HomeSearch by dateVacation packagesHotelsFlight dealsCar rentalTravel tips & news
South Carolina

$306+ Cheap flights from Italy to South Carolina

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 5/20. Fares are subject to change and may not be available on all flights or dates of travel.
NAP — CHS
Apr 27 — May 41
Sun 4/27
Sun 5/4
1 adult, Economy
We work with more than 300 partners to bring you better travel deals

Find cheap flights from Italy to South Carolina with Cheapflights

1. Tell us where you want to go

Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”

2. Select your favorite providers

We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.

3. Compare prices and book

Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.

Cheap flight deals from Italy to South Carolina

Keep the following information in mind while searching for Italy to South Carolina flight deals. Data was last updated April 22, 2025.

Round-trip from

$568
(Mytrip)

One-way from

$306
(Kiwi.com)
From Italy to South Carolina
Search Deals
One-way flight from Italy to South Carolina
Search Deals

Find flight deals from Italy to South Carolina

Cheapest flights from Italy to South Carolina
Explore the most affordable flight options available from Italy to South Carolina. Find the lowest fares from popular airlines and budget airlines, with prices last updated on April 22, 2025.

This Mytrip deal was found by Cheapflights users on 4/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 5/57:05 pmFCO - CLT
1 stop18h 41mMultiple Airlines
Mon 5/125:45 amCLT - FCO
1 stop26h 45mMultiple Airlines
Deal found 4/21$568
This lol.travel deal was found by Cheapflights users on 4/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure lol.travel is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 5/1912:10 pmFCO - CLT
Nonstop10h 30mIberia
Tue 6/36:30 pmCLT - FCO
Nonstop9h 20mIberia
Deal found 4/21$645
This American Airlines deal was found by Cheapflights users on 4/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 4/2811:10 amMXP - CLT
1 stop12h 20mAmerican Airlines
Mon 5/56:35 pmCLT - MXP
1 stop20h 10mAmerican Airlines
Deal found 4/21$649
This American Airlines deal was found by Cheapflights users on 4/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/27:50 amNAP - CLT
1 stop17h 00mAmerican Airlines
Fri 5/911:30 pmCLT - NAP
1 stop16h 30mAmerican Airlines
Deal found 4/22$652
This lol.travel deal was found by Cheapflights users on 4/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure lol.travel is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/72:30 pmFCO - CHS
1 stop31h 41mAir Canada
Sun 5/114:55 pmCHS - FCO
2 stops34h 20mAir Canada
Deal found 4/21$655
This Booking.com deal was found by Cheapflights users on 4/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Booking.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 5/511:10 amMXP - CLT
1 stop12h 20mBritish Airways
Mon 5/1211:30 pmCLT - MXP
1 stop18h 10mBritish Airways
Deal found 4/21$656
This American Airlines deal was found by Cheapflights users on 4/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/27:25 amLIN - CLT
1 stop17h 25mAmerican Airlines
Fri 5/911:30 pmCLT - LIN
1 stop16h 10mAmerican Airlines
Deal found 4/22$657
This United Airlines deal was found by Cheapflights users on 4/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/47:05 amFCO - CLT
2 stops15h 14mUnited Airlines
Tue 11/116:30 amCLT - FCO
1 stop19h 15mUnited Airlines
Deal found 4/21$658
This British Airways deal was found by Cheapflights users on 4/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure British Airways is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 5/57:25 amLIN - CLT
1 stop17h 30mBritish Airways
Mon 5/1211:30 pmCLT - LIN
1 stop13h 25mBritish Airways
Deal found 4/21$658
This Booking.com deal was found by Cheapflights users on 4/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Booking.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 5/512:10 pmFCO - CLT
Nonstop10h 30mBritish Airways
Mon 5/1211:30 pmCLT - FCO
1 stop13h 45mBritish Airways
Deal found 4/21$660
This Delta deal was found by Cheapflights users on 4/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 5/59:00 amMXP - CLT
2 stops20h 46mDelta
Mon 5/125:05 pmCLT - MXP
2 stops14h 50mDelta
Deal found 4/21$662
This Delta deal was found by Cheapflights users on 4/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/2011:40 amMXP - GSP
1 stop16h 03mDelta
Tue 5/276:33 pmGSP - MXP
2 stops13h 22mDelta
Deal found 4/22$662

