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South Carolina

$65+ Cheap flights from Harrisburg (MDT) to South Carolina

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 5/4. Fares are subject to change and may not be available on all flights or dates of travel.
MDT — CHS
Apr 29 — May 61
Tue 4/29
Tue 5/6
1 adult, Economy
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Cheap flight deals from Harrisburg to South Carolina

Keep the following information in mind while searching for Harrisburg to South Carolina flight deals. Data was last updated April 24, 2025.

Most accurate provider

FlightHub
3 stars

Most trusted provider

eDreams
3 stars

Round-trip from

$98
(Gotogate)

One-way from

$65
(Mytrip)

Popular in

March

Cheapest in

June

Average price

$199
Provider with most accurate pricing for Harrisburg-Myrtle Beach Intl flight deals.
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Provider most trusted by Cheapflights users for Harrisburg-Myrtle Beach Intl flights.
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From Harrisburg to South Carolina
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One-way flight from Harrisburg to South Carolina
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Highest demand for flights based on searches. 16% potential increase in price ($50 potential increase over avg. RT price).
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Cheapest flight prices on average. 5% potential price decrease ($13 potential savings vs. average RT price).
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Average for round-trip flights in April 2025
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Find flight deals from Harrisburg to South Carolina

Cheapest flights from Harrisburg to South Carolina
Explore the most affordable flight options available from Harrisburg to South Carolina. Find the lowest fares from popular airlines and budget airlines, with prices last updated on April 24, 2025.

This Gotogate deal was found by Cheapflights users on 4/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Gotogate is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 7/134:36 pmMDT - MYR
Nonstop1h 31mAllegiant Air
Sat 7/196:57 pmMYR - MDT
Nonstop1h 33mAllegiant Air
Deal found 4/23$98
This American Airlines deal was found by Cheapflights users on 4/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/283:20 pmMDT - SAV
1 stop5h 42mAmerican Airlines
Thu 5/296:11 pmSAV - MDT
1 stop3h 56mAmerican Airlines
Deal found 4/22$199
This American Airlines deal was found by Cheapflights users on 4/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/295:00 amMDT - MYR
1 stop3h 30mAmerican Airlines
Tue 7/17:40 pmMYR - MDT
1 stop3h 49mAmerican Airlines
Deal found 4/23$199
This Mytrip deal was found by Cheapflights users on 4/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/16:27 pmMDT - CLT
1 stop12h 27mFrontier
Wed 5/2811:31 amCLT - MDT
1 stop23h 00mFrontier
Deal found 4/22$204
This Mytrip deal was found by Cheapflights users on 4/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 6/16:59 pmMDT - MYR
1 stop26h 06mMultiple Airlines
Sat 6/74:16 pmMYR - MDT
Nonstop1h 32mMultiple Airlines
Deal found 4/22$210
This Delta deal was found by Cheapflights users on 4/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/286:24 amMDT - SAV
1 stop4h 13mDelta
Wed 5/286:30 pmSAV - MDT
1 stop4h 13mDelta
Deal found 4/22$217
This United Airlines deal was found by Cheapflights users on 4/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/216:15 amMDT - GSP
1 stop3h 37mUnited Airlines
Wed 5/287:46 pmGSP - MDT
1 stop3h 44mUnited Airlines
Deal found 4/22$229
This Delta deal was found by Cheapflights users on 4/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 6/186:25 pmMDT - CAE
1 stop5h 32mDelta
Tue 6/241:43 pmCAE - MDT
1 stop3h 47mDelta
Deal found 4/22$229
This United Airlines deal was found by Cheapflights users on 4/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/106:30 amMDT - MYR
1 stop8h 12mUnited Airlines
Sat 9/132:42 pmMYR - MDT
1 stop4h 16mUnited Airlines
Deal found 4/22$229
This Delta deal was found by Cheapflights users on 4/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 6/34:50 pmMDT - GSP
2 stops7h 02mDelta
Tue 6/106:25 pmGSP - MDT
1 stop4h 35mDelta
Deal found 4/23$234
This Mytrip deal was found by Cheapflights users on 4/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 6/176:38 pmMDT - CLT
1 stop21h 45mMultiple Airlines
Wed 6/259:02 pmCLT - MDT
1 stop21h 01mMultiple Airlines
Deal found 4/21$243
This American Airlines deal was found by Cheapflights users on 4/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/217:58 pmMDT - CHS
1 stop4h 17mAmerican Airlines
Sun 5/255:07 amCHS - MDT
1 stop3h 56mAmerican Airlines
Deal found 4/23$249

Cheapflights Fare Finder

Customize your flight search to find flights from Harrisburg to South Carolina that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated April 24, 2025.
Use the filters below to find and compare flights from Harrisburg to South Carolina that are best for you.

