HomeSearch by dateVacation packagesHotelsFlight dealsCar rentalTravel tips & news
South Carolina

$60+ Cheap flights from Milwaukee (MKE) to South Carolina

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 12/17. Fares are subject to change and may not be available on all flights or dates of travel.
MKE — CHS
Nov 25 — Dec 21
Mon 11/25
Mon 12/2
1 adult, Economy
We work with more than 300 partners to bring you better travel deals

Find cheap flights from Milwaukee to South Carolina with Cheapflights

1. Tell us where you want to go
Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”
2. Select your favorite providers
We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.
3. Compare prices and book
Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.

Cheap flight deals from Milwaukee to South Carolina

Discover tips and strategies to find the most affordable flight options for your journey from Milwaukee (MKE) to South Carolina (USSC). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated November 20, 2024.

Find flight deals from Milwaukee to South Carolina

Cheapest flights from Milwaukee to South Carolina
Explore the most affordable flight options available from Milwaukee to South Carolina. Find the lowest fares from popular airlines and budget airlines, with prices last updated on November 20, 2024.

This Frontier deal was found by Cheapflights users on 11/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/1310:47 amMKE - CLT
1 stop5h 47mFrontier
Tue 12/178:51 amCLT - MKE
1 stop11h 49mFrontier
Deal found 11/20$138
This Mytrip deal was found by Cheapflights users on 11/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/65:00 amMKE - CHS
1 stop12h 49mSpirit Airlines
Sat 12/75:14 pmCHS - MKE
1 stop6h 31mSpirit Airlines
Deal found 11/19$165
This Mytrip deal was found by Cheapflights users on 11/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/65:00 amMKE - CLT
1 stop15h 47mSpirit Airlines
Tue 12/102:40 pmCLT - MKE
1 stop8h 02mSpirit Airlines
Deal found 11/19$169
This FlightHub deal was found by Cheapflights users on 11/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure FlightHub is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/125:00 amMKE - CLT
1 stop13h 53mMultiple Airlines
Tue 12/176:40 pmCLT - MKE
1 stop20h 16mMultiple Airlines
Deal found 11/19$183
This Mytrip deal was found by Cheapflights users on 11/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/115:00 amMKE - MYR
1 stop10h 41mSpirit Airlines
Mon 12/1611:04 amMYR - MKE
1 stop11h 38mSpirit Airlines
Deal found 11/19$191
This Mytrip deal was found by Cheapflights users on 11/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/165:00 amMKE - SAV
1 stop16h 26mMultiple Airlines
Mon 12/2311:47 amSAV - MKE
1 stop11h 58mMultiple Airlines
Deal found 11/20$208
This Mytrip deal was found by Cheapflights users on 11/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/65:00 amMKE - CHS
1 stop12h 49mMultiple Airlines
Mon 12/99:31 pmCHS - MKE
2 stops25h 11mMultiple Airlines
Deal found 11/19$220
This Delta deal was found by Cheapflights users on 11/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/42:20 pmMKE - CAE
1 stop7h 53mDelta
Sat 12/78:15 amCAE - MKE
1 stop6h 16mDelta
Deal found 11/19$258
This American Airlines deal was found by Cheapflights users on 11/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/45:50 amMKE - CAE
1 stop8h 43mAmerican Airlines
Sat 12/75:15 amCAE - MKE
2 stops7h 08mAmerican Airlines
Deal found 11/19$263
This Delta deal was found by Cheapflights users on 11/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/256:00 amMKE - CLT
1 stop6h 29mDelta
Fri 11/2910:00 amCLT - MKE
1 stop4h 35mDelta
Deal found 11/18$278
This Delta deal was found by Cheapflights users on 11/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/105:45 amMKE - GSP
1 stop4h 19mDelta
Tue 12/1712:36 pmGSP - MKE
1 stop8h 17mDelta
Deal found 11/20$286
This American Airlines deal was found by Cheapflights users on 11/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/186:54 amMKE - CLT
Nonstop2h 11mAmerican Airlines
Wed 12/254:17 pmCLT - MKE
Nonstop2h 03mAmerican Airlines
Deal found 11/20$290

Find flights from Milwaukee to South Carolina within your budget

Customize your flight search to find flights from Milwaukee to South Carolina that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,629,791 searches. Data last updated November 20, 2024.

