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South Carolina

$229+ Cheap flights from Panama to South Carolina

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 2/9. Fares are subject to change and may not be available on all flights or dates of travel.
PTY — CHS
Jan 26 — Feb 21
Sun 1/26
Sun 2/2
1 adult, Economy
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Cheap flight deals from Panama to South Carolina

Discover tips and strategies to find the most affordable flight options for your journey from Panama (PA0) to South Carolina (USSC). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated January 21, 2025.

Round-trip from

$436
(Delta)

One-way from

$229
(Avianca Connect)
From Panama to South Carolina
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One-way flight from Panama to South Carolina
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Find flight deals from Panama to South Carolina

Cheapest flights from Panama to South Carolina
Explore the most affordable flight options available from Panama to South Carolina. Find the lowest fares from popular airlines and budget airlines, with prices last updated on January 21, 2025.

This Delta deal was found by Cheapflights users on 1/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/32:02 pmPTY - CHS
1 stop8h 38mDelta
Wed 5/145:30 amCHS - PTY
1 stop8h 21mDelta
Deal found 1/21$436
This American Airlines deal was found by Cheapflights users on 1/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/31:15 pmPTY - CHS
2 stops18h 19mAmerican Airlines
Wed 5/145:35 amCHS - PTY
2 stops7h 55mAmerican Airlines
Deal found 1/21$450
This Avianca Connect deal was found by Cheapflights users on 1/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca Connect is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 1/235:25 pmPTY - CLT
2 stops18h 16mMultiple Airlines
Tue 2/46:10 amCLT - PTY
2 stops14h 50mMultiple Airlines
Deal found 1/21$467
This United Airlines deal was found by Cheapflights users on 1/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 3/2910:55 pmPTY - CLT
1 stop9h 18mUnited Airlines
Tue 5/65:00 pmCLT - PTY
1 stop22h 14mUnited Airlines
Deal found 1/21$470
This American Airlines deal was found by Cheapflights users on 1/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/31:05 pmPTY - GSP
2 stops19h 47mAmerican Airlines
Tue 4/86:00 amGSP - PTY
1 stop7h 15mAmerican Airlines
Deal found 1/20$472
This United Airlines deal was found by Cheapflights users on 1/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 2/144:40 pmPTY - CHS
1 stop23h 48mUnited Airlines
Thu 2/206:50 amCHS - PTY
1 stop12h 48mUnited Airlines
Deal found 1/21$500
This Mytrip deal was found by Cheapflights users on 1/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 1/243:19 amPTY - CHS
2 stops17h 31mMultiple Airlines
Mon 1/277:15 amCHS - PTY
2 stops17h 05mMultiple Airlines
Deal found 1/21$515
This American Airlines deal was found by Cheapflights users on 1/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 3/243:30 pmPTY - CAE
2 stops18h 17mAmerican Airlines
Mon 4/76:07 pmCAE - PTY
2 stops19h 08mAmerican Airlines
Deal found 1/21$537
This American Airlines deal was found by Cheapflights users on 1/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 5/181:50 pmPTY - CLT
1 stop19h 18mAmerican Airlines
Thu 6/59:43 pmCLT - PTY
1 stop15h 41mAmerican Airlines
Deal found 1/20$553
This Delta deal was found by Cheapflights users on 1/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 1/223:27 pmPTY - CLT
1 stop8h 14mDelta
Fri 2/710:05 amCLT - PTY
1 stop9h 56mDelta
Deal found 1/21$657
This Delta deal was found by Cheapflights users on 1/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 3/242:20 pmPTY - CAE
1 stop8h 18mDelta
Mon 4/75:40 amCAE - PTY
1 stop8h 18mDelta
Deal found 1/21$728
This American Airlines deal was found by Cheapflights users on 1/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 1/244:40 pmPTY - AGS
2 stops18h 02mAmerican Airlines
Sun 1/262:36 pmAGS - PTY
2 stops25h 13mAmerican Airlines
Deal found 1/20$738

Find flights from Panama to South Carolina within your budget

Customize your flight search to find flights from Panama to South Carolina that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated January 21, 2025.

