HomeSearch by dateVacation packagesHotelsFlight dealsCar rentalTravel tips & news
South Carolina

$194+ Cheap flights from Panama City, FL (ECP) to South Carolina

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 2/17. Fares are subject to change and may not be available on all flights or dates of travel.
ECP — CHS
Feb 4 — Feb 111
Tue 2/4
Tue 2/11
1 adult, Economy
We work with more than 300 partners to bring you better travel deals

Find cheap flights from Panama City to South Carolina with Cheapflights

1. Tell us where you want to go
Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”
2. Select your favorite providers
We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.
3. Compare prices and book
Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.

Cheap flight deals from Panama City to South Carolina

Discover tips and strategies to find the most affordable flight options for your journey from Panama City (ECP) to South Carolina (USSC). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated January 30, 2025.

Most accurate provider

FlightHub
3 stars

Most trusted provider

FlightHub
3 stars

Round-trip from

$217
(American Airlines)

One-way from

$194
(Delta)

Popular in

February

Cheapest in

August
Provider with most accurate pricing for Panama City NW Florida Beaches-Myrtle Beach Intl flight deals.
Search Deals
Provider most trusted by Cheapflights users for Panama City NW Florida Beaches-Myrtle Beach Intl flights.
Search Deals
From Panama City NW Florida Beaches to South Carolina
Search Deals
One-way flight from Panama City NW Florida Beaches to South Carolina
Search Deals
Highest demand for flights based on searches. 32% potential increase in price ($178 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 6% potential price decrease ($22 potential savings vs. average RT price).
Search Deals

Find flight deals from Panama City to South Carolina

Cheapest flights from Panama City to South Carolina
Explore the most affordable flight options available from Panama City to South Carolina. Find the lowest fares from popular airlines and budget airlines, with prices last updated on January 30, 2025.

This American Airlines deal was found by Cheapflights users on 1/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 2/272:36 pmECP - CHS
1 stop6h 26mAmerican Airlines
Tue 3/46:40 amCHS - ECP
1 stop4h 24mAmerican Airlines
Deal found 1/29$217
This Delta deal was found by Cheapflights users on 1/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 3/16:00 amECP - CHS
1 stop3h 07mDelta
Mon 3/35:35 amCHS - ECP
1 stop3h 50mDelta
Deal found 1/30$232
This Southwest deal was found by Cheapflights users on 1/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 3/710:10 amECP - CHS
2 stops10h 45mSouthwest
Mon 3/106:05 amCHS - ECP
1 stop8h 10mSouthwest
Deal found 1/29$237
This Delta deal was found by Cheapflights users on 1/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 3/67:20 amECP - MYR
1 stop5h 10mDelta
Mon 3/106:46 pmMYR - ECP
1 stop5h 18mDelta
Deal found 1/29$247
This Delta deal was found by Cheapflights users on 1/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/1311:15 amECP - GSP
1 stop3h 59mDelta
Tue 5/202:25 pmGSP - ECP
1 stop6h 10mDelta
Deal found 1/30$255
This Southwest deal was found by Cheapflights users on 1/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/136:50 amECP - GSP
2 stops7h 15mSouthwest
Tue 5/2010:55 amGSP - ECP
2 stops10h 00mSouthwest
Deal found 1/30$291
This Southwest deal was found by Cheapflights users on 1/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 2/285:10 pmECP - MYR
2 stops16h 10mSouthwest
Fri 3/75:25 pmMYR - ECP
1 stop7h 00mSouthwest
Deal found 1/29$341
This American Airlines deal was found by Cheapflights users on 1/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 3/62:40 pmECP - MYR
1 stop3h 57mAmerican Airlines
Mon 3/107:00 amMYR - ECP
2 stops14h 32mAmerican Airlines
Deal found 1/29$551

Find flights from Panama City to South Carolina within your budget

Customize your flight search to find flights from Panama City to South Carolina that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated January 30, 2025.

