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South Carolina

$126+ Cheap flights from Moline (MLI) to South Carolina

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 10/4. Fares are subject to change and may not be available on all flights or dates of travel.
MLI — CHS
Apr 22 — Apr 291
Tue 4/22
Tue 4/29
1 adult, Economy
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Cheap flight deals from Moline to South Carolina

Keep the following information in mind while searching for Moline to South Carolina flight deals. Data was last updated April 17, 2025.

Most accurate provider

FlightHub
3 stars

Most trusted provider

eDreams
3 stars

Round-trip from

$248
(United Airlines)

One-way from

$126
(American Airlines)

Popular in

June

Cheapest in

February

Average price

$288
Provider with most accurate pricing for Moline Quad-City-Myrtle Beach Intl flight deals.
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Provider most trusted by Cheapflights users for Moline Quad-City-Myrtle Beach Intl flights.
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From Moline Quad-City to South Carolina
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One-way flight from Moline Quad-City to South Carolina
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Highest demand for flights based on searches. 6% potential increase in price ($26 potential increase over avg. RT price).
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Cheapest flight prices on average. 2% potential price decrease ($10 potential savings vs. average RT price).
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Average for round-trip flights in April 2025
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Find flight deals from Moline to South Carolina

Cheapest flights from Moline to South Carolina
Explore the most affordable flight options available from Moline to South Carolina. Find the lowest fares from popular airlines and budget airlines, with prices last updated on April 17, 2025.

This United Airlines deal was found by Cheapflights users on 4/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/236:30 amMLI - MYR
2 stops6h 43mUnited Airlines
Sun 8/314:45 pmMYR - MLI
1 stop5h 22mUnited Airlines
Deal found 4/17$248
This Delta deal was found by Cheapflights users on 4/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/165:15 pmMLI - CHS
1 stop5h 29mDelta
Tue 5/2010:45 amCHS - MLI
1 stop6h 49mDelta
Deal found 4/17$249
This Delta deal was found by Cheapflights users on 4/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 6/205:28 pmMLI - MYR
1 stop5h 39mDelta
Thu 6/261:25 pmMYR - MLI
1 stop4h 23mDelta
Deal found 4/16$249
This Delta deal was found by Cheapflights users on 4/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 6/135:28 pmMLI - SAV
1 stop4h 19mDelta
Wed 6/187:06 pmSAV - MLI
1 stop4h 41mDelta
Deal found 4/16$249
This American Airlines deal was found by Cheapflights users on 4/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/205:00 amMLI - MYR
1 stop6h 16mAmerican Airlines
Sat 5/246:35 pmMYR - MLI
1 stop4h 39mAmerican Airlines
Deal found 4/16$250
This American Airlines deal was found by Cheapflights users on 4/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/163:25 pmMLI - CHS
1 stop6h 25mAmerican Airlines
Tue 5/205:07 amCHS - MLI
2 stops6h 35mAmerican Airlines
Deal found 4/17$254
This American Airlines deal was found by Cheapflights users on 4/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/14:26 pmMLI - GSP
1 stop6h 12mAmerican Airlines
Tue 5/66:36 pmGSP - MLI
1 stop4h 38mAmerican Airlines
Deal found 4/16$259
This American Airlines deal was found by Cheapflights users on 4/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/163:25 pmMLI - CAE
1 stop5h 58mAmerican Airlines
Tue 5/206:02 pmCAE - MLI
1 stop5h 12mAmerican Airlines
Deal found 4/17$299
This American Airlines deal was found by Cheapflights users on 4/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 6/144:20 pmMLI - CLT
Nonstop2h 14mAmerican Airlines
Sat 6/212:38 pmCLT - MLI
Nonstop2h 10mAmerican Airlines
Deal found 4/17$301
This American Airlines deal was found by Cheapflights users on 4/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 6/134:20 pmMLI - SAV
1 stop4h 19mAmerican Airlines
Mon 6/236:14 pmSAV - MLI
1 stop4h 55mAmerican Airlines
Deal found 4/16$319
This Delta deal was found by Cheapflights users on 4/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 6/145:55 amMLI - CLT
1 stop4h 05mDelta
Sat 6/2111:40 amCLT - MLI
1 stop6h 08mDelta
Deal found 4/16$321
This United Airlines deal was found by Cheapflights users on 4/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/278:40 amMLI - CHS
1 stop4h 27mUnited Airlines
Wed 10/111:30 amCHS - MLI
1 stop4h 35mUnited Airlines
Deal found 4/17$359

Cheapflights Fare Finder

Customize your flight search to find flights from Moline to South Carolina that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated April 17, 2025.
Use the filters below to find and compare flights from Moline to South Carolina that are best for you.

