Priceline)

Popular in

April

Cheapest in

May

Average price

$413

Good round-trip deal

$126 or less

Good one-way deal

$109 or less
Provider with most accurate pricing for Syracuse Hancock Intl-Myrtle Beach Intl flight deals.
Search Deals
Provider most trusted by Cheapflights users for Syracuse Hancock Intl-Myrtle Beach Intl flights.
Search Deals
From Syracuse Hancock Intl to South Carolina
Search Deals
One-way flight from Syracuse Hancock Intl to South Carolina
Search Deals
Highest demand for flights based on searches. 0% potential increase in price ($1 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 2% potential price decrease ($9 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in April 2025
Search Deals
Price to beat on a round-trip flight from Syracuse Hancock Intl to South Carolina.
Search Deals
Price to beat on a one-way flight from Syracuse Hancock Intl to South Carolina.
Search Deals

Find flight deals from Syracuse to South Carolina

Cheapest flights from Syracuse to South Carolina
Explore the most affordable flight options available from Syracuse to South Carolina. Find the lowest fares from popular airlines and budget airlines, with prices last updated on April 24, 2025.

This Booking.com deal was found by Cheapflights users on 4/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Booking.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/293:09 pmSYR - MYR
Nonstop1h 56mAllegiant Air
Sun 6/15:55 pmMYR - SYR
Nonstop1h 51mAllegiant Air
Deal found 4/23$127
This Priceline deal was found by Cheapflights users on 4/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Priceline is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 6/138:31 pmSYR - CHS
Nonstop2h 13mBreeze Airways
Mon 6/166:00 amCHS - SYR
Nonstop2h 06mBreeze Airways
Deal found 4/23$132
This American Airlines deal was found by Cheapflights users on 4/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/281:48 pmSYR - GSP
1 stop6h 38mAmerican Airlines
Sat 5/316:28 pmGSP - SYR
1 stop4h 19mAmerican Airlines
Deal found 4/22$199
This Mytrip deal was found by Cheapflights users on 4/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 6/18:36 pmSYR - MYR
1 stop23h 17mMultiple Airlines
Thu 6/55:47 pmMYR - SYR
Nonstop1h 59mMultiple Airlines
Deal found 4/22$203
This JetBlue deal was found by Cheapflights users on 4/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure JetBlue is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 6/166:00 amSYR - CHS
1 stop4h 15mJetBlue
Fri 6/206:59 pmCHS - SYR
1 stop5h 00mJetBlue
Deal found 4/23$203
This Delta deal was found by Cheapflights users on 4/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/216:25 amSYR - MYR
1 stop5h 14mDelta
Wed 5/286:00 amMYR - SYR
1 stop5h 22mDelta
Deal found 4/23$210
This American Airlines deal was found by Cheapflights users on 4/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/3112:06 pmSYR - SAV
1 stop4h 24mAmerican Airlines
Sun 6/86:10 pmSAV - SYR
1 stop4h 35mAmerican Airlines
Deal found 4/22$218
This United Airlines deal was found by Cheapflights users on 4/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/285:40 pmSYR - GSP
1 stop5h 03mUnited Airlines
Sun 6/16:13 amGSP - SYR
1 stop4h 05mUnited Airlines
Deal found 4/22$224
This Delta deal was found by Cheapflights users on 4/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 7/45:00 pmSYR - CHS
1 stop5h 19mDelta
Mon 7/77:20 amCHS - SYR
1 stop4h 32mDelta
Deal found 4/23$224
This American Airlines deal was found by Cheapflights users on 4/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/301:06 pmSYR - MYR
1 stop6h 08mAmerican Airlines
Fri 6/66:14 pmMYR - SYR
2 stops5h 42mAmerican Airlines
Deal found 4/23$229
This American Airlines deal was found by Cheapflights users on 4/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 7/48:15 amSYR - CHS
2 stops9h 39mAmerican Airlines
Tue 7/87:31 amCHS - SYR
1 stop4h 58mAmerican Airlines
Deal found 4/23$229
This Delta deal was found by Cheapflights users on 4/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 6/287:05 amSYR - GSP
1 stop5h 02mDelta
Sat 7/51:00 pmGSP - SYR
1 stop6h 50mDelta
Deal found 4/22$233

Cheapflights Fare Finder

Customize your flight search to find flights from Syracuse to South Carolina that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated April 24, 2025.
Use the filters below to find and compare flights from Syracuse to South Carolina that are best for you.

