South Carolina

$61+ Cheap flights from Iowa to South Carolina

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 3/19. Fares are subject to change and may not be available on all flights or dates of travel.
DSM — CHS
Jan 26 — Feb 21
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Cheap flight deals from Iowa to South Carolina

Discover tips and strategies to find the most affordable flight options for your journey from Iowa (USIA) to South Carolina (USSC). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated January 21, 2025.

Round-trip from

$179
(CheapOair)

One-way from

$61
(Frontier)
From Iowa to South Carolina
One-way flight from Iowa to South Carolina

Find flight deals from Iowa to South Carolina

Cheapest flights from Iowa to South Carolina
Explore the most affordable flight options available from Iowa to South Carolina. Find the lowest fares from popular airlines and budget airlines, with prices last updated on January 21, 2025.

This CheapOair deal was found by Cheapflights users on 1/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 2/219:43 amOMA - CLT
1 stop20h 25mFrontier
Sun 3/27:54 pmCLT - OMA
1 stop20h 08mFrontier
Deal found 1/21$179
This Booking.com deal was found by Cheapflights users on 1/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Booking.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/77:20 pmDSM - CLT
1 stop19h 45mFrontier
Sun 5/115:06 pmCLT - DSM
1 stop26h 24mFrontier
Deal found 1/19$220
This Mytrip deal was found by Cheapflights users on 1/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 3/13:04 pmDSM - CLT
2 stops19h 09mMultiple Airlines
Tue 3/49:38 pmCLT - DSM
1 stop17h 03mMultiple Airlines
Deal found 1/20$241
This American Airlines deal was found by Cheapflights users on 1/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 3/264:23 pmMLI - SAV
1 stop6h 31mAmerican Airlines
Wed 4/210:52 amSAV - MLI
1 stop5h 56mAmerican Airlines
Deal found 1/21$249
This Delta deal was found by Cheapflights users on 1/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 4/275:45 amCID - SAV
1 stop4h 34mDelta
Sat 5/34:27 pmSAV - CID
1 stop6h 53mDelta
Deal found 1/20$249
This American Airlines deal was found by Cheapflights users on 1/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/161:59 pmDSM - SAV
1 stop4h 44mAmerican Airlines
Wed 4/239:03 amSAV - DSM
1 stop5h 10mAmerican Airlines
Deal found 1/21$257
This Mytrip deal was found by Cheapflights users on 1/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 3/59:11 pmCID - CLT
2 stops19h 41mMultiple Airlines
Mon 3/106:52 amCLT - CID
1 stop10h 55mMultiple Airlines
Deal found 1/20$258
This United Airlines deal was found by Cheapflights users on 1/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 2/48:15 amCID - SAV
2 stops10h 15mUnited Airlines
Mon 2/102:05 pmSAV - CID
2 stops8h 27mUnited Airlines
Deal found 1/20$264
This American Airlines deal was found by Cheapflights users on 1/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 3/2612:20 pmCID - SAV
1 stop5h 47mAmerican Airlines
Wed 4/24:16 pmSAV - CID
1 stop6h 28mAmerican Airlines
Deal found 1/20$279
This Delta deal was found by Cheapflights users on 1/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 1/295:05 pmMLI - SAV
1 stop5h 52mDelta
Mon 2/37:12 pmSAV - MLI
1 stop4h 26mDelta
Deal found 1/20$289
This Mytrip deal was found by Cheapflights users on 1/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 2/107:29 pmOMA - CLT
2 stops20h 37mMultiple Airlines
Wed 2/129:38 pmCLT - OMA
2 stops23h 00mMultiple Airlines
Deal found 1/21$289
This Delta deal was found by Cheapflights users on 1/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 2/47:05 amDSM - CHS
1 stop5h 52mDelta
Sat 2/86:00 amCHS - DSM
1 stop5h 40mDelta
Deal found 1/20$297

Find flights from Iowa to South Carolina within your budget

Customize your flight search to find flights from Iowa to South Carolina that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated January 21, 2025.

