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South Carolina

$227+ Cheap flights from Panama City (PTY) to South Carolina

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 4/6. Fares are subject to change and may not be available on all flights or dates of travel.
PTY — CHS
Feb 25 — Mar 41
Tue 2/25
Tue 3/4
1 adult, Economy
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Cheap flight deals from Panama City to South Carolina

Keep the following information in mind while searching for Panama City to South Carolina flight deals. Data was last updated February 20, 2025.

Most accurate provider

FlightHub
3 stars

Most trusted provider

FlightHub
3 stars

Round-trip from

$436
(Delta)

One-way from

$227
(Avianca Connect)
Provider with most accurate pricing for Panama City Tocumen Intl-Myrtle Beach Intl flight deals.
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Provider most trusted by Cheapflights users for Panama City Tocumen Intl-Myrtle Beach Intl flights.
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From Panama City Tocumen Intl to South Carolina
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One-way flight from Panama City Tocumen Intl to South Carolina
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Find flight deals from Panama City to South Carolina

Cheapest flights from Panama City to South Carolina
Explore the most affordable flight options available from Panama City to South Carolina. Find the lowest fares from popular airlines and budget airlines, with prices last updated on February 20, 2025.

This Delta deal was found by Cheapflights users on 2/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/32:20 pmPTY - CHS
1 stop8h 38mDelta
Wed 5/145:30 amCHS - PTY
1 stop8h 21mDelta
Deal found 2/19$436
This American Airlines deal was found by Cheapflights users on 2/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/31:05 pmPTY - CHS
2 stops18h 29mAmerican Airlines
Wed 5/147:00 amCHS - PTY
1 stop6h 15mAmerican Airlines
Deal found 2/19$450
This United Airlines deal was found by Cheapflights users on 2/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 3/203:40 pmPTY - GSP
1 stop30h 35mUnited Airlines
Thu 3/277:04 amGSP - PTY
1 stop12h 34mUnited Airlines
Deal found 2/19$455
This American Airlines deal was found by Cheapflights users on 2/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 3/191:05 pmPTY - CAE
2 stops19h 49mAmerican Airlines
Wed 3/267:46 pmCAE - PTY
2 stops19h 46mAmerican Airlines
Deal found 2/19$467
This American Airlines deal was found by Cheapflights users on 2/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/151:20 pmPTY - CLT
1 stop9h 28mAmerican Airlines
Sun 5/188:19 pmCLT - PTY
1 stop16h 56mAmerican Airlines
Deal found 2/19$469
This Kiwi.com deal was found by Cheapflights users on 2/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/109:33 pmPTY - CLT
1 stop13h 41mMultiple Airlines
Tue 4/151:33 pmCLT - PTY
1 stop6h 56mMultiple Airlines
Deal found 2/20$474
This American Airlines deal was found by Cheapflights users on 2/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 3/251:05 pmPTY - MYR
2 stops19h 47mAmerican Airlines
Tue 5/67:54 pmMYR - PTY
2 stops17h 21mAmerican Airlines
Deal found 2/20$474
This United Airlines deal was found by Cheapflights users on 2/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 4/510:55 pmPTY - CHS
1 stop8h 55mUnited Airlines
Sat 4/125:10 pmCHS - PTY
1 stop24h 02mUnited Airlines
Deal found 2/18$479
This Delta deal was found by Cheapflights users on 2/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/32:23 pmPTY - GSP
1 stop8h 15mDelta
Tue 4/88:03 amGSP - PTY
1 stop5h 55mDelta
Deal found 2/20$492
This Delta deal was found by Cheapflights users on 2/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 3/252:20 pmPTY - CLT
1 stop8h 24mDelta
Tue 4/17:10 amCLT - PTY
1 stop6h 45mDelta
Deal found 2/20$503
This American Airlines deal was found by Cheapflights users on 2/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/33:50 pmPTY - GSP
2 stops19h 41mAmerican Airlines
Tue 4/86:20 pmGSP - PTY
2 stops18h 55mAmerican Airlines
Deal found 2/20$516
This United Airlines deal was found by Cheapflights users on 2/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 4/63:20 pmPTY - CLT
1 stop29h 39mUnited Airlines
Sun 4/136:13 amCLT - PTY
1 stop9h 01mUnited Airlines
Deal found 2/20$545

Find flights from Panama City to South Carolina within your budget

Customize your flight search to find flights from Panama City to South Carolina that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated February 20, 2025.

