South Carolina

$212+ Cheap flights from Mexico City Federal District to South Carolina

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 5/15. Fares are subject to change and may not be available on all flights or dates of travel.
MEX — CHS
Apr 22 — Apr 291
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Cheap flight deals from Mexico City Federal District to South Carolina

Keep the following information in mind while searching for Mexico City Federal District to South Carolina flight deals. Data was last updated April 17, 2025.

Most accurate provider

AranGrant
3 stars

Most trusted provider

AranGrant
3 stars

Round-trip from

$422
(Mytrip)

One-way from

$212
(OneTravel)

Popular in

July

Cheapest in

April

Average price

$516
Provider with most accurate pricing for Mexico City Benito Juarez-Myrtle Beach Intl flight deals.
Provider most trusted by Cheapflights users for Mexico City Benito Juarez-Myrtle Beach Intl flights.
From Mexico City Federal District to South Carolina
One-way flight from Mexico City Federal District to South Carolina
Highest demand for flights based on searches. 17% potential increase in price ($141 potential increase over avg. RT price).
Cheapest flight prices on average. 5% potential price decrease ($33 potential savings vs. average RT price).
Average for round-trip flights in April 2025

Find flight deals from Mexico City Federal District to South Carolina

Cheapest flights from Mexico City Federal District to South Carolina
Explore the most affordable flight options available from Mexico City Federal District to South Carolina. Find the lowest fares from popular airlines and budget airlines, with prices last updated on April 17, 2025.

This Mytrip deal was found by Cheapflights users on 4/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/96:20 amMEX - CHS
2 stops24h 18mMultiple Airlines
Fri 5/1612:33 pmCHS - MEX
3 stops35h 27mMultiple Airlines
Deal found 4/17$422
This Delta deal was found by Cheapflights users on 4/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 4/288:45 amMEX - GSP
2 stops11h 00mDelta
Tue 5/65:46 amGSP - MEX
2 stops11h 09mDelta
Deal found 4/17$441
This Delta deal was found by Cheapflights users on 4/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/243:30 pmMEX - CHS
1 stop6h 28mDelta
Tue 5/2012:22 pmCHS - MEX
1 stop8h 18mDelta
Deal found 4/16$441
This Aeromexico deal was found by Cheapflights users on 4/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Aeromexico is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 4/296:01 amMEX - GSP
2 stops14h 22mAeromexico
Tue 5/610:11 amGSP - MEX
1 stop5h 44mAeromexico
Deal found 4/17$442
This CheapOair deal was found by Cheapflights users on 4/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 6/199:55 amMEX - CLT
1 stop26h 39mFrontier
Mon 6/239:17 pmCLT - MEX
1 stop24h 18mFrontier
Deal found 4/17$455
This Mytrip deal was found by Cheapflights users on 4/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/65:30 amMEX - CLT
3 stops16h 57mMultiple Airlines
Wed 5/215:45 amCLT - MEX
3 stops18h 55mMultiple Airlines
Deal found 4/17$457
This United Airlines deal was found by Cheapflights users on 4/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/304:40 amMEX - CHS
1 stop15h 13mUnited Airlines
Sat 5/32:40 pmCHS - MEX
1 stop8h 30mUnited Airlines
Deal found 4/16$461
This American Airlines deal was found by Cheapflights users on 4/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/305:00 amMEX - CHS
2 stops11h 09mAmerican Airlines
Sat 5/35:10 amCHS - MEX
2 stops9h 00mAmerican Airlines
Deal found 4/16$474
This Delta deal was found by Cheapflights users on 4/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 4/299:01 amMEX - CLT
2 stops10h 10mDelta
Fri 5/92:21 pmCLT - MEX
2 stops8h 44mDelta
Deal found 4/17$476
This United Airlines deal was found by Cheapflights users on 4/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 5/118:45 amMEX - CLT
1 stop27h 26mUnited Airlines
Sun 5/186:30 amCLT - MEX
1 stop28h 05mUnited Airlines
Deal found 4/17$477
This American Airlines deal was found by Cheapflights users on 4/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 4/261:55 pmMEX - CLT
1 stop16h 12mAmerican Airlines
Wed 4/309:20 amCLT - MEX
Nonstop4h 15mAmerican Airlines
Deal found 4/17$483
This eDestinos deal was found by Cheapflights users on 4/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure eDestinos is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/317:05 amMEX - CAE
1 stop7h 54mAeromexico
Sat 6/711:47 amCAE - MEX
2 stops11h 08mAeromexico
Deal found 4/16$489

Cheapflights Fare Finder

Customize your flight search to find flights from Mexico City Federal District to South Carolina that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated April 17, 2025.
Use the filters below to find and compare flights from Mexico City Federal District to South Carolina that are best for you.

