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$126+ Cheap flights from Milwaukee (MKE) to South Carolina

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 3/28. Fares are subject to change and may not be available on all flights or dates of travel.
MKE — CHS
Jan 25 — Feb 11
Sat 1/25
Sat 2/1
1 adult, Economy
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Cheap flight deals from Milwaukee to South Carolina

Discover tips and strategies to find the most affordable flight options for your journey from Milwaukee (MKE) to South Carolina (USSC). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated January 20, 2025.

Round-trip from

$159
(American Airlines)

One-way from

$126
(Mytrip)
From Milwaukee-Mitchell to South Carolina
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One-way flight from Milwaukee-Mitchell to South Carolina
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Find flight deals from Milwaukee to South Carolina

Cheapest flights from Milwaukee to South Carolina
Explore the most affordable flight options available from Milwaukee to South Carolina. Find the lowest fares from popular airlines and budget airlines, with prices last updated on January 20, 2025.

This American Airlines deal was found by Cheapflights users on 1/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 2/186:19 pmMKE - AGS
1 stop4h 27mAmerican Airlines
Tue 2/257:45 amAGS - MKE
1 stop4h 41mAmerican Airlines
Deal found 1/19$159
This CheapOair deal was found by Cheapflights users on 1/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 2/35:28 pmMKE - MYR
1 stop19h 47mSpirit Airlines
Fri 2/79:11 amMYR - MKE
1 stop8h 12mSpirit Airlines
Deal found 1/19$171
This CheapOair deal was found by Cheapflights users on 1/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 2/236:47 pmMKE - CLT
1 stop24h 00mSpirit Airlines
Wed 2/264:18 pmCLT - MKE
1 stop26h 34mSpirit Airlines
Deal found 1/20$200
This Justfly.com deal was found by Cheapflights users on 1/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Justfly.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 4/510:14 amMKE - CLT
1 stop5h 48mMultiple Airlines
Sat 4/127:54 pmCLT - MKE
1 stop14h 33mMultiple Airlines
Deal found 1/20$212
This CheapOair deal was found by Cheapflights users on 1/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/1410:30 amMKE - CHS
1 stop28h 29mSpirit Airlines
Mon 5/194:49 pmCHS - MKE
1 stop17h 41mSpirit Airlines
Deal found 1/19$222
This Mytrip deal was found by Cheapflights users on 1/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 3/32:14 pmMKE - CLT
1 stop15h 54mFrontier
Fri 3/77:38 pmCLT - MKE
1 stop17h 41mFrontier
Deal found 1/20$249
This Delta deal was found by Cheapflights users on 1/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 2/202:20 pmMKE - CAE
1 stop7h 23mDelta
Mon 2/245:35 amCAE - MKE
1 stop4h 46mDelta
Deal found 1/20$249
This Delta deal was found by Cheapflights users on 1/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 2/35:44 amMKE - AGS
1 stop4h 38mDelta
Fri 2/77:21 pmAGS - MKE
1 stop5h 32mDelta
Deal found 1/19$277
This Mytrip deal was found by Cheapflights users on 1/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 2/286:47 pmMKE - CHS
2 stops20h 36mMultiple Airlines
Fri 3/710:48 amCHS - MKE
1 stop6h 57mMultiple Airlines
Deal found 1/18$286
This Delta deal was found by Cheapflights users on 1/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 2/126:50 amMKE - MYR
1 stop4h 21mDelta
Sat 2/2212:56 pmMYR - MKE
1 stop4h 23mDelta
Deal found 1/20$297
This American Airlines deal was found by Cheapflights users on 1/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 3/511:29 amMKE - SAV
1 stop5h 15mAmerican Airlines
Tue 3/115:37 pmSAV - MKE
1 stop6h 06mAmerican Airlines
Deal found 1/19$297
This Delta deal was found by Cheapflights users on 1/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 2/41:10 pmMKE - CHS
1 stop6h 21mDelta
Sat 2/810:01 amCHS - MKE
1 stop6h 39mDelta
Deal found 1/20$297

Find flights from Milwaukee to South Carolina within your budget

Customize your flight search to find flights from Milwaukee to South Carolina that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated January 20, 2025.

