HomeSearch by dateVacation packagesHotelsFlight dealsCar rentalTravel tips & news
South Carolina

$120+ Cheap flights from Knoxville (TYS) to South Carolina

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 12/23. Fares are subject to change and may not be available on all flights or dates of travel.
TYS — CHS
Nov 9 — Nov 161
Sat 11/9
Sat 11/16
1 adult, Economy
We work with more than 300 partners to bring you better travel deals

Find cheap flights from Knoxville to South Carolina with Cheapflights

1. Tell us where you want to go
Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”
2. Select your favorite providers
We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.
3. Compare prices and book
Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.

Find flight deals from Knoxville to South Carolina

Cheapest flights from Knoxville to South Carolina
Explore the most affordable flight options available from Knoxville to South Carolina. Find the lowest fares from popular airlines and budget airlines, with prices last updated on November 4, 2024.

This Mytrip deal was found by Cheapflights users on 11/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/156:00 amTYS - CLT
1 stop14h 50mMultiple Airlines
Sun 11/179:45 pmCLT - TYS
1 stop12h 43mMultiple Airlines
Deal found 11/3$176
This American Airlines deal was found by Cheapflights users on 11/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/28:08 pmTYS - MYR
1 stop3h 50mAmerican Airlines
Sun 12/88:04 pmMYR - TYS
1 stop4h 01mAmerican Airlines
Deal found 11/3$228
This American Airlines deal was found by Cheapflights users on 11/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/297:00 amTYS - CLT
1 stop10h 01mAmerican Airlines
Fri 11/298:19 pmCLT - TYS
Nonstop1h 11mAmerican Airlines
Deal found 11/3$249
This Mytrip deal was found by Cheapflights users on 11/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/166:30 amTYS - MYR
2 stops11h 43mMultiple Airlines
Mon 12/168:44 pmMYR - TYS
1 stop12h 23mMultiple Airlines
Deal found 11/3$275
This Mytrip deal was found by Cheapflights users on 11/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/58:30 amTYS - CHS
2 stops11h 21mMultiple Airlines
Sun 12/88:58 pmCHS - TYS
2 stops20h 20mMultiple Airlines
Deal found 11/3$299
This Mytrip deal was found by Cheapflights users on 11/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/277:10 amTYS - SAV
1 stop14h 20mAllegiant Air
Sat 11/306:00 amSAV - TYS
1 stop8h 52mAllegiant Air
Deal found 11/3$329
This Delta deal was found by Cheapflights users on 11/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/245:30 amTYS - MYR
1 stop5h 05mDelta
Tue 12/36:00 amMYR - TYS
1 stop4h 56mDelta
Deal found 11/4$373
This Delta deal was found by Cheapflights users on 11/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/258:07 amTYS - CLT
1 stop5h 29mDelta
Wed 1/18:26 amCLT - TYS
1 stop5h 26mDelta
Deal found 11/3$378
This American Airlines deal was found by Cheapflights users on 11/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/237:03 amTYS - HHH
1 stop3h 30mAmerican Airlines
Thu 11/2811:11 amHHH - TYS
1 stop3h 15mAmerican Airlines
Deal found 11/4$404
This United deal was found by Cheapflights users on 11/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/107:00 amTYS - CLT
1 stop14h 26mUnited Airlines
Fri 12/135:40 pmCLT - TYS
1 stop23h 25mUnited Airlines
Deal found 11/3$435
This American Airlines deal was found by Cheapflights users on 11/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/145:53 amTYS - CHS
1 stop8h 12mAmerican Airlines
Wed 12/181:52 pmCHS - TYS
1 stop7h 56mAmerican Airlines
Deal found 11/3$437
This Delta deal was found by Cheapflights users on 11/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/34:04 pmTYS - SAV
1 stop4h 58mDelta
Tue 12/1012:17 pmSAV - TYS
1 stop5h 35mDelta
Deal found 11/3$448

Find flights from Knoxville to South Carolina within your budget

Customize your flight search to find flights from Knoxville to South Carolina that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,455,398 searches. Data last updated November 4, 2024.

