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$81+ Cheap flights from Iowa to South Carolina

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 3/19. Fares are subject to change and may not be available on all flights or dates of travel.
DSM — CHS
feb. 25 — mar. 41
mar. 2/25
mar. 3/4
1 adult, Economy
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Cheap flight deals from Iowa to South Carolina

Keep the following information in mind while searching for Iowa to South Carolina flight deals. Data was last updated febrero 20, 2025.

Most accurate provider

FlightHub
3 stars

Most trusted provider

FlightHub
3 stars

Round-trip from

$162
(Mytrip)

One-way from

$81
(Frontier)

Popular in

December

Cheapest in

September

Average price

$366
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From Iowa to South Carolina
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One-way flight from Iowa to South Carolina
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Highest demand for flights based on searches. 7% potential increase in price ($32 potential increase over avg. RT price).
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Cheapest flight prices on average. 2% potential price decrease ($10 potential savings vs. average RT price).
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Average for round-trip flights in February 2025
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Find flight deals from Iowa to South Carolina

Cheapest flights from Iowa to South Carolina
Explore the most affordable flight options available from Iowa to South Carolina. Find the lowest fares from popular airlines and budget airlines, with prices last updated on febrero 20, 2025.

This Mytrip deal was found by Cheapflights users on 2/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
lun. 4/215:47 pmCID - CHS
1 stop15h 21mMultiple Airlines
lun. 4/2811:06 amCHS - CID
1 stop6h 51mMultiple Airlines
Deal found 2/19$162
This Gotogate deal was found by Cheapflights users on 2/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Gotogate is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
vie. 3/78:17 pmDSM - CLT
1 stop21h 37mFrontier
jue. 3/1310:53 pmCLT - DSM
1 stop21h 24mFrontier
Deal found 2/20$169
This Booking.com deal was found by Cheapflights users on 2/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Booking.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
vie. 4/43:44 pmOMA - CLT
1 stop26h 13mFrontier
dom. 4/610:31 pmCLT - OMA
1 stop17h 40mFrontier
Deal found 2/19$180
This Mytrip deal was found by Cheapflights users on 2/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
lun. 3/101:32 pmDSM - CHS
3 stops23h 32mMultiple Airlines
mié. 3/1210:48 amCHS - DSM
1 stop7h 45mMultiple Airlines
Deal found 2/20$218
This American Airlines deal was found by Cheapflights users on 2/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
lun. 3/106:35 amCID - CHS
1 stop6h 42mAmerican Airlines
sáb. 3/157:09 amCHS - CID
1 stop6h 51mAmerican Airlines
Deal found 2/20$229
This Mytrip deal was found by Cheapflights users on 2/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
jue. 3/208:26 pmCID - CLT
1 stop21h 38mFrontier
lun. 3/247:54 pmCLT - CID
1 stop24h 32mFrontier
Deal found 2/19$238
This Delta deal was found by Cheapflights users on 2/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mié. 3/125:30 amCID - CHS
1 stop4h 53mDelta
sáb. 3/154:30 pmCHS - CID
1 stop6h 53mDelta
Deal found 2/20$248
This American Airlines deal was found by Cheapflights users on 2/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mié. 4/97:25 amDSM - CAE
1 stop8h 07mAmerican Airlines
mar. 4/156:32 pmCAE - DSM
1 stop4h 35mAmerican Airlines
Deal found 2/20$249
This American Airlines deal was found by Cheapflights users on 2/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
vie. 3/72:06 pmDSM - CLT
Nonstop2h 24mAmerican Airlines
jue. 3/138:30 pmCLT - DSM
Nonstop2h 34mAmerican Airlines
Deal found 2/20$253
This Delta deal was found by Cheapflights users on 2/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mar. 3/116:20 amDSM - CHS
1 stop5h 00mDelta
vie. 3/146:00 amCHS - DSM
1 stop9h 10mDelta
Deal found 2/20$257
This Delta deal was found by Cheapflights users on 2/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mar. 4/15:45 amDSM - SAV
1 stop7h 01mDelta
mar. 4/86:00 amSAV - DSM
1 stop9h 08mDelta
Deal found 2/20$257
This United Airlines deal was found by Cheapflights users on 2/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mar. 3/111:41 pmDSM - CLT
1 stop8h 04mUnited Airlines
jue. 3/1310:46 amCLT - DSM
1 stop4h 33mUnited Airlines
Deal found 2/20$264

Find flights from Iowa to South Carolina within your budget

Customize your flight search to find flights from Iowa to South Carolina that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated febrero 20, 2025.