Fly from

Any airport

Fly to

Any airport

Route

Depart

Return

Price

MilwaukeeAugusta

MKE - AGS

MKEAGS

Milwaukee-Mitchell

Tue 2/18

6:19 pm-11:46 pm

1 stop4h 27m

Augusta Bush Field

Sat 2/22

6:27 pm-10:07 pm

1 stop4h 40m

$159

MilwaukeeMyrtle Beach

MKE - MYR

MKEMYR

Milwaukee-Mitchell

Mon 2/3

5:28 pm-2:15 pm

1 stop19h 47m

Myrtle Beach Intl

Fri 2/7

9:11 am-4:23 pm

1 stop8h 12m

$171

MilwaukeeColumbia

MKE - CAE

MKECAE

Milwaukee-Mitchell

Wed 2/12

6:44 am-12:27 pm

1 stop4h 43m

Columbia Metropolitan

Sat 2/15

6:01 pm-10:07 pm

1 stop5h 06m

$199

MilwaukeeCharlotte

MKE - CLT

MKECLT

Milwaukee-Mitchell

Sun 2/23

6:47 pm-7:47 pm

1 stop24h 00m

Charlotte Douglas

Wed 2/26

4:18 pm-5:52 pm

1 stop26h 34m

$200

MilwaukeeCharlotte

MKE - CLT

MKECLT

Milwaukee-Mitchell

Mon 3/17

5:40 pm-5:44 pm

1 stop23h 04m

Charlotte Douglas

Thu 3/20

7:44 pm-9:14 am

1 stop14h 30m

$206

MilwaukeeCharleston

MKE - CHS

MKECHS

Milwaukee-Mitchell

Wed 5/14

10:30 am-3:59 pm

1 stop28h 29m

Charleston

Mon 5/19

4:49 pm-9:30 am

1 stop17h 41m

$222

MilwaukeeColumbia

MKE - CAE

MKECAE

Milwaukee-Mitchell

Wed 2/19

5:21 pm-11:39 pm

1 stop5h 18m

Columbia Metropolitan

Sat 2/22

1:00 pm-5:18 pm

1 stop5h 18m

$237

MilwaukeeCharlotte

MKE - CLT

MKECLT

Milwaukee-Mitchell

Thu 3/13

10:32 am-10:03 pm

1 stop10h 31m

Charlotte Douglas

Mon 3/17

7:38 pm-12:19 pm

1 stop17h 41m

$240

MilwaukeeAugusta

MKE - AGS

MKEAGS

Milwaukee-Mitchell

Mon 2/3

5:44 am-11:22 am

1 stop4h 38m

Augusta Bush Field

Fri 2/7

7:21 pm-11:53 pm

1 stop5h 32m

$277

MilwaukeeCharleston

MKE - CHS

MKECHS

Milwaukee-Mitchell

Fri 2/28

6:47 pm-4:23 pm

2 stops20h 36m

Charleston

Fri 3/7

10:48 am-4:45 pm

1 stop6h 57m

$286

Flights are sorted by cheapest round-trip flights first.

Deals found on 1/20

Showing 1-10 of 56 results
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Best time to book a flight from Milwaukee to South Carolina

Have a flexible travel schedule? Discover the best time to fly to South Carolina from Milwaukee with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Travel insights for flights from Milwaukee to South Carolina

Get recent, data-driven insights about flights from Milwaukee to South Carolina including ideal travel times, pricing trends, and more.

What is the cheapest month to book a flight from Milwaukee to South Carolina?

Currently, August is the cheapest month in which you can book a flight from Milwaukee to South Carolina (average of $217). Flying from Milwaukee to South Carolina in March is currently the most expensive (average of $335). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from MKE to SC?

Find hourly flight availability from Milwaukee to South Carolina. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated January 20, 2025.

When flying from Milwaukee to South Carolina, the time of day you decide to fly out makes little to no difference towards the overall price you’ll pay on tickets.

Rainfall in South Carolina by month

Plan your trip to South Carolina by taking into account the average rainfall totals by month.

In terms of precipitation, rainfall in South Carolina ranges from 3.0 - 6.5 inches per month. July is typically the wettest month, when rainfall can reach 6.5 in. November is typically the driest time to visit South Carolina when rainfall is around 3.0 in.

Temperature in South Carolina by month

Plan your trip to South Carolina by taking into account the average temperature totals by month.

If weather is an important factor for your trip to South Carolina, use this chart to help with planning. For those seeking warmer temperatures, July is the ideal time of year to visit, when temperatures reach an average of 78.8 F. Travelers looking to avoid the cold should look outside of January, when temperatures are typically at their lowest (around 44.6 F).

Reviews of airlines servicing South Carolina

Get insights into the airlines that provide service to South Carolina. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to South Carolina. Reviews last updated January 20, 2025.
To help decide which airline to fly from Milwaukee to South Carolina, see what other customers have to say about Spirit Airlines, Southwest and American Airlines. Users can see the overall rating for each airline as well as how each is rated in terms of entertainment options, comfort, food, crew/service, and boarding process.
Southwest
8.1
Very good
4,659 reviews

Overall

8.1

Food

7.2

Crew

8.7

Comfort

8.1

Entertainment

7.7

Boarding

8.2

Reviews

1 / 10

We BARELY made the connection and when we got onboard we were treated like disobedient children who should have arrived earlier because we had to ask other passengers to move so we could sit with our kids. The flight attendants on the first flight were nice but the second one, they were snippy and fairly rude.