Fly from

Harrisburg

Fly to

South Carolina

Route

Depart

Return

Price

HarrisburgMyrtle Beach

MDT - MYR

MDTMYR

Harrisburg

Sun 7/13

4:36 pm-6:07 pm

Nonstop1h 31m

Myrtle Beach Intl

Sat 7/19

6:57 pm-8:30 pm

Nonstop1h 33m

$98

HarrisburgSavannah

MDT - SAV

MDTSAV

Harrisburg

Wed 5/28

3:20 pm-9:02 pm

1 stop5h 42m

Savannah/Hilton Head

Thu 5/29

6:11 pm-10:07 pm

1 stop3h 56m

$199

HarrisburgMyrtle Beach

MDT - MYR

MDTMYR

Harrisburg

Sun 5/25

6:00 am-10:09 am

1 stop4h 09m

Myrtle Beach Intl

Thu 5/29

6:00 am-11:01 am

1 stop5h 01m

$199

HarrisburgCharlotte

MDT - CLT

MDTCLT

Harrisburg

Thu 5/1

6:27 pm-6:54 am

1 stop12h 27m

Charlotte Douglas

Wed 5/28

11:31 am-10:31 am

1 stop23h 00m

$204

HarrisburgSavannah

MDT - SAV

MDTSAV

Harrisburg

Wed 5/28

6:24 am-10:37 am

1 stop4h 13m

Savannah/Hilton Head

Wed 5/28

6:30 pm-10:43 pm

1 stop4h 13m

$217

HarrisburgMyrtle Beach

MDT - MYR

MDTMYR

Harrisburg

Sun 7/13

7:00 pm-10:54 pm

1 stop27h 54m

Myrtle Beach Intl

Sat 7/19

6:57 pm-8:30 pm

Nonstop1h 33m

$223

HarrisburgGreenville

MDT - GSP

MDTGSP

Harrisburg

Wed 5/21

6:15 am-9:52 am

1 stop3h 37m

Greenville

Wed 5/28

7:46 pm-11:30 pm

1 stop3h 44m

$229

HarrisburgColumbia

MDT - CAE

MDTCAE

Harrisburg

Wed 6/18

6:25 pm-11:57 pm

1 stop5h 32m

Columbia Metropolitan

Tue 6/24

1:43 pm-5:30 pm

1 stop3h 47m

$229

HarrisburgGreenville

MDT - GSP

MDTGSP

Harrisburg

Tue 6/3

4:50 pm-11:52 pm

2 stops7h 02m

Greenville

Tue 6/10

6:25 pm-11:00 pm

1 stop4h 35m

$234

HarrisburgCharlotte

MDT - CLT

MDTCLT

Harrisburg

Tue 6/17

6:38 pm-4:23 pm

1 stop21h 45m

Charlotte Douglas

Wed 6/25

9:02 pm-6:03 pm

1 stop21h 01m

$243

Flights are sorted by cheapest round-trip flights first.

Deals found on 4/23

Showing 1-10 of 49 results
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Best time to book a flight from Harrisburg to South Carolina

Have a flexible travel schedule? Discover the best time to fly to South Carolina from Harrisburg with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Harrisburg to South Carolina

What is the cheapest month to book a flight from Harrisburg to South Carolina?

Currently, August is the cheapest month in which you can book a flight from Harrisburg to South Carolina (average of $217). Flying from Harrisburg to South Carolina in March is currently the most expensive (average of $335). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from MDT to SC?

Find hourly flight availability from Harrisburg to South Carolina. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated April 24, 2025.

Regardless of the time of day you decide to fly, the ticket price will remain around the same. Book flights from Harrisburg to South Carolina as you normally would.

Rainfall in South Carolina by month

Plan your trip to South Carolina by taking into account the average rainfall totals by month.

In terms of precipitation, rainfall in South Carolina ranges from 3.0 - 6.5 inches per month. July is typically the wettest month, when rainfall can reach 6.5 in. November is typically the driest time to visit South Carolina when rainfall is around 3.0 in.

Temperature in South Carolina by month

Plan your trip to South Carolina by taking into account the average temperature totals by month.

If weather is an important factor for your trip to South Carolina, use this chart to help with planning. For those seeking warmer temperatures, July is the ideal time of year to visit, when temperatures reach an average of 78.8 F. Travelers looking to avoid the cold should look outside of January, when temperatures are typically at their lowest (around 44.6 F).

