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$284+ Cheap flights from Gainesville (GNV) to South Carolina

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 4/3. Fares are subject to change and may not be available on all flights or dates of travel.
GNV — CHS
Apr 2 — Apr 91
Wed 4/2
Wed 4/9
1 adult, Economy
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Cheap flight deals from Gainesville to South Carolina

Keep the following information in mind while searching for Gainesville to South Carolina flight deals. Data was last updated March 28, 2025.

Most accurate provider

FlightHub
3 stars

Most trusted provider

FlightHub
3 stars

Round-trip from

$285
(Delta)

One-way from

$284
(Delta)
Provider with most accurate pricing for Gainesville Regional-Myrtle Beach Intl flight deals.
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Provider most trusted by Cheapflights users for Gainesville Regional-Myrtle Beach Intl flights.
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From Gainesville Regional to South Carolina
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One-way flight from Gainesville Regional to South Carolina
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Find flight deals from Gainesville to South Carolina

Cheapest flights from Gainesville to South Carolina
Explore the most affordable flight options available from Gainesville to South Carolina. Find the lowest fares from popular airlines and budget airlines, with prices last updated on March 28, 2025.

This Delta deal was found by Cheapflights users on 3/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 4/196:00 amGNV - MYR
1 stop4h 37mDelta
Sat 4/266:00 amMYR - GNV
1 stop3h 28mDelta
Deal found 3/27$285
This American Airlines deal was found by Cheapflights users on 3/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 6/119:16 amGNV - CLT
Nonstop1h 42mAmerican Airlines
Thu 6/267:15 amCLT - GNV
Nonstop1h 36mAmerican Airlines
Deal found 3/27$310
This Delta deal was found by Cheapflights users on 3/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 6/2110:08 amGNV - CLT
1 stop4h 54mDelta
Sun 6/2211:24 amCLT - GNV
1 stop3h 45mDelta
Deal found 3/27$330
This American Airlines deal was found by Cheapflights users on 3/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 4/193:20 pmGNV - MYR
1 stop3h 40mAmerican Airlines
Sat 4/262:42 pmMYR - GNV
2 stops8h 11mAmerican Airlines
Deal found 3/27$344
This Delta deal was found by Cheapflights users on 3/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 4/115:55 pmGNV - GSP
1 stop4h 28mDelta
Tue 4/155:46 amGSP - GNV
1 stop3h 42mDelta
Deal found 3/27$427
This American Airlines deal was found by Cheapflights users on 3/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 4/116:00 amGNV - GSP
1 stop3h 53mAmerican Airlines
Tue 4/152:33 pmGSP - GNV
2 stops8h 20mAmerican Airlines
Deal found 3/27$432

Cheapflights Fare Finder

Customize your flight search to find flights from Gainesville to South Carolina that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated March 28, 2025.
Use the filters below to find and compare flights from Gainesville to South Carolina that are best for you.

Fly from

Gainesville

Fly to

South Carolina

Route

Depart

Return

Price

GainesvilleMyrtle Beach

GNV - MYR

GNVMYR

Gainesville Regional

Sat 4/19

6:00 am-10:37 am

1 stop4h 37m

Myrtle Beach Intl

Sat 4/26

6:00 am-9:28 am

1 stop3h 28m

$285

GainesvilleCharlotte

GNV - CLT

GNVCLT

Gainesville Regional

Wed 6/11

9:16 am-10:58 am

Nonstop1h 42m

Charlotte Douglas

Thu 6/26

7:15 am-8:51 am

Nonstop1h 36m

$310

GainesvilleCharlotte

GNV - CLT

GNVCLT

Gainesville Regional

Sat 6/21

10:08 am-3:02 pm

1 stop4h 54m

Charlotte Douglas

Sun 6/22

11:24 am-3:09 pm

1 stop3h 45m

$330

GainesvilleMyrtle Beach

GNV - MYR

GNVMYR

Gainesville Regional

Sat 4/19

3:20 pm-7:00 pm

1 stop3h 40m

Myrtle Beach Intl

Sat 4/26

2:42 pm-10:53 pm

2 stops8h 11m

$344

GainesvilleGreenville

GNV - GSP

GNVGSP

Gainesville Regional

Fri 4/11

5:55 pm-10:23 pm

1 stop4h 28m

Greenville

Tue 4/15

5:46 am-9:28 am

1 stop3h 42m

$427

GainesvilleGreenville

GNV - GSP

GNVGSP

Gainesville Regional

Fri 4/11

6:00 am-9:53 am

1 stop3h 53m

Greenville

Tue 4/15

2:33 pm-10:53 pm

2 stops8h 20m

$432

GainesvilleMyrtle Beach

GNV - MYR

GNVMYR

Gainesville Regional

Thu 4/3

6:00 am-10:47 am

1 stop4h 47m

$284

GainesvilleMyrtle Beach

GNV - MYR

GNVMYR

Gainesville Regional

Thu 4/3

6:22 am-2:04 pm

2 stops7h 42m

$289

GainesvilleCharlotte

GNV - CLT

GNVCLT

Gainesville Regional

Wed 4/23

6:00 am-7:37 am

Nonstop1h 37m

$373

Flights are sorted by cheapest round-trip flights first.

