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South Carolina

$85+ Cheap flights from Knoxville (TYS) to South Carolina

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 1/11. Fares are subject to change and may not be available on all flights or dates of travel.
TYS — CHS
Dec 24 — Dec 311
Tue 12/24
Tue 12/31
1 adult, Economy
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Cheap flight deals from Knoxville to South Carolina

Discover tips and strategies to find the most affordable flight options for your journey from Knoxville (TYS) to South Carolina (USSC). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated December 19, 2024.

Round-trip from

$209
(eDestinos)

One-way from

$85
(Mytrip)
From Knoxville McGhee Tyson to South Carolina
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One-way flight from Knoxville McGhee Tyson to South Carolina
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Find flight deals from Knoxville to South Carolina

Cheapest flights from Knoxville to South Carolina
Explore the most affordable flight options available from Knoxville to South Carolina. Find the lowest fares from popular airlines and budget airlines, with prices last updated on December 19, 2024.

This American Airlines deal was found by Cheapflights users on 12/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/242:38 pmTYS - CHS
1 stop3h 42mAmerican Airlines
Tue 12/316:22 pmCHS - TYS
1 stop3h 08mAmerican Airlines
Deal found 12/17$388
This American Airlines deal was found by Cheapflights users on 12/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/267:26 pmTYS - CLT
1 stop35h 14mAmerican Airlines
Sat 12/289:08 amCLT - TYS
Nonstop1h 16mAmerican Airlines
Deal found 12/19$509
This American Airlines deal was found by Cheapflights users on 12/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/252:38 pmTYS - SAV
1 stop4h 57mAmerican Airlines
Sun 12/294:13 pmSAV - TYS
1 stop5h 17mAmerican Airlines
Deal found 12/18$518
This Mytrip deal was found by Cheapflights users on 12/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/266:46 pmTYS - CLT
2 stops15h 42mMultiple Airlines
Fri 1/249:40 pmCLT - TYS
2 stops23h 29mMultiple Airlines
Deal found 12/18$536
This Mytrip deal was found by Cheapflights users on 12/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/284:48 pmTYS - MYR
2 stops17h 43mMultiple Airlines
Mon 12/306:00 amMYR - TYS
2 stops15h 12mMultiple Airlines
Deal found 12/18$539
This American Airlines deal was found by Cheapflights users on 12/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/234:07 pmTYS - CAE
1 stop5h 53mAmerican Airlines
Wed 12/2511:13 amCAE - TYS
1 stop4h 24mAmerican Airlines
Deal found 12/19$543
This Delta deal was found by Cheapflights users on 12/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 12/226:36 pmTYS - CHS
1 stop5h 22mDelta
Wed 12/256:40 amCHS - TYS
1 stop4h 19mDelta
Deal found 12/17$543
This American Airlines deal was found by Cheapflights users on 12/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/237:05 amTYS - MYR
1 stop5h 06mAmerican Airlines
Fri 1/37:03 amMYR - TYS
1 stop2h 56mAmerican Airlines
Deal found 12/17$548
This Delta deal was found by Cheapflights users on 12/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/241:00 pmTYS - CLT
1 stop4h 34mDelta
Fri 12/277:59 pmCLT - TYS
1 stop3h 56mDelta
Deal found 12/18$578
This Delta deal was found by Cheapflights users on 12/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/236:25 amTYS - CAE
1 stop3h 51mDelta
Wed 12/256:29 pmCAE - TYS
1 stop5h 26mDelta
Deal found 12/19$638
This American Airlines deal was found by Cheapflights users on 12/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/197:05 amTYS - HHH
1 stop5h 16mAmerican Airlines
Mon 12/235:59 pmHHH - TYS
1 stop3h 31mAmerican Airlines
Deal found 12/19$668
This Mytrip deal was found by Cheapflights users on 12/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/265:55 pmTYS - CHS
1 stop14h 31mMultiple Airlines
Mon 12/308:51 pmCHS - TYS
2 stops24h 35mMultiple Airlines
Deal found 12/19$684

Find flights from Knoxville to South Carolina within your budget

Customize your flight search to find flights from Knoxville to South Carolina that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated December 19, 2024.

