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$32+ Cheap flights from Ohio to South Carolina

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 3/12. Fares are subject to change and may not be available on all flights or dates of travel.
CLE — CHS
feb. 25 — mar. 41
mar. 2/25
mar. 3/4
1 adult, Economy
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Cheap flight deals from Ohio to South Carolina

Keep the following information in mind while searching for Ohio to South Carolina flight deals. Data was last updated febrero 20, 2025.

Most accurate provider

FlightHub
3 stars

Most trusted provider

FlightHub
3 stars

Round-trip from

$97
(Booking.com)

One-way from

$32
(Cheapflightsfares)

Popular in

December

Cheapest in

May

Average price

$328

Good round-trip deal

$98 or less

Good one-way deal

$49 or less
Provider with most accurate pricing for Cleveland Hopkins Intl-Myrtle Beach Intl flight deals.
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From Ohio to South Carolina
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One-way flight from Ohio to South Carolina
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Highest demand for flights based on searches. 26% potential increase in price ($90 potential increase over avg. RT price).
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Cheapest flight prices on average. 5% potential price decrease ($13 potential savings vs. average RT price).
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Average for round-trip flights in February 2025
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Price to beat on a round-trip flight from Ohio to South Carolina.
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Price to beat on a one-way flight from Ohio to South Carolina.
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Find flight deals from Ohio to South Carolina

Cheapest flights from Ohio to South Carolina
Explore the most affordable flight options available from Ohio to South Carolina. Find the lowest fares from popular airlines and budget airlines, with prices last updated on febrero 20, 2025.

This Booking.com deal was found by Cheapflights users on 2/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Booking.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
lun. 3/249:17 pmPIT - CHS
Nonstop1h 42mMultiple Airlines
jue. 3/2711:40 amCHS - PIT
1 stop5h 29mMultiple Airlines
Deal found 2/19$97
This Cheapflightsfares deal was found by Cheapflights users on 2/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
lun. 3/246:00 amPIT - CHS
1 stop7h 19mSpirit Airlines
jue. 3/2711:40 amCHS - PIT
1 stop5h 29mSpirit Airlines
Deal found 2/19$105
This FlightHub deal was found by Cheapflights users on 2/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure FlightHub is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
dom. 3/165:50 pmCLE - CHS
1 stop16h 03mSpirit Airlines
jue. 3/2011:40 amCHS - CLE
1 stop7h 54mSpirit Airlines
Deal found 2/19$111
This Breeze Airways deal was found by Cheapflights users on 2/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Breeze Airways is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
lun. 2/249:17 pmPIT - CHS
Nonstop1h 42mBreeze Airways
vie. 2/282:50 pmCHS - PIT
Nonstop1h 45mBreeze Airways
Deal found 2/20$118
This Cheapflightsfares deal was found by Cheapflights users on 2/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mié. 3/196:00 amPIT - MYR
1 stop4h 28mSpirit Airlines
mié. 3/266:41 pmMYR - PIT
1 stop5h 45mSpirit Airlines
Deal found 2/19$132
This Booking.com deal was found by Cheapflights users on 2/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Booking.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
sáb. 8/165:40 pmPIT - MYR
Nonstop1h 25mAllegiant Air
sáb. 8/232:15 pmMYR - PIT
Nonstop1h 30mAllegiant Air
Deal found 2/20$139
This Spirit deal was found by Cheapflights users on 2/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Spirit is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
dom. 5/253:07 pmDTW - MYR
Nonstop1h 52mSpirit Airlines
sáb. 5/315:00 amMYR - DTW
1 stop12h 49mSpirit Airlines
Deal found 2/20$151
This Mytrip deal was found by Cheapflights users on 2/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
vie. 4/41:08 pmCLE - CHS
2 stops27h 26mMultiple Airlines
lun. 4/77:00 amCHS - CLE
3 stops29h 13mMultiple Airlines
Deal found 2/20$184
This FlightHub deal was found by Cheapflights users on 2/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure FlightHub is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
vie. 3/71:00 pmDTW - CHS
1 stop25h 04mSpirit Airlines
jue. 3/132:59 pmCHS - DTW
1 stop19h 51mSpirit Airlines
Deal found 2/20$187
This Mytrip deal was found by Cheapflights users on 2/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
jue. 3/207:40 amPIT - MYR
3 stops24h 14mMultiple Airlines
jue. 3/279:19 amMYR - PIT
1 stop15h 13mMultiple Airlines
Deal found 2/20$193
This Mytrip deal was found by Cheapflights users on 2/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mar. 2/251:32 pmDTW - CHS
2 stops26h 51mMultiple Airlines
mar. 3/47:15 amCHS - DTW
2 stops15h 34mMultiple Airlines
Deal found 2/19$195
This Mytrip deal was found by Cheapflights users on 2/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
jue. 3/137:25 amDTW - CLT
2 stops15h 58mSpirit Airlines
dom. 3/1611:45 amCLT - DTW
2 stops33h 55mSpirit Airlines
Deal found 2/19$196

