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$73+ Cheap flights from Milwaukee (MKE) to South Carolina

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 4/11. Fares are subject to change and may not be available on all flights or dates of travel.
MKE — CHS
feb. 25 — mar. 41
mar. 2/25
mar. 3/4
1 adult, Economy
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Cheap flight deals from Milwaukee to South Carolina

Keep the following information in mind while searching for Milwaukee to South Carolina flight deals. Data was last updated febrero 20, 2025.

Most accurate provider

FlightHub
3 stars

Most trusted provider

FlightHub
3 stars

Round-trip from

$156
(FlightHub)

One-way from

$73
(Mytrip)

Popular in

March

Cheapest in

October

Average price

$348
Provider with most accurate pricing for Milwaukee-Mitchell-Myrtle Beach Intl flight deals.
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Provider most trusted by Cheapflights users for Milwaukee-Mitchell-Myrtle Beach Intl flights.
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From Milwaukee-Mitchell to South Carolina
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One-way flight from Milwaukee-Mitchell to South Carolina
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Highest demand for flights based on searches. 6% potential increase in price ($24 potential increase over avg. RT price).
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Cheapest flight prices on average. 2% potential price decrease ($9 potential savings vs. average RT price).
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Average for round-trip flights in February 2025
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Find flight deals from Milwaukee to South Carolina

Cheapest flights from Milwaukee to South Carolina
Explore the most affordable flight options available from Milwaukee to South Carolina. Find the lowest fares from popular airlines and budget airlines, with prices last updated on febrero 20, 2025.

This FlightHub deal was found by Cheapflights users on 2/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure FlightHub is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
vie. 4/44:05 pmMKE - MYR
1 stop24h 31mSpirit Airlines
lun. 4/710:27 pmMYR - MKE
1 stop12h 12mSpirit Airlines
Deal found 2/20$156
This Booking.com deal was found by Cheapflights users on 2/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Booking.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
vie. 4/113:52 pmMKE - CLT
1 stop14h 06mMultiple Airlines
mié. 4/1610:57 amCLT - MKE
1 stop5h 49mMultiple Airlines
Deal found 2/19$157
This FlightHub deal was found by Cheapflights users on 2/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure FlightHub is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mar. 4/221:00 pmMKE - CLT
1 stop8h 38mSpirit Airlines
jue. 4/247:00 amCLT - MKE
1 stop10h 05mSpirit Airlines
Deal found 2/20$160
This Mytrip deal was found by Cheapflights users on 2/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mié. 4/167:48 pmMKE - CHS
2 stops13h 20mSpirit Airlines
mié. 4/237:40 pmCHS - MKE
1 stop21h 25mSpirit Airlines
Deal found 2/20$160
This Booking.com deal was found by Cheapflights users on 2/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Booking.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
vie. 3/71:19 pmMKE - CLT
1 stop16h 34mFrontier
lun. 3/107:38 pmCLT - MKE
1 stop17h 41mFrontier
Deal found 2/19$170
This Mytrip deal was found by Cheapflights users on 2/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
lun. 4/74:05 pmMKE - SAV
1 stop6h 08mMultiple Airlines
vie. 4/1112:34 pmSAV - MKE
2 stops28h 12mMultiple Airlines
Deal found 2/20$213
This American Airlines deal was found by Cheapflights users on 2/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
vie. 3/146:24 pmMKE - AGS
1 stop4h 23mAmerican Airlines
lun. 3/177:18 amAGS - MKE
1 stop5h 09mAmerican Airlines
Deal found 2/20$237
This Mytrip deal was found by Cheapflights users on 2/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
lun. 3/105:34 pmMKE - CHS
2 stops19h 30mMultiple Airlines
jue. 3/137:05 amCHS - MKE
3 stops34h 34mMultiple Airlines
Deal found 2/19$246
This Delta deal was found by Cheapflights users on 2/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
sáb. 10/182:45 pmMKE - CAE
1 stop4h 42mDelta
mar. 10/216:50 pmCAE - MKE
1 stop5h 35mDelta
Deal found 2/18$249
This Delta deal was found by Cheapflights users on 2/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
lun. 5/126:40 pmMKE - SAV
1 stop4h 24mDelta
mar. 5/205:30 amSAV - MKE
1 stop6h 44mDelta
Deal found 2/19$257
This Delta deal was found by Cheapflights users on 2/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
jue. 4/1712:38 pmMKE - AGS
1 stop6h 50mDelta
mar. 4/227:25 pmAGS - MKE
1 stop5h 29mDelta
Deal found 2/20$258
This American Airlines deal was found by Cheapflights users on 2/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mié. 4/26:27 pmMKE - SAV
1 stop4h 23mAmerican Airlines
mié. 4/95:05 amSAV - MKE
2 stops7h 36mAmerican Airlines
Deal found 2/20$262

Find flights from Milwaukee to South Carolina within your budget

Customize your flight search to find flights from Milwaukee to South Carolina that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated febrero 20, 2025.

