South Carolina

$99+ Cheap flights from Mississippi to South Carolina

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 2/21. Fares are subject to change and may not be available on all flights or dates of travel.
JAN — CHS
Jan 26 — Feb 21
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Cheap flight deals from Mississippi to South Carolina

Discover tips and strategies to find the most affordable flight options for your journey from Mississippi (USMS) to South Carolina (USSC). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated January 21, 2025.

Round-trip from

$198
(CheapOair)

One-way from

$99
(Cheapflightsfares)
From Mississippi to South Carolina
One-way flight from Mississippi to South Carolina

Find flight deals from Mississippi to South Carolina

Cheapest flights from Mississippi to South Carolina
Explore the most affordable flight options available from Mississippi to South Carolina. Find the lowest fares from popular airlines and budget airlines, with prices last updated on January 21, 2025.

This CheapOair deal was found by Cheapflights users on 1/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 2/216:18 amMEM - CLT
1 stop12h 07mSpirit Airlines
Mon 3/39:40 pmCLT - MEM
1 stop22h 32mSpirit Airlines
Deal found 1/20$198
This American Airlines deal was found by Cheapflights users on 1/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 2/195:10 amMEM - CAE
1 stop4h 26mAmerican Airlines
Sat 2/226:01 pmCAE - MEM
1 stop6h 43mAmerican Airlines
Deal found 1/21$199
This CheapOair deal was found by Cheapflights users on 1/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 2/65:34 pmMEM - CLT
1 stop19h 53mMultiple Airlines
Sun 2/97:15 pmCLT - MEM
1 stop22h 11mMultiple Airlines
Deal found 1/21$216
This CheapOair deal was found by Cheapflights users on 1/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 3/94:19 pmMEM - MYR
1 stop14h 35mSpirit Airlines
Wed 3/126:30 amMYR - MEM
1 stop9h 54mSpirit Airlines
Deal found 1/20$237
This Delta deal was found by Cheapflights users on 1/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 2/185:57 pmMEM - GSP
1 stop4h 52mDelta
Tue 2/2511:54 amGSP - MEM
1 stop5h 58mDelta
Deal found 1/19$247
This Delta deal was found by Cheapflights users on 1/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 5/267:00 amMEM - CAE
1 stop6h 11mDelta
Wed 7/96:50 pmCAE - MEM
1 stop4h 58mDelta
Deal found 1/21$249
This American Airlines deal was found by Cheapflights users on 1/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 2/195:10 amMEM - SAV
1 stop4h 12mAmerican Airlines
Mon 2/248:24 pmSAV - MEM
1 stop4h 20mAmerican Airlines
Deal found 1/21$257
This American Airlines deal was found by Cheapflights users on 1/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 2/185:10 amMEM - MYR
1 stop6h 07mAmerican Airlines
Tue 2/255:10 amMYR - MEM
1 stop6h 09mAmerican Airlines
Deal found 1/20$257
This American Airlines deal was found by Cheapflights users on 1/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 2/186:56 pmMEM - CHS
1 stop4h 01mAmerican Airlines
Tue 2/256:16 pmCHS - MEM
1 stop6h 28mAmerican Airlines
Deal found 1/21$257
This Delta deal was found by Cheapflights users on 1/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 2/46:05 amBTR - SAV
1 stop4h 02mDelta
Sat 2/82:35 pmSAV - BTR
1 stop3h 25mDelta
Deal found 1/20$259
This American Airlines deal was found by Cheapflights users on 1/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 2/410:34 amBTR - SAV
2 stops10h 19mAmerican Airlines
Sat 2/84:18 pmSAV - BTR
1 stop6h 37mAmerican Airlines
Deal found 1/20$264
This Mytrip deal was found by Cheapflights users on 1/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 3/210:20 amMEM - CHS
1 stop9h 59mMultiple Airlines
Wed 3/510:48 amCHS - MEM
2 stops21h 59mMultiple Airlines
Deal found 1/21$276

Find flights from Mississippi to South Carolina within your budget

Customize your flight search to find flights from Mississippi to South Carolina that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated January 21, 2025.

