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$130+ Cheap flights from Medford (MFR) to South Carolina

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 5/13. Fares are subject to change and may not be available on all flights or dates of travel.
MFR — CHS
Apr 2 — Apr 91
Wed 4/2
Wed 4/9
1 adult, Economy
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Cheap flight deals from Medford to South Carolina

Keep the following information in mind while searching for Medford to South Carolina flight deals. Data was last updated March 28, 2025.

Round-trip from

$356
(United Airlines)

One-way from

$130
(Delta)
From Medford to South Carolina
Search Deals
One-way flight from Medford to South Carolina
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Find flight deals from Medford to South Carolina

Cheapest flights from Medford to South Carolina
Explore the most affordable flight options available from Medford to South Carolina. Find the lowest fares from popular airlines and budget airlines, with prices last updated on March 28, 2025.

This United Airlines deal was found by Cheapflights users on 3/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 4/126:35 pmMFR - GSP
2 stops12h 34mUnited Airlines
Wed 4/164:26 pmGSP - MFR
1 stop8h 00mUnited Airlines
Deal found 3/27$356
This Delta deal was found by Cheapflights users on 3/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/306:00 amMFR - CLT
1 stop7h 35mDelta
Tue 6/35:45 pmCLT - MFR
1 stop9h 07mDelta
Deal found 3/26$457
This United Airlines deal was found by Cheapflights users on 3/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/296:28 pmMFR - CAE
2 stops12h 31mUnited Airlines
Mon 6/25:35 pmCAE - MFR
2 stops21h 24mUnited Airlines
Deal found 3/26$498
This United Airlines deal was found by Cheapflights users on 3/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 5/55:00 amMFR - CLT
1 stop14h 45mUnited Airlines
Tue 5/68:15 amCLT - MFR
1 stop7h 48mUnited Airlines
Deal found 3/26$592
This American Airlines deal was found by Cheapflights users on 3/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 4/255:20 amMFR - CLT
1 stop7h 11mAmerican Airlines
Mon 4/286:08 pmCLT - MFR
1 stop7h 44mAmerican Airlines
Deal found 3/26$633

Cheapflights Fare Finder

Customize your flight search to find flights from Medford to South Carolina that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated March 28, 2025.
Use the filters below to find and compare flights from Medford to South Carolina that are best for you.

Fly from

Medford

Fly to

South Carolina

Route

Depart

Return

Price

MedfordGreenville

MFR - GSP

MFRGSP

Medford

Sat 4/12

6:35 pm-10:09 am

2 stops12h 34m

Greenville

Wed 4/16

4:26 pm-9:26 pm

1 stop8h 00m

$356

MedfordCharlotte

MFR - CLT

MFRCLT

Medford

Fri 5/30

6:00 am-4:35 pm

1 stop7h 35m

Charlotte Douglas

Tue 6/3

5:45 pm-11:52 pm

1 stop9h 07m

$457

MedfordColumbia

MFR - CAE

MFRCAE

Medford

Thu 5/29

6:28 pm-9:59 am

2 stops12h 31m

Columbia Metropolitan

Mon 6/2

5:35 pm-11:59 am

2 stops21h 24m

$498

MedfordCharlotte

MFR - CLT

MFRCLT

Medford

Mon 5/5

5:00 am-10:45 pm

1 stop14h 45m

Charlotte Douglas

Tue 5/6

8:15 am-1:03 pm

1 stop7h 48m

$592

MedfordCharlotte

MFR - CLT

MFRCLT

Medford

Fri 4/25

5:20 am-3:31 pm

1 stop7h 11m

Charlotte Douglas

Mon 4/28

6:08 pm-10:52 pm

1 stop7h 44m

$633

MedfordGreenville

MFR - GSP

MFRGSP

Medford

Tue 5/13

5:10 pm-9:14 am

2 stops13h 04m

$130

MedfordGreenville

MFR - GSP

MFRGSP

Medford

Tue 5/13

2:05 pm-9:52 am

3 stops16h 47m

$185

MedfordCharlotte

MFR - CLT

MFRCLT

Medford

Wed 4/30

11:30 am-10:05 am

2 stops19h 35m

$222

MedfordCharlotte

MFR - CLT

MFRCLT

Medford

Sat 5/3

5:20 am-3:31 pm

1 stop7h 11m

$229

MedfordCharlotte

MFR - CLT

MFRCLT

Medford

Wed 4/30

5:00 am-3:16 pm

1 stop7h 16m

$279

Flights are sorted by cheapest round-trip flights first.