Fly from

Milwaukee

Fly to

South Carolina

Route

Depart

Return

Price

MilwaukeeMyrtle Beach

MKE - MYR

MKEMYR

Milwaukee-Mitchell

vie. 4/4

4:05 pm-5:36 pm

1 stop24h 31m

Myrtle Beach Intl

lun. 4/7

10:27 pm-9:39 am

1 stop12h 12m

$156

MilwaukeeCharlotte

MKE - CLT

MKECLT

Milwaukee-Mitchell

vie. 4/11

4:02 pm-7:58 am

1 stop14h 56m

Charlotte Douglas

mié. 4/16

10:57 am-3:46 pm

1 stop5h 49m

$157

MilwaukeeCharlotte

MKE - CLT

MKECLT

Milwaukee-Mitchell

mar. 4/22

1:00 pm-10:38 pm

1 stop8h 38m

Charlotte Douglas

jue. 4/24

7:00 am-4:05 pm

1 stop10h 05m

$160

MilwaukeeCharleston

MKE - CHS

MKECHS

Milwaukee-Mitchell

mié. 4/16

7:48 pm-10:08 am

2 stops13h 20m

Charleston

mié. 4/23

7:40 pm-4:05 pm

1 stop21h 25m

$160

MilwaukeeCharlotte

MKE - CLT

MKECLT

Milwaukee-Mitchell

vie. 3/7

1:19 pm-6:53 am

1 stop16h 34m

Charlotte Douglas

lun. 3/10

7:38 pm-12:19 pm

1 stop17h 41m

$170

MilwaukeeSavannah

MKE - SAV

MKESAV

Milwaukee-Mitchell

lun. 4/7

4:05 pm-11:13 pm

1 stop6h 08m

Savannah/Hilton Head

vie. 4/11

12:34 pm-3:46 pm

2 stops28h 12m

$213

MilwaukeeAugusta

MKE - AGS

MKEAGS

Milwaukee-Mitchell

vie. 3/14

6:24 pm-11:47 pm

1 stop4h 23m

Augusta Bush Field

lun. 3/17

7:18 am-11:27 am

1 stop5h 09m

$237

MilwaukeeCharleston

MKE - CHS

MKECHS

Milwaukee-Mitchell

lun. 3/10

5:34 pm-2:04 pm

2 stops19h 30m

Charleston

jue. 3/13

7:05 am-4:39 pm

3 stops34h 34m

$246

MilwaukeeSavannah

MKE - SAV

MKESAV

Milwaukee-Mitchell

lun. 5/12

6:40 pm-12:04 am

1 stop4h 24m

Savannah/Hilton Head

mié. 5/21

5:30 am-11:14 am

1 stop6h 44m

$257

MilwaukeeCharleston

MKE - CHS

MKECHS

Milwaukee-Mitchell

mié. 4/16

12:11 pm-7:00 pm

1 stop5h 49m

Charleston

mié. 4/23

3:53 pm-10:58 pm

1 stop8h 05m

$257

Flights are sorted by cheapest round-trip flights first.

Deals found on 2/19

Showing 1-10 of 59 results
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Best time to book a flight from Milwaukee to South Carolina

Have a flexible travel schedule? Discover the best time to fly to South Carolina from Milwaukee with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Travel insights for flights from Milwaukee to South Carolina

Get recent, data-driven insights about flights from Milwaukee to South Carolina including ideal travel times, pricing trends, and more.

What is the cheapest month to book a flight from Milwaukee to South Carolina?

Currently, August is the cheapest month in which you can book a flight from Milwaukee to South Carolina (average of $217). Flying from Milwaukee to South Carolina in March is currently the most expensive (average of $335). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from MKE to SC?

Find hourly flight availability from Milwaukee to South Carolina. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated febrero 20, 2025.

When flying from Milwaukee to South Carolina, the time of day you decide to fly out makes little to no difference towards the overall price you’ll pay on tickets.

Rainfall in South Carolina by month

Plan your trip to South Carolina by taking into account the average rainfall totals by month.

In terms of precipitation, rainfall in South Carolina ranges from 3.0 - 6.5 inches per month. July is typically the wettest month, when rainfall can reach 6.5 in. November is typically the driest time to visit South Carolina when rainfall is around 3.0 in.

Temperature in South Carolina by month

Plan your trip to South Carolina by taking into account the average temperature totals by month.

If weather is an important factor for your trip to South Carolina, use this chart to help with planning. For those seeking warmer temperatures, July is the ideal time of year to visit, when temperatures reach an average of 78.8 F. Travelers looking to avoid the cold should look outside of January, when temperatures are typically at their lowest (around 44.6 F).

Reviews of airlines servicing South Carolina

Get insights into the airlines that provide service to South Carolina. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to South Carolina. Reviews last updated febrero 20, 2025.
To help decide which airline to fly from Milwaukee to South Carolina, see what other customers have to say about Southwest, Delta and United Airlines. Users can see the overall rating for each airline as well as how each is rated in terms of entertainment options, comfort, food, crew/service, and boarding process.
Southwest
8.1
Very good
4,411 reviews

Entertainment

7.6

Boarding

8.2

Food

7.1

Comfort

8.1

Overall

8.1

Crew

8.7

Reviews

1 / 20

2.0
Mediocre

Anonymous,Feb 2025

MCO - STL

Cancelled at last minute, SWA unable to assist in formulating alternate plans. Wound up renting a car and driving 13 hours to beat bad weather forecast at home. Not SWA’s fault that there was significant bad weather across the country.

