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South Carolina

$84+ Cheap flights from Louisville (SDF) to South Carolina

This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 6/2. Fares are subject to change and may not be available on all flights or dates of travel.
SDF — CHS
Feb 25 — Mar 41
Tue 2/25
Tue 3/4
1 adult, Economy
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Cheap flight deals from Louisville to South Carolina

Keep the following information in mind while searching for Louisville to South Carolina flight deals. Data was last updated February 20, 2025.

Most accurate provider

FlightHub
3 stars

Most trusted provider

FlightHub
3 stars

Round-trip from

$84
(Booking.com)

One-way from

$84
(Delta)

Popular in

December

Cheapest in

July

Average price

$376

Good round-trip deal

$131 or less
Provider with most accurate pricing for Louisville Intl-Myrtle Beach Intl flight deals.
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Provider most trusted by Cheapflights users for Louisville Intl-Myrtle Beach Intl flights.
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From Louisville Intl to South Carolina
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One-way flight from Louisville Intl to South Carolina
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Highest demand for flights based on searches. 15% potential increase in price ($58 potential increase over avg. RT price).
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Cheapest flight prices on average. 3% potential price decrease ($12 potential savings vs. average RT price).
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Average for round-trip flights in February 2025
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Price to beat on a round-trip flight from Louisville Intl to South Carolina.
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Find flight deals from Louisville to South Carolina

Cheapest flights from Louisville to South Carolina
Explore the most affordable flight options available from Louisville to South Carolina. Find the lowest fares from popular airlines and budget airlines, with prices last updated on February 20, 2025.

This Booking.com deal was found by Cheapflights users on 2/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Booking.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 6/25:23 pmSDF - SAV
Nonstop1h 33mAllegiant Air
Fri 6/612:02 pmSAV - SDF
Nonstop1h 37mAllegiant Air
Deal found 2/19$84
This Cheapflightsfares deal was found by Cheapflights users on 2/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 3/216:43 pmSDF - MYR
Nonstop1h 26mSpirit Airlines
Mon 3/244:13 pmMYR - SDF
Nonstop1h 35mSpirit Airlines
Deal found 2/20$87
This Cheapflightsfares deal was found by Cheapflights users on 2/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 4/56:00 amSDF - CHS
1 stop10h 34mSpirit Airlines
Thu 4/1011:14 amCHS - SDF
1 stop11h 03mSpirit Airlines
Deal found 2/20$131
This Cheapflightsfares deal was found by Cheapflights users on 2/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 6/74:58 pmSDF - MYR
Nonstop1h 27mAllegiant Air
Sat 6/147:15 pmMYR - SDF
Nonstop1h 34mAllegiant Air
Deal found 2/20$138
This Mytrip deal was found by Cheapflights users on 2/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 3/216:00 amSDF - CLT
1 stop18h 32mSpirit Airlines
Tue 3/256:07 pmCLT - SDF
1 stop22h 31mSpirit Airlines
Deal found 2/19$156
This Delta deal was found by Cheapflights users on 2/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 5/197:30 pmSDF - CLT
1 stop4h 26mDelta
Wed 5/218:15 pmCLT - SDF
1 stop3h 41mDelta
Deal found 2/20$157
This Mytrip deal was found by Cheapflights users on 2/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 3/2111:03 amSDF - MYR
3 stops33h 19mMultiple Airlines
Mon 3/244:13 pmMYR - SDF
Nonstop1h 35mMultiple Airlines
Deal found 2/20$179
This Mytrip deal was found by Cheapflights users on 2/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 3/176:22 pmSDF - CLT
2 stops22h 47mMultiple Airlines
Mon 3/247:00 amCLT - SDF
1 stop15h 58mMultiple Airlines
Deal found 2/18$180
This Expedia deal was found by Cheapflights users on 2/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/28:35 pmSDF - CHS
Nonstop1h 36mMultiple Airlines
Mon 5/511:06 amCHS - SDF
1 stop11h 11mMultiple Airlines
Deal found 2/19$183
This Mytrip deal was found by Cheapflights users on 2/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 2/2811:03 amSDF - CHS
2 stops11h 54mBreeze Airways
Mon 3/37:00 amCHS - SDF
2 stops7h 45mBreeze Airways
Deal found 2/20$184
This Delta deal was found by Cheapflights users on 2/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 5/127:30 pmSDF - SAV
1 stop4h 34mDelta
Thu 5/157:50 pmSAV - SDF
1 stop4h 06mDelta
Deal found 2/19$217
This Delta deal was found by Cheapflights users on 2/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 4/297:05 amSDF - CHS
1 stop4h 22mDelta
Thu 5/85:30 amCHS - SDF
1 stop4h 02mDelta
Deal found 2/19$217

Find flights from Louisville to South Carolina within your budget

Customize your flight search to find flights from Louisville to South Carolina that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated February 20, 2025.

