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South Carolina

$56+ Cheap flights from Mississippi to South Carolina

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 3/19. Fares are subject to change and may not be available on all flights or dates of travel.
JAN — CHS
Feb 25 — Mar 41
Tue 2/25
Tue 3/4
1 adult, Economy
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Cheap flight deals from Mississippi to South Carolina

Keep the following information in mind while searching for Mississippi to South Carolina flight deals. Data was last updated February 20, 2025.

Most accurate provider

FlightHub
3 stars

Most trusted provider

FlightHub
3 stars

Round-trip from

$125
(FlightHub)

One-way from

$56
(Cheapflightsfares)
Provider with most accurate pricing for Jackson-Evers Intl-Myrtle Beach Intl flight deals.
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Provider most trusted by Cheapflights users for Jackson-Evers Intl-Myrtle Beach Intl flights.
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From Mississippi to South Carolina
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One-way flight from Mississippi to South Carolina
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Find flight deals from Mississippi to South Carolina

Cheapest flights from Mississippi to South Carolina
Explore the most affordable flight options available from Mississippi to South Carolina. Find the lowest fares from popular airlines and budget airlines, with prices last updated on February 20, 2025.

This CheapOair deal was found by Cheapflights users on 2/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/107:44 pmMEM - CLT
1 stop22h 04mMultiple Airlines
Mon 4/145:21 pmCLT - MEM
1 stop25h 35mMultiple Airlines
Deal found 2/20$154
This FlightHub deal was found by Cheapflights users on 2/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure FlightHub is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/176:51 pmMEM - CLT
1 stop13h 44mSpirit Airlines
Tue 4/227:00 amCLT - MEM
1 stop11h 56mSpirit Airlines
Deal found 2/20$160
This FlightHub deal was found by Cheapflights users on 2/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure FlightHub is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 3/228:56 amMEM - CHS
1 stop6h 38mSpirit Airlines
Thu 3/2711:40 amCHS - MEM
1 stop13h 19mSpirit Airlines
Deal found 2/20$163
This Booking.com deal was found by Cheapflights users on 2/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Booking.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 3/97:53 pmMEM - CLT
1 stop22h 11mFrontier
Sun 3/1610:03 pmCLT - MEM
1 stop22h 20mFrontier
Deal found 2/20$180
This Mytrip deal was found by Cheapflights users on 2/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 3/72:35 pmMEM - CHS
1 stop19h 45mMultiple Airlines
Sun 3/165:48 pmCHS - MEM
1 stop20h 32mMultiple Airlines
Deal found 2/20$203
This Delta deal was found by Cheapflights users on 2/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 4/124:55 pmGPT - SAV
1 stop3h 23mDelta
Thu 4/175:30 amSAV - GPT
1 stop4h 29mDelta
Deal found 2/20$229
This Delta deal was found by Cheapflights users on 2/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/168:05 amMEM - CAE
1 stop5h 16mDelta
Sat 4/197:00 amCAE - MEM
1 stop4h 55mDelta
Deal found 2/19$249
This American Airlines deal was found by Cheapflights users on 2/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 4/126:42 pmGPT - SAV
1 stop4h 07mAmerican Airlines
Fri 4/186:14 pmSAV - GPT
1 stop4h 28mAmerican Airlines
Deal found 2/19$254
This American Airlines deal was found by Cheapflights users on 2/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 4/87:15 amMEM - CHS
1 stop5h 51mAmerican Airlines
Thu 4/106:08 pmCHS - MEM
1 stop6h 37mAmerican Airlines
Deal found 2/20$257
This American Airlines deal was found by Cheapflights users on 2/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/212:29 pmMOB - CLT
1 stop18h 56mAmerican Airlines
Sat 5/311:10 amCLT - MOB
Nonstop2h 08mAmerican Airlines
Deal found 2/19$274
This Delta deal was found by Cheapflights users on 2/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 3/112:06 pmMEM - CHS
1 stop6h 04mDelta
Thu 3/135:35 amCHS - MEM
1 stop3h 32mDelta
Deal found 2/20$277
This Mytrip deal was found by Cheapflights users on 2/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/176:51 pmMEM - SAV
1 stop27h 22mMultiple Airlines
Mon 4/2112:34 pmSAV - MEM
2 stops32h 54mMultiple Airlines
Deal found 2/20$282

Find flights from Mississippi to South Carolina within your budget

Customize your flight search to find flights from Mississippi to South Carolina that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated February 20, 2025.

