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South Carolina

$38+ Cheap flights from Ohio to South Carolina

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 5/24. Fares are subject to change and may not be available on all flights or dates of travel.
CVG — CHS
Apr 27 — May 41
Sun 4/27
Sun 5/4
1 adult, Economy
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Cheap flight deals from Ohio to South Carolina

Keep the following information in mind while searching for Ohio to South Carolina flight deals. Data was last updated April 22, 2025.

Most accurate provider

Mytrip
3 stars

Most trusted provider

Mytrip
3 stars

Round-trip from

$87
(Cheapflightsfares)

One-way from

$38
(Frontier)

Popular in

December

Cheapest in

May

Average price

$244

Good round-trip deal

$83 or less

Good one-way deal

$54 or less
Provider with most accurate pricing for Cleveland Hopkins Intl-Myrtle Beach Intl flight deals.
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Provider most trusted by Cheapflights users for Cleveland Hopkins Intl-Myrtle Beach Intl flights.
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From Ohio to South Carolina
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One-way flight from Ohio to South Carolina
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Highest demand for flights based on searches. 28% potential increase in price ($98 potential increase over avg. RT price).
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Cheapest flight prices on average. 5% potential price decrease ($13 potential savings vs. average RT price).
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Average for round-trip flights in April 2025
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Price to beat on a round-trip flight from Ohio to South Carolina.
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Price to beat on a one-way flight from Ohio to South Carolina.
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Find flight deals from Ohio to South Carolina

Cheapest flights from Ohio to South Carolina
Explore the most affordable flight options available from Ohio to South Carolina. Find the lowest fares from popular airlines and budget airlines, with prices last updated on April 22, 2025.

This Cheapflightsfares deal was found by Cheapflights users on 4/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/3112:41 pmCLE - MYR
Nonstop1h 45mSpirit Airlines
Sat 6/73:21 pmMYR - CLE
Nonstop1h 45mSpirit Airlines
Deal found 4/21$87
This Cheapflightsfares deal was found by Cheapflights users on 4/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/109:10 amCLE - MYR
Nonstop1h 42mMultiple Airlines
Wed 5/142:51 pmMYR - CLE
Nonstop1h 45mMultiple Airlines
Deal found 4/20$88
This Cheapflightsfares deal was found by Cheapflights users on 4/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/109:10 amCLE - MYR
Nonstop1h 42mFrontier
Sat 5/1711:52 amMYR - CLE
Nonstop1h 49mFrontier
Deal found 4/21$90
This Gotogate deal was found by Cheapflights users on 4/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Gotogate is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/316:30 amPIT - MYR
Nonstop1h 25mAllegiant Air
Mon 6/27:55 pmMYR - PIT
Nonstop1h 30mAllegiant Air
Deal found 4/22$107
This FlightHub deal was found by Cheapflights users on 4/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure FlightHub is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/1312:31 pmPIT - MYR
Nonstop1h 25mMultiple Airlines
Thu 5/154:51 pmMYR - PIT
Nonstop1h 31mMultiple Airlines
Deal found 4/21$126
This Cheapflightsfares deal was found by Cheapflights users on 4/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/318:40 amDTW - MYR
Nonstop1h 47mSpirit Airlines
Fri 6/61:45 pmMYR - DTW
Nonstop1h 55mSpirit Airlines
Deal found 4/21$129
This Cheapflightsfares deal was found by Cheapflights users on 4/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 6/197:01 pmPIT - MYR
Nonstop1h 21mSpirit Airlines
Tue 6/249:17 pmMYR - PIT
Nonstop1h 28mSpirit Airlines
Deal found 4/22$152
This Frontier deal was found by Cheapflights users on 4/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/155:45 amCVG - CLT
1 stop12h 11mFrontier
Sun 5/185:29 pmCLT - CVG
1 stop7h 11mFrontier
Deal found 4/22$160
This CheapOair deal was found by Cheapflights users on 4/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/219:17 pmCLE - CLT
1 stop23h 02mFrontier
Mon 5/268:03 pmCLT - CLE
Nonstop1h 43mFrontier
Deal found 4/22$170
This American Airlines deal was found by Cheapflights users on 4/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/205:30 amDTW - CLT
1 stop8h 11mAmerican Airlines
Tue 5/202:41 pmCLT - DTW
Nonstop1h 45mAmerican Airlines
Deal found 4/20$176
This CheapOair deal was found by Cheapflights users on 4/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/243:19 pmDTW - CLT
1 stop19h 22mFrontier
Wed 5/2811:31 amCLT - DTW
1 stop24h 15mFrontier
Deal found 4/22$181
This Booking.com deal was found by Cheapflights users on 4/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Booking.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 5/265:19 pmCLE - CLT
Nonstop1h 44mMultiple Airlines
Thu 5/298:50 amCLT - CLE
1 stop9h 25mMultiple Airlines
Deal found 4/22$183

Cheapflights Fare Finder

Customize your flight search to find flights from Ohio to South Carolina that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated April 22, 2025.
Use the filters below to find and compare flights from Ohio to South Carolina that are best for you.

