South Carolina

$63+ Cheap flights from Iowa to South Carolina

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 1/9. Fares are subject to change and may not be available on all flights or dates of travel.
DSM — CHS
Dec 27 — Jan 31
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Cheap flight deals from Iowa to South Carolina

Discover tips and strategies to find the most affordable flight options for your journey from Iowa (USIA) to South Carolina (USSC). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated December 22, 2024.

Round-trip from

$197
(FlightHub)

One-way from

$63
(Mytrip)
From Iowa to South Carolina
One-way flight from Iowa to South Carolina

Find flight deals from Iowa to South Carolina

Cheapest flights from Iowa to South Carolina
Explore the most affordable flight options available from Iowa to South Carolina. Find the lowest fares from popular airlines and budget airlines, with prices last updated on December 22, 2024.

This Delta deal was found by Cheapflights users on 12/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/245:35 pmDSM - CLT
1 stop4h 53mDelta
Thu 1/27:05 amCLT - DSM
1 stop4h 55mDelta
Deal found 12/21$392
This American Airlines deal was found by Cheapflights users on 12/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/266:00 amOMA - CLT
Nonstop2h 47mAmerican Airlines
Wed 1/19:05 pmCLT - OMA
Nonstop2h 51mAmerican Airlines
Deal found 12/21$441
This Southwest deal was found by Cheapflights users on 12/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/236:30 amDSM - CLT
2 stops14h 15mSouthwest
Thu 1/27:20 amCLT - DSM
2 stops16h 40mSouthwest
Deal found 12/21$494
This Southwest deal was found by Cheapflights users on 12/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/216:05 pmOMA - CLT
1 stop5h 00mSouthwest
Thu 12/268:45 pmCLT - OMA
1 stop4h 40mSouthwest
Deal found 12/20$494
This Delta deal was found by Cheapflights users on 12/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 12/225:37 pmOMA - CLT
1 stop4h 53mDelta
Fri 12/276:03 amCLT - OMA
1 stop7h 29mDelta
Deal found 12/21$524
This American Airlines deal was found by Cheapflights users on 12/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/241:58 pmDSM - CLT
Nonstop2h 32mAmerican Airlines
Thu 1/29:30 pmCLT - DSM
Nonstop2h 29mAmerican Airlines
Deal found 12/21$525
This United deal was found by Cheapflights users on 12/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/245:40 amDSM - CLT
2 stops10h 43mUnited Airlines
Thu 1/26:45 amCLT - DSM
1 stop4h 56mUnited Airlines
Deal found 12/21$549
This American Airlines deal was found by Cheapflights users on 12/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/245:00 amCID - CLT
Nonstop2h 25mAmerican Airlines
Mon 12/308:49 pmCLT - CID
Nonstop2h 22mAmerican Airlines
Deal found 12/21$570
This United Airlines deal was found by Cheapflights users on 12/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/318:00 amDSM - GSP
1 stop5h 49mUnited Airlines
Tue 12/317:50 pmGSP - DSM
2 stops19h 38mUnited Airlines
Deal found 12/21$586
This Delta deal was found by Cheapflights users on 12/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/244:18 pmCID - CLT
1 stop6h 10mDelta
Mon 12/3012:00 pmCLT - CID
1 stop4h 38mDelta
Deal found 12/21$589
This Delta deal was found by Cheapflights users on 12/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/241:15 pmDSM - GSP
1 stop4h 59mDelta
Wed 1/811:54 amGSP - DSM
1 stop6h 42mDelta
Deal found 12/21$592
This American Airlines deal was found by Cheapflights users on 12/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/245:00 amDSM - GSP
1 stop5h 29mAmerican Airlines
Wed 1/85:21 amGSP - DSM
2 stops7h 14mAmerican Airlines
Deal found 12/21$597

Find flights from Iowa to South Carolina within your budget

Customize your flight search to find flights from Iowa to South Carolina that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated December 22, 2024.