Fly from

Iowa

Fly to

South Carolina

Route

Depart

Return

Price

Cedar RapidsCharleston

CID - CHS

CIDCHS

Cedar Rapids

lun. 4/21

5:47 pm-10:08 am

1 stop15h 21m

Charleston

lun. 4/28

11:06 am-4:57 pm

1 stop6h 51m

$162

Des MoinesCharlotte

DSM - CLT

DSMCLT

Des Moines

vie. 3/7

8:17 pm-6:54 pm

1 stop21h 37m

Charlotte Douglas

jue. 3/13

10:53 pm-7:17 pm

1 stop21h 24m

$169

OmahaCharlotte

OMA - CLT

OMACLT

Omaha Eppley Airfield

vie. 4/4

3:44 pm-6:57 pm

1 stop26h 13m

Charlotte Douglas

dom. 4/6

10:31 pm-3:11 pm

1 stop17h 40m

$180

Des MoinesCharleston

DSM - CHS

DSMCHS

Des Moines

lun. 3/10

1:32 pm-2:04 pm

3 stops23h 32m

Charleston

mié. 3/12

10:48 am-5:33 pm

1 stop7h 45m

$218

Cedar RapidsCharleston

CID - CHS

CIDCHS

Cedar Rapids

lun. 3/10

6:35 am-2:17 pm

1 stop6h 42m

Charleston

sáb. 3/15

7:09 am-1:00 pm

1 stop6h 51m

$229

Cedar RapidsCharlotte

CID - CLT

CIDCLT

Cedar Rapids

jue. 3/20

8:26 pm-7:04 pm

1 stop21h 38m

Charlotte Douglas

lun. 3/24

7:54 pm-7:26 pm

1 stop24h 32m

$238

Des MoinesCharlotte

DSM - CLT

DSMCLT

Des Moines

sáb. 4/5

1:59 pm-5:24 pm

Nonstop2h 25m

Charlotte Douglas

mar. 4/8

8:39 pm-10:07 pm

Nonstop2h 28m

$243

Cedar RapidsCharleston

CID - CHS

CIDCHS

Cedar Rapids

mié. 3/12

5:30 am-11:23 am

1 stop4h 53m

Charleston

sáb. 3/15

4:30 pm-10:23 pm

1 stop6h 53m

$248

Des MoinesColumbia

DSM - CAE

DSMCAE

Des Moines

mié. 4/9

7:25 am-4:32 pm

1 stop8h 07m

Columbia Metropolitan

mar. 4/15

6:32 pm-10:07 pm

1 stop4h 35m

$249

Des MoinesCharleston

DSM - CHS

DSMCHS

Des Moines

mar. 3/11

6:20 am-12:20 pm

1 stop5h 00m

Charleston

vie. 3/14

6:00 am-2:10 pm

1 stop9h 10m

$257

Flights are sorted by cheapest round-trip flights first.

Deals found on 2/20

Showing 1-10 of 60 results
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Best time to book a flight from Iowa to South Carolina

Have a flexible travel schedule? Discover the best time to fly to South Carolina from Iowa with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Travel insights for flights from Iowa to South Carolina

Get recent, data-driven insights about flights from Iowa to South Carolina including ideal travel times, pricing trends, and more.

What is the cheapest month to book a flight from Iowa to South Carolina?

Currently, August is the cheapest month in which you can book a flight from Iowa to South Carolina (average of $217). Flying from Iowa to South Carolina in March is currently the most expensive (average of $335). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from IA to SC?

Find hourly flight availability from Iowa to South Carolina. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated febrero 20, 2025.

When flying from Iowa to South Carolina, the time of day you decide to fly out makes little to no difference towards the overall price you’ll pay on tickets.

Rainfall in South Carolina by month

Plan your trip to South Carolina by taking into account the average rainfall totals by month.

In terms of precipitation, rainfall in South Carolina ranges from 3.0 - 6.5 inches per month. July is typically the wettest month, when rainfall can reach 6.5 in. November is typically the driest time to visit South Carolina when rainfall is around 3.0 in.

Temperature in South Carolina by month

Plan your trip to South Carolina by taking into account the average temperature totals by month.

If weather is an important factor for your trip to South Carolina, use this chart to help with planning. For those seeking warmer temperatures, July is the ideal time of year to visit, when temperatures reach an average of 78.8 F. Travelers looking to avoid the cold should look outside of January, when temperatures are typically at their lowest (around 44.6 F).