Deals found on 3/28

Best time to book a flight from Medford to South Carolina

Have a flexible travel schedule? Discover the best time to fly to South Carolina from Medford with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Medford to South Carolina

What is the cheapest month to book a flight from Medford to South Carolina?

Currently, August is the cheapest month in which you can book a flight from Medford to South Carolina (average of $217). Flying from Medford to South Carolina in March is currently the most expensive (average of $335). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from MFR to SC?

Find hourly flight availability from Medford to South Carolina. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated March 28, 2025.

When flying from Medford to South Carolina, the time of day you decide to fly out makes little to no difference towards the overall price you’ll pay on tickets.

Rainfall in South Carolina by month

Plan your trip to South Carolina by taking into account the average rainfall totals by month.

In terms of precipitation, rainfall in South Carolina ranges from 3.0 - 6.5 inches per month. July is typically the wettest month, when rainfall can reach 6.5 in. November is typically the driest time to visit South Carolina when rainfall is around 3.0 in.

Temperature in South Carolina by month

Plan your trip to South Carolina by taking into account the average temperature totals by month.

If weather is an important factor for your trip to South Carolina, use this chart to help with planning. For those seeking warmer temperatures, July is the ideal time of year to visit, when temperatures reach an average of 78.8 F. Travelers looking to avoid the cold should look outside of January, when temperatures are typically at their lowest (around 44.6 F).

Reviews of airlines servicing South Carolina

Get insights into the airlines that provide service to South Carolina. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to South Carolina. Reviews last updated March 28, 2025.
Delta
8.0
Very good
7,897 reviews

Crew

8.5

Boarding

8.2

Comfort

8.0

Food

7.3

Overall

8.0

Entertainment

7.9

Reviews

1 / 20
10.0
Excellent

Aaron,Oct 2024

TUS - LAX

Delta has consistently been the best U.S. airline for my travels and this flight was no exception
Delta
8.0
Very good
7,897 reviews
Delta
8.0
Very good
7,897 reviews

Crew

8.5

Boarding

8.2

Comfort

8.0

Food

7.3

Overall

8.0

Entertainment

7.9

Reviews

1 / 20
10.0
Excellent

Aaron,Oct 2024

TUS - LAX

Delta has consistently been the best U.S. airline for my travels and this flight was no exception
United Airlines
7.4
Good
8,603 reviews
Delta
8.0
Very good
7,897 reviews

Crew

8.5

Boarding

8.2

Comfort

8.0

Food

7.3

Overall

8.0

Entertainment

7.9

Reviews

1 / 20
10.0
Excellent

Aaron,Oct 2024

TUS - LAX

Delta has consistently been the best U.S. airline for my travels and this flight was no exception
American Airlines
7.2
Good
10,000 reviews
Delta
8.0
Very good
7,897 reviews

Crew

8.5

Boarding

8.2

Comfort

8.0

Food

7.3

Overall

8.0

Entertainment

7.9

Reviews

1 / 20
10.0
Excellent

Aaron,Oct 2024

TUS - LAX

Delta has consistently been the best U.S. airline for my travels and this flight was no exception

Related info for your journey

Find useful and relevant information for your journey from Medford to South Carolina. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly from for flights from Medford to South Carolina?

    Medford (MFR), located 3.0 mi from the city center, is the airport you fly out of when you book flights from Medford to South Carolina.

  • What are the cheapest airlines to fly from Medford to South Carolina one-way?

    To fly one-way, consider booking your trip with Delta, which is currently one of the cheapest options available, starting at $130. United Airlines flights start at $185 while deals on American Airlines start at $229 one-way.

  • What are the most popular routes from Medford to South Carolina?

    The most popular flight routes from Medford to South Carolina are Medford - Charlotte Douglas, Medford - Greenville and Medford - Columbia Metropolitan.

  • Can I find deals for flights from Medford to South Carolina that include hotel bookings?

    Yes. In addition to deals on Medford to South Carolina flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Medford to South Carolina?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Medford to South Carolina.

  • Can I find deals for business class flights from Medford to South Carolina?

    Yes. Cheapflights offers flight deals from Medford to South Carolina by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Medford to South Carolina?

    Currently, August is the cheapest month in which you can book a flight from Medford to South Carolina (average of $217). Flying from Medford to South Carolina in March is currently the most expensive (average of $335). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

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Top 2 airlines flying from Medford to South Carolina

Discover the top 2 airlines that operate flights from Medford to South Carolina. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated March 28, 2025.
AirlineCheapestAverageFlexibilityOn-time
United AirlinesCheapest$254Average$589FlexibilityNo cancel feeOn-time69%
Alaska AirlinesCheapest$449Average$571FlexibilityNo cancel feeOn-time75%
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