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$65+ Cheap flights from Missouri to South Carolina

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 12/3. Fares are subject to change and may not be available on all flights or dates of travel.
STL — CHS
nov. 25 — dic. 21
lun. 11/25
lun. 12/2
1 adult, Economy
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Cheap flight deals from Missouri to South Carolina

Discover tips and strategies to find the most affordable flight options for your journey from Missouri (USMO) to South Carolina (USSC). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated noviembre 20, 2024.

Find flight deals from Missouri to South Carolina

Cheapest flights from Missouri to South Carolina
Explore the most affordable flight options available from Missouri to South Carolina. Find the lowest fares from popular airlines and budget airlines, with prices last updated on noviembre 20, 2024.

This American Airlines deal was found by Cheapflights users on 11/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mié. 12/1112:24 pmMCI - CLT
Nonstop2h 18mAmerican Airlines
mié. 12/181:26 pmCLT - MCI
Nonstop2h 27mAmerican Airlines
Deal found 11/20$189
This FlightHub deal was found by Cheapflights users on 11/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure FlightHub is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
lun. 12/166:25 pmMCI - CLT
1 stop17h 54mMultiple Airlines
mié. 12/187:14 pmCLT - MCI
1 stop23h 51mMultiple Airlines
Deal found 11/19$197
This United Airlines deal was found by Cheapflights users on 11/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
jue. 12/192:55 pmMCI - CLT
1 stop6h 19mUnited Airlines
vie. 1/36:28 amCLT - MCI
1 stop5h 18mUnited Airlines
Deal found 11/19$208
This CheapOair deal was found by Cheapflights users on 11/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mié. 12/44:52 pmMCI - CLT
1 stop26h 46mSpirit Airlines
mar. 12/109:33 pmCLT - MCI
1 stop19h 14mSpirit Airlines
Deal found 11/19$213
This CheapOair deal was found by Cheapflights users on 11/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
jue. 12/54:26 pmSTL - MYR
1 stop17h 01mSpirit Airlines
jue. 12/126:00 amMYR - STL
1 stop10h 21mSpirit Airlines
Deal found 11/20$230
This Delta deal was found by Cheapflights users on 11/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mié. 12/2510:23 amMCI - CLT
1 stop6h 40mDelta
lun. 12/306:00 amCLT - MCI
1 stop6h 29mDelta
Deal found 11/20$232
This Mytrip deal was found by Cheapflights users on 11/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
lun. 12/165:00 pmSTL - MYR
3 stops22h 41mMultiple Airlines
jue. 12/196:00 amMYR - STL
1 stop10h 21mMultiple Airlines
Deal found 11/20$249
This Mytrip deal was found by Cheapflights users on 11/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
vie. 12/67:11 pmMCI - CHS
2 stops20h 08mSpirit Airlines
lun. 12/97:45 pmCHS - MCI
2 stops21h 02mSpirit Airlines
Deal found 11/19$249
This CheapOair deal was found by Cheapflights users on 11/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
sáb. 11/237:11 pmMCI - MYR
2 stops14h 21mSpirit Airlines
lun. 12/26:49 pmMYR - MCI
1 stop24h 16mSpirit Airlines
Deal found 11/19$281
This Delta deal was found by Cheapflights users on 11/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
sáb. 12/147:15 amSTL - GSP
1 stop5h 19mDelta
sáb. 1/113:14 pmGSP - STL
1 stop4h 31mDelta
Deal found 11/20$286
This Mytrip deal was found by Cheapflights users on 11/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mié. 12/1112:15 pmSTL - CLT
3 stops22h 47mMultiple Airlines
vie. 12/139:33 pmCLT - STL
2 stops18h 48mMultiple Airlines
Deal found 11/18$287
This American Airlines deal was found by Cheapflights users on 11/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mar. 12/174:52 pmMCI - GSP
1 stop5h 37mAmerican Airlines
mar. 12/315:16 amGSP - MCI
1 stop7h 30mAmerican Airlines
Deal found 11/19$288

Find flights from Missouri to South Carolina within your budget

Customize your flight search to find flights from Missouri to South Carolina that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,629,791 searches. Data last updated noviembre 20, 2024.

