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$160+ Cheap flights from Santo Domingo (SDQ) to South Carolina

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 7/1. Fares are subject to change and may not be available on all flights or dates of travel.
SDQ — CHS
Apr 29 — May 61
Tue 4/29
Tue 5/6
1 adult, Economy
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Cheap flight deals from Santo Domingo to South Carolina

Keep the following information in mind while searching for Santo Domingo to South Carolina flight deals. Data was last updated April 24, 2025.

Most accurate provider

FlightHub
3 stars

Most trusted provider

eDreams
3 stars

Round-trip from

$299
(CheapOair)

One-way from

$160
(Mytrip)
Provider with most accurate pricing for Santo Domingo Las Americas-Myrtle Beach Intl flight deals.
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Provider most trusted by Cheapflights users for Santo Domingo Las Americas-Myrtle Beach Intl flights.
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From Santo Domingo Las Americas to South Carolina
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One-way flight from Santo Domingo Las Americas to South Carolina
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Find flight deals from Santo Domingo to South Carolina

Cheapest flights from Santo Domingo to South Carolina
Explore the most affordable flight options available from Santo Domingo to South Carolina. Find the lowest fares from popular airlines and budget airlines, with prices last updated on April 24, 2025.

This CheapOair deal was found by Cheapflights users on 4/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 6/712:22 pmSDQ - CLT
1 stop20h 47mFrontier
Sat 6/216:57 pmCLT - SDQ
1 stop15h 47mFrontier
Deal found 4/23$299
This Cheapflightsfares deal was found by Cheapflights users on 4/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 6/73:50 pmSDQ - CHS
1 stop16h 48mSpirit Airlines
Sat 6/219:42 amCHS - SDQ
1 stop4h 57mSpirit Airlines
Deal found 4/22$403
This Kiwi.com deal was found by Cheapflights users on 4/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 6/24:50 pmSDQ - CLT
1 stop29h 10mSpirit Airlines
Wed 6/185:18 pmCLT - SDQ
1 stop9h 03mSpirit Airlines
Deal found 4/23$403
This CheapOair deal was found by Cheapflights users on 4/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 6/216:41 pmSDQ - CLT
1 stop24h 57mMultiple Airlines
Wed 6/2511:28 amCLT - SDQ
2 stops14h 53mMultiple Airlines
Deal found 4/23$425
This Delta deal was found by Cheapflights users on 4/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/36:10 amSDQ - CHS
1 stop10h 35mDelta
Wed 10/87:45 amCHS - SDQ
1 stop6h 08mDelta
Deal found 4/23$466
This American Airlines deal was found by Cheapflights users on 4/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/38:00 amSDQ - CHS
2 stops13h 30mAmerican Airlines
Wed 10/89:19 amCHS - SDQ
2 stops10h 36mAmerican Airlines
Deal found 4/23$501
This Delta deal was found by Cheapflights users on 4/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 7/256:05 amSDQ - CLT
1 stop7h 50mDelta
Fri 8/87:00 amCLT - SDQ
1 stop6h 24mDelta
Deal found 4/23$502
This United Airlines deal was found by Cheapflights users on 4/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/61:10 pmSDQ - CLT
1 stop8h 35mUnited Airlines
Tue 6/36:26 pmCLT - SDQ
1 stop7h 24mUnited Airlines
Deal found 4/23$605
This Copa Airlines deal was found by Cheapflights users on 4/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 7/111:54 amSDQ - CLT
2 stops21h 54mCopa Airlines
Sat 7/126:00 amCLT - SDQ
2 stops20h 45mCopa Airlines
Deal found 4/23$608
This JetBlue deal was found by Cheapflights users on 4/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure JetBlue is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 6/63:11 amSDQ - CHS
1 stop13h 49mJetBlue
Sat 6/218:30 amCHS - SDQ
1 stop4h 50mJetBlue
Deal found 4/22$650
This American Airlines deal was found by Cheapflights users on 4/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 4/256:50 amSDQ - CLT
1 stop14h 44mAmerican Airlines
Mon 5/56:00 amCLT - SDQ
1 stop5h 15mAmerican Airlines
Deal found 4/24$834
This Mytrip deal was found by Cheapflights users on 4/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/2310:19 amSDQ - CHS
3 stops47h 17mMultiple Airlines
Wed 4/307:30 pmCHS - SDQ
2 stops18h 29mMultiple Airlines
Deal found 4/22$971

