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South Carolina

$115+ Cheap flights from Panama City, FL (ECP) to South Carolina

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 5/20. Fares are subject to change and may not be available on all flights or dates of travel.
ECP — CHS
Apr 13 — Apr 201
Sun 4/13
Sun 4/20
1 adult, Economy
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Cheap flight deals from Panama City to South Carolina

Keep the following information in mind while searching for Panama City to South Carolina flight deals. Data was last updated April 8, 2025.

Most accurate provider

FlightHub
3 stars

Most trusted provider

FlightHub
3 stars

Round-trip from

$281
(Delta)

One-way from

$219
(Southwest)

Popular in

March

Cheapest in

August

Average price

$357
Provider with most accurate pricing for Panama City NW Florida Beaches-Myrtle Beach Intl flight deals.
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Provider most trusted by Cheapflights users for Panama City NW Florida Beaches-Myrtle Beach Intl flights.
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From Panama City NW Florida Beaches to South Carolina
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One-way flight from Panama City NW Florida Beaches to South Carolina
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Highest demand for flights based on searches. 23% potential increase in price ($104 potential increase over avg. RT price).
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Cheapest flight prices on average. 11% potential price decrease ($36 potential savings vs. average RT price).
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Average for round-trip flights in April 2025
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Find flight deals from Panama City to South Carolina

Cheapest flights from Panama City to South Carolina
Explore the most affordable flight options available from Panama City to South Carolina. Find the lowest fares from popular airlines and budget airlines, with prices last updated on April 8, 2025.

This Delta deal was found by Cheapflights users on 4/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 6/256:00 amECP - MYR
1 stop5h 29mDelta
Sun 6/296:00 amMYR - ECP
1 stop3h 30mDelta
Deal found 4/6$281
This Delta deal was found by Cheapflights users on 4/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 7/286:00 amECP - GSP
1 stop4h 04mDelta
Mon 7/283:42 pmGSP - ECP
1 stop3h 09mDelta
Deal found 4/7$307
This Delta deal was found by Cheapflights users on 4/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 7/122:50 pmECP - CHS
1 stop6h 18mDelta
Mon 7/145:20 amCHS - ECP
1 stop5h 53mDelta
Deal found 4/7$307
This American Airlines deal was found by Cheapflights users on 4/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 6/192:39 pmECP - CHS
2 stops8h 19mAmerican Airlines
Sat 6/218:30 pmCHS - ECP
1 stop4h 19mAmerican Airlines
Deal found 4/6$312
This Southwest deal was found by Cheapflights users on 4/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 6/256:50 amECP - MYR
1 stop3h 50mSouthwest
Sun 6/297:00 amMYR - ECP
2 stops10h 35mSouthwest
Deal found 4/6$356
This Southwest deal was found by Cheapflights users on 4/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 7/2112:35 pmECP - CHS
2 stops9h 45mSouthwest
Thu 7/2412:55 pmCHS - ECP
2 stops11h 05mSouthwest
Deal found 4/6$421
This American Airlines deal was found by Cheapflights users on 4/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 6/225:11 amECP - MYR
1 stop3h 28mAmerican Airlines
Sun 6/227:40 pmMYR - ECP
1 stop5h 09mAmerican Airlines
Deal found 4/7$472
This Southwest deal was found by Cheapflights users on 4/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 4/77:00 amECP - GSP
2 stops8h 35mSouthwest
Sun 4/1310:25 amGSP - ECP
1 stop6h 35mSouthwest
Deal found 4/6$592
This United Airlines deal was found by Cheapflights users on 4/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 4/224:58 pmECP - GSP
2 stops16h 11mUnited Airlines
Sat 4/266:41 amGSP - ECP
2 stops14h 28mUnited Airlines
Deal found 4/7$598
This United Airlines deal was found by Cheapflights users on 4/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 6/172:03 pmECP - MYR
1 stop23h 32mUnited Airlines
Sat 6/215:00 pmMYR - ECP
2 stops27h 15mUnited Airlines
Deal found 4/7$750
This United deal was found by Cheapflights users on 4/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 7/125:02 pmECP - CHS
2 stops16h 35mUnited Airlines
Mon 7/147:40 pmCHS - ECP
2 stops18h 43mUnited Airlines
Deal found 4/7$765
This American Airlines deal was found by Cheapflights users on 4/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 4/2710:13 amECP - GSP
2 stops7h 19mAmerican Airlines
Sun 4/277:40 pmGSP - ECP
1 stop15h 48mAmerican Airlines
Deal found 4/7$2,059

Cheapflights Fare Finder

Customize your flight search to find flights from Panama City to South Carolina that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated April 8, 2025.
Use the filters below to find and compare flights from Panama City to South Carolina that are best for you.