Fly from

Syracuse

Fly to

South Carolina

Route

Depart

Return

Price

SyracuseMyrtle Beach

SYR - MYR

SYRMYR

Syracuse Hancock Intl

Thu 5/29

3:09 pm-5:05 pm

Nonstop1h 56m

Myrtle Beach Intl

Sun 6/1

5:55 pm-7:46 pm

Nonstop1h 51m

$127

SyracuseCharleston

SYR - CHS

SYRCHS

Syracuse Hancock Intl

Fri 6/13

8:31 pm-10:44 pm

Nonstop2h 13m

Charleston

Mon 6/16

6:00 am-8:06 am

Nonstop2h 06m

$132

SyracuseGreenville

SYR - GSP

SYRGSP

Syracuse Hancock Intl

Wed 5/28

1:48 pm-8:26 pm

1 stop6h 38m

Greenville

Sat 5/31

6:28 pm-10:47 pm

1 stop4h 19m

$199

SyracuseMyrtle Beach

SYR - MYR

SYRMYR

Syracuse Hancock Intl

Sun 6/1

8:36 pm-7:53 pm

1 stop23h 17m

Myrtle Beach Intl

Thu 6/5

5:47 pm-7:46 pm

Nonstop1h 59m

$203

SyracuseMyrtle Beach

SYR - MYR

SYRMYR

Syracuse Hancock Intl

Wed 5/21

6:25 am-11:39 am

1 stop5h 14m

Myrtle Beach Intl

Wed 5/28

6:00 am-11:22 am

1 stop5h 22m

$210

SyracuseSavannah

SYR - SAV

SYRSAV

Syracuse Hancock Intl

Sat 5/31

12:06 pm-4:30 pm

1 stop4h 24m

Savannah/Hilton Head

Sun 6/8

6:10 pm-10:45 pm

1 stop4h 35m

$218

SyracuseCharleston

SYR - CHS

SYRCHS

Syracuse Hancock Intl

Mon 5/19

6:00 am-10:59 am

1 stop4h 59m

Charleston

Wed 5/21

6:58 pm-12:16 am

1 stop5h 18m

$223

SyracuseGreenville

SYR - GSP

SYRGSP

Syracuse Hancock Intl

Wed 5/28

5:40 pm-10:43 pm

1 stop5h 03m

Greenville

Sun 6/1

6:13 am-10:18 am

1 stop4h 05m

$224

SyracuseCharleston

SYR - CHS

SYRCHS

Syracuse Hancock Intl

Fri 7/4

5:00 pm-10:19 pm

1 stop5h 19m

Charleston

Mon 7/7

7:20 am-11:52 am

1 stop4h 32m

$224

SyracuseMyrtle Beach

SYR - MYR

SYRMYR

Syracuse Hancock Intl

Fri 5/30

1:06 pm-7:14 pm

1 stop6h 08m

Myrtle Beach Intl

Fri 6/6

6:14 pm-11:56 pm

2 stops5h 42m

$229

Flights are sorted by cheapest round-trip flights first.

Deals found on 4/23

Showing 1-10 of 55 results
1
2
3
...
6

Best time to book a flight from Syracuse to South Carolina

Have a flexible travel schedule? Discover the best time to fly to South Carolina from Syracuse with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Syracuse to South Carolina

What is the cheapest month to book a flight from Syracuse to South Carolina?

Currently, August is the cheapest month in which you can book a flight from Syracuse to South Carolina (average of $217). Flying from Syracuse to South Carolina in March is currently the most expensive (average of $335). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from SYR to SC?

Find hourly flight availability from Syracuse to South Carolina. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated April 24, 2025.

Regardless of the time of day you decide to fly, the ticket price will remain around the same. Book flights from Syracuse to South Carolina as you normally would.

Rainfall in South Carolina by month

Plan your trip to South Carolina by taking into account the average rainfall totals by month.

In terms of precipitation, rainfall in South Carolina ranges from 3.0 - 6.5 inches per month. July is typically the wettest month, when rainfall can reach 6.5 in. November is typically the driest time to visit South Carolina when rainfall is around 3.0 in.

