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$66+ Cheap flights from Harrisburg (MDT) to South Carolina

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 3/4. Fares are subject to change and may not be available on all flights or dates of travel.
MDT — CHS
Feb 4 — Feb 111
Tue 2/4
Tue 2/11
1 adult, Economy
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Cheap flight deals from Harrisburg to South Carolina

Discover tips and strategies to find the most affordable flight options for your journey from Harrisburg (MDT) to South Carolina (USSC). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated January 30, 2025.

Most accurate provider

FlightHub
3 stars

Most trusted provider

FlightHub
3 stars

Round-trip from

$120
(Booking.com)

One-way from

$66
(Booking.com)

Popular in

March

Cheapest in

May

Average price

$408
Provider with most accurate pricing for Harrisburg-Myrtle Beach Intl flight deals.
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Provider most trusted by Cheapflights users for Harrisburg-Myrtle Beach Intl flights.
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From Harrisburg to South Carolina
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One-way flight from Harrisburg to South Carolina
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Highest demand for flights based on searches. 25% potential increase in price ($91 potential increase over avg. RT price).
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Cheapest flight prices on average. 7% potential price decrease ($20 potential savings vs. average RT price).
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Average for round-trip flights in January 2025
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Find flight deals from Harrisburg to South Carolina

Cheapest flights from Harrisburg to South Carolina
Explore the most affordable flight options available from Harrisburg to South Carolina. Find the lowest fares from popular airlines and budget airlines, with prices last updated on January 30, 2025.

This Booking.com deal was found by Cheapflights users on 1/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Booking.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 2/2411:59 amMDT - CLT
1 stop19h 09mFrontier
Wed 2/267:44 pmCLT - MDT
1 stop20h 56mFrontier
Deal found 1/29$120
This Cheapflightsfares deal was found by Cheapflights users on 1/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 6/54:34 pmMDT - MYR
Nonstop1h 31mAllegiant Air
Sun 6/86:55 pmMYR - MDT
Nonstop1h 32mAllegiant Air
Deal found 1/29$128
This Mytrip deal was found by Cheapflights users on 1/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 2/248:53 pmMDT - CLT
2 stops19h 20mMultiple Airlines
Wed 2/268:20 pmCLT - MDT
1 stop13h 58mMultiple Airlines
Deal found 1/29$219
This Delta deal was found by Cheapflights users on 1/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 2/186:14 amMDT - GSP
1 stop4h 55mDelta
Tue 2/255:22 pmGSP - MDT
1 stop4h 39mDelta
Deal found 1/29$223
This American Airlines deal was found by Cheapflights users on 1/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 2/265:00 amMDT - GSP
1 stop5h 03mAmerican Airlines
Sat 3/16:01 pmGSP - MDT
1 stop4h 01mAmerican Airlines
Deal found 1/29$229
This American Airlines deal was found by Cheapflights users on 1/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 2/265:00 amMDT - MYR
1 stop5h 37mAmerican Airlines
Wed 3/55:54 pmMYR - MDT
1 stop4h 08mAmerican Airlines
Deal found 1/29$229
This Mytrip deal was found by Cheapflights users on 1/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/151:10 pmMDT - MYR
Nonstop1h 28mMultiple Airlines
Sun 5/186:04 pmMYR - MDT
1 stop14h 42mMultiple Airlines
Deal found 1/29$245
This American Airlines deal was found by Cheapflights users on 1/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 3/87:26 pmMDT - CHS
1 stop3h 26mAmerican Airlines
Wed 3/125:40 amCHS - MDT
1 stop5h 52mAmerican Airlines
Deal found 1/30$249
This Delta deal was found by Cheapflights users on 1/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 3/11:50 pmMDT - SAV
1 stop6h 45mDelta
Mon 3/37:08 pmSAV - MDT
1 stop4h 34mDelta
Deal found 1/29$249
This American Airlines deal was found by Cheapflights users on 1/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 4/88:55 amMDT - SAV
2 stops5h 24mAmerican Airlines
Tue 4/157:47 amSAV - MDT
1 stop6h 45mAmerican Airlines
Deal found 1/28$254
This Delta deal was found by Cheapflights users on 1/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 3/116:18 pmMDT - CAE
1 stop5h 19mDelta
Sat 3/158:05 amCAE - MDT
1 stop4h 46mDelta
Deal found 1/29$264
This American Airlines deal was found by Cheapflights users on 1/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 2/278:28 amMDT - CLT
Nonstop1h 54mAmerican Airlines
Thu 2/271:03 pmCLT - MDT
1 stop9h 16mAmerican Airlines
Deal found 1/29$287

Find flights from Harrisburg to South Carolina within your budget

Customize your flight search to find flights from Harrisburg to South Carolina that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated January 30, 2025.