Cheapflights Fare Finder

Customize your flight search to find flights from Italy to South Carolina that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated April 22, 2025.
Use the filters below to find and compare flights from Italy to South Carolina that are best for you.

Fly from

Italy

Fly to

South Carolina

Route

Depart

Return

Price

RomeCharlotte

FCO - CLT

FCOCLT

Rome Fiumicino

Mon 5/5

7:05 pm-7:46 am

1 stop18h 41m

Charlotte Douglas

Mon 5/12

5:45 am-2:30 pm

1 stop26h 45m

$568

RomeCharlotte

FCO - CLT

FCOCLT

Rome Fiumicino

Mon 5/19

12:10 pm-4:40 pm

Nonstop10h 30m

Charlotte Douglas

Tue 6/3

6:30 pm-9:50 am

Nonstop9h 20m

$645

NaplesCharlotte

NAP - CLT

NAPCLT

Naples

Fri 5/2

7:50 am-6:50 pm

1 stop17h 00m

Charlotte Douglas

Fri 5/9

11:30 pm-10:00 pm

1 stop16h 30m

$652

MilanCharlotte

MXP - CLT

MXPCLT

Milan Malpensa

Fri 5/2

11:10 am-5:30 pm

1 stop12h 20m

Charlotte Douglas

Fri 5/9

11:30 pm-11:00 pm

1 stop17h 30m

$654

RomeCharleston

FCO - CHS

FCOCHS

Rome Fiumicino

Wed 5/7

11:30 am-4:11 pm

2 stops34h 41m

Charleston

Sun 5/11

4:55 pm-9:15 am

2 stops34h 20m

$655

MilanCharlotte

LIN - CLT

LINCLT

Milan Linate

Fri 5/2

7:25 am-6:50 pm

1 stop17h 25m

Charlotte Douglas

Fri 5/9

11:30 pm-9:40 pm

1 stop16h 10m

$657

MilanCharlotte

LIN - CLT

LINCLT

Milan Linate

Mon 5/5

7:25 am-6:55 pm

1 stop17h 30m

Charlotte Douglas

Mon 5/12

11:30 pm-6:55 pm

1 stop13h 25m

$658

RomeCharlotte

FCO - CLT

FCOCLT

Rome Fiumicino

Mon 5/5

12:10 pm-4:40 pm

Nonstop10h 30m

Charlotte Douglas

Mon 5/12

11:30 pm-7:15 pm

1 stop13h 45m

$660

MilanCharlotte

MXP - CLT

MXPCLT

Milan Malpensa

Mon 5/5

9:00 am-11:46 pm

2 stops20h 46m

Charlotte Douglas

Mon 5/12

5:05 pm-1:55 pm

2 stops14h 50m

$662

MilanGreenville

MXP - GSP

MXPGSP

Milan Malpensa

Tue 5/20

11:40 am-9:43 pm

1 stop16h 03m

Greenville

Tue 5/27

6:33 pm-1:55 pm

2 stops13h 22m

$662

Flights are sorted by cheapest round-trip flights first.

Deals found on 4/22

Showing 1-10 of 60 results
1
2
3
...
6

Best time to book a flight from Italy to South Carolina

Have a flexible travel schedule? Discover the best time to fly to South Carolina from Italy with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Italy to South Carolina

What is the cheapest time of day to fly from IT to SC?

Find hourly flight availability from Italy to South Carolina. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated April 22, 2025.

Regardless of the time of day you decide to fly, the ticket price will remain around the same. Book flights from Italy to South Carolina as you normally would.

