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South Carolina

$354+ Cheap flights from Manchester (MAN) to South Carolina

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 2/25. Fares are subject to change and may not be available on all flights or dates of travel.
MAN — CHS
Jan 11 — Jan 181
Sun 1/11
Sun 1/18
1 adult, Economy
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Cheap flight deals from Manchester to South Carolina

Cheapest flights from Manchester to South Carolina
Explore the most affordable flight options available from Manchester to South Carolina. Find the lowest fares from popular airlines and budget airlines, with prices last updated on December 12, 2025.

This Kiwi.com deal was found by Cheapflights users on 12/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/1110:25 amMAN - CLT
1 stop14h 35mMultiple Airlines
Thu 12/182:22 pmCLT - MAN
1 stop12h 33mMultiple Airlines
Deal found 12/10$1,330
This Cheapflightsfares deal was found by Cheapflights users on 12/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/156:25 amMAN - GSP
2 stops22h 34mLufthansa
Wed 1/72:55 pmGSP - MAN
2 stops21h 00mLufthansa
Deal found 12/11$1,524
This Delta deal was found by Cheapflights users on 12/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/151:00 pmMAN - GSP
2 stops27h 15mDelta
Wed 1/75:12 pmGSP - MAN
1 stop12h 18mDelta
Deal found 12/11$1,549
This Expedia deal was found by Cheapflights users on 12/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/111:30 pmMAN - CLT
1 stop15h 12mVirgin Atlantic
Thu 12/1811:38 amCLT - MAN
2 stops15h 17mVirgin Atlantic
Deal found 12/10$1,644
This oojo deal was found by Cheapflights users on 12/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure oojo is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/119:45 amMAN - CLT
2 stops16h 59mBritish Airways
Thu 12/186:13 pmCLT - MAN
2 stops15h 07mBritish Airways
Deal found 12/10$1,645
This Mytrip deal was found by Cheapflights users on 12/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/207:20 pmMAN - CLT
3 stops30h 37mMultiple Airlines
Fri 12/266:50 pmCLT - MAN
2 stops24h 35mMultiple Airlines
Deal found 12/11$1,672
This Cheapflightsfares deal was found by Cheapflights users on 12/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/156:25 amMAN - GSP
2 stops22h 34mLufthansa
Tue 12/3011:55 amGSP - MAN
2 stops21h 55mLufthansa
Deal found 12/11$1,838
This Delta deal was found by Cheapflights users on 12/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/151:00 pmMAN - GSP
2 stops27h 15mDelta
Tue 12/3010:05 amGSP - MAN
1 stop19h 25mDelta
Deal found 12/11$1,859
This American Airlines deal was found by Cheapflights users on 12/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/209:50 amMAN - CLT
2 stops16h 21mAmerican Airlines
Fri 12/2611:00 pmCLT - MAN
1 stop12h 35mAmerican Airlines
Deal found 12/11$1,968
This Booking.com deal was found by Cheapflights users on 12/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Booking.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/209:50 amMAN - CLT
2 stops17h 05mBritish Airways
Fri 12/266:00 pmCLT - MAN
2 stops12h 55mBritish Airways
Deal found 12/11$2,001
This Cheapflightsfares deal was found by Cheapflights users on 12/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/206:45 amMAN - CLT
1 stop15h 10mLufthansa
Fri 12/266:50 pmCLT - MAN
1 stop23h 30mLufthansa
Deal found 12/11$2,128
This FlightHub deal was found by Cheapflights users on 12/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure FlightHub is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/203:40 pmMAN - CLT
2 stops33h 05mAer Lingus
Sun 1/42:52 pmCLT - MAN
2 stops19h 28mAer Lingus
Deal found 12/11$2,166

Find flight deals from Manchester to South Carolina

Keep the following information in mind while searching for Manchester to South Carolina flight deals. Data was last updated December 12, 2025.

Most accurate provider

Expedia
2 stars

Most trusted provider

Expedia
3 stars

Round-trip from

$694
(Mytrip)

One-way from

$354
(Kiwi.com)

Popular in

December

Cheapest in

February

Average price

$2,309
Provider with most accurate pricing for Manchester-Myrtle Beach Intl flight deals.
Search Deals
Provider most trusted by Cheapflights users for Manchester-Myrtle Beach Intl flights.
Search Deals
From Manchester to South Carolina
Search Deals
One-way flight from Manchester to South Carolina
Search Deals
Highest demand for flights based on searches. 22% potential increase in price ($312 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 11% potential price decrease ($111 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in December 2025
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from Manchester to South Carolina that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated December 12, 2025.
Use the filters below to find and compare flights from Manchester to South Carolina that are best for you.

Fly from

Manchester

Fly to

South Carolina

Route

Depart

Return

Price

ManchesterCharlotte

MAN - CLT

MANCLT

Manchester

Mon 1/12

9:15 am-11:59 pm

3 stops43h 44m

Charlotte Douglas

Mon 1/26

7:43 pm-10:45 am

3 stops34h 02m

$694

ManchesterCharlotte

MAN - CLT

MANCLT

Manchester

Sun 1/25

6:20 am-4:55 pm

2 stops15h 35m

Charlotte Douglas

Sun 2/1

6:50 pm-4:20 pm

2 stops16h 30m

$719

ManchesterCharlotte

MAN - CLT

MANCLT

Manchester

Fri 3/20

8:55 pm-11:53 pm

2 stops30h 58m

Charlotte Douglas

Wed 3/25

9:21 am-12:15 pm

2 stops22h 54m

$726

ManchesterCharlotte

MAN - CLT

MANCLT

Manchester

Thu 2/5

7:15 pm-11:54 pm

2 stops33h 39m

Charlotte Douglas

Mon 2/9

6:00 am-6:35 pm

2 stops31h 35m

$849

ManchesterSavannah

MAN - SAV

MANSAV

Manchester

Fri 4/24

12:45 pm-9:30 pm

2 stops37h 45m

Savannah/Hilton Head

Fri 5/8

7:25 am-10:00 am

2 stops21h 35m

$917

ManchesterCharleston

MAN - CHS

MANCHS

Manchester

Wed 4/29

7:05 am-7:03 pm

2 stops16h 58m

Charleston

Thu 5/14

11:17 am-9:45 am

2 stops17h 28m

$925

ManchesterCharleston

MAN - CHS

MANCHS

Manchester

Wed 4/29

10:55 am-8:39 pm

2 stops14h 44m

Charleston

Thu 5/14

4:29 pm-11:35 am

2 stops14h 06m

$925

ManchesterMyrtle Beach

MAN - MYR

MANMYR

Manchester

Sun 1/25

6:25 am-9:03 am

3 stops31h 38m

Myrtle Beach Intl

Sun 2/1

10:00 am-9:35 am

3 stops18h 35m

$930

ManchesterSavannah

MAN - SAV

MANSAV

Manchester

Mon 1/26

6:00 am-9:36 pm

2 stops20h 36m

Savannah/Hilton Head

Mon 2/2

2:05 pm-5:00 pm

2 stops21h 55m

$933

ManchesterCharleston

MAN - CHS

MANCHS

Manchester

Wed 4/29

11:00 am-11:51 pm

1 stop17h 51m

Charleston

Thu 5/14

2:25 pm-8:10 am

1 stop12h 45m

$934

Flights are sorted by cheapest round-trip flights first.

Deals found on 12/11

Showing 1-10 of 54 results
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Best time to book a flight from Manchester to South Carolina

Have a flexible travel schedule? Discover the best time to fly to South Carolina from Manchester with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Manchester to South Carolina

What is the cheapest month to book a flight from Manchester to South Carolina?

Currently, February is the cheapest month in which you can book a flight from Manchester to South Carolina (average of $699). Flying from Manchester to South Carolina in June is currently the most expensive (average of $843). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

Related info for your journey

Find useful and relevant information for your journey from Manchester to South Carolina. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly from for flights from Manchester to South Carolina?

    Located just 8.9 mi from the city center, Manchester (MAN) is the airport most travelers will use when flying to South Carolina from Manchester.

  • How long is the flight from Manchester to South Carolina?

    For as low as $925, Scandinavian Airlines can have you in South Carolina from Manchester in 16h 58m. There are 3948 mi between Manchester and South Carolina. When browsing for deals, the options you’ll see will be for both nonstop flights and flights with stops.

  • What are the most popular routes from Manchester to South Carolina?

    The most popular route from Manchester to South Carolina is Manchester - Charlotte Douglas. You may also consider Manchester - Myrtle Beach Intl or Manchester - Charleston.

  • Can I find deals for flights from Manchester to South Carolina that include hotel bookings?

    Yes. In addition to deals on Manchester to South Carolina flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Manchester to South Carolina?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Manchester to South Carolina.

  • Can I find deals for business class flights from Manchester to South Carolina?

    Yes. Cheapflights offers flight deals from Manchester to South Carolina by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Manchester to South Carolina?

    Currently, February is the cheapest month in which you can book a flight from Manchester to South Carolina (average of $699). Flying from Manchester to South Carolina in June is currently the most expensive (average of $843). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

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Alternative routes for Manchester to South Carolina

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