Cheapflights Fare Finder

Customize your flight search to find flights from Santo Domingo to South Carolina that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated April 24, 2025.
Use the filters below to find and compare flights from Santo Domingo to South Carolina that are best for you.

Fly from

Santo Domingo

Fly to

South Carolina

Route

Depart

Return

Price

Santo DomingoCharlotte

SDQ - CLT

SDQCLT

Santo Domingo Las Americas

Sat 6/7

12:22 pm-9:09 am

1 stop20h 47m

Charlotte Douglas

Sat 6/21

6:57 pm-10:44 am

1 stop15h 47m

$299

Santo DomingoCharleston

SDQ - CHS

SDQCHS

Santo Domingo Las Americas

Sat 6/7

3:50 pm-8:38 am

1 stop16h 48m

Charleston

Sat 6/21

9:42 am-2:39 pm

1 stop4h 57m

$403

Santo DomingoCharlotte

SDQ - CLT

SDQCLT

Santo Domingo Las Americas

Mon 6/2

4:50 pm-10:00 pm

1 stop29h 10m

Charlotte Douglas

Wed 6/18

5:18 pm-2:21 am

1 stop9h 03m

$403

Santo DomingoCharlotte

SDQ - CLT

SDQCLT

Santo Domingo Las Americas

Sat 6/21

6:41 pm-7:38 pm

1 stop24h 57m

Charlotte Douglas

Wed 6/25

11:28 am-2:21 am

2 stops14h 53m

$425

Santo DomingoCharleston

SDQ - CHS

SDQCHS

Santo Domingo Las Americas

Fri 10/3

6:10 am-4:45 pm

1 stop10h 35m

Charleston

Wed 10/8

7:45 am-1:53 pm

1 stop6h 08m

$466

Santo DomingoCharleston

SDQ - CHS

SDQCHS

Santo Domingo Las Americas

Fri 10/3

8:00 am-9:30 pm

2 stops13h 30m

Charleston

Wed 10/8

9:19 am-7:55 pm

2 stops10h 36m

$501

Santo DomingoCharlotte

SDQ - CLT

SDQCLT

Santo Domingo Las Americas

Fri 7/25

6:05 am-1:55 pm

1 stop7h 50m

Charlotte Douglas

Fri 8/8

7:00 am-1:24 pm

1 stop6h 24m

$502

Santo DomingoCharlotte

SDQ - CLT

SDQCLT

Santo Domingo Las Americas

Tue 5/6

1:10 pm-9:45 pm

1 stop8h 35m

Charlotte Douglas

Tue 6/3

6:26 pm-1:50 am

1 stop7h 24m

$605

Santo DomingoCharlotte

SDQ - CLT

SDQCLT

Santo Domingo Las Americas

Tue 7/1

11:54 am-9:48 am

2 stops21h 54m

Charlotte Douglas

Sat 7/12

6:00 am-2:45 am

2 stops20h 45m

$608

Santo DomingoCharleston

SDQ - CHS

SDQCHS

Santo Domingo Las Americas

Fri 6/6

3:11 am-5:00 pm

1 stop13h 49m

Charleston

Sat 6/21

8:30 am-1:20 pm

1 stop4h 50m

$650

Flights are sorted by cheapest round-trip flights first.

Deals found on 4/22

Showing 1-10 of 18 results
1
2

Best time to book a flight from Santo Domingo to South Carolina

Have a flexible travel schedule? Discover the best time to fly to South Carolina from Santo Domingo with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Santo Domingo to South Carolina

What is the cheapest time of day to fly from SDQ to SC?

