$91+ Cheap flights from San Diego (SAN) to South Carolina
This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 5/10. Fares are subject to change and may not be available on all flights or dates of travel.
SAN — CHS
Mar 17 — Mar 241
1 adult, Economy
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Find cheap flights from San Diego to South Carolina with Cheapflights
1. Tell us where you want to go
Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
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Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.Cheap flight deals from San Diego to South Carolina
Keep the following information in mind while searching for San Diego to South Carolina flight deals. Data was last updated March 12, 2025.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $238 (FlightHub) |
One-way from | $91 (FlightHub) |
Popular in | December |
Cheapest in | July |
Average price | $532 |
Find flight deals from San Diego to South Carolina
Cheapest flights from San Diego to South CarolinaExplore the most affordable flight options available from San Diego to South Carolina. Find the lowest fares from popular airlines and budget airlines, with prices last updated on March 12, 2025.
Explore the most affordable flight options available from San Diego to South Carolina. Find the lowest fares from popular airlines and budget airlines, with prices last updated on March 12, 2025.
This FlightHub deal was found by Cheapflights users on 3/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure FlightHub is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 3/196:15 amSAN - CLT
2 stops15h 17mSpirit Airlines
Tue 3/2511:45 amCLT - SAN
2 stops15h 06mSpirit Airlines
Deal found 3/11![Spirit Airlines logo]()
$238
This CheapOair deal was found by Cheapflights users on 3/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/2310:52 amSAN - CLT
1 stop26h 40mFrontier
Sun 5/255:27 pmCLT - SAN
1 stop9h 32mFrontier
Deal found 3/12![Frontier logo]()
$240
This Booking.com deal was found by Cheapflights users on 3/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Booking.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 4/46:25 amSAN - CLT
1 stop8h 12mMultiple Airlines
Mon 4/215:43 pmCLT - SAN
2 stops16h 51mMultiple Airlines
Deal found 3/11![Multiple Airlines logo]()
$246
This American Airlines deal was found by Cheapflights users on 3/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 4/219:45 pmSAN - CAE
1 stop7h 36mAmerican Airlines
Sat 4/264:14 pmCAE - SAN
1 stop7h 38mAmerican Airlines
Deal found 3/11![American Airlines logo]()
$263
This Mytrip deal was found by Cheapflights users on 3/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 4/76:15 amSAN - MYR
3 stops35h 07mSpirit Airlines
Mon 4/1412:08 pmMYR - SAN
2 stops22h 26mSpirit Airlines
Deal found 3/12![Spirit Airlines logo]()
$266
This American Airlines deal was found by Cheapflights users on 3/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 4/1810:45 pmSAN - AGS
1 stop8h 58mAmerican Airlines
Sun 4/206:30 amAGS - SAN
1 stop7h 28mAmerican Airlines
Deal found 3/12![American Airlines logo]()
$267
This United Airlines deal was found by Cheapflights users on 3/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 4/510:00 pmSAN - GSP
1 stop9h 09mUnited Airlines
Tue 4/84:36 pmGSP - SAN
1 stop7h 46mUnited Airlines
Deal found 3/12![United Airlines logo]()
$287
This American Airlines deal was found by Cheapflights users on 3/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 4/810:45 pmSAN - FLO
1 stop8h 22mAmerican Airlines
Mon 4/215:00 amFLO - SAN
1 stop7h 15mAmerican Airlines
Deal found 3/12![American Airlines logo]()
$292
This Delta deal was found by Cheapflights users on 3/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/710:00 pmSAN - GSP
1 stop9h 34mDelta
Mon 5/127:49 pmGSP - SAN
1 stop6h 51mDelta
Deal found 3/12![Delta logo]()
$297
This Delta deal was found by Cheapflights users on 3/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 4/111:35 amSAN - CLT
1 stop9h 10mDelta
Wed 4/26:27 amCLT - SAN
1 stop7h 23mDelta
Deal found 3/11![Delta logo]()
$297
This FlightHub deal was found by Cheapflights users on 3/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure FlightHub is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 3/298:07 pmSAN - CHS
2 stops14h 12mSpirit Airlines
Sat 4/55:29 pmCHS - SAN
2 stops17h 12mSpirit Airlines
Deal found 3/11![Spirit Airlines logo]()
$298
This United Airlines deal was found by Cheapflights users on 3/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/1610:26 amSAN - CHS
2 stops10h 33mUnited Airlines
Tue 4/226:30 amCHS - SAN
1 stop8h 12mUnited Airlines
Deal found 3/11![United Airlines logo]()
$299
Find flights from San Diego to South Carolina within your budget
Customize your flight search to find flights from San Diego to South Carolina that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated March 12, 2025.