Temperature in South Carolina by month

Plan your trip to South Carolina by taking into account the average temperature totals by month.

If weather is an important factor for your trip to South Carolina, use this chart to help with planning. For those seeking warmer temperatures, July is the ideal time of year to visit, when temperatures reach an average of 78.8 F. Travelers looking to avoid the cold should look outside of January, when temperatures are typically at their lowest (around 44.6 F).

Reviews of airlines servicing South Carolina

Get insights into the airlines that provide service to South Carolina. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to South Carolina. Reviews last updated April 24, 2025.
Peruse reviews from past customers who have flown with Breeze Airways, Delta and United Airlines from Syracuse to South Carolina to help guide your decision. Users have also rated airlines in terms of entertainment options, comfort, food, crew/service, and boarding process.
Breeze Airways
8.1
Very good
159 reviews

Overall

8.1

Food

6.7

Comfort

8.2

Entertainment

6.7

Crew

8.8

Boarding

8.3

Reviews

1 / 11
10.0
Excellent

Dena,Dec 2024

LAS - BDL

It was comfortable and the crew was great! A few free snacks offered would be nice!
Breeze Airways
8.1
Very good
159 reviews
Breeze Airways
8.1
Very good
159 reviews

Overall

8.1

Food

6.7

Comfort

8.2

Entertainment

6.7

Crew

8.8

Boarding

8.3

Reviews

1 / 11
10.0
Excellent

Dena,Dec 2024

LAS - BDL

It was comfortable and the crew was great! A few free snacks offered would be nice!
Delta
8.0
Very good
7,920 reviews
Breeze Airways
8.1
Very good
159 reviews

Overall

8.1

Food

6.7

Comfort

8.2

Entertainment

6.7

Crew

8.8

Boarding

8.3

Reviews

1 / 11
10.0
Excellent

Dena,Dec 2024

LAS - BDL

It was comfortable and the crew was great! A few free snacks offered would be nice!
United Airlines
7.4
Good
8,685 reviews
Breeze Airways
8.1
Very good
159 reviews

Overall

8.1

Food

6.7

Comfort

8.2

Entertainment

6.7

Crew

8.8

Boarding

8.3

Reviews

1 / 11
10.0
Excellent

Dena,Dec 2024

LAS - BDL

It was comfortable and the crew was great! A few free snacks offered would be nice!
JetBlue
7.3
Good
2,924 reviews
Breeze Airways
8.1
Very good
159 reviews

Overall

8.1

Food

6.7

Comfort

8.2

Entertainment

6.7

Crew

8.8

Boarding

8.3

Reviews

1 / 11
10.0
Excellent

Dena,Dec 2024

LAS - BDL

It was comfortable and the crew was great! A few free snacks offered would be nice!
Allegiant Air
7.3
Good
734 reviews
Breeze Airways
8.1
Very good
159 reviews

Overall

8.1

Food

6.7

Comfort

8.2

Entertainment

6.7

Crew

8.8

Boarding

8.3

Reviews

1 / 11
10.0
Excellent

Dena,Dec 2024

LAS - BDL

It was comfortable and the crew was great! A few free snacks offered would be nice!

Related info for your journey

Find useful and relevant information for your journey from Syracuse to South Carolina. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly from for flights from Syracuse to South Carolina?

    Most people fly from Syracuse Hancock Intl (SYR) if they book a flight from Syracuse to South Carolina. Syracuse Hancock Intl is conveniently located just 4.8 mi from Syracuse’s city center.

  • How popular is this Syracuse to South Carolina flight route?

    Within the past month, 1 users have taken a look at flights from Syracuse Hancock Intl to South Carolina.

  • What are the cheapest airlines to fly from Syracuse to South Carolina one-way?

    The cheapest airline one-way is Breeze Airways, with whom users have recently found tickets for as low as $51. However, be on the lookout for offers from American Airlines and JetBlue, as they are both options that can get you from Syracuse to South Carolina for a low price.

  • What are the most popular routes from Syracuse to South Carolina?

    The most popular route from Syracuse to South Carolina is Syracuse Hancock Intl - Charlotte Douglas. You may also consider Syracuse Hancock Intl - Savannah/Hilton Head or Syracuse Hancock Intl - Charleston.

