HomeSearch by dateVacation packagesHotelsFlight dealsCar rentalTravel tips & news
South Carolina

$46+ Cheap flights from Indiana to South Carolina

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 2/26. Fares are subject to change and may not be available on all flights or dates of travel.
IND — CHS
Jan 26 — Feb 21
Sun 1/26
Sun 2/2
1 adult, Economy
We work with more than 300 partners to bring you better travel deals

Find cheap flights from Indiana to South Carolina with Cheapflights

1. Tell us where you want to go
Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”
2. Select your favorite providers
We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.
3. Compare prices and book
Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.

Cheap flight deals from Indiana to South Carolina

Discover tips and strategies to find the most affordable flight options for your journey from Indiana (USIN) to South Carolina (USSC). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated January 21, 2025.

Round-trip from

$119
(Frontier)

One-way from

$46
(FlightHub)

Good round-trip deal

$142 or less
From Indiana to South Carolina
Search Deals
One-way flight from Indiana to South Carolina
Search Deals
Price to beat on a round-trip flight from Indiana to South Carolina.
Search Deals

Find flight deals from Indiana to South Carolina

Cheapest flights from Indiana to South Carolina
Explore the most affordable flight options available from Indiana to South Carolina. Find the lowest fares from popular airlines and budget airlines, with prices last updated on January 21, 2025.

This Frontier deal was found by Cheapflights users on 1/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 2/287:18 pmORD - CLT
1 stop10h 50mFrontier
Mon 3/39:46 pmCLT - ORD
1 stop13h 05mFrontier
Deal found 1/20$119
This Flightnetwork deal was found by Cheapflights users on 1/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Flightnetwork is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 3/65:01 amCVG - CLT
1 stop13h 28mFrontier
Thu 3/137:19 pmCLT - CVG
1 stop5h 35mFrontier
Deal found 1/19$120
This Frontier deal was found by Cheapflights users on 1/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 2/77:15 amMDW - CLT
1 stop7h 53mFrontier
Mon 2/1012:46 pmCLT - MDW
1 stop10h 53mFrontier
Deal found 1/20$120
This Cheapflightsfares deal was found by Cheapflights users on 1/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 1/2512:25 pmORD - CLT
1 stop6h 25mSpirit Airlines
Tue 1/286:07 pmCLT - ORD
1 stop5h 48mSpirit Airlines
Deal found 1/19$120
This CheapOair deal was found by Cheapflights users on 1/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 2/2712:59 pmORD - CLT
Nonstop2h 10mMultiple Airlines
Sun 3/27:17 amCLT - ORD
1 stop6h 20mMultiple Airlines
Deal found 1/20$124
This Cheapflightsfares deal was found by Cheapflights users on 1/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 3/1512:31 pmORD - MYR
1 stop8h 33mSpirit Airlines
Wed 3/196:30 amMYR - ORD
1 stop5h 45mSpirit Airlines
Deal found 1/21$145
This Southwest deal was found by Cheapflights users on 1/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 2/188:40 amMDW - CLT
Nonstop1h 55mSouthwest
Tue 2/256:20 amCLT - MDW
Nonstop2h 00mSouthwest
Deal found 1/21$157
This United Airlines deal was found by Cheapflights users on 1/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 3/46:00 pmORD - CLT
Nonstop2h 02mUnited Airlines
Mon 3/1010:46 amCLT - ORD
Nonstop2h 17mUnited Airlines
Deal found 1/20$157
This American Airlines deal was found by Cheapflights users on 1/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 3/44:41 pmORD - CLT
Nonstop1h 53mAmerican Airlines
Wed 3/1211:19 amCLT - ORD
Nonstop2h 13mAmerican Airlines
Deal found 1/20$163
This Mytrip deal was found by Cheapflights users on 1/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 3/64:57 pmCVG - CLT
1 stop6h 37mMultiple Airlines
Thu 3/1312:15 pmCLT - CVG
1 stop10h 49mMultiple Airlines
Deal found 1/21$170
This Delta deal was found by Cheapflights users on 1/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 2/2010:57 amMDW - CLT
1 stop4h 08mDelta
Thu 2/277:05 amCLT - MDW
1 stop4h 07mDelta
Deal found 1/21$197
This Delta deal was found by Cheapflights users on 1/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 2/206:45 amORD - CLT
1 stop4h 19mDelta
Sun 2/234:59 pmCLT - ORD
1 stop4h 54mDelta
Deal found 1/21$197

Find flights from Indiana to South Carolina within your budget

Customize your flight search to find flights from Indiana to South Carolina that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated January 21, 2025.