Fly from

Ohio

Fly to

South Carolina

Route

Depart

Return

Price

ClevelandMyrtle Beach

CLE - MYR

CLEMYR

Cleveland Hopkins Intl

Sat 5/31

12:41 pm-2:26 pm

Nonstop1h 45m

Myrtle Beach Intl

Sat 6/7

3:21 pm-5:06 pm

Nonstop1h 45m

$87

ClevelandMyrtle Beach

CLE - MYR

CLEMYR

Cleveland Hopkins Intl

Sat 5/10

9:10 am-10:52 am

Nonstop1h 42m

Myrtle Beach Intl

Wed 5/14

2:51 pm-4:36 pm

Nonstop1h 45m

$88

ClevelandMyrtle Beach

CLE - MYR

CLEMYR

Cleveland Hopkins Intl

Sat 5/10

9:10 am-10:52 am

Nonstop1h 42m

Myrtle Beach Intl

Sat 5/17

11:52 am-1:41 pm

Nonstop1h 49m

$90

PittsburghMyrtle Beach

PIT - MYR

PITMYR

Pittsburgh

Sat 5/31

6:30 am-7:55 am

Nonstop1h 25m

Myrtle Beach Intl

Mon 6/2

7:55 pm-9:25 pm

Nonstop1h 30m

$107

PittsburghMyrtle Beach

PIT - MYR

PITMYR

Pittsburgh

Tue 5/13

12:31 pm-1:56 pm

Nonstop1h 25m

Myrtle Beach Intl

Thu 5/15

4:51 pm-6:22 pm

Nonstop1h 31m

$126

DetroitMyrtle Beach

DTW - MYR

DTWMYR

Detroit Metropolitan Wayne County

Sat 5/31

8:40 am-10:27 am

Nonstop1h 47m

Myrtle Beach Intl

Fri 6/6

1:45 pm-3:40 pm

Nonstop1h 55m

$129

PittsburghMyrtle Beach

PIT - MYR

PITMYR

Pittsburgh

Thu 6/19

7:01 pm-8:22 pm

Nonstop1h 21m

Myrtle Beach Intl

Tue 6/24

9:17 pm-10:45 pm

Nonstop1h 28m

$152

CincinnatiCharlotte

CVG - CLT

CVGCLT

Cincinnati Cinci./N. Kentucky

Thu 5/15

7:29 pm-6:54 am

1 stop11h 25m

Charlotte Douglas

Fri 5/16

4:21 pm-12:59 am

1 stop8h 38m

$160

ClevelandCharlotte

CLE - CLT

CLECLT

Cleveland Hopkins Intl

Wed 5/21

9:17 pm-8:19 pm

1 stop23h 02m

Charlotte Douglas

Mon 5/26

8:03 pm-9:46 pm

Nonstop1h 43m

$170

DetroitCharlotte

DTW - CLT

DTWCLT

Detroit Metropolitan Wayne County

Tue 5/20

5:30 am-1:41 pm

1 stop8h 11m

Charlotte Douglas

Tue 5/20

2:41 pm-4:26 pm

Nonstop1h 45m

$176

Flights are sorted by cheapest round-trip flights first.

Deals found on 4/21

Showing 1-10 of 60 results
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Best time to book a flight from Ohio to South Carolina

Have a flexible travel schedule? Discover the best time to fly to South Carolina from Ohio with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Ohio to South Carolina

What is the cheapest month to book a flight from Ohio to South Carolina?

Currently, August is the cheapest month in which you can book a flight from Ohio to South Carolina (average of $217). Flying from Ohio to South Carolina in March is currently the most expensive (average of $335). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from OH to SC?

Find hourly flight availability from Ohio to South Carolina. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated April 22, 2025.

When flying from Ohio to South Carolina, the time of day you decide to fly out makes little to no difference towards the overall price you’ll pay on tickets.

Rainfall in South Carolina by month

Plan your trip to South Carolina by taking into account the average rainfall totals by month.

In terms of precipitation, rainfall in South Carolina ranges from 3.0 - 6.5 inches per month. July is typically the wettest month, when rainfall can reach 6.5 in. November is typically the driest time to visit South Carolina when rainfall is around 3.0 in.

Temperature in South Carolina by month

Plan your trip to South Carolina by taking into account the average temperature totals by month.

If weather is an important factor for your trip to South Carolina, use this chart to help with planning. For those seeking warmer temperatures, July is the ideal time of year to visit, when temperatures reach an average of 78.8 F. Travelers looking to avoid the cold should look outside of January, when temperatures are typically at their lowest (around 44.6 F).

