HomeSearch by dateVacation packagesHotelsFlight dealsCar rentalTravel tips & news
South Carolina

$68+ Cheap flights from Minneapolis (MSP) to South Carolina

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 5/2. Fares are subject to change and may not be available on all flights or dates of travel.
MSP — CHS
Apr 9 — Apr 161
Wed 4/9
Wed 4/16
1 adult, Economy
We work with more than 300 partners to bring you better travel deals

Find cheap flights from Minneapolis to South Carolina with Cheapflights

1. Tell us where you want to go

Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”

2. Select your favorite providers

We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.

3. Compare prices and book

Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.

Cheap flight deals from Minneapolis to South Carolina

Keep the following information in mind while searching for Minneapolis to South Carolina flight deals. Data was last updated April 4, 2025.

Most accurate provider

FlightHub
3 stars

Most trusted provider

FlightHub
3 stars

Round-trip from

$147
(FlightHub)

One-way from

$68
(Cheapflightsfares)

Popular in

March

Cheapest in

July

Average price

$268

Good round-trip deal

$239 or less

Good one-way deal

$73 or less
Provider with most accurate pricing for Minneapolis St Paul-Myrtle Beach Intl flight deals.
Search Deals
Provider most trusted by Cheapflights users for Minneapolis St Paul-Myrtle Beach Intl flights.
Search Deals
From Minneapolis St Paul to South Carolina
Search Deals
One-way flight from Minneapolis St Paul to South Carolina
Search Deals
Highest demand for flights based on searches. 12% potential increase in price ($43 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 4% potential price decrease ($12 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in April 2025
Search Deals
Price to beat on a round-trip flight from Minneapolis St Paul to South Carolina.
Search Deals
Price to beat on a one-way flight from Minneapolis St Paul to South Carolina.
Search Deals

Find flight deals from Minneapolis to South Carolina

Cheapest flights from Minneapolis to South Carolina
Explore the most affordable flight options available from Minneapolis to South Carolina. Find the lowest fares from popular airlines and budget airlines, with prices last updated on April 4, 2025.

This FlightHub deal was found by Cheapflights users on 4/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure FlightHub is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 7/211:48 pmMSP - CLT
Nonstop2h 31mSun Country Air
Mon 8/46:15 pmCLT - MSP
Nonstop2h 43mSun Country Air
Deal found 4/3$147
This American Airlines deal was found by Cheapflights users on 4/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/76:00 amMSP - HHH
1 stop7h 43mAmerican Airlines
Wed 5/1410:45 amHHH - MSP
1 stop5h 19mAmerican Airlines
Deal found 4/4$159
This Mytrip deal was found by Cheapflights users on 4/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/28:36 amMSP - CLT
Nonstop2h 36mMultiple Airlines
Fri 5/94:32 pmCLT - MSP
1 stop6h 28mMultiple Airlines
Deal found 4/4$171
This Mytrip deal was found by Cheapflights users on 4/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/28:06 amMSP - MYR
Nonstop2h 39mMultiple Airlines
Fri 5/911:36 amMYR - MSP
1 stop11h 13mMultiple Airlines
Deal found 4/3$183
This Delta deal was found by Cheapflights users on 4/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/312:45 pmMSP - CLT
Nonstop2h 25mDelta
Mon 5/57:05 pmCLT - MSP
Nonstop2h 55mDelta
Deal found 4/4$185
This Cheapflightsfares deal was found by Cheapflights users on 4/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/28:06 amMSP - MYR
Nonstop2h 39mSun Country Air
Mon 5/51:15 pmMYR - MSP
Nonstop3h 02mSun Country Air
Deal found 4/3$185
This American Airlines deal was found by Cheapflights users on 4/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/149:54 amMSP - MYR
1 stop6h 45mAmerican Airlines
Sat 5/176:35 pmMYR - MSP
2 stops6h 24mAmerican Airlines
Deal found 4/4$192
This American Airlines deal was found by Cheapflights users on 4/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/166:00 amMSP - CHS
1 stop7h 56mAmerican Airlines
Tue 4/225:10 amCHS - MSP
1 stop4h 58mAmerican Airlines
Deal found 4/4$201
This Mytrip deal was found by Cheapflights users on 4/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 4/74:07 pmMSP - CHS
Nonstop2h 45mMultiple Airlines
Wed 4/97:30 pmCHS - MSP
2 stops28h 55mMultiple Airlines
Deal found 4/3$205
This American Airlines deal was found by Cheapflights users on 4/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/246:33 amMSP - CLT
Nonstop2h 36mAmerican Airlines
Tue 4/297:30 amCLT - MSP
Nonstop2h 38mAmerican Airlines
Deal found 4/3$205
This Sun Country Air deal was found by Cheapflights users on 4/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Sun Country Air is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 4/138:20 amMSP - CHS
Nonstop2h 49mSun Country Air
Thu 4/171:31 pmCHS - MSP
Nonstop3h 07mSun Country Air
Deal found 4/4$208
This Mytrip deal was found by Cheapflights users on 4/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 4/266:00 amMSP - MYR
1 stop11h 07mSpirit Airlines
Tue 4/297:52 pmMYR - MSP
2 stops18h 48mSpirit Airlines
Deal found 4/3$224

