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South Carolina

$229+ Cheap flights from Panama City (PTY) to South Carolina

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 2/9. Fares are subject to change and may not be available on all flights or dates of travel.
PTY — CHS
Jan 26 — Feb 21
Sun 1/26
Sun 2/2
1 adult, Economy
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Cheap flight deals from Panama City to South Carolina

Discover tips and strategies to find the most affordable flight options for your journey from Panama City (PTY) to South Carolina (USSC). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated January 21, 2025.

Round-trip from

$436
(Delta)

One-way from

$229
(Avianca Connect)
From Panama City Tocumen Intl to South Carolina
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One-way flight from Panama City Tocumen Intl to South Carolina
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Find flight deals from Panama City to South Carolina

Cheapest flights from Panama City to South Carolina
Explore the most affordable flight options available from Panama City to South Carolina. Find the lowest fares from popular airlines and budget airlines, with prices last updated on January 21, 2025.

This Delta deal was found by Cheapflights users on 1/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/32:02 pmPTY - CHS
1 stop8h 38mDelta
Wed 5/145:30 amCHS - PTY
1 stop8h 21mDelta
Deal found 1/20$436
This American Airlines deal was found by Cheapflights users on 1/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/31:15 pmPTY - CHS
2 stops18h 19mAmerican Airlines
Wed 5/145:35 amCHS - PTY
2 stops7h 55mAmerican Airlines
Deal found 1/20$450
This American Airlines deal was found by Cheapflights users on 1/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 4/151:15 pmPTY - MYR
2 stops20h 16mAmerican Airlines
Tue 5/65:34 amMYR - PTY
2 stops7h 56mAmerican Airlines
Deal found 1/20$463
This American Airlines deal was found by Cheapflights users on 1/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/31:05 pmPTY - GSP
2 stops19h 47mAmerican Airlines
Tue 4/87:40 pmGSP - PTY
2 stops17h 35mAmerican Airlines
Deal found 1/20$472
This Kiwi.com deal was found by Cheapflights users on 1/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 3/312:03 pmPTY - CLT
1 stop11h 38mMultiple Airlines
Mon 3/1012:15 pmCLT - PTY
1 stop9h 04mMultiple Airlines
Deal found 1/21$486
This United Airlines deal was found by Cheapflights users on 1/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 2/144:40 pmPTY - CHS
1 stop23h 48mUnited Airlines
Thu 2/206:50 amCHS - PTY
1 stop7h 55mUnited Airlines
Deal found 1/20$500
This United Airlines deal was found by Cheapflights users on 1/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 2/58:55 amPTY - CLT
1 stop25h 56mUnited Airlines
Wed 2/196:30 amCLT - PTY
1 stop8h 15mUnited Airlines
Deal found 1/20$513
This American Airlines deal was found by Cheapflights users on 1/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 5/181:50 pmPTY - CLT
1 stop19h 18mAmerican Airlines
Thu 6/59:43 pmCLT - PTY
1 stop15h 41mAmerican Airlines
Deal found 1/20$553
This American Airlines deal was found by Cheapflights users on 1/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 3/243:30 pmPTY - CAE
2 stops18h 17mAmerican Airlines
Mon 4/76:32 pmCAE - PTY
2 stops18h 43mAmerican Airlines
Deal found 1/20$580
This Kiwi.com deal was found by Cheapflights users on 1/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 4/1512:03 pmPTY - MYR
1 stop27h 27mMultiple Airlines
Tue 5/65:00 amMYR - PTY
1 stop16h 19mMultiple Airlines
Deal found 1/20$606
This Delta deal was found by Cheapflights users on 1/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 3/242:20 pmPTY - CAE
1 stop8h 18mDelta
Mon 4/77:00 amCAE - PTY
1 stop6h 58mDelta
Deal found 1/20$728
This Avianca deal was found by Cheapflights users on 1/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 1/285:25 pmPTY - CLT
2 stops16h 43mAvianca
Tue 2/119:55 amCLT - PTY
2 stops14h 25mAvianca
Deal found 1/20$894

Find flights from Panama City to South Carolina within your budget

Customize your flight search to find flights from Panama City to South Carolina that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated January 21, 2025.