Southwest
8.1
Very good
4,411 reviews
Southwest
8.1
Very good
4,411 reviews

Entertainment

7.6

Boarding

8.2

Food

7.1

Comfort

8.1

Overall

8.1

Crew

8.7

Reviews

1 / 20

2.0
Mediocre

Anonymous,Feb 2025

MCO - STL

Cancelled at last minute, SWA unable to assist in formulating alternate plans. Wound up renting a car and driving 13 hours to beat bad weather forecast at home. Not SWA’s fault that there was significant bad weather across the country.

Delta
8.0
Very good
8,220 reviews
Southwest
8.1
Very good
4,411 reviews

Entertainment

7.6

Boarding

8.2

Food

7.1

Comfort

8.1

Overall

8.1

Crew

8.7

Reviews

1 / 20

2.0
Mediocre

Anonymous,Feb 2025

MCO - STL

Cancelled at last minute, SWA unable to assist in formulating alternate plans. Wound up renting a car and driving 13 hours to beat bad weather forecast at home. Not SWA’s fault that there was significant bad weather across the country.

United Airlines
7.4
Good
8,766 reviews
Southwest
8.1
Very good
4,411 reviews

Entertainment

7.6

Boarding

8.2

Food

7.1

Comfort

8.1

Overall

8.1

Crew

8.7

Reviews

1 / 20

2.0
Mediocre

Anonymous,Feb 2025

MCO - STL

Cancelled at last minute, SWA unable to assist in formulating alternate plans. Wound up renting a car and driving 13 hours to beat bad weather forecast at home. Not SWA’s fault that there was significant bad weather across the country.

American Airlines
7.2
Good
10,000 reviews
Southwest
8.1
Very good
4,411 reviews

Entertainment

7.6

Boarding

8.2

Food

7.1

Comfort

8.1

Overall

8.1

Crew

8.7

Reviews

1 / 20

2.0
Mediocre

Anonymous,Feb 2025

MCO - STL

Cancelled at last minute, SWA unable to assist in formulating alternate plans. Wound up renting a car and driving 13 hours to beat bad weather forecast at home. Not SWA’s fault that there was significant bad weather across the country.

Sun Country Air
7.0
Good
374 reviews
Southwest
8.1
Very good
4,411 reviews

Entertainment

7.6

Boarding

8.2

Food

7.1

Comfort

8.1

Overall

8.1

Crew

8.7

Reviews

1 / 20

2.0
Mediocre

Anonymous,Feb 2025

MCO - STL

Cancelled at last minute, SWA unable to assist in formulating alternate plans. Wound up renting a car and driving 13 hours to beat bad weather forecast at home. Not SWA’s fault that there was significant bad weather across the country.

Related info for your journey

Find useful and relevant information for your journey from Milwaukee to South Carolina. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly from for flights from Milwaukee to South Carolina?

    Milwaukee-Mitchell (MKE), located 6.4 mi from the city center, is the airport you fly out of when you book flights from Milwaukee to South Carolina.

  • What are the cheapest airlines to fly from Milwaukee to South Carolina one-way?

    For one-way options, check prices for Frontier. According to our data, you can fly for as low as $73. Users have also found prices from $78 and $129 on Spirit Airlines and American Airlines, respectively.

  • What are the most popular routes from Milwaukee to South Carolina?

    While some choose either Milwaukee-Mitchell - Savannah/Hilton Head or Milwaukee-Mitchell - Charleston, Milwaukee-Mitchell - Charlotte Douglas is the most popular route from Milwaukee to South Carolina.

  • Can I find deals for flights from Milwaukee to South Carolina that include hotel bookings?

    Yes. In addition to deals on Milwaukee to South Carolina flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Milwaukee to South Carolina?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Milwaukee to South Carolina.

  • Can I find deals for business class flights from Milwaukee to South Carolina?

    Yes. Cheapflights offers flight deals from Milwaukee to South Carolina by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Milwaukee to South Carolina?

    Currently, August is the cheapest month in which you can book a flight from Milwaukee to South Carolina (average of $217). Flying from Milwaukee to South Carolina in March is currently the most expensive (average of $335). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

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Alternative routes for Milwaukee to South Carolina

See prices for flight routes from nearby airports that may be better suited for you.
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Top 5 airlines flying from Milwaukee to South Carolina

Discover the top 5 airlines that operate flights from Milwaukee to South Carolina. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated febrero 20, 2025.
AirlineCheapestAverageFlexibilityOn-time
Spirit AirlinesCheapest$155Average$267FlexibilityNo cancel feeOn-time65%
United AirlinesCheapest$213Average$393FlexibilityNo cancel feeOn-time69%
DeltaCheapest$216Average$384FlexibilityNo cancel feeOn-timeN/A
American AirlinesCheapest$216Average$367FlexibilityNo cancel feeOn-time71%
SouthwestCheapest$296Average$404FlexibilityNo cancel feeOn-time63%
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