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$247+ Cheap flights from Panama City, FL (ECP) to South Carolina

This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 3/24. Fares are subject to change and may not be available on all flights or dates of travel.
ECP — CHS
Mar 13 — Mar 201
Thu 3/13
Thu 3/20
1 adult, Economy
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Cheap flight deals from Panama City to South Carolina

Keep the following information in mind while searching for Panama City to South Carolina flight deals. Data was last updated March 8, 2025.

Most accurate provider

FlightHub
3 stars

Most trusted provider

FlightHub
3 stars

Round-trip from

$307
(Delta)

One-way from

$254
(Delta)

Popular in

October

Cheapest in

August

Average price

$538
Provider with most accurate pricing for Panama City NW Florida Beaches-Myrtle Beach Intl flight deals.
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Provider most trusted by Cheapflights users for Panama City NW Florida Beaches-Myrtle Beach Intl flights.
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From Panama City NW Florida Beaches to South Carolina
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One-way flight from Panama City NW Florida Beaches to South Carolina
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Highest demand for flights based on searches. 4% potential increase in price ($14 potential increase over avg. RT price).
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Cheapest flight prices on average. 6% potential price decrease ($23 potential savings vs. average RT price).
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Average for round-trip flights in March 2025
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Find flight deals from Panama City to South Carolina

Cheapest flights from Panama City to South Carolina
Explore the most affordable flight options available from Panama City to South Carolina. Find the lowest fares from popular airlines and budget airlines, with prices last updated on March 8, 2025.

This Delta deal was found by Cheapflights users on 3/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 3/246:51 pmECP - MYR
1 stop3h 58mDelta
Thu 3/276:46 pmMYR - ECP
1 stop5h 18mDelta
Deal found 3/7$247
This Delta deal was found by Cheapflights users on 3/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 7/126:00 amECP - CHS
1 stop5h 31mDelta
Mon 7/141:20 pmCHS - ECP
1 stop5h 31mDelta
Deal found 3/7$307
This American Airlines deal was found by Cheapflights users on 3/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/22:27 pmECP - CHS
1 stop4h 01mAmerican Airlines
Sun 5/45:10 amCHS - ECP
1 stop5h 18mAmerican Airlines
Deal found 3/7$322
This Southwest deal was found by Cheapflights users on 3/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 3/242:00 pmECP - MYR
1 stop4h 20mSouthwest
Thu 3/271:15 pmMYR - ECP
2 stops11h 10mSouthwest
Deal found 3/7$338
This Delta deal was found by Cheapflights users on 3/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 4/56:50 pmECP - GSP
1 stop3h 43mDelta
Fri 4/115:46 amGSP - ECP
1 stop3h 45mDelta
Deal found 3/7$342
This Southwest deal was found by Cheapflights users on 3/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 4/216:25 amECP - CHS
1 stop4h 30mSouthwest
Fri 4/255:25 pmCHS - ECP
1 stop5h 40mSouthwest
Deal found 3/6$379
This United Airlines deal was found by Cheapflights users on 3/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 4/56:15 amECP - GSP
2 stops15h 40mUnited Airlines
Fri 4/117:05 amGSP - ECP
1 stop14h 04mUnited Airlines
Deal found 3/7$641
This United Airlines deal was found by Cheapflights users on 3/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 4/134:58 pmECP - CHS
1 stop22h 16mUnited Airlines
Fri 4/184:45 pmCHS - ECP
2 stops20h 55mUnited Airlines
Deal found 3/7$734

Find flights from Panama City to South Carolina within your budget

Customize your flight search to find flights from Panama City to South Carolina that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated March 8, 2025.

