HomeSearch by dateVacation packagesHotelsFlight dealsCar rentalTravel tips & news
South Carolina

$40+ Cheap flights from Ohio to South Carolina

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 3/28. Fares are subject to change and may not be available on all flights or dates of travel.
CLE — CHS
ene. 26 — feb. 21
dom. 1/26
dom. 2/2
1 adult, Economy
We work with more than 300 partners to bring you better travel deals

Find cheap flights from Ohio to South Carolina with Cheapflights

1. Tell us where you want to go
Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”
2. Select your favorite providers
We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.
3. Compare prices and book
Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.

Cheap flight deals from Ohio to South Carolina

Discover tips and strategies to find the most affordable flight options for your journey from Ohio (USOH) to South Carolina (USSC). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated enero 21, 2025.

Round-trip from

$80
(Cheapflightsfares)

One-way from

$40
(Cheapflightsfares)

Good round-trip deal

$78 or less

Good one-way deal

$57 or less
From Ohio to South Carolina
Search Deals
One-way flight from Ohio to South Carolina
Search Deals
Price to beat on a round-trip flight from Ohio to South Carolina.
Search Deals
Price to beat on a one-way flight from Ohio to South Carolina.
Search Deals

Find flight deals from Ohio to South Carolina

Cheapest flights from Ohio to South Carolina
Explore the most affordable flight options available from Ohio to South Carolina. Find the lowest fares from popular airlines and budget airlines, with prices last updated on enero 21, 2025.

This Cheapflightsfares deal was found by Cheapflights users on 1/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
sáb. 3/221:00 pmCLE - MYR
Nonstop1h 45mSpirit Airlines
mar. 3/259:30 pmMYR - CLE
Nonstop1h 45mSpirit Airlines
Deal found 1/21$80
This Cheapflightsfares deal was found by Cheapflights users on 1/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
jue. 5/110:21 amPIT - MYR
Nonstop1h 26mSpirit Airlines
jue. 5/88:00 amMYR - PIT
Nonstop1h 31mSpirit Airlines
Deal found 1/20$96
This Cheapflightsfares deal was found by Cheapflights users on 1/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
jue. 5/159:42 amCLE - MYR
Nonstop1h 42mFrontier
jue. 5/227:22 pmMYR - CLE
Nonstop1h 50mFrontier
Deal found 1/21$105
This Frontier deal was found by Cheapflights users on 1/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
sáb. 2/228:44 pmCLE - CLT
1 stop10h 24mFrontier
mié. 2/267:44 pmCLT - CLE
1 stop12h 02mFrontier
Deal found 1/21$109
This Kiwi.com deal was found by Cheapflights users on 1/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
dom. 5/251:34 pmPIT - MYR
Nonstop1h 27mAllegiant Air
dom. 6/19:50 pmMYR - PIT
Nonstop1h 31mAllegiant Air
Deal found 1/21$117
This Cheapflightsfares deal was found by Cheapflights users on 1/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
jue. 2/204:57 pmCLE - CLT
1 stop6h 44mSpirit Airlines
jue. 2/276:40 amCLT - CLE
1 stop8h 49mSpirit Airlines
Deal found 1/21$119
This Priceline deal was found by Cheapflights users on 1/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Priceline is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
sáb. 2/228:44 pmCLE - CLT
1 stop10h 24mMultiple Airlines
mar. 2/256:40 amCLT - CLE
1 stop8h 49mMultiple Airlines
Deal found 1/21$126
This Priceline deal was found by Cheapflights users on 1/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Priceline is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
sáb. 5/178:30 amCLE - MYR
1 stop8h 00mMultiple Airlines
sáb. 5/247:22 pmMYR - CLE
Nonstop1h 50mMultiple Airlines
Deal found 1/21$142
This Cheapflightsfares deal was found by Cheapflights users on 1/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mar. 4/16:00 amPIT - MYR
1 stop4h 28mMultiple Airlines
jue. 4/310:37 amMYR - PIT
1 stop4h 05mMultiple Airlines
Deal found 1/20$146
This eDestinos deal was found by Cheapflights users on 1/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure eDestinos is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mié. 2/195:45 amCLE - CHS
1 stop16h 53mMultiple Airlines
mié. 2/267:05 amCHS - CLE
1 stop9h 13mMultiple Airlines
Deal found 1/20$154
This Delta deal was found by Cheapflights users on 1/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mar. 2/1110:10 amDTW - MYR
Nonstop2h 01mDelta
sáb. 2/1512:56 pmMYR - DTW
Nonstop2h 02mDelta
Deal found 1/21$159
This CheapOair deal was found by Cheapflights users on 1/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
jue. 2/271:32 pmDTW - MYR
1 stop18h 31mSpirit Airlines
mié. 3/55:30 amMYR - DTW
1 stop10h 47mSpirit Airlines
Deal found 1/21$160

Find flights from Ohio to South Carolina within your budget

Customize your flight search to find flights from Ohio to South Carolina that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated enero 21, 2025.