Fly from

Mexico City Federal District

Fly to

South Carolina

Route

Depart

Return

Price

Mexico CityCharleston

MEX - CHS

MEXCHS

Mexico City Benito Juarez

Fri 5/9

6:20 am-8:38 am

2 stops24h 18m

Charleston

Fri 5/16

12:33 pm-10:00 pm

3 stops35h 27m

$422

Mexico CityGreenville

MEX - GSP

MEXGSP

Mexico City Benito Juarez

Mon 4/28

8:45 am-11:53 pm

2 stops13h 08m

Greenville

Tue 5/6

11:45 am-6:40 pm

1 stop8h 55m

$441

Mexico CityGreenville

MEX - GSP

MEXGSP

Mexico City Benito Juarez

Tue 4/29

6:01 am-10:23 pm

2 stops14h 22m

Greenville

Tue 5/6

10:11 am-1:55 pm

1 stop5h 44m

$442

Mexico CityCharlotte

MEX - CLT

MEXCLT

Mexico City Benito Juarez

Thu 6/19

9:55 am-2:34 pm

1 stop26h 39m

Charlotte Douglas

Mon 6/23

9:17 pm-7:35 pm

1 stop24h 18m

$455

Mexico CityCharlotte

MEX - CLT

MEXCLT

Mexico City Benito Juarez

Tue 5/6

5:30 am-12:27 am

3 stops16h 57m

Charlotte Douglas

Wed 5/21

5:45 am-10:40 pm

3 stops18h 55m

$457

Mexico CityCharleston

MEX - CHS

MEXCHS

Mexico City Benito Juarez

Fri 5/16

7:05 am-5:19 pm

1 stop8h 14m

Charleston

Mon 5/19

2:38 pm-8:45 pm

1 stop8h 07m

$459

Mexico CityGreenville

MEX - GSP

MEXGSP

Mexico City Benito Juarez

Sun 4/27

6:30 am-11:29 pm

1 stop14h 59m

Greenville

Tue 5/6

6:45 am-12:45 pm

1 stop8h 00m

$460

Mexico CityCharleston

MEX - CHS

MEXCHS

Mexico City Benito Juarez

Wed 4/30

4:40 am-9:53 pm

1 stop15h 13m

Charleston

Sat 5/3

2:40 pm-9:10 pm

1 stop8h 30m

$461

Mexico CityCharleston

MEX - CHS

MEXCHS

Mexico City Benito Juarez

Wed 4/30

5:00 am-6:09 pm

2 stops11h 09m

Charleston

Sat 5/3

5:10 am-12:10 pm

2 stops9h 00m

$474

Mexico CityCharlotte

MEX - CLT

MEXCLT

Mexico City Benito Juarez

Tue 4/29

7:05 am-4:26 pm

1 stop7h 21m

Charlotte Douglas

Fri 5/9

7:00 am-2:25 pm

1 stop9h 25m

$476

Flights are sorted by cheapest round-trip flights first.

Deals found on 4/17

Showing 1-10 of 43 results
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Best time to book a flight from Mexico City Federal District to South Carolina

Have a flexible travel schedule? Discover the best time to fly to South Carolina from Mexico City Federal District with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Mexico City Federal District to South Carolina

What is the cheapest month to book a flight from Mexico City Federal District to South Carolina?

Currently, August is the cheapest month in which you can book a flight from Mexico City Federal District to South Carolina (average of $217). Flying from Mexico City Federal District to South Carolina in March is currently the most expensive (average of $335). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from DF to SC?

Find hourly flight availability from Mexico City Federal District to South Carolina. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated April 17, 2025.

When flying from Mexico City Federal District to South Carolina, the time of day you decide to fly out makes little to no difference towards the overall price you’ll pay on tickets.

Rainfall in South Carolina by month

Plan your trip to South Carolina by taking into account the average rainfall totals by month.

In terms of precipitation, rainfall in South Carolina ranges from 3.0 - 6.5 inches per month. July is typically the wettest month, when rainfall can reach 6.5 in. November is typically the driest time to visit South Carolina when rainfall is around 3.0 in.