Fly from

Panama City

Fly to

South Carolina

Route

Depart

Return

Price

Panama CityMyrtle Beach

ECP - MYR

ECPMYR

Panama City NW Florida Beaches

Mon 3/24

6:51 pm-11:49 pm

1 stop3h 58m

Myrtle Beach Intl

Thu 3/27

6:46 pm-11:04 pm

1 stop5h 18m

$247

Panama CityCharleston

ECP - CHS

ECPCHS

Panama City NW Florida Beaches

Sat 7/12

6:00 am-12:31 pm

1 stop5h 31m

Charleston

Mon 7/14

1:20 pm-5:51 pm

1 stop5h 31m

$307

Panama CityCharleston

ECP - CHS

ECPCHS

Panama City NW Florida Beaches

Fri 5/2

2:27 pm-7:28 pm

1 stop4h 01m

Charleston

Sun 5/4

5:10 am-9:28 am

1 stop5h 18m

$322

Panama CityMyrtle Beach

ECP - MYR

ECPMYR

Panama City NW Florida Beaches

Mon 3/24

2:00 pm-7:20 pm

1 stop4h 20m

Myrtle Beach Intl

Thu 3/27

1:15 pm-11:25 pm

2 stops11h 10m

$338

Panama CityGreenville

ECP - GSP

ECPGSP

Panama City NW Florida Beaches

Sat 4/5

6:50 pm-11:33 pm

1 stop3h 43m

Greenville

Fri 4/11

5:46 am-8:31 am

1 stop3h 45m

$342

Panama CityCharleston

ECP - CHS

ECPCHS

Panama City NW Florida Beaches

Mon 4/21

6:25 am-11:55 am

1 stop4h 30m

Charleston

Fri 4/25

5:25 pm-10:05 pm

1 stop5h 40m

$379

Panama CityGreenville

ECP - GSP

ECPGSP

Panama City NW Florida Beaches

Sat 4/5

6:15 am-10:55 pm

2 stops15h 40m

Greenville

Fri 4/11

7:05 am-8:09 pm

1 stop14h 04m

$641

Panama CityCharleston

ECP - CHS

ECPCHS

Panama City NW Florida Beaches

Sun 4/13

4:58 pm-4:14 pm

1 stop22h 16m

Charleston

Fri 4/18

4:45 pm-12:40 pm

2 stops20h 55m

$734

Panama CityMyrtle Beach

ECP - MYR

ECPMYR

Panama City NW Florida Beaches

Thu 3/13

7:25 am-1:23 pm

1 stop4h 58m

$254

Panama CityMyrtle Beach

ECP - MYR

ECPMYR

Panama City NW Florida Beaches

Thu 3/13

7:00 am-7:20 pm

2 stops11h 20m

$259

Flights are sorted by cheapest round-trip flights first.

Deals found on 3/6

Showing 1-10 of 15 results
1
2

Best time to book a flight from Panama City to South Carolina

Have a flexible travel schedule? Discover the best time to fly to South Carolina from Panama City with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Travel insights for flights from Panama City to South Carolina

Get recent, data-driven insights about flights from Panama City to South Carolina including ideal travel times, pricing trends, and more.

What is the cheapest month to book a flight from Panama City, Florida to South Carolina?

Currently, August is the cheapest month in which you can book a flight from Panama City, Florida to South Carolina (average of $217). Flying from Panama City, Florida to South Carolina in March is currently the most expensive (average of $335). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from ECP to SC?

Find hourly flight availability from Panama City to South Carolina. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated March 8, 2025.

Regardless of the time of day you decide to fly, the ticket price will remain around the same. Book flights from Panama City, Florida to South Carolina as you normally would.

Rainfall in South Carolina by month

Plan your trip to South Carolina by taking into account the average rainfall totals by month.

In terms of precipitation, rainfall in South Carolina ranges from 3.0 - 6.5 inches per month. July is typically the wettest month, when rainfall can reach 6.5 in. November is typically the driest time to visit South Carolina when rainfall is around 3.0 in.

Temperature in South Carolina by month

Plan your trip to South Carolina by taking into account the average temperature totals by month.

If weather is an important factor for your trip to South Carolina, use this chart to help with planning. For those seeking warmer temperatures, July is the ideal time of year to visit, when temperatures reach an average of 78.8 F. Travelers looking to avoid the cold should look outside of January, when temperatures are typically at their lowest (around 44.6 F).

