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South Carolina

$90+ Cheap flights from St. Louis (STL) to South Carolina

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 4/18. Fares are subject to change and may not be available on all flights or dates of travel.
STL — CHS
abr. 2 — abr. 91
mié. 4/2
mié. 4/9
1 adult, Economy
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Cheap flight deals from St. Louis to South Carolina

Keep the following information in mind while searching for St. Louis to South Carolina flight deals. Data was last updated marzo 28, 2025.

Most accurate provider

FlightHub
3 stars

Most trusted provider

FlightHub
3 stars

Round-trip from

$160
(CheapOair)

One-way from

$90
(Booking.com)

Popular in

December

Cheapest in

October

Average price

$431

Good round-trip deal

$372 or less

Good one-way deal

$138 or less
Provider with most accurate pricing for Lambert-St Louis-Myrtle Beach Intl flight deals.
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Provider most trusted by Cheapflights users for Lambert-St Louis-Myrtle Beach Intl flights.
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From Lambert-St Louis to South Carolina
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One-way flight from Lambert-St Louis to South Carolina
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Highest demand for flights based on searches. 8% potential increase in price ($37 potential increase over avg. RT price).
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Cheapest flight prices on average. 1% potential price decrease ($7 potential savings vs. average RT price).
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Average for round-trip flights in March 2025
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Price to beat on a round-trip flight from Lambert-St Louis to South Carolina.
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Price to beat on a one-way flight from Lambert-St Louis to South Carolina.
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Find flight deals from St. Louis to South Carolina

Cheapest flights from St. Louis to South Carolina
Explore the most affordable flight options available from St. Louis to South Carolina. Find the lowest fares from popular airlines and budget airlines, with prices last updated on marzo 28, 2025.

This CheapOair deal was found by Cheapflights users on 3/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
vie. 5/165:55 pmSTL - CLT
1 stop22h 57mFrontier
lun. 5/194:21 pmCLT - STL
1 stop8h 45mFrontier
Deal found 3/27$160
This Cheapflightsfares deal was found by Cheapflights users on 3/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
jue. 4/246:10 pmSTL - CLT
1 stop5h 17mSpirit Airlines
jue. 5/16:58 amCLT - STL
1 stop11h 17mSpirit Airlines
Deal found 3/26$193
This Delta deal was found by Cheapflights users on 3/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
lun. 5/54:05 pmSTL - CHS
1 stop5h 41mDelta
mar. 5/612:32 pmCHS - STL
1 stop4h 54mDelta
Deal found 3/28$209
This CheapOair deal was found by Cheapflights users on 3/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
jue. 4/246:10 pmSTL - CLT
1 stop5h 17mMultiple Airlines
lun. 4/284:21 pmCLT - STL
1 stop8h 43mMultiple Airlines
Deal found 3/27$212
This Mytrip deal was found by Cheapflights users on 3/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mar. 4/156:10 pmSTL - CHS
1 stop23h 25mSpirit Airlines
jue. 4/2410:25 amCHS - STL
1 stop7h 50mSpirit Airlines
Deal found 3/27$219
This Delta deal was found by Cheapflights users on 3/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
sáb. 4/197:10 amSTL - CAE
1 stop5h 45mDelta
vie. 4/257:18 pmCAE - STL
1 stop5h 18mDelta
Deal found 3/26$233
This American Airlines deal was found by Cheapflights users on 3/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mar. 6/35:12 amSTL - HHH
1 stop6h 08mAmerican Airlines
mar. 6/1011:03 amHHH - STL
1 stop6h 12mAmerican Airlines
Deal found 3/27$249
This American Airlines deal was found by Cheapflights users on 3/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
vie. 5/301:59 pmSTL - CHS
1 stop4h 59mAmerican Airlines
mar. 6/312:45 pmCHS - STL
1 stop7h 44mAmerican Airlines
Deal found 3/26$253
This American Airlines deal was found by Cheapflights users on 3/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mié. 5/71:45 pmSTL - CAE
1 stop6h 18mAmerican Airlines
mar. 5/134:18 pmCAE - STL
2 stops6h 34mAmerican Airlines
Deal found 3/27$254
This Delta deal was found by Cheapflights users on 3/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mar. 4/227:10 amSTL - SAV
1 stop3h 21mDelta
vie. 4/257:55 pmSAV - STL
1 stop4h 41mDelta
Deal found 3/27$257
This Mytrip deal was found by Cheapflights users on 3/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
jue. 5/2910:10 amSTL - MYR
1 stop9h 55mMultiple Airlines
sáb. 5/3111:32 amMYR - STL
2 stops25h 38mMultiple Airlines
Deal found 3/27$275
This American Airlines deal was found by Cheapflights users on 3/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mié. 5/76:00 amSTL - CLT
1 stop8h 09mAmerican Airlines
mié. 5/288:30 pmCLT - STL
Nonstop1h 56mAmerican Airlines
Deal found 3/27$275

Cheapflights Fare Finder

Customize your flight search to find flights from St. Louis to South Carolina that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated marzo 28, 2025.
Use the filters below to find and compare flights from St. Louis to South Carolina that are best for you.