Fly from

Any airport

Fly to

Any airport

Route

Depart

Return

Price

Panama CityCharleston

PTY - CHS

PTYCHS

Panama City Tocumen Intl

Sat 5/3

2:02 pm-11:40 pm

1 stop8h 38m

Charleston

Wed 5/14

5:30 am-12:51 pm

1 stop8h 21m

$436

Panama CityCharleston

PTY - CHS

PTYCHS

Panama City Tocumen Intl

Sat 5/3

1:15 pm-8:34 am

2 stops18h 19m

Charleston

Wed 5/14

5:35 am-12:30 pm

2 stops7h 55m

$450

Panama CityMyrtle Beach

PTY - MYR

PTYMYR

Panama City Tocumen Intl

Tue 4/15

1:15 pm-10:31 am

2 stops20h 16m

Myrtle Beach Intl

Tue 5/6

5:34 am-12:30 pm

2 stops7h 56m

$463

Panama CityGreenville

PTY - GSP

PTYGSP

Panama City Tocumen Intl

Thu 4/3

1:05 pm-9:52 am

2 stops19h 47m

Greenville

Tue 4/8

6:00 am-12:15 pm

1 stop7h 15m

$472

Panama CityCharlotte

PTY - CLT

PTYCLT

Panama City Tocumen Intl

Mon 3/3

12:03 pm-11:41 pm

1 stop11h 38m

Charlotte Douglas

Mon 3/10

12:15 pm-8:19 pm

1 stop9h 04m

$486

Panama CityCharleston

PTY - CHS

PTYCHS

Panama City Tocumen Intl

Fri 2/14

4:40 pm-4:28 pm

1 stop23h 48m

Charleston

Thu 2/20

6:50 am-2:45 pm

1 stop7h 55m

$500

Panama CityCharlotte

PTY - CLT

PTYCLT

Panama City Tocumen Intl

Wed 2/5

8:55 am-10:51 am

1 stop25h 56m

Charlotte Douglas

Wed 2/19

6:30 am-2:45 pm

1 stop8h 15m

$513

Panama CityCharlotte

PTY - CLT

PTYCLT

Panama City Tocumen Intl

Sun 5/18

1:50 pm-10:08 am

1 stop19h 18m

Charlotte Douglas

Thu 6/5

9:43 pm-12:24 pm

1 stop15h 41m

$553

Panama CityColumbia

PTY - CAE

PTYCAE

Panama City Tocumen Intl

Mon 3/24

3:30 pm-10:47 am

2 stops18h 17m

Columbia Metropolitan

Mon 4/7

6:32 pm-12:15 pm

2 stops18h 43m

$580

Panama CityMyrtle Beach

PTY - MYR

PTYMYR

Panama City Tocumen Intl

Tue 4/15

12:03 pm-4:30 pm

1 stop27h 27m

Myrtle Beach Intl

Tue 5/6

5:00 am-8:19 pm

1 stop16h 19m

$606

Flights are sorted by cheapest round-trip flights first.

Deals found on 1/19

Showing 1-10 of 18 results
1
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Best time to book a flight from Panama City to South Carolina

Have a flexible travel schedule? Discover the best time to fly to South Carolina from Panama City with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Travel insights for flights from Panama City to South Carolina

Get recent, data-driven insights about flights from Panama City to South Carolina including ideal travel times, pricing trends, and more.

What is the cheapest time of day to fly from PTY to SC?

Find hourly flight availability from Panama City to South Carolina. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated January 21, 2025.

Regardless of the time of day you decide to fly, the ticket price will remain around the same. Book flights from Panama City to South Carolina as you normally would.

Rainfall in South Carolina by month

Plan your trip to South Carolina by taking into account the average rainfall totals by month.

In terms of precipitation, rainfall in South Carolina ranges from 3.0 - 6.5 inches per month. July is typically the wettest month, when rainfall can reach 6.5 in. November is typically the driest time to visit South Carolina when rainfall is around 3.0 in.

Temperature in South Carolina by month

Plan your trip to South Carolina by taking into account the average temperature totals by month.

