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South Carolina

$173+ Cheap flights from Santo Domingo (SDQ) to South Carolina

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 4/18. Fares are subject to change and may not be available on all flights or dates of travel.
SDQ — CHS
Apr 6 — Apr 131
Sun 4/6
Sun 4/13
1 adult, Economy
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Cheap flight deals from Santo Domingo to South Carolina

Keep the following information in mind while searching for Santo Domingo to South Carolina flight deals. Data was last updated April 1, 2025.

Most accurate provider

FlightHub
3 stars

Most trusted provider

FlightHub
3 stars

Round-trip from

$296
(Mytrip)

One-way from

$173
(Cheapflightsfares)
Provider with most accurate pricing for Santo Domingo Las Americas-Myrtle Beach Intl flight deals.
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Provider most trusted by Cheapflights users for Santo Domingo Las Americas-Myrtle Beach Intl flights.
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From Santo Domingo Las Americas to South Carolina
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One-way flight from Santo Domingo Las Americas to South Carolina
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Find flight deals from Santo Domingo to South Carolina

Cheapest flights from Santo Domingo to South Carolina
Explore the most affordable flight options available from Santo Domingo to South Carolina. Find the lowest fares from popular airlines and budget airlines, with prices last updated on April 1, 2025.

This Mytrip deal was found by Cheapflights users on 4/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 6/1712:27 pmSDQ - CLT
1 stop9h 22mFrontier
Tue 6/249:09 pmCLT - SDQ
1 stop11h 53mFrontier
Deal found 4/1$296
This CheapOair deal was found by Cheapflights users on 3/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 6/307:29 pmSDQ - CLT
1 stop12h 48mMultiple Airlines
Mon 7/711:28 amCLT - SDQ
1 stop14h 53mMultiple Airlines
Deal found 3/31$353
This eDestinos deal was found by Cheapflights users on 3/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure eDestinos is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 4/284:44 pmSDQ - CLT
1 stop7h 43mSpirit Airlines
Fri 5/26:58 amCLT - SDQ
1 stop8h 51mSpirit Airlines
Deal found 3/30$405
This Delta deal was found by Cheapflights users on 3/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/186:40 amSDQ - CHS
1 stop8h 05mDelta
Sat 1/102:30 pmCHS - SDQ
1 stop8h 29mDelta
Deal found 3/31$466
This American Airlines deal was found by Cheapflights users on 4/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/212:15 pmSDQ - CHS
1 stop6h 05mAmerican Airlines
Tue 5/1310:32 amCHS - SDQ
1 stop10h 15mAmerican Airlines
Deal found 4/1$485
This Delta deal was found by Cheapflights users on 3/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/203:45 pmSDQ - CLT
1 stop9h 12mDelta
Sat 1/311:50 amCLT - SDQ
1 stop11h 09mDelta
Deal found 3/30$502
This American Airlines deal was found by Cheapflights users on 4/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/2811:30 amSDQ - CLT
1 stop12h 34mAmerican Airlines
Tue 9/29:35 pmCLT - SDQ
1 stop13h 26mAmerican Airlines
Deal found 4/1$521
This JetBlue deal was found by Cheapflights users on 3/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure JetBlue is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 4/291:24 amSDQ - CHS
1 stop8h 12mJetBlue
Wed 5/710:57 amCHS - SDQ
1 stop8h 57mJetBlue
Deal found 3/31$558
This Copa Airlines deal was found by Cheapflights users on 3/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 6/22:05 pmSDQ - CLT
2 stops19h 45mCopa Airlines
Wed 6/186:00 amCLT - SDQ
2 stops20h 45mCopa Airlines
Deal found 3/31$608
This Mytrip deal was found by Cheapflights users on 3/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/306:30 amSDQ - CHS
3 stops26h 50mMultiple Airlines
Wed 5/77:00 amCHS - SDQ
3 stops27h 50mMultiple Airlines
Deal found 3/31$1,687

Cheapflights Fare Finder

Customize your flight search to find flights from Santo Domingo to South Carolina that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated April 1, 2025.
Use the filters below to find and compare flights from Santo Domingo to South Carolina that are best for you.