Find flights from Ohio to South Carolina within your budget

Customize your flight search to find flights from Ohio to South Carolina that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated febrero 20, 2025.

Fly from

Ohio

Fly to

South Carolina

Route

Depart

Return

Price

PittsburghCharleston

PIT - CHS

PITCHS

Pittsburgh

lun. 3/24

9:17 pm-10:59 pm

Nonstop1h 42m

Charleston

jue. 3/27

11:40 am-5:09 pm

1 stop5h 29m

$97

PittsburghCharleston

PIT - CHS

PITCHS

Pittsburgh

lun. 3/10

8:03 pm-2:04 pm

2 stops18h 01m

Charleston

mié. 3/12

10:48 am-6:17 pm

1 stop7h 29m

$101

PittsburghCharleston

PIT - CHS

PITCHS

Pittsburgh

sáb. 4/5

2:35 pm-4:18 pm

Nonstop1h 43m

Charleston

mar. 4/8

10:00 am-11:45 am

Nonstop1h 45m

$102

ClevelandCharleston

CLE - CHS

CLECHS

Cleveland Hopkins Intl

dom. 3/16

5:50 pm-9:53 am

1 stop16h 03m

Charleston

jue. 3/20

11:40 am-7:34 pm

1 stop7h 54m

$111

PittsburghMyrtle Beach

PIT - MYR

PITMYR

Pittsburgh

mié. 3/19

6:00 am-10:28 am

1 stop4h 28m

Myrtle Beach Intl

mié. 3/26

6:41 pm-12:26 am

1 stop5h 45m

$132

PittsburghMyrtle Beach

PIT - MYR

PITMYR

Pittsburgh

sáb. 8/16

5:40 pm-7:05 pm

Nonstop1h 25m

Myrtle Beach Intl

sáb. 8/23

2:15 pm-3:45 pm

Nonstop1h 30m

$139

DetroitMyrtle Beach

DTW - MYR

DTWMYR

Detroit Metropolitan Wayne County

jue. 3/27

11:53 am-1:45 pm

Nonstop1h 52m

Myrtle Beach Intl

vie. 4/4

8:15 am-10:16 am

Nonstop2h 01m

$151

ClevelandCharleston

CLE - CHS

CLECHS

Cleveland Hopkins Intl

vie. 4/4

1:08 pm-4:34 pm

2 stops27h 26m

Charleston

lun. 4/7

7:00 am-12:13 pm

3 stops29h 13m

$184

DetroitCharleston

DTW - CHS

DTWCHS

Detroit Metropolitan Wayne County

vie. 3/7

1:00 pm-2:04 pm

1 stop25h 04m

Charleston

jue. 3/13

2:59 pm-10:50 am

1 stop19h 51m

$187

PittsburghMyrtle Beach

PIT - MYR

PITMYR

Pittsburgh

jue. 3/20

7:40 am-7:54 am

3 stops24h 14m

Myrtle Beach Intl

jue. 3/27

9:19 am-12:32 am

1 stop15h 13m

$193

Flights are sorted by cheapest round-trip flights first.

