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South Carolina

$160+ Cheap flights from Roanoke (ROA) to South Carolina

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 5/30. Fares are subject to change and may not be available on all flights or dates of travel.
ROA — CHS
Apr 22 — Apr 291
Tue 4/22
Tue 4/29
1 adult, Economy
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Cheap flight deals from Roanoke to South Carolina

Keep the following information in mind while searching for Roanoke to South Carolina flight deals. Data was last updated April 17, 2025.

Most accurate provider

FlightHub
3 stars

Most trusted provider

eDreams
3 stars

Round-trip from

$229
(Delta)

One-way from

$160
(American Airlines)
Provider with most accurate pricing for Roanoke-Myrtle Beach Intl flight deals.
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Provider most trusted by Cheapflights users for Roanoke-Myrtle Beach Intl flights.
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From Roanoke to South Carolina
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One-way flight from Roanoke to South Carolina
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Find flight deals from Roanoke to South Carolina

Cheapest flights from Roanoke to South Carolina
Explore the most affordable flight options available from Roanoke to South Carolina. Find the lowest fares from popular airlines and budget airlines, with prices last updated on April 17, 2025.

This Delta deal was found by Cheapflights users on 4/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/167:34 pmROA - CHS
1 stop4h 10mDelta
Mon 5/198:03 pmCHS - ROA
1 stop4h 01mDelta
Deal found 4/17$229
This American Airlines deal was found by Cheapflights users on 4/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/224:05 pmROA - CLT
Nonstop1h 20mAmerican Airlines
Sat 10/2511:05 amCLT - ROA
Nonstop1h 11mAmerican Airlines
Deal found 4/17$283
This Mytrip deal was found by Cheapflights users on 4/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 6/18:22 pmROA - MYR
2 stops18h 57mAllegiant Air
Fri 6/63:59 pmMYR - ROA
2 stops22h 37mAllegiant Air
Deal found 4/16$365
This Delta deal was found by Cheapflights users on 4/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 6/17:34 pmROA - MYR
1 stop4h 25mDelta
Fri 6/67:55 pmMYR - ROA
1 stop4h 09mDelta
Deal found 4/16$399
This American Airlines deal was found by Cheapflights users on 4/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/22:55 pmROA - CHS
1 stop4h 33mAmerican Airlines
Sun 5/48:18 pmCHS - ROA
1 stop3h 18mAmerican Airlines
Deal found 4/17$429
This United Airlines deal was found by Cheapflights users on 4/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 6/37:40 pmROA - CHS
1 stop4h 19mUnited Airlines
Tue 6/105:50 amCHS - ROA
1 stop3h 57mUnited Airlines
Deal found 4/16$469
This American Airlines deal was found by Cheapflights users on 4/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/16:10 amROA - MYR
1 stop6h 12mAmerican Airlines
Mon 5/56:19 pmMYR - ROA
1 stop3h 37mAmerican Airlines
Deal found 4/16$493
This United Airlines deal was found by Cheapflights users on 4/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/197:55 pmROA - CLT
1 stop18h 09mUnited Airlines
Mon 9/227:47 pmCLT - ROA
1 stop18h 16mUnited Airlines
Deal found 4/17$497
This Mytrip deal was found by Cheapflights users on 4/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/26:04 pmROA - CHS
2 stops27h 25mMultiple Airlines
Sun 5/43:56 pmCHS - ROA
2 stops28h 13mMultiple Airlines
Deal found 4/17$548
This United Airlines deal was found by Cheapflights users on 4/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/25:30 pmROA - MYR
2 stops22h 33mUnited Airlines
Tue 5/63:15 pmMYR - ROA
1 stop6h 09mUnited Airlines
Deal found 4/17$722
This Mytrip deal was found by Cheapflights users on 4/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 4/213:16 pmROA - MYR
2 stops27h 07mMultiple Airlines
Wed 4/235:59 pmMYR - ROA
3 stops20h 40mMultiple Airlines
Deal found 4/17$794
This Mytrip deal was found by Cheapflights users on 4/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 4/183:16 pmROA - CLT
3 stops33h 11mMultiple Airlines
Sun 4/2012:12 pmCLT - ROA
2 stops26h 14mMultiple Airlines
Deal found 4/17$1,030

Cheapflights Fare Finder

Customize your flight search to find flights from Roanoke to South Carolina that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated April 17, 2025.
Use the filters below to find and compare flights from Roanoke to South Carolina that are best for you.

