HomeSearch by dateVacation packagesHotelsFlight dealsCar rentalTravel tips & news
South Carolina

$144+ Cheap flights from Melbourne, FL (MLB) to South Carolina

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 5/14. Fares are subject to change and may not be available on all flights or dates of travel.
MLB — CHS
abr. 22 — abr. 291
mar. 4/22
mar. 4/29
1 adult, Economy
We work with more than 300 partners to bring you better travel deals

Find cheap flights from Melbourne to South Carolina with Cheapflights

1. Tell us where you want to go

Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”

2. Select your favorite providers

We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.

3. Compare prices and book

Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.

Cheap flight deals from Melbourne to South Carolina

Keep the following information in mind while searching for Melbourne to South Carolina flight deals. Data was last updated abril 17, 2025.

Most accurate provider

eDreams
3 stars

Most trusted provider

eDreams
3 stars

Round-trip from

$287
(Delta)

One-way from

$144
(Delta)

Popular in

April

Cheapest in

February

Average price

$194
Provider with most accurate pricing for Orlando (ORL)-Myrtle Beach Intl flight deals.
Search Deals
Provider most trusted by Cheapflights users for Orlando (ORL)-Myrtle Beach Intl flights.
Search Deals
From Melbourne to South Carolina
Search Deals
One-way flight from Melbourne to South Carolina
Search Deals
Highest demand for flights based on searches. 8% potential increase in price ($13 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 2% potential price decrease ($5 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in April 2025
Search Deals

Find flight deals from Melbourne to South Carolina

Cheapest flights from Melbourne to South Carolina
Explore the most affordable flight options available from Melbourne to South Carolina. Find the lowest fares from popular airlines and budget airlines, with prices last updated on abril 17, 2025.

This Delta deal was found by Cheapflights users on 4/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mié. 7/95:55 amMLB - CAE
1 stop6h 37mDelta
sáb. 7/1211:55 amCAE - MLB
1 stop6h 08mDelta
Deal found 4/17$287
This American Airlines deal was found by Cheapflights users on 4/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
lun. 5/195:45 pmMLB - CLT
Nonstop1h 49mAmerican Airlines
mié. 5/2810:30 pmCLT - MLB
Nonstop1h 40mAmerican Airlines
Deal found 4/16$308
This Delta deal was found by Cheapflights users on 4/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mar. 5/136:00 amMLB - MYR
1 stop6h 13mDelta
mié. 5/146:00 amMYR - MLB
1 stop4h 40mDelta
Deal found 4/17$309
This Delta deal was found by Cheapflights users on 4/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mié. 7/235:55 amMLB - CHS
1 stop3h 48mDelta
mar. 7/296:20 amCHS - MLB
1 stop4h 16mDelta
Deal found 4/16$317
This Delta deal was found by Cheapflights users on 4/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
sáb. 5/174:35 pmMLB - GSP
1 stop4h 56mDelta
mié. 5/215:30 amGSP - MLB
1 stop5h 10mDelta
Deal found 4/17$318
This American Airlines deal was found by Cheapflights users on 4/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
sáb. 5/171:47 pmMLB - GSP
2 stops9h 33mAmerican Airlines
mié. 5/218:35 pmGSP - MLB
1 stop3h 35mAmerican Airlines
Deal found 4/17$323
This Delta deal was found by Cheapflights users on 4/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mié. 10/226:35 pmMLB - CLT
1 stop5h 19mDelta
dom. 10/265:30 amCLT - MLB
1 stop5h 04mDelta
Deal found 4/17$328
This American Airlines deal was found by Cheapflights users on 4/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mar. 5/65:45 pmMLB - CHS
1 stop4h 19mAmerican Airlines
sáb. 5/105:07 amCHS - MLB
1 stop6h 23mAmerican Airlines
Deal found 4/15$331
This Mytrip deal was found by Cheapflights users on 4/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
jue. 5/18:44 pmMLB - CHS
1 stop18h 29mMultiple Airlines
dom. 5/43:56 pmCHS - MLB
1 stop23h 08mMultiple Airlines
Deal found 4/17$390
This American Airlines deal was found by Cheapflights users on 4/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
vie. 5/21:50 pmMLB - MYR
1 stop5h 12mAmerican Airlines
mar. 5/67:54 pmMYR - MLB
1 stop4h 16mAmerican Airlines
Deal found 4/17$407
This Delta deal was found by Cheapflights users on 4/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
jue. 5/16:42 pmMLB - SAV
1 stop5h 15mDelta
dom. 5/45:30 amSAV - MLB
1 stop5h 03mDelta
Deal found 4/17$407
This American Airlines deal was found by Cheapflights users on 4/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
vie. 5/21:50 pmMLB - CAE
1 stop4h 12mAmerican Airlines
mar. 5/67:10 amCAE - MLB
1 stop4h 20mAmerican Airlines
Deal found 4/17$427

Cheapflights Fare Finder

Customize your flight search to find flights from Melbourne to South Carolina that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated abril 17, 2025.
Use the filters below to find and compare flights from Melbourne to South Carolina that are best for you.