Fly from

Any airport

Fly to

Any airport

Route

Depart

Return

Price

KnoxvilleCharlotte

TYS - CLT

TYSCLT

Knoxville McGhee Tyson

Mon 12/23

6:20 am-7:37 pm

1 stop13h 17m

$120

KnoxvilleCharlotte

TYS - CLT

TYSCLT

Knoxville McGhee Tyson

Tue 2/4

11:52 am-7:15 pm

1 stop7h 23m

$144

KnoxvilleSavannah

TYS - SAV

TYSSAV

Knoxville McGhee Tyson

Thu 12/19

6:30 am-11:28 pm

2 stops16h 58m

$195

KnoxvilleCharlotte

TYS - CLT

TYSCLT

Knoxville McGhee Tyson

Fri 1/3

7:26 pm-8:25 am

1 stop12h 59m

$214

KnoxvilleCharlotte

TYS - CLT

TYSCLT

Knoxville McGhee Tyson

Sat 2/1

7:00 am-6:58 pm

3 stops11h 58m

$234

KnoxvilleCharleston

TYS - CHS

TYSCHS

Knoxville McGhee Tyson

Sun 1/5

5:53 am-3:33 pm

1 stop9h 40m

$224

KnoxvilleSavannah

TYS - SAV

TYSSAV

Knoxville McGhee Tyson

Fri 11/15

6:00 am-10:33 am

3 stops28h 33m

$225

KnoxvilleCharleston

TYS - CHS

TYSCHS

Knoxville McGhee Tyson

Fri 3/7

5:40 am-10:59 pm

2 stops17h 19m

$289

KnoxvilleCharleston

TYS - CHS

TYSCHS

Knoxville McGhee Tyson

Fri 2/28

11:05 am-3:53 pm

1 stop4h 48m

$275

KnoxvilleSavannah

TYS - SAV

TYSSAV

Knoxville McGhee Tyson

Sun 12/8

6:45 am-12:23 pm

1 stop5h 38m

$279

Flights are sorted by cheapest first

Deals found on 11/3

Showing 1-10 of 36 results
1
2
3
4

Best time to book a flight from Knoxville to South Carolina

Have a flexible travel schedule? Discover the best time to fly to South Carolina from Knoxville with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Travel insights for flights from Knoxville to South Carolina

Get recent, data-driven insights about flights from Knoxville to South Carolina including ideal travel times, pricing trends, and more.

What is the cheapest month to book a flight from Knoxville to South Carolina?

Currently, August is the cheapest month in which you can book a flight from Knoxville to South Carolina (average of $216). Flying from Knoxville to South Carolina in April is currently the most expensive (average of $315). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from TYS to SC?

Find hourly flight availability from Knoxville to South Carolina. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated November 4, 2024.

Regardless of the time of day you decide to fly, the ticket price will remain around the same. Book flights from Knoxville to South Carolina as you normally would.

Rainfall in South Carolina by month

Plan your trip to South Carolina by taking into account the average rainfall totals by month.

In terms of precipitation, rainfall in South Carolina ranges from 3.0 - 6.5 inches per month. July is typically the wettest month, when rainfall can reach 6.5 in. November is typically the driest time to visit South Carolina when rainfall is around 3.0 in.

Temperature in South Carolina by month

Plan your trip to South Carolina by taking into account the average temperature totals by month.

If weather is an important factor for your trip to South Carolina, use this chart to help with planning. For those seeking warmer temperatures, July is the ideal time of year to visit, when temperatures reach an average of 78.8 F. Travelers looking to avoid the cold should look outside of January, when temperatures are typically at their lowest (around 44.6 F).

