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South Carolina

$265+ Cheap flights from Panama to South Carolina

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 5/2. Fares are subject to change and may not be available on all flights or dates of travel.
PTY — CHS
abr 7 — abr 141
seg 4/7
seg 4/14
1 adult, Economy
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Cheap flight deals from Panama to South Carolina

Keep the following information in mind while searching for Panama to South Carolina flight deals. Data was last updated abril 2, 2025.

Most accurate provider

FlightHub
3 stars

Most trusted provider

FlightHub
3 stars

Round-trip from

$406
(Delta)

One-way from

$265
(Delta)
Provider with most accurate pricing for Panama City Tocumen Intl-Myrtle Beach Intl flight deals.
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Provider most trusted by Cheapflights users for Panama City Tocumen Intl-Myrtle Beach Intl flights.
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From Panama to South Carolina
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One-way flight from Panama to South Carolina
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Find flight deals from Panama to South Carolina

Cheapest flights from Panama to South Carolina
Explore the most affordable flight options available from Panama to South Carolina. Find the lowest fares from popular airlines and budget airlines, with prices last updated on abril 2, 2025.

This Delta deal was found by Cheapflights users on 4/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
sáb 5/32:20 pmPTY - CHS
1 stop8h 38mDelta
qua 5/145:35 amCHS - PTY
1 stop8h 13mDelta
Deal found 4/1$406
This Avianca Connect deal was found by Cheapflights users on 4/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca Connect is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
dom 5/113:20 amPTY - CLT
2 stops15h 09mMultiple Airlines
qui 5/156:00 amCLT - PTY
2 stops16h 10mMultiple Airlines
Deal found 4/1$411
This American Airlines deal was found by Cheapflights users on 4/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
sáb 5/31:05 pmPTY - CHS
2 stops18h 29mAmerican Airlines
qua 5/145:26 pmCHS - PTY
2 stops19h 53mAmerican Airlines
Deal found 4/1$420
This United Airlines deal was found by Cheapflights users on 4/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
qui 4/247:55 amPTY - CLT
1 stop9h 12mUnited Airlines
qui 5/18:30 amCLT - PTY
1 stop11h 07mUnited Airlines
Deal found 4/1$428
This American Airlines deal was found by Cheapflights users on 3/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
ter 4/151:15 pmPTY - CAE
2 stops19h 38mAmerican Airlines
qui 5/157:45 pmCAE - PTY
2 stops17h 34mAmerican Airlines
Deal found 3/30$428
This American Airlines deal was found by Cheapflights users on 4/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
qui 5/151:20 pmPTY - CLT
1 stop7h 11mAmerican Airlines
dom 5/1810:27 pmCLT - PTY
1 stop14h 52mAmerican Airlines
Deal found 4/1$437
This United Airlines deal was found by Cheapflights users on 4/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
qui 4/37:55 amPTY - GSP
1 stop14h 34mUnited Airlines
ter 4/84:36 pmGSP - PTY
1 stop27h 01mUnited Airlines
Deal found 4/1$449
This American Airlines deal was found by Cheapflights users on 4/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
qui 8/143:16 pmPTY - MYR
2 stops23h 25mAmerican Airlines
seg 9/18:51 pmMYR - PTY
2 stops18h 24mAmerican Airlines
Deal found 4/1$482
This Avianca Connect deal was found by Cheapflights users on 4/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca Connect is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
qua 4/303:20 amPTY - MYR
2 stops16h 34mMultiple Airlines
qui 5/86:00 amMYR - PTY
2 stops19h 10mMultiple Airlines
Deal found 4/1$494
This Delta deal was found by Cheapflights users on 4/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
qua 8/132:12 pmPTY - MYR
1 stop18h 59mDelta
seg 9/16:45 pmMYR - PTY
1 stop19h 09mDelta
Deal found 4/1$537
This American Airlines deal was found by Cheapflights users on 4/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
qui 4/31:05 pmPTY - GSP
2 stops19h 47mAmerican Airlines
ter 4/86:00 amGSP - PTY
1 stop7h 15mAmerican Airlines
Deal found 4/1$573
This Mytrip deal was found by Cheapflights users on 4/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
ter 4/155:25 pmPTY - CHS
2 stops24h 10mMultiple Airlines
dom 4/2010:25 amCHS - PTY
3 stops38h 45mMultiple Airlines
Deal found 4/2$670

Cheapflights Fare Finder

Customize your flight search to find flights from Panama to South Carolina that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated abril 2, 2025.
Use the filters below to find and compare flights from Panama to South Carolina that are best for you.