Fly from

Melbourne

Fly to

South Carolina

Route

Depart

Return

Price

MelbourneColumbia

MLB - CAE

MLBCAE

Melbourne

mié. 7/9

5:55 am-12:32 pm

1 stop6h 37m

Columbia Metropolitan

sáb. 7/12

11:55 am-6:03 pm

1 stop6h 08m

$287

MelbourneCharlotte

MLB - CLT

MLBCLT

Melbourne

lun. 5/19

5:45 pm-7:34 pm

Nonstop1h 49m

Charlotte Douglas

mié. 5/28

10:30 pm-12:10 am

Nonstop1h 40m

$308

MelbourneMyrtle Beach

MLB - MYR

MLBMYR

Melbourne

mar. 5/13

6:00 am-12:13 pm

1 stop6h 13m

Myrtle Beach Intl

mié. 5/14

6:00 am-10:40 am

1 stop4h 40m

$309

MelbourneGreenville

MLB - GSP

MLBGSP

Melbourne

sáb. 5/17

4:35 pm-9:31 pm

1 stop4h 56m

Greenville

mié. 5/21

5:30 am-10:40 am

1 stop5h 10m

$318

MelbourneGreenville

MLB - GSP

MLBGSP

Melbourne

sáb. 5/17

1:47 pm-11:20 pm

2 stops9h 33m

Greenville

mié. 5/21

8:35 pm-12:10 am

1 stop3h 35m

$323

MelbourneCharlotte

MLB - CLT

MLBCLT

Melbourne

lun. 5/19

11:25 am-2:56 pm

1 stop3h 31m

Charlotte Douglas

mié. 5/28

8:20 am-1:43 pm

1 stop5h 23m

$328

MelbourneCharleston

MLB - CHS

MLBCHS

Melbourne

mar. 5/6

5:45 pm-10:04 pm

1 stop4h 19m

Charleston

sáb. 5/10

5:07 am-11:30 am

1 stop6h 23m

$331

MelbourneCharleston

MLB - CHS

MLBCHS

Melbourne

vie. 6/20

7:06 pm-11:59 pm

1 stop4h 53m

Charleston

lun. 6/23

6:16 pm-11:52 pm

1 stop5h 36m

$357

MelbourneCharleston

MLB - CHS

MLBCHS

Melbourne

jue. 5/1

8:44 pm-3:13 pm

1 stop18h 29m

Charleston

dom. 5/4

3:56 pm-3:04 pm

1 stop23h 08m

$390

MelbourneMyrtle Beach

MLB - MYR

MLBMYR

Melbourne

vie. 5/2

1:50 pm-7:02 pm

1 stop5h 12m

Myrtle Beach Intl

mar. 5/6

7:54 pm-12:10 am

1 stop4h 16m

$407

Flights are sorted by cheapest round-trip flights first.

Deals found on 4/16

Showing 1-10 of 19 results
1
2

Best time to book a flight from Melbourne to South Carolina

Have a flexible travel schedule? Discover the best time to fly to South Carolina from Melbourne with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Melbourne to South Carolina

What is the cheapest month to book a flight from Melbourne, Florida to South Carolina?

Currently, August is the cheapest month in which you can book a flight from Melbourne, Florida to South Carolina (average of $217). Flying from Melbourne, Florida to South Carolina in March is currently the most expensive (average of $335). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from MLB to SC?

Find hourly flight availability from Melbourne to South Carolina. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated abril 17, 2025.

Regardless of the time of day you decide to fly, the ticket price will remain around the same. Book flights from Melbourne, Florida to South Carolina as you normally would.

Rainfall in South Carolina by month

Plan your trip to South Carolina by taking into account the average rainfall totals by month.

In terms of precipitation, rainfall in South Carolina ranges from 3.0 - 6.5 inches per month. July is typically the wettest month, when rainfall can reach 6.5 in. November is typically the driest time to visit South Carolina when rainfall is around 3.0 in.

Temperature in South Carolina by month

Plan your trip to South Carolina by taking into account the average temperature totals by month.

If weather is an important factor for your trip to South Carolina, use this chart to help with planning. For those seeking warmer temperatures, July is the ideal time of year to visit, when temperatures reach an average of 78.8 F. Travelers looking to avoid the cold should look outside of January, when temperatures are typically at their lowest (around 44.6 F).