Fly from

Any airport

Fly to

Any airport

Route

Depart

Return

Price

Kansas CityCharlotte

MCI - CLT

MCICLT

Kansas City

mié. 12/11

6:30 am-10:01 am

Nonstop2h 31m

Charlotte Douglas

mié. 12/18

9:30 pm-11:03 pm

Nonstop2h 33m

$189

Kansas CityCharlotte

MCI - CLT

MCICLT

Kansas City

lun. 12/16

6:25 pm-1:19 pm

1 stop17h 54m

Charlotte Douglas

mié. 12/18

7:14 pm-6:05 pm

1 stop23h 51m

$197

Kansas CityCharlotte

MCI - CLT

MCICLT

Kansas City

jue. 12/19

2:55 pm-10:14 pm

1 stop6h 19m

Charlotte Douglas

vie. 1/3

6:28 am-10:46 am

1 stop5h 18m

$208

Kansas CityCharlotte

MCI - CLT

MCICLT

Kansas City

mié. 12/4

4:52 pm-8:38 pm

1 stop26h 46m

Charlotte Douglas

mar. 12/10

9:33 pm-3:47 pm

1 stop19h 14m

$213

Kansas CityCharlotte

MCI - CLT

MCICLT

Kansas City

mar. 4/22

4:15 pm-10:14 pm

1 stop4h 59m

Charlotte Douglas

mar. 4/29

10:07 am-1:52 pm

1 stop4h 45m

$216

St. LouisCharleston

STL - CHS

STLCHS

Lambert-St Louis

mar. 1/14

3:48 pm-5:15 pm

1 stop24h 27m

Charleston

mar. 1/21

7:15 am-2:43 pm

1 stop8h 28m

$225

St. LouisMyrtle Beach

STL - MYR

STLMYR

Lambert-St Louis

jue. 12/5

4:26 pm-10:27 am

1 stop17h 01m

Myrtle Beach Intl

jue. 12/12

6:00 am-3:21 pm

1 stop10h 21m

$230

St. LouisMyrtle Beach

STL - MYR

STLMYR

Lambert-St Louis

lun. 12/16

5:00 pm-4:41 pm

3 stops22h 41m

Myrtle Beach Intl

jue. 12/19

6:00 am-3:21 pm

1 stop10h 21m

$249

Kansas CityCharleston

MCI - CHS

MCICHS

Kansas City

vie. 12/6

7:11 pm-4:19 pm

2 stops20h 08m

Charleston

lun. 12/9

7:45 pm-3:47 pm

2 stops21h 02m

$249

St. LouisGreenville

STL - GSP

STLGSP

Lambert-St Louis

sáb. 12/14

7:15 am-1:34 pm

1 stop5h 19m

Greenville

sáb. 1/11

3:14 pm-6:45 pm

1 stop4h 31m

$286

Flights are sorted by cheapest round-trip flights first.

Deals found on 11/19

Showing 1-10 of 60 results
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Best time to book a flight from Missouri to South Carolina

Have a flexible travel schedule? Discover the best time to fly to South Carolina from Missouri with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Travel insights for flights from Missouri to South Carolina

Get recent, data-driven insights about flights from Missouri to South Carolina including ideal travel times, pricing trends, and more.

What is the cheapest month to book a flight from Missouri to South Carolina?

Currently, August is the cheapest month in which you can book a flight from Missouri to South Carolina (average of $217). Flying from Missouri to South Carolina in April is currently the most expensive (average of $314). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from MO to SC?

Find hourly flight availability from Missouri to South Carolina. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated noviembre 20, 2024.

When flying from Missouri to South Carolina, the time of day you decide to fly out makes little to no difference towards the overall price you’ll pay on tickets.

Rainfall in South Carolina by month

Plan your trip to South Carolina by taking into account the average rainfall totals by month.

In terms of precipitation, rainfall in South Carolina ranges from 3.0 - 6.5 inches per month. July is typically the wettest month, when rainfall can reach 6.5 in. November is typically the driest time to visit South Carolina when rainfall is around 3.0 in.

Temperature in South Carolina by month

Plan your trip to South Carolina by taking into account the average temperature totals by month.