Cheapflights Fare Finder

Customize your flight search to find flights from Minneapolis to South Carolina that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated April 4, 2025.
Use the filters below to find and compare flights from Minneapolis to South Carolina that are best for you.

Fly from

Minneapolis

Fly to

South Carolina

Route

Depart

Return

Price

MinneapolisCharlotte

MSP - CLT

MSPCLT

Minneapolis St Paul

Mon 7/21

1:48 pm-5:19 pm

Nonstop2h 31m

Charlotte Douglas

Mon 8/4

6:15 pm-7:58 pm

Nonstop2h 43m

$147

MinneapolisHilton Head Island

MSP - HHH

MSPHHH

Minneapolis St Paul

Wed 5/7

6:00 am-2:43 pm

1 stop7h 43m

Hilton Head Island

Wed 5/14

10:45 am-3:04 pm

1 stop5h 19m

$159

MinneapolisCharlotte

MSP - CLT

MSPCLT

Minneapolis St Paul

Fri 5/2

8:36 am-12:12 pm

Nonstop2h 36m

Charlotte Douglas

Fri 5/9

4:32 pm-10:00 pm

1 stop6h 28m

$171

MinneapolisMyrtle Beach

MSP - MYR

MSPMYR

Minneapolis St Paul

Fri 5/2

8:06 am-11:45 am

Nonstop2h 39m

Myrtle Beach Intl

Fri 5/9

11:36 am-9:49 pm

1 stop11h 13m

$183

MinneapolisCharlotte

MSP - CLT

MSPCLT

Minneapolis St Paul

Sat 5/3

12:45 pm-4:10 pm

Nonstop2h 25m

Charlotte Douglas

Mon 5/5

7:05 pm-9:00 pm

Nonstop2h 55m

$185

MinneapolisMyrtle Beach

MSP - MYR

MSPMYR

Minneapolis St Paul

Fri 5/2

8:06 am-11:45 am

Nonstop2h 39m

Myrtle Beach Intl

Mon 5/5

1:15 pm-3:17 pm

Nonstop3h 02m

$185

MinneapolisMyrtle Beach

MSP - MYR

MSPMYR

Minneapolis St Paul

Wed 5/14

9:54 am-5:39 pm

1 stop6h 45m

Myrtle Beach Intl

Sat 5/17

6:35 pm-11:59 pm

2 stops6h 24m

$192

MinneapolisCharleston

MSP - CHS

MSPCHS

Minneapolis St Paul

Wed 4/16

6:00 am-2:56 pm

1 stop7h 56m

Charleston

Tue 4/22

5:10 am-9:08 am

1 stop4h 58m

$201

MinneapolisCharleston

MSP - CHS

MSPCHS

Minneapolis St Paul

Mon 4/7

4:07 pm-7:52 pm

Nonstop2h 45m

Charleston

Wed 4/9

7:30 pm-11:25 pm

2 stops28h 55m

$205

MinneapolisCharlotte

MSP - CLT

MSPCLT

Minneapolis St Paul

Thu 4/24

6:33 am-10:09 am

Nonstop2h 36m

Charlotte Douglas

Tue 4/29

7:30 am-9:08 am

Nonstop2h 38m

$205

Flights are sorted by cheapest round-trip flights first.

Deals found on 4/3

Showing 1-10 of 60 results
1
2
3
...
6

Best time to book a flight from Minneapolis to South Carolina

Have a flexible travel schedule? Discover the best time to fly to South Carolina from Minneapolis with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Minneapolis to South Carolina

What is the cheapest month to book a flight from Minneapolis to South Carolina?

Currently, August is the cheapest month in which you can book a flight from Minneapolis to South Carolina (average of $217). Flying from Minneapolis to South Carolina in March is currently the most expensive (average of $335). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from MSP to SC?

Find hourly flight availability from Minneapolis to South Carolina. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated April 4, 2025.

Regardless of the time of day you decide to fly, the ticket price will remain around the same. Book flights from Minneapolis to South Carolina as you normally would.