Fly from

Mississippi

Fly to

South Carolina

Route

Depart

Return

Price

MemphisCharlotte

MEM - CLT

MEMCLT

Memphis

Thu 4/10

7:44 pm-6:48 pm

1 stop22h 04m

Charlotte Douglas

Mon 4/14

5:21 pm-5:56 pm

1 stop25h 35m

$154

MemphisCharlotte

MEM - CLT

MEMCLT

Memphis

Thu 4/17

6:51 pm-9:35 am

1 stop13h 44m

Charlotte Douglas

Tue 4/22

7:00 am-5:56 pm

1 stop11h 56m

$160

MemphisCharleston

MEM - CHS

MEMCHS

Memphis

Sat 3/22

8:56 am-4:34 pm

1 stop6h 38m

Charleston

Thu 3/27

11:40 am-11:59 pm

1 stop13h 19m

$163

MemphisCharlotte

MEM - CLT

MEMCLT

Memphis

Sun 3/9

7:53 pm-7:04 pm

1 stop22h 11m

Charlotte Douglas

Sun 3/16

10:03 pm-7:23 pm

1 stop22h 20m

$180

MemphisCharleston

MEM - CHS

MEMCHS

Memphis

Fri 3/7

2:35 pm-11:20 am

1 stop19h 45m

Charleston

Sun 3/16

5:48 pm-1:20 pm

1 stop20h 32m

$203

GulfportSavannah

GPT - SAV

GPTSAV

Gulfport Biloxi Regional

Sat 4/12

4:55 pm-9:18 pm

1 stop3h 23m

Savannah/Hilton Head

Thu 4/17

5:30 am-8:59 am

1 stop4h 29m

$229

MemphisColumbia

MEM - CAE

MEMCAE

Memphis

Wed 4/16

8:05 am-2:21 pm

1 stop5h 16m

Columbia Metropolitan

Sat 4/19

7:00 am-10:55 am

1 stop4h 55m

$249

GulfportSavannah

GPT - SAV

GPTSAV

Gulfport Biloxi Regional

Sat 4/12

6:42 pm-11:49 pm

1 stop4h 07m

Savannah/Hilton Head

Fri 4/18

6:14 pm-9:42 pm

1 stop4h 28m

$254

MemphisCharleston

MEM - CHS

MEMCHS

Memphis

Tue 4/8

7:15 am-2:06 pm

1 stop5h 51m

Charleston

Thu 4/10

6:08 pm-11:45 pm

1 stop6h 37m

$257

JacksonCharleston

JAN - CHS

JANCHS

Jackson-Evers Intl

Tue 5/6

2:48 pm-9:31 pm

1 stop5h 43m

Charleston

Thu 5/8

5:30 am-8:32 am

1 stop4h 02m

$257

Flights are sorted by cheapest round-trip flights first.

Deals found on 2/20

Showing 1-10 of 55 results
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Best time to book a flight from Mississippi to South Carolina

Have a flexible travel schedule? Discover the best time to fly to South Carolina from Mississippi with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Travel insights for flights from Mississippi to South Carolina

Get recent, data-driven insights about flights from Mississippi to South Carolina including ideal travel times, pricing trends, and more.

What is the cheapest month to book a flight from Mississippi to South Carolina?

Currently, August is the cheapest month in which you can book a flight from Mississippi to South Carolina (average of $217). Flying from Mississippi to South Carolina in March is currently the most expensive (average of $335). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from MS to SC?

Find hourly flight availability from Mississippi to South Carolina. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated February 20, 2025.

Regardless of the time of day you decide to fly, the ticket price will remain around the same. Book flights from Mississippi to South Carolina as you normally would.

Rainfall in South Carolina by month

Plan your trip to South Carolina by taking into account the average rainfall totals by month.

In terms of precipitation, rainfall in South Carolina ranges from 3.0 - 6.5 inches per month. July is typically the wettest month, when rainfall can reach 6.5 in. November is typically the driest time to visit South Carolina when rainfall is around 3.0 in.

Temperature in South Carolina by month

Plan your trip to South Carolina by taking into account the average temperature totals by month.

If weather is an important factor for your trip to South Carolina, use this chart to help with planning. For those seeking warmer temperatures, July is the ideal time of year to visit, when temperatures reach an average of 78.8 F. Travelers looking to avoid the cold should look outside of January, when temperatures are typically at their lowest (around 44.6 F).