Fly from

Panama City

Fly to

South Carolina

Route

Depart

Return

Price

Panama CityMyrtle Beach

ECP - MYR

ECPMYR

Panama City NW Florida Beaches

Wed 6/25

6:00 am-12:29 pm

1 stop5h 29m

Myrtle Beach Intl

Sun 6/29

6:00 am-8:30 am

1 stop3h 30m

$281

Panama CityGreenville

ECP - GSP

ECPGSP

Panama City NW Florida Beaches

Mon 7/28

6:00 am-11:04 am

1 stop4h 04m

Greenville

Mon 7/28

3:42 pm-5:51 pm

1 stop3h 09m

$307

Panama CityCharleston

ECP - CHS

ECPCHS

Panama City NW Florida Beaches

Thu 6/19

2:47 pm-8:46 pm

1 stop4h 59m

Charleston

Sat 6/21

5:15 am-8:30 am

1 stop4h 15m

$307

Panama CityCharleston

ECP - CHS

ECPCHS

Panama City NW Florida Beaches

Thu 6/19

2:39 pm-11:58 pm

2 stops8h 19m

Charleston

Sat 6/21

8:30 pm-11:49 pm

1 stop4h 19m

$312

Panama CityMyrtle Beach

ECP - MYR

ECPMYR

Panama City NW Florida Beaches

Wed 6/25

6:50 am-11:40 am

1 stop3h 50m

Myrtle Beach Intl

Sun 6/29

7:00 am-4:35 pm

2 stops10h 35m

$356

Panama CityMyrtle Beach

ECP - MYR

ECPMYR

Panama City NW Florida Beaches

Sun 6/22

5:11 am-9:39 am

1 stop3h 28m

Myrtle Beach Intl

Sun 6/22

7:40 pm-11:49 pm

1 stop5h 09m

$472

Panama CityCharleston

ECP - CHS

ECPCHS

Panama City NW Florida Beaches

Thu 6/19

12:35 pm-10:25 pm

2 stops8h 50m

Charleston

Sat 6/21

6:30 am-5:50 pm

2 stops12h 20m

$482

Panama CityGreenville

ECP - GSP

ECPGSP

Panama City NW Florida Beaches

Tue 4/22

4:58 pm-10:09 am

2 stops16h 11m

Greenville

Sat 4/26

6:41 am-8:09 pm

2 stops14h 28m

$598

Panama CityMyrtle Beach

ECP - MYR

ECPMYR

Panama City NW Florida Beaches

Tue 6/17

2:03 pm-2:35 pm

1 stop23h 32m

Myrtle Beach Intl

Sat 6/21

5:00 pm-7:15 pm

2 stops27h 15m

$750

Panama CityCharleston

ECP - CHS

ECPCHS

Panama City NW Florida Beaches

Sat 7/12

5:02 pm-10:37 am

2 stops16h 35m

Charleston

Mon 7/14

7:40 pm-1:23 pm

2 stops18h 43m

$765

Flights are sorted by cheapest round-trip flights first.

Deals found on 4/7

Showing 1-10 of 19 results
1
2

Best time to book a flight from Panama City to South Carolina

Have a flexible travel schedule? Discover the best time to fly to South Carolina from Panama City with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Panama City to South Carolina

What is the cheapest month to book a flight from Panama City, Florida to South Carolina?

Currently, August is the cheapest month in which you can book a flight from Panama City, Florida to South Carolina (average of $217). Flying from Panama City, Florida to South Carolina in March is currently the most expensive (average of $335). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from ECP to SC?

Find hourly flight availability from Panama City to South Carolina. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated April 8, 2025.

Regardless of the time of day you decide to fly, the ticket price will remain around the same. Book flights from Panama City, Florida to South Carolina as you normally would.

Rainfall in South Carolina by month

Plan your trip to South Carolina by taking into account the average rainfall totals by month.

In terms of precipitation, rainfall in South Carolina ranges from 3.0 - 6.5 inches per month. July is typically the wettest month, when rainfall can reach 6.5 in. November is typically the driest time to visit South Carolina when rainfall is around 3.0 in.

Temperature in South Carolina by month

Plan your trip to South Carolina by taking into account the average temperature totals by month.

If weather is an important factor for your trip to South Carolina, use this chart to help with planning. For those seeking warmer temperatures, July is the ideal time of year to visit, when temperatures reach an average of 78.8 F. Travelers looking to avoid the cold should look outside of January, when temperatures are typically at their lowest (around 44.6 F).