Fly from

Any airport

Fly to

Any airport

Route

Depart

Return

Price

MemphisCharlotte

MEM - CLT

MEMCLT

Memphis

Fri 2/21

6:18 am-7:25 pm

1 stop12h 07m

Charlotte Douglas

Mon 3/3

9:40 pm-7:12 pm

1 stop22h 32m

$198

MemphisColumbia

MEM - CAE

MEMCAE

Memphis

Wed 2/19

5:10 am-10:36 am

1 stop4h 26m

Columbia Metropolitan

Sat 2/22

6:01 pm-11:44 pm

1 stop6h 43m

$199

MemphisCharlotte

MEM - CLT

MEMCLT

Memphis

Thu 2/6

5:34 pm-2:27 pm

1 stop19h 53m

Charlotte Douglas

Sun 2/9

7:15 pm-4:26 pm

1 stop22h 11m

$216

MemphisMyrtle Beach

MEM - MYR

MEMMYR

Memphis

Sun 3/9

4:19 pm-7:54 am

1 stop14h 35m

Myrtle Beach Intl

Wed 3/12

6:30 am-3:24 pm

1 stop9h 54m

$237

MemphisGreenville

MEM - GSP

MEMGSP

Memphis

Tue 2/18

5:57 pm-11:49 pm

1 stop4h 52m

Greenville

Tue 2/25

11:54 am-4:52 pm

1 stop5h 58m

$247

MemphisColumbia

MEM - CAE

MEMCAE

Memphis

Mon 5/26

7:00 am-2:11 pm

1 stop6h 11m

Columbia Metropolitan

Wed 7/9

6:50 pm-10:48 pm

1 stop4h 58m

$249

MemphisSavannah

MEM - SAV

MEMSAV

Memphis

Wed 2/19

5:10 am-10:22 am

1 stop4h 12m

Savannah/Hilton Head

Mon 2/24

8:24 pm-11:44 pm

1 stop4h 20m

$257

MemphisMyrtle Beach

MEM - MYR

MEMMYR

Memphis

Tue 2/18

5:10 am-12:17 pm

1 stop6h 07m

Myrtle Beach Intl

Tue 2/25

5:10 am-10:19 am

1 stop6h 09m

$257

MemphisCharleston

MEM - CHS

MEMCHS

Memphis

Tue 2/18

6:56 pm-11:57 pm

1 stop4h 01m

Charleston

Tue 2/25

6:16 pm-11:44 pm

1 stop6h 28m

$257

Baton RougeSavannah

BTR - SAV

BTRSAV

Baton Rouge Ryan

Tue 2/4

6:05 am-11:07 am

1 stop4h 02m

Savannah/Hilton Head

Sat 2/8

2:35 pm-5:00 pm

1 stop3h 25m

$259

Flights are sorted by cheapest round-trip flights first.

Deals found on 1/20

Showing 1-10 of 55 results
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Best time to book a flight from Mississippi to South Carolina

Have a flexible travel schedule? Discover the best time to fly to South Carolina from Mississippi with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Travel insights for flights from Mississippi to South Carolina

Get recent, data-driven insights about flights from Mississippi to South Carolina including ideal travel times, pricing trends, and more.

What is the cheapest month to book a flight from Mississippi to South Carolina?

Currently, August is the cheapest month in which you can book a flight from Mississippi to South Carolina (average of $217). Flying from Mississippi to South Carolina in March is currently the most expensive (average of $335). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from MS to SC?

Find hourly flight availability from Mississippi to South Carolina. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated January 21, 2025.

Regardless of the time of day you decide to fly, the ticket price will remain around the same. Book flights from Mississippi to South Carolina as you normally would.

Rainfall in South Carolina by month

Plan your trip to South Carolina by taking into account the average rainfall totals by month.

In terms of precipitation, rainfall in South Carolina ranges from 3.0 - 6.5 inches per month. July is typically the wettest month, when rainfall can reach 6.5 in. November is typically the driest time to visit South Carolina when rainfall is around 3.0 in.

Temperature in South Carolina by month

Plan your trip to South Carolina by taking into account the average temperature totals by month.

If weather is an important factor for your trip to South Carolina, use this chart to help with planning. For those seeking warmer temperatures, July is the ideal time of year to visit, when temperatures reach an average of 78.8 F. Travelers looking to avoid the cold should look outside of January, when temperatures are typically at their lowest (around 44.6 F).