Deals found on 2/20

Showing 1-10 of 60 results
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Best time to book a flight from Ohio to South Carolina

Have a flexible travel schedule? Discover the best time to fly to South Carolina from Ohio with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Travel insights for flights from Ohio to South Carolina

Get recent, data-driven insights about flights from Ohio to South Carolina including ideal travel times, pricing trends, and more.

What is the cheapest month to book a flight from Ohio to South Carolina?

Currently, August is the cheapest month in which you can book a flight from Ohio to South Carolina (average of $217). Flying from Ohio to South Carolina in March is currently the most expensive (average of $335). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from OH to SC?

Find hourly flight availability from Ohio to South Carolina. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated febrero 20, 2025.

When flying from Ohio to South Carolina, the time of day you decide to fly out makes little to no difference towards the overall price you’ll pay on tickets.

Rainfall in South Carolina by month

Plan your trip to South Carolina by taking into account the average rainfall totals by month.

In terms of precipitation, rainfall in South Carolina ranges from 3.0 - 6.5 inches per month. July is typically the wettest month, when rainfall can reach 6.5 in. November is typically the driest time to visit South Carolina when rainfall is around 3.0 in.

Temperature in South Carolina by month

Plan your trip to South Carolina by taking into account the average temperature totals by month.

If weather is an important factor for your trip to South Carolina, use this chart to help with planning. For those seeking warmer temperatures, July is the ideal time of year to visit, when temperatures reach an average of 78.8 F. Travelers looking to avoid the cold should look outside of January, when temperatures are typically at their lowest (around 44.6 F).

Reviews of airlines servicing South Carolina

Get insights into the airlines that provide service to South Carolina. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to South Carolina. Reviews last updated febrero 20, 2025.
Get a feel of what it's like to fly with Southwest, Breeze Airways and Alaska Airlines from Ohio to South Carolina by reading reviews from past customers. Users can see the overall rating for each airline as well as how each is rated in terms of entertainment options, comfort, food, crew/service, and boarding process.
Southwest
8.1
Very good
4,411 reviews

Food

7.1

Overall

8.1

Comfort

8.1

Crew

8.7

Entertainment

7.6

Boarding

8.2

Reviews

1 / 20

2.0
Mediocre

Anonymous,Feb 2025

MCO - STL

Cancelled at last minute, SWA unable to assist in formulating alternate plans. Wound up renting a car and driving 13 hours to beat bad weather forecast at home. Not SWA’s fault that there was significant bad weather across the country.

Southwest
8.1
Very good
4,411 reviews
Southwest
8.1
Very good
4,411 reviews

Food

7.1

Overall

8.1

Comfort

8.1

Crew

8.7

Entertainment

7.6

Boarding

8.2

Reviews

1 / 20

2.0
Mediocre

Anonymous,Feb 2025

MCO - STL

Cancelled at last minute, SWA unable to assist in formulating alternate plans. Wound up renting a car and driving 13 hours to beat bad weather forecast at home. Not SWA’s fault that there was significant bad weather across the country.

Breeze Airways
8.1
Very good
150 reviews
Southwest
8.1
Very good
4,411 reviews

Food

7.1

Overall

8.1

Comfort

8.1

Crew

8.7

Entertainment

7.6

Boarding

8.2

Reviews

1 / 20

2.0
Mediocre

Anonymous,Feb 2025

MCO - STL

Cancelled at last minute, SWA unable to assist in formulating alternate plans. Wound up renting a car and driving 13 hours to beat bad weather forecast at home. Not SWA’s fault that there was significant bad weather across the country.