Fly from

Any airport

Fly to

Any airport

Route

Depart

Return

Price

Panama CityCharleston

ECP - CHS

ECPCHS

Panama City NW Florida Beaches

Thu 2/27

2:36 pm-10:02 pm

1 stop6h 26m

Charleston

Tue 3/4

6:40 am-10:04 am

1 stop4h 24m

$217

Panama CityCharleston

ECP - CHS

ECPCHS

Panama City NW Florida Beaches

Sat 3/1

6:00 am-10:07 am

1 stop3h 07m

Charleston

Mon 3/3

5:35 am-8:25 am

1 stop3h 50m

$232

Panama CityCharleston

ECP - CHS

ECPCHS

Panama City NW Florida Beaches

Fri 3/7

10:10 am-9:55 pm

2 stops10h 45m

Charleston

Mon 3/10

6:05 am-1:15 pm

1 stop8h 10m

$237

Panama CityMyrtle Beach

ECP - MYR

ECPMYR

Panama City NW Florida Beaches

Thu 3/6

7:20 am-1:30 pm

1 stop5h 10m

Myrtle Beach Intl

Mon 3/10

6:46 pm-11:04 pm

1 stop5h 18m

$247

Panama CityGreenville

ECP - GSP

ECPGSP

Panama City NW Florida Beaches

Tue 5/13

11:15 am-4:14 pm

1 stop3h 59m

Greenville

Tue 5/20

2:25 pm-7:35 pm

1 stop6h 10m

$255

Panama CityGreenville

ECP - GSP

ECPGSP

Panama City NW Florida Beaches

Tue 5/13

6:50 am-3:05 pm

2 stops7h 15m

Greenville

Tue 5/20

10:55 am-7:55 pm

2 stops10h 00m

$291

Panama CityMyrtle Beach

ECP - MYR

ECPMYR

Panama City NW Florida Beaches

Fri 2/28

5:10 pm-10:20 am

2 stops16h 10m

Myrtle Beach Intl

Fri 3/7

5:25 pm-11:25 pm

1 stop7h 00m

$341

Panama CityMyrtle Beach

ECP - MYR

ECPMYR

Panama City NW Florida Beaches

Thu 3/6

2:40 pm-7:37 pm

1 stop3h 57m

Myrtle Beach Intl

Mon 3/10

7:00 am-8:32 pm

2 stops14h 32m

$551

Panama CityMyrtle Beach

ECP - MYR

ECPMYR

Panama City NW Florida Beaches

Mon 2/17

6:00 am-10:15 am

1 stop3h 15m

$194

Panama CityMyrtle Beach

ECP - MYR

ECPMYR

Panama City NW Florida Beaches

Mon 2/17

6:30 am-2:12 pm

2 stops30h 42m

$509

Flights are sorted by cheapest round-trip flights first.

Deals found on 1/29

Best time to book a flight from Panama City to South Carolina

Have a flexible travel schedule? Discover the best time to fly to South Carolina from Panama City with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Travel insights for flights from Panama City to South Carolina

Get recent, data-driven insights about flights from Panama City to South Carolina including ideal travel times, pricing trends, and more.

What is the cheapest month to book a flight from Panama City, Florida to South Carolina?

Currently, August is the cheapest month in which you can book a flight from Panama City, Florida to South Carolina (average of $217). Flying from Panama City, Florida to South Carolina in March is currently the most expensive (average of $335). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from ECP to SC?

Find hourly flight availability from Panama City to South Carolina. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated January 30, 2025.

Regardless of the time of day you decide to fly, the ticket price will remain around the same. Book flights from Panama City, Florida to South Carolina as you normally would.

Rainfall in South Carolina by month

Plan your trip to South Carolina by taking into account the average rainfall totals by month.

In terms of precipitation, rainfall in South Carolina ranges from 3.0 - 6.5 inches per month. July is typically the wettest month, when rainfall can reach 6.5 in. November is typically the driest time to visit South Carolina when rainfall is around 3.0 in.

Temperature in South Carolina by month

Plan your trip to South Carolina by taking into account the average temperature totals by month.

If weather is an important factor for your trip to South Carolina, use this chart to help with planning. For those seeking warmer temperatures, July is the ideal time of year to visit, when temperatures reach an average of 78.8 F. Travelers looking to avoid the cold should look outside of January, when temperatures are typically at their lowest (around 44.6 F).

Reviews of airlines servicing South Carolina

Get insights into the airlines that provide service to South Carolina. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to South Carolina. Reviews last updated January 30, 2025.
Get a feel of what it's like to fly with Southwest, Delta and United Airlines from Panama City to South Carolina by reading reviews from past customers. You can also see how each airline compares in terms of entertainment options, comfort, food, crew/service, and boarding process.
Southwest
8.1
Very good
4,585 reviews

Boarding

8.2

Comfort

8.1

Entertainment

7.7

Crew

8.7

Overall

8.1

Food

7.1

Reviews

1 / 20

6.0
Good

Lauren,Dec 2024

MCI - DCA

We BARELY made the connection and when we got onboard we were treated like disobedient children who should have arrived earlier because we had to ask other passengers to move so we could sit with our kids. The flight attendants on the first flight were nice but the second one, they were snippy and fairly rude.

Southwest
8.1
Very good
4,585 reviews
Southwest
8.1
Very good
4,585 reviews

Boarding

8.2

Comfort

8.1

Entertainment

7.7

Crew

8.7

Overall

8.1

Food

7.1

Reviews

1 / 20

6.0
Good

Lauren,Dec 2024

MCI - DCA

We BARELY made the connection and when we got onboard we were treated like disobedient children who should have arrived earlier because we had to ask other passengers to move so we could sit with our kids. The flight attendants on the first flight were nice but the second one, they were snippy and fairly rude.

Delta
8.0
Very good
8,450 reviews
Southwest
8.1
Very good
4,585 reviews

Boarding

8.2

Comfort

8.1

Entertainment

7.7

Crew

8.7

Overall

8.1

Food

7.1

Reviews

1 / 20

6.0
Good

Lauren,Dec 2024

MCI - DCA

We BARELY made the connection and when we got onboard we were treated like disobedient children who should have arrived earlier because we had to ask other passengers to move so we could sit with our kids. The flight attendants on the first flight were nice but the second one, they were snippy and fairly rude.

