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South Carolina

$66+ Cheap flights from Harrisburg (MDT) to South Carolina

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 5/11. Fares are subject to change and may not be available on all flights or dates of travel.
MDT — CHS
Apr 8 — Apr 151
Tue 4/8
Tue 4/15
1 adult, Economy
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Cheap flight deals from Harrisburg to South Carolina

Keep the following information in mind while searching for Harrisburg to South Carolina flight deals. Data was last updated April 3, 2025.

Most accurate provider

FlightHub
3 stars

Most trusted provider

FlightHub
3 stars

Round-trip from

$108
(Booking.com)

One-way from

$66
(Booking.com)

Popular in

March

Cheapest in

September

Average price

$210
Provider with most accurate pricing for Harrisburg-Myrtle Beach Intl flight deals.
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Provider most trusted by Cheapflights users for Harrisburg-Myrtle Beach Intl flights.
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From Harrisburg to South Carolina
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One-way flight from Harrisburg to South Carolina
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Highest demand for flights based on searches. 17% potential increase in price ($55 potential increase over avg. RT price).
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Cheapest flight prices on average. 5% potential price decrease ($13 potential savings vs. average RT price).
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Average for round-trip flights in April 2025
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Find flight deals from Harrisburg to South Carolina

Cheapest flights from Harrisburg to South Carolina
Explore the most affordable flight options available from Harrisburg to South Carolina. Find the lowest fares from popular airlines and budget airlines, with prices last updated on April 3, 2025.

This Booking.com deal was found by Cheapflights users on 4/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Booking.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 6/224:34 pmMDT - MYR
Nonstop1h 31mAllegiant Air
Thu 6/266:55 pmMYR - MDT
Nonstop1h 32mAllegiant Air
Deal found 4/1$108
This Mytrip deal was found by Cheapflights users on 4/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 5/1111:35 amMDT - MYR
Nonstop1h 30mMultiple Airlines
Fri 5/166:00 amMYR - MDT
1 stop26h 25mMultiple Airlines
Deal found 4/2$175
This Delta deal was found by Cheapflights users on 4/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/246:24 amMDT - GSP
1 stop5h 22mDelta
Wed 5/286:33 pmGSP - MDT
1 stop4h 10mDelta
Deal found 4/2$199
This American Airlines deal was found by Cheapflights users on 4/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/295:00 amMDT - CHS
1 stop3h 24mAmerican Airlines
Tue 6/36:09 pmCHS - MDT
1 stop3h 58mAmerican Airlines
Deal found 4/2$224
This American Airlines deal was found by Cheapflights users on 4/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 7/41:26 pmMDT - SAV
1 stop4h 02mAmerican Airlines
Sat 7/125:00 amSAV - MDT
1 stop4h 47mAmerican Airlines
Deal found 4/2$224
This American Airlines deal was found by Cheapflights users on 4/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/155:00 amMDT - CAE
1 stop3h 34mAmerican Airlines
Mon 5/198:45 pmCAE - MDT
1 stop3h 10mAmerican Airlines
Deal found 4/2$229
This American Airlines deal was found by Cheapflights users on 4/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 5/185:00 amMDT - MYR
1 stop3h 30mAmerican Airlines
Sun 5/257:54 pmMYR - MDT
1 stop4h 01mAmerican Airlines
Deal found 4/2$229
This American Airlines deal was found by Cheapflights users on 4/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 4/182:57 pmMDT - GSP
1 stop5h 28mAmerican Airlines
Sun 4/205:28 amGSP - MDT
1 stop3h 26mAmerican Airlines
Deal found 4/2$239
This Delta deal was found by Cheapflights users on 4/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 4/226:19 pmMDT - CHS
1 stop5h 37mDelta
Tue 4/295:35 amCHS - MDT
2 stops10h 42mDelta
Deal found 4/1$254
This Delta deal was found by Cheapflights users on 4/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/45:00 pmMDT - SAV
2 stops6h 59mDelta
Sat 10/115:30 amSAV - MDT
2 stops6h 27mDelta
Deal found 4/1$259
This Mytrip deal was found by Cheapflights users on 4/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/95:06 pmMDT - CHS
1 stop15h 32mMultiple Airlines
Sun 5/116:00 amCHS - MDT
2 stops34h 16mMultiple Airlines
Deal found 4/2$271
This Booking.com deal was found by Cheapflights users on 4/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Booking.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/35:40 pmMDT - CLT
1 stop23h 37mFrontier
Sat 4/58:58 amCLT - MDT
1 stop7h 52mFrontier
Deal found 4/2$279

Cheapflights Fare Finder

Customize your flight search to find flights from Harrisburg to South Carolina that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated April 3, 2025.
Use the filters below to find and compare flights from Harrisburg to South Carolina that are best for you.