Rainfall in South Carolina by month

Plan your trip to South Carolina by taking into account the average rainfall totals by month.

In terms of precipitation, rainfall in South Carolina ranges from 3.0 - 6.5 inches per month. July is typically the wettest month, when rainfall can reach 6.5 in. November is typically the driest time to visit South Carolina when rainfall is around 3.0 in.

Temperature in South Carolina by month

Plan your trip to South Carolina by taking into account the average temperature totals by month.

If weather is an important factor for your trip to South Carolina, use this chart to help with planning. For those seeking warmer temperatures, July is the ideal time of year to visit, when temperatures reach an average of 78.8 F. Travelers looking to avoid the cold should look outside of January, when temperatures are typically at their lowest (around 44.6 F).

Reviews of airlines servicing South Carolina

Get insights into the airlines that provide service to South Carolina. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to South Carolina. Reviews last updated April 22, 2025.
Peruse reviews from past customers who have flown with Emirates, Delta and KLM from Italy to South Carolina to help guide your decision. You can also see how each airline stacks up in terms of entertainment options, comfort, food, crew/service, and boarding process.
Emirates
8.0
Very good
3,205 reviews

Food

7.8

Boarding

8.1

Comfort

8.0

Crew

8.3

Entertainment

8.2

Overall

8.0

Reviews

1 / 20
2.0
Mediocre

Anonymous,Jun 2024

DXB - IAH

It was not a good experience the seats were small and uncomfortable the food was not good and they forgot to serve me my breakfast - there were 5 us in 2 rows that they just completely skipped us. Very disappointed.
Emirates
8.0
Very good
3,205 reviews
Emirates
8.0
Very good
3,205 reviews

Food

7.8

Boarding

8.1

Comfort

8.0

Crew

8.3

Entertainment

8.2

Overall

8.0

Reviews

1 / 20
2.0
Mediocre

Anonymous,Jun 2024

DXB - IAH

It was not a good experience the seats were small and uncomfortable the food was not good and they forgot to serve me my breakfast - there were 5 us in 2 rows that they just completely skipped us. Very disappointed.
Delta
8.0
Very good
7,920 reviews
Emirates
8.0
Very good
3,205 reviews

Food

7.8

Boarding

8.1

Comfort

8.0

Crew

8.3

Entertainment

8.2

Overall

8.0

Reviews

1 / 20
2.0
Mediocre

Anonymous,Jun 2024

DXB - IAH

It was not a good experience the seats were small and uncomfortable the food was not good and they forgot to serve me my breakfast - there were 5 us in 2 rows that they just completely skipped us. Very disappointed.
KLM
7.8
Good
1,331 reviews
Emirates
8.0
Very good
3,205 reviews

Food

7.8

Boarding

8.1

Comfort

8.0

Crew

8.3

Entertainment

8.2

Overall

8.0

Reviews

1 / 20
2.0
Mediocre

Anonymous,Jun 2024

DXB - IAH

It was not a good experience the seats were small and uncomfortable the food was not good and they forgot to serve me my breakfast - there were 5 us in 2 rows that they just completely skipped us. Very disappointed.
Finnair
7.6
Good
1,272 reviews
Emirates
8.0
Very good
3,205 reviews

Food

7.8

Boarding

8.1

Comfort

8.0

Crew

8.3

Entertainment

8.2

Overall

8.0

Reviews

1 / 20
2.0
Mediocre

Anonymous,Jun 2024

DXB - IAH

It was not a good experience the seats were small and uncomfortable the food was not good and they forgot to serve me my breakfast - there were 5 us in 2 rows that they just completely skipped us. Very disappointed.
SWISS
7.5
Good
1,582 reviews
Emirates
8.0
Very good
3,205 reviews

Food

7.8

Boarding

8.1

Comfort

8.0

Crew

8.3

Entertainment

8.2

Overall

8.0

Reviews

1 / 20
2.0
Mediocre

Anonymous,Jun 2024

DXB - IAH

It was not a good experience the seats were small and uncomfortable the food was not good and they forgot to serve me my breakfast - there were 5 us in 2 rows that they just completely skipped us. Very disappointed.