Fly from

Santo Domingo

Fly to

South Carolina

Route

Depart

Return

Price

Santo DomingoCharlotte

SDQ - CLT

SDQCLT

Santo Domingo Las Americas

Tue 6/17

12:27 pm-9:49 pm

1 stop9h 22m

Charlotte Douglas

Tue 6/24

9:09 pm-9:02 am

1 stop11h 53m

$296

Santo DomingoCharlotte

SDQ - CLT

SDQCLT

Santo Domingo Las Americas

Mon 6/30

7:29 pm-8:17 am

1 stop12h 48m

Charlotte Douglas

Mon 7/7

11:28 am-2:21 am

1 stop14h 53m

$353

Santo DomingoCharlotte

SDQ - CLT

SDQCLT

Santo Domingo Las Americas

Mon 4/28

4:44 pm-12:27 am

1 stop7h 43m

Charlotte Douglas

Fri 5/2

6:58 am-3:49 pm

1 stop8h 51m

$405

Santo DomingoCharleston

SDQ - CHS

SDQCHS

Santo Domingo Las Americas

Fri 5/2

12:15 pm-6:20 pm

1 stop6h 05m

Charleston

Tue 5/13

10:32 am-8:47 pm

1 stop10h 15m

$485

Santo DomingoCharlotte

SDQ - CLT

SDQCLT

Santo Domingo Las Americas

Tue 9/9

3:12 pm-10:20 pm

1 stop7h 08m

Charlotte Douglas

Wed 9/24

6:00 am-5:51 pm

1 stop11h 51m

$502

Santo DomingoCharlotte

SDQ - CLT

SDQCLT

Santo Domingo Las Americas

Thu 8/28

11:30 am-12:04 am

1 stop12h 34m

Charlotte Douglas

Tue 9/2

9:35 pm-11:01 am

1 stop13h 26m

$521

Santo DomingoCharleston

SDQ - CHS

SDQCHS

Santo Domingo Las Americas

Tue 4/29

1:24 am-9:36 am

1 stop8h 12m

Charleston

Wed 5/7

10:57 am-7:54 pm

1 stop8h 57m

$558

Santo DomingoCharlotte

SDQ - CLT

SDQCLT

Santo Domingo Las Americas

Mon 6/2

2:05 pm-9:50 am

2 stops19h 45m

Charlotte Douglas

Wed 6/18

6:00 am-2:45 am

2 stops20h 45m

$608

Santo DomingoCharleston

SDQ - CHS

SDQCHS

Santo Domingo Las Americas

Wed 4/30

6:30 am-9:20 am

3 stops26h 50m

Charleston

Wed 5/7

7:00 am-10:50 am

3 stops27h 50m

$1,687

Santo DomingoCharlotte

SDQ - CLT

SDQCLT

Santo Domingo Las Americas

Sat 4/12

6:10 pm-9:46 am

2 stops15h 36m

Charlotte Douglas

Wed 4/23

6:00 am-5:15 pm

2 stops35h 15m

$2,067

Flights are sorted by cheapest round-trip flights first.

Deals found on 4/1

Showing 1-10 of 22 results
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Best time to book a flight from Santo Domingo to South Carolina

Have a flexible travel schedule? Discover the best time to fly to South Carolina from Santo Domingo with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Santo Domingo to South Carolina

What is the cheapest month to book a flight from Santo Domingo to South Carolina?

Currently, August is the cheapest month in which you can book a flight from Santo Domingo to South Carolina (average of $217). Flying from Santo Domingo to South Carolina in March is currently the most expensive (average of $335). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from SDQ to SC?

Find hourly flight availability from Santo Domingo to South Carolina. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated April 1, 2025.