Fly from

Any airport

Fly to

Any airport

Route

Depart

Return

Price

OmahaCharlotte

OMA - CLT

OMACLT

Omaha Eppley Airfield

Wed 3/5

3:58 pm-9:13 pm

1 stop28h 15m

Charlotte Douglas

Sun 3/9

10:03 pm-2:58 pm

1 stop17h 55m

$197

Des MoinesCharlotte

DSM - CLT

DSMCLT

Des Moines

Sat 2/15

6:30 am-12:04 pm

1 stop4h 34m

Charlotte Douglas

Sat 2/22

7:05 am-10:40 am

1 stop4h 35m

$230

OmahaCharlotte

OMA - CLT

OMACLT

Omaha Eppley Airfield

Sat 1/25

6:01 pm-8:15 am

1 stop13h 14m

Charlotte Douglas

Sun 1/26

12:15 pm-2:01 pm

Nonstop2h 46m

$236

Des MoinesCharlotte

DSM - CLT

DSMCLT

Des Moines

Sat 2/15

2:06 pm-5:30 pm

Nonstop2h 24m

Charlotte Douglas

Sat 2/22

11:00 am-4:26 pm

1 stop6h 26m

$293

Des MoinesCharleston

DSM - CHS

DSMCHS

Des Moines

Wed 2/26

6:30 am-12:25 pm

1 stop4h 55m

Charleston

Tue 3/4

6:40 am-10:40 am

1 stop5h 00m

$296

Des MoinesCharlotte

DSM - CLT

DSMCLT

Des Moines

Mon 1/13

2:41 pm-12:01 pm

2 stops20h 20m

Charlotte Douglas

Thu 1/16

6:10 am-3:50 pm

1 stop10h 40m

$297

Des MoinesCharleston

DSM - CHS

DSMCHS

Des Moines

Wed 2/12

3:28 pm-9:09 pm

1 stop4h 41m

Charleston

Sat 2/15

6:15 am-10:37 am

1 stop5h 22m

$301

Des MoinesCharleston

DSM - CHS

DSMCHS

Des Moines

Sat 1/18

1:01 pm-10:03 pm

2 stops8h 02m

Charleston

Sat 1/25

5:10 am-12:11 pm

2 stops8h 01m

$316

Des MoinesSavannah

DSM - SAV

DSMSAV

Des Moines

Thu 2/6

6:26 pm-11:57 pm

1 stop4h 31m

Savannah/Hilton Head

Tue 2/11

2:38 pm-5:36 pm

1 stop3h 58m

$316

Des MoinesMyrtle Beach

DSM - MYR

DSMMYR

Des Moines

Fri 2/7

7:12 pm-3:01 pm

2 stops18h 49m

Myrtle Beach Intl

Mon 2/10

9:11 am-6:22 pm

2 stops10h 11m

$326

Flights are sorted by cheapest round-trip flights first.

Deals found on 12/21

Showing 1-10 of 60 results
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Best time to book a flight from Iowa to South Carolina

Have a flexible travel schedule? Discover the best time to fly to South Carolina from Iowa with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Travel insights for flights from Iowa to South Carolina

Get recent, data-driven insights about flights from Iowa to South Carolina including ideal travel times, pricing trends, and more.

What is the cheapest month to book a flight from Iowa to South Carolina?

Currently, August is the cheapest month in which you can book a flight from Iowa to South Carolina (average of $217). Flying from Iowa to South Carolina in March is currently the most expensive (average of $335). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from IA to SC?

Find hourly flight availability from Iowa to South Carolina. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated December 22, 2024.

When flying from Iowa to South Carolina, the time of day you decide to fly out makes little to no difference towards the overall price you’ll pay on tickets.

Rainfall in South Carolina by month

Plan your trip to South Carolina by taking into account the average rainfall totals by month.

In terms of precipitation, rainfall in South Carolina ranges from 3.0 - 6.5 inches per month. July is typically the wettest month, when rainfall can reach 6.5 in. November is typically the driest time to visit South Carolina when rainfall is around 3.0 in.

Temperature in South Carolina by month

Plan your trip to South Carolina by taking into account the average temperature totals by month.

If weather is an important factor for your trip to South Carolina, use this chart to help with planning. For those seeking warmer temperatures, July is the ideal time of year to visit, when temperatures reach an average of 78.8 F. Travelers looking to avoid the cold should look outside of January, when temperatures are typically at their lowest (around 44.6 F).