Fly from

Any airport

Fly to

Any airport

Route

Depart

Return

Price

MilwaukeeCharlotte

MKE - CLT

MKECLT

Milwaukee-Mitchell

Fri 12/13

10:47 am-5:34 pm

1 stop5h 47m

Charlotte Douglas

Tue 12/17

8:51 am-7:40 pm

1 stop11h 49m

$138

MilwaukeeCharleston

MKE - CHS

MKECHS

Milwaukee-Mitchell

Fri 12/6

5:00 am-6:49 pm

1 stop12h 49m

Charleston

Sat 12/7

5:14 pm-10:45 pm

1 stop6h 31m

$165

MilwaukeeCharlotte

MKE - CLT

MKECLT

Milwaukee-Mitchell

Fri 12/6

5:00 am-9:47 pm

1 stop15h 47m

Charlotte Douglas

Tue 12/10

2:40 pm-9:42 pm

1 stop8h 02m

$169

MilwaukeeCharlotte

MKE - CLT

MKECLT

Milwaukee-Mitchell

Thu 12/12

5:00 am-7:53 pm

1 stop13h 53m

Charlotte Douglas

Tue 12/17

6:40 pm-1:56 pm

1 stop20h 16m

$183

MilwaukeeMyrtle Beach

MKE - MYR

MKEMYR

Milwaukee-Mitchell

Wed 12/11

5:00 am-4:41 pm

1 stop10h 41m

Myrtle Beach Intl

Mon 12/16

11:04 am-9:42 pm

1 stop11h 38m

$191

MilwaukeeSavannah

MKE - SAV

MKESAV

Milwaukee-Mitchell

Mon 12/16

5:00 am-10:26 pm

1 stop16h 26m

Savannah/Hilton Head

Mon 12/23

11:47 am-10:45 pm

1 stop11h 58m

$208

MilwaukeeCharleston

MKE - CHS

MKECHS

Milwaukee-Mitchell

Fri 12/6

5:00 am-6:49 pm

1 stop12h 49m

Charleston

Mon 12/9

9:31 pm-9:42 pm

2 stops25h 11m

$220

MilwaukeeColumbia

MKE - CAE

MKECAE

Milwaukee-Mitchell

Thu 2/20

6:35 am-4:02 pm

1 stop8h 27m

Columbia Metropolitan

Mon 2/24

6:00 am-12:18 pm

1 stop7h 18m

$248

MilwaukeeHilton Head Island

MKE - HHH

MKEHHH

Milwaukee-Mitchell

Sun 1/5

6:00 am-2:12 pm

1 stop7h 12m

Hilton Head Island

Sun 1/12

6:05 pm-9:52 pm

1 stop4h 47m

$254

MilwaukeeColumbia

MKE - CAE

MKECAE

Milwaukee-Mitchell

Wed 12/4

5:50 am-3:33 pm

1 stop8h 43m

Columbia Metropolitan

Sat 12/7

5:15 am-11:23 am

2 stops7h 08m

$263

Flights are sorted by cheapest round-trip flights first.

Deals found on 11/19

Showing 1-10 of 51 results
1
2
3
...
6

Best time to book a flight from Milwaukee to South Carolina

Have a flexible travel schedule? Discover the best time to fly to South Carolina from Milwaukee with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Travel insights for flights from Milwaukee to South Carolina

Get recent, data-driven insights about flights from Milwaukee to South Carolina including ideal travel times, pricing trends, and more.

What is the cheapest month to book a flight from Milwaukee to South Carolina?

Currently, August is the cheapest month in which you can book a flight from Milwaukee to South Carolina (average of $217). Flying from Milwaukee to South Carolina in April is currently the most expensive (average of $314). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from MKE to SC?