Deals found on 3/27

Best time to book a flight from Gainesville to South Carolina

Have a flexible travel schedule? Discover the best time to fly to South Carolina from Gainesville with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Gainesville to South Carolina

What is the cheapest month to book a flight from Gainesville to South Carolina?

Currently, August is the cheapest month in which you can book a flight from Gainesville to South Carolina (average of $217). Flying from Gainesville to South Carolina in March is currently the most expensive (average of $335). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from GNV to SC?

Find hourly flight availability from Gainesville to South Carolina. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated March 28, 2025.

Regardless of the time of day you decide to fly, the ticket price will remain around the same. Book flights from Gainesville to South Carolina as you normally would.

Rainfall in South Carolina by month

Plan your trip to South Carolina by taking into account the average rainfall totals by month.

In terms of precipitation, rainfall in South Carolina ranges from 3.0 - 6.5 inches per month. July is typically the wettest month, when rainfall can reach 6.5 in. November is typically the driest time to visit South Carolina when rainfall is around 3.0 in.

Temperature in South Carolina by month

Plan your trip to South Carolina by taking into account the average temperature totals by month.

If weather is an important factor for your trip to South Carolina, use this chart to help with planning. For those seeking warmer temperatures, July is the ideal time of year to visit, when temperatures reach an average of 78.8 F. Travelers looking to avoid the cold should look outside of January, when temperatures are typically at their lowest (around 44.6 F).

Reviews of airlines servicing South Carolina

Get insights into the airlines that provide service to South Carolina. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to South Carolina. Reviews last updated March 28, 2025.
See what other customers who have flown with Delta and American Airlines from Gainesville to South Carolina have to say. You can also see how each airline compares in terms of entertainment options, comfort, food, crew/service, and boarding process.
Delta
8.0
Very good
7,897 reviews

Comfort

8.0

Crew

8.5

Food

7.3

Boarding

8.2

Entertainment

7.9

Overall

8.0

Reviews

1 / 20
2.0
Mediocre

Santiago,Apr 2024

MCO - ATL

When I was going to board, one of the staff members told me that I could not board with my passport bag because it was tree items and I would need to check a bag. This was so stupid ! The bag was small. So I had to put my things in my pockets, put the funny bag inside the other bag. Then go throw it. Then in the plane put everything back again in my funny bag.
Delta
8.0
Very good
7,897 reviews
Delta
8.0
Very good
7,897 reviews

Comfort

8.0

Crew

8.5

Food

7.3

Boarding

8.2

Entertainment

7.9

Overall

8.0

Reviews

1 / 20
2.0
Mediocre

Santiago,Apr 2024

MCO - ATL

When I was going to board, one of the staff members told me that I could not board with my passport bag because it was tree items and I would need to check a bag. This was so stupid ! The bag was small. So I had to put my things in my pockets, put the funny bag inside the other bag. Then go throw it. Then in the plane put everything back again in my funny bag.
American Airlines
7.2
Good
10,000 reviews
Delta
8.0
Very good
7,897 reviews

Comfort

8.0

Crew

8.5

Food

7.3

Boarding

8.2

Entertainment

7.9

Overall

8.0

Reviews

1 / 20
2.0
Mediocre

Santiago,Apr 2024

MCO - ATL

When I was going to board, one of the staff members told me that I could not board with my passport bag because it was tree items and I would need to check a bag. This was so stupid ! The bag was small. So I had to put my things in my pockets, put the funny bag inside the other bag. Then go throw it. Then in the plane put everything back again in my funny bag.

Related info for your journey

Find useful and relevant information for your journey from Gainesville to South Carolina. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly from for flights from Gainesville to South Carolina?

    If you book a flight to South Carolina from Gainesville, you will be flying from Gainesville Regional, which is the city’s only airport. Gainesville Regional (GNV) is located 4.2 mi from the center of Gainesville.

  • What are the most popular routes from Gainesville to South Carolina?

    Most travelers choose Gainesville Regional - Charlotte Douglas, Gainesville Regional - Greenville or Gainesville Regional - Myrtle Beach Intl when deciding on the best route from Gainesville to South Carolina.

  • Can I find deals for flights from Gainesville to South Carolina that include hotel bookings?

    Yes. In addition to deals on Gainesville to South Carolina flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Gainesville to South Carolina?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Gainesville to South Carolina.

  • Can I find deals for business class flights from Gainesville to South Carolina?

    Yes. Cheapflights offers flight deals from Gainesville to South Carolina by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Gainesville to South Carolina?

    Currently, August is the cheapest month in which you can book a flight from Gainesville to South Carolina (average of $217). Flying from Gainesville to South Carolina in March is currently the most expensive (average of $335). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

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Alternative routes for Gainesville to South Carolina

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Top 2 airlines flying from Gainesville to South Carolina

Discover the top 2 airlines that operate flights from Gainesville to South Carolina. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated March 28, 2025.
AirlineCheapestAverageFlexibilityOn-time
DeltaCheapest$280Average$404FlexibilityNo cancel feeOn-timeN/A
American AirlinesCheapest$289Average$366FlexibilityNo cancel feeOn-time71%
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