Reviews of airlines servicing South Carolina

Get insights into the airlines that provide service to South Carolina. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to South Carolina. Reviews last updated January 21, 2025.
Read through reviews of airlines operating flights from Mississippi to South Carolina, such as Southwest, Delta and Spirit Airlines. You can also see how each airline compares in terms of entertainment options, comfort, food, crew/service, and boarding process.
8.1
Very good
4,662 reviews

Food

7.2

Entertainment

7.7

Boarding

8.2

Comfort

8.1

Crew

8.7

Overall

8.1

Reviews

1 / 10

We BARELY made the connection and when we got onboard we were treated like disobedient children who should have arrived earlier because we had to ask other passengers to move so we could sit with our kids. The flight attendants on the first flight were nice but the second one, they were snippy and fairly rude.

8.1
Very good
4,662 reviews
8.1
Very good
4,662 reviews

Food

7.2

Entertainment

7.7

Boarding

8.2

Comfort

8.1

Crew

8.7

Overall

8.1

Reviews

1 / 10

We BARELY made the connection and when we got onboard we were treated like disobedient children who should have arrived earlier because we had to ask other passengers to move so we could sit with our kids. The flight attendants on the first flight were nice but the second one, they were snippy and fairly rude.

8.0
Very good
8,521 reviews
8.1
Very good
4,662 reviews

Food

7.2

Entertainment

7.7

Boarding

8.2

Comfort

8.1

Crew

8.7

Overall

8.1

Reviews

1 / 10

We BARELY made the connection and when we got onboard we were treated like disobedient children who should have arrived earlier because we had to ask other passengers to move so we could sit with our kids. The flight attendants on the first flight were nice but the second one, they were snippy and fairly rude.

7.4
Good
8,985 reviews
8.1
Very good
4,662 reviews

Food

7.2

Entertainment

7.7

Boarding

8.2

Comfort

8.1

Crew

8.7

Overall

8.1

Reviews

1 / 10

We BARELY made the connection and when we got onboard we were treated like disobedient children who should have arrived earlier because we had to ask other passengers to move so we could sit with our kids. The flight attendants on the first flight were nice but the second one, they were snippy and fairly rude.

7.4
Good
801 reviews
8.1
Very good
4,662 reviews

Food

7.2

Entertainment

7.7

Boarding

8.2

Comfort

8.1

Crew

8.7

Overall

8.1

Reviews

1 / 10

We BARELY made the connection and when we got onboard we were treated like disobedient children who should have arrived earlier because we had to ask other passengers to move so we could sit with our kids. The flight attendants on the first flight were nice but the second one, they were snippy and fairly rude.

7.2
Good
10,000 reviews
8.1
Very good
4,662 reviews

Food

7.2

Entertainment

7.7

Boarding

8.2

Comfort

8.1

Crew

8.7

Overall

8.1

Reviews

1 / 10

We BARELY made the connection and when we got onboard we were treated like disobedient children who should have arrived earlier because we had to ask other passengers to move so we could sit with our kids. The flight attendants on the first flight were nice but the second one, they were snippy and fairly rude.

Related info for your journey

Find useful and relevant information for your journey from Mississippi to South Carolina. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
  • What are the cheapest airlines to fly from Mississippi to South Carolina one-way?

    For one-way options, check prices for Spirit Airlines. According to our data, you can fly for as low as $99. Users have also found prices from $124 and $164 on United Airlines and Delta, respectively.

  • Can I find deals for flights from Mississippi to South Carolina that include hotel bookings?

    Yes. In addition to deals on Mississippi to South Carolina flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Mississippi to South Carolina?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Mississippi to South Carolina.

  • Can I find deals for business class flights from Mississippi to South Carolina?

    Yes. Cheapflights offers flight deals from Mississippi to South Carolina by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Mississippi to South Carolina?

    Currently, August is the cheapest month in which you can book a flight from Mississippi to South Carolina (average of $217). Flying from Mississippi to South Carolina in March is currently the most expensive (average of $335). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Browse thousands of different options on Cheapflights for your next trip

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Alternative routes for Mississippi to South Carolina

See prices for flight routes from nearby airports that may be better suited for you.

Top 2 airlines flying from Mississippi to South Carolina

Discover the top 2 airlines that operate flights from Mississippi to South Carolina. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated January 21, 2025.
AirlineCheapestAverageFlexibilityOn-time
DeltaCheapest$206Average$415FlexibilityNo cancel feeOn-timeN/A
American AirlinesCheapest$208Average$421FlexibilityNo cancel feeOn-time71%
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