Reviews of airlines servicing South Carolina

Get insights into the airlines that provide service to South Carolina. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to South Carolina. Reviews last updated April 8, 2025.
Get a feel of what it's like to fly with Southwest, Delta and United Airlines from Panama City to South Carolina by reading reviews from past customers. You can also see how each airline compares in terms of entertainment options, comfort, food, crew/service, and boarding process.
Southwest
8.0
Very good
4,277 reviews

Crew

8.6

Overall

8.0

Entertainment

7.6

Boarding

8.2

Food

7.1

Comfort

8.0

Reviews

1 / 20
8.0
Excellent

Ila,Mar 2025

HOU - DAL

Our original flight was delayed. We were able to change our flight and got home at close to the same time. Looking forward to when you have assigned seating.
Southwest
8.0
Very good
4,277 reviews
Southwest
8.0
Very good
4,277 reviews

Crew

8.6

Overall

8.0

Entertainment

7.6

Boarding

8.2

Food

7.1

Comfort

8.0

Reviews

1 / 20
8.0
Excellent

Ila,Mar 2025

HOU - DAL

Our original flight was delayed. We were able to change our flight and got home at close to the same time. Looking forward to when you have assigned seating.
Delta
8.0
Very good
7,901 reviews
Southwest
8.0
Very good
4,277 reviews

Crew

8.6

Overall

8.0

Entertainment

7.6

Boarding

8.2

Food

7.1

Comfort

8.0

Reviews

1 / 20
8.0
Excellent

Ila,Mar 2025

HOU - DAL

Our original flight was delayed. We were able to change our flight and got home at close to the same time. Looking forward to when you have assigned seating.
United Airlines
7.4
Good
8,629 reviews
Southwest
8.0
Very good
4,277 reviews

Crew

8.6

Overall

8.0

Entertainment

7.6

Boarding

8.2

Food

7.1

Comfort

8.0

Reviews

1 / 20
8.0
Excellent

Ila,Mar 2025

HOU - DAL

Our original flight was delayed. We were able to change our flight and got home at close to the same time. Looking forward to when you have assigned seating.
American Airlines
7.2
Good
10,000 reviews
Southwest
8.0
Very good
4,277 reviews

Crew

8.6

Overall

8.0

Entertainment

7.6

Boarding

8.2

Food

7.1

Comfort

8.0

Reviews

1 / 20
8.0
Excellent

Ila,Mar 2025

HOU - DAL

Our original flight was delayed. We were able to change our flight and got home at close to the same time. Looking forward to when you have assigned seating.

Related info for your journey

Find useful and relevant information for your journey from Panama City to South Carolina. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly from for flights from Panama City to South Carolina?

    For a flight from Panama City to South Carolina, you will be flying from NW Florida Beaches. Panama City NW Florida Beaches (ECP) is just 16.0 mi from the center of the city.

  • What are the cheapest airlines to fly from Panama City, Florida to South Carolina one-way?

    The cheapest airlines for a one-way flight from Panama City, Florida to South Carolina are Southwest ($219), Delta ($230), and American Airlines ($249).

  • What are the most popular routes from Panama City, Florida to South Carolina?

    Most travelers choose Panama City NW Florida Beaches - Charleston, Panama City NW Florida Beaches - Myrtle Beach Intl or Panama City NW Florida Beaches - Greenville when deciding on the best route from Panama City, Florida to South Carolina.

  • Can I find deals for flights from Panama City to South Carolina that include hotel bookings?

    Yes. In addition to deals on Panama City to South Carolina flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Panama City to South Carolina?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Panama City to South Carolina.

  • Can I find deals for business class flights from Panama City to South Carolina?

    Yes. Cheapflights offers flight deals from Panama City to South Carolina by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Panama City, Florida to South Carolina?

    Currently, August is the cheapest month in which you can book a flight from Panama City, Florida to South Carolina (average of $217). Flying from Panama City, Florida to South Carolina in March is currently the most expensive (average of $335). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

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Alternative routes for Panama City to South Carolina

See prices for flight routes from nearby airports that may be better suited for you.
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Top 2 airlines flying from Panama City to South Carolina

Discover the top 2 airlines that operate flights from Panama City to South Carolina. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated April 8, 2025.
AirlineCheapestAverageFlexibilityOn-time
DeltaCheapest$206Average$466FlexibilityNo cancel feeOn-timeN/A
American AirlinesCheapest$214Average$421FlexibilityNo cancel feeOn-time71%

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