Reviews of airlines servicing South Carolina

Get insights into the airlines that provide service to South Carolina. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to South Carolina. Reviews last updated febrero 20, 2025.
Read through reviews of airlines operating flights from Iowa to South Carolina, such as Southwest, Alaska Airlines and Delta. Users have also rated airlines in terms of entertainment options, comfort, food, crew/service, and boarding process.
Southwest
8.1
Very good
4,411 reviews

Entertainment

7.6

Boarding

8.2

Food

7.1

Comfort

8.1

Overall

8.1

Crew

8.7

Reviews

1 / 20

2.0
Mediocre

Anonymous,Feb 2025

MCO - STL

Cancelled at last minute, SWA unable to assist in formulating alternate plans. Wound up renting a car and driving 13 hours to beat bad weather forecast at home. Not SWA’s fault that there was significant bad weather across the country.

Southwest
8.1
Very good
4,411 reviews
Southwest
8.1
Very good
4,411 reviews

Entertainment

7.6

Boarding

8.2

Food

7.1

Comfort

8.1

Overall

8.1

Crew

8.7

Reviews

1 / 20

2.0
Mediocre

Anonymous,Feb 2025

MCO - STL

Cancelled at last minute, SWA unable to assist in formulating alternate plans. Wound up renting a car and driving 13 hours to beat bad weather forecast at home. Not SWA’s fault that there was significant bad weather across the country.

Alaska Airlines
8.0
Very good
9,692 reviews
Southwest
8.1
Very good
4,411 reviews

Entertainment

7.6

Boarding

8.2

Food

7.1

Comfort

8.1

Overall

8.1

Crew

8.7

Reviews

1 / 20

2.0
Mediocre

Anonymous,Feb 2025

MCO - STL

Cancelled at last minute, SWA unable to assist in formulating alternate plans. Wound up renting a car and driving 13 hours to beat bad weather forecast at home. Not SWA’s fault that there was significant bad weather across the country.

Delta
8.0
Very good
8,220 reviews
Southwest
8.1
Very good
4,411 reviews

Entertainment

7.6

Boarding

8.2

Food

7.1

Comfort

8.1

Overall

8.1

Crew

8.7

Reviews

1 / 20

2.0
Mediocre

Anonymous,Feb 2025

MCO - STL

Cancelled at last minute, SWA unable to assist in formulating alternate plans. Wound up renting a car and driving 13 hours to beat bad weather forecast at home. Not SWA’s fault that there was significant bad weather across the country.

United Airlines
7.4
Good
8,766 reviews
Southwest
8.1
Very good
4,411 reviews

Entertainment

7.6

Boarding

8.2

Food

7.1

Comfort

8.1

Overall

8.1

Crew

8.7

Reviews

1 / 20

2.0
Mediocre

Anonymous,Feb 2025

MCO - STL

Cancelled at last minute, SWA unable to assist in formulating alternate plans. Wound up renting a car and driving 13 hours to beat bad weather forecast at home. Not SWA’s fault that there was significant bad weather across the country.

Allegiant Air
7.3
Good
765 reviews
Southwest
8.1
Very good
4,411 reviews

Entertainment

7.6

Boarding

8.2

Food

7.1

Comfort

8.1

Overall

8.1

Crew

8.7

Reviews

1 / 20

2.0
Mediocre

Anonymous,Feb 2025

MCO - STL

Cancelled at last minute, SWA unable to assist in formulating alternate plans. Wound up renting a car and driving 13 hours to beat bad weather forecast at home. Not SWA’s fault that there was significant bad weather across the country.

Related info for your journey

Find useful and relevant information for your journey from Iowa to South Carolina. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What are the cheapest airlines to fly from Iowa to South Carolina one-way?

    The cheapest airline one-way is Frontier, with whom users have recently found tickets for as low as $81. However, be on the lookout for offers from American Airlines and United Airlines, as they are both options that can get you from Iowa to South Carolina for a low price.

  • Can I find deals for flights from Iowa to South Carolina that include hotel bookings?

    Yes. In addition to deals on Iowa to South Carolina flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Iowa to South Carolina?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Iowa to South Carolina.

  • Can I find deals for business class flights from Iowa to South Carolina?

    Yes. Cheapflights offers flight deals from Iowa to South Carolina by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Iowa to South Carolina?

    Currently, August is the cheapest month in which you can book a flight from Iowa to South Carolina (average of $217). Flying from Iowa to South Carolina in March is currently the most expensive (average of $335). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

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Alternative routes for Iowa to South Carolina

See prices for flight routes from nearby airports that may be better suited for you.
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Top 3 airlines flying from Iowa to South Carolina

Discover the top 3 airlines that operate flights from Iowa to South Carolina. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated febrero 20, 2025.
AirlineCheapestAverageFlexibilityOn-time
American AirlinesCheapest$140Average$375FlexibilityNo cancel feeOn-time71%
DeltaCheapest$216Average$370FlexibilityNo cancel feeOn-timeN/A
United AirlinesCheapest$248Average$422FlexibilityNo cancel feeOn-time69%
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