Fly from

Moline

Fly to

South Carolina

Route

Depart

Return

Price

MolineMyrtle Beach

MLI - MYR

MLIMYR

Moline Quad-City

Sat 8/23

6:30 am-2:13 pm

2 stops6h 43m

Myrtle Beach Intl

Sun 8/31

4:45 pm-9:07 pm

1 stop5h 22m

$248

MolineCharleston

MLI - CHS

MLICHS

Moline Quad-City

Fri 5/16

5:15 pm-11:44 pm

1 stop5h 29m

Charleston

Tue 5/20

10:45 am-4:34 pm

1 stop6h 49m

$249

MolineMyrtle Beach

MLI - MYR

MLIMYR

Moline Quad-City

Fri 6/20

5:28 pm-12:07 am

1 stop5h 39m

Myrtle Beach Intl

Wed 6/25

1:25 pm-4:48 pm

1 stop4h 23m

$249

MolineSavannah

MLI - SAV

MLISAV

Moline Quad-City

Fri 6/13

5:28 pm-10:47 pm

1 stop4h 19m

Savannah/Hilton Head

Wed 6/18

7:06 pm-10:47 pm

1 stop4h 41m

$249

MolineMyrtle Beach

MLI - MYR

MLIMYR

Moline Quad-City

Tue 5/20

5:00 am-12:16 pm

1 stop6h 16m

Myrtle Beach Intl

Sat 5/24

6:35 pm-10:14 pm

1 stop4h 39m

$250

MolineCharleston

MLI - CHS

MLICHS

Moline Quad-City

Fri 5/16

3:25 pm-10:50 pm

1 stop6h 25m

Charleston

Tue 5/20

5:07 am-10:42 am

2 stops6h 35m

$254

MolineGreenville

MLI - GSP

MLIGSP

Moline Quad-City

Thu 5/1

4:26 pm-11:38 pm

1 stop6h 12m

Greenville

Tue 5/6

6:36 pm-10:14 pm

1 stop4h 38m

$259

MolineColumbia

MLI - CAE

MLICAE

Moline Quad-City

Fri 5/16

3:25 pm-10:23 pm

1 stop5h 58m

Columbia Metropolitan

Tue 5/20

6:02 pm-10:14 pm

1 stop5h 12m

$299

MolineCharlotte

MLI - CLT

MLICLT

Moline Quad-City

Sat 6/14

4:20 pm-7:34 pm

Nonstop2h 14m

Charlotte Douglas

Sat 6/21

2:38 pm-3:48 pm

Nonstop2h 10m

$301

MolineSavannah

MLI - SAV

MLISAV

Moline Quad-City

Fri 6/13

4:20 pm-9:39 pm

1 stop4h 19m

Savannah/Hilton Head

Mon 6/23

6:14 pm-10:09 pm

1 stop4h 55m

$319

Flights are sorted by cheapest round-trip flights first.

Deals found on 4/16

Showing 1-10 of 27 results
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Best time to book a flight from Moline to South Carolina

Have a flexible travel schedule? Discover the best time to fly to South Carolina from Moline with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Moline to South Carolina

What is the cheapest month to book a flight from Moline to South Carolina?

Currently, August is the cheapest month in which you can book a flight from Moline to South Carolina (average of $217). Flying from Moline to South Carolina in March is currently the most expensive (average of $335). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

Rainfall in South Carolina by month

Plan your trip to South Carolina by taking into account the average rainfall totals by month.

In terms of precipitation, rainfall in South Carolina ranges from 3.0 - 6.5 inches per month. July is typically the wettest month, when rainfall can reach 6.5 in. November is typically the driest time to visit South Carolina when rainfall is around 3.0 in.