Fly from

Panama City

Fly to

South Carolina

Route

Depart

Return

Price

Panama CityCharleston

PTY - CHS

PTYCHS

Panama City Tocumen Intl

Sat 5/3

2:20 pm-11:58 pm

1 stop8h 38m

Charleston

Wed 5/14

5:30 am-12:51 pm

1 stop8h 21m

$436

Panama CityCharleston

PTY - CHS

PTYCHS

Panama City Tocumen Intl

Sat 5/3

1:05 pm-8:34 am

2 stops18h 29m

Charleston

Wed 5/14

7:00 am-12:15 pm

1 stop6h 15m

$450

Panama CityGreenville

PTY - GSP

PTYGSP

Panama City Tocumen Intl

Thu 3/20

3:40 pm-11:15 pm

1 stop30h 35m

Greenville

Thu 3/27

7:04 am-6:38 pm

1 stop12h 34m

$455

Panama CityColumbia

PTY - CAE

PTYCAE

Panama City Tocumen Intl

Wed 3/19

1:05 pm-9:54 am

2 stops19h 49m

Columbia Metropolitan

Wed 3/26

7:46 pm-2:32 pm

2 stops19h 46m

$467

Panama CityCharlotte

PTY - CLT

PTYCLT

Panama City Tocumen Intl

Thu 5/15

1:20 pm-11:48 pm

1 stop9h 28m

Charlotte Douglas

Sun 5/18

8:19 pm-12:15 pm

1 stop16h 56m

$469

Panama CityCharlotte

PTY - CLT

PTYCLT

Panama City Tocumen Intl

Thu 4/10

9:33 pm-12:14 pm

1 stop13h 41m

Charlotte Douglas

Tue 4/15

1:33 pm-7:29 pm

1 stop6h 56m

$474

Panama CityMyrtle Beach

PTY - MYR

PTYMYR

Panama City Tocumen Intl

Tue 3/25

1:05 pm-9:52 am

2 stops19h 47m

Myrtle Beach Intl

Tue 5/6

7:54 pm-12:15 pm

2 stops17h 21m

$474

Panama CityCharleston

PTY - CHS

PTYCHS

Panama City Tocumen Intl

Sat 4/5

10:55 pm-8:50 am

1 stop8h 55m

Charleston

Sat 4/12

5:10 pm-4:12 pm

1 stop24h 02m

$479

Panama CityGreenville

PTY - GSP

PTYGSP

Panama City Tocumen Intl

Thu 4/3

2:23 pm-11:38 pm

1 stop8h 15m

Greenville

Tue 4/8

8:03 am-12:58 pm

1 stop5h 55m

$492

Panama CityCharlotte

PTY - CLT

PTYCLT

Panama City Tocumen Intl

Tue 3/25

2:20 pm-11:44 pm

1 stop8h 24m

Charlotte Douglas

Tue 4/1

7:10 am-12:55 pm

1 stop6h 45m

$503

Flights are sorted by cheapest round-trip flights first.

Deals found on 2/19

Showing 1-10 of 25 results
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2
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Best time to book a flight from Panama City to South Carolina

Have a flexible travel schedule? Discover the best time to fly to South Carolina from Panama City with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Travel insights for flights from Panama City to South Carolina

Get recent, data-driven insights about flights from Panama City to South Carolina including ideal travel times, pricing trends, and more.

What is the cheapest time of day to fly from PTY to SC?

Find hourly flight availability from Panama City to South Carolina. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated February 20, 2025.

Regardless of the time of day you decide to fly, the ticket price will remain around the same. Book flights from Panama City to South Carolina as you normally would.

Rainfall in South Carolina by month

Plan your trip to South Carolina by taking into account the average rainfall totals by month.

In terms of precipitation, rainfall in South Carolina ranges from 3.0 - 6.5 inches per month. July is typically the wettest month, when rainfall can reach 6.5 in. November is typically the driest time to visit South Carolina when rainfall is around 3.0 in.

Temperature in South Carolina by month

Plan your trip to South Carolina by taking into account the average temperature totals by month.