Find hourly flight availability from Milwaukee to South Carolina. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated November 20, 2024.

When flying from Milwaukee to South Carolina, the time of day you decide to fly out makes little to no difference towards the overall price you’ll pay on tickets.

Rainfall in South Carolina by month

Plan your trip to South Carolina by taking into account the average rainfall totals by month.

In terms of precipitation, rainfall in South Carolina ranges from 3.0 - 6.5 inches per month. July is typically the wettest month, when rainfall can reach 6.5 in. November is typically the driest time to visit South Carolina when rainfall is around 3.0 in.

Temperature in South Carolina by month

Plan your trip to South Carolina by taking into account the average temperature totals by month.

If weather is an important factor for your trip to South Carolina, use this chart to help with planning. For those seeking warmer temperatures, July is the ideal time of year to visit, when temperatures reach an average of 78.8 F. Travelers looking to avoid the cold should look outside of January, when temperatures are typically at their lowest (around 44.6 F).

Reviews of airlines servicing South Carolina

Get insights into the airlines that provide service to South Carolina. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to South Carolina. Reviews last updated November 20, 2024.
To help decide which airline to fly from Milwaukee to South Carolina, see what other customers have to say about Delta, Frontier and Southwest. Users can see the overall rating for each airline as well as how each is rated in terms of entertainment options, comfort, food, crew/service, and boarding process.
Southwest
8.1
Very good
5,014 reviews

Overall

8.1

Crew

8.7

Comfort

8.1

Boarding

8.2

Entertainment

7.7

Food

7.2

Reviews

1 / 10

Great service throughout our flight. Easy boarding with early bird check in

Southwest
8.1
Very good
5,014 reviews
Southwest
8.1
Very good
5,014 reviews

Overall

8.1

Crew

8.7

Comfort

8.1

Boarding

8.2

Entertainment

7.7

Food

7.2

Reviews

1 / 10

Great service throughout our flight. Easy boarding with early bird check in

Delta
8.0
Very good
8,756 reviews
Southwest
8.1
Very good
5,014 reviews

Overall

8.1

Crew

8.7

Comfort

8.1

Boarding

8.2

Entertainment

7.7

Food

7.2

Reviews

1 / 10

Great service throughout our flight. Easy boarding with early bird check in

United Airlines
7.4
Good
9,171 reviews
Southwest
8.1
Very good
5,014 reviews

Overall

8.1

Crew

8.7

Comfort

8.1

Boarding

8.2

Entertainment

7.7

Food

7.2

Reviews

1 / 10

Great service throughout our flight. Easy boarding with early bird check in

WestJet
7.3
Good
2,811 reviews
Southwest
8.1
Very good
5,014 reviews

Overall

8.1

Crew

8.7

Comfort

8.1

Boarding

8.2

Entertainment

7.7

Food

7.2

Reviews

1 / 10

Great service throughout our flight. Easy boarding with early bird check in

American Airlines
7.2
Good
10,000 reviews
Southwest
8.1
Very good
5,014 reviews

Overall

8.1

Crew

8.7

Comfort

8.1

Boarding

8.2

Entertainment

7.7

Food

7.2

Reviews

1 / 10

Great service throughout our flight. Easy boarding with early bird check in

Related info for your journey

Find useful and relevant information for your journey from Milwaukee to South Carolina. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly from for flights from Milwaukee to South Carolina?

    Milwaukee-Mitchell (MKE), located 6.4 mi from the city center, is the airport you fly out of when you book flights from Milwaukee to South Carolina.

  • What are the cheapest airlines to fly from Milwaukee to South Carolina one-way?

    For one-way options, check prices for Frontier. According to our data, you can fly for as low as $60. Users have also found prices from $76 and $139 on Spirit Airlines and Delta, respectively.

  • What are the most popular routes from Milwaukee to South Carolina?

    While some choose either Milwaukee-Mitchell - Charleston or Milwaukee-Mitchell - Savannah/Hilton Head, Milwaukee-Mitchell - Charlotte Douglas is the most popular route from Milwaukee to South Carolina.