Rainfall in South Carolina by month

Plan your trip to South Carolina by taking into account the average rainfall totals by month.

In terms of precipitation, rainfall in South Carolina ranges from 3.0 - 6.5 inches per month. July is typically the wettest month, when rainfall can reach 6.5 in. November is typically the driest time to visit South Carolina when rainfall is around 3.0 in.

Temperature in South Carolina by month

Plan your trip to South Carolina by taking into account the average temperature totals by month.

If weather is an important factor for your trip to South Carolina, use this chart to help with planning. For those seeking warmer temperatures, July is the ideal time of year to visit, when temperatures reach an average of 78.8 F. Travelers looking to avoid the cold should look outside of January, when temperatures are typically at their lowest (around 44.6 F).

Reviews of airlines servicing South Carolina

Get insights into the airlines that provide service to South Carolina. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to South Carolina. Reviews last updated April 4, 2025.
Read reviews from past customers who have flown Alaska Airlines, Southwest and Delta from Minneapolis to South Carolina. Users have also rated airlines in terms of entertainment options, comfort, food, crew/service, and boarding process.
Alaska Airlines
8.0
Very good
9,837 reviews

Food

7.1

Entertainment

7.1

Crew

8.5

Boarding

8.2

Comfort

7.9

Overall

8.0

Reviews

1 / 20
10.0
Excellent

Cheri,Jan 2025

FAT - SEA

Very friendly. I really liked that they had water for us in cartons not plastic. Impressed with Alaska Airlines, First time I had flown them
Alaska Airlines
8.0
Very good
9,837 reviews
Alaska Airlines
8.0
Very good
9,837 reviews

Food

7.1

Entertainment

7.1

Crew

8.5

Boarding

8.2

Comfort

7.9

Overall

8.0

Reviews

1 / 20
10.0
Excellent

Cheri,Jan 2025

FAT - SEA

Very friendly. I really liked that they had water for us in cartons not plastic. Impressed with Alaska Airlines, First time I had flown them
Southwest
8.0
Very good
4,276 reviews
Alaska Airlines
8.0
Very good
9,837 reviews

Food

7.1

Entertainment

7.1

Crew

8.5

Boarding

8.2

Comfort

7.9

Overall

8.0

Reviews

1 / 20
10.0
Excellent

Cheri,Jan 2025

FAT - SEA

Very friendly. I really liked that they had water for us in cartons not plastic. Impressed with Alaska Airlines, First time I had flown them
Delta
8.0
Very good
7,899 reviews
Alaska Airlines
8.0
Very good
9,837 reviews

Food

7.1

Entertainment

7.1

Crew

8.5

Boarding

8.2

Comfort

7.9

Overall

8.0

Reviews

1 / 20
10.0
Excellent

Cheri,Jan 2025

FAT - SEA

Very friendly. I really liked that they had water for us in cartons not plastic. Impressed with Alaska Airlines, First time I had flown them
United Airlines
7.4
Good
8,618 reviews
Alaska Airlines
8.0
Very good
9,837 reviews

Food

7.1

Entertainment

7.1

Crew

8.5

Boarding

8.2

Comfort

7.9

Overall

8.0

Reviews

1 / 20
10.0
Excellent

Cheri,Jan 2025

FAT - SEA

Very friendly. I really liked that they had water for us in cartons not plastic. Impressed with Alaska Airlines, First time I had flown them
American Airlines
7.2
Good
10,000 reviews
Alaska Airlines
8.0
Very good
9,837 reviews

Food

7.1

Entertainment

7.1

Crew

8.5

Boarding

8.2

Comfort

7.9

Overall

8.0

Reviews

1 / 20
10.0
Excellent

Cheri,Jan 2025

FAT - SEA

Very friendly. I really liked that they had water for us in cartons not plastic. Impressed with Alaska Airlines, First time I had flown them

Related info for your journey

Find useful and relevant information for your journey from Minneapolis to South Carolina. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly from for flights from Minneapolis to South Carolina?

    Located just 7.3 mi from the city center, Minneapolis St Paul (MSP) is the airport most travelers will use when flying to South Carolina from Minneapolis.

  • How popular is this Minneapolis to South Carolina flight route?

    This flight path from Minneapolis St Paul to South Carolina was viewed by 1 users in the past month. Keep an eye out for changes in search interest prior to high and low season.

  • What are the cheapest airlines to fly from Minneapolis to South Carolina one-way?

    For one-way options, check prices for Sun Country Air. According to our data, you can fly for as low as $68. Users have also found prices from $80 and $99 on American Airlines and Spirit Airlines, respectively.

