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South Carolina

$262+ Cheap flights from Panama City (PTY) to South Carolina

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 7/1. Fares are subject to change and may not be available on all flights or dates of travel.
PTY — CHS
Apr 2 — Apr 91
Wed 4/2
Wed 4/9
1 adult, Economy
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Cheap flight deals from Panama City to South Carolina

Keep the following information in mind while searching for Panama City to South Carolina flight deals. Data was last updated March 28, 2025.

Most accurate provider

FlightHub
3 stars

Most trusted provider

FlightHub
3 stars

Round-trip from

$406
(Delta)

One-way from

$262
(United Airlines)
Provider with most accurate pricing for Panama City Tocumen Intl-Myrtle Beach Intl flight deals.
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Provider most trusted by Cheapflights users for Panama City Tocumen Intl-Myrtle Beach Intl flights.
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From Panama City Tocumen Intl to South Carolina
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One-way flight from Panama City Tocumen Intl to South Carolina
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Find flight deals from Panama City to South Carolina

Cheapest flights from Panama City to South Carolina
Explore the most affordable flight options available from Panama City to South Carolina. Find the lowest fares from popular airlines and budget airlines, with prices last updated on March 28, 2025.

This Delta deal was found by Cheapflights users on 3/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/32:20 pmPTY - CHS
1 stop7h 26mDelta
Wed 5/146:37 amCHS - PTY
1 stop7h 11mDelta
Deal found 3/26$406
This United Airlines deal was found by Cheapflights users on 3/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/37:55 amPTY - GSP
1 stop14h 34mUnited Airlines
Tue 4/87:05 amGSP - PTY
1 stop12h 32mUnited Airlines
Deal found 3/26$417
This American Airlines deal was found by Cheapflights users on 3/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/231:15 pmPTY - CAE
2 stops18h 06mAmerican Airlines
Wed 4/306:32 pmCAE - PTY
2 stops18h 43mAmerican Airlines
Deal found 3/26$418
This American Airlines deal was found by Cheapflights users on 3/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/31:05 pmPTY - CHS
2 stops18h 29mAmerican Airlines
Wed 5/148:43 pmCHS - PTY
2 stops16h 36mAmerican Airlines
Deal found 3/26$420
This United Airlines deal was found by Cheapflights users on 3/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/33:20 pmPTY - CLT
1 stop25h 47mUnited Airlines
Wed 4/166:13 amCLT - PTY
1 stop13h 24mUnited Airlines
Deal found 3/25$428
This Kiwi.com deal was found by Cheapflights users on 3/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/159:33 pmPTY - CLT
1 stop12h 30mMultiple Airlines
Sun 5/186:00 amCLT - PTY
1 stop14h 29mMultiple Airlines
Deal found 3/25$434
This American Airlines deal was found by Cheapflights users on 3/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/151:20 pmPTY - CLT
1 stop9h 27mAmerican Airlines
Sun 5/188:16 pmCLT - PTY
1 stop17h 03mAmerican Airlines
Deal found 3/26$437
This American Airlines deal was found by Cheapflights users on 3/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 6/161:50 pmPTY - AGS
2 stops23h 17mAmerican Airlines
Mon 6/306:14 pmAGS - PTY
2 stops19h 46mAmerican Airlines
Deal found 3/27$439
This Delta deal was found by Cheapflights users on 3/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/108:00 amPTY - CLT
1 stop10h 34mDelta
Sat 5/179:45 amCLT - PTY
1 stop11h 08mDelta
Deal found 3/26$466
This American Airlines deal was found by Cheapflights users on 3/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 8/113:16 pmPTY - GSP
2 stops18h 35mAmerican Airlines
Mon 8/185:36 amGSP - PTY
2 stops9h 39mAmerican Airlines
Deal found 3/27$484
This Delta deal was found by Cheapflights users on 3/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/232:20 pmPTY - CAE
1 stop8h 24mDelta
Wed 4/305:40 amCAE - PTY
1 stop8h 15mDelta
Deal found 3/26$987
This Avianca deal was found by Cheapflights users on 3/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 8/103:20 amPTY - GSP
2 stops16h 40mAvianca
Mon 8/189:37 amGSP - PTY
2 stops16h 08mAvianca
Deal found 3/27$1,088

Cheapflights Fare Finder

Customize your flight search to find flights from Panama City to South Carolina that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated March 28, 2025.
Use the filters below to find and compare flights from Panama City to South Carolina that are best for you.