When flying from Santo Domingo to South Carolina, the time of day you decide to fly out makes little to no difference towards the overall price you’ll pay on tickets.

Rainfall in South Carolina by month

Plan your trip to South Carolina by taking into account the average rainfall totals by month.

In terms of precipitation, rainfall in South Carolina ranges from 3.0 - 6.5 inches per month. July is typically the wettest month, when rainfall can reach 6.5 in. November is typically the driest time to visit South Carolina when rainfall is around 3.0 in.

Temperature in South Carolina by month

Plan your trip to South Carolina by taking into account the average temperature totals by month.

If weather is an important factor for your trip to South Carolina, use this chart to help with planning. For those seeking warmer temperatures, July is the ideal time of year to visit, when temperatures reach an average of 78.8 F. Travelers looking to avoid the cold should look outside of January, when temperatures are typically at their lowest (around 44.6 F).

Reviews of airlines servicing South Carolina

Get insights into the airlines that provide service to South Carolina. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to South Carolina. Reviews last updated April 1, 2025.
See what other customers who have flown with Delta, Copa Airlines and United Airlines from Santo Domingo to South Carolina have to say. Users can see the overall rating for each airline as well as how each is rated in terms of entertainment options, comfort, food, crew/service, and boarding process.
Delta
8.0
Very good
7,898 reviews

Overall

8.0

Food

7.3

Crew

8.5

Entertainment

7.9

Comfort

7.9

Boarding

8.2

Reviews

1 / 20
10.0
Excellent

Aaron,Oct 2024

TUS - LAX

Delta has consistently been the best U.S. airline for my travels and this flight was no exception
Delta
8.0
Very good
7,898 reviews
Delta
8.0
Very good
7,898 reviews

Overall

8.0

Food

7.3

Crew

8.5

Entertainment

7.9

Comfort

7.9

Boarding

8.2

Reviews

1 / 20
10.0
Excellent

Aaron,Oct 2024

TUS - LAX

Delta has consistently been the best U.S. airline for my travels and this flight was no exception
Copa Airlines
7.6
Good
1,400 reviews
Delta
8.0
Very good
7,898 reviews

Overall

8.0

Food

7.3

Crew

8.5

Entertainment

7.9

Comfort

7.9

Boarding

8.2

Reviews

1 / 20
10.0
Excellent

Aaron,Oct 2024

TUS - LAX

Delta has consistently been the best U.S. airline for my travels and this flight was no exception
United Airlines
7.4
Good
8,615 reviews
Delta
8.0
Very good
7,898 reviews

Overall

8.0

Food

7.3

Crew

8.5

Entertainment

7.9

Comfort

7.9

Boarding

8.2

Reviews

1 / 20
10.0
Excellent

Aaron,Oct 2024

TUS - LAX

Delta has consistently been the best U.S. airline for my travels and this flight was no exception
JetBlue
7.3
Good
2,924 reviews
Delta
8.0
Very good
7,898 reviews

Overall

8.0

Food

7.3

Crew

8.5

Entertainment

7.9

Comfort

7.9

Boarding

8.2

Reviews

1 / 20
10.0
Excellent

Aaron,Oct 2024

TUS - LAX

Delta has consistently been the best U.S. airline for my travels and this flight was no exception
American Airlines
7.2
Good
10,000 reviews
Delta
8.0
Very good
7,898 reviews

Overall

8.0

Food

7.3

Crew

8.5

Entertainment

7.9

Comfort

7.9

Boarding

8.2

Reviews

1 / 20
10.0
Excellent

Aaron,Oct 2024

TUS - LAX

Delta has consistently been the best U.S. airline for my travels and this flight was no exception

Related info for your journey

Find useful and relevant information for your journey from Santo Domingo to South Carolina. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly from for flights from Santo Domingo to South Carolina?