Temperature in South Carolina by month

Plan your trip to South Carolina by taking into account the average temperature totals by month.

If weather is an important factor for your trip to South Carolina, use this chart to help with planning. For those seeking warmer temperatures, July is the ideal time of year to visit, when temperatures reach an average of 78.8 F. Travelers looking to avoid the cold should look outside of January, when temperatures are typically at their lowest (around 44.6 F).

Reviews of airlines servicing South Carolina

Get insights into the airlines that provide service to South Carolina. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to South Carolina. Reviews last updated April 17, 2025.
Read through reviews of airlines operating flights from Moline to South Carolina, such as Delta, United Airlines and American Airlines. Users have also rated airlines in terms of entertainment options, comfort, food, crew/service, and boarding process.
Delta
8.0
Very good
7,917 reviews

Entertainment

7.9

Boarding

8.2

Comfort

7.9

Food

7.3

Crew

8.5

Overall

8.0

Reviews

1 / 20
10.0
Excellent

Aaron,Oct 2024

TUS - LAX

Delta has consistently been the best U.S. airline for my travels and this flight was no exception
Delta
8.0
Very good
7,917 reviews
Delta
8.0
Very good
7,917 reviews

Entertainment

7.9

Boarding

8.2

Comfort

7.9

Food

7.3

Crew

8.5

Overall

8.0

Reviews

1 / 20
10.0
Excellent

Aaron,Oct 2024

TUS - LAX

Delta has consistently been the best U.S. airline for my travels and this flight was no exception
United Airlines
7.4
Good
8,667 reviews
Delta
8.0
Very good
7,917 reviews

Entertainment

7.9

Boarding

8.2

Comfort

7.9

Food

7.3

Crew

8.5

Overall

8.0

Reviews

1 / 20
10.0
Excellent

Aaron,Oct 2024

TUS - LAX

Delta has consistently been the best U.S. airline for my travels and this flight was no exception
American Airlines
7.2
Good
10,000 reviews
Delta
8.0
Very good
7,917 reviews

Entertainment

7.9

Boarding

8.2

Comfort

7.9

Food

7.3

Crew

8.5

Overall

8.0

Reviews

1 / 20
10.0
Excellent

Aaron,Oct 2024

TUS - LAX

Delta has consistently been the best U.S. airline for my travels and this flight was no exception

Related info for your journey

Find useful and relevant information for your journey from Moline to South Carolina. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly from for flights from Moline to South Carolina?

    Most people fly from Moline Quad-City (MLI) if they book a flight from Moline to South Carolina. Moline Quad-City is conveniently located just 4.0 mi from Moline’s city center.

  • What are the cheapest airlines to fly from Moline to South Carolina one-way?

    One-way options have recently been found by users for as low as $126 on American Airlines. Other airlines that offer cheap prices include Delta from $207 and United Airlines from $215 one-way.

  • What are the most popular routes from Moline to South Carolina?

    Most travelers choose Moline Quad-City - Charlotte Douglas, Moline Quad-City - Myrtle Beach Intl or Moline Quad-City - Savannah/Hilton Head when deciding on the best route from Moline to South Carolina.

  • Can I find deals for flights from Moline to South Carolina that include hotel bookings?

    Yes. In addition to deals on Moline to South Carolina flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Moline to South Carolina?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Moline to South Carolina.

  • Can I find deals for business class flights from Moline to South Carolina?

    Yes. Cheapflights offers flight deals from Moline to South Carolina by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Moline to South Carolina?

    Currently, August is the cheapest month in which you can book a flight from Moline to South Carolina (average of $217). Flying from Moline to South Carolina in March is currently the most expensive (average of $335). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

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Alternative routes for Moline to South Carolina

See prices for flight routes from nearby airports that may be better suited for you.
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Top 3 airlines flying from Moline to South Carolina

Discover the top 3 airlines that operate flights from Moline to South Carolina. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated April 17, 2025.
AirlineCheapestAverageFlexibilityOn-time
United AirlinesCheapest$195Average$393FlexibilityNo cancel feeOn-time69%
American AirlinesCheapest$198Average$410FlexibilityNo cancel feeOn-time71%
DeltaCheapest$208Average$345FlexibilityNo cancel feeOn-timeN/A

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