Southwest
8.1
Very good
4,659 reviews
Southwest
8.1
Very good
4,659 reviews

Overall

8.1

Food

7.2

Crew

8.7

Comfort

8.1

Entertainment

7.7

Boarding

8.2

Reviews

1 / 10

We BARELY made the connection and when we got onboard we were treated like disobedient children who should have arrived earlier because we had to ask other passengers to move so we could sit with our kids. The flight attendants on the first flight were nice but the second one, they were snippy and fairly rude.

Delta
8.0
Very good
8,521 reviews
Southwest
8.1
Very good
4,659 reviews

Overall

8.1

Food

7.2

Crew

8.7

Comfort

8.1

Entertainment

7.7

Boarding

8.2

Reviews

1 / 10

We BARELY made the connection and when we got onboard we were treated like disobedient children who should have arrived earlier because we had to ask other passengers to move so we could sit with our kids. The flight attendants on the first flight were nice but the second one, they were snippy and fairly rude.

United Airlines
7.4
Good
8,982 reviews
Southwest
8.1
Very good
4,659 reviews

Overall

8.1

Food

7.2

Crew

8.7

Comfort

8.1

Entertainment

7.7

Boarding

8.2

Reviews

1 / 10

We BARELY made the connection and when we got onboard we were treated like disobedient children who should have arrived earlier because we had to ask other passengers to move so we could sit with our kids. The flight attendants on the first flight were nice but the second one, they were snippy and fairly rude.

American Airlines
7.2
Good
10,000 reviews
Southwest
8.1
Very good
4,659 reviews

Overall

8.1

Food

7.2

Crew

8.7

Comfort

8.1

Entertainment

7.7

Boarding

8.2

Reviews

1 / 10

We BARELY made the connection and when we got onboard we were treated like disobedient children who should have arrived earlier because we had to ask other passengers to move so we could sit with our kids. The flight attendants on the first flight were nice but the second one, they were snippy and fairly rude.

Spirit Airlines
6.3
Okay
8,113 reviews
Southwest
8.1
Very good
4,659 reviews

Overall

8.1

Food

7.2

Crew

8.7

Comfort

8.1

Entertainment

7.7

Boarding

8.2

Reviews

1 / 10

We BARELY made the connection and when we got onboard we were treated like disobedient children who should have arrived earlier because we had to ask other passengers to move so we could sit with our kids. The flight attendants on the first flight were nice but the second one, they were snippy and fairly rude.

Related info for your journey

Find useful and relevant information for your journey from Milwaukee to South Carolina. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly from for flights from Milwaukee to South Carolina?

    Milwaukee-Mitchell (MKE), located 6.4 mi from the city center, is the airport you fly out of when you book flights from Milwaukee to South Carolina.

  • What are the cheapest airlines to fly from Milwaukee to South Carolina one-way?

    For one-way options, check prices for Spirit Airlines. According to our data, you can fly for as low as $126. Users have also found prices from $149 and $149 on Delta and American Airlines, respectively.

  • What are the most popular routes from Milwaukee to South Carolina?

    While some choose either Milwaukee-Mitchell - Charleston or Milwaukee-Mitchell - Savannah/Hilton Head, Milwaukee-Mitchell - Charlotte Douglas is the most popular route from Milwaukee to South Carolina.

  • Can I find deals for flights from Milwaukee to South Carolina that include hotel bookings?

    Yes. In addition to deals on Milwaukee to South Carolina flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Milwaukee to South Carolina?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Milwaukee to South Carolina.

  • Can I find deals for business class flights from Milwaukee to South Carolina?

    Yes. Cheapflights offers flight deals from Milwaukee to South Carolina by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Milwaukee to South Carolina?

    Currently, August is the cheapest month in which you can book a flight from Milwaukee to South Carolina (average of $217). Flying from Milwaukee to South Carolina in March is currently the most expensive (average of $335). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

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Alternative routes for Milwaukee to South Carolina

See prices for flight routes from nearby airports that may be better suited for you.
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Top 5 airlines flying from Milwaukee to South Carolina

Discover the top 5 airlines that operate flights from Milwaukee to South Carolina. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated January 20, 2025.
AirlineCheapestAverageFlexibilityOn-time
Spirit AirlinesCheapest$155Average$268FlexibilityNo cancel feeOn-time65%
American AirlinesCheapest$213Average$365FlexibilityNo cancel feeOn-time71%
United AirlinesCheapest$216Average$394FlexibilityNo cancel feeOn-time69%
DeltaCheapest$216Average$378FlexibilityNo cancel feeOn-timeN/A
SouthwestCheapest$296Average$386FlexibilityNo cancel feeOn-time63%
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