Related info for your journey

Find useful and relevant information for your journey from Italy to South Carolina. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What are the cheapest airlines to fly from Italy to South Carolina one-way?

    To fly one-way, consider booking your trip with Aer Lingus, which is currently one of the cheapest options available, starting at $508. WestJet flights start at $563 while deals on Turkish Airlines start at $593 one-way.

  • Can I find deals for flights from Italy to South Carolina that include hotel bookings?

    Yes. In addition to deals on Italy to South Carolina flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Italy to South Carolina?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Italy to South Carolina.

  • Can I find deals for business class flights from Italy to South Carolina?

    Yes. Cheapflights offers flight deals from Italy to South Carolina by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Italy to South Carolina?

    Currently, August is the cheapest month in which you can book a flight from Italy to South Carolina (average of $217). Flying from Italy to South Carolina in March is currently the most expensive (average of $335). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Browse thousands of different options on Cheapflights for your next trip

Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.

Alternative routes for Italy to South Carolina

See prices for flight routes from nearby airports that may be better suited for you.
Charles de Gaulle to John F Kennedy Intl flights
Charles de Gaulle to Newark flights
Heathrow to John F Kennedy Intl flights
Heathrow to Newark flights
Orly to John F Kennedy Intl flights
Charles de Gaulle to LaGuardia flights
Orly to Newark flights
Frankfurt to John F Kennedy Intl flights
Gatwick to John F Kennedy Intl flights
Charles de Gaulle to Miami flights
Frankfurt to Newark flights
Madrid to John F Kennedy Intl flights
Frankfurt to LaGuardia flights
Charles de Gaulle to Stewart flights
Heathrow to LaGuardia flights
Madrid to Newark flights
Bruxelles-National to John F Kennedy Intl flights
Malpensa to Newark flights
Madrid to Miami flights
Gatwick to Newark flights
London City to John F Kennedy Intl flights
Malpensa to John F Kennedy Intl flights
Zurich to John F Kennedy Intl flights
Frederic Chopin to John F Kennedy Intl flights
Barcelona-El Prat to Newark flights
Leonardo da Vinci/Fiumicino to John F Kennedy Intl flights
London City to Newark flights
Vienna to Newark flights
Leonardo da Vinci/Fiumicino to Newark flights
Bruxelles-National to Newark flights
Frankfurt to Los Angeles flights
Gatwick to LaGuardia flights
Dublin to John F Kennedy Intl flights
Vienna to John F Kennedy Intl flights
Zurich to Newark flights
Frederic Chopin to Newark flights
Munich to John F Kennedy Intl flights
Berlin to John F Kennedy Intl flights
Vicenza to John F Kennedy Intl flights
Heathrow to Los Angeles flights
Charles de Gaulle to Los Angeles flights
Vicenza to Newark flights
Charles de Gaulle to San Francisco flights
Amsterdam to Newark flights
Dublin to Newark flights
Heathrow to Boston flights
Amsterdam to John F Kennedy Intl flights
Barcelona-El Prat to John F Kennedy Intl flights

Top airline flying from Italy to South Carolina

Discover the top airline that operate flights from Italy to South Carolina. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated April 22, 2025.
AirlineCheapestAverageFlexibilityOn-time
United AirlinesCheapest$634Average$690FlexibilityNo cancel feeOn-time69%

100% Free

Cheapflights is completely free to use, so you can start saving the moment you arrive.

Book with Flexibility

Our users can plan ahead with confidence and find flights with no change fees

Travel Smart

Millions of people come to us for their flight needs every year. We help make travel planning easy by providing useful insights and data-driven graphs that can inform your decisions.