Reviews of airlines servicing South Carolina

Get insights into the airlines that provide service to South Carolina. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to South Carolina. Reviews last updated March 8, 2025.
Get a feel of what it's like to fly with Southwest, Delta and United Airlines from Panama City to South Carolina by reading reviews from past customers. You can also see how each airline compares in terms of entertainment options, comfort, food, crew/service, and boarding process.
Southwest
8.1
Very good
4,314 reviews

Entertainment

7.6

Overall

8.1

Food

7.1

Boarding

8.2

Comfort

8.1

Crew

8.7

Reviews

1 / 20

8.0
Excellent

Ila,Mar 2025

HOU - DAL

Our original flight was delayed. We were able to change our flight and got home at close to the same time. Looking forward to when you have assigned seating.

Southwest
8.1
Very good
4,314 reviews
Southwest
8.1
Very good
4,314 reviews

Entertainment

7.6

Overall

8.1

Food

7.1

Boarding

8.2

Comfort

8.1

Crew

8.7

Reviews

1 / 20

8.0
Excellent

Ila,Mar 2025

HOU - DAL

Our original flight was delayed. We were able to change our flight and got home at close to the same time. Looking forward to when you have assigned seating.

Delta
8.0
Very good
8,024 reviews
Southwest
8.1
Very good
4,314 reviews

Entertainment

7.6

Overall

8.1

Food

7.1

Boarding

8.2

Comfort

8.1

Crew

8.7

Reviews

1 / 20

8.0
Excellent

Ila,Mar 2025

HOU - DAL

Our original flight was delayed. We were able to change our flight and got home at close to the same time. Looking forward to when you have assigned seating.

United Airlines
7.4
Good
8,649 reviews
Southwest
8.1
Very good
4,314 reviews

Entertainment

7.6

Overall

8.1

Food

7.1

Boarding

8.2

Comfort

8.1

Crew

8.7

Reviews

1 / 20

8.0
Excellent

Ila,Mar 2025

HOU - DAL

Our original flight was delayed. We were able to change our flight and got home at close to the same time. Looking forward to when you have assigned seating.

American Airlines
7.2
Good
10,000 reviews
Southwest
8.1
Very good
4,314 reviews

Entertainment

7.6

Overall

8.1

Food

7.1

Boarding

8.2

Comfort

8.1

Crew

8.7

Reviews

1 / 20

8.0
Excellent

Ila,Mar 2025

HOU - DAL

Our original flight was delayed. We were able to change our flight and got home at close to the same time. Looking forward to when you have assigned seating.

Related info for your journey

Find useful and relevant information for your journey from Panama City to South Carolina. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly from for flights from Panama City to South Carolina?

    For a flight from Panama City to South Carolina, you will be flying from NW Florida Beaches. Panama City NW Florida Beaches (ECP) is just 16.0 mi from the center of the city.

  • What are the cheapest airlines to fly from Panama City, Florida to South Carolina one-way?

    The cheapest airlines for a one-way flight from Panama City, Florida to South Carolina are Delta ($254), Southwest ($259), and American Airlines ($334).

  • What are the most popular routes from Panama City, Florida to South Carolina?

    Most travelers choose Panama City NW Florida Beaches - Charleston, Panama City NW Florida Beaches - Myrtle Beach Intl or Panama City NW Florida Beaches - Greenville when deciding on the best route from Panama City, Florida to South Carolina.

  • Can I find deals for flights from Panama City to South Carolina that include hotel bookings?

    Yes. In addition to deals on Panama City to South Carolina flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Panama City to South Carolina?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Panama City to South Carolina.

  • Can I find deals for business class flights from Panama City to South Carolina?

    Yes. Cheapflights offers flight deals from Panama City to South Carolina by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Panama City, Florida to South Carolina?

    Currently, August is the cheapest month in which you can book a flight from Panama City, Florida to South Carolina (average of $217). Flying from Panama City, Florida to South Carolina in March is currently the most expensive (average of $335). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

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Alternative routes for Panama City to South Carolina

See prices for flight routes from nearby airports that may be better suited for you.
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Top 2 airlines flying from Panama City to South Carolina

Discover the top 2 airlines that operate flights from Panama City to South Carolina. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated March 8, 2025.
AirlineCheapestAverageFlexibilityOn-time
DeltaCheapest$206Average$479FlexibilityNo cancel feeOn-timeN/A
American AirlinesCheapest$225Average$436FlexibilityNo cancel feeOn-time71%
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