  • Can I find deals for flights from Milwaukee to South Carolina that include hotel bookings?

    Yes. In addition to deals on Milwaukee to South Carolina flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Milwaukee to South Carolina?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Milwaukee to South Carolina.

  • Can I find deals for business class flights from Milwaukee to South Carolina?

    Yes. Cheapflights offers flight deals from Milwaukee to South Carolina by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Milwaukee to South Carolina?

    Currently, August is the cheapest month in which you can book a flight from Milwaukee to South Carolina (average of $217). Flying from Milwaukee to South Carolina in April is currently the most expensive (average of $314). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Browse thousands of different options on Cheapflights for your next trip

Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.

Alternative routes for Milwaukee to South Carolina

See prices for flight routes from nearby airports that may be better suited for you.
O'Hare Intl to Orlando flights
O'Hare Intl to Miami flights
O'Hare Intl to Dallas/Fort Worth flights
O'Hare Intl to John F Kennedy Intl flights
O'Hare Intl to Los Angeles flights
O'Hare Intl to Fort Lauderdale flights
O'Hare Intl to LaGuardia flights
O'Hare Intl to Sky Harbor Intl flights
O'Hare Intl to Las Vegas flights
Minneapolis to Las Vegas flights
O'Hare Intl to Newark flights
Minneapolis to Sky Harbor Intl flights
Minneapolis to Orlando flights
O'Hare Intl to Tampa flights
O'Hare Intl to Denver flights
O'Hare Intl to Seattle flights
O'Hare Intl to Atlanta flights
Minneapolis to Newark flights
Minneapolis to LaGuardia flights
O'Hare Intl to Hobby flights
O'Hare Intl to Boston flights
Minneapolis to Fort Myers flights
Minneapolis to Seattle flights
O'Hare Intl to Honolulu flights
O'Hare Intl to San Francisco flights
Minneapolis to Miami flights
O'Hare Intl to New Orleans flights
Minneapolis to Los Angeles flights
O'Hare Intl to George Bush Intcntl flights
O'Hare Intl to San Diego flights
O'Hare Intl to Fort Myers flights
Minneapolis to Dallas/Fort Worth flights
Minneapolis to Fort Lauderdale flights
O'Hare Intl to Santa Ana flights
Minneapolis to Tampa flights
Minneapolis to John F Kennedy Intl flights
O'Hare Intl to Baltimore flights
O'Hare Intl to Dulles Intl flights
O'Hare Intl to West Palm Beach flights
O'Hare Intl to Burbank flights
Minneapolis to O'Hare Intl flights
O'Hare Intl to Ontario flights
O'Hare Intl to Nashville flights
O'Hare Intl to Philadelphia flights
O'Hare Intl to Reagan-National flights
Milwaukee to LaGuardia flights
Minneapolis to San Diego flights
Minneapolis to Denver flights
O'Hare Intl to Salt Lake City flights
O'Hare Intl to Austin flights

Top 5 airlines flying from Milwaukee to South Carolina

Discover the top 5 airlines that operate flights from Milwaukee to South Carolina. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,629,791 searches. Data last updated November 20, 2024.
AirlineCheapestAverageFlexibilityOn-time
American AirlinesCheapest$153Average$360FlexibilityNo cancel feeOn-time71%
Spirit AirlinesCheapest$155Average$257FlexibilityNo cancel feeOn-time65%
DeltaCheapest$216Average$384FlexibilityNo cancel feeOn-timeN/A
United AirlinesCheapest$256Average$398FlexibilityNo cancel feeOn-time69%
SouthwestCheapest$282Average$356FlexibilityNo cancel feeOn-time63%
100% Free
Cheapflights is completely free to use, so you can start saving the moment you arrive.
Book with Flexibility
Our users can plan ahead with confidence and find flights with no change fees
Travel Smart
Millions of people come to us for their flight needs every year. We help make travel planning easy by providing useful insights and data-driven graphs that can inform your decisions.
View all available airlines