Fly from
San Diego
Fly to
South Carolina
Route
Depart
Return
Price
San DiegoCharlotte
SAN - CLT
SANCLT
San Diego
Wed 3/19
6:15 am-12:32 am
2 stops15h 17m
Charlotte Douglas
Tue 3/25
11:45 am-11:51 pm
2 stops15h 06m
$238
San DiegoCharlotte
SAN - CLT
SANCLT
San Diego
Fri 5/23
10:52 am-4:32 pm
1 stop26h 40m
Charlotte Douglas
Sun 5/25
5:27 pm-11:59 pm
1 stop9h 32m
$240
San DiegoCharlotte
SAN - CLT
SANCLT
San Diego
Fri 4/4
6:25 am-5:37 pm
1 stop8h 12m
Charlotte Douglas
Mon 4/21
5:43 pm-7:34 am
2 stops16h 51m
$246
San DiegoColumbia
SAN - CAE
SANCAE
San Diego
Mon 4/21
9:45 pm-8:21 am
1 stop7h 36m
Columbia Metropolitan
Sat 4/26
4:14 pm-8:52 pm
1 stop7h 38m
$263
San DiegoMyrtle Beach
SAN - MYR
SANMYR
San Diego
Mon 4/7
6:15 am-8:22 pm
3 stops35h 07m
Myrtle Beach Intl
Mon 4/14
12:08 pm-7:34 am
2 stops22h 26m
$266
San DiegoAugusta
SAN - AGS
SANAGS
San Diego
Fri 4/18
10:45 pm-10:43 am
1 stop8h 58m
Augusta Bush Field
Sun 4/20
6:30 am-10:58 am
1 stop7h 28m
$267
San DiegoGreenville
SAN - GSP
SANGSP
San Diego
Sat 4/5
10:00 pm-10:09 am
1 stop9h 09m
Greenville
Tue 4/8
4:36 pm-9:22 pm
1 stop7h 46m
$287
San DiegoFlorence
SAN - FLO
SANFLO
San Diego
Tue 4/8
10:45 pm-10:07 am
1 stop8h 22m
Florence
Mon 4/21
5:00 am-9:15 am
1 stop7h 15m
$292
San DiegoGreenville
SAN - GSP
SANGSP
San Diego
Wed 5/7
10:00 pm-10:34 am
1 stop9h 34m
Greenville
Mon 5/12
7:49 pm-11:40 pm
1 stop6h 51m
$297
San DiegoCharlotte
SAN - CLT
SANCLT
San Diego
Tue 4/1
11:35 am-11:45 pm
1 stop9h 10m
Charlotte Douglas
Wed 4/2
6:27 am-10:50 am
1 stop7h 23m
$297
Showing 1-10 of 60 results
Best time to book a flight from San Diego to South Carolina
Have a flexible travel schedule? Discover the best time to fly to South Carolina from San Diego with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Travel insights for flights from San Diego to South Carolina
Get recent, data-driven insights about flights from San Diego to South Carolina including ideal travel times, pricing trends, and more.