Fly from

Panama City

Fly to

South Carolina

Route

Depart

Return

Price

Panama CityCharleston

PTY - CHS

PTYCHS

Panama City Tocumen Intl

Sat 5/3

2:20 pm-10:46 pm

1 stop7h 26m

Charleston

Wed 5/14

6:37 am-12:48 pm

1 stop7h 11m

$406

Panama CityColumbia

PTY - CAE

PTYCAE

Panama City Tocumen Intl

Wed 4/23

1:15 pm-8:21 am

2 stops18h 06m

Columbia Metropolitan

Wed 4/30

6:32 pm-12:15 pm

2 stops18h 43m

$418

Panama CityCharleston

PTY - CHS

PTYCHS

Panama City Tocumen Intl

Sat 5/3

1:05 pm-8:34 am

2 stops18h 29m

Charleston

Wed 5/14

8:43 pm-12:19 pm

2 stops16h 36m

$420

Panama CityCharlotte

PTY - CLT

PTYCLT

Panama City Tocumen Intl

Tue 4/8

3:20 pm-9:59 pm

1 stop29h 39m

Charlotte Douglas

Wed 4/16

6:13 am-2:14 pm

1 stop9h 01m

$428

Panama CityCharlotte

PTY - CLT

PTYCLT

Panama City Tocumen Intl

Thu 5/15

9:33 pm-11:03 am

1 stop12h 30m

Charlotte Douglas

Sun 5/18

6:00 am-7:29 pm

1 stop14h 29m

$434

Panama CityCharlotte

PTY - CLT

PTYCLT

Panama City Tocumen Intl

Thu 5/15

1:20 pm-11:47 pm

1 stop9h 27m

Charlotte Douglas

Sun 5/18

8:16 pm-12:19 pm

1 stop17h 03m

$437

Panama CityAugusta

PTY - AGS

PTYAGS

Panama City Tocumen Intl

Mon 6/16

1:50 pm-2:07 pm

2 stops23h 17m

Augusta Bush Field

Mon 6/30

6:14 pm-1:00 pm

2 stops19h 46m

$439

Panama CityGreenville

PTY - GSP

PTYGSP

Panama City Tocumen Intl

Mon 8/11

3:20 pm-10:00 pm

1 stop29h 40m

Greenville

Mon 8/18

5:34 pm-2:19 pm

1 stop21h 45m

$449

Panama CityGreenville

PTY - GSP

PTYGSP

Panama City Tocumen Intl

Mon 8/11

3:16 pm-10:51 am

2 stops18h 35m

Greenville

Mon 8/18

5:36 am-2:15 pm

2 stops9h 39m

$484

Panama CityColumbia

PTY - CAE

PTYCAE

Panama City Tocumen Intl

Wed 4/23

2:20 pm-11:44 pm

1 stop8h 24m

Columbia Metropolitan

Wed 4/30

5:40 am-12:55 pm

1 stop8h 15m

$987

Flights are sorted by cheapest round-trip flights first.

Deals found on 3/26

Showing 1-10 of 19 results
1
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Best time to book a flight from Panama City to South Carolina

Have a flexible travel schedule? Discover the best time to fly to South Carolina from Panama City with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Panama City to South Carolina

What is the cheapest time of day to fly from PTY to SC?

Find hourly flight availability from Panama City to South Carolina. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated March 28, 2025.

Regardless of the time of day you decide to fly, the ticket price will remain around the same. Book flights from Panama City to South Carolina as you normally would.

Rainfall in South Carolina by month

Plan your trip to South Carolina by taking into account the average rainfall totals by month.

In terms of precipitation, rainfall in South Carolina ranges from 3.0 - 6.5 inches per month. July is typically the wettest month, when rainfall can reach 6.5 in. November is typically the driest time to visit South Carolina when rainfall is around 3.0 in.

Temperature in South Carolina by month

Plan your trip to South Carolina by taking into account the average temperature totals by month.

If weather is an important factor for your trip to South Carolina, use this chart to help with planning. For those seeking warmer temperatures, July is the ideal time of year to visit, when temperatures reach an average of 78.8 F. Travelers looking to avoid the cold should look outside of January, when temperatures are typically at their lowest (around 44.6 F).

