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South Carolina

$79+ Cheap flights from Milwaukee (MKE) to South Carolina

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 5/14. Fares are subject to change and may not be available on all flights or dates of travel.
MKE — CHS
Apr 2 — Apr 91
Wed 4/2
Wed 4/9
1 adult, Economy
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Cheap flight deals from Milwaukee to South Carolina

Keep the following information in mind while searching for Milwaukee to South Carolina flight deals. Data was last updated March 28, 2025.

Most accurate provider

FlightHub
3 stars

Most trusted provider

FlightHub
3 stars

Round-trip from

$155
(Mytrip)

One-way from

$79
(Booking.com)

Popular in

March

Cheapest in

October

Average price

$558
Provider with most accurate pricing for Milwaukee-Mitchell-Myrtle Beach Intl flight deals.
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Provider most trusted by Cheapflights users for Milwaukee-Mitchell-Myrtle Beach Intl flights.
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From Milwaukee-Mitchell to South Carolina
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One-way flight from Milwaukee-Mitchell to South Carolina
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Highest demand for flights based on searches. 11% potential increase in price ($50 potential increase over avg. RT price).
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Cheapest flight prices on average. 4% potential price decrease ($17 potential savings vs. average RT price).
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Average for round-trip flights in March 2025
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Find flight deals from Milwaukee to South Carolina

Cheapest flights from Milwaukee to South Carolina
Explore the most affordable flight options available from Milwaukee to South Carolina. Find the lowest fares from popular airlines and budget airlines, with prices last updated on March 28, 2025.

This Mytrip deal was found by Cheapflights users on 3/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/245:00 pmMKE - CHS
1 stop15h 36mSpirit Airlines
Thu 5/110:25 amCHS - MKE
1 stop6h 40mSpirit Airlines
Deal found 3/26$155
This Cheapflightsfares deal was found by Cheapflights users on 3/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/1512:22 pmMKE - MYR
1 stop6h 03mSpirit Airlines
Wed 5/216:00 amMYR - MKE
1 stop6h 27mSpirit Airlines
Deal found 3/27$181
This American Airlines deal was found by Cheapflights users on 3/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 4/156:08 amMKE - AGS
1 stop8h 32mAmerican Airlines
Sat 4/194:10 pmAGS - MKE
1 stop7h 48mAmerican Airlines
Deal found 3/27$217
This Mytrip deal was found by Cheapflights users on 3/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 4/285:06 pmMKE - MYR
1 stop18h 58mMultiple Airlines
Thu 5/16:15 amMYR - MKE
1 stop8h 38mMultiple Airlines
Deal found 3/27$225
This Delta deal was found by Cheapflights users on 3/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/217:05 amMKE - CAE
1 stop4h 53mDelta
Sun 5/255:46 pmCAE - MKE
1 stop3h 49mDelta
Deal found 3/27$233
This Frontier deal was found by Cheapflights users on 3/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 4/86:37 pmMKE - CLT
1 stop11h 36mFrontier
Thu 4/1011:20 amCLT - MKE
1 stop8h 43mFrontier
Deal found 3/28$238
This Mytrip deal was found by Cheapflights users on 3/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/102:20 pmMKE - CLT
1 stop18h 16mMultiple Airlines
Wed 4/305:43 pmCLT - MKE
1 stop23h 22mMultiple Airlines
Deal found 3/27$241
This Cheapflightsfares deal was found by Cheapflights users on 3/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/245:00 pmMKE - CLT
1 stop6h 27mSpirit Airlines
Mon 4/2810:57 amCLT - MKE
1 stop5h 49mSpirit Airlines
Deal found 3/27$243
This American Airlines deal was found by Cheapflights users on 3/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/2112:16 pmMKE - CAE
1 stop4h 16mAmerican Airlines
Sun 5/255:10 amCAE - MKE
2 stops7h 05mAmerican Airlines
Deal found 3/27$248
This Delta deal was found by Cheapflights users on 3/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 4/2912:30 pmMKE - AGS
1 stop6h 58mDelta
Fri 5/27:25 pmAGS - MKE
1 stop5h 29mDelta
Deal found 3/27$257
This Delta deal was found by Cheapflights users on 3/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 6/64:56 pmMKE - GSP
1 stop3h 47mDelta
Mon 6/97:57 pmGSP - MKE
1 stop5h 01mDelta
Deal found 3/27$267
This Mytrip deal was found by Cheapflights users on 3/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/12:45 pmMKE - SAV
2 stops31h 28mMultiple Airlines
Mon 5/512:34 pmSAV - MKE
1 stop24h 03mMultiple Airlines
Deal found 3/26$272

Cheapflights Fare Finder

Customize your flight search to find flights from Milwaukee to South Carolina that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated March 28, 2025.
Use the filters below to find and compare flights from Milwaukee to South Carolina that are best for you.