  • What are the cheapest flights from Syracuse to South Carolina?

    On average you can expect to pay $167 for a flight from Syracuse to South Carolina. The cheapest flight overall is $49 while the most popular route, (Syracuse Hancock Intl - Charlotte Douglas) is currently priced at $306.

  • Can I find deals for flights from Syracuse to South Carolina that include hotel bookings?

    Yes. In addition to deals on Syracuse to South Carolina flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Syracuse to South Carolina?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Syracuse to South Carolina.

  • Can I find deals for business class flights from Syracuse to South Carolina?

    Yes. Cheapflights offers flight deals from Syracuse to South Carolina by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Syracuse to South Carolina?

    Currently, August is the cheapest month in which you can book a flight from Syracuse to South Carolina (average of $217). Flying from Syracuse to South Carolina in March is currently the most expensive (average of $335). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Browse thousands of different options on Cheapflights for your next trip

Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.

Alternative routes for Syracuse to South Carolina

See prices for flight routes from nearby airports that may be better suited for you.
John F Kennedy Intl to Los Angeles flights
Newark to Miami flights
Newark to Fort Lauderdale flights
LaGuardia to Miami flights
LaGuardia to Fort Lauderdale flights
John F Kennedy Intl to Miami flights
Newark to Los Angeles flights
Newark to Orlando flights
Newark to Las Vegas flights
John F Kennedy Intl to Dallas/Fort Worth flights
John F Kennedy Intl to O'Hare Intl flights
LaGuardia to Dallas/Fort Worth flights
LaGuardia to O'Hare Intl flights
John F Kennedy Intl to San Francisco flights
John F Kennedy Intl to Fort Lauderdale flights
John F Kennedy Intl to Orlando flights
Newark to Dallas/Fort Worth flights
LaGuardia to Orlando flights
LaGuardia to Atlanta flights
John F Kennedy Intl to Seattle flights
Newark to Seattle flights
John F Kennedy Intl to Las Vegas flights
Newark to San Francisco flights
Newark to Hobby flights
John F Kennedy Intl to Hobby flights
Newark to O'Hare Intl flights
LaGuardia to Los Angeles flights
John F Kennedy Intl to West Palm Beach flights
LaGuardia to Hobby flights
John F Kennedy Intl to Atlanta flights
Newark to Atlanta flights
LaGuardia to Las Vegas flights
John F Kennedy Intl to Sky Harbor Intl flights
Newark to Tampa flights
Newark to Midway flights
Newark to Denver flights
John F Kennedy Intl to Midway flights
John F Kennedy Intl to Ontario flights
John F Kennedy Intl to George Bush Intcntl flights
LaGuardia to Denver flights
Newark to New Orleans flights
Newark to George Bush Intcntl flights
Newark to Sky Harbor Intl flights
John F Kennedy Intl to Austin flights
John F Kennedy Intl to San Diego flights
John F Kennedy Intl to Charlotte flights
LaGuardia to Seattle flights
Newark to Burbank flights
John F Kennedy Intl to Denver flights
John F Kennedy Intl to Honolulu flights

Top 6 airlines flying from Syracuse to South Carolina

Discover the top 6 airlines that operate flights from Syracuse to South Carolina. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated April 24, 2025.
AirlineCheapestAverageFlexibilityOn-time
JetBlueCheapest$91Average$283FlexibilityNo cancel feeOn-time62%
Breeze AirwaysCheapest$93Average$148FlexibilityNo cancel feeOn-timeN/A
Allegiant AirCheapest$100Average$200FlexibilityNo cancel feeOn-time88%
United AirlinesCheapest$188Average$405FlexibilityNo cancel feeOn-time69%
DeltaCheapest$188Average$304FlexibilityNo cancel feeOn-timeN/A
American AirlinesCheapest$197Average$360FlexibilityNo cancel feeOn-time71%

100% Free

Cheapflights is completely free to use, so you can start saving the moment you arrive.

Book with Flexibility

Our users can plan ahead with confidence and find flights with no change fees

Travel Smart

Millions of people come to us for their flight needs every year. We help make travel planning easy by providing useful insights and data-driven graphs that can inform your decisions.