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South Carolina

$136+ Cheap flights from Iowa to South Carolina

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 5/28. Fares are subject to change and may not be available on all flights or dates of travel.
DSM — CHS
Apr 6 — Apr 131
Sun 4/6
Sun 4/13
1 adult, Economy
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Cheap flight deals from Iowa to South Carolina

Keep the following information in mind while searching for Iowa to South Carolina flight deals. Data was last updated April 1, 2025.

Most accurate provider

FlightHub
3 stars

Most trusted provider

FlightHub
3 stars

Round-trip from

$199
(American Airlines)

One-way from

$136
(American Airlines)

Popular in

December

Cheapest in

September

Average price

$353
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From Iowa to South Carolina
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One-way flight from Iowa to South Carolina
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Highest demand for flights based on searches. 8% potential increase in price ($33 potential increase over avg. RT price).
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Cheapest flight prices on average. 2% potential price decrease ($11 potential savings vs. average RT price).
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Average for round-trip flights in April 2025
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Find flight deals from Iowa to South Carolina

Cheapest flights from Iowa to South Carolina
Explore the most affordable flight options available from Iowa to South Carolina. Find the lowest fares from popular airlines and budget airlines, with prices last updated on April 1, 2025.

This American Airlines deal was found by Cheapflights users on 3/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/36:00 amCID - CHS
1 stop7h 06mAmerican Airlines
Tue 5/63:42 pmCHS - CID
1 stop8h 26mAmerican Airlines
Deal found 3/31$199
This Mytrip deal was found by Cheapflights users on 3/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 5/125:47 pmCID - CLT
1 stop27h 13mMultiple Airlines
Thu 5/159:02 pmCLT - CID
1 stop22h 06mMultiple Airlines
Deal found 3/31$208
This Mytrip deal was found by Cheapflights users on 3/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 4/283:25 pmDSM - CHS
1 stop16h 55mMultiple Airlines
Mon 5/510:32 amCHS - DSM
1 stop12h 26mMultiple Airlines
Deal found 3/31$212
This Mytrip deal was found by Cheapflights users on 3/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 5/1812:32 pmDSM - CLT
1 stop26h 05mMultiple Airlines
Thu 5/2211:52 amCLT - DSM
1 stop27h 58mMultiple Airlines
Deal found 3/31$217
This Mytrip deal was found by Cheapflights users on 3/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 4/255:47 pmCID - CHS
1 stop15h 25mMultiple Airlines
Mon 4/2810:32 amCHS - CID
1 stop7h 25mMultiple Airlines
Deal found 3/31$219
This Mytrip deal was found by Cheapflights users on 3/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 4/283:25 pmDSM - SAV
1 stop6h 48mAllegiant Air
Mon 5/512:34 pmSAV - DSM
1 stop10h 24mAllegiant Air
Deal found 3/31$238
This CheapOair deal was found by Cheapflights users on 3/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 4/118:17 pmDSM - CLT
1 stop21h 40mFrontier
Sun 4/1310:20 pmCLT - DSM
1 stop21h 59mFrontier
Deal found 3/31$240
This Delta deal was found by Cheapflights users on 3/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 4/155:30 amCID - CHS
1 stop4h 57mDelta
Sat 4/196:41 pmCHS - CID
1 stop4h 38mDelta
Deal found 3/31$258
This Mytrip deal was found by Cheapflights users on 3/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/178:26 pmCID - CLT
1 stop21h 22mFrontier
Mon 4/217:47 pmCLT - CID
1 stop24h 27mFrontier
Deal found 3/31$267
This American Airlines deal was found by Cheapflights users on 4/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 4/295:00 amDSM - GSP
1 stop5h 37mAmerican Airlines
Tue 5/66:36 pmGSP - DSM
1 stop6h 22mAmerican Airlines
Deal found 4/1$270
This American Airlines deal was found by Cheapflights users on 3/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/231:59 pmDSM - CHS
1 stop4h 29mAmerican Airlines
Tue 4/296:28 amCHS - DSM
1 stop6h 27mAmerican Airlines
Deal found 3/31$271
This Delta deal was found by Cheapflights users on 3/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/2310:22 amDSM - GSP
1 stop6h 12mDelta
Wed 4/305:46 amGSP - DSM
1 stop5h 55mDelta
Deal found 3/31$271

Cheapflights Fare Finder

Customize your flight search to find flights from Iowa to South Carolina that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated April 1, 2025.
Use the filters below to find and compare flights from Iowa to South Carolina that are best for you.