Reviews of airlines servicing South Carolina

Get insights into the airlines that provide service to South Carolina. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to South Carolina. Reviews last updated abril 17, 2025.
See what other customers who have flown with Delta and American Airlines from Melbourne to South Carolina have to say. Reviews also offer insight into each airline's entertainment options, comfort, food, crew/service, and boarding process.
Delta
8.0
Very good
7,916 reviews

Boarding

8.2

Comfort

7.9

Overall

8.0

Food

7.3

Crew

8.5

Entertainment

7.9

Reviews

1 / 20
10.0
Excellent

Kymberlee,Oct 2024

JFK - ATL

Overall it was good on the flight. Before the flight with checking the bag at JFK was a nightmare. It took way too long and the Delta concierge was very rude to everyone. But other than that it was fine.
Delta
8.0
Very good
7,916 reviews
Delta
8.0
Very good
7,916 reviews

Boarding

8.2

Comfort

7.9

Overall

8.0

Food

7.3

Crew

8.5

Entertainment

7.9

Reviews

1 / 20
10.0
Excellent

Kymberlee,Oct 2024

JFK - ATL

Overall it was good on the flight. Before the flight with checking the bag at JFK was a nightmare. It took way too long and the Delta concierge was very rude to everyone. But other than that it was fine.
American Airlines
7.2
Good
10,000 reviews
Delta
8.0
Very good
7,916 reviews

Boarding

8.2

Comfort

7.9

Overall

8.0

Food

7.3

Crew

8.5

Entertainment

7.9

Reviews

1 / 20
10.0
Excellent

Kymberlee,Oct 2024

JFK - ATL

Overall it was good on the flight. Before the flight with checking the bag at JFK was a nightmare. It took way too long and the Delta concierge was very rude to everyone. But other than that it was fine.

Related info for your journey

Find useful and relevant information for your journey from Melbourne to South Carolina. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly from for flights from Melbourne to South Carolina?

    Located just 2.7 mi from the city center, Melbourne (MLB) is the airport most travelers will use when flying to South Carolina from Melbourne.

  • What are the most popular routes from Melbourne, Florida to South Carolina?

    While some choose either Melbourne - Charleston or Melbourne - Greenville, Melbourne - Charlotte Douglas is the most popular route from Melbourne, Florida to South Carolina.

  • Can I find deals for flights from Melbourne to South Carolina that include hotel bookings?

    Yes. In addition to deals on Melbourne to South Carolina flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Melbourne to South Carolina?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Melbourne to South Carolina.

  • Can I find deals for business class flights from Melbourne to South Carolina?

    Yes. Cheapflights offers flight deals from Melbourne to South Carolina by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Melbourne, Florida to South Carolina?

    Currently, August is the cheapest month in which you can book a flight from Melbourne, Florida to South Carolina (average of $217). Flying from Melbourne, Florida to South Carolina in March is currently the most expensive (average of $335). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Browse thousands of different options on Cheapflights for your next trip

Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.

Alternative routes for Melbourne to South Carolina

See prices for flight routes from nearby airports that may be better suited for you.
Fort Lauderdale to Newark flights
Orlando to Newark flights
Fort Lauderdale to LaGuardia flights
Fort Lauderdale to John F Kennedy Intl flights
Miami to LaGuardia flights
Miami to Newark flights
Miami to John F Kennedy Intl flights
Orlando to LaGuardia flights
Tampa to John F Kennedy Intl flights
Tampa to Newark flights
Orlando to John F Kennedy Intl flights
Orlando to Seattle flights
West Palm Beach to John F Kennedy Intl flights
Tampa to LaGuardia flights
Orlando to Las Vegas flights
Tampa to Seattle flights
Orlando to Dallas/Fort Worth flights
Fort Lauderdale to Las Vegas flights
Orlando to Boston flights
Miami to Los Angeles flights
Orlando to Hobby flights
Orlando to Los Angeles flights
Miami to O'Hare Intl flights
Fort Lauderdale to Atlanta flights
Fort Lauderdale to O'Hare Intl flights
Orlando to Denver flights
Orlando to O'Hare Intl flights
Tampa to Las Vegas flights
Fort Lauderdale to Dallas/Fort Worth flights
Miami to Atlanta flights
Fort Lauderdale to Boston flights
West Palm Beach to Newark flights
Miami to Denver flights
Miami to Boston flights
Tampa to O'Hare Intl flights
Miami to Seattle flights
Tampa to Denver flights
Tampa to Boston flights
Fort Lauderdale to Los Angeles flights
Fort Lauderdale to Denver flights
Fort Lauderdale to Seattle flights
Fort Lauderdale to Baltimore flights
Tampa to Dallas/Fort Worth flights
Jacksonville to Newark flights
Jacksonville to John F Kennedy Intl flights
Miami to Dallas/Fort Worth flights
Tampa to Los Angeles flights
West Palm Beach to LaGuardia flights
Miami to Las Vegas flights
Orlando to San Francisco flights

Top 2 airlines flying from Melbourne to South Carolina

Discover the top 2 airlines that operate flights from Melbourne to South Carolina. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated abril 17, 2025.
AirlineCheapestAverageFlexibilityOn-time
DeltaCheapest$178Average$370FlexibilityNo cancel feeOn-timeN/A
American AirlinesCheapest$256Average$423FlexibilityNo cancel feeOn-time71%

100% Free

Cheapflights is completely free to use, so you can start saving the moment you arrive.

Book with Flexibility

Our users can plan ahead with confidence and find flights with no change fees

Travel Smart

Millions of people come to us for their flight needs every year. We help make travel planning easy by providing useful insights and data-driven graphs that can inform your decisions.