Fly from

Harrisburg

Fly to

South Carolina

Route

Depart

Return

Price

HarrisburgMyrtle Beach

MDT - MYR

MDTMYR

Harrisburg

Sun 6/22

4:34 pm-6:05 pm

Nonstop1h 31m

Myrtle Beach Intl

Thu 6/26

6:55 pm-8:27 pm

Nonstop1h 32m

$108

HarrisburgMyrtle Beach

MDT - MYR

MDTMYR

Harrisburg

Sun 5/11

11:35 am-1:05 pm

Nonstop1h 30m

Myrtle Beach Intl

Fri 5/16

6:00 am-8:25 am

1 stop26h 25m

$175

HarrisburgGreenville

MDT - GSP

MDTGSP

Harrisburg

Sat 5/24

6:24 am-11:46 am

1 stop5h 22m

Greenville

Wed 5/28

6:33 pm-10:43 pm

1 stop4h 10m

$199

HarrisburgCharleston

MDT - CHS

MDTCHS

Harrisburg

Thu 5/29

5:00 am-8:24 am

1 stop3h 24m

Charleston

Tue 6/3

6:09 pm-10:07 pm

1 stop3h 58m

$224

HarrisburgSavannah

MDT - SAV

MDTSAV

Harrisburg

Fri 7/4

1:26 pm-5:28 pm

1 stop4h 02m

Savannah/Hilton Head

Sat 7/12

5:00 am-9:47 am

1 stop4h 47m

$224

HarrisburgColumbia

MDT - CAE

MDTCAE

Harrisburg

Thu 5/15

5:00 am-8:34 am

1 stop3h 34m

Columbia Metropolitan

Mon 5/19

8:45 pm-11:55 pm

1 stop3h 10m

$229

HarrisburgMyrtle Beach

MDT - MYR

MDTMYR

Harrisburg

Sun 5/18

5:00 am-8:30 am

1 stop3h 30m

Myrtle Beach Intl

Sun 5/25

7:54 pm-11:55 pm

1 stop4h 01m

$229

HarrisburgGreenville

MDT - GSP

MDTGSP

Harrisburg

Fri 4/18

2:57 pm-8:25 pm

1 stop5h 28m

Greenville

Sun 4/20

5:28 am-8:54 am

1 stop3h 26m

$239

HarrisburgCharleston

MDT - CHS

MDTCHS

Harrisburg

Tue 4/22

6:19 pm-11:56 pm

1 stop5h 37m

Charleston

Tue 4/29

5:35 am-4:17 pm

2 stops10h 42m

$254

HarrisburgCharleston

MDT - CHS

MDTCHS

Harrisburg

Fri 5/9

5:06 pm-8:38 am

1 stop15h 32m

Charleston

Sun 5/11

6:00 am-4:16 pm

2 stops34h 16m

$271

Flights are sorted by cheapest round-trip flights first.

Deals found on 4/2

Showing 1-10 of 44 results
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Best time to book a flight from Harrisburg to South Carolina

Have a flexible travel schedule? Discover the best time to fly to South Carolina from Harrisburg with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Harrisburg to South Carolina

What is the cheapest month to book a flight from Harrisburg to South Carolina?

Currently, August is the cheapest month in which you can book a flight from Harrisburg to South Carolina (average of $217). Flying from Harrisburg to South Carolina in March is currently the most expensive (average of $335). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from MDT to SC?

Find hourly flight availability from Harrisburg to South Carolina. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated April 3, 2025.

Regardless of the time of day you decide to fly, the ticket price will remain around the same. Book flights from Harrisburg to South Carolina as you normally would.

Rainfall in South Carolina by month

Plan your trip to South Carolina by taking into account the average rainfall totals by month.

In terms of precipitation, rainfall in South Carolina ranges from 3.0 - 6.5 inches per month. July is typically the wettest month, when rainfall can reach 6.5 in. November is typically the driest time to visit South Carolina when rainfall is around 3.0 in.

Temperature in South Carolina by month

Plan your trip to South Carolina by taking into account the average temperature totals by month.

If weather is an important factor for your trip to South Carolina, use this chart to help with planning. For those seeking warmer temperatures, July is the ideal time of year to visit, when temperatures reach an average of 78.8 F. Travelers looking to avoid the cold should look outside of January, when temperatures are typically at their lowest (around 44.6 F).