Fly from

Panama

Fly to

South Carolina

Route

Depart

Return

Price

Panama CityCharleston

PTY - CHS

PTYCHS

Panama City Tocumen Intl

sáb 5/3

2:20 pm-11:58 pm

1 stop8h 38m

Charleston

qua 5/14

5:35 am-12:48 pm

1 stop8h 13m

$406

Panama CityCharlotte

PTY - CLT

PTYCLT

Panama City Tocumen Intl

dom 5/11

3:20 am-7:29 pm

2 stops15h 09m

Charlotte Douglas

qui 5/15

6:00 am-9:10 pm

2 stops16h 10m

$411

Panama CityCharleston

PTY - CHS

PTYCHS

Panama City Tocumen Intl

sáb 5/3

1:05 pm-8:34 am

2 stops18h 29m

Charleston

qua 5/14

5:26 pm-12:19 pm

2 stops19h 53m

$420

Panama CityCharlotte

PTY - CLT

PTYCLT

Panama City Tocumen Intl

qui 4/24

7:55 am-6:07 pm

1 stop9h 12m

Charlotte Douglas

qui 5/1

8:30 am-6:37 pm

1 stop11h 07m

$428

Panama CityColumbia

PTY - CAE

PTYCAE

Panama City Tocumen Intl

ter 4/15

1:15 pm-9:53 am

2 stops19h 38m

Columbia Metropolitan

qui 5/15

7:45 pm-12:19 pm

2 stops17h 34m

$428

Panama CityCharlotte

PTY - CLT

PTYCLT

Panama City Tocumen Intl

qui 5/15

1:20 pm-9:31 pm

1 stop7h 11m

Charlotte Douglas

dom 5/18

10:27 pm-12:19 pm

1 stop14h 52m

$437

Panama CityMyrtle Beach

PTY - MYR

PTYMYR

Panama City Tocumen Intl

qui 8/14

3:16 pm-3:41 pm

2 stops23h 25m

Myrtle Beach Intl

seg 9/1

8:51 pm-2:15 pm

2 stops18h 24m

$482

Panama CityMyrtle Beach

PTY - MYR

PTYMYR

Panama City Tocumen Intl

qua 4/30

3:20 am-8:54 pm

2 stops16h 34m

Myrtle Beach Intl

qui 5/8

6:00 am-12:10 am

2 stops19h 10m

$494

Panama CityMyrtle Beach

PTY - MYR

PTYMYR

Panama City Tocumen Intl

qua 8/13

2:12 pm-10:11 am

1 stop18h 59m

Myrtle Beach Intl

seg 9/1

6:45 pm-12:54 pm

1 stop19h 09m

$537

Panama CityCharleston

PTY - CHS

PTYCHS

Panama City Tocumen Intl

ter 4/15

5:25 pm-6:35 pm

2 stops24h 10m

Charleston

dom 4/20

10:25 am-12:10 am

3 stops38h 45m

$670

Flights are sorted by cheapest round-trip flights first.

Deals found on 4/1

Showing 1-10 of 25 results
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Best time to book a flight from Panama to South Carolina

Have a flexible travel schedule? Discover the best time to fly to South Carolina from Panama with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Panama to South Carolina

What is the cheapest month to book a flight from Panama to South Carolina?

Currently, August is the cheapest month in which you can book a flight from Panama to South Carolina (average of $217). Flying from Panama to South Carolina in March is currently the most expensive (average of $335). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from PA to SC?

Find hourly flight availability from Panama to South Carolina. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated abril 2, 2025.

Regardless of the time of day you decide to fly, the ticket price will remain around the same. Book flights from Panama to South Carolina as you normally would.

Rainfall in South Carolina by month

Plan your trip to South Carolina by taking into account the average rainfall totals by month.

In terms of precipitation, rainfall in South Carolina ranges from 3.0 - 6.5 inches per month. July is typically the wettest month, when rainfall can reach 6.5 in. November is typically the driest time to visit South Carolina when rainfall is around 3.0 in.

Temperature in South Carolina by month

Plan your trip to South Carolina by taking into account the average temperature totals by month.

