South Carolina

$115+ Cheap flights from Santo Domingo (SDQ) to South Carolina

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 3/10. Fares are subject to change and may not be available on all flights or dates of travel.
SDQ — CHS
feb. 4 — feb. 111
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Cheap flight deals from Santo Domingo to South Carolina

Discover tips and strategies to find the most affordable flight options for your journey from Santo Domingo (SDQ) to South Carolina (USSC). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated enero 30, 2025.

Most accurate provider

FlightHub
3 stars

Most trusted provider

FlightHub
3 stars

Round-trip from

$225
(Mytrip)

One-way from

$115
(Mytrip)
Provider with most accurate pricing for Santo Domingo Las Americas-Myrtle Beach Intl flight deals.
Provider most trusted by Cheapflights users for Santo Domingo Las Americas-Myrtle Beach Intl flights.
From Santo Domingo Las Americas to South Carolina
One-way flight from Santo Domingo Las Americas to South Carolina

Find flight deals from Santo Domingo to South Carolina

Cheapest flights from Santo Domingo to South Carolina
Explore the most affordable flight options available from Santo Domingo to South Carolina. Find the lowest fares from popular airlines and budget airlines, with prices last updated on enero 30, 2025.

This Mytrip deal was found by Cheapflights users on 1/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
jue. 2/274:00 pmSDQ - CLT
1 stop16h 08mFrontier
jue. 3/68:08 amCLT - SDQ
1 stop5h 41mFrontier
Deal found 1/30$292
This Mytrip deal was found by Cheapflights users on 1/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
vie. 3/71:04 pmSDQ - CLT
1 stop25h 42mMultiple Airlines
vie. 3/217:00 amCLT - SDQ
1 stop8h 49mMultiple Airlines
Deal found 1/30$317
This Cheapflightsfares deal was found by Cheapflights users on 1/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mié. 3/55:39 pmSDQ - CLT
1 stop7h 16mSpirit Airlines
lun. 3/106:55 amCLT - SDQ
1 stop8h 54mSpirit Airlines
Deal found 1/30$343
This JetBlue deal was found by Cheapflights users on 1/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure JetBlue is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
vie. 2/282:28 amSDQ - CHS
1 stop14h 49mJetBlue
sáb. 3/85:14 pmCHS - SDQ
1 stop9h 39mJetBlue
Deal found 1/30$436
This American Airlines deal was found by Cheapflights users on 1/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
vie. 5/26:50 amSDQ - CHS
1 stop16h 52mAmerican Airlines
mar. 5/137:00 amCHS - SDQ
1 stop6h 17mAmerican Airlines
Deal found 1/30$458
This Delta deal was found by Cheapflights users on 1/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
jue. 3/63:22 pmSDQ - CLT
1 stop7h 48mDelta
lun. 3/101:14 pmCLT - SDQ
2 stops11h 40mDelta
Deal found 1/30$490
This American Airlines deal was found by Cheapflights users on 1/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mar. 9/95:00 pmSDQ - CLT
1 stop7h 39mAmerican Airlines
mié. 9/248:27 pmCLT - SDQ
1 stop14h 34mAmerican Airlines
Deal found 1/30$523
This American Airlines deal was found by Cheapflights users on 1/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mar. 5/205:00 amSDQ - CAE
2 stops9h 58mAmerican Airlines
sáb. 5/318:14 pmCAE - SDQ
2 stops15h 01mAmerican Airlines
Deal found 1/29$592
This United Airlines deal was found by Cheapflights users on 1/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
sáb. 6/211:10 pmSDQ - CLT
1 stop8h 50mUnited Airlines
mié. 6/257:00 amCLT - SDQ
1 stop7h 10mUnited Airlines
Deal found 1/30$752
This Copa Airlines deal was found by Cheapflights users on 1/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
dom. 5/112:05 pmSDQ - CLT
2 stops19h 40mCopa Airlines
mar. 5/2010:24 amCLT - SDQ
2 stops24h 33mCopa Airlines
Deal found 1/30$770
This Delta deal was found by Cheapflights users on 1/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mar. 5/206:35 amSDQ - CAE
2 stops11h 24mDelta
sáb. 5/317:00 amCAE - SDQ
1 stop6h 05mDelta
Deal found 1/29$1,007

Find flights from Santo Domingo to South Carolina within your budget

Customize your flight search to find flights from Santo Domingo to South Carolina that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated enero 30, 2025.