    Santo Domingo Las Americas (SDQ) is the airport you will fly out of if you book a flight from Santo Domingo to South Carolina. It is only a 17.5 mi journey to Las Americas (SDQ) from Santo Domingo’s city center.

  • What are the cheapest airlines to fly from Santo Domingo to South Carolina one-way?

    To fly one-way, consider booking your trip with Frontier, which is currently one of the cheapest options available, starting at $173. Spirit Airlines flights start at $186 while deals on Delta start at $250 one-way.

  • What are the most popular routes from Santo Domingo to South Carolina?

    While some choose either Santo Domingo Las Americas - Charleston or Santo Domingo Las Americas - Columbia Metropolitan, Santo Domingo Las Americas - Charlotte Douglas is the most popular route from Santo Domingo to South Carolina.

  • Can I find deals for flights from Santo Domingo to South Carolina that include hotel bookings?

    Yes. In addition to deals on Santo Domingo to South Carolina flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Santo Domingo to South Carolina?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Santo Domingo to South Carolina.

  • Can I find deals for business class flights from Santo Domingo to South Carolina?

    Yes. Cheapflights offers flight deals from Santo Domingo to South Carolina by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Santo Domingo to South Carolina?

    Currently, August is the cheapest month in which you can book a flight from Santo Domingo to South Carolina (average of $217). Flying from Santo Domingo to South Carolina in March is currently the most expensive (average of $335). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

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Alternative routes for Santo Domingo to South Carolina

See prices for flight routes from nearby airports that may be better suited for you.
Santo Domingo to John F Kennedy Intl flights
Santiago de los Caballeros to John F Kennedy Intl flights
Santo Domingo to Newark flights
Santiago de los Caballeros to Newark flights
Santo Domingo to Orlando flights
Santo Domingo to Boston flights
Santo Domingo to LaGuardia flights
Santo Domingo to Miami flights
Santo Domingo to Fort Lauderdale flights
Punta Cana to John F Kennedy Intl flights
Santiago de los Caballeros to Orlando flights
Santo Domingo to Atlanta flights
Santiago de los Caballeros to LaGuardia flights
Santiago de los Caballeros to Boston flights
Punta Cana to Newark flights
Santo Domingo to Philadelphia flights
Santiago de los Caballeros to Miami flights
Punta Cana to Orlando flights
Punta Cana to Fort Lauderdale flights
Punta Cana to Miami flights
Santo Domingo to O'Hare Intl flights
Santiago de los Caballeros to Fort Lauderdale flights
Punta Cana to O'Hare Intl flights
Punta Cana to Boston flights
Santo Domingo to Dallas/Fort Worth flights
Punta Cana to LaGuardia flights
Punta Cana to Atlanta flights
Santo Domingo to Charlotte flights
Puerto Plata to John F Kennedy Intl flights
Santo Domingo to Hobby flights
Santo Domingo to Tampa flights
Santo Domingo to Los Angeles flights
Santo Domingo to Dulles Intl flights
Santo Domingo to San Francisco flights
Santo Domingo to Raleigh flights
Punta Cana to Midway flights
Punta Cana to Dulles Intl flights
Santo Domingo to George Bush Intcntl flights
Santo Domingo to Las Vegas flights
Santo Domingo to Baltimore flights
Santo Domingo to Salt Lake City flights
Punta Cana to Hobby flights
Santo Domingo to Jacksonville flights
Santo Domingo to Reagan-National flights
Santo Domingo to Midway flights
Punta Cana to Philadelphia flights
Santo Domingo to Austin flights
Punta Cana to George Bush Intcntl flights
Santiago de los Caballeros to Charlotte flights
Santo Domingo to West Palm Beach flights

Top airline flying from Santo Domingo to South Carolina

Discover the top airline that operate flights from Santo Domingo to South Carolina. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated April 1, 2025.
AirlineCheapestAverageFlexibilityOn-time
American AirlinesCheapest$286Average$575FlexibilityNo cancel feeOn-time71%

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