Reviews of airlines servicing South Carolina

Get insights into the airlines that provide service to South Carolina. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to South Carolina. Reviews last updated March 28, 2025.
Read reviews from past customers who have flown Delta, Copa Airlines and United Airlines from Panama City to South Carolina. In addition to providing an overall rating, users have also rated airlines in terms of entertainment options, comfort, food, crew/service, and boarding process.
Delta
8.0
Very good
7,897 reviews

Boarding

8.2

Comfort

8.0

Food

7.3

Entertainment

7.9

Overall

8.0

Crew

8.5

Reviews

1 / 20
10.0
Excellent

Aaron,Oct 2024

TUS - LAX

Delta has consistently been the best U.S. airline for my travels and this flight was no exception
Delta
8.0
Very good
7,897 reviews
Delta
8.0
Very good
7,897 reviews

Boarding

8.2

Comfort

8.0

Food

7.3

Entertainment

7.9

Overall

8.0

Crew

8.5

Reviews

1 / 20
10.0
Excellent

Aaron,Oct 2024

TUS - LAX

Delta has consistently been the best U.S. airline for my travels and this flight was no exception
Copa Airlines
7.5
Good
1,395 reviews
Delta
8.0
Very good
7,897 reviews

Boarding

8.2

Comfort

8.0

Food

7.3

Entertainment

7.9

Overall

8.0

Crew

8.5

Reviews

1 / 20
10.0
Excellent

Aaron,Oct 2024

TUS - LAX

Delta has consistently been the best U.S. airline for my travels and this flight was no exception
United Airlines
7.4
Good
8,603 reviews
Delta
8.0
Very good
7,897 reviews

Boarding

8.2

Comfort

8.0

Food

7.3

Entertainment

7.9

Overall

8.0

Crew

8.5

Reviews

1 / 20
10.0
Excellent

Aaron,Oct 2024

TUS - LAX

Delta has consistently been the best U.S. airline for my travels and this flight was no exception
American Airlines
7.2
Good
10,000 reviews
Delta
8.0
Very good
7,897 reviews

Boarding

8.2

Comfort

8.0

Food

7.3

Entertainment

7.9

Overall

8.0

Crew

8.5

Reviews

1 / 20
10.0
Excellent

Aaron,Oct 2024

TUS - LAX

Delta has consistently been the best U.S. airline for my travels and this flight was no exception
Avianca
6.7
Okay
2,300 reviews
Delta
8.0
Very good
7,897 reviews

Boarding

8.2

Comfort

8.0

Food

7.3

Entertainment

7.9

Overall

8.0

Crew

8.5

Reviews

1 / 20
10.0
Excellent

Aaron,Oct 2024

TUS - LAX

Delta has consistently been the best U.S. airline for my travels and this flight was no exception

Related info for your journey

Find useful and relevant information for your journey from Panama City to South Carolina. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly from for flights from Panama City to South Carolina?

    Panama City Tocumen Intl (PTY) is the airport you will fly out of if you book a flight from Panama City to South Carolina. It is only a 11.4 mi journey to Tocumen Intl (PTY) from Panama City’s city center.

  • What are the cheapest airlines to fly from Panama City to South Carolina one-way?

    The cheapest airline one-way is United Airlines, with whom users have recently found tickets for as low as $262. However, be on the lookout for offers from American Airlines and Delta, as they are both options that can get you from Panama City to South Carolina for a low price.

  • What are the most popular routes from Panama City to South Carolina?

    The most popular flight routes from Panama City to South Carolina are Panama City Tocumen Intl - Charlotte Douglas, Panama City Tocumen Intl - Columbia Metropolitan and Panama City Tocumen Intl - Charleston.

  • Can I find deals for flights from Panama City to South Carolina that include hotel bookings?

    Yes. In addition to deals on Panama City to South Carolina flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Panama City to South Carolina?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Panama City to South Carolina.

  • Can I find deals for business class flights from Panama City to South Carolina?

    Yes. Cheapflights offers flight deals from Panama City to South Carolina by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Panama City to South Carolina?

    Currently, August is the cheapest month in which you can book a flight from Panama City to South Carolina (average of $217). Flying from Panama City to South Carolina in March is currently the most expensive (average of $335). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

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Alternative routes for Panama City to South Carolina

See prices for flight routes from nearby airports that may be better suited for you.
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Top airline flying from Panama City to South Carolina

Discover the top airline that operate flights from Panama City to South Carolina. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated March 28, 2025.
AirlineCheapestAverageFlexibilityOn-time
American AirlinesCheapest$423Average$501FlexibilityNo cancel feeOn-time71%
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