South Carolina

$73+ Cheap flights from Mississippi to South Carolina

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 4/29. Fares are subject to change and may not be available on all flights or dates of travel.
JAN — CHS
Apr 6 — Apr 131
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Cheap flight deals from Mississippi to South Carolina

Keep the following information in mind while searching for Mississippi to South Carolina flight deals. Data was last updated April 1, 2025.

Most accurate provider

FlightHub
3 stars

Most trusted provider

FlightHub
3 stars

Round-trip from

$173
(Mytrip)

One-way from

$73
(Mytrip)
Provider with most accurate pricing for Jackson-Evers Intl-Myrtle Beach Intl flight deals.
Provider most trusted by Cheapflights users for Jackson-Evers Intl-Myrtle Beach Intl flights.
From Mississippi to South Carolina
One-way flight from Mississippi to South Carolina

Find flight deals from Mississippi to South Carolina

Cheapest flights from Mississippi to South Carolina
Explore the most affordable flight options available from Mississippi to South Carolina. Find the lowest fares from popular airlines and budget airlines, with prices last updated on April 1, 2025.

This Mytrip deal was found by Cheapflights users on 4/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 5/57:39 pmMEM - CLT
1 stop13h 33mSpirit Airlines
Fri 5/96:34 pmCLT - MEM
1 stop22h 45mSpirit Airlines
Deal found 4/1$173
This Mytrip deal was found by Cheapflights users on 3/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/105:14 pmMEM - MYR
1 stop16h 45mSpirit Airlines
Mon 5/127:25 pmMYR - MEM
1 stop21h 54mSpirit Airlines
Deal found 3/31$182
This Mytrip deal was found by Cheapflights users on 4/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/16:51 pmMEM - CHS
1 stop13h 45mMultiple Airlines
Sat 5/37:15 pmCHS - MEM
1 stop13h 42mMultiple Airlines
Deal found 4/1$211
This Mytrip deal was found by Cheapflights users on 4/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/95:14 pmMEM - CHS
2 stops14h 24mSpirit Airlines
Sun 5/119:43 amCHS - MEM
1 stop8h 46mSpirit Airlines
Deal found 4/1$230
This Delta deal was found by Cheapflights users on 4/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 4/206:00 amBTR - CHS
1 stop6h 41mDelta
Tue 4/298:05 amCHS - BTR
1 stop6h 18mDelta
Deal found 4/1$243
This Delta deal was found by Cheapflights users on 3/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/167:05 amMEM - CAE
1 stop6h 14mDelta
Sat 4/191:48 pmCAE - MEM
1 stop5h 22mDelta
Deal found 3/31$248
This Delta deal was found by Cheapflights users on 4/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 4/267:05 amMEM - MYR
1 stop5h 38mDelta
Tue 4/297:02 pmMYR - MEM
1 stop5h 15mDelta
Deal found 4/1$249
This American Airlines deal was found by Cheapflights users on 4/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/274:32 pmBTR - CHS
1 stop4h 32mAmerican Airlines
Tue 6/35:15 pmCHS - BTR
1 stop5h 53mAmerican Airlines
Deal found 4/1$249
This Mytrip deal was found by Cheapflights users on 3/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/237:39 pmMEM - CLT
1 stop12h 57mMultiple Airlines
Sat 7/2611:52 amCLT - MEM
1 stop24h 30mMultiple Airlines
Deal found 3/31$253
This CheapOair deal was found by Cheapflights users on 3/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/37:44 pmMEM - CLT
1 stop22h 04mFrontier
Sat 4/57:47 pmCLT - MEM
1 stop23h 52mFrontier
Deal found 3/31$260
This American Airlines deal was found by Cheapflights users on 3/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 5/259:20 amMEM - MYR
1 stop5h 08mAmerican Airlines
Thu 5/297:54 pmMYR - MEM
1 stop4h 50mAmerican Airlines
Deal found 3/30$268
This Delta deal was found by Cheapflights users on 3/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/177:05 amMEM - SAV
1 stop5h 54mDelta
Tue 5/205:30 amSAV - MEM
1 stop4h 51mDelta
Deal found 3/31$272

Cheapflights Fare Finder

Customize your flight search to find flights from Mississippi to South Carolina that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated April 1, 2025.
Use the filters below to find and compare flights from Mississippi to South Carolina that are best for you.