If weather is an important factor for your trip to South Carolina, use this chart to help with planning. For those seeking warmer temperatures, July is the ideal time of year to visit, when temperatures reach an average of 78.8 F. Travelers looking to avoid the cold should look outside of January, when temperatures are typically at their lowest (around 44.6 F).

Reviews of airlines servicing South Carolina

Get insights into the airlines that provide service to South Carolina. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to South Carolina. Reviews last updated abril 2, 2025.
Read reviews from past customers who have flown Delta, Copa Airlines and United Airlines from Panama to South Carolina. You can also see how each airline compares in terms of entertainment options, comfort, food, crew/service, and boarding process.
Delta
8.0
Very good
7,897 reviews

Crew

8.5

Comfort

7.9

Food

7.3

Boarding

8.2

Entertainment

7.9

Overall

8.0

Reviews

1 / 20
10.0
Excellent

Aaron,Oct 2024

TUS - LAX

Delta has consistently been the best U.S. airline for my travels and this flight was no exception
Delta
8.0
Very good
7,897 reviews
Delta
8.0
Very good
7,897 reviews

Crew

8.5

Comfort

7.9

Food

7.3

Boarding

8.2

Entertainment

7.9

Overall

8.0

Reviews

1 / 20
10.0
Excellent

Aaron,Oct 2024

TUS - LAX

Delta has consistently been the best U.S. airline for my travels and this flight was no exception
Copa Airlines
7.6
Good
1,400 reviews
Delta
8.0
Very good
7,897 reviews

Crew

8.5

Comfort

7.9

Food

7.3

Boarding

8.2

Entertainment

7.9

Overall

8.0

Reviews

1 / 20
10.0
Excellent

Aaron,Oct 2024

TUS - LAX

Delta has consistently been the best U.S. airline for my travels and this flight was no exception
United Airlines
7.4
Good
8,616 reviews
Delta
8.0
Very good
7,897 reviews

Crew

8.5

Comfort

7.9

Food

7.3

Boarding

8.2

Entertainment

7.9

Overall

8.0

Reviews

1 / 20
10.0
Excellent

Aaron,Oct 2024

TUS - LAX

Delta has consistently been the best U.S. airline for my travels and this flight was no exception
American Airlines
7.2
Good
10,000 reviews
Delta
8.0
Very good
7,897 reviews

Crew

8.5

Comfort

7.9

Food

7.3

Boarding

8.2

Entertainment

7.9

Overall

8.0

Reviews

1 / 20
10.0
Excellent

Aaron,Oct 2024

TUS - LAX

Delta has consistently been the best U.S. airline for my travels and this flight was no exception
Avianca
6.7
Okay
2,301 reviews
Delta
8.0
Very good
7,897 reviews

Crew

8.5

Comfort

7.9

Food

7.3

Boarding

8.2

Entertainment

7.9

Overall

8.0

Reviews

1 / 20
10.0
Excellent

Aaron,Oct 2024

TUS - LAX

Delta has consistently been the best U.S. airline for my travels and this flight was no exception

Related info for your journey

Find useful and relevant information for your journey from Panama to South Carolina. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What are the cheapest airlines to fly from Panama to South Carolina one-way?

    $265 is the cheapest one-way deal found within the past few days, from Delta. You may also be able to find cheap deals on American Airlines and United Airlines, with prices starting from $274 and $278, respectively.

  • Can I find deals for flights from Panama to South Carolina that include hotel bookings?

    Yes. In addition to deals on Panama to South Carolina flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Panama to South Carolina?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Panama to South Carolina.

  • Can I find deals for business class flights from Panama to South Carolina?

    Yes. Cheapflights offers flight deals from Panama to South Carolina by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Panama to South Carolina?

    Currently, August is the cheapest month in which you can book a flight from Panama to South Carolina (average of $217). Flying from Panama to South Carolina in March is currently the most expensive (average of $335). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

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Alternative routes for Panama to South Carolina

See prices for flight routes from nearby airports that may be better suited for you.
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Top airline flying from Panama to South Carolina

Discover the top airline that operate flights from Panama to South Carolina. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated abril 2, 2025.
AirlineCheapestAverageFlexibilityOn-time
American AirlinesCheapest$423Average$501FlexibilityNo cancel feeOn-time71%

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