Fly from

Iowa

Fly to

South Carolina

Route

Depart

Return

Price

Cedar RapidsCharleston

CID - CHS

CIDCHS

Cedar Rapids

Sat 5/3

6:00 am-2:06 pm

1 stop7h 06m

Charleston

Tue 5/6

3:42 pm-11:08 pm

1 stop8h 26m

$199

Cedar RapidsCharlotte

CID - CLT

CIDCLT

Cedar Rapids

Mon 5/12

5:47 pm-10:00 pm

1 stop27h 13m

Charlotte Douglas

Thu 5/15

9:02 pm-6:08 pm

1 stop22h 06m

$208

Des MoinesCharleston

DSM - CHS

DSMCHS

Des Moines

Mon 4/28

3:25 pm-9:20 am

1 stop16h 55m

Charleston

Mon 5/5

10:32 am-9:58 pm

1 stop12h 26m

$212

Des MoinesCharlotte

DSM - CLT

DSMCLT

Des Moines

Sun 5/18

12:32 pm-3:37 pm

1 stop26h 05m

Charlotte Douglas

Thu 5/22

11:52 am-2:50 pm

1 stop27h 58m

$217

Cedar RapidsCharleston

CID - CHS

CIDCHS

Cedar Rapids

Fri 4/25

5:47 pm-10:12 am

1 stop15h 25m

Charleston

Mon 4/28

10:32 am-4:57 pm

1 stop7h 25m

$219

Des MoinesSavannah

DSM - SAV

DSMSAV

Des Moines

Mon 4/28

3:25 pm-11:13 pm

1 stop6h 48m

Savannah/Hilton Head

Mon 5/5

12:34 pm-9:58 pm

1 stop10h 24m

$238

Des MoinesCharlotte

DSM - CLT

DSMCLT

Des Moines

Fri 4/11

8:17 pm-6:57 pm

1 stop21h 40m

Charlotte Douglas

Sun 4/13

10:20 pm-7:19 pm

1 stop21h 59m

$240

Cedar RapidsCharleston

CID - CHS

CIDCHS

Cedar Rapids

Tue 4/15

5:30 am-11:27 am

1 stop4h 57m

Charleston

Sat 4/19

6:41 pm-10:19 pm

1 stop4h 38m

$258

Cedar RapidsCharlotte

CID - CLT

CIDCLT

Cedar Rapids

Thu 4/17

8:26 pm-6:48 pm

1 stop21h 22m

Charlotte Douglas

Mon 4/21

7:47 pm-7:14 pm

1 stop24h 27m

$267

Des MoinesGreenville

DSM - GSP

DSMGSP

Des Moines

Tue 4/29

5:00 am-11:37 am

1 stop5h 37m

Greenville

Tue 5/6

6:36 pm-11:58 pm

1 stop6h 22m

$270

Flights are sorted by cheapest round-trip flights first.

Deals found on 4/1

Showing 1-10 of 57 results
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Best time to book a flight from Iowa to South Carolina

Have a flexible travel schedule? Discover the best time to fly to South Carolina from Iowa with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Iowa to South Carolina

What is the cheapest month to book a flight from Iowa to South Carolina?

Currently, August is the cheapest month in which you can book a flight from Iowa to South Carolina (average of $217). Flying from Iowa to South Carolina in March is currently the most expensive (average of $335). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from IA to SC?

Find hourly flight availability from Iowa to South Carolina. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated April 1, 2025.

When flying from Iowa to South Carolina, the time of day you decide to fly out makes little to no difference towards the overall price you’ll pay on tickets.

Rainfall in South Carolina by month

Plan your trip to South Carolina by taking into account the average rainfall totals by month.

In terms of precipitation, rainfall in South Carolina ranges from 3.0 - 6.5 inches per month. July is typically the wettest month, when rainfall can reach 6.5 in. November is typically the driest time to visit South Carolina when rainfall is around 3.0 in.

Temperature in South Carolina by month

Plan your trip to South Carolina by taking into account the average temperature totals by month.

If weather is an important factor for your trip to South Carolina, use this chart to help with planning. For those seeking warmer temperatures, July is the ideal time of year to visit, when temperatures reach an average of 78.8 F. Travelers looking to avoid the cold should look outside of January, when temperatures are typically at their lowest (around 44.6 F).