Fly from

Any airport

Fly to

Any airport

Route

Depart

Return

Price

ClevelandMyrtle Beach

CLE - MYR

CLEMYR

Cleveland Hopkins Intl

sáb. 3/22

1:00 pm-2:45 pm

Nonstop1h 45m

Myrtle Beach Intl

mié. 3/26

9:30 pm-11:15 pm

Nonstop1h 45m

$80

PittsburghMyrtle Beach

PIT - MYR

PITMYR

Pittsburgh

jue. 5/1

10:21 am-11:47 am

Nonstop1h 26m

Myrtle Beach Intl

jue. 5/8

8:00 am-9:31 am

Nonstop1h 31m

$96

ClevelandMyrtle Beach

CLE - MYR

CLEMYR

Cleveland Hopkins Intl

jue. 5/15

9:42 am-11:24 am

Nonstop1h 42m

Myrtle Beach Intl

jue. 5/22

7:22 pm-9:12 pm

Nonstop1h 50m

$105

ClevelandCharlotte

CLE - CLT

CLECLT

Cleveland Hopkins Intl

sáb. 2/22

8:44 pm-7:08 am

1 stop10h 24m

Charlotte Douglas

mié. 2/26

7:44 pm-7:46 am

1 stop12h 02m

$109

PittsburghMyrtle Beach

PIT - MYR

PITMYR

Pittsburgh

dom. 5/25

1:34 pm-3:01 pm

Nonstop1h 27m

Myrtle Beach Intl

dom. 6/1

9:50 pm-11:21 pm

Nonstop1h 31m

$117

ClevelandCharlotte

CLE - CLT

CLECLT

Cleveland Hopkins Intl

jue. 2/20

4:57 pm-11:41 pm

1 stop6h 44m

Charlotte Douglas

jue. 2/27

6:40 am-3:29 pm

1 stop8h 49m

$119

ClevelandCharlotte

CLE - CLT

CLECLT

Cleveland Hopkins Intl

sáb. 2/22

8:44 pm-7:08 am

1 stop10h 24m

Charlotte Douglas

mar. 2/25

6:40 am-3:29 pm

1 stop8h 49m

$126

ClevelandMyrtle Beach

CLE - MYR

CLEMYR

Cleveland Hopkins Intl

sáb. 5/17

8:30 am-4:30 pm

1 stop8h 00m

Myrtle Beach Intl

sáb. 5/24

7:22 pm-9:12 pm

Nonstop1h 50m

$142

PittsburghMyrtle Beach

PIT - MYR

PITMYR

Pittsburgh

mar. 4/1

6:00 am-10:28 am

1 stop4h 28m

Myrtle Beach Intl

jue. 4/3

10:37 am-2:42 pm

1 stop4h 05m

$146

ClevelandCharleston

CLE - CHS

CLECHS

Cleveland Hopkins Intl

mié. 2/19

5:45 am-10:38 pm

1 stop16h 53m

Charleston

mié. 2/26

7:05 am-4:18 pm

1 stop9h 13m

$154

Flights are sorted by cheapest round-trip flights first.

Deals found on 1/20

Showing 1-10 of 60 results
1
2
3
...
6

Best time to book a flight from Ohio to South Carolina

Have a flexible travel schedule? Discover the best time to fly to South Carolina from Ohio with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Travel insights for flights from Ohio to South Carolina

Get recent, data-driven insights about flights from Ohio to South Carolina including ideal travel times, pricing trends, and more.

What is the cheapest month to book a flight from Ohio to South Carolina?

Currently, August is the cheapest month in which you can book a flight from Ohio to South Carolina (average of $217). Flying from Ohio to South Carolina in March is currently the most expensive (average of $335). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from OH to SC?

Find hourly flight availability from Ohio to South Carolina. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated enero 21, 2025.