Fly from

Roanoke

Fly to

South Carolina

Route

Depart

Return

Price

RoanokeCharleston

ROA - CHS

ROACHS

Roanoke

Fri 5/16

7:34 pm-11:44 pm

1 stop4h 10m

Charleston

Mon 5/19

8:03 pm-12:04 am

1 stop4h 01m

$229

RoanokeCharleston

ROA - CHS

ROACHS

Roanoke

Tue 6/3

6:20 am-10:14 am

1 stop3h 54m

Charleston

Tue 6/10

5:50 am-9:47 am

1 stop3h 57m

$304

RoanokeCharlotte

ROA - CLT

ROACLT

Roanoke

Fri 9/19

2:21 pm-3:40 pm

Nonstop1h 19m

Charlotte Douglas

Mon 9/22

11:05 am-12:15 pm

Nonstop1h 10m

$313

RoanokeMyrtle Beach

ROA - MYR

ROAMYR

Roanoke

Sun 6/1

8:22 pm-3:19 pm

2 stops18h 57m

Myrtle Beach Intl

Fri 6/6

3:59 pm-2:36 pm

2 stops22h 37m

$365

RoanokeMyrtle Beach

ROA - MYR

ROAMYR

Roanoke

Sun 6/1

7:34 pm-11:59 pm

1 stop4h 25m

Myrtle Beach Intl

Fri 6/6

7:55 pm-12:04 am

1 stop4h 09m

$399

RoanokeCharleston

ROA - CHS

ROACHS

Roanoke

Fri 5/2

2:55 pm-7:28 pm

1 stop4h 33m

Charleston

Sun 5/4

8:18 pm-11:36 pm

1 stop3h 18m

$429

RoanokeMyrtle Beach

ROA - MYR

ROAMYR

Roanoke

Thu 5/1

6:10 am-12:22 pm

1 stop6h 12m

Myrtle Beach Intl

Mon 5/5

6:19 pm-9:56 pm

1 stop3h 37m

$493

RoanokeCharlotte

ROA - CLT

ROACLT

Roanoke

Fri 9/19

7:55 pm-2:04 pm

1 stop18h 09m

Charlotte Douglas

Mon 9/22

7:47 pm-2:03 pm

1 stop18h 16m

$497

RoanokeCharleston

ROA - CHS

ROACHS

Roanoke

Fri 5/2

6:04 pm-9:29 pm

2 stops27h 25m

Charleston

Sun 5/4

3:56 pm-8:09 pm

2 stops28h 13m

$548

RoanokeMyrtle Beach

ROA - MYR

ROAMYR

Roanoke

Fri 5/2

5:30 pm-4:03 pm

2 stops22h 33m

Myrtle Beach Intl

Tue 5/6

3:15 pm-9:24 pm

1 stop6h 09m

$722

Flights are sorted by cheapest round-trip flights first.

Deals found on 4/17

Showing 1-10 of 15 results
1
2

Best time to book a flight from Roanoke to South Carolina

Have a flexible travel schedule? Discover the best time to fly to South Carolina from Roanoke with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Roanoke to South Carolina

What is the cheapest month to book a flight from Roanoke to South Carolina?

Currently, August is the cheapest month in which you can book a flight from Roanoke to South Carolina (average of $217). Flying from Roanoke to South Carolina in March is currently the most expensive (average of $335). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from ROA to SC?

Find hourly flight availability from Roanoke to South Carolina. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated April 17, 2025.

Regardless of the time of day you decide to fly, the ticket price will remain around the same. Book flights from Roanoke to South Carolina as you normally would.

Rainfall in South Carolina by month

Plan your trip to South Carolina by taking into account the average rainfall totals by month.

In terms of precipitation, rainfall in South Carolina ranges from 3.0 - 6.5 inches per month. July is typically the wettest month, when rainfall can reach 6.5 in. November is typically the driest time to visit South Carolina when rainfall is around 3.0 in.

Temperature in South Carolina by month

Plan your trip to South Carolina by taking into account the average temperature totals by month.

If weather is an important factor for your trip to South Carolina, use this chart to help with planning. For those seeking warmer temperatures, July is the ideal time of year to visit, when temperatures reach an average of 78.8 F. Travelers looking to avoid the cold should look outside of January, when temperatures are typically at their lowest (around 44.6 F).