Fly from

Any airport

Fly to

Any airport

Route

Depart

Return

Price

HarrisburgCharlotte

MDT - CLT

MDTCLT

Harrisburg

Mon 2/24

11:59 am-7:08 am

1 stop19h 09m

Charlotte Douglas

Wed 2/26

7:44 pm-4:40 pm

1 stop20h 56m

$120

HarrisburgMyrtle Beach

MDT - MYR

MDTMYR

Harrisburg

Thu 6/5

4:34 pm-6:05 pm

Nonstop1h 31m

Myrtle Beach Intl

Sun 6/8

6:55 pm-8:27 pm

Nonstop1h 32m

$128

HarrisburgCharlotte

MDT - CLT

MDTCLT

Harrisburg

Mon 2/24

8:53 pm-4:13 pm

2 stops19h 20m

Charlotte Douglas

Wed 2/26

8:20 pm-10:18 am

1 stop13h 58m

$219

HarrisburgGreenville

MDT - GSP

MDTGSP

Harrisburg

Tue 2/18

6:14 am-11:09 am

1 stop4h 55m

Greenville

Tue 2/25

5:22 pm-10:01 pm

1 stop4h 39m

$223

HarrisburgGreenville

MDT - GSP

MDTGSP

Harrisburg

Wed 2/26

6:43 am-10:49 am

1 stop4h 06m

Greenville

Sat 3/1

3:55 pm-10:02 pm

1 stop6h 07m

$229

HarrisburgMyrtle Beach

MDT - MYR

MDTMYR

Harrisburg

Wed 2/26

5:00 am-10:37 am

1 stop5h 37m

Myrtle Beach Intl

Wed 3/5

5:54 pm-10:02 pm

1 stop4h 08m

$229

HarrisburgMyrtle Beach

MDT - MYR

MDTMYR

Harrisburg

Thu 5/15

1:10 pm-2:38 pm

Nonstop1h 28m

Myrtle Beach Intl

Sun 5/18

6:04 pm-8:46 am

1 stop14h 42m

$245

HarrisburgSavannah

MDT - SAV

MDTSAV

Harrisburg

Sat 3/1

1:50 pm-8:35 pm

1 stop6h 45m

Savannah/Hilton Head

Mon 3/3

7:08 pm-11:42 pm

1 stop4h 34m

$249

HarrisburgCharleston

MDT - CHS

MDTCHS

Harrisburg

Sat 3/8

7:26 pm-10:52 pm

1 stop3h 26m

Charleston

Wed 3/12

5:57 pm-9:55 pm

1 stop3h 58m

$249

HarrisburgSavannah

MDT - SAV

MDTSAV

Harrisburg

Tue 4/8

8:55 am-2:19 pm

2 stops5h 24m

Savannah/Hilton Head

Tue 4/15

7:47 am-2:32 pm

1 stop6h 45m

$254

Flights are sorted by cheapest round-trip flights first.

Deals found on 1/29

Showing 1-10 of 41 results
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Best time to book a flight from Harrisburg to South Carolina

Have a flexible travel schedule? Discover the best time to fly to South Carolina from Harrisburg with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Travel insights for flights from Harrisburg to South Carolina

Get recent, data-driven insights about flights from Harrisburg to South Carolina including ideal travel times, pricing trends, and more.

What is the cheapest month to book a flight from Harrisburg to South Carolina?

Currently, August is the cheapest month in which you can book a flight from Harrisburg to South Carolina (average of $217). Flying from Harrisburg to South Carolina in March is currently the most expensive (average of $335). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from MDT to SC?

Find hourly flight availability from Harrisburg to South Carolina. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated January 30, 2025.

Regardless of the time of day you decide to fly, the ticket price will remain around the same. Book flights from Harrisburg to South Carolina as you normally would.

Rainfall in South Carolina by month

Plan your trip to South Carolina by taking into account the average rainfall totals by month.

In terms of precipitation, rainfall in South Carolina ranges from 3.0 - 6.5 inches per month. July is typically the wettest month, when rainfall can reach 6.5 in. November is typically the driest time to visit South Carolina when rainfall is around 3.0 in.

Temperature in South Carolina by month

Plan your trip to South Carolina by taking into account the average temperature totals by month.

If weather is an important factor for your trip to South Carolina, use this chart to help with planning. For those seeking warmer temperatures, July is the ideal time of year to visit, when temperatures reach an average of 78.8 F. Travelers looking to avoid the cold should look outside of January, when temperatures are typically at their lowest (around 44.6 F).