Fly from

Louisville

Fly to

South Carolina

Route

Depart

Return

Price

LouisvilleMyrtle Beach

SDF - MYR

SDFMYR

Louisville Intl

Sat 4/5

8:26 am-9:50 am

Nonstop1h 24m

Myrtle Beach Intl

Sat 4/12

6:00 am-7:46 am

Nonstop1h 46m

$86

LouisvilleMyrtle Beach

SDF - MYR

SDFMYR

Louisville Intl

Sat 5/17

8:20 pm-9:44 pm

Nonstop1h 24m

Myrtle Beach Intl

Sat 5/24

2:22 pm-3:57 pm

Nonstop1h 35m

$109

LouisvilleCharleston

SDF - CHS

SDFCHS

Louisville Intl

Sat 4/5

6:00 am-4:34 pm

1 stop10h 34m

Charleston

Thu 4/10

11:14 am-10:17 pm

1 stop11h 03m

$131

LouisvilleCharlotte

SDF - CLT

SDFCLT

Louisville Intl

Fri 3/21

6:00 am-12:32 am

1 stop18h 32m

Charlotte Douglas

Tue 3/25

6:07 pm-4:38 pm

1 stop22h 31m

$156

LouisvilleCharlotte

SDF - CLT

SDFCLT

Louisville Intl

Mon 5/19

7:30 pm-11:56 pm

1 stop4h 26m

Charlotte Douglas

Wed 5/21

8:15 pm-11:56 pm

1 stop3h 41m

$157

LouisvilleCharlotte

SDF - CLT

SDFCLT

Louisville Intl

Mon 3/17

6:22 pm-5:09 pm

2 stops22h 47m

Charlotte Douglas

Mon 3/24

7:00 am-10:58 pm

1 stop15h 58m

$180

LouisvilleCharleston

SDF - CHS

SDFCHS

Louisville Intl

Fri 5/2

8:35 pm-10:11 pm

Nonstop1h 36m

Charleston

Mon 5/5

11:06 am-10:17 pm

1 stop11h 11m

$183

LouisvilleSavannah

SDF - SAV

SDFSAV

Louisville Intl

Mon 5/12

7:30 pm-12:04 am

1 stop4h 34m

Savannah/Hilton Head

Thu 5/15

7:50 pm-11:56 pm

1 stop4h 06m

$217

LouisvilleCharleston

SDF - CHS

SDFCHS

Louisville Intl

Tue 4/29

11:08 am-2:46 pm

1 stop3h 38m

Charleston

Tue 5/6

6:45 am-10:03 am

1 stop3h 18m

$217

LouisvilleCharleston

SDF - CHS

SDFCHS

Louisville Intl

Tue 3/25

12:55 pm-8:50 pm

2 stops7h 55m

Charleston

Thu 3/27

6:05 am-11:10 am

1 stop5h 05m

$222

Flights are sorted by cheapest round-trip flights first.

Deals found on 2/20

Showing 1-10 of 50 results
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Best time to book a flight from Louisville to South Carolina

Have a flexible travel schedule? Discover the best time to fly to South Carolina from Louisville with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Travel insights for flights from Louisville to South Carolina

Get recent, data-driven insights about flights from Louisville to South Carolina including ideal travel times, pricing trends, and more.

What is the cheapest month to book a flight from Louisville to South Carolina?

Currently, August is the cheapest month in which you can book a flight from Louisville to South Carolina (average of $217). Flying from Louisville to South Carolina in March is currently the most expensive (average of $335). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from SDF to SC?

Find hourly flight availability from Louisville to South Carolina. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated February 20, 2025.

Regardless of the time of day you decide to fly, the ticket price will remain around the same. Book flights from Louisville to South Carolina as you normally would.

Rainfall in South Carolina by month

Plan your trip to South Carolina by taking into account the average rainfall totals by month.

In terms of precipitation, rainfall in South Carolina ranges from 3.0 - 6.5 inches per month. July is typically the wettest month, when rainfall can reach 6.5 in. November is typically the driest time to visit South Carolina when rainfall is around 3.0 in.

Temperature in South Carolina by month

Plan your trip to South Carolina by taking into account the average temperature totals by month.

If weather is an important factor for your trip to South Carolina, use this chart to help with planning. For those seeking warmer temperatures, July is the ideal time of year to visit, when temperatures reach an average of 78.8 F. Travelers looking to avoid the cold should look outside of January, when temperatures are typically at their lowest (around 44.6 F).

Reviews of airlines servicing South Carolina

Get insights into the airlines that provide service to South Carolina. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to South Carolina. Reviews last updated February 20, 2025.
Get a feel of what it's like to fly with Southwest, Breeze Airways and Delta from Louisville to South Carolina by reading reviews from past customers. Users have also rated airlines in terms of entertainment options, comfort, food, crew/service, and boarding process.
Southwest
8.1
Very good
4,411 reviews

Entertainment

7.6

Food

7.1

Crew

8.7

Overall

8.1

Comfort

8.1

Boarding

8.2

Reviews

1 / 20

2.0
Mediocre

Anonymous,Feb 2025

MCO - STL

Cancelled at last minute, SWA unable to assist in formulating alternate plans. Wound up renting a car and driving 13 hours to beat bad weather forecast at home. Not SWA’s fault that there was significant bad weather across the country.