Fly from

Any airport

Fly to

Any airport

Route

Depart

Return

Price

KnoxvilleCharlotte

TYS - CLT

TYSCLT

Knoxville McGhee Tyson

Fri 1/17

9:15 am-12:10 pm

1 stop26h 55m

Charlotte Douglas

Fri 1/24

8:55 pm-4:25 pm

1 stop19h 30m

$209

KnoxvilleMyrtle Beach

TYS - MYR

TYSMYR

Knoxville McGhee Tyson

Sat 1/11

6:11 pm-10:28 pm

1 stop4h 17m

Myrtle Beach Intl

Mon 1/13

6:22 pm-9:27 pm

1 stop3h 05m

$228

KnoxvilleMyrtle Beach

TYS - MYR

TYSMYR

Knoxville McGhee Tyson

Sat 1/11

11:57 am-9:27 pm

2 stops9h 30m

Myrtle Beach Intl

Mon 1/13

6:11 am-2:28 pm

1 stop8h 17m

$244

KnoxvilleCharlotte

TYS - CLT

TYSCLT

Knoxville McGhee Tyson

Wed 1/8

7:17 pm-11:57 am

1 stop16h 40m

Charlotte Douglas

Thu 1/9

1:10 pm-2:18 pm

Nonstop1h 08m

$269

KnoxvilleCharleston

TYS - CHS

TYSCHS

Knoxville McGhee Tyson

Mon 1/6

6:20 am-7:51 pm

1 stop13h 31m

Charleston

Sun 1/12

6:18 pm-2:28 pm

2 stops20h 10m

$337

KnoxvilleCharleston

TYS - CHS

TYSCHS

Knoxville McGhee Tyson

Sat 2/22

12:08 pm-3:44 pm

1 stop3h 36m

Charleston

Mon 2/24

7:05 pm-11:47 pm

1 stop4h 42m

$393

KnoxvilleHilton Head Island

TYS - HHH

TYSHHH

Knoxville McGhee Tyson

Fri 1/17

11:02 am-5:35 pm

1 stop6h 33m

Hilton Head Island

Sun 1/19

6:05 pm-11:58 pm

1 stop5h 53m

$398

KnoxvilleSavannah

TYS - SAV

TYSSAV

Knoxville McGhee Tyson

Fri 1/17

8:05 pm-11:52 pm

1 stop3h 47m

Savannah/Hilton Head

Sun 1/19

8:21 pm-11:58 pm

1 stop3h 37m

$398

KnoxvilleSavannah

TYS - SAV

TYSSAV

Knoxville McGhee Tyson

Sun 1/12

5:45 am-11:07 am

1 stop5h 22m

Savannah/Hilton Head

Sat 1/18

8:26 am-11:23 am

1 stop2h 57m

$403

KnoxvilleCharleston

TYS - CHS

TYSCHS

Knoxville McGhee Tyson

Fri 1/10

2:48 pm-7:35 pm

1 stop4h 47m

Charleston

Fri 1/17

8:25 pm-11:58 pm

1 stop3h 33m

$408

Flights are sorted by cheapest round-trip flights first.

Deals found on 12/19

Showing 1-10 of 32 results
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Best time to book a flight from Knoxville to South Carolina

Have a flexible travel schedule? Discover the best time to fly to South Carolina from Knoxville with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Travel insights for flights from Knoxville to South Carolina

Get recent, data-driven insights about flights from Knoxville to South Carolina including ideal travel times, pricing trends, and more.

What is the cheapest month to book a flight from Knoxville to South Carolina?

Currently, August is the cheapest month in which you can book a flight from Knoxville to South Carolina (average of $217). Flying from Knoxville to South Carolina in March is currently the most expensive (average of $335). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from TYS to SC?

Find hourly flight availability from Knoxville to South Carolina. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated December 19, 2024.

Regardless of the time of day you decide to fly, the ticket price will remain around the same. Book flights from Knoxville to South Carolina as you normally would.

Rainfall in South Carolina by month

Plan your trip to South Carolina by taking into account the average rainfall totals by month.

In terms of precipitation, rainfall in South Carolina ranges from 3.0 - 6.5 inches per month. July is typically the wettest month, when rainfall can reach 6.5 in. November is typically the driest time to visit South Carolina when rainfall is around 3.0 in.

Temperature in South Carolina by month

Plan your trip to South Carolina by taking into account the average temperature totals by month.