Fly from

Any airport

Fly to

Any airport

Route

Depart

Return

Price

Santo DomingoCharlotte

SDQ - CLT

SDQCLT

Santo Domingo Las Americas

jue. 2/27

4:00 pm-7:08 am

1 stop16h 08m

Charlotte Douglas

jue. 3/6

8:08 am-2:49 pm

1 stop5h 41m

$292

Santo DomingoCharlotte

SDQ - CLT

SDQCLT

Santo Domingo Las Americas

vie. 3/7

1:04 pm-1:46 pm

1 stop25h 42m

Charlotte Douglas

vie. 3/21

7:00 am-3:49 pm

1 stop8h 49m

$317

Santo DomingoCharlotte

SDQ - CLT

SDQCLT

Santo Domingo Las Americas

mié. 3/5

5:39 pm-11:55 pm

1 stop7h 16m

Charlotte Douglas

lun. 3/10

6:55 am-3:49 pm

1 stop8h 54m

$343

Santo DomingoCharleston

SDQ - CHS

SDQCHS

Santo Domingo Las Americas

vie. 2/28

2:28 am-4:17 pm

1 stop14h 49m

Charleston

sáb. 3/8

5:14 pm-3:53 am

1 stop9h 39m

$436

Santo DomingoCharleston

SDQ - CHS

SDQCHS

Santo Domingo Las Americas

vie. 5/2

6:50 am-11:42 pm

1 stop16h 52m

Charleston

mar. 5/13

7:00 am-1:17 pm

1 stop6h 17m

$458

Santo DomingoCharlotte

SDQ - CLT

SDQCLT

Santo Domingo Las Americas

jue. 3/6

3:22 pm-10:10 pm

1 stop7h 48m

Charlotte Douglas

lun. 3/10

1:14 pm-12:54 am

2 stops11h 40m

$490

Santo DomingoColumbia

SDQ - CAE

SDQCAE

Santo Domingo Las Americas

mar. 5/20

5:00 am-2:58 pm

2 stops9h 58m

Columbia Metropolitan

sáb. 5/31

8:14 pm-11:15 am

2 stops15h 01m

$592

Santo DomingoCharlotte

SDQ - CLT

SDQCLT

Santo Domingo Las Americas

lun. 6/2

5:00 am-12:23 pm

1 stop7h 23m

Charlotte Douglas

mié. 6/18

9:43 pm-11:00 am

1 stop13h 17m

$679

Santo DomingoCharlotte

SDQ - CLT

SDQCLT

Santo Domingo Las Americas

sáb. 6/21

1:10 pm-10:00 pm

1 stop8h 50m

Charlotte Douglas

mié. 6/25

7:00 am-2:10 pm

1 stop7h 10m

$752

Santo DomingoCharlotte

SDQ - CLT

SDQCLT

Santo Domingo Las Americas

dom. 5/11

2:05 pm-9:45 am

2 stops19h 40m

Charlotte Douglas

mar. 5/20

10:24 am-10:57 am

2 stops24h 33m

$770

Flights are sorted by cheapest round-trip flights first.

Deals found on 1/30

Showing 1-10 of 23 results
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Best time to book a flight from Santo Domingo to South Carolina

Have a flexible travel schedule? Discover the best time to fly to South Carolina from Santo Domingo with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Travel insights for flights from Santo Domingo to South Carolina

Get recent, data-driven insights about flights from Santo Domingo to South Carolina including ideal travel times, pricing trends, and more.

What is the cheapest month to book a flight from Santo Domingo to South Carolina?

Currently, August is the cheapest month in which you can book a flight from Santo Domingo to South Carolina (average of $217). Flying from Santo Domingo to South Carolina in March is currently the most expensive (average of $335). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from SDQ to SC?

Find hourly flight availability from Santo Domingo to South Carolina. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated enero 30, 2025.

When flying from Santo Domingo to South Carolina, the time of day you decide to fly out makes little to no difference towards the overall price you’ll pay on tickets.

Rainfall in South Carolina by month

Plan your trip to South Carolina by taking into account the average rainfall totals by month.

