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$179+ Cheap flights from Gainesville (GNV) to South Carolina

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 5/20. Fares are subject to change and may not be available on all flights or dates of travel.
GNV — CHS
Apr 22 — Apr 291
Tue 4/22
Tue 4/29
1 adult, Economy
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Cheap flight deals from Gainesville to South Carolina

Keep the following information in mind while searching for Gainesville to South Carolina flight deals. Data was last updated April 17, 2025.

Most accurate provider

FlightHub
3 stars

Most trusted provider

eDreams
3 stars

Round-trip from

$310
(American Airlines)

One-way from

$179
(Delta)
Provider with most accurate pricing for Gainesville Regional-Myrtle Beach Intl flight deals.
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Provider most trusted by Cheapflights users for Gainesville Regional-Myrtle Beach Intl flights.
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From Gainesville Regional to South Carolina
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One-way flight from Gainesville Regional to South Carolina
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Find flight deals from Gainesville to South Carolina

Cheapest flights from Gainesville to South Carolina
Explore the most affordable flight options available from Gainesville to South Carolina. Find the lowest fares from popular airlines and budget airlines, with prices last updated on April 17, 2025.

This American Airlines deal was found by Cheapflights users on 4/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 6/76:30 amGNV - CLT
Nonstop1h 37mAmerican Airlines
Sun 6/811:45 amCLT - GNV
Nonstop1h 40mAmerican Airlines
Deal found 4/17$310
This Delta deal was found by Cheapflights users on 4/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 6/71:12 pmGNV - CLT
1 stop3h 17mDelta
Sun 6/86:52 amCLT - GNV
1 stop5h 33mDelta
Deal found 4/17$330
This Delta deal was found by Cheapflights users on 4/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/84:59 pmGNV - GSP
1 stop4h 22mDelta
Sat 11/152:25 pmGSP - GNV
1 stop3h 55mDelta
Deal found 4/17$367
This Delta deal was found by Cheapflights users on 4/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 9/1510:15 amGNV - MYR
1 stop3h 11mDelta
Fri 9/196:00 amMYR - GNV
1 stop3h 23mDelta
Deal found 4/16$367
This American Airlines deal was found by Cheapflights users on 4/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/86:39 amGNV - GSP
2 stops7h 18mAmerican Airlines
Sat 11/159:20 amGSP - GNV
1 stop5h 24mAmerican Airlines
Deal found 4/17$372
This American Airlines deal was found by Cheapflights users on 4/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 9/156:00 amGNV - MYR
2 stops7h 59mAmerican Airlines
Fri 9/198:55 pmMYR - GNV
1 stop3h 09mAmerican Airlines
Deal found 4/16$372

Cheapflights Fare Finder

Customize your flight search to find flights from Gainesville to South Carolina that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated April 17, 2025.
Use the filters below to find and compare flights from Gainesville to South Carolina that are best for you.

Fly from

Gainesville

Fly to

South Carolina

Route

Depart

Return

Price

GainesvilleCharlotte

GNV - CLT

GNVCLT

Gainesville Regional

Sat 6/7

6:30 am-8:07 am

Nonstop1h 37m

Charlotte Douglas

Sun 6/8

11:45 am-1:25 pm

Nonstop1h 40m

$310

GainesvilleCharlotte

GNV - CLT

GNVCLT

Gainesville Regional

Sat 6/7

1:12 pm-4:29 pm

1 stop3h 17m

Charlotte Douglas

Sun 6/8

6:52 am-12:25 pm

1 stop5h 33m

$330

GainesvilleMyrtle Beach

GNV - MYR

GNVMYR

Gainesville Regional

Mon 9/15

10:15 am-1:26 pm

1 stop3h 11m

Myrtle Beach Intl

Fri 9/19

6:00 am-9:23 am

1 stop3h 23m

$367

GainesvilleMyrtle Beach

GNV - MYR

GNVMYR

Gainesville Regional

Mon 9/15

6:00 am-1:59 pm

2 stops7h 59m

Myrtle Beach Intl

Fri 9/19

8:55 pm-12:04 am

1 stop3h 09m

$372

GainesvilleGreenville

GNV - GSP

GNVGSP

Gainesville Regional

Mon 4/28

6:00 am-9:53 am

1 stop3h 53m

Greenville

Fri 5/2

4:19 pm-10:53 pm

2 stops6h 34m

$602

GainesvilleGreenville

GNV - GSP

GNVGSP

Gainesville Regional

Mon 4/28

6:00 am-10:34 am

1 stop4h 34m

Greenville

Fri 5/2

7:23 pm-10:28 pm

1 stop3h 05m

$613

GainesvilleCharlotte

GNV - CLT

GNVCLT

Gainesville Regional

Tue 5/20

6:00 am-4:02 pm

2 stops10h 02m

$179

GainesvilleCharlotte

GNV - CLT

GNVCLT

Gainesville Regional

Tue 6/17

6:00 am-5:05 pm

2 stops11h 05m

$259

GainesvilleGreenville

GNV - GSP

GNVGSP

Gainesville Regional

Sun 4/27

6:00 am-9:53 am

1 stop3h 53m

$284

Flights are sorted by cheapest round-trip flights first.