Reviews of airlines servicing South Carolina

Get insights into the airlines that provide service to South Carolina. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to South Carolina. Reviews last updated April 22, 2025.
Get a feel of what it's like to fly with Alaska Airlines, Southwest and Delta from Ohio to South Carolina by reading reviews from past customers. Users can see the overall rating for each airline as well as how each is rated in terms of entertainment options, comfort, food, crew/service, and boarding process.
Alaska Airlines
8.0
Very good
9,911 reviews

Crew

8.5

Boarding

8.2

Entertainment

7.1

Food

7.1

Overall

8.0

Comfort

7.9

Reviews

1 / 20
4.0
Okay

Anonymous,Apr 2025

LAS - STS

flight was delayed both ways even tho the weather was clear >
Alaska Airlines
8.0
Very good
9,911 reviews
Alaska Airlines
8.0
Very good
9,911 reviews

Crew

8.5

Boarding

8.2

Entertainment

7.1

Food

7.1

Overall

8.0

Comfort

7.9

Reviews

1 / 20
4.0
Okay

Anonymous,Apr 2025

LAS - STS

flight was delayed both ways even tho the weather was clear >
Southwest
8.0
Very good
4,287 reviews
Alaska Airlines
8.0
Very good
9,911 reviews

Crew

8.5

Boarding

8.2

Entertainment

7.1

Food

7.1

Overall

8.0

Comfort

7.9

Reviews

1 / 20
4.0
Okay

Anonymous,Apr 2025

LAS - STS

flight was delayed both ways even tho the weather was clear >
Delta
8.0
Very good
7,920 reviews
Alaska Airlines
8.0
Very good
9,911 reviews

Crew

8.5

Boarding

8.2

Entertainment

7.1

Food

7.1

Overall

8.0

Comfort

7.9

Reviews

1 / 20
4.0
Okay

Anonymous,Apr 2025

LAS - STS

flight was delayed both ways even tho the weather was clear >
Avelo Airlines
7.5
Good
Alaska Airlines
8.0
Very good
9,911 reviews

Crew

8.5

Boarding

8.2

Entertainment

7.1

Food

7.1

Overall

8.0

Comfort

7.9

Reviews

1 / 20
4.0
Okay

Anonymous,Apr 2025

LAS - STS

flight was delayed both ways even tho the weather was clear >
United Airlines
7.4
Good
8,683 reviews
Alaska Airlines
8.0
Very good
9,911 reviews

Crew

8.5

Boarding

8.2

Entertainment

7.1

Food

7.1

Overall

8.0

Comfort

7.9

Reviews

1 / 20
4.0
Okay

Anonymous,Apr 2025

LAS - STS

flight was delayed both ways even tho the weather was clear >

Related info for your journey

Find useful and relevant information for your journey from Ohio to South Carolina. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How popular is this Ohio to South Carolina flight route?

    This flight path from Ohio to South Carolina was viewed by 9 users in the past month. Keep an eye out for changes in search interest prior to high and low season.

  • What are the cheapest airlines to fly from Ohio to South Carolina one-way?

    The cheapest airline one-way is Frontier, with whom users have recently found tickets for as low as $38. However, be on the lookout for offers from Allegiant Air and Spirit Airlines, as they are both options that can get you from Ohio to South Carolina for a low price.

  • Can I find deals for flights from Ohio to South Carolina that include hotel bookings?

    Yes. In addition to deals on Ohio to South Carolina flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Ohio to South Carolina?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Ohio to South Carolina.

  • Can I find deals for business class flights from Ohio to South Carolina?

    Yes. Cheapflights offers flight deals from Ohio to South Carolina by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Ohio to South Carolina?

    Currently, August is the cheapest month in which you can book a flight from Ohio to South Carolina (average of $217). Flying from Ohio to South Carolina in March is currently the most expensive (average of $335). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

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Alternative routes for Ohio to South Carolina

See prices for flight routes from nearby airports that may be better suited for you.
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Top 8 airlines flying from Ohio to South Carolina

Discover the top 8 airlines that operate flights from Ohio to South Carolina. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated April 22, 2025.
AirlineCheapestAverageFlexibilityOn-time
Spirit AirlinesCheapest$53Average$164FlexibilityNo cancel feeOn-time65%
FrontierCheapest$58Average$125FlexibilityNo cancel feeOn-time62%
Breeze AirwaysCheapest$59Average$169FlexibilityNo cancel feeOn-timeN/A
Allegiant AirCheapest$74Average$146FlexibilityNo cancel feeOn-time88%
DeltaCheapest$175Average$328FlexibilityNo cancel feeOn-timeN/A
American AirlinesCheapest$176Average$379FlexibilityNo cancel feeOn-time71%
United AirlinesCheapest$180Average$348FlexibilityNo cancel feeOn-time69%
SouthwestCheapest$228Average$363FlexibilityNo cancel feeOn-time63%

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