Reviews of airlines servicing South Carolina

Get insights into the airlines that provide service to South Carolina. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to South Carolina. Reviews last updated April 24, 2025.
To help decide which airline to fly from Harrisburg to South Carolina, see what other customers have to say about Delta, United Airlines and Allegiant Air. In addition to providing an overall rating, users have also rated airlines in terms of entertainment options, comfort, food, crew/service, and boarding process.
Delta
8.0
Very good
7,920 reviews

Boarding

8.2

Overall

8.0

Crew

8.5

Entertainment

7.9

Comfort

7.9

Food

7.3

Reviews

1 / 20
10.0
Excellent

Aaron,Oct 2024

TUS - LAX

Delta has consistently been the best U.S. airline for my travels and this flight was no exception
Delta
8.0
Very good
7,920 reviews
Delta
8.0
Very good
7,920 reviews

Boarding

8.2

Overall

8.0

Crew

8.5

Entertainment

7.9

Comfort

7.9

Food

7.3

Reviews

1 / 20
10.0
Excellent

Aaron,Oct 2024

TUS - LAX

Delta has consistently been the best U.S. airline for my travels and this flight was no exception
United Airlines
7.4
Good
8,685 reviews
Delta
8.0
Very good
7,920 reviews

Boarding

8.2

Overall

8.0

Crew

8.5

Entertainment

7.9

Comfort

7.9

Food

7.3

Reviews

1 / 20
10.0
Excellent

Aaron,Oct 2024

TUS - LAX

Delta has consistently been the best U.S. airline for my travels and this flight was no exception
Allegiant Air
7.3
Good
734 reviews
Delta
8.0
Very good
7,920 reviews

Boarding

8.2

Overall

8.0

Crew

8.5

Entertainment

7.9

Comfort

7.9

Food

7.3

Reviews

1 / 20
10.0
Excellent

Aaron,Oct 2024

TUS - LAX

Delta has consistently been the best U.S. airline for my travels and this flight was no exception
American Airlines
7.2
Good
10,000 reviews
Delta
8.0
Very good
7,920 reviews

Boarding

8.2

Overall

8.0

Crew

8.5

Entertainment

7.9

Comfort

7.9

Food

7.3

Reviews

1 / 20
10.0
Excellent

Aaron,Oct 2024

TUS - LAX

Delta has consistently been the best U.S. airline for my travels and this flight was no exception
Frontier
6.0
Okay
3,283 reviews
Delta
8.0
Very good
7,920 reviews

Boarding

8.2

Overall

8.0

Crew

8.5

Entertainment

7.9

Comfort

7.9

Food

7.3

Reviews

1 / 20
10.0
Excellent

Aaron,Oct 2024

TUS - LAX

Delta has consistently been the best U.S. airline for my travels and this flight was no exception

Related info for your journey

Find useful and relevant information for your journey from Harrisburg to South Carolina. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly from for flights from Harrisburg to South Carolina?

    If you book a flight to South Carolina from Harrisburg, you will be flying from Harrisburg, which is the city’s only airport. Harrisburg (MDT) is located 8.5 mi from the center of Harrisburg.

  • What are the cheapest airlines to fly from Harrisburg to South Carolina one-way?

    The cheapest airline one-way is Allegiant Air, with whom users have recently found tickets for as low as $65. However, be on the lookout for offers from Frontier and Delta, as they are both options that can get you from Harrisburg to South Carolina for a low price.

  • What are the most popular routes from Harrisburg to South Carolina?

    The most popular flight routes from Harrisburg to South Carolina are Harrisburg - Charlotte Douglas, Harrisburg - Charleston and Harrisburg - Myrtle Beach Intl.

  • Can I find deals for flights from Harrisburg to South Carolina that include hotel bookings?

    Yes. In addition to deals on Harrisburg to South Carolina flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Harrisburg to South Carolina?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Harrisburg to South Carolina.

  • Can I find deals for business class flights from Harrisburg to South Carolina?

    Yes. Cheapflights offers flight deals from Harrisburg to South Carolina by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Harrisburg to South Carolina?

    Currently, August is the cheapest month in which you can book a flight from Harrisburg to South Carolina (average of $217). Flying from Harrisburg to South Carolina in March is currently the most expensive (average of $335). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

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Alternative routes for Harrisburg to South Carolina

See prices for flight routes from nearby airports that may be better suited for you.
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Top 4 airlines flying from Harrisburg to South Carolina

Discover the top 4 airlines that operate flights from Harrisburg to South Carolina. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated April 24, 2025.
AirlineCheapestAverageFlexibilityOn-time
Allegiant AirCheapest$104Average$151FlexibilityNo cancel feeOn-time88%
DeltaCheapest$164Average$295FlexibilityNo cancel feeOn-timeN/A
American AirlinesCheapest$203Average$371FlexibilityNo cancel feeOn-time71%
United AirlinesCheapest$233Average$441FlexibilityNo cancel feeOn-time69%

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