In terms of precipitation, rainfall in South Carolina ranges from 3.0 - 6.5 inches per month. July is typically the wettest month, when rainfall can reach 6.5 in. November is typically the driest time to visit South Carolina when rainfall is around 3.0 in.

Temperature in South Carolina by month

Plan your trip to South Carolina by taking into account the average temperature totals by month.

If weather is an important factor for your trip to South Carolina, use this chart to help with planning. For those seeking warmer temperatures, July is the ideal time of year to visit, when temperatures reach an average of 78.8 F. Travelers looking to avoid the cold should look outside of January, when temperatures are typically at their lowest (around 44.6 F).

Reviews of airlines servicing South Carolina

Get insights into the airlines that provide service to South Carolina. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to South Carolina. Reviews last updated enero 30, 2025.
See what other customers who have flown with Delta, Copa Airlines and JetBlue from Santo Domingo to South Carolina have to say. Users can see the overall rating for each airline as well as how each is rated in terms of entertainment options, comfort, food, crew/service, and boarding process.
8.0
Very good

Boarding

8.2

Comfort

8.0

Entertainment

7.9

Crew

8.5

Overall

8.0

Food

7.3

Reviews

1 / 20

10.0
Excellent

Aaron,Oct 2024

TUS - LAX

Delta has consistently been the best U.S. airline for my travels and this flight was no exception

8.0
Very good
8.0
Very good

Boarding

8.2

Comfort

8.0

Entertainment

7.9

Crew

8.5

Overall

8.0

Food

7.3

Reviews

1 / 20

10.0
Excellent

Aaron,Oct 2024

TUS - LAX

Delta has consistently been the best U.S. airline for my travels and this flight was no exception

8.0
Very good

Boarding

8.2

Comfort

8.0

Entertainment

7.9

Crew

8.5

Overall

8.0

Food

7.3

Reviews

1 / 20

10.0
Excellent

Aaron,Oct 2024

TUS - LAX

Delta has consistently been the best U.S. airline for my travels and this flight was no exception

8.0
Very good

Boarding

8.2

Comfort

8.0

Entertainment

7.9

Crew

8.5

Overall

8.0

Food

7.3

Reviews

1 / 20

10.0
Excellent

Aaron,Oct 2024

TUS - LAX

Delta has consistently been the best U.S. airline for my travels and this flight was no exception

8.0
Very good

Boarding

8.2

Comfort

8.0

Entertainment

7.9

Crew

8.5

Overall

8.0

Food

7.3

Reviews

1 / 20

10.0
Excellent

Aaron,Oct 2024

TUS - LAX

Delta has consistently been the best U.S. airline for my travels and this flight was no exception

8.0
Very good

Boarding

8.2

Comfort

8.0

Entertainment

7.9

Crew

8.5

Overall

8.0

Food

7.3

Reviews

1 / 20

10.0
Excellent

Aaron,Oct 2024

TUS - LAX

Delta has consistently been the best U.S. airline for my travels and this flight was no exception

Related info for your journey

Find useful and relevant information for your journey from Santo Domingo to South Carolina. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
  • What airport do you fly from for flights from Santo Domingo to South Carolina?

    Santo Domingo Las Americas (SDQ) is the airport you will fly out of if you book a flight from Santo Domingo to South Carolina. It is only a 17.5 mi journey to Las Americas (SDQ) from Santo Domingo’s city center.

  • What are the cheapest airlines to fly from Santo Domingo to South Carolina one-way?

    To fly one-way, consider booking your trip with Frontier, which is currently one of the cheapest options available, starting at $115. Spirit Airlines flights start at $138 while deals on American Airlines start at $245 one-way.

  • What are the most popular routes from Santo Domingo to South Carolina?

  • Can I find deals for flights from Santo Domingo to South Carolina that include hotel bookings?

    Yes. In addition to deals on Santo Domingo to South Carolina flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Santo Domingo to South Carolina?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Santo Domingo to South Carolina.

  • Can I find deals for business class flights from Santo Domingo to South Carolina?

    Yes. Cheapflights offers flight deals from Santo Domingo to South Carolina by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Santo Domingo to South Carolina?

    Currently, August is the cheapest month in which you can book a flight from Santo Domingo to South Carolina (average of $217). Flying from Santo Domingo to South Carolina in March is currently the most expensive (average of $335). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

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