HomeSearch by dateVacation packagesHotelsFlight dealsCar rentalTravel tips & news
South Carolina

$45+ Cheap flights from Durham, NC to South Carolina

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 3/10. Fares are subject to change and may not be available on all flights or dates of travel.
RDU — CHS
Feb 26 — Mar 51
Wed 2/26
Wed 3/5
1 adult, Economy
We work with more than 300 partners to bring you better travel deals

Find cheap flights from Durham to South Carolina with Cheapflights

1. Tell us where you want to go
Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”
2. Select your favorite providers
We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.
3. Compare prices and book
Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.

Cheap flight deals from Durham to South Carolina

Keep the following information in mind while searching for Durham to South Carolina flight deals. Data was last updated February 21, 2025.

Most accurate provider

FlightHub
3 stars

Most trusted provider

FlightHub
3 stars

Round-trip from

$72
(Breeze Airways)

One-way from

$45
(Kiwi.com)

Popular in

December

Cheapest in

August

Average price

$235
Provider with most accurate pricing for Raleigh-Durham-Myrtle Beach Intl flight deals.
Search Deals
Provider most trusted by Cheapflights users for Raleigh-Durham-Myrtle Beach Intl flights.
Search Deals
From Durham to South Carolina
Search Deals
One-way flight from Durham to South Carolina
Search Deals
Highest demand for flights based on searches. 21% potential increase in price ($82 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 5% potential price decrease ($17 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in February 2025
Search Deals

Find flight deals from Durham to South Carolina

Cheapest flights from Durham to South Carolina
Explore the most affordable flight options available from Durham to South Carolina. Find the lowest fares from popular airlines and budget airlines, with prices last updated on February 21, 2025.

This Breeze Airways deal was found by Cheapflights users on 2/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Breeze Airways is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 3/312:17 pmRDU - CHS
1 stop4h 44mBreeze Airways
Mon 3/107:00 amCHS - RDU
1 stop4h 37mBreeze Airways
Deal found 2/20$72
This Mytrip deal was found by Cheapflights users on 2/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 3/712:17 pmRDU - CHS
1 stop4h 44mMultiple Airlines
Tue 3/112:59 pmCHS - RDU
2 stops20h 56mMultiple Airlines
Deal found 2/20$121
This Mytrip deal was found by Cheapflights users on 2/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/31:24 pmRDU - CLT
1 stop22h 46mSpirit Airlines
Thu 4/1010:30 amCLT - RDU
1 stop10h 23mSpirit Airlines
Deal found 2/19$127
This FlightHub deal was found by Cheapflights users on 2/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure FlightHub is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 3/2210:58 amRDU - MYR
1 stop6h 38mSpirit Airlines
Sat 3/293:43 pmMYR - RDU
1 stop5h 05mSpirit Airlines
Deal found 2/20$145
This Mytrip deal was found by Cheapflights users on 2/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 3/209:53 pmRDU - CLT
1 stop26h 39mMultiple Airlines
Thu 3/278:33 amCLT - RDU
1 stop14h 29mMultiple Airlines
Deal found 2/20$153
This eDestinos deal was found by Cheapflights users on 2/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure eDestinos is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 4/610:16 pmRDU - GSP
1 stop22h 12mMultiple Airlines
Sun 4/131:35 pmGSP - RDU
1 stop22h 02mMultiple Airlines
Deal found 2/20$183
This Mytrip deal was found by Cheapflights users on 2/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 3/712:17 pmRDU - MYR
3 stops29h 19mMultiple Airlines
Tue 3/116:41 pmMYR - RDU
1 stop25h 48mMultiple Airlines
Deal found 2/20$184
This Southwest deal was found by Cheapflights users on 2/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 3/105:45 pmRDU - SAV
1 stop4h 20mSouthwest
Wed 3/128:20 amSAV - RDU
1 stop6h 00mSouthwest
Deal found 2/20$217
This Delta deal was found by Cheapflights users on 2/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 4/85:20 amRDU - CHS
1 stop6h 01mDelta
Fri 4/118:04 pmCHS - RDU
1 stop3h 55mDelta
Deal found 2/20$232
This American Airlines deal was found by Cheapflights users on 2/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 4/186:20 pmRDU - SAV
1 stop3h 41mAmerican Airlines
Mon 4/218:33 pmSAV - RDU
1 stop3h 25mAmerican Airlines
Deal found 2/20$262
This Southwest deal was found by Cheapflights users on 2/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 3/65:30 amRDU - GSP
1 stop5h 35mSouthwest
Sat 3/87:05 pmGSP - RDU
1 stop4h 00mSouthwest
Deal found 2/20$262
This American Airlines deal was found by Cheapflights users on 2/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 4/47:23 pmRDU - MYR
1 stop4h 21mAmerican Airlines
Wed 4/92:42 pmMYR - RDU
1 stop2h 48mAmerican Airlines
Deal found 2/20$266

Find flights from Durham to South Carolina within your budget

Customize your flight search to find flights from Durham to South Carolina that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated February 21, 2025.