Reviews of airlines servicing South Carolina

Get insights into the airlines that provide service to South Carolina. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to South Carolina. Reviews last updated November 4, 2024.
Get a feel of what it's like to fly with United Airlines, American Airlines and Delta from Knoxville to South Carolina by reading reviews from past customers. You can also see how each airline stacks up in terms of entertainment options, comfort, food, crew/service, and boarding process.
Delta
8.0
Very good
8,829 reviews

Comfort

7.9

Food

7.3

Boarding

8.2

Entertainment

7.9

Crew

8.5

Overall

8.0

Reviews

1 / 10

Delta has consistently been the best U.S. airline for my travels and this flight was no exception

Delta
8.0
Very good
8,829 reviews
Delta
8.0
Very good
8,829 reviews

Comfort

7.9

Food

7.3

Boarding

8.2

Entertainment

7.9

Crew

8.5

Overall

8.0

Reviews

1 / 10

Delta has consistently been the best U.S. airline for my travels and this flight was no exception

United Airlines
7.4
Good
9,226 reviews
Delta
8.0
Very good
8,829 reviews

Comfort

7.9

Food

7.3

Boarding

8.2

Entertainment

7.9

Crew

8.5

Overall

8.0

Reviews

1 / 10

Delta has consistently been the best U.S. airline for my travels and this flight was no exception

Allegiant Air
7.4
Good
865 reviews
Delta
8.0
Very good
8,829 reviews

Comfort

7.9

Food

7.3

Boarding

8.2

Entertainment

7.9

Crew

8.5

Overall

8.0

Reviews

1 / 10

Delta has consistently been the best U.S. airline for my travels and this flight was no exception

American Airlines
7.2
Good
10,000 reviews
Delta
8.0
Very good
8,829 reviews

Comfort

7.9

Food

7.3

Boarding

8.2

Entertainment

7.9

Crew

8.5

Overall

8.0

Reviews

1 / 10

Delta has consistently been the best U.S. airline for my travels and this flight was no exception

Related info for your journey

Find useful and relevant information for your journey from Knoxville to South Carolina. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly from for flights from Knoxville to South Carolina?

    Knoxville McGhee Tyson (TYS) is the airport you will fly out of if you book a flight from Knoxville to South Carolina. It is only a 11.3 mi journey to McGhee Tyson (TYS) from Knoxville’s city center.

  • Can I find flights from Knoxville to South Carolina for under $200 on Cheapflights?

    Yes, there are multiple flights from Knoxville to South Carolina for under $200. The cheapest flight booked recently is on Multiple Airlines for just $176, but on average you can expect to pay $401.

  • Are there nonstop flights from Knoxville to South Carolina for under $400 on Cheapflights?

    Cheapflights has at least 1 direct flight from Knoxville to South Carolina under $400. A good price for a nonstop flight from Knoxville to South Carolina is less than $359.

  • Are there last-minute flights available from Knoxville to South Carolina for under $200?

    There are currently 10+ open flights from Knoxville to South Carolina within the next 7 days for less than $200.

  • What are the cheapest airlines to fly from Knoxville to South Carolina one-way?

    $144 is the cheapest one-way deal found within the past few days, from Delta. You may also be able to find cheap deals on Allegiant Air and American Airlines, with prices starting from $195 and $214, respectively.

  • What are the most popular routes from Knoxville to South Carolina?

    The most popular route from Knoxville to South Carolina is Knoxville McGhee Tyson - Savannah/Hilton Head. You may also consider Knoxville McGhee Tyson - Charlotte Douglas or Knoxville McGhee Tyson - Charleston.

  • What does TYS to CHS mean?

    Knoxville McGhee Tyson Airport is TYS and Charleston Airport is CHS. These codes are created by the International Air Transport Association (IATA) and airlines use them to identify the departing and arrival airports in the flight routes they service. While you’re still figuring out your travel plans, it’s not a bad idea to learn the names and codes of other airports around these areas: Myrtle Beach Intl Airport (MYR), Greenville Airport (GSP), Columbia Metropolitan Airport (CAE), Hilton Head Island Airport (HHH), Florence Airport (FLO).

  • Can I find deals for flights from Knoxville to South Carolina that include extra baggage allowance?

    The amount of baggage you can bring on your Knoxville to South Carolina flight depends on the airline and the type of fare you've chosen. After entering your flight details, you'll be able to view the specific baggage policies for each deal in the search results. Keep in mind that certain deals may offer additional baggage allowance.

  • Can I find deals on flights from Knoxville to South Carolina with specific airlines?

    Yes, Cheapflights allows you to browse and filter Knoxville to South Carolina flight deals by airline. After entering your origin and destination, use the available filters to view flights offered by airlines.