Southwest
8.1
Very good
4,411 reviews
Southwest
8.1
Very good
4,411 reviews

Entertainment

7.6

Food

7.1

Crew

8.7

Overall

8.1

Comfort

8.1

Boarding

8.2

Reviews

1 / 20

2.0
Mediocre

Anonymous,Feb 2025

MCO - STL

Cancelled at last minute, SWA unable to assist in formulating alternate plans. Wound up renting a car and driving 13 hours to beat bad weather forecast at home. Not SWA’s fault that there was significant bad weather across the country.

Breeze Airways
8.1
Very good
150 reviews
Southwest
8.1
Very good
4,411 reviews

Entertainment

7.6

Food

7.1

Crew

8.7

Overall

8.1

Comfort

8.1

Boarding

8.2

Reviews

1 / 20

2.0
Mediocre

Anonymous,Feb 2025

MCO - STL

Cancelled at last minute, SWA unable to assist in formulating alternate plans. Wound up renting a car and driving 13 hours to beat bad weather forecast at home. Not SWA’s fault that there was significant bad weather across the country.

Delta
8.0
Very good
8,220 reviews
Southwest
8.1
Very good
4,411 reviews

Entertainment

7.6

Food

7.1

Crew

8.7

Overall

8.1

Comfort

8.1

Boarding

8.2

Reviews

1 / 20

2.0
Mediocre

Anonymous,Feb 2025

MCO - STL

Cancelled at last minute, SWA unable to assist in formulating alternate plans. Wound up renting a car and driving 13 hours to beat bad weather forecast at home. Not SWA’s fault that there was significant bad weather across the country.

United Airlines
7.4
Good
8,766 reviews
Southwest
8.1
Very good
4,411 reviews

Entertainment

7.6

Food

7.1

Crew

8.7

Overall

8.1

Comfort

8.1

Boarding

8.2

Reviews

1 / 20

2.0
Mediocre

Anonymous,Feb 2025

MCO - STL

Cancelled at last minute, SWA unable to assist in formulating alternate plans. Wound up renting a car and driving 13 hours to beat bad weather forecast at home. Not SWA’s fault that there was significant bad weather across the country.

Allegiant Air
7.3
Good
765 reviews
Southwest
8.1
Very good
4,411 reviews

Entertainment

7.6

Food

7.1

Crew

8.7

Overall

8.1

Comfort

8.1

Boarding

8.2

Reviews

1 / 20

2.0
Mediocre

Anonymous,Feb 2025

MCO - STL

Cancelled at last minute, SWA unable to assist in formulating alternate plans. Wound up renting a car and driving 13 hours to beat bad weather forecast at home. Not SWA’s fault that there was significant bad weather across the country.

Related info for your journey

Find useful and relevant information for your journey from Louisville to South Carolina. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly from for flights from Louisville to South Carolina?

    Most people fly from Louisville Intl (SDF) if they book a flight from Louisville to South Carolina. Louisville Intl is conveniently located just 5.3 mi from Louisville’s city center.

  • How popular is this Louisville to South Carolina flight route?

    The Louisville Intl to South Carolina flight path was viewed by 15 users in the past month. Keep an eye out for changes in search interest prior to high and low season.

  • What are the cheapest airlines to fly from Louisville to South Carolina one-way?

    For one-way options, check prices for Delta. According to our data, you can fly for as low as $84. Users have also found prices from $87 and $88 on Breeze Airways and Spirit Airlines, respectively.

  • What are the most popular routes from Louisville to South Carolina?

    The most popular flight routes from Louisville to South Carolina are Louisville Intl - Savannah/Hilton Head, Louisville Intl - Charleston and Louisville Intl - Charlotte Douglas.

  • Can I find deals for flights from Louisville to South Carolina that include hotel bookings?

    Yes. In addition to deals on Louisville to South Carolina flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Louisville to South Carolina?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Louisville to South Carolina.

  • Can I find deals for business class flights from Louisville to South Carolina?

    Yes. Cheapflights offers flight deals from Louisville to South Carolina by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Louisville to South Carolina?

    Currently, August is the cheapest month in which you can book a flight from Louisville to South Carolina (average of $217). Flying from Louisville to South Carolina in March is currently the most expensive (average of $335). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

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Alternative routes for Louisville to South Carolina

See prices for flight routes from nearby airports that may be better suited for you.
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Top 7 airlines flying from Louisville to South Carolina

Discover the top 7 airlines that operate flights from Louisville to South Carolina. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated February 20, 2025.
AirlineCheapestAverageFlexibilityOn-time
Breeze AirwaysCheapest$60Average$107FlexibilityNo cancel feeOn-timeN/A
Allegiant AirCheapest$83Average$148FlexibilityNo cancel feeOn-time88%
Spirit AirlinesCheapest$124Average$195FlexibilityNo cancel feeOn-time65%
American AirlinesCheapest$164Average$371FlexibilityNo cancel feeOn-time71%
DeltaCheapest$175Average$314FlexibilityNo cancel feeOn-timeN/A
SouthwestCheapest$231Average$424FlexibilityNo cancel feeOn-time63%
United AirlinesCheapest$245Average$430FlexibilityNo cancel feeOn-time69%
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