If weather is an important factor for your trip to South Carolina, use this chart to help with planning. For those seeking warmer temperatures, July is the ideal time of year to visit, when temperatures reach an average of 78.8 F. Travelers looking to avoid the cold should look outside of January, when temperatures are typically at their lowest (around 44.6 F).

Reviews of airlines servicing South Carolina

Get insights into the airlines that provide service to South Carolina. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to South Carolina. Reviews last updated February 20, 2025.
Read reviews from past customers who have flown Delta, United Airlines and American Airlines from Panama City to South Carolina. In addition to providing an overall rating, users have also rated airlines in terms of entertainment options, comfort, food, crew/service, and boarding process.
Delta
8.0
Very good
8,220 reviews

Comfort

8.0

Overall

8.0

Crew

8.5

Food

7.3

Boarding

8.2

Entertainment

7.9

Reviews

1 / 20

10.0
Excellent

Aaron,Oct 2024

TUS - LAX

Delta has consistently been the best U.S. airline for my travels and this flight was no exception

Delta
8.0
Very good
8,220 reviews
Delta
8.0
Very good
8,220 reviews

Comfort

8.0

Overall

8.0

Crew

8.5

Food

7.3

Boarding

8.2

Entertainment

7.9

Reviews

1 / 20

10.0
Excellent

Aaron,Oct 2024

TUS - LAX

Delta has consistently been the best U.S. airline for my travels and this flight was no exception

United Airlines
7.4
Good
8,766 reviews
Delta
8.0
Very good
8,220 reviews

Comfort

8.0

Overall

8.0

Crew

8.5

Food

7.3

Boarding

8.2

Entertainment

7.9

Reviews

1 / 20

10.0
Excellent

Aaron,Oct 2024

TUS - LAX

Delta has consistently been the best U.S. airline for my travels and this flight was no exception

American Airlines
7.2
Good
10,000 reviews
Delta
8.0
Very good
8,220 reviews

Comfort

8.0

Overall

8.0

Crew

8.5

Food

7.3

Boarding

8.2

Entertainment

7.9

Reviews

1 / 20

10.0
Excellent

Aaron,Oct 2024

TUS - LAX

Delta has consistently been the best U.S. airline for my travels and this flight was no exception

Avianca
6.8
Okay
2,435 reviews
Delta
8.0
Very good
8,220 reviews

Comfort

8.0

Overall

8.0

Crew

8.5

Food

7.3

Boarding

8.2

Entertainment

7.9

Reviews

1 / 20

10.0
Excellent

Aaron,Oct 2024

TUS - LAX

Delta has consistently been the best U.S. airline for my travels and this flight was no exception

Related info for your journey

Find useful and relevant information for your journey from Panama City to South Carolina. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly from for flights from Panama City to South Carolina?

    Panama City Tocumen Intl (PTY) is the airport you will fly out of if you book a flight from Panama City to South Carolina. It is only a 11.4 mi journey to Tocumen Intl (PTY) from Panama City’s city center.

  • What are the cheapest airlines to fly from Panama City to South Carolina one-way?

    The cheapest airline one-way is United Airlines, with whom users have recently found tickets for as low as $276. However, be on the lookout for offers from Delta and American Airlines, as they are both options that can get you from Panama City to South Carolina for a low price.

  • What are the most popular routes from Panama City to South Carolina?

    The most popular flight routes from Panama City to South Carolina are Panama City Tocumen Intl - Charleston, Panama City Tocumen Intl - Charlotte Douglas and Panama City Tocumen Intl - Columbia Metropolitan.

  • Can I find deals for flights from Panama City to South Carolina that include hotel bookings?

    Yes. In addition to deals on Panama City to South Carolina flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Panama City to South Carolina?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Panama City to South Carolina.

  • Can I find deals for business class flights from Panama City to South Carolina?

    Yes. Cheapflights offers flight deals from Panama City to South Carolina by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Panama City to South Carolina?

    Currently, August is the cheapest month in which you can book a flight from Panama City to South Carolina (average of $217). Flying from Panama City to South Carolina in March is currently the most expensive (average of $335). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

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Alternative routes for Panama City to South Carolina

See prices for flight routes from nearby airports that may be better suited for you.
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