Reviews of airlines servicing South Carolina

Get insights into the airlines that provide service to South Carolina. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to South Carolina. Reviews last updated December 22, 2024.
Read through reviews of airlines operating flights from Iowa to South Carolina, such as Delta, American Airlines and United Airlines. Users have also rated airlines in terms of entertainment options, comfort, food, crew/service, and boarding process.
8.1
Very good
4,804 reviews

Boarding

8.2

Crew

8.7

Entertainment

7.7

Comfort

8.1

Overall

8.1

Food

7.2

Reviews

1 / 10

We BARELY made the connection and when we got onboard we were treated like disobedient children who should have arrived earlier because we had to ask other passengers to move so we could sit with our kids. The flight attendants on the first flight were nice but the second one, they were snippy and fairly rude.

8.1
Very good
4,804 reviews
8.1
Very good
4,804 reviews

Boarding

8.2

Crew

8.7

Entertainment

7.7

Comfort

8.1

Overall

8.1

Food

7.2

Reviews

1 / 10

We BARELY made the connection and when we got onboard we were treated like disobedient children who should have arrived earlier because we had to ask other passengers to move so we could sit with our kids. The flight attendants on the first flight were nice but the second one, they were snippy and fairly rude.

8.0
Very good
9,537 reviews
8.1
Very good
4,804 reviews

Boarding

8.2

Crew

8.7

Entertainment

7.7

Comfort

8.1

Overall

8.1

Food

7.2

Reviews

1 / 10

We BARELY made the connection and when we got onboard we were treated like disobedient children who should have arrived earlier because we had to ask other passengers to move so we could sit with our kids. The flight attendants on the first flight were nice but the second one, they were snippy and fairly rude.

8.0
Very good
8,594 reviews
8.1
Very good
4,804 reviews

Boarding

8.2

Crew

8.7

Entertainment

7.7

Comfort

8.1

Overall

8.1

Food

7.2

Reviews

1 / 10

We BARELY made the connection and when we got onboard we were treated like disobedient children who should have arrived earlier because we had to ask other passengers to move so we could sit with our kids. The flight attendants on the first flight were nice but the second one, they were snippy and fairly rude.

7.4
Good
9,028 reviews
8.1
Very good
4,804 reviews

Boarding

8.2

Crew

8.7

Entertainment

7.7

Comfort

8.1

Overall

8.1

Food

7.2

Reviews

1 / 10

We BARELY made the connection and when we got onboard we were treated like disobedient children who should have arrived earlier because we had to ask other passengers to move so we could sit with our kids. The flight attendants on the first flight were nice but the second one, they were snippy and fairly rude.

7.4
Good
823 reviews
8.1
Very good
4,804 reviews

Boarding

8.2

Crew

8.7

Entertainment

7.7

Comfort

8.1

Overall

8.1

Food

7.2

Reviews

1 / 10

We BARELY made the connection and when we got onboard we were treated like disobedient children who should have arrived earlier because we had to ask other passengers to move so we could sit with our kids. The flight attendants on the first flight were nice but the second one, they were snippy and fairly rude.

Related info for your journey

Find useful and relevant information for your journey from Iowa to South Carolina. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
  • What are the cheapest airlines to fly from Iowa to South Carolina one-way?

    The cheapest airline one-way is Frontier, with whom users have recently found tickets for as low as $63. However, be on the lookout for offers from American Airlines and Delta, as they are both options that can get you from Iowa to South Carolina for a low price.

  • Can I find deals for flights from Iowa to South Carolina that include hotel bookings?

    Yes. In addition to deals on Iowa to South Carolina flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Iowa to South Carolina?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Iowa to South Carolina.

  • Can I find deals for business class flights from Iowa to South Carolina?

    Yes. Cheapflights offers flight deals from Iowa to South Carolina by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Iowa to South Carolina?

    Currently, August is the cheapest month in which you can book a flight from Iowa to South Carolina (average of $217). Flying from Iowa to South Carolina in March is currently the most expensive (average of $335). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Browse thousands of different options on Cheapflights for your next trip

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Alternative routes for Iowa to South Carolina

See prices for flight routes from nearby airports that may be better suited for you.

Top 3 airlines flying from Iowa to South Carolina

Discover the top 3 airlines that operate flights from Iowa to South Carolina. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated December 22, 2024.
AirlineCheapestAverageFlexibilityOn-time
American AirlinesCheapest$140Average$373FlexibilityNo cancel feeOn-time71%
DeltaCheapest$215Average$388FlexibilityNo cancel feeOn-timeN/A
United AirlinesCheapest$247Average$448FlexibilityNo cancel feeOn-time69%
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