Fly from

Mississippi

Fly to

South Carolina

Route

Depart

Return

Price

MemphisCharlotte

MEM - CLT

MEMCLT

Memphis

Mon 5/5

7:39 pm-10:12 am

1 stop13h 33m

Charlotte Douglas

Fri 5/9

6:34 pm-4:19 pm

1 stop22h 45m

$173

MemphisMyrtle Beach

MEM - MYR

MEMMYR

Memphis

Sat 5/10

5:14 pm-10:59 am

1 stop16h 45m

Myrtle Beach Intl

Mon 5/12

7:25 pm-4:19 pm

1 stop21h 54m

$182

MemphisCharleston

MEM - CHS

MEMCHS

Memphis

Thu 5/1

6:51 pm-9:36 am

1 stop13h 45m

Charleston

Sat 5/3

7:15 pm-7:57 am

1 stop13h 42m

$211

MemphisCharleston

MEM - CHS

MEMCHS

Memphis

Fri 5/9

5:14 pm-8:38 am

2 stops14h 24m

Charleston

Sun 5/11

9:43 am-5:29 pm

1 stop8h 46m

$230

Baton RougeCharleston

BTR - CHS

BTRCHS

Baton Rouge Ryan

Sun 4/20

6:00 am-1:41 pm

1 stop6h 41m

Charleston

Tue 4/29

8:05 am-1:23 pm

1 stop6h 18m

$243

MemphisColumbia

MEM - CAE

MEMCAE

Memphis

Wed 4/16

7:05 am-2:19 pm

1 stop6h 14m

Columbia Metropolitan

Sat 4/19

1:48 pm-6:10 pm

1 stop5h 22m

$248

Baton RougeCharleston

BTR - CHS

BTRCHS

Baton Rouge Ryan

Tue 5/27

4:32 pm-10:04 pm

1 stop4h 32m

Charleston

Tue 6/3

5:15 pm-10:08 pm

1 stop5h 53m

$249

MemphisMyrtle Beach

MEM - MYR

MEMMYR

Memphis

Sat 4/26

7:05 am-1:43 pm

1 stop5h 38m

Myrtle Beach Intl

Tue 4/29

7:02 pm-11:17 pm

1 stop5h 15m

$249

MemphisCharlotte

MEM - CLT

MEMCLT

Memphis

Wed 4/23

7:39 pm-9:36 am

1 stop12h 57m

Charlotte Douglas

Sat 7/26

11:52 am-11:22 am

1 stop24h 30m

$253

MemphisMyrtle Beach

MEM - MYR

MEMMYR

Memphis

Sun 5/25

9:20 am-3:28 pm

1 stop5h 08m

Myrtle Beach Intl

Thu 5/29

7:54 pm-11:44 pm

1 stop4h 50m

$268

Flights are sorted by cheapest round-trip flights first.

Deals found on 4/1

Showing 1-10 of 60 results
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Best time to book a flight from Mississippi to South Carolina

Have a flexible travel schedule? Discover the best time to fly to South Carolina from Mississippi with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Mississippi to South Carolina

What is the cheapest month to book a flight from Mississippi to South Carolina?

Currently, August is the cheapest month in which you can book a flight from Mississippi to South Carolina (average of $217). Flying from Mississippi to South Carolina in March is currently the most expensive (average of $335). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from MS to SC?

Find hourly flight availability from Mississippi to South Carolina. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated April 1, 2025.

Regardless of the time of day you decide to fly, the ticket price will remain around the same. Book flights from Mississippi to South Carolina as you normally would.

Rainfall in South Carolina by month

Plan your trip to South Carolina by taking into account the average rainfall totals by month.

In terms of precipitation, rainfall in South Carolina ranges from 3.0 - 6.5 inches per month. July is typically the wettest month, when rainfall can reach 6.5 in. November is typically the driest time to visit South Carolina when rainfall is around 3.0 in.