If weather is an important factor for your trip to South Carolina, use this chart to help with planning. For those seeking warmer temperatures, July is the ideal time of year to visit, when temperatures reach an average of 78.8 F. Travelers looking to avoid the cold should look outside of January, when temperatures are typically at their lowest (around 44.6 F).

Reviews of airlines servicing South Carolina

Get insights into the airlines that provide service to South Carolina. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to South Carolina. Reviews last updated December 19, 2024.
Get a feel of what it's like to fly with American Airlines, United Airlines and Delta from Knoxville to South Carolina by reading reviews from past customers. You can also see how each airline stacks up in terms of entertainment options, comfort, food, crew/service, and boarding process.
Delta
8.0
Very good
8,600 reviews

Overall

8.0

Food

7.3

Entertainment

7.9

Comfort

8.0

Crew

8.6

Boarding

8.2

Reviews

1 / 10

Delta has consistently been the best U.S. airline for my travels and this flight was no exception

Delta
8.0
Very good
8,600 reviews
Delta
8.0
Very good
8,600 reviews

Overall

8.0

Food

7.3

Entertainment

7.9

Comfort

8.0

Crew

8.6

Boarding

8.2

Reviews

1 / 10

Delta has consistently been the best U.S. airline for my travels and this flight was no exception

United Airlines
7.4
Good
9,048 reviews
Delta
8.0
Very good
8,600 reviews

Overall

8.0

Food

7.3

Entertainment

7.9

Comfort

8.0

Crew

8.6

Boarding

8.2

Reviews

1 / 10

Delta has consistently been the best U.S. airline for my travels and this flight was no exception

Allegiant Air
7.4
Good
829 reviews
Delta
8.0
Very good
8,600 reviews

Overall

8.0

Food

7.3

Entertainment

7.9

Comfort

8.0

Crew

8.6

Boarding

8.2

Reviews

1 / 10

Delta has consistently been the best U.S. airline for my travels and this flight was no exception

American Airlines
7.2
Good
10,000 reviews
Delta
8.0
Very good
8,600 reviews

Overall

8.0

Food

7.3

Entertainment

7.9

Comfort

8.0

Crew

8.6

Boarding

8.2

Reviews

1 / 10

Delta has consistently been the best U.S. airline for my travels and this flight was no exception

Related info for your journey

Find useful and relevant information for your journey from Knoxville to South Carolina. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly from for flights from Knoxville to South Carolina?

    Knoxville McGhee Tyson (TYS) is the airport you will fly out of if you book a flight from Knoxville to South Carolina. It is only a 11.3 mi journey to McGhee Tyson (TYS) from Knoxville’s city center.

  • What are the cheapest airlines to fly from Knoxville to South Carolina one-way?

    $154 is the cheapest one-way deal found within the past few days, from Delta. You may also be able to find cheap deals on American Airlines and Allegiant Air, with prices starting from $185 and $215, respectively.

  • What are the most popular routes from Knoxville to South Carolina?

    The most popular route from Knoxville to South Carolina is Knoxville McGhee Tyson - Savannah/Hilton Head. You may also consider Knoxville McGhee Tyson - Charleston or Knoxville McGhee Tyson - Myrtle Beach Intl.

  • Can I find deals for flights from Knoxville to South Carolina that include hotel bookings?

    Yes. In addition to deals on Knoxville to South Carolina flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Knoxville to South Carolina?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Knoxville to South Carolina.

  • Can I find deals for business class flights from Knoxville to South Carolina?

    Yes. Cheapflights offers flight deals from Knoxville to South Carolina by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Knoxville to South Carolina?

    Currently, August is the cheapest month in which you can book a flight from Knoxville to South Carolina (average of $217). Flying from Knoxville to South Carolina in March is currently the most expensive (average of $335). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

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Alternative routes for Knoxville to South Carolina

See prices for flight routes from nearby airports that may be better suited for you.
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Top 2 airlines flying from Knoxville to South Carolina

Discover the top 2 airlines that operate flights from Knoxville to South Carolina. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated December 19, 2024.
AirlineCheapestAverageFlexibilityOn-time
DeltaCheapest$218Average$388FlexibilityNo cancel feeOn-timeN/A
American AirlinesCheapest$223Average$478FlexibilityNo cancel feeOn-time71%
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