Reviews of airlines servicing South Carolina

Get insights into the airlines that provide service to South Carolina. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to South Carolina. Reviews last updated April 1, 2025.
Read through reviews of airlines operating flights from Iowa to South Carolina, such as Alaska Airlines, Southwest and Delta. Users have also rated airlines in terms of entertainment options, comfort, food, crew/service, and boarding process.
Alaska Airlines
8.0
Very good
9,818 reviews

Crew

8.5

Comfort

7.9

Boarding

8.2

Entertainment

7.1

Overall

8.0

Food

7.1

Reviews

1 / 20
10.0
Excellent

Cheri,Jan 2025

FAT - SEA

Very friendly. I really liked that they had water for us in cartons not plastic. Impressed with Alaska Airlines, First time I had flown them
Alaska Airlines
8.0
Very good
9,818 reviews
Alaska Airlines
8.0
Very good
9,818 reviews

Crew

8.5

Comfort

7.9

Boarding

8.2

Entertainment

7.1

Overall

8.0

Food

7.1

Reviews

1 / 20
10.0
Excellent

Cheri,Jan 2025

FAT - SEA

Very friendly. I really liked that they had water for us in cartons not plastic. Impressed with Alaska Airlines, First time I had flown them
Southwest
8.0
Very good
4,277 reviews
Alaska Airlines
8.0
Very good
9,818 reviews

Crew

8.5

Comfort

7.9

Boarding

8.2

Entertainment

7.1

Overall

8.0

Food

7.1

Reviews

1 / 20
10.0
Excellent

Cheri,Jan 2025

FAT - SEA

Very friendly. I really liked that they had water for us in cartons not plastic. Impressed with Alaska Airlines, First time I had flown them
Delta
8.0
Very good
7,899 reviews
Alaska Airlines
8.0
Very good
9,818 reviews

Crew

8.5

Comfort

7.9

Boarding

8.2

Entertainment

7.1

Overall

8.0

Food

7.1

Reviews

1 / 20
10.0
Excellent

Cheri,Jan 2025

FAT - SEA

Very friendly. I really liked that they had water for us in cartons not plastic. Impressed with Alaska Airlines, First time I had flown them
United Airlines
7.4
Good
8,615 reviews
Alaska Airlines
8.0
Very good
9,818 reviews

Crew

8.5

Comfort

7.9

Boarding

8.2

Entertainment

7.1

Overall

8.0

Food

7.1

Reviews

1 / 20
10.0
Excellent

Cheri,Jan 2025

FAT - SEA

Very friendly. I really liked that they had water for us in cartons not plastic. Impressed with Alaska Airlines, First time I had flown them
Allegiant Air
7.3
Good
731 reviews
Alaska Airlines
8.0
Very good
9,818 reviews

Crew

8.5

Comfort

7.9

Boarding

8.2

Entertainment

7.1

Overall

8.0

Food

7.1

Reviews

1 / 20
10.0
Excellent

Cheri,Jan 2025

FAT - SEA

Very friendly. I really liked that they had water for us in cartons not plastic. Impressed with Alaska Airlines, First time I had flown them

Related info for your journey

Find useful and relevant information for your journey from Iowa to South Carolina. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What are the cheapest airlines to fly from Iowa to South Carolina one-way?

    The cheapest airline one-way is American Airlines, with whom users have recently found tickets for as low as $136. However, be on the lookout for offers from Frontier and Delta, as they are both options that can get you from Iowa to South Carolina for a low price.

  • Can I find deals for flights from Iowa to South Carolina that include hotel bookings?

    Yes. In addition to deals on Iowa to South Carolina flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Iowa to South Carolina?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Iowa to South Carolina.

  • Can I find deals for business class flights from Iowa to South Carolina?

    Yes. Cheapflights offers flight deals from Iowa to South Carolina by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Iowa to South Carolina?

    Currently, August is the cheapest month in which you can book a flight from Iowa to South Carolina (average of $217). Flying from Iowa to South Carolina in March is currently the most expensive (average of $335). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Browse thousands of different options on Cheapflights for your next trip

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Alternative routes for Iowa to South Carolina

See prices for flight routes from nearby airports that may be better suited for you.
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Top 3 airlines flying from Iowa to South Carolina

Discover the top 3 airlines that operate flights from Iowa to South Carolina. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated April 1, 2025.
AirlineCheapestAverageFlexibilityOn-time
American AirlinesCheapest$214Average$383FlexibilityNo cancel feeOn-time71%
United AirlinesCheapest$227Average$415FlexibilityNo cancel feeOn-time69%
DeltaCheapest$232Average$359FlexibilityNo cancel feeOn-timeN/A
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