What is the cheapest month to book a flight from San Diego to South Carolina?
Currently, August is the cheapest month in which you can book a flight from San Diego to South Carolina (average of $217). Flying from San Diego to South Carolina in March is currently the most expensive (average of $335). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.
What is the cheapest time of day to fly from SAN to SC?
Find hourly flight availability from San Diego to South Carolina. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated March 12, 2025.
When flying from San Diego to South Carolina, the time of day you decide to fly out makes little to no difference towards the overall price you’ll pay on tickets.
Rainfall in South Carolina by month
Plan your trip to South Carolina by taking into account the average rainfall totals by month.
In terms of precipitation, rainfall in South Carolina ranges from 3.0 - 6.5 inches per month. July is typically the wettest month, when rainfall can reach 6.5 in. November is typically the driest time to visit South Carolina when rainfall is around 3.0 in.
Temperature in South Carolina by month
Plan your trip to South Carolina by taking into account the average temperature totals by month.
If weather is an important factor for your trip to South Carolina, use this chart to help with planning. For those seeking warmer temperatures, July is the ideal time of year to visit, when temperatures reach an average of 78.8 F. Travelers looking to avoid the cold should look outside of January, when temperatures are typically at their lowest (around 44.6 F).
Reviews of airlines servicing South Carolina
Get insights into the airlines that provide service to South Carolina. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to South Carolina. Reviews last updated March 12, 2025.
To help decide which airline to fly from San Diego to South Carolina, see what other customers have to say about Southwest, Alaska Airlines and Delta. Users have also rated airlines in terms of entertainment options, comfort, food, crew/service, and boarding process.
Crew
8.7
Food
7.1
Entertainment
7.6
Boarding
8.2
Comfort
8.1
Overall
8.1
Reviews
1 / 20
10.0
Merlyn,Feb 2025
LAX - SMF
Crew
8.7
Food
7.1
Entertainment
7.6
Boarding
8.2
Comfort
8.1
Overall
8.1
Reviews
1 / 20
10.0
Merlyn,Feb 2025
LAX - SMF
Crew
8.7
Food
7.1
Entertainment
7.6
Boarding
8.2
Comfort
8.1
Overall
8.1
Reviews
1 / 20
10.0
Merlyn,Feb 2025
LAX - SMF
Crew
8.7
Food
7.1
Entertainment
7.6
Boarding
8.2
Comfort
8.1
Overall
8.1
Reviews
1 / 20
10.0
Merlyn,Feb 2025
LAX - SMF
Crew
8.7
Food
7.1
Entertainment
7.6
Boarding
8.2
Comfort
8.1
Overall
8.1
Reviews
1 / 20
10.0
Merlyn,Feb 2025
LAX - SMF
Crew
8.7
Food
7.1
Entertainment
7.6
Boarding
8.2
Comfort
8.1
Overall
8.1
Reviews
1 / 20
10.0
Merlyn,Feb 2025
LAX - SMF
Related info for your journey
Find useful and relevant information for your journey from San Diego to South Carolina. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
Browse thousands of different options on Cheapflights for your next trip
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Alternative routes for San Diego to South Carolina
See prices for flight routes from nearby airports that may be better suited for you.
Top 6 airlines flying from San Diego to South Carolina
Discover the top 6 airlines that operate flights from San Diego to South Carolina. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated March 12, 2025.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$143 | Average$226 | FlexibilityNo cancel fee | On-time65% | |
| Cheapest$281 | Average$479 | FlexibilityNo cancel fee | On-time69% | |
| Cheapest$296 | Average$518 | FlexibilityNo cancel fee | On-time71% | |
| Cheapest$296 | Average$468 | FlexibilityNo cancel fee | On-timeN/A | |
| Cheapest$327 | Average$469 | FlexibilityNo cancel fee | On-time63% | |
| Cheapest$465 | Average$816 | FlexibilityNo cancel fee | On-time75% |