Reviews of airlines servicing South Carolina

Get insights into the airlines that provide service to South Carolina. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to South Carolina. Reviews last updated April 17, 2025.
Peruse reviews from past customers who have flown with Delta, United Airlines and Allegiant Air from Roanoke to South Carolina to help guide your decision. You can also see how each airline stacks up in terms of entertainment options, comfort, food, crew/service, and boarding process.
Delta
8.0
Very good
7,916 reviews

Boarding

8.2

Comfort

7.9

Overall

8.0

Food

7.3

Crew

8.5

Entertainment

7.9

Reviews

1 / 20
10.0
Excellent

Aaron,Oct 2024

TUS - LAX

Delta has consistently been the best U.S. airline for my travels and this flight was no exception
Delta
8.0
Very good
7,916 reviews
Delta
8.0
Very good
7,916 reviews

Boarding

8.2

Comfort

7.9

Overall

8.0

Food

7.3

Crew

8.5

Entertainment

7.9

Reviews

1 / 20
10.0
Excellent

Aaron,Oct 2024

TUS - LAX

Delta has consistently been the best U.S. airline for my travels and this flight was no exception
United Airlines
7.4
Good
8,667 reviews
Delta
8.0
Very good
7,916 reviews

Boarding

8.2

Comfort

7.9

Overall

8.0

Food

7.3

Crew

8.5

Entertainment

7.9

Reviews

1 / 20
10.0
Excellent

Aaron,Oct 2024

TUS - LAX

Delta has consistently been the best U.S. airline for my travels and this flight was no exception
Allegiant Air
7.3
Good
734 reviews
Delta
8.0
Very good
7,916 reviews

Boarding

8.2

Comfort

7.9

Overall

8.0

Food

7.3

Crew

8.5

Entertainment

7.9

Reviews

1 / 20
10.0
Excellent

Aaron,Oct 2024

TUS - LAX

Delta has consistently been the best U.S. airline for my travels and this flight was no exception
American Airlines
7.2
Good
10,000 reviews
Delta
8.0
Very good
7,916 reviews

Boarding

8.2

Comfort

7.9

Overall

8.0

Food

7.3

Crew

8.5

Entertainment

7.9

Reviews

1 / 20
10.0
Excellent

Aaron,Oct 2024

TUS - LAX

Delta has consistently been the best U.S. airline for my travels and this flight was no exception

Related info for your journey

Find useful and relevant information for your journey from Roanoke to South Carolina. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly from for flights from Roanoke to South Carolina?

    If you book a flight to South Carolina from Roanoke, you will be flying from Roanoke, which is the city’s only airport. Roanoke (ROA) is located 4.2 mi from the center of Roanoke.

  • What are the cheapest airlines to fly from Roanoke to South Carolina one-way?

    $160 is the cheapest one-way deal found within the past few days, from American Airlines. You may also be able to find cheap deals on United Airlines and Delta, with prices starting from $254 and $334, respectively.

  • What are the most popular routes from Roanoke to South Carolina?

    When deciding which route to take from Roanoke to South Carolina consider Roanoke - Charleston, Roanoke - Charlotte Douglas or Roanoke - Myrtle Beach Intl as they are the most popular.

  • Can I find deals for flights from Roanoke to South Carolina that include hotel bookings?

    Yes. In addition to deals on Roanoke to South Carolina flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Roanoke to South Carolina?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Roanoke to South Carolina.

  • Can I find deals for business class flights from Roanoke to South Carolina?

    Yes. Cheapflights offers flight deals from Roanoke to South Carolina by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Roanoke to South Carolina?

    Currently, August is the cheapest month in which you can book a flight from Roanoke to South Carolina (average of $217). Flying from Roanoke to South Carolina in March is currently the most expensive (average of $335). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

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Alternative routes for Roanoke to South Carolina

See prices for flight routes from nearby airports that may be better suited for you.
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Top airline flying from Roanoke to South Carolina

Discover the top airline that operate flights from Roanoke to South Carolina. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated April 17, 2025.
AirlineCheapestAverageFlexibilityOn-time
American AirlinesCheapest$208Average$391FlexibilityNo cancel feeOn-time71%

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