Fly from

Any airport

Fly to

Any airport

Route

Depart

Return

Price

OmahaCharlotte

OMA - CLT

OMACLT

Omaha Eppley Airfield

Fri 2/21

9:43 am-7:08 am

1 stop20h 25m

Charlotte Douglas

Sun 3/2

7:54 pm-3:02 pm

1 stop20h 08m

$179

Des MoinesCharlotte

DSM - CLT

DSMCLT

Des Moines

Wed 5/7

7:20 pm-4:05 pm

1 stop19h 45m

Charlotte Douglas

Sun 5/11

5:06 pm-6:30 pm

1 stop26h 24m

$220

Des MoinesCharlotte

DSM - CLT

DSMCLT

Des Moines

Sat 3/1

3:04 pm-11:13 am

2 stops19h 09m

Charlotte Douglas

Tue 3/4

9:38 pm-1:41 pm

1 stop17h 03m

$241

MolineSavannah

MLI - SAV

MLISAV

Moline Quad-City

Wed 3/26

4:23 pm-11:54 pm

1 stop6h 31m

Savannah/Hilton Head

Wed 4/2

10:52 am-3:48 pm

1 stop5h 56m

$249

Cedar RapidsSavannah

CID - SAV

CIDSAV

Cedar Rapids

Sun 4/27

5:45 am-11:19 am

1 stop4h 34m

Savannah/Hilton Head

Sat 5/3

4:27 pm-10:20 pm

1 stop6h 53m

$249

Des MoinesSavannah

DSM - SAV

DSMSAV

Des Moines

Tue 3/18

2:07 pm-9:52 pm

1 stop6h 45m

Savannah/Hilton Head

Tue 3/25

7:43 am-12:19 pm

1 stop5h 36m

$257

Cedar RapidsCharlotte

CID - CLT

CIDCLT

Cedar Rapids

Wed 3/5

9:11 pm-5:52 pm

2 stops19h 41m

Charlotte Douglas

Mon 3/10

6:52 am-4:47 pm

1 stop10h 55m

$258

Cedar RapidsSavannah

CID - SAV

CIDSAV

Cedar Rapids

Tue 2/4

8:15 am-7:30 pm

2 stops10h 15m

Savannah/Hilton Head

Mon 2/10

2:05 pm-9:32 pm

2 stops8h 27m

$264

Cedar RapidsSavannah

CID - SAV

CIDSAV

Cedar Rapids

Wed 3/26

12:20 pm-7:07 pm

1 stop5h 47m

Savannah/Hilton Head

Wed 4/2

4:16 pm-9:44 pm

1 stop6h 28m

$279

OmahaCharlotte

OMA - CLT

OMACLT

Omaha Eppley Airfield

Mon 2/10

7:29 pm-5:06 pm

2 stops20h 37m

Charlotte Douglas

Wed 2/12

9:38 pm-7:38 pm

2 stops23h 00m

$289

Flights are sorted by cheapest round-trip flights first.

Deals found on 1/20

Showing 1-10 of 60 results
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Best time to book a flight from Iowa to South Carolina

Have a flexible travel schedule? Discover the best time to fly to South Carolina from Iowa with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Travel insights for flights from Iowa to South Carolina

Get recent, data-driven insights about flights from Iowa to South Carolina including ideal travel times, pricing trends, and more.

What is the cheapest month to book a flight from Iowa to South Carolina?

Currently, August is the cheapest month in which you can book a flight from Iowa to South Carolina (average of $217). Flying from Iowa to South Carolina in March is currently the most expensive (average of $335). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from IA to SC?

Find hourly flight availability from Iowa to South Carolina. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated January 21, 2025.

When flying from Iowa to South Carolina, the time of day you decide to fly out makes little to no difference towards the overall price you’ll pay on tickets.

Rainfall in South Carolina by month

Plan your trip to South Carolina by taking into account the average rainfall totals by month.

In terms of precipitation, rainfall in South Carolina ranges from 3.0 - 6.5 inches per month. July is typically the wettest month, when rainfall can reach 6.5 in. November is typically the driest time to visit South Carolina when rainfall is around 3.0 in.

Temperature in South Carolina by month

Plan your trip to South Carolina by taking into account the average temperature totals by month.

If weather is an important factor for your trip to South Carolina, use this chart to help with planning. For those seeking warmer temperatures, July is the ideal time of year to visit, when temperatures reach an average of 78.8 F. Travelers looking to avoid the cold should look outside of January, when temperatures are typically at their lowest (around 44.6 F).