If weather is an important factor for your trip to South Carolina, use this chart to help with planning. For those seeking warmer temperatures, July is the ideal time of year to visit, when temperatures reach an average of 78.8 F. Travelers looking to avoid the cold should look outside of January, when temperatures are typically at their lowest (around 44.6 F).

Reviews of airlines servicing South Carolina

Get insights into the airlines that provide service to South Carolina. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to South Carolina. Reviews last updated January 21, 2025.
Read reviews from past customers who have flown United Airlines, Delta and American Airlines from Panama City to South Carolina. In addition to providing an overall rating, users have also rated airlines in terms of entertainment options, comfort, food, crew/service, and boarding process.
Delta
8.0
Very good
8,521 reviews

Food

7.3

Boarding

8.2

Crew

8.6

Entertainment

7.9

Comfort

8.0

Overall

8.0

Reviews

1 / 10

Delta has consistently been the best U.S. airline for my travels and this flight was no exception

Delta
8.0
Very good
8,521 reviews
Delta
8.0
Very good
8,521 reviews

Food

7.3

Boarding

8.2

Crew

8.6

Entertainment

7.9

Comfort

8.0

Overall

8.0

Reviews

1 / 10

Delta has consistently been the best U.S. airline for my travels and this flight was no exception

Copa Airlines
7.7
Good
1,662 reviews
Delta
8.0
Very good
8,521 reviews

Food

7.3

Boarding

8.2

Crew

8.6

Entertainment

7.9

Comfort

8.0

Overall

8.0

Reviews

1 / 10

Delta has consistently been the best U.S. airline for my travels and this flight was no exception

United Airlines
7.4
Good
8,984 reviews
Delta
8.0
Very good
8,521 reviews

Food

7.3

Boarding

8.2

Crew

8.6

Entertainment

7.9

Comfort

8.0

Overall

8.0

Reviews

1 / 10

Delta has consistently been the best U.S. airline for my travels and this flight was no exception

American Airlines
7.2
Good
10,000 reviews
Delta
8.0
Very good
8,521 reviews

Food

7.3

Boarding

8.2

Crew

8.6

Entertainment

7.9

Comfort

8.0

Overall

8.0

Reviews

1 / 10

Delta has consistently been the best U.S. airline for my travels and this flight was no exception

Avianca
6.9
Okay
2,579 reviews
Delta
8.0
Very good
8,521 reviews

Food

7.3

Boarding

8.2

Crew

8.6

Entertainment

7.9

Comfort

8.0

Overall

8.0

Reviews

1 / 10

Delta has consistently been the best U.S. airline for my travels and this flight was no exception

Related info for your journey

Find useful and relevant information for your journey from Panama City to South Carolina. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly from for flights from Panama City to South Carolina?

    Panama City Tocumen Intl (PTY) is the airport you will fly out of if you book a flight from Panama City to South Carolina. It is only a 11.4 mi journey to Tocumen Intl (PTY) from Panama City’s city center.

  • What are the cheapest airlines to fly from Panama City to South Carolina one-way?

    The cheapest airline one-way is United Airlines, with whom users have recently found tickets for as low as $279. However, be on the lookout for offers from Delta and American Airlines, as they are both options that can get you from Panama City to South Carolina for a low price.

  • What are the most popular routes from Panama City to South Carolina?

    The most popular flight routes from Panama City to South Carolina are Panama City Tocumen Intl - Charlotte Douglas, Panama City Tocumen Intl - Columbia Metropolitan and Panama City Tocumen Intl - Charleston.

  • Can I find deals for flights from Panama City to South Carolina that include hotel bookings?

    Yes. In addition to deals on Panama City to South Carolina flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Panama City to South Carolina?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Panama City to South Carolina.

  • Can I find deals for business class flights from Panama City to South Carolina?

    Yes. Cheapflights offers flight deals from Panama City to South Carolina by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Panama City to South Carolina?

    Currently, August is the cheapest month in which you can book a flight from Panama City to South Carolina (average of $217). Flying from Panama City to South Carolina in March is currently the most expensive (average of $335). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

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Alternative routes for Panama City to South Carolina

See prices for flight routes from nearby airports that may be better suited for you.
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