Find hourly flight availability from Santo Domingo to South Carolina. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated April 24, 2025.

When flying from Santo Domingo to South Carolina, the time of day you decide to fly out makes little to no difference towards the overall price you’ll pay on tickets.

Rainfall in South Carolina by month

Plan your trip to South Carolina by taking into account the average rainfall totals by month.

In terms of precipitation, rainfall in South Carolina ranges from 3.0 - 6.5 inches per month. July is typically the wettest month, when rainfall can reach 6.5 in. November is typically the driest time to visit South Carolina when rainfall is around 3.0 in.

Temperature in South Carolina by month

Plan your trip to South Carolina by taking into account the average temperature totals by month.

If weather is an important factor for your trip to South Carolina, use this chart to help with planning. For those seeking warmer temperatures, July is the ideal time of year to visit, when temperatures reach an average of 78.8 F. Travelers looking to avoid the cold should look outside of January, when temperatures are typically at their lowest (around 44.6 F).

Reviews of airlines servicing South Carolina

Get insights into the airlines that provide service to South Carolina. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to South Carolina. Reviews last updated April 24, 2025.
See what other customers who have flown with Delta, Copa Airlines and United Airlines from Santo Domingo to South Carolina have to say. Users can see the overall rating for each airline as well as how each is rated in terms of entertainment options, comfort, food, crew/service, and boarding process.
Delta
8.0
Very good
7,920 reviews

Comfort

7.9

Food

7.3

Boarding

8.2

Crew

8.5

Overall

8.0

Entertainment

7.9

Reviews

1 / 20
10.0
Excellent

Aaron,Oct 2024

TUS - LAX

Delta has consistently been the best U.S. airline for my travels and this flight was no exception
Delta
8.0
Very good
7,920 reviews
Delta
8.0
Very good
7,920 reviews

Comfort

7.9

Food

7.3

Boarding

8.2

Crew

8.5

Overall

8.0

Entertainment

7.9

Reviews

1 / 20
10.0
Excellent

Aaron,Oct 2024

TUS - LAX

Delta has consistently been the best U.S. airline for my travels and this flight was no exception
Copa Airlines
7.6
Good
1,411 reviews
Delta
8.0
Very good
7,920 reviews

Comfort

7.9

Food

7.3

Boarding

8.2

Crew

8.5

Overall

8.0

Entertainment

7.9

Reviews

1 / 20
10.0
Excellent

Aaron,Oct 2024

TUS - LAX

Delta has consistently been the best U.S. airline for my travels and this flight was no exception
United Airlines
7.4
Good
8,685 reviews
Delta
8.0
Very good
7,920 reviews

Comfort

7.9

Food

7.3

Boarding

8.2

Crew

8.5

Overall

8.0

Entertainment

7.9

Reviews

1 / 20
10.0
Excellent

Aaron,Oct 2024

TUS - LAX

Delta has consistently been the best U.S. airline for my travels and this flight was no exception
JetBlue
7.3
Good
2,924 reviews
Delta
8.0
Very good
7,920 reviews

Comfort

7.9

Food

7.3

Boarding

8.2

Crew

8.5

Overall

8.0

Entertainment

7.9

Reviews

1 / 20
10.0
Excellent

Aaron,Oct 2024

TUS - LAX

Delta has consistently been the best U.S. airline for my travels and this flight was no exception
American Airlines
7.2
Good
10,000 reviews
Delta
8.0
Very good
7,920 reviews

Comfort

7.9

Food

7.3

Boarding

8.2

Crew

8.5

Overall

8.0

Entertainment

7.9

Reviews

1 / 20
10.0
Excellent

Aaron,Oct 2024

TUS - LAX

Delta has consistently been the best U.S. airline for my travels and this flight was no exception

Related info for your journey

Find useful and relevant information for your journey from Santo Domingo to South Carolina. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly from for flights from Santo Domingo to South Carolina?

    Santo Domingo Las Americas (SDQ) is the airport you will fly out of if you book a flight from Santo Domingo to South Carolina. It is only a 17.5 mi journey to Las Americas (SDQ) from Santo Domingo’s city center.