Deals found on 4/16

Best time to book a flight from Gainesville to South Carolina

Have a flexible travel schedule? Discover the best time to fly to South Carolina from Gainesville with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Gainesville to South Carolina

What is the cheapest month to book a flight from Gainesville to South Carolina?

Currently, August is the cheapest month in which you can book a flight from Gainesville to South Carolina (average of $217). Flying from Gainesville to South Carolina in March is currently the most expensive (average of $335). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from GNV to SC?

Find hourly flight availability from Gainesville to South Carolina. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated April 17, 2025.

Regardless of the time of day you decide to fly, the ticket price will remain around the same. Book flights from Gainesville to South Carolina as you normally would.

Rainfall in South Carolina by month

Plan your trip to South Carolina by taking into account the average rainfall totals by month.

In terms of precipitation, rainfall in South Carolina ranges from 3.0 - 6.5 inches per month. July is typically the wettest month, when rainfall can reach 6.5 in. November is typically the driest time to visit South Carolina when rainfall is around 3.0 in.

Temperature in South Carolina by month

Plan your trip to South Carolina by taking into account the average temperature totals by month.

If weather is an important factor for your trip to South Carolina, use this chart to help with planning. For those seeking warmer temperatures, July is the ideal time of year to visit, when temperatures reach an average of 78.8 F. Travelers looking to avoid the cold should look outside of January, when temperatures are typically at their lowest (around 44.6 F).

Reviews of airlines servicing South Carolina

Get insights into the airlines that provide service to South Carolina. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to South Carolina. Reviews last updated April 17, 2025.
See what other customers who have flown with Delta and American Airlines from Gainesville to South Carolina have to say. You can also see how each airline compares in terms of entertainment options, comfort, food, crew/service, and boarding process.
Delta
8.0
Very good
7,917 reviews

Boarding

8.2

Crew

8.5

Food

7.3

Entertainment

7.9

Comfort

7.9

Overall

8.0

Reviews

1 / 20
2.0
Mediocre

Santiago,Apr 2024

MCO - ATL

When I was going to board, one of the staff members told me that I could not board with my passport bag because it was tree items and I would need to check a bag. This was so stupid ! The bag was small. So I had to put my things in my pockets, put the funny bag inside the other bag. Then go throw it. Then in the plane put everything back again in my funny bag.
Delta
8.0
Very good
7,917 reviews
Delta
8.0
Very good
7,917 reviews

Boarding

8.2

Crew

8.5

Food

7.3

Entertainment

7.9

Comfort

7.9

Overall

8.0

Reviews

1 / 20
2.0
Mediocre

Santiago,Apr 2024

MCO - ATL

When I was going to board, one of the staff members told me that I could not board with my passport bag because it was tree items and I would need to check a bag. This was so stupid ! The bag was small. So I had to put my things in my pockets, put the funny bag inside the other bag. Then go throw it. Then in the plane put everything back again in my funny bag.
American Airlines
7.2
Good
10,000 reviews
Delta
8.0
Very good
7,917 reviews

Boarding

8.2

Crew

8.5

Food

7.3

Entertainment

7.9

Comfort

7.9

Overall

8.0

Reviews

1 / 20
2.0
Mediocre

Santiago,Apr 2024

MCO - ATL

When I was going to board, one of the staff members told me that I could not board with my passport bag because it was tree items and I would need to check a bag. This was so stupid ! The bag was small. So I had to put my things in my pockets, put the funny bag inside the other bag. Then go throw it. Then in the plane put everything back again in my funny bag.

Related info for your journey

Find useful and relevant information for your journey from Gainesville to South Carolina. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly from for flights from Gainesville to South Carolina?

    If you book a flight to South Carolina from Gainesville, you will be flying from Gainesville Regional, which is the city’s only airport. Gainesville Regional (GNV) is located 4.2 mi from the center of Gainesville.

  • What are the most popular routes from Gainesville to South Carolina?

    Most travelers choose Gainesville Regional - Charlotte Douglas, Gainesville Regional - Greenville or Gainesville Regional - Myrtle Beach Intl when deciding on the best route from Gainesville to South Carolina.

  • Can I find deals for flights from Gainesville to South Carolina that include hotel bookings?

    Yes. In addition to deals on Gainesville to South Carolina flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Gainesville to South Carolina?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Gainesville to South Carolina.

  • Can I find deals for business class flights from Gainesville to South Carolina?

    Yes. Cheapflights offers flight deals from Gainesville to South Carolina by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Gainesville to South Carolina?

    Currently, August is the cheapest month in which you can book a flight from Gainesville to South Carolina (average of $217). Flying from Gainesville to South Carolina in March is currently the most expensive (average of $335). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

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Alternative routes for Gainesville to South Carolina

See prices for flight routes from nearby airports that may be better suited for you.
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Top 2 airlines flying from Gainesville to South Carolina

Discover the top 2 airlines that operate flights from Gainesville to South Carolina. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated April 17, 2025.
AirlineCheapestAverageFlexibilityOn-time
DeltaCheapest$280Average$404FlexibilityNo cancel feeOn-timeN/A
American AirlinesCheapest$289Average$390FlexibilityNo cancel feeOn-time71%

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