Fly from

St. Louis

Fly to

South Carolina

Route

Depart

Return

Price

St. LouisCharlotte

STL - CLT

STLCLT

Lambert-St Louis

vie. 5/16

5:55 pm-5:52 pm

1 stop22h 57m

Charlotte Douglas

lun. 5/19

4:21 pm-12:06 am

1 stop8h 45m

$160

St. LouisCharlotte

STL - CLT

STLCLT

Lambert-St Louis

jue. 4/24

6:10 pm-12:27 am

1 stop5h 17m

Charlotte Douglas

jue. 5/1

6:58 am-5:15 pm

1 stop11h 17m

$193

St. LouisCharleston

STL - CHS

STLCHS

Lambert-St Louis

lun. 5/5

4:05 pm-10:46 pm

1 stop5h 41m

Charleston

mar. 5/6

12:32 pm-4:26 pm

1 stop4h 54m

$209

St. LouisCharlotte

STL - CLT

STLCLT

Lambert-St Louis

jue. 4/24

6:10 pm-12:27 am

1 stop5h 17m

Charlotte Douglas

lun. 4/28

4:21 pm-12:04 am

1 stop8h 43m

$212

St. LouisCharleston

STL - CHS

STLCHS

Lambert-St Louis

mar. 4/15

6:10 pm-6:35 pm

1 stop23h 25m

Charleston

jue. 4/24

10:25 am-5:15 pm

1 stop7h 50m

$219

St. LouisColumbia

STL - CAE

STLCAE

Lambert-St Louis

sáb. 8/30

7:20 am-2:13 pm

1 stop5h 53m

Columbia Metropolitan

dom. 8/31

11:15 am-3:58 pm

1 stop5h 43m

$233

St. LouisHilton Head Island

STL - HHH

STLHHH

Lambert-St Louis

mar. 6/3

5:12 am-12:20 pm

1 stop6h 08m

Hilton Head Island

mar. 6/10

11:03 am-4:15 pm

1 stop6h 12m

$249

St. LouisCharleston

STL - CHS

STLCHS

Lambert-St Louis

vie. 5/30

1:59 pm-7:58 pm

1 stop4h 59m

Charleston

mar. 6/3

12:45 pm-7:29 pm

1 stop7h 44m

$253

St. LouisColumbia

STL - CAE

STLCAE

Lambert-St Louis

mié. 5/7

1:59 pm-8:20 pm

1 stop5h 21m

Columbia Metropolitan

mar. 5/13

4:18 pm-9:52 pm

2 stops6h 34m

$254

St. LouisSavannah

STL - SAV

STLSAV

Lambert-St Louis

vie. 5/9

7:06 pm-12:01 am

1 stop3h 55m

Savannah/Hilton Head

mar. 5/13

6:00 am-11:48 am

1 stop6h 48m

$257

Flights are sorted by cheapest round-trip flights first.

Deals found on 3/27

Showing 1-10 of 60 results
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Best time to book a flight from St. Louis to South Carolina

Have a flexible travel schedule? Discover the best time to fly to South Carolina from St. Louis with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from St. Louis to South Carolina

What is the cheapest month to book a flight from St. Louis to South Carolina?

Currently, August is the cheapest month in which you can book a flight from St. Louis to South Carolina (average of $217). Flying from St. Louis to South Carolina in March is currently the most expensive (average of $335). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from STL to SC?

Find hourly flight availability from St. Louis to South Carolina. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated marzo 28, 2025.

When flying from St. Louis to South Carolina, the time of day you decide to fly out makes little to no difference towards the overall price you’ll pay on tickets.

Rainfall in South Carolina by month

Plan your trip to South Carolina by taking into account the average rainfall totals by month.

In terms of precipitation, rainfall in South Carolina ranges from 3.0 - 6.5 inches per month. July is typically the wettest month, when rainfall can reach 6.5 in. November is typically the driest time to visit South Carolina when rainfall is around 3.0 in.

Temperature in South Carolina by month

Plan your trip to South Carolina by taking into account the average temperature totals by month.

If weather is an important factor for your trip to South Carolina, use this chart to help with planning. For those seeking warmer temperatures, July is the ideal time of year to visit, when temperatures reach an average of 78.8 F. Travelers looking to avoid the cold should look outside of January, when temperatures are typically at their lowest (around 44.6 F).