  • What are the cheapest airlines to fly from Santo Domingo to South Carolina one-way?

    To fly one-way, consider booking your trip with Frontier, which is currently one of the cheapest options available, starting at $160. Spirit Airlines flights start at $171 while deals on Delta start at $250 one-way.

  • What are the most popular routes from Santo Domingo to South Carolina?

    While some choose either Santo Domingo Las Americas - Charleston or Santo Domingo Las Americas - Columbia Metropolitan, Santo Domingo Las Americas - Charlotte Douglas is the most popular route from Santo Domingo to South Carolina.

  • Can I find deals for flights from Santo Domingo to South Carolina that include hotel bookings?

    Yes. In addition to deals on Santo Domingo to South Carolina flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Santo Domingo to South Carolina?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Santo Domingo to South Carolina.

  • Can I find deals for business class flights from Santo Domingo to South Carolina?

    Yes. Cheapflights offers flight deals from Santo Domingo to South Carolina by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Santo Domingo to South Carolina?

    Currently, August is the cheapest month in which you can book a flight from Santo Domingo to South Carolina (average of $217). Flying from Santo Domingo to South Carolina in March is currently the most expensive (average of $335). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

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Alternative routes for Santo Domingo to South Carolina

See prices for flight routes from nearby airports that may be better suited for you.
Santo Domingo to John F Kennedy Intl flights
Santiago de los Caballeros to John F Kennedy Intl flights
Santo Domingo to Newark flights
Santiago de los Caballeros to Newark flights
Santo Domingo to Boston flights
Santo Domingo to LaGuardia flights
Santo Domingo to Orlando flights
Santo Domingo to Miami flights
Santo Domingo to Fort Lauderdale flights
Punta Cana to John F Kennedy Intl flights
Santo Domingo to Atlanta flights
Santiago de los Caballeros to LaGuardia flights
Santiago de los Caballeros to Orlando flights
Punta Cana to Newark flights
Santiago de los Caballeros to Boston flights
Santo Domingo to Dallas/Fort Worth flights
Santo Domingo to Philadelphia flights
Santiago de los Caballeros to Miami flights
Punta Cana to Miami flights
Punta Cana to Atlanta flights
Puerto Plata to John F Kennedy Intl flights
Santo Domingo to O'Hare Intl flights
Santo Domingo to Los Angeles flights
Punta Cana to LaGuardia flights
Punta Cana to Fort Lauderdale flights
Santo Domingo to Tampa flights
Punta Cana to Boston flights
Punta Cana to Orlando flights
Santo Domingo to Love Field flights
Punta Cana to Philadelphia flights
Santo Domingo to Charlotte flights
Punta Cana to O'Hare Intl flights
Santo Domingo to Las Vegas flights
Santo Domingo to West Palm Beach flights
Santo Domingo to Hobby flights
Santo Domingo to Dulles Intl flights
Santo Domingo to Midway flights
Santo Domingo to Raleigh flights
Punta Cana to Hobby flights
Punta Cana to Dulles Intl flights
Santiago de los Caballeros to Atlanta flights
Santiago de los Caballeros to Fort Lauderdale flights
Santo Domingo to Baltimore flights
Punta Cana to George Bush Intcntl flights
Santo Domingo to Reagan-National flights
Santiago de los Caballeros to Philadelphia flights
Santo Domingo to Austin flights
Santo Domingo to George Bush Intcntl flights
Punta Cana to Los Angeles flights
Punta Cana to Dallas/Fort Worth flights

Top 2 airlines flying from Santo Domingo to South Carolina

Discover the top 2 airlines that operate flights from Santo Domingo to South Carolina. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated April 24, 2025.
AirlineCheapestAverageFlexibilityOn-time
DeltaCheapest$449Average$494FlexibilityNo cancel feeOn-timeN/A
American AirlinesCheapest$525Average$575FlexibilityNo cancel feeOn-time71%

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