When flying from Ohio to South Carolina, the time of day you decide to fly out makes little to no difference towards the overall price you’ll pay on tickets.

Rainfall in South Carolina by month

Plan your trip to South Carolina by taking into account the average rainfall totals by month.

In terms of precipitation, rainfall in South Carolina ranges from 3.0 - 6.5 inches per month. July is typically the wettest month, when rainfall can reach 6.5 in. November is typically the driest time to visit South Carolina when rainfall is around 3.0 in.

Temperature in South Carolina by month

Plan your trip to South Carolina by taking into account the average temperature totals by month.

If weather is an important factor for your trip to South Carolina, use this chart to help with planning. For those seeking warmer temperatures, July is the ideal time of year to visit, when temperatures reach an average of 78.8 F. Travelers looking to avoid the cold should look outside of January, when temperatures are typically at their lowest (around 44.6 F).

Reviews of airlines servicing South Carolina

Get insights into the airlines that provide service to South Carolina. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to South Carolina. Reviews last updated enero 21, 2025.
Get a feel of what it's like to fly with Spirit Airlines, American Airlines and Frontier from Ohio to South Carolina by reading reviews from past customers. Users can see the overall rating for each airline as well as how each is rated in terms of entertainment options, comfort, food, crew/service, and boarding process.
Southwest
8.1
Very good
4,662 reviews

Boarding

8.2

Food

7.2

Overall

8.1

Crew

8.7

Comfort

8.1

Entertainment

7.7

Reviews

1 / 10

We BARELY made the connection and when we got onboard we were treated like disobedient children who should have arrived earlier because we had to ask other passengers to move so we could sit with our kids. The flight attendants on the first flight were nice but the second one, they were snippy and fairly rude.

Southwest
8.1
Very good
4,662 reviews
Southwest
8.1
Very good
4,662 reviews

Boarding

8.2

Food

7.2

Overall

8.1

Crew

8.7

Comfort

8.1

Entertainment

7.7

Reviews

1 / 10

We BARELY made the connection and when we got onboard we were treated like disobedient children who should have arrived earlier because we had to ask other passengers to move so we could sit with our kids. The flight attendants on the first flight were nice but the second one, they were snippy and fairly rude.

Alaska Airlines
8.0
Very good
9,706 reviews
Southwest
8.1
Very good
4,662 reviews

Boarding

8.2

Food

7.2

Overall

8.1

Crew

8.7

Comfort

8.1

Entertainment

7.7

Reviews

1 / 10

We BARELY made the connection and when we got onboard we were treated like disobedient children who should have arrived earlier because we had to ask other passengers to move so we could sit with our kids. The flight attendants on the first flight were nice but the second one, they were snippy and fairly rude.

Delta
8.0
Very good
8,521 reviews
Southwest
8.1
Very good
4,662 reviews

Boarding

8.2

Food

7.2

Overall

8.1

Crew

8.7

Comfort

8.1

Entertainment

7.7

Reviews

1 / 10

We BARELY made the connection and when we got onboard we were treated like disobedient children who should have arrived earlier because we had to ask other passengers to move so we could sit with our kids. The flight attendants on the first flight were nice but the second one, they were snippy and fairly rude.

JetBlue
7.4
Good
3,201 reviews
Southwest
8.1
Very good
4,662 reviews

Boarding

8.2

Food

7.2

Overall

8.1

Crew

8.7

Comfort

8.1

Entertainment

7.7

Reviews

1 / 10

We BARELY made the connection and when we got onboard we were treated like disobedient children who should have arrived earlier because we had to ask other passengers to move so we could sit with our kids. The flight attendants on the first flight were nice but the second one, they were snippy and fairly rude.

United Airlines
7.4
Good
8,985 reviews
Southwest
8.1
Very good
4,662 reviews

Boarding

8.2

Food

7.2

Overall

8.1

Crew

8.7

Comfort

8.1

Entertainment

7.7

Reviews

1 / 10

We BARELY made the connection and when we got onboard we were treated like disobedient children who should have arrived earlier because we had to ask other passengers to move so we could sit with our kids. The flight attendants on the first flight were nice but the second one, they were snippy and fairly rude.

Related info for your journey

Find useful and relevant information for your journey from Ohio to South Carolina. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How popular is this Ohio to South Carolina flight route?

    This flight path from Ohio to South Carolina was viewed by 2 users in the past month. Keep an eye out for changes in search interest prior to high and low season.