United Airlines
7.4
Good
8,906 reviews
Southwest
8.1
Very good
4,585 reviews

Boarding

8.2

Comfort

8.1

Entertainment

7.7

Crew

8.7

Overall

8.1

Food

7.1

Reviews

1 / 20

6.0
Good

Lauren,Dec 2024

MCI - DCA

We BARELY made the connection and when we got onboard we were treated like disobedient children who should have arrived earlier because we had to ask other passengers to move so we could sit with our kids. The flight attendants on the first flight were nice but the second one, they were snippy and fairly rude.

American Airlines
7.2
Good
10,000 reviews
Southwest
8.1
Very good
4,585 reviews

Boarding

8.2

Comfort

8.1

Entertainment

7.7

Crew

8.7

Overall

8.1

Food

7.1

Reviews

1 / 20

6.0
Good

Lauren,Dec 2024

MCI - DCA

We BARELY made the connection and when we got onboard we were treated like disobedient children who should have arrived earlier because we had to ask other passengers to move so we could sit with our kids. The flight attendants on the first flight were nice but the second one, they were snippy and fairly rude.

Related info for your journey

Find useful and relevant information for your journey from Panama City to South Carolina. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly from for flights from Panama City to South Carolina?

    For a flight from Panama City to South Carolina, you will be flying from NW Florida Beaches. Panama City NW Florida Beaches (ECP) is just 16.0 mi from the center of the city.

  • What are the most popular routes from Panama City, Florida to South Carolina?

    Most travelers choose Panama City NW Florida Beaches - Charleston, Panama City NW Florida Beaches - Myrtle Beach Intl or Panama City NW Florida Beaches - Greenville when deciding on the best route from Panama City, Florida to South Carolina.

  • Can I find deals for flights from Panama City to South Carolina that include hotel bookings?

    Yes. In addition to deals on Panama City to South Carolina flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Panama City to South Carolina?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Panama City to South Carolina.

  • Can I find deals for business class flights from Panama City to South Carolina?

    Yes. Cheapflights offers flight deals from Panama City to South Carolina by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Panama City, Florida to South Carolina?

    Currently, August is the cheapest month in which you can book a flight from Panama City, Florida to South Carolina (average of $217). Flying from Panama City, Florida to South Carolina in March is currently the most expensive (average of $335). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Browse thousands of different options on Cheapflights for your next trip

Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.

Alternative routes for Panama City to South Carolina

See prices for flight routes from nearby airports that may be better suited for you.
Fort Lauderdale to LaGuardia flights
Miami to John F Kennedy Intl flights
Miami to LaGuardia flights
Fort Lauderdale to Newark flights
Orlando to Newark flights
Orlando to John F Kennedy Intl flights
Miami to Newark flights
Fort Lauderdale to John F Kennedy Intl flights
Orlando to LaGuardia flights
Fort Lauderdale to Las Vegas flights
Orlando to Las Vegas flights
Miami to Denver flights
Tampa to LaGuardia flights
Orlando to Denver flights
Tampa to Newark flights
Orlando to Dallas/Fort Worth flights
Tampa to John F Kennedy Intl flights
Miami to Las Vegas flights
Miami to Atlanta flights
Orlando to Los Angeles flights
Orlando to Seattle flights
Orlando to Dulles Intl flights
Miami to Los Angeles flights
West Palm Beach to John F Kennedy Intl flights
Fort Lauderdale to Boston flights
Tampa to Las Vegas flights
Fort Lauderdale to Denver flights
Tampa to Denver flights
Fort Lauderdale to Los Angeles flights
Orlando to Philadelphia flights
Fort Lauderdale to Hobby flights
Orlando to Boston flights
Tampa to Seattle flights
Tampa to Atlanta flights
Fort Lauderdale to Atlanta flights
Fort Lauderdale to New Orleans flights
Orlando to O'Hare Intl flights
West Palm Beach to LaGuardia flights
Orlando to Hobby flights
Tampa to Dulles Intl flights
Miami to Reagan-National flights
Orlando to Baltimore flights
Miami to Boston flights
Fort Lauderdale to Dallas/Fort Worth flights
Miami to Hobby flights
Orlando to Nashville flights
Tampa to Reagan-National flights
Fort Lauderdale to George Bush Intcntl flights
Fort Lauderdale to O'Hare Intl flights
West Palm Beach to Newark flights

Top 2 airlines flying from Panama City to South Carolina

Discover the top 2 airlines that operate flights from Panama City to South Carolina. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated January 30, 2025.
AirlineCheapestAverageFlexibilityOn-time
DeltaCheapest$206Average$476FlexibilityNo cancel feeOn-timeN/A
American AirlinesCheapest$225Average$436FlexibilityNo cancel feeOn-time71%
100% Free
Cheapflights is completely free to use, so you can start saving the moment you arrive.
Book with Flexibility
Our users can plan ahead with confidence and find flights with no change fees
Travel Smart
Millions of people come to us for their flight needs every year. We help make travel planning easy by providing useful insights and data-driven graphs that can inform your decisions.