Fly from

Any airport

Fly to

Any airport

Route

Depart

Return

Price

ChicagoCharlotte

ORD - CLT

ORDCLT

Chicago O'Hare Intl

Fri 2/28

7:18 pm-7:08 am

1 stop10h 50m

Charlotte Douglas

Mon 3/3

9:46 pm-9:51 am

1 stop13h 05m

$119

CincinnatiCharlotte

CVG - CLT

CVGCLT

Cincinnati Cinci./N. Kentucky

Thu 3/6

5:01 am-6:29 pm

1 stop13h 28m

Charlotte Douglas

Thu 3/13

7:19 pm-12:54 am

1 stop5h 35m

$120

ChicagoCharlotte

MDW - CLT

MDWCLT

Chicago Midway

Fri 2/7

7:15 am-4:08 pm

1 stop7h 53m

Charlotte Douglas

Mon 2/10

12:46 pm-10:39 pm

1 stop10h 53m

$120

ChicagoCharlotte

ORD - CLT

ORDCLT

Chicago O'Hare Intl

Thu 2/27

12:59 pm-4:09 pm

Nonstop2h 10m

Charlotte Douglas

Sun 3/2

7:17 am-12:37 pm

1 stop6h 20m

$124

ChicagoCharlotte

ORD - CLT

ORDCLT

Chicago O'Hare Intl

Tue 2/18

5:15 am-5:36 pm

1 stop11h 21m

Charlotte Douglas

Tue 2/25

4:18 pm-11:58 pm

1 stop8h 40m

$126

ChicagoMyrtle Beach

ORD - MYR

ORDMYR

Chicago O'Hare Intl

Sun 2/2

5:50 am-3:01 pm

1 stop8h 11m

Myrtle Beach Intl

Thu 2/6

9:11 am-2:32 pm

1 stop6h 21m

$146

ChicagoCharlotte

MDW - CLT

MDWCLT

Chicago Midway

Tue 2/18

8:40 am-11:35 am

Nonstop1h 55m

Charlotte Douglas

Tue 2/25

6:20 am-7:20 am

Nonstop2h 00m

$157

ChicagoCharlotte

ORD - CLT

ORDCLT

Chicago O'Hare Intl

Tue 3/4

2:00 pm-5:02 pm

Nonstop2h 02m

Charlotte Douglas

Tue 3/11

6:40 am-8:00 am

Nonstop2h 20m

$157

ChicagoCharlotte

ORD - CLT

ORDCLT

Chicago O'Hare Intl

Tue 3/4

4:41 pm-7:34 pm

Nonstop1h 53m

Charlotte Douglas

Wed 3/12

11:19 am-12:32 pm

Nonstop2h 13m

$163

CincinnatiCharlotte

CVG - CLT

CVGCLT

Cincinnati Cinci./N. Kentucky

Thu 3/6

4:57 pm-11:34 pm

1 stop6h 37m

Charlotte Douglas

Thu 3/13

12:15 pm-11:04 pm

1 stop10h 49m

$170

Flights are sorted by cheapest round-trip flights first.

Deals found on 1/20

Showing 1-10 of 60 results
1
2
3
...
6

Best time to book a flight from Indiana to South Carolina

Have a flexible travel schedule? Discover the best time to fly to South Carolina from Indiana with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Travel insights for flights from Indiana to South Carolina

Get recent, data-driven insights about flights from Indiana to South Carolina including ideal travel times, pricing trends, and more.

What is the cheapest month to book a flight from Indiana to South Carolina?

Currently, August is the cheapest month in which you can book a flight from Indiana to South Carolina (average of $217). Flying from Indiana to South Carolina in March is currently the most expensive (average of $335). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from IN to SC?

Find hourly flight availability from Indiana to South Carolina. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated January 21, 2025.

When flying from Indiana to South Carolina, the time of day you decide to fly out makes little to no difference towards the overall price you’ll pay on tickets.