  • Can I find deals for flights from Knoxville to South Carolina that include hotel bookings?

    Yes. In addition to deals on Knoxville to South Carolina flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Knoxville to South Carolina?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Knoxville to South Carolina.

  • Can I find deals for business class flights from Knoxville to South Carolina?

    Yes. Cheapflights offers flight deals from Knoxville to South Carolina by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • Can I find deals for flights from Knoxville to South Carolina that allow pets onboard?

    Many airlines flying from Knoxville to South Carolina offer the option to travel with pets. After selecting a flight deal, you can find more information about the airline's pet policy on their official website or by contacting the airline directly. Please note that additional fees and restrictions may apply.

  • Can I find deals on last-minute flights from Knoxville to South Carolina?

    Yes, you can often find last-minute deals on Knoxville to South Carolina flights on Cheapflights. However, these deals can vary and may not always be available. We recommend checking back frequently or signing up for price alerts for the most up-to-date deals.

  • How recently were the Knoxville to South Carolina flight deals updated?

    The Knoxville to South Carolina flight deals you see on this page were last updated on 11/4.

  • What is the cheapest month to book a flight from Knoxville to South Carolina?

    Currently, August is the cheapest month in which you can book a flight from Knoxville to South Carolina (average of $216). Flying from Knoxville to South Carolina in April is currently the most expensive (average of $315). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Browse thousands of different options on Cheapflights for your next trip

Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.

Alternative routes for Knoxville to South Carolina

See prices for flight routes from nearby airports that may be better suited for you.
Nashville to LaGuardia flights
Nashville to John F Kennedy Intl flights
Nashville to Newark flights
Nashville to Las Vegas flights
Chattanooga to LaGuardia flights
Nashville to Dallas/Fort Worth flights
Nashville to Los Angeles flights
Nashville to O'Hare Intl flights
Nashville to Orlando flights
Nashville to Fort Lauderdale flights
Chattanooga to John F Kennedy Intl flights
Nashville to Seattle flights
Memphis to LaGuardia flights
Nashville to Miami flights
Nashville to Denver flights
Memphis to Las Vegas flights
Nashville to Boston flights
Nashville to San Francisco flights
Memphis to Newark flights
Memphis to Los Angeles flights
Memphis to John F Kennedy Intl flights
Nashville to Sky Harbor Intl flights
Nashville to Dulles Intl flights
Nashville to Hobby flights
Memphis to O'Hare Intl flights
Memphis to Miami flights
Memphis to Dallas/Fort Worth flights
Nashville to Salt Lake City flights
Memphis to Orlando flights
Chattanooga to Newark flights
Knoxville to LaGuardia flights
Memphis to Denver flights
Memphis to Atlanta flights
Nashville to Reagan-National flights
Nashville to Baltimore flights
Memphis to Hobby flights
Nashville to Tampa flights
Knoxville to John F Kennedy Intl flights
Nashville to George Bush Intcntl flights
Nashville to Austin flights
Nashville to Charlotte flights
Nashville to Ontario flights
Nashville to Love Field flights
Knoxville to Denver flights
Memphis to George Bush Intcntl flights
Knoxville to Dulles Intl flights
Knoxville to Hobby flights
Nashville to Raleigh flights
Nashville to Honolulu flights
Chattanooga to Orlando flights

Top 2 airlines flying from Knoxville to South Carolina

Discover the top 2 airlines that operate flights from Knoxville to South Carolina. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,455,398 searches. Data last updated November 4, 2024.
AirlineCheapestAverageFlexibilityOn-time
American AirlinesCheapest$204Average$488FlexibilityNo cancel feeOn-time71%
DeltaCheapest$208Average$380FlexibilityNo cancel feeOn-timeN/A
100% Free
Cheapflights is completely free to use, so you can start saving the moment you arrive.
Book with Flexibility
Our users can plan ahead with confidence and find flights with no change fees
Travel Smart
Millions of people come to us for their flight needs every year. We help make travel planning easy by providing useful insights and data-driven graphs that can inform your decisions.
View all available airlines