Alaska Airlines
8.0
Very good
9,692 reviews
Southwest
8.1
Very good
4,411 reviews

Food

7.1

Overall

8.1

Comfort

8.1

Crew

8.7

Entertainment

7.6

Boarding

8.2

Reviews

1 / 20

2.0
Mediocre

Anonymous,Feb 2025

MCO - STL

Cancelled at last minute, SWA unable to assist in formulating alternate plans. Wound up renting a car and driving 13 hours to beat bad weather forecast at home. Not SWA’s fault that there was significant bad weather across the country.

Delta
8.0
Very good
8,220 reviews
Southwest
8.1
Very good
4,411 reviews

Food

7.1

Overall

8.1

Comfort

8.1

Crew

8.7

Entertainment

7.6

Boarding

8.2

Reviews

1 / 20

2.0
Mediocre

Anonymous,Feb 2025

MCO - STL

Cancelled at last minute, SWA unable to assist in formulating alternate plans. Wound up renting a car and driving 13 hours to beat bad weather forecast at home. Not SWA’s fault that there was significant bad weather across the country.

JetBlue
7.4
Good
3,070 reviews
Southwest
8.1
Very good
4,411 reviews

Food

7.1

Overall

8.1

Comfort

8.1

Crew

8.7

Entertainment

7.6

Boarding

8.2

Reviews

1 / 20

2.0
Mediocre

Anonymous,Feb 2025

MCO - STL

Cancelled at last minute, SWA unable to assist in formulating alternate plans. Wound up renting a car and driving 13 hours to beat bad weather forecast at home. Not SWA’s fault that there was significant bad weather across the country.

Related info for your journey

Find useful and relevant information for your journey from Ohio to South Carolina. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How popular is this Ohio to South Carolina flight route?

    This flight path from Ohio to South Carolina was viewed by 2 users in the past month. Keep an eye out for changes in search interest prior to high and low season.

  • What are the cheapest airlines to fly from Ohio to South Carolina one-way?

    The cheapest airline one-way is Spirit Airlines, with whom users have recently found tickets for as low as $32. However, be on the lookout for offers from Breeze Airways and Frontier, as they are both options that can get you from Ohio to South Carolina for a low price.

  • Can I find deals for flights from Ohio to South Carolina that include hotel bookings?

    Yes. In addition to deals on Ohio to South Carolina flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Ohio to South Carolina?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Ohio to South Carolina.

  • Can I find deals for business class flights from Ohio to South Carolina?

    Yes. Cheapflights offers flight deals from Ohio to South Carolina by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Ohio to South Carolina?

    Currently, August is the cheapest month in which you can book a flight from Ohio to South Carolina (average of $217). Flying from Ohio to South Carolina in March is currently the most expensive (average of $335). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Browse thousands of different options on Cheapflights for your next trip

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Alternative routes for Ohio to South Carolina

See prices for flight routes from nearby airports that may be better suited for you.
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Top 8 airlines flying from Ohio to South Carolina

Discover the top 8 airlines that operate flights from Ohio to South Carolina. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated febrero 20, 2025.
AirlineCheapestAverageFlexibilityOn-time
FrontierCheapest$45Average$123FlexibilityNo cancel feeOn-time62%
Spirit AirlinesCheapest$53Average$162FlexibilityNo cancel feeOn-time65%
Breeze AirwaysCheapest$60Average$173FlexibilityNo cancel feeOn-timeN/A
Allegiant AirCheapest$74Average$154FlexibilityNo cancel feeOn-time88%
American AirlinesCheapest$174Average$380FlexibilityNo cancel feeOn-time71%
United AirlinesCheapest$184Average$379FlexibilityNo cancel feeOn-time69%
DeltaCheapest$188Average$333FlexibilityNo cancel feeOn-timeN/A
SouthwestCheapest$222Average$365FlexibilityNo cancel feeOn-time63%
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