Fly from

Milwaukee

Fly to

South Carolina

Route

Depart

Return

Price

MilwaukeeCharleston

MKE - CHS

MKECHS

Milwaukee-Mitchell

Thu 4/24

5:00 pm-9:36 am

1 stop15h 36m

Charleston

Thu 5/1

10:25 am-4:05 pm

1 stop6h 40m

$155

MilwaukeeMyrtle Beach

MKE - MYR

MKEMYR

Milwaukee-Mitchell

Thu 5/15

12:22 pm-7:25 pm

1 stop6h 03m

Myrtle Beach Intl

Wed 5/21

6:00 am-11:27 am

1 stop6h 27m

$181

MilwaukeeAugusta

MKE - AGS

MKEAGS

Milwaukee-Mitchell

Tue 4/15

6:08 am-3:40 pm

1 stop8h 32m

Augusta Bush Field

Sat 4/19

4:10 pm-10:58 pm

1 stop7h 48m

$217

MilwaukeeMyrtle Beach

MKE - MYR

MKEMYR

Milwaukee-Mitchell

Mon 4/28

5:06 pm-1:04 pm

1 stop18h 58m

Myrtle Beach Intl

Thu 5/1

6:15 am-1:53 pm

1 stop8h 38m

$225

MilwaukeeColumbia

MKE - CAE

MKECAE

Milwaukee-Mitchell

Wed 5/21

7:05 am-12:58 pm

1 stop4h 53m

Columbia Metropolitan

Sun 5/25

5:46 pm-8:35 pm

1 stop3h 49m

$233

MilwaukeeCharlotte

MKE - CLT

MKECLT

Milwaukee-Mitchell

Tue 4/8

6:37 pm-7:13 am

1 stop11h 36m

Charlotte Douglas

Thu 4/10

11:20 am-7:03 pm

1 stop8h 43m

$238

MilwaukeeCharlotte

MKE - CLT

MKECLT

Milwaukee-Mitchell

Thu 4/10

2:20 pm-9:36 am

1 stop18h 16m

Charlotte Douglas

Wed 4/30

5:43 pm-4:05 pm

1 stop23h 22m

$241

MilwaukeeCharlotte

MKE - CLT

MKECLT

Milwaukee-Mitchell

Thu 4/24

5:00 pm-12:27 am

1 stop6h 27m

Charlotte Douglas

Mon 4/28

10:57 am-3:46 pm

1 stop5h 49m

$243

MilwaukeeColumbia

MKE - CAE

MKECAE

Milwaukee-Mitchell

Wed 5/21

12:16 pm-5:32 pm

1 stop4h 16m

Columbia Metropolitan

Sun 5/25

5:10 am-11:15 am

2 stops7h 05m

$248

MilwaukeeAugusta

MKE - AGS

MKEAGS

Milwaukee-Mitchell

Tue 4/29

12:30 pm-8:28 pm

1 stop6h 58m

Augusta Bush Field

Fri 5/2

7:25 pm-11:54 pm

1 stop5h 29m

$257

Flights are sorted by cheapest round-trip flights first.

Deals found on 3/27

Showing 1-10 of 49 results
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Best time to book a flight from Milwaukee to South Carolina

Have a flexible travel schedule? Discover the best time to fly to South Carolina from Milwaukee with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Milwaukee to South Carolina

What is the cheapest month to book a flight from Milwaukee to South Carolina?

Currently, August is the cheapest month in which you can book a flight from Milwaukee to South Carolina (average of $217). Flying from Milwaukee to South Carolina in March is currently the most expensive (average of $335). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from MKE to SC?

Find hourly flight availability from Milwaukee to South Carolina. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated March 28, 2025.

When flying from Milwaukee to South Carolina, the time of day you decide to fly out makes little to no difference towards the overall price you’ll pay on tickets.

Rainfall in South Carolina by month

Plan your trip to South Carolina by taking into account the average rainfall totals by month.

In terms of precipitation, rainfall in South Carolina ranges from 3.0 - 6.5 inches per month. July is typically the wettest month, when rainfall can reach 6.5 in. November is typically the driest time to visit South Carolina when rainfall is around 3.0 in.

Temperature in South Carolina by month

Plan your trip to South Carolina by taking into account the average temperature totals by month.

If weather is an important factor for your trip to South Carolina, use this chart to help with planning. For those seeking warmer temperatures, July is the ideal time of year to visit, when temperatures reach an average of 78.8 F. Travelers looking to avoid the cold should look outside of January, when temperatures are typically at their lowest (around 44.6 F).