Temperature in South Carolina by month

Plan your trip to South Carolina by taking into account the average temperature totals by month.

If weather is an important factor for your trip to South Carolina, use this chart to help with planning. For those seeking warmer temperatures, July is the ideal time of year to visit, when temperatures reach an average of 78.8 F. Travelers looking to avoid the cold should look outside of January, when temperatures are typically at their lowest (around 44.6 F).

Reviews of airlines servicing South Carolina

Get insights into the airlines that provide service to South Carolina. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to South Carolina. Reviews last updated April 1, 2025.
Read through reviews of airlines operating flights from Mississippi to South Carolina, such as Breeze Airways, Southwest and Delta. You can also see how each airline compares in terms of entertainment options, comfort, food, crew/service, and boarding process.

Boarding

8.3

Entertainment

6.6

Crew

8.8

Comfort

8.2

Food

6.7

Overall

8.1

Reviews

1 / 11
10.0
Excellent

Dena,Dec 2024

LAS - BDL

It was comfortable and the crew was great! A few free snacks offered would be nice!

Boarding

8.3

Entertainment

6.6

Crew

8.8

Comfort

8.2

Food

6.7

Overall

8.1

Reviews

1 / 11
10.0
Excellent

Dena,Dec 2024

LAS - BDL

It was comfortable and the crew was great! A few free snacks offered would be nice!

Boarding

8.3

Entertainment

6.6

Crew

8.8

Comfort

8.2

Food

6.7

Overall

8.1

Reviews

1 / 11
10.0
Excellent

Dena,Dec 2024

LAS - BDL

It was comfortable and the crew was great! A few free snacks offered would be nice!
8.0
Very good

Boarding

8.3

Entertainment

6.6

Crew

8.8

Comfort

8.2

Food

6.7

Overall

8.1

Reviews

1 / 11
10.0
Excellent

Dena,Dec 2024

LAS - BDL

It was comfortable and the crew was great! A few free snacks offered would be nice!

Boarding

8.3

Entertainment

6.6

Crew

8.8

Comfort

8.2

Food

6.7

Overall

8.1

Reviews

1 / 11
10.0
Excellent

Dena,Dec 2024

LAS - BDL

It was comfortable and the crew was great! A few free snacks offered would be nice!

Boarding

8.3

Entertainment

6.6

Crew

8.8

Comfort

8.2

Food

6.7

Overall

8.1

Reviews

1 / 11
10.0
Excellent

Dena,Dec 2024

LAS - BDL

It was comfortable and the crew was great! A few free snacks offered would be nice!

Related info for your journey

Find useful and relevant information for your journey from Mississippi to South Carolina. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
  • What are the cheapest airlines to fly from Mississippi to South Carolina one-way?

    For one-way options, check prices for Spirit Airlines. According to our data, you can fly for as low as $73. Users have also found prices from $129 and $139 on United Airlines and Frontier, respectively.

  • Can I find deals for flights from Mississippi to South Carolina that include hotel bookings?

    Yes. In addition to deals on Mississippi to South Carolina flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Mississippi to South Carolina?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Mississippi to South Carolina.

  • Can I find deals for business class flights from Mississippi to South Carolina?

    Yes. Cheapflights offers flight deals from Mississippi to South Carolina by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Mississippi to South Carolina?

    Currently, August is the cheapest month in which you can book a flight from Mississippi to South Carolina (average of $217). Flying from Mississippi to South Carolina in March is currently the most expensive (average of $335). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Browse thousands of different options on Cheapflights for your next trip

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Alternative routes for Mississippi to South Carolina

See prices for flight routes from nearby airports that may be better suited for you.

Top 2 airlines flying from Mississippi to South Carolina

Discover the top 2 airlines that operate flights from Mississippi to South Carolina. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated April 1, 2025.
AirlineCheapestAverageFlexibilityOn-time
American AirlinesCheapest$198Average$409FlexibilityNo cancel feeOn-time71%
DeltaCheapest$206Average$436FlexibilityNo cancel feeOn-timeN/A

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