Rainfall in South Carolina by month

Plan your trip to South Carolina by taking into account the average rainfall totals by month.

In terms of precipitation, rainfall in South Carolina ranges from 3.0 - 6.5 inches per month. July is typically the wettest month, when rainfall can reach 6.5 in. November is typically the driest time to visit South Carolina when rainfall is around 3.0 in.

Temperature in South Carolina by month

Plan your trip to South Carolina by taking into account the average temperature totals by month.

If weather is an important factor for your trip to South Carolina, use this chart to help with planning. For those seeking warmer temperatures, July is the ideal time of year to visit, when temperatures reach an average of 78.8 F. Travelers looking to avoid the cold should look outside of January, when temperatures are typically at their lowest (around 44.6 F).

Reviews of airlines servicing South Carolina

Get insights into the airlines that provide service to South Carolina. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to South Carolina. Reviews last updated January 21, 2025.
Read through reviews of airlines operating flights from Indiana to South Carolina, such as Southwest, United Airlines and Frontier. Users can see the overall rating for each airline as well as how each is rated in terms of entertainment options, comfort, food, crew/service, and boarding process.
Southwest
8.1
Very good
4,662 reviews

Comfort

8.1

Boarding

8.2

Crew

8.7

Entertainment

7.7

Overall

8.1

Food

7.2

Reviews

1 / 10

We BARELY made the connection and when we got onboard we were treated like disobedient children who should have arrived earlier because we had to ask other passengers to move so we could sit with our kids. The flight attendants on the first flight were nice but the second one, they were snippy and fairly rude.

Southwest
8.1
Very good
4,662 reviews
Southwest
8.1
Very good
4,662 reviews

Comfort

8.1

Boarding

8.2

Crew

8.7

Entertainment

7.7

Overall

8.1

Food

7.2

Reviews

1 / 10

We BARELY made the connection and when we got onboard we were treated like disobedient children who should have arrived earlier because we had to ask other passengers to move so we could sit with our kids. The flight attendants on the first flight were nice but the second one, they were snippy and fairly rude.

Delta
8.0
Very good
8,521 reviews
Southwest
8.1
Very good
4,662 reviews

Comfort

8.1

Boarding

8.2

Crew

8.7

Entertainment

7.7

Overall

8.1

Food

7.2

Reviews

1 / 10

We BARELY made the connection and when we got onboard we were treated like disobedient children who should have arrived earlier because we had to ask other passengers to move so we could sit with our kids. The flight attendants on the first flight were nice but the second one, they were snippy and fairly rude.

JetBlue
7.4
Good
3,201 reviews
Southwest
8.1
Very good
4,662 reviews

Comfort

8.1

Boarding

8.2

Crew

8.7

Entertainment

7.7

Overall

8.1

Food

7.2

Reviews

1 / 10

We BARELY made the connection and when we got onboard we were treated like disobedient children who should have arrived earlier because we had to ask other passengers to move so we could sit with our kids. The flight attendants on the first flight were nice but the second one, they were snippy and fairly rude.

United Airlines
7.4
Good
8,985 reviews
Southwest
8.1
Very good
4,662 reviews

Comfort

8.1

Boarding

8.2

Crew

8.7

Entertainment

7.7

Overall

8.1

Food

7.2

Reviews

1 / 10

We BARELY made the connection and when we got onboard we were treated like disobedient children who should have arrived earlier because we had to ask other passengers to move so we could sit with our kids. The flight attendants on the first flight were nice but the second one, they were snippy and fairly rude.

Allegiant Air
7.4
Good
801 reviews
Southwest
8.1
Very good
4,662 reviews

Comfort

8.1

Boarding

8.2

Crew

8.7

Entertainment

7.7

Overall

8.1

Food

7.2

Reviews

1 / 10

We BARELY made the connection and when we got onboard we were treated like disobedient children who should have arrived earlier because we had to ask other passengers to move so we could sit with our kids. The flight attendants on the first flight were nice but the second one, they were snippy and fairly rude.

Related info for your journey

Find useful and relevant information for your journey from Indiana to South Carolina. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How popular is this Indiana to South Carolina flight route?

    This flight path from Indiana to South Carolina was viewed by 1 users in the past month. Keep an eye out for changes in search interest prior to high and low season.