Reviews of airlines servicing South Carolina

Get insights into the airlines that provide service to South Carolina. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to South Carolina. Reviews last updated March 28, 2025.
To help decide which airline to fly from Milwaukee to South Carolina, see what other customers have to say about Southwest, Delta and United Airlines. Users can see the overall rating for each airline as well as how each is rated in terms of entertainment options, comfort, food, crew/service, and boarding process.
Southwest
8.1
Very good
4,273 reviews

Crew

8.6

Boarding

8.2

Overall

8.1

Food

7.1

Comfort

8.1

Entertainment

7.6

Reviews

1 / 20
8.0
Excellent

Ila,Mar 2025

HOU - DAL

Our original flight was delayed. We were able to change our flight and got home at close to the same time. Looking forward to when you have assigned seating.
Southwest
8.1
Very good
4,273 reviews
Southwest
8.1
Very good
4,273 reviews

Crew

8.6

Boarding

8.2

Overall

8.1

Food

7.1

Comfort

8.1

Entertainment

7.6

Reviews

1 / 20
8.0
Excellent

Ila,Mar 2025

HOU - DAL

Our original flight was delayed. We were able to change our flight and got home at close to the same time. Looking forward to when you have assigned seating.
Delta
8.0
Very good
7,896 reviews
Southwest
8.1
Very good
4,273 reviews

Crew

8.6

Boarding

8.2

Overall

8.1

Food

7.1

Comfort

8.1

Entertainment

7.6

Reviews

1 / 20
8.0
Excellent

Ila,Mar 2025

HOU - DAL

Our original flight was delayed. We were able to change our flight and got home at close to the same time. Looking forward to when you have assigned seating.
United Airlines
7.4
Good
8,603 reviews
Southwest
8.1
Very good
4,273 reviews

Crew

8.6

Boarding

8.2

Overall

8.1

Food

7.1

Comfort

8.1

Entertainment

7.6

Reviews

1 / 20
8.0
Excellent

Ila,Mar 2025

HOU - DAL

Our original flight was delayed. We were able to change our flight and got home at close to the same time. Looking forward to when you have assigned seating.
American Airlines
7.2
Good
10,000 reviews
Southwest
8.1
Very good
4,273 reviews

Crew

8.6

Boarding

8.2

Overall

8.1

Food

7.1

Comfort

8.1

Entertainment

7.6

Reviews

1 / 20
8.0
Excellent

Ila,Mar 2025

HOU - DAL

Our original flight was delayed. We were able to change our flight and got home at close to the same time. Looking forward to when you have assigned seating.
Spirit Airlines
6.3
Okay
7,881 reviews
Southwest
8.1
Very good
4,273 reviews

Crew

8.6

Boarding

8.2

Overall

8.1

Food

7.1

Comfort

8.1

Entertainment

7.6

Reviews

1 / 20
8.0
Excellent

Ila,Mar 2025

HOU - DAL

Our original flight was delayed. We were able to change our flight and got home at close to the same time. Looking forward to when you have assigned seating.

Related info for your journey

Find useful and relevant information for your journey from Milwaukee to South Carolina. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly from for flights from Milwaukee to South Carolina?

    Milwaukee-Mitchell (MKE), located 6.4 mi from the city center, is the airport you fly out of when you book flights from Milwaukee to South Carolina.

  • What are the cheapest airlines to fly from Milwaukee to South Carolina one-way?

    For one-way options, check prices for Spirit Airlines. According to our data, you can fly for as low as $79. Users have also found prices from $128 and $149 on American Airlines and Delta, respectively.

  • What are the most popular routes from Milwaukee to South Carolina?

    While some choose either Milwaukee-Mitchell - Charleston or Milwaukee-Mitchell - Savannah/Hilton Head, Milwaukee-Mitchell - Charlotte Douglas is the most popular route from Milwaukee to South Carolina.

  • Can I find deals for flights from Milwaukee to South Carolina that include hotel bookings?

    Yes. In addition to deals on Milwaukee to South Carolina flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Milwaukee to South Carolina?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Milwaukee to South Carolina.

  • Can I find deals for business class flights from Milwaukee to South Carolina?

    Yes. Cheapflights offers flight deals from Milwaukee to South Carolina by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Milwaukee to South Carolina?

    Currently, August is the cheapest month in which you can book a flight from Milwaukee to South Carolina (average of $217). Flying from Milwaukee to South Carolina in March is currently the most expensive (average of $335). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

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Alternative routes for Milwaukee to South Carolina

See prices for flight routes from nearby airports that may be better suited for you.
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Top 5 airlines flying from Milwaukee to South Carolina

Discover the top 5 airlines that operate flights from Milwaukee to South Carolina. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated March 28, 2025.
AirlineCheapestAverageFlexibilityOn-time
Spirit AirlinesCheapest$144Average$274FlexibilityNo cancel feeOn-time65%
United AirlinesCheapest$213Average$386FlexibilityNo cancel feeOn-time69%
DeltaCheapest$216Average$383FlexibilityNo cancel feeOn-timeN/A
American AirlinesCheapest$216Average$371FlexibilityNo cancel feeOn-time71%
SouthwestCheapest$256Average$395FlexibilityNo cancel feeOn-time63%
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