Temperature in South Carolina by month

Plan your trip to South Carolina by taking into account the average temperature totals by month.

If weather is an important factor for your trip to South Carolina, use this chart to help with planning. For those seeking warmer temperatures, July is the ideal time of year to visit, when temperatures reach an average of 78.8 F. Travelers looking to avoid the cold should look outside of January, when temperatures are typically at their lowest (around 44.6 F).

Reviews of airlines servicing South Carolina

Get insights into the airlines that provide service to South Carolina. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to South Carolina. Reviews last updated April 17, 2025.
To help decide which airline to fly from Mexico City Federal District to South Carolina, see what other customers have to say about Delta, Aeromexico and United Airlines. Users can see the overall rating for each airline as well as how each is rated in terms of entertainment options, comfort, food, crew/service, and boarding process.
8.0
Very good

Overall

8.0

Comfort

7.9

Entertainment

7.9

Crew

8.5

Food

7.3

Boarding

8.2

Reviews

1 / 20
10.0
Excellent

Aaron,Oct 2024

TUS - LAX

Delta has consistently been the best U.S. airline for my travels and this flight was no exception
8.0
Very good
8.0
Very good

Overall

8.0

Comfort

7.9

Entertainment

7.9

Crew

8.5

Food

7.3

Boarding

8.2

Reviews

1 / 20
10.0
Excellent

Aaron,Oct 2024

TUS - LAX

Delta has consistently been the best U.S. airline for my travels and this flight was no exception
8.0
Very good

Overall

8.0

Comfort

7.9

Entertainment

7.9

Crew

8.5

Food

7.3

Boarding

8.2

Reviews

1 / 20
10.0
Excellent

Aaron,Oct 2024

TUS - LAX

Delta has consistently been the best U.S. airline for my travels and this flight was no exception
8.0
Very good

Overall

8.0

Comfort

7.9

Entertainment

7.9

Crew

8.5

Food

7.3

Boarding

8.2

Reviews

1 / 20
10.0
Excellent

Aaron,Oct 2024

TUS - LAX

Delta has consistently been the best U.S. airline for my travels and this flight was no exception
8.0
Very good

Overall

8.0

Comfort

7.9

Entertainment

7.9

Crew

8.5

Food

7.3

Boarding

8.2

Reviews

1 / 20
10.0
Excellent

Aaron,Oct 2024

TUS - LAX

Delta has consistently been the best U.S. airline for my travels and this flight was no exception
8.0
Very good

Overall

8.0

Comfort

7.9

Entertainment

7.9

Crew

8.5

Food

7.3

Boarding

8.2

Reviews

1 / 20
10.0
Excellent

Aaron,Oct 2024

TUS - LAX

Delta has consistently been the best U.S. airline for my travels and this flight was no exception

Related info for your journey

Find useful and relevant information for your journey from Mexico City Federal District to South Carolina. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
  • What are the cheapest airlines to fly from Mexico City Federal District to South Carolina one-way?

    For one-way options, check prices for Volaris. According to our data, you can fly for as low as $212. Users have also found prices from $281 and $299 on Frontier and Delta, respectively.

  • Can I find deals for flights from Mexico City Federal District to South Carolina that include hotel bookings?

    Yes. In addition to deals on Mexico City Federal District to South Carolina flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Mexico City Federal District to South Carolina?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Mexico City Federal District to South Carolina.

  • Can I find deals for business class flights from Mexico City Federal District to South Carolina?

    Yes. Cheapflights offers flight deals from Mexico City Federal District to South Carolina by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Mexico City Federal District to South Carolina?

    Currently, August is the cheapest month in which you can book a flight from Mexico City Federal District to South Carolina (average of $217). Flying from Mexico City Federal District to South Carolina in March is currently the most expensive (average of $335). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Browse thousands of different options on Cheapflights for your next trip

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Alternative routes for Mexico City Federal District to South Carolina

See prices for flight routes from nearby airports that may be better suited for you.

Top 3 airlines flying from Mexico City Federal District to South Carolina

Discover the top 3 airlines that operate flights from Mexico City Federal District to South Carolina. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated April 17, 2025.
AirlineCheapestAverageFlexibilityOn-time
DeltaCheapest$441Average$599FlexibilityNo cancel feeOn-timeN/A
United AirlinesCheapest$467Average$516FlexibilityNo cancel feeOn-time69%
American AirlinesCheapest$527Average$583FlexibilityNo cancel feeOn-time71%

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