  • What are the cheapest airlines to fly from Ohio to South Carolina one-way?

    The cheapest airline one-way is Spirit Airlines, with whom users have recently found tickets for as low as $40. However, be on the lookout for offers from Frontier and Delta, as they are both options that can get you from Ohio to South Carolina for a low price.

  • Can I find deals for flights from Ohio to South Carolina that include hotel bookings?

    Yes. In addition to deals on Ohio to South Carolina flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Ohio to South Carolina?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Ohio to South Carolina.

  • Can I find deals for business class flights from Ohio to South Carolina?

    Yes. Cheapflights offers flight deals from Ohio to South Carolina by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Ohio to South Carolina?

    Currently, August is the cheapest month in which you can book a flight from Ohio to South Carolina (average of $217). Flying from Ohio to South Carolina in March is currently the most expensive (average of $335). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Browse thousands of different options on Cheapflights for your next trip

Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.

Alternative routes for Ohio to South Carolina

See prices for flight routes from nearby airports that may be better suited for you.
John F Kennedy Intl to Miami flights
John F Kennedy Intl to Fort Lauderdale flights
Newark to Fort Lauderdale flights
LaGuardia to Fort Lauderdale flights
John F Kennedy Intl to Orlando flights
Newark to Miami flights
LaGuardia to Miami flights
Newark to Orlando flights
LaGuardia to Dallas/Fort Worth flights
Reagan-National to Miami flights
LaGuardia to Orlando flights
John F Kennedy Intl to West Palm Beach flights
John F Kennedy Intl to Las Vegas flights
John F Kennedy Intl to Los Angeles flights
Los Angeles to John F Kennedy Intl flights
Dulles Intl to Miami flights
Newark to Los Angeles flights
Boston to Fort Lauderdale flights
O'Hare Intl to Las Vegas flights
Los Angeles to Newark flights
O'Hare Intl to Orlando flights
O'Hare Intl to Sky Harbor Intl flights
Dallas/Fort Worth to Las Vegas flights
Boston to Orlando flights
Minneapolis to Sky Harbor Intl flights
Los Angeles to Dallas/Fort Worth flights
Dulles Intl to Orlando flights
John F Kennedy Intl to San Francisco flights
Dallas/Fort Worth to Orlando flights
Seattle to Sky Harbor Intl flights
Minneapolis to Las Vegas flights
John F Kennedy Intl to Dallas/Fort Worth flights
Philadelphia to Orlando flights
Dallas/Fort Worth to LaGuardia flights
O'Hare Intl to Fort Lauderdale flights
San Francisco to John F Kennedy Intl flights
John F Kennedy Intl to Sky Harbor Intl flights
Newark to Tampa flights
Detroit to Orlando flights
Boston to Miami flights
Los Angeles to Seattle flights
Dallas/Fort Worth to John F Kennedy Intl flights
John F Kennedy Intl to New Orleans flights
John F Kennedy Intl to Atlanta flights
O'Hare Intl to Miami flights
O'Hare Intl to John F Kennedy Intl flights
Denver to Las Vegas flights
O'Hare Intl to Dallas/Fort Worth flights
LaGuardia to New Orleans flights
Seattle to Las Vegas flights

Top 8 airlines flying from Ohio to South Carolina

Discover the top 8 airlines that operate flights from Ohio to South Carolina. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated enero 21, 2025.
AirlineCheapestAverageFlexibilityOn-time
FrontierCheapest$44Average$117FlexibilityNo cancel feeOn-time62%
Breeze AirwaysCheapest$58Average$178FlexibilityNo cancel feeOn-timeN/A
Spirit AirlinesCheapest$65Average$166FlexibilityNo cancel feeOn-time65%
Allegiant AirCheapest$74Average$155FlexibilityNo cancel feeOn-time88%
American AirlinesCheapest$174Average$379FlexibilityNo cancel feeOn-time71%
United AirlinesCheapest$184Average$364FlexibilityNo cancel feeOn-time69%
DeltaCheapest$188Average$343FlexibilityNo cancel feeOn-timeN/A
SouthwestCheapest$230Average$362FlexibilityNo cancel feeOn-time63%
100% Free
Cheapflights is completely free to use, so you can start saving the moment you arrive.
Book with Flexibility
Our users can plan ahead with confidence and find flights with no change fees
Travel Smart
Millions of people come to us for their flight needs every year. We help make travel planning easy by providing useful insights and data-driven graphs that can inform your decisions.