Reviews of airlines servicing South Carolina

Get insights into the airlines that provide service to South Carolina. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to South Carolina. Reviews last updated January 30, 2025.
To help decide which airline to fly from Harrisburg to South Carolina, see what other customers have to say about Delta, United Airlines and Allegiant Air. In addition to providing an overall rating, users have also rated airlines in terms of entertainment options, comfort, food, crew/service, and boarding process.
Delta
8.0
Very good
8,454 reviews

Boarding

8.2

Entertainment

7.9

Food

7.3

Overall

8.0

Comfort

8.0

Crew

8.5

Reviews

1 / 20

10.0
Excellent

Aaron,Oct 2024

TUS - LAX

Delta has consistently been the best U.S. airline for my travels and this flight was no exception

Delta
8.0
Very good
8,454 reviews
Delta
8.0
Very good
8,454 reviews

Boarding

8.2

Entertainment

7.9

Food

7.3

Overall

8.0

Comfort

8.0

Crew

8.5

Reviews

1 / 20

10.0
Excellent

Aaron,Oct 2024

TUS - LAX

Delta has consistently been the best U.S. airline for my travels and this flight was no exception

United Airlines
7.4
Good
8,913 reviews
Delta
8.0
Very good
8,454 reviews

Boarding

8.2

Entertainment

7.9

Food

7.3

Overall

8.0

Comfort

8.0

Crew

8.5

Reviews

1 / 20

10.0
Excellent

Aaron,Oct 2024

TUS - LAX

Delta has consistently been the best U.S. airline for my travels and this flight was no exception

Allegiant Air
7.3
Good
790 reviews
Delta
8.0
Very good
8,454 reviews

Boarding

8.2

Entertainment

7.9

Food

7.3

Overall

8.0

Comfort

8.0

Crew

8.5

Reviews

1 / 20

10.0
Excellent

Aaron,Oct 2024

TUS - LAX

Delta has consistently been the best U.S. airline for my travels and this flight was no exception

American Airlines
7.2
Good
10,000 reviews
Delta
8.0
Very good
8,454 reviews

Boarding

8.2

Entertainment

7.9

Food

7.3

Overall

8.0

Comfort

8.0

Crew

8.5

Reviews

1 / 20

10.0
Excellent

Aaron,Oct 2024

TUS - LAX

Delta has consistently been the best U.S. airline for my travels and this flight was no exception

Frontier
6.0
Okay
3,424 reviews
Delta
8.0
Very good
8,454 reviews

Boarding

8.2

Entertainment

7.9

Food

7.3

Overall

8.0

Comfort

8.0

Crew

8.5

Reviews

1 / 20

10.0
Excellent

Aaron,Oct 2024

TUS - LAX

Delta has consistently been the best U.S. airline for my travels and this flight was no exception

Related info for your journey

Find useful and relevant information for your journey from Harrisburg to South Carolina. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly from for flights from Harrisburg to South Carolina?

    If you book a flight to South Carolina from Harrisburg, you will be flying from Harrisburg, which is the city’s only airport. Harrisburg (MDT) is located 8.5 mi from the center of Harrisburg.

  • What are the cheapest airlines to fly from Harrisburg to South Carolina one-way?

    The cheapest airline one-way is Frontier, with whom users have recently found tickets for as low as $66. However, be on the lookout for offers from Allegiant Air and American Airlines, as they are both options that can get you from Harrisburg to South Carolina for a low price.

  • What are the most popular routes from Harrisburg to South Carolina?

    The most popular flight routes from Harrisburg to South Carolina are Harrisburg - Charlotte Douglas, Harrisburg - Myrtle Beach Intl and Harrisburg - Charleston.

  • Can I find deals for flights from Harrisburg to South Carolina that include hotel bookings?

    Yes. In addition to deals on Harrisburg to South Carolina flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Harrisburg to South Carolina?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Harrisburg to South Carolina.

  • Can I find deals for business class flights from Harrisburg to South Carolina?

    Yes. Cheapflights offers flight deals from Harrisburg to South Carolina by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Harrisburg to South Carolina?

    Currently, August is the cheapest month in which you can book a flight from Harrisburg to South Carolina (average of $217). Flying from Harrisburg to South Carolina in March is currently the most expensive (average of $335). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

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Alternative routes for Harrisburg to South Carolina

See prices for flight routes from nearby airports that may be better suited for you.
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Top 4 airlines flying from Harrisburg to South Carolina

Discover the top 4 airlines that operate flights from Harrisburg to South Carolina. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated January 30, 2025.
AirlineCheapestAverageFlexibilityOn-time
Allegiant AirCheapest$106Average$153FlexibilityNo cancel feeOn-time88%
DeltaCheapest$152Average$299FlexibilityNo cancel feeOn-timeN/A
American AirlinesCheapest$203Average$392FlexibilityNo cancel feeOn-time71%
United AirlinesCheapest$248Average$418FlexibilityNo cancel feeOn-time69%
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