Reviews of airlines servicing South Carolina

Get insights into the airlines that provide service to South Carolina. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to South Carolina. Reviews last updated April 3, 2025.
To help decide which airline to fly from Harrisburg to South Carolina, see what other customers have to say about Delta, United Airlines and Allegiant Air. In addition to providing an overall rating, users have also rated airlines in terms of entertainment options, comfort, food, crew/service, and boarding process.
Delta
8.0
Very good
7,897 reviews

Food

7.3

Overall

8.0

Comfort

7.9

Boarding

8.2

Crew

8.5

Entertainment

7.9

Reviews

1 / 20
10.0
Excellent

Aaron,Oct 2024

TUS - LAX

Delta has consistently been the best U.S. airline for my travels and this flight was no exception
Delta
8.0
Very good
7,897 reviews
Delta
8.0
Very good
7,897 reviews

Food

7.3

Overall

8.0

Comfort

7.9

Boarding

8.2

Crew

8.5

Entertainment

7.9

Reviews

1 / 20
10.0
Excellent

Aaron,Oct 2024

TUS - LAX

Delta has consistently been the best U.S. airline for my travels and this flight was no exception
United Airlines
7.4
Good
8,616 reviews
Delta
8.0
Very good
7,897 reviews

Food

7.3

Overall

8.0

Comfort

7.9

Boarding

8.2

Crew

8.5

Entertainment

7.9

Reviews

1 / 20
10.0
Excellent

Aaron,Oct 2024

TUS - LAX

Delta has consistently been the best U.S. airline for my travels and this flight was no exception
Allegiant Air
7.3
Good
732 reviews
Delta
8.0
Very good
7,897 reviews

Food

7.3

Overall

8.0

Comfort

7.9

Boarding

8.2

Crew

8.5

Entertainment

7.9

Reviews

1 / 20
10.0
Excellent

Aaron,Oct 2024

TUS - LAX

Delta has consistently been the best U.S. airline for my travels and this flight was no exception
American Airlines
7.2
Good
10,000 reviews
Delta
8.0
Very good
7,897 reviews

Food

7.3

Overall

8.0

Comfort

7.9

Boarding

8.2

Crew

8.5

Entertainment

7.9

Reviews

1 / 20
10.0
Excellent

Aaron,Oct 2024

TUS - LAX

Delta has consistently been the best U.S. airline for my travels and this flight was no exception
Frontier
6.0
Okay
3,277 reviews
Delta
8.0
Very good
7,897 reviews

Food

7.3

Overall

8.0

Comfort

7.9

Boarding

8.2

Crew

8.5

Entertainment

7.9

Reviews

1 / 20
10.0
Excellent

Aaron,Oct 2024

TUS - LAX

Delta has consistently been the best U.S. airline for my travels and this flight was no exception

Related info for your journey

Find useful and relevant information for your journey from Harrisburg to South Carolina. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly from for flights from Harrisburg to South Carolina?

    If you book a flight to South Carolina from Harrisburg, you will be flying from Harrisburg, which is the city’s only airport. Harrisburg (MDT) is located 8.5 mi from the center of Harrisburg.

  • What are the cheapest airlines to fly from Harrisburg to South Carolina one-way?

    The cheapest airline one-way is Allegiant Air, with whom users have recently found tickets for as low as $66. However, be on the lookout for offers from Frontier and Delta, as they are both options that can get you from Harrisburg to South Carolina for a low price.

  • What are the most popular routes from Harrisburg to South Carolina?

    The most popular flight routes from Harrisburg to South Carolina are Harrisburg - Charlotte Douglas, Harrisburg - Charleston and Harrisburg - Savannah/Hilton Head.

  • Can I find deals for flights from Harrisburg to South Carolina that include hotel bookings?

    Yes. In addition to deals on Harrisburg to South Carolina flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Harrisburg to South Carolina?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Harrisburg to South Carolina.

  • Can I find deals for business class flights from Harrisburg to South Carolina?

    Yes. Cheapflights offers flight deals from Harrisburg to South Carolina by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Harrisburg to South Carolina?

    Currently, August is the cheapest month in which you can book a flight from Harrisburg to South Carolina (average of $217). Flying from Harrisburg to South Carolina in March is currently the most expensive (average of $335). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

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Alternative routes for Harrisburg to South Carolina

See prices for flight routes from nearby airports that may be better suited for you.
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Top 4 airlines flying from Harrisburg to South Carolina

Discover the top 4 airlines that operate flights from Harrisburg to South Carolina. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated April 3, 2025.
AirlineCheapestAverageFlexibilityOn-time
Allegiant AirCheapest$105Average$151FlexibilityNo cancel feeOn-time88%
DeltaCheapest$164Average$295FlexibilityNo cancel feeOn-timeN/A
American AirlinesCheapest$203Average$372FlexibilityNo cancel feeOn-time71%
United AirlinesCheapest$228Average$463FlexibilityNo cancel feeOn-time69%

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