If weather is an important factor for your trip to South Carolina, use this chart to help with planning. For those seeking warmer temperatures, July is the ideal time of year to visit, when temperatures reach an average of 78.8 F. Travelers looking to avoid the cold should look outside of January, when temperatures are typically at their lowest (around 44.6 F).

Reviews of airlines servicing South Carolina

Get insights into the airlines that provide service to South Carolina. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to South Carolina. Reviews last updated noviembre 20, 2024.
Read reviews from past customers who have flown United Airlines, Delta and Southwest from Missouri to South Carolina. You can also see how each airline stacks up in terms of entertainment options, comfort, food, crew/service, and boarding process.
Southwest
8.1
Very good
5,014 reviews

Boarding

8.2

Overall

8.1

Crew

8.7

Entertainment

7.7

Comfort

8.1

Food

7.2

Reviews

1 / 10

Great service throughout our flight. Easy boarding with early bird check in

Southwest
8.1
Very good
5,014 reviews
Southwest
8.1
Very good
5,014 reviews

Boarding

8.2

Overall

8.1

Crew

8.7

Entertainment

7.7

Comfort

8.1

Food

7.2

Reviews

1 / 10

Great service throughout our flight. Easy boarding with early bird check in

Alaska Airlines
8.0
Very good
9,461 reviews
Southwest
8.1
Very good
5,014 reviews

Boarding

8.2

Overall

8.1

Crew

8.7

Entertainment

7.7

Comfort

8.1

Food

7.2

Reviews

1 / 10

Great service throughout our flight. Easy boarding with early bird check in

Delta
8.0
Very good
8,756 reviews
Southwest
8.1
Very good
5,014 reviews

Boarding

8.2

Overall

8.1

Crew

8.7

Entertainment

7.7

Comfort

8.1

Food

7.2

Reviews

1 / 10

Great service throughout our flight. Easy boarding with early bird check in

United Airlines
7.4
Good
9,171 reviews
Southwest
8.1
Very good
5,014 reviews

Boarding

8.2

Overall

8.1

Crew

8.7

Entertainment

7.7

Comfort

8.1

Food

7.2

Reviews

1 / 10

Great service throughout our flight. Easy boarding with early bird check in

American Airlines
7.2
Good
10,000 reviews
Southwest
8.1
Very good
5,014 reviews

Boarding

8.2

Overall

8.1

Crew

8.7

Entertainment

7.7

Comfort

8.1

Food

7.2

Reviews

1 / 10

Great service throughout our flight. Easy boarding with early bird check in

Related info for your journey

Find useful and relevant information for your journey from Missouri to South Carolina. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What are the cheapest airlines to fly from Missouri to South Carolina one-way?

    For one-way options, check prices for Frontier. According to our data, you can fly for as low as $65. Users have also found prices from $95 and $101 on American Airlines and Spirit Airlines, respectively.

  • Can I find deals for flights from Missouri to South Carolina that include hotel bookings?

    Yes. In addition to deals on Missouri to South Carolina flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Missouri to South Carolina?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Missouri to South Carolina.

  • Can I find deals for business class flights from Missouri to South Carolina?

    Yes. Cheapflights offers flight deals from Missouri to South Carolina by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Missouri to South Carolina?

    Currently, August is the cheapest month in which you can book a flight from Missouri to South Carolina (average of $217). Flying from Missouri to South Carolina in April is currently the most expensive (average of $314). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

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Alternative routes for Missouri to South Carolina

See prices for flight routes from nearby airports that may be better suited for you.
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Top 5 airlines flying from Missouri to South Carolina

Discover the top 5 airlines that operate flights from Missouri to South Carolina. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,629,791 searches. Data last updated noviembre 20, 2024.
AirlineCheapestAverageFlexibilityOn-time
Spirit AirlinesCheapest$119Average$236FlexibilityNo cancel feeOn-time65%
American AirlinesCheapest$174Average$402FlexibilityNo cancel feeOn-time71%
DeltaCheapest$218Average$376FlexibilityNo cancel feeOn-timeN/A
United AirlinesCheapest$303Average$469FlexibilityNo cancel feeOn-time69%
SouthwestCheapest$306Average$412FlexibilityNo cancel feeOn-time63%
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