Reviews of airlines servicing South Carolina

Get insights into the airlines that provide service to South Carolina. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to South Carolina. Reviews last updated January 21, 2025.
Read through reviews of airlines operating flights from Iowa to South Carolina, such as Frontier, Southwest and Delta. Users have also rated airlines in terms of entertainment options, comfort, food, crew/service, and boarding process.
8.1
Very good
4,662 reviews

Comfort

8.1

Overall

8.1

Boarding

8.2

Food

7.2

Crew

8.7

Entertainment

7.7

Reviews

1 / 10

We BARELY made the connection and when we got onboard we were treated like disobedient children who should have arrived earlier because we had to ask other passengers to move so we could sit with our kids. The flight attendants on the first flight were nice but the second one, they were snippy and fairly rude.

8.1
Very good
4,662 reviews
8.1
Very good
4,662 reviews

Comfort

8.1

Overall

8.1

Boarding

8.2

Food

7.2

Crew

8.7

Entertainment

7.7

Reviews

1 / 10

We BARELY made the connection and when we got onboard we were treated like disobedient children who should have arrived earlier because we had to ask other passengers to move so we could sit with our kids. The flight attendants on the first flight were nice but the second one, they were snippy and fairly rude.

8.0
Very good
9,706 reviews
8.1
Very good
4,662 reviews

Comfort

8.1

Overall

8.1

Boarding

8.2

Food

7.2

Crew

8.7

Entertainment

7.7

Reviews

1 / 10

We BARELY made the connection and when we got onboard we were treated like disobedient children who should have arrived earlier because we had to ask other passengers to move so we could sit with our kids. The flight attendants on the first flight were nice but the second one, they were snippy and fairly rude.

8.0
Very good
8,521 reviews
8.1
Very good
4,662 reviews

Comfort

8.1

Overall

8.1

Boarding

8.2

Food

7.2

Crew

8.7

Entertainment

7.7

Reviews

1 / 10

We BARELY made the connection and when we got onboard we were treated like disobedient children who should have arrived earlier because we had to ask other passengers to move so we could sit with our kids. The flight attendants on the first flight were nice but the second one, they were snippy and fairly rude.

7.4
Good
8,984 reviews
8.1
Very good
4,662 reviews

Comfort

8.1

Overall

8.1

Boarding

8.2

Food

7.2

Crew

8.7

Entertainment

7.7

Reviews

1 / 10

We BARELY made the connection and when we got onboard we were treated like disobedient children who should have arrived earlier because we had to ask other passengers to move so we could sit with our kids. The flight attendants on the first flight were nice but the second one, they were snippy and fairly rude.

7.4
Good
801 reviews
8.1
Very good
4,662 reviews

Comfort

8.1

Overall

8.1

Boarding

8.2

Food

7.2

Crew

8.7

Entertainment

7.7

Reviews

1 / 10

We BARELY made the connection and when we got onboard we were treated like disobedient children who should have arrived earlier because we had to ask other passengers to move so we could sit with our kids. The flight attendants on the first flight were nice but the second one, they were snippy and fairly rude.

Related info for your journey

Find useful and relevant information for your journey from Iowa to South Carolina. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
  • What are the cheapest airlines to fly from Iowa to South Carolina one-way?

    The cheapest airline one-way is Frontier, with whom users have recently found tickets for as low as $61. However, be on the lookout for offers from American Airlines and Delta, as they are both options that can get you from Iowa to South Carolina for a low price.

  • Can I find deals for flights from Iowa to South Carolina that include hotel bookings?

    Yes. In addition to deals on Iowa to South Carolina flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Iowa to South Carolina?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Iowa to South Carolina.

  • Can I find deals for business class flights from Iowa to South Carolina?

    Yes. Cheapflights offers flight deals from Iowa to South Carolina by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Iowa to South Carolina?

    Currently, August is the cheapest month in which you can book a flight from Iowa to South Carolina (average of $217). Flying from Iowa to South Carolina in March is currently the most expensive (average of $335). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Browse thousands of different options on Cheapflights for your next trip

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Alternative routes for Iowa to South Carolina

See prices for flight routes from nearby airports that may be better suited for you.

Top 3 airlines flying from Iowa to South Carolina

Discover the top 3 airlines that operate flights from Iowa to South Carolina. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated January 21, 2025.
AirlineCheapestAverageFlexibilityOn-time
American AirlinesCheapest$140Average$378FlexibilityNo cancel feeOn-time71%
DeltaCheapest$215Average$386FlexibilityNo cancel feeOn-timeN/A
United AirlinesCheapest$247Average$432FlexibilityNo cancel feeOn-time69%
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