  • What are the most popular routes from Minneapolis to South Carolina?

    While some choose either Minneapolis St Paul - Charlotte Douglas or Minneapolis St Paul - Savannah/Hilton Head, Minneapolis St Paul - Charleston is the most popular route from Minneapolis to South Carolina.

  • What are the most reliable airlines from Minneapolis to South Carolina?

    Looking for the most reliable airlines to get you to your destination on time? Our data shows these are most likely to get you from Minneapolis to South Carolina on time: WestJet (79%), Delta (74%), Endeavor Airlines (74%).

  • What are the cheapest flights from Minneapolis to South Carolina?

    On average you can expect to pay $255 for a flight from Minneapolis to South Carolina. The cheapest flight overall is $72 while the most popular route, (Minneapolis St Paul - Charleston) is currently priced at $146.

  • Can I find deals for flights from Minneapolis to South Carolina that include hotel bookings?

    Yes. In addition to deals on Minneapolis to South Carolina flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Minneapolis to South Carolina?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Minneapolis to South Carolina.

  • Can I find deals for business class flights from Minneapolis to South Carolina?

    Yes. Cheapflights offers flight deals from Minneapolis to South Carolina by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Minneapolis to South Carolina?

    Currently, August is the cheapest month in which you can book a flight from Minneapolis to South Carolina (average of $217). Flying from Minneapolis to South Carolina in March is currently the most expensive (average of $335). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Browse thousands of different options on Cheapflights for your next trip

Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.

Alternative routes for Minneapolis to South Carolina

See prices for flight routes from nearby airports that may be better suited for you.
Minneapolis to Las Vegas flights
Minneapolis to Seattle flights
Minneapolis to Dallas/Fort Worth flights
Minneapolis to LaGuardia flights
Minneapolis to Denver flights
Minneapolis to Orlando flights
Minneapolis to Sky Harbor Intl flights
Minneapolis to Reagan-National flights
Minneapolis to Newark flights
Minneapolis to Boston flights
Minneapolis to John F Kennedy Intl flights
Minneapolis to Fort Myers flights
Minneapolis to Tampa flights
Minneapolis to O'Hare Intl flights
Minneapolis to Dulles Intl flights
Minneapolis to Miami flights
Minneapolis to Los Angeles flights
Minneapolis to Nashville flights
Minneapolis to Fort Lauderdale flights
Minneapolis to Midway flights
Minneapolis to Portland flights
Minneapolis to George Bush Intcntl flights
Minneapolis to Hobby flights
Minneapolis to Austin flights
Minneapolis to San Francisco flights
Minneapolis to Honolulu flights
Minneapolis to Baltimore flights
Minneapolis to Philadelphia flights
Minneapolis to San Diego flights
Minneapolis to Salt Lake City flights
Minneapolis to New Orleans flights
Minneapolis to Atlanta flights
Minneapolis to Charleston flights
Minneapolis to Ontario flights
Minneapolis to Charlotte flights
Minneapolis to Anchorage flights
Minneapolis to Cleveland flights
Minneapolis to Savannah flights
Minneapolis to Bozeman flights
Minneapolis to Sarasota flights
Sioux Falls to Denver flights
Minneapolis to Phoenix-Mesa Gateway flights
Minneapolis to Santa Ana flights
Minneapolis to Love Field flights
Minneapolis to San Antonio flights
Minneapolis to Raleigh flights
Minneapolis to Detroit flights
Minneapolis to Myrtle Beach flights
Fargo to Denver flights
Minneapolis to Pittsburgh flights

Top 6 airlines flying from Minneapolis to South Carolina

Discover the top 6 airlines that operate flights from Minneapolis to South Carolina. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated April 4, 2025.
AirlineCheapestAverageFlexibilityOn-time
Sun Country AirCheapest$68Average$183FlexibilityNo cancel feeOn-time83%
Spirit AirlinesCheapest$117Average$219FlexibilityNo cancel feeOn-time65%
DeltaCheapest$172Average$412FlexibilityNo cancel feeOn-timeN/A
American AirlinesCheapest$178Average$377FlexibilityNo cancel feeOn-time71%
United AirlinesCheapest$207Average$391FlexibilityNo cancel feeOn-time69%
SouthwestCheapest$270Average$407FlexibilityNo cancel feeOn-time63%

100% Free

Cheapflights is completely free to use, so you can start saving the moment you arrive.

Book with Flexibility

Our users can plan ahead with confidence and find flights with no change fees

Travel Smart

Millions of people come to us for their flight needs every year. We help make travel planning easy by providing useful insights and data-driven graphs that can inform your decisions.