Reviews of airlines servicing South Carolina

Get insights into the airlines that provide service to South Carolina. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to South Carolina. Reviews last updated February 20, 2025.
Read through reviews of airlines operating flights from Mississippi to South Carolina, such as Southwest, Delta and United Airlines. You can also see how each airline compares in terms of entertainment options, comfort, food, crew/service, and boarding process.
Southwest
8.1
Very good
4,411 reviews

Entertainment

7.6

Boarding

8.2

Overall

8.1

Comfort

8.1

Food

7.1

Crew

8.7

Reviews

1 / 20

2.0
Mediocre

Anonymous,Feb 2025

MCO - STL

Cancelled at last minute, SWA unable to assist in formulating alternate plans. Wound up renting a car and driving 13 hours to beat bad weather forecast at home. Not SWA’s fault that there was significant bad weather across the country.

Southwest
8.1
Very good
4,411 reviews
Southwest
8.1
Very good
4,411 reviews

Entertainment

7.6

Boarding

8.2

Overall

8.1

Comfort

8.1

Food

7.1

Crew

8.7

Reviews

1 / 20

2.0
Mediocre

Anonymous,Feb 2025

MCO - STL

Cancelled at last minute, SWA unable to assist in formulating alternate plans. Wound up renting a car and driving 13 hours to beat bad weather forecast at home. Not SWA’s fault that there was significant bad weather across the country.

Delta
8.0
Very good
8,219 reviews
Southwest
8.1
Very good
4,411 reviews

Entertainment

7.6

Boarding

8.2

Overall

8.1

Comfort

8.1

Food

7.1

Crew

8.7

Reviews

1 / 20

2.0
Mediocre

Anonymous,Feb 2025

MCO - STL

Cancelled at last minute, SWA unable to assist in formulating alternate plans. Wound up renting a car and driving 13 hours to beat bad weather forecast at home. Not SWA’s fault that there was significant bad weather across the country.

United Airlines
7.4
Good
8,765 reviews
Southwest
8.1
Very good
4,411 reviews

Entertainment

7.6

Boarding

8.2

Overall

8.1

Comfort

8.1

Food

7.1

Crew

8.7

Reviews

1 / 20

2.0
Mediocre

Anonymous,Feb 2025

MCO - STL

Cancelled at last minute, SWA unable to assist in formulating alternate plans. Wound up renting a car and driving 13 hours to beat bad weather forecast at home. Not SWA’s fault that there was significant bad weather across the country.

Allegiant Air
7.3
Good
765 reviews
Southwest
8.1
Very good
4,411 reviews

Entertainment

7.6

Boarding

8.2

Overall

8.1

Comfort

8.1

Food

7.1

Crew

8.7

Reviews

1 / 20

2.0
Mediocre

Anonymous,Feb 2025

MCO - STL

Cancelled at last minute, SWA unable to assist in formulating alternate plans. Wound up renting a car and driving 13 hours to beat bad weather forecast at home. Not SWA’s fault that there was significant bad weather across the country.

American Airlines
7.2
Good
10,000 reviews
Southwest
8.1
Very good
4,411 reviews

Entertainment

7.6

Boarding

8.2

Overall

8.1

Comfort

8.1

Food

7.1

Crew

8.7

Reviews

1 / 20

2.0
Mediocre

Anonymous,Feb 2025

MCO - STL

Cancelled at last minute, SWA unable to assist in formulating alternate plans. Wound up renting a car and driving 13 hours to beat bad weather forecast at home. Not SWA’s fault that there was significant bad weather across the country.

Related info for your journey

Find useful and relevant information for your journey from Mississippi to South Carolina. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What are the cheapest airlines to fly from Mississippi to South Carolina one-way?

    For one-way options, check prices for Spirit Airlines. According to our data, you can fly for as low as $56. Users have also found prices from $164 and $169 on Delta and Southwest, respectively.

  • Can I find deals for flights from Mississippi to South Carolina that include hotel bookings?

    Yes. In addition to deals on Mississippi to South Carolina flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Mississippi to South Carolina?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Mississippi to South Carolina.

  • Can I find deals for business class flights from Mississippi to South Carolina?

    Yes. Cheapflights offers flight deals from Mississippi to South Carolina by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Mississippi to South Carolina?

    Currently, August is the cheapest month in which you can book a flight from Mississippi to South Carolina (average of $217). Flying from Mississippi to South Carolina in March is currently the most expensive (average of $335). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Browse thousands of different options on Cheapflights for your next trip

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Alternative routes for Mississippi to South Carolina

See prices for flight routes from nearby airports that may be better suited for you.
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Top 2 airlines flying from Mississippi to South Carolina

Discover the top 2 airlines that operate flights from Mississippi to South Carolina. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated February 20, 2025.
AirlineCheapestAverageFlexibilityOn-time
DeltaCheapest$206Average$424FlexibilityNo cancel feeOn-timeN/A
American AirlinesCheapest$208Average$460FlexibilityNo cancel feeOn-time71%
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