Reviews of airlines servicing South Carolina

Get insights into the airlines that provide service to South Carolina. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to South Carolina. Reviews last updated marzo 28, 2025.
Read reviews from past customers who have flown Southwest, Alaska Airlines and Delta from St. Louis to South Carolina. You can also see how each airline stacks up in terms of entertainment options, comfort, food, crew/service, and boarding process.
Southwest
8.1
Very good
4,273 reviews

Entertainment

7.6

Overall

8.1

Food

7.1

Comfort

8.1

Boarding

8.2

Crew

8.6

Reviews

1 / 20
8.0
Excellent

Ila,Mar 2025

HOU - DAL

Our original flight was delayed. We were able to change our flight and got home at close to the same time. Looking forward to when you have assigned seating.
Southwest
8.1
Very good
4,273 reviews
Southwest
8.1
Very good
4,273 reviews

Entertainment

7.6

Overall

8.1

Food

7.1

Comfort

8.1

Boarding

8.2

Crew

8.6

Reviews

1 / 20
8.0
Excellent

Ila,Mar 2025

HOU - DAL

Our original flight was delayed. We were able to change our flight and got home at close to the same time. Looking forward to when you have assigned seating.
Alaska Airlines
8.0
Very good
9,798 reviews
Southwest
8.1
Very good
4,273 reviews

Entertainment

7.6

Overall

8.1

Food

7.1

Comfort

8.1

Boarding

8.2

Crew

8.6

Reviews

1 / 20
8.0
Excellent

Ila,Mar 2025

HOU - DAL

Our original flight was delayed. We were able to change our flight and got home at close to the same time. Looking forward to when you have assigned seating.
Delta
8.0
Very good
7,896 reviews
Southwest
8.1
Very good
4,273 reviews

Entertainment

7.6

Overall

8.1

Food

7.1

Comfort

8.1

Boarding

8.2

Crew

8.6

Reviews

1 / 20
8.0
Excellent

Ila,Mar 2025

HOU - DAL

Our original flight was delayed. We were able to change our flight and got home at close to the same time. Looking forward to when you have assigned seating.
United Airlines
7.4
Good
8,603 reviews
Southwest
8.1
Very good
4,273 reviews

Entertainment

7.6

Overall

8.1

Food

7.1

Comfort

8.1

Boarding

8.2

Crew

8.6

Reviews

1 / 20
8.0
Excellent

Ila,Mar 2025

HOU - DAL

Our original flight was delayed. We were able to change our flight and got home at close to the same time. Looking forward to when you have assigned seating.
American Airlines
7.2
Good
10,000 reviews
Southwest
8.1
Very good
4,273 reviews

Entertainment

7.6

Overall

8.1

Food

7.1

Comfort

8.1

Boarding

8.2

Crew

8.6

Reviews

1 / 20
8.0
Excellent

Ila,Mar 2025

HOU - DAL

Our original flight was delayed. We were able to change our flight and got home at close to the same time. Looking forward to when you have assigned seating.

Related info for your journey

Find useful and relevant information for your journey from St. Louis to South Carolina. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly from for flights from St. Louis to South Carolina?

    For a flight from St. Louis to South Carolina, you will be flying from Lambert-St Louis. Lambert-St Louis (STL) is just 12.7 mi from the center of the city.

  • How popular is this St. Louis to South Carolina flight route?

    Within the past month, 5 users have taken a look at flights from Lambert-St Louis to South Carolina.

  • What are the cheapest airlines to fly from St. Louis to South Carolina one-way?

    The cheapest airlines for a one-way flight from St. Louis to South Carolina are Frontier ($90), Spirit Airlines ($91), and Delta ($105).

  • What are the most popular routes from St. Louis to South Carolina?

    While some choose either Lambert-St Louis - Charleston or Lambert-St Louis - Savannah/Hilton Head, Lambert-St Louis - Charlotte Douglas is the most popular route from St. Louis to South Carolina.

  • What are the cheapest flights from St. Louis to South Carolina?

    Looking for the cheapest flight from St. Louis to South Carolina? While on average our users pay $283, our data indicates the cheapest price to be $138. The most popular route (Lambert-St Louis - Charlotte Douglas), is priced around $193.

  • Can I find deals for flights from St. Louis to South Carolina that include hotel bookings?

    Yes. In addition to deals on St. Louis to South Carolina flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from St. Louis to South Carolina?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from St. Louis to South Carolina.

  • Can I find deals for business class flights from St. Louis to South Carolina?

    Yes. Cheapflights offers flight deals from St. Louis to South Carolina by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from St. Louis to South Carolina?

    Currently, August is the cheapest month in which you can book a flight from St. Louis to South Carolina (average of $217). Flying from St. Louis to South Carolina in March is currently the most expensive (average of $335). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

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Alternative routes for St. Louis to South Carolina

See prices for flight routes from nearby airports that may be better suited for you.
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Top 5 airlines flying from St. Louis to South Carolina

Discover the top 5 airlines that operate flights from St. Louis to South Carolina. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated marzo 28, 2025.
AirlineCheapestAverageFlexibilityOn-time
Spirit AirlinesCheapest$166Average$199FlexibilityNo cancel feeOn-time65%
American AirlinesCheapest$188Average$375FlexibilityNo cancel feeOn-time71%
DeltaCheapest$230Average$391FlexibilityNo cancel feeOn-timeN/A
SouthwestCheapest$306Average$409FlexibilityNo cancel feeOn-time63%
United AirlinesCheapest$465Average$640FlexibilityNo cancel feeOn-time69%
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