Fly from

Durham

Fly to

South Carolina

Route

Depart

Return

Price

RaleighCharleston

RDU - CHS

RDUCHS

Raleigh-Durham

Mon 3/3

12:17 pm-5:01 pm

1 stop4h 44m

Charleston

Mon 3/10

7:00 am-11:37 am

1 stop4h 37m

$72

RaleighCharlotte

RDU - CLT

RDUCLT

Raleigh-Durham

Mon 4/7

10:26 pm-8:07 pm

1 stop21h 41m

Charlotte Douglas

Mon 4/14

9:23 pm-7:58 am

1 stop10h 35m

$113

RaleighCharleston

RDU - CHS

RDUCHS

Raleigh-Durham

Fri 3/7

12:17 pm-5:01 pm

1 stop4h 44m

Charleston

Tue 3/11

2:59 pm-11:55 am

2 stops20h 56m

$121

RaleighCharlotte

RDU - CLT

RDUCLT

Raleigh-Durham

Thu 4/3

1:24 pm-12:10 pm

1 stop22h 46m

Charlotte Douglas

Thu 4/10

10:30 am-8:53 pm

1 stop10h 23m

$127

RaleighMyrtle Beach

RDU - MYR

RDUMYR

Raleigh-Durham

Sat 3/22

10:58 am-5:36 pm

1 stop6h 38m

Myrtle Beach Intl

Sat 3/29

3:43 pm-8:48 pm

1 stop5h 05m

$145

RaleighCharlotte

RDU - CLT

RDUCLT

Raleigh-Durham

Thu 3/20

9:53 pm-12:32 am

1 stop26h 39m

Charlotte Douglas

Thu 3/27

8:33 am-11:02 pm

1 stop14h 29m

$153

RaleighGreenville

RDU - GSP

RDUGSP

Raleigh-Durham

Sun 4/6

10:16 pm-8:28 pm

1 stop22h 12m

Greenville

Sun 4/13

1:35 pm-11:37 am

1 stop22h 02m

$183

RaleighMyrtle Beach

RDU - MYR

RDUMYR

Raleigh-Durham

Fri 3/7

12:17 pm-5:36 pm

3 stops29h 19m

Myrtle Beach Intl

Tue 3/11

6:41 pm-8:29 pm

1 stop25h 48m

$184

RaleighSavannah

RDU - SAV

RDUSAV

Raleigh-Durham

Mon 3/10

5:45 pm-10:05 pm

1 stop4h 20m

Savannah/Hilton Head

Wed 3/12

8:20 am-2:20 pm

1 stop6h 00m

$217

RaleighCharleston

RDU - CHS

RDUCHS

Raleigh-Durham

Tue 4/8

5:20 am-11:21 am

1 stop6h 01m

Charleston

Fri 4/11

8:04 pm-11:59 pm

1 stop3h 55m

$232

Flights are sorted by cheapest round-trip flights first.

Deals found on 2/19

Showing 1-10 of 57 results
1
2
3
...
6

Best time to book a flight from Durham to South Carolina

Have a flexible travel schedule? Discover the best time to fly to South Carolina from Durham with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Travel insights for flights from Durham to South Carolina

Get recent, data-driven insights about flights from Durham to South Carolina including ideal travel times, pricing trends, and more.

What is the cheapest month to book a flight from Durham to South Carolina?

Currently, August is the cheapest month in which you can book a flight from Durham to South Carolina (average of $217). Flying from Durham to South Carolina in March is currently the most expensive (average of $335). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from DU8 to SC?

Find hourly flight availability from Durham to South Carolina. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated February 21, 2025.

When flying from Durham to South Carolina, the time of day you decide to fly out makes little to no difference towards the overall price you’ll pay on tickets.

Rainfall in South Carolina by month

Plan your trip to South Carolina by taking into account the average rainfall totals by month.

In terms of precipitation, rainfall in South Carolina ranges from 3.0 - 6.5 inches per month. July is typically the wettest month, when rainfall can reach 6.5 in. November is typically the driest time to visit South Carolina when rainfall is around 3.0 in.

Temperature in South Carolina by month

Plan your trip to South Carolina by taking into account the average temperature totals by month.

If weather is an important factor for your trip to South Carolina, use this chart to help with planning. For those seeking warmer temperatures, July is the ideal time of year to visit, when temperatures reach an average of 78.8 F. Travelers looking to avoid the cold should look outside of January, when temperatures are typically at their lowest (around 44.6 F).

Reviews of airlines servicing South Carolina

Get insights into the airlines that provide service to South Carolina. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to South Carolina. Reviews last updated February 21, 2025.
See what other customers who have flown with Southwest, Breeze Airways and Delta from Durham to South Carolina have to say. You can also see how each airline compares in terms of entertainment options, comfort, food, crew/service, and boarