South Carolina

$56+ Cheap flights from Maine to South Carolina

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 5/1. Fares are subject to change and may not be available on all flights or dates of travel.
PWM — CHS
Apr 22 — Apr 291
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Cheap flight deals from Maine to South Carolina

Keep the following information in mind while searching for Maine to South Carolina flight deals. Data was last updated April 17, 2025.

Most accurate provider

FlightHub
3 stars

Most trusted provider

eDreams
3 stars

Round-trip from

$76
(Cheapflightsfares)

One-way from

$56
(Cheapflightsfares)

Popular in

April

Cheapest in

December

Average price

$466

Good round-trip deal

$94 or less

Good one-way deal

$79 or less
Provider with most accurate pricing for Portland-Myrtle Beach Intl flight deals.
Provider most trusted by Cheapflights users for Portland-Myrtle Beach Intl flights.
From Maine to South Carolina
One-way flight from Maine to South Carolina
Highest demand for flights based on searches. 8% potential increase in price ($36 potential increase over avg. RT price).
Cheapest flight prices on average. 1% potential price decrease ($7 potential savings vs. average RT price).
Average for round-trip flights in April 2025
Price to beat on a round-trip flight from Maine to South Carolina.
Price to beat on a one-way flight from Maine to South Carolina.

Find flight deals from Maine to South Carolina

Cheapest flights from Maine to South Carolina
Explore the most affordable flight options available from Maine to South Carolina. Find the lowest fares from popular airlines and budget airlines, with prices last updated on April 17, 2025.

This Cheapflightsfares deal was found by Cheapflights users on 4/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/301:31 pmBOS - CHS
Nonstop2h 25mSpirit Airlines
Thu 5/14:51 pmCHS - BOS
Nonstop2h 13mSpirit Airlines
Deal found 4/16$76
This Cheapflightsfares deal was found by Cheapflights users on 4/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/19:59 pmBOS - MYR
Nonstop2h 14mSpirit Airlines
Mon 5/55:30 amMYR - BOS
Nonstop2h 10mSpirit Airlines
Deal found 4/16$112
This Booking.com deal was found by Cheapflights users on 4/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Booking.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/2211:31 amBOS - SAV
Nonstop2h 40mAllegiant Air
Sun 5/258:15 amSAV - BOS
Nonstop2h 26mAllegiant Air
Deal found 4/17$114
This Mytrip deal was found by Cheapflights users on 4/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 5/256:00 amBOS - SAV
1 stop13h 33mMultiple Airlines
Thu 5/298:15 amSAV - BOS
Nonstop2h 26mMultiple Airlines
Deal found 4/17$134
This Delta deal was found by Cheapflights users on 4/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/312:35 pmBOS - CHS
Nonstop2h 31mDelta
Sat 5/104:25 pmCHS - BOS
Nonstop2h 25mDelta
Deal found 4/16$147
This JetBlue deal was found by Cheapflights users on 4/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure JetBlue is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/35:30 pmBOS - CHS
Nonstop2h 36mJetBlue
Tue 5/65:55 pmCHS - BOS
Nonstop2h 23mJetBlue
Deal found 4/16$148
This Cheapflightsfares deal was found by Cheapflights users on 4/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/143:49 pmBOS - CLT
1 stop6h 11mSpirit Airlines
Sun 5/1811:58 amCLT - BOS
Nonstop2h 28mSpirit Airlines
Deal found 4/15$154
This American Airlines deal was found by Cheapflights users on 4/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/35:59 amBOS - CHS
1 stop4h 28mAmerican Airlines
Tue 5/65:15 pmCHS - BOS
1 stop4h 38mAmerican Airlines
Deal found 4/15$166
This United Airlines deal was found by Cheapflights users on 4/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 5/115:30 amBOS - CHS
1 stop4h 41mUnited Airlines
Tue 5/136:30 amCHS - BOS
2 stops7h 49mUnited Airlines
Deal found 4/16$172
This Mytrip deal was found by Cheapflights users on 4/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/172:25 pmBOS - MYR
Nonstop2h 12mMultiple Airlines
Sat 5/248:58 pmMYR - BOS
1 stop12h 27mMultiple Airlines
Deal found 4/17$182
This Mytrip deal was found by Cheapflights users on 4/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 6/74:49 pmBOS - CAE
1 stop20h 53mMultiple Airlines
Mon 6/92:50 pmCAE - BOS
1 stop8h 39mMultiple Airlines
Deal found 4/17$186
This JetBlue deal was found by Cheapflights users on 4/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure JetBlue is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 5/52:53 pmBOS - SAV
Nonstop2h 42mJetBlue
Mon 5/1211:05 amSAV - BOS
Nonstop2h 28mJetBlue
Deal found 4/17$187

Cheapflights Fare Finder

Customize your flight search to find flights from Maine to South Carolina that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated April 17, 2025.
Use the filters below to find and compare flights from Maine to South Carolina that are best for you.

Fly from

Maine

Fly to

South Carolina

Route

Depart

Return

Price

BostonCharleston

BOS - CHS

BOSCHS

Boston Logan Intl

Wed 4/30

1:31 pm-3:56 pm

Nonstop2h 25m

Charleston

Thu 5/1

4:51 pm-7:04 pm

Nonstop2h 13m

$76

BostonMyrtle Beach

BOS - MYR

BOSMYR

Boston Logan Intl

Thu 5/1

9:59 pm-12:13 am

Nonstop2h 14m

Myrtle Beach Intl

Mon 5/5

5:30 am-7:40 am

Nonstop2h 10m

$112

BostonSavannah

BOS - SAV

BOSSAV

Boston Logan Intl

Thu 5/22

11:31 am-2:11 pm

Nonstop2h 40m

Savannah/Hilton Head

Sun 5/25

8:15 am-10:41 am

Nonstop2h 26m

$114

BostonSavannah

BOS - SAV

BOSSAV

Boston Logan Intl

Sun 5/25

6:00 am-7:33 pm

1 stop13h 33m

Savannah/Hilton Head

Thu 5/29

8:15 am-10:41 am

Nonstop2h 26m

$134

BostonCharleston

BOS - CHS

BOSCHS

Boston Logan Intl

Sat 5/3

5:30 pm-8:06 pm

Nonstop2h 36m

Charleston

Fri 5/9

8:45 pm-11:07 pm

Nonstop2h 22m

$147

BostonCharlotte

BOS - CLT

BOSCLT

Boston Logan Intl

Wed 5/14

3:49 pm-10:00 pm

1 stop6h 11m

Charlotte Douglas

Sun 5/18

11:58 am-2:26 pm

Nonstop2h 28m

$154

BostonCharleston

BOS - CHS

BOSCHS

Boston Logan Intl

Sat 5/3

5:59 am-10:27 am

1 stop4h 28m

Charleston

Tue 5/6

5:15 pm-9:53 pm

1 stop4h 38m

$166

BostonCharleston

BOS - CHS

BOSCHS

Boston Logan Intl

Sun 5/11

5:30 am-10:11 am

1 stop4h 41m

Charleston

Tue 5/13

6:30 am-2:19 pm

2 stops7h 49m

$172

BostonMyrtle Beach

BOS - MYR

BOSMYR

Boston Logan Intl

Sat 5/17

2:25 pm-4:37 pm

Nonstop2h 12m

Myrtle Beach Intl

Sat 5/24

8:58 pm-9:25 am

1 stop12h 27m

$182

BostonColumbia

BOS - CAE

BOSCAE

Boston Logan Intl

Sat 6/7

4:49 pm-1:42 pm

1 stop20h 53m

Columbia Metropolitan

Mon 6/9

2:50 pm-11:29 pm

1 stop8h 39m

$186

Flights are sorted by cheapest round-trip flights first.

Deals found on 4/16

Showing 1-10 of 60 results
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Best time to book a flight from Maine to South Carolina

Have a flexible travel schedule? Discover the best time to fly to South Carolina from Maine with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Maine to South Carolina

What is the cheapest month to book a flight from Maine to South Carolina?

Currently, August is the cheapest month in which you can book a flight from Maine to South Carolina (average of $217). Flying from Maine to South Carolina in March is currently the most expensive (average of $335). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from ME to SC?

Find hourly flight availability from Maine to South Carolina. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated April 17, 2025.

Regardless of the time of day you decide to fly, the ticket price will remain around the same. Book flights from Maine to South Carolina as you normally would.

Rainfall in South Carolina by month

Plan your trip to South Carolina by taking into account the average rainfall totals by month.

In terms of precipitation, rainfall in South Carolina ranges from 3.0 - 6.5 inches per month. July is typically the wettest month, when rainfall can reach 6.5 in. November is typically the driest time to visit South Carolina when rainfall is around 3.0 in.

Temperature in South Carolina by month

Plan your trip to South Carolina by taking into account the average temperature totals by month.

If weather is an important factor for your trip to South Carolina, use this chart to help with planning. For those seeking warmer temperatures, July is the ideal time of year to visit, when temperatures reach an average of 78.8 F. Travelers looking to avoid the cold should look outside of January, when temperatures are typically at their lowest (around 44.6 F).

Reviews of airlines servicing South Carolina

Get insights into the airlines that provide service to South Carolina. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to South Carolina. Reviews last updated April 17, 2025.
Read reviews from past customers who have flown Breeze Airways, Southwest and Delta from Maine to South Carolina. Reviews also offer insight into each airline's entertainment options, comfort, food, crew/service, and boarding process.

Boarding

8.3

Overall

8.1

Food

6.7

Crew

8.8

Comfort

8.2

Entertainment

6.6

Reviews

1 / 11
10.0
Excellent

Dena,Dec 2024

LAS - BDL

It was comfortable and the crew was great! A few free snacks offered would be nice!

Boarding

8.3

Overall

8.1

Food

6.7

Crew

8.8

Comfort

8.2

Entertainment

6.6

Reviews

1 / 11
10.0
Excellent

Dena,Dec 2024

LAS - BDL

It was comfortable and the crew was great! A few free snacks offered would be nice!

Boarding

8.3

Overall

8.1

Food

6.7

Crew

8.8

Comfort

8.2

Entertainment

6.6

Reviews

1 / 11
10.0
Excellent

Dena,Dec 2024

LAS - BDL

It was comfortable and the crew was great! A few free snacks offered would be nice!
8.0
Very good

Boarding

8.3

Overall

8.1

Food

6.7

Crew

8.8

Comfort

8.2

Entertainment

6.6

Reviews

1 / 11
10.0
Excellent

Dena,Dec 2024

LAS - BDL

It was comfortable and the crew was great! A few free snacks offered would be nice!

Boarding

8.3

Overall

8.1

Food

6.7

Crew

8.8

Comfort

8.2

Entertainment

6.6

Reviews

1 / 11
10.0
Excellent

Dena,Dec 2024

LAS - BDL

It was comfortable and the crew was great! A few free snacks offered would be nice!

Boarding

8.3

Overall

8.1

Food

6.7

Crew

8.8

Comfort

8.2

Entertainment

6.6

Reviews

1 / 11
10.0
Excellent

Dena,Dec 2024

LAS - BDL

It was comfortable and the crew was great! A few free snacks offered would be nice!

Related info for your journey

Find useful and relevant information for your journey from Maine to South Carolina. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
  • How popular is this Maine to South Carolina flight route?

  • What are the cheapest airlines to fly from Maine to South Carolina one-way?

    $56 is the cheapest one-way deal found within the past few days, from Spirit Airlines. You may also be able to find cheap deals on United Airlines and JetBlue, with prices starting from $84 and $94, respectively.

  • Can I find deals for flights from Maine to South Carolina that include hotel bookings?

    Yes. In addition to deals on Maine to South Carolina flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Maine to South Carolina?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Maine to South Carolina.

  • Can I find deals for business class flights from Maine to South Carolina?

    Yes. Cheapflights offers flight deals from Maine to South Carolina by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Maine to South Carolina?

    Currently, August is the cheapest month in which you can book a flight from Maine to South Carolina (average of $217). Flying from Maine to South Carolina in March is currently the most expensive (average of $335). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Browse thousands of different options on Cheapflights for your next trip

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Alternative routes for Maine to South Carolina

See prices for flight routes from nearby airports that may be better suited for you.

Top 5 airlines flying from Maine to South Carolina

Discover the top 5 airlines that operate flights from Maine to South Carolina. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated April 17, 2025.
AirlineCheapestAverageFlexibilityOn-time
Breeze AirwaysCheapest$90Average$189FlexibilityNo cancel feeOn-timeN/A
DeltaCheapest$171Average$391FlexibilityNo cancel feeOn-timeN/A
American AirlinesCheapest$182Average$428FlexibilityNo cancel feeOn-time71%
United AirlinesCheapest$188Average$430FlexibilityNo cancel feeOn-time69%
SouthwestCheapest$236Average$430FlexibilityNo cancel feeOn-time63%

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