Fly from

Any airport

Fly to

Any airport

Route

Depart

Return

Price

Panama CityCharlotte

PTY - CLT

PTYCLT

Panama City Tocumen Intl

Thu 2/20

5:25 pm-12:00 pm

2 stops18h 35m

Charlotte Douglas

Thu 2/27

6:40 am-9:00 pm

2 stops14h 20m

$435

Panama CityCharleston

PTY - CHS

PTYCHS

Panama City Tocumen Intl

Sat 5/3

2:02 pm-11:40 pm

1 stop8h 38m

Charleston

Wed 5/14

5:30 am-12:51 pm

1 stop8h 21m

$436

Panama CityCharleston

PTY - CHS

PTYCHS

Panama City Tocumen Intl

Sat 5/3

1:15 pm-8:34 am

2 stops18h 19m

Charleston

Wed 5/14

5:35 am-12:30 pm

2 stops7h 55m

$450

Panama CityCharlotte

PTY - CLT

PTYCLT

Panama City Tocumen Intl

Sat 3/29

10:55 pm-9:13 am

1 stop9h 18m

Charlotte Douglas

Tue 5/6

5:30 pm-2:14 pm

2 stops21h 44m

$470

Panama CityGreenville

PTY - GSP

PTYGSP

Panama City Tocumen Intl

Thu 4/3

3:50 pm-9:53 am

2 stops17h 03m

Greenville

Tue 4/8

7:40 pm-12:15 pm

2 stops17h 35m

$472

Panama CityCharleston

PTY - CHS

PTYCHS

Panama City Tocumen Intl

Fri 2/14

4:40 pm-4:28 pm

1 stop23h 48m

Charleston

Thu 2/20

6:50 am-7:38 pm

1 stop12h 48m

$500

Panama CityCharlotte

PTY - CLT

PTYCLT

Panama City Tocumen Intl

Thu 2/20

4:40 pm-8:16 am

1 stop15h 36m

Charlotte Douglas

Thu 2/27

9:10 pm-1:30 pm

1 stop16h 20m

$522

Panama CityColumbia

PTY - CAE

PTYCAE

Panama City Tocumen Intl

Mon 3/24

3:30 pm-10:47 am

2 stops18h 17m

Columbia Metropolitan

Mon 4/7

6:07 pm-12:15 pm

2 stops19h 08m

$537

Panama CityColumbia

PTY - CAE

PTYCAE

Panama City Tocumen Intl

Mon 3/24

2:20 pm-11:38 pm

1 stop8h 18m

Columbia Metropolitan

Mon 4/7

5:40 am-12:58 pm

1 stop8h 18m

$728

Panama CityCharlotte

PTY - CLT

PTYCLT

Panama City Tocumen Intl

Fri 3/28

3:19 am-9:46 am

2 stops29h 27m

Charlotte Douglas

Tue 5/6

10:24 am-10:10 am

2 stops24h 46m

$967

Flights are sorted by cheapest round-trip flights first.

Deals found on 1/20

Showing 1-10 of 14 results
1
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Best time to book a flight from Panama to South Carolina

Have a flexible travel schedule? Discover the best time to fly to South Carolina from Panama with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Travel insights for flights from Panama to South Carolina

Get recent, data-driven insights about flights from Panama to South Carolina including ideal travel times, pricing trends, and more.

What is the cheapest time of day to fly from PA to SC?

Find hourly flight availability from Panama to South Carolina. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated January 21, 2025.

Regardless of the time of day you decide to fly, the ticket price will remain around the same. Book flights from Panama to South Carolina as you normally would.

Rainfall in South Carolina by month

Plan your trip to South Carolina by taking into account the average rainfall totals by month.

In terms of precipitation, rainfall in South Carolina ranges from 3.0 - 6.5 inches per month. July is typically the wettest month, when rainfall can reach 6.5 in. November is typically the driest time to visit South Carolina when rainfall is around 3.0 in.

Temperature in South Carolina by month

Plan your trip to South Carolina by taking into account the average temperature totals by month.

If weather is an important factor for your trip to South Carolina, use this chart to help with planning. For those seeking warmer temperatures, July is the ideal time of year to visit, when temperatures reach an average of 78.8 F. Travelers looking to avoid the cold should look outside of January, when temperatures are typically at their lowest (around 44.6 F).

Reviews of airlines servicing South Carolina

Get insights into the airlines that provide service to South Carolina. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to South Carolina. Reviews last updated January 21, 2025.
Read reviews from past customers who have flown United Airlines, American Airlines and Delta from Panama to South Carolina. You can also see how each airline compares in terms of entertainment options, comfort, food, crew/service, and boarding process.
Delta
8.0
Very good
8,521 reviews

Comfort

8.0

Boarding

8.2

Crew

8.6

Entertainment

7.9

Overall

8.0

Food

7.3

Reviews

1 / 10

Delta has consistently been the best U.S. airline for my travels and this flight was no exception

Delta
8.0
Very good
8,521 reviews
Delta
8.0
Very good
8,521 reviews

Comfort

8.0

Boarding

8.2

Crew

8.6

Entertainment

7.9

Overall

8.0

Food

7.3

Reviews

1 / 10

Delta has consistently been the best U.S. airline for my travels and this flight was no exception

Copa Airlines
7.7
Good
1,662 reviews
Delta
8.0
Very good
8,521 reviews

Comfort

8.0

Boarding

8.2

Crew

8.6

Entertainment

7.9

Overall

8.0

Food

7.3

Reviews

1 / 10

Delta has consistently been the best U.S. airline for my travels and this flight was no exception

United Airlines
7.4
Good
8,985 reviews
Delta
8.0
Very good
8,521 reviews

Comfort

8.0

Boarding

8.2

Crew

8.6

Entertainment

7.9

Overall

8.0

Food

7.3

Reviews

1 / 10

Delta has consistently been the best U.S. airline for my travels and this flight was no exception

American Airlines
7.2
Good
10,000 reviews
Delta
8.0
Very good
8,521 reviews

Comfort

8.0

Boarding

8.2

Crew

8.6

Entertainment

7.9

Overall

8.0

Food

7.3

Reviews

1 / 10

Delta has consistently been the best U.S. airline for my travels and this flight was no exception

Avianca
6.9
Okay
2,579 reviews
Delta
8.0
Very good
8,521 reviews

Comfort

8.0

Boarding

8.2

Crew

8.6

Entertainment

7.9

Overall

8.0

Food

7.3

Reviews

1 / 10

Delta has consistently been the best U.S. airline for my travels and this flight was no exception

Related info for your journey

Find useful and relevant information for your journey from Panama to South Carolina. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What are the cheapest airlines to fly from Panama to South Carolina one-way?

    $279 is the cheapest one-way deal found within the past few days, from United Airlines. You may also be able to find cheap deals on Delta and Avianca, with prices starting from $322 and $542, respectively.

  • Can I find deals for flights from Panama to South Carolina that include hotel bookings?

    Yes. In addition to deals on Panama to South Carolina flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Panama to South Carolina?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Panama to South Carolina.

  • Can I find deals for business class flights from Panama to South Carolina?

    Yes. Cheapflights offers flight deals from Panama to South Carolina by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Panama to South Carolina?

    Currently, August is the cheapest month in which you can book a flight from Panama to South Carolina (average of $217). Flying from Panama to South Carolina in March is currently the most expensive (average of $335). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

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