  • What are the cheapest airlines to fly from Indiana to South Carolina one-way?

    $46 is the cheapest one-way deal found within the past few days, from Spirit Airlines. You may also be able to find cheap deals on Frontier and Allegiant Air, with prices starting from $54 and $58, respectively.

  • Can I find deals for flights from Indiana to South Carolina that include hotel bookings?

    Yes. In addition to deals on Indiana to South Carolina flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Indiana to South Carolina?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Indiana to South Carolina.

  • Can I find deals for business class flights from Indiana to South Carolina?

    Yes. Cheapflights offers flight deals from Indiana to South Carolina by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Indiana to South Carolina?

    Currently, August is the cheapest month in which you can book a flight from Indiana to South Carolina (average of $217). Flying from Indiana to South Carolina in March is currently the most expensive (average of $335). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Browse thousands of different options on Cheapflights for your next trip

Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.

Alternative routes for Indiana to South Carolina

See prices for flight routes from nearby airports that may be better suited for you.
John F Kennedy Intl to Miami flights
John F Kennedy Intl to Fort Lauderdale flights
Newark to Fort Lauderdale flights
LaGuardia to Fort Lauderdale flights
John F Kennedy Intl to Orlando flights
Newark to Miami flights
LaGuardia to Miami flights
Newark to Orlando flights
LaGuardia to Dallas/Fort Worth flights
Reagan-National to Miami flights
LaGuardia to Orlando flights
John F Kennedy Intl to West Palm Beach flights
John F Kennedy Intl to Las Vegas flights
John F Kennedy Intl to Los Angeles flights
Los Angeles to John F Kennedy Intl flights
Dulles Intl to Miami flights
Newark to Los Angeles flights
Boston to Fort Lauderdale flights
O'Hare Intl to Las Vegas flights
Los Angeles to Newark flights
O'Hare Intl to Orlando flights
O'Hare Intl to Sky Harbor Intl flights
Dallas/Fort Worth to Las Vegas flights
Boston to Orlando flights
Minneapolis to Sky Harbor Intl flights
Los Angeles to Dallas/Fort Worth flights
Dulles Intl to Orlando flights
John F Kennedy Intl to San Francisco flights
Dallas/Fort Worth to Orlando flights
Seattle to Sky Harbor Intl flights
Minneapolis to Las Vegas flights
John F Kennedy Intl to Dallas/Fort Worth flights
Philadelphia to Orlando flights
Dallas/Fort Worth to LaGuardia flights
O'Hare Intl to Fort Lauderdale flights
San Francisco to John F Kennedy Intl flights
John F Kennedy Intl to Sky Harbor Intl flights
Newark to Tampa flights
Detroit to Orlando flights
Boston to Miami flights
Los Angeles to Seattle flights
Dallas/Fort Worth to John F Kennedy Intl flights
John F Kennedy Intl to New Orleans flights
John F Kennedy Intl to Atlanta flights
O'Hare Intl to Miami flights
O'Hare Intl to John F Kennedy Intl flights
Denver to Las Vegas flights
O'Hare Intl to Dallas/Fort Worth flights
LaGuardia to New Orleans flights
Seattle to Las Vegas flights

Top 6 airlines flying from Indiana to South Carolina

Discover the top 6 airlines that operate flights from Indiana to South Carolina. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated January 21, 2025.
AirlineCheapestAverageFlexibilityOn-time
Allegiant AirCheapest$86Average$167FlexibilityNo cancel feeOn-time88%
Spirit AirlinesCheapest$110Average$183FlexibilityNo cancel feeOn-time65%
United AirlinesCheapest$195Average$403FlexibilityNo cancel feeOn-time69%
American AirlinesCheapest$198Average$415FlexibilityNo cancel feeOn-time71%
DeltaCheapest$198Average$357FlexibilityNo cancel feeOn-timeN/A
SouthwestCheapest$257Average$371FlexibilityNo cancel feeOn-time63%
100% Free
Cheapflights is completely free to use, so you can start saving the moment you arrive.
Book with Flexibility
Our users can plan ahead with confidence and find flights with no change fees
Travel Smart
Millions of people come to us for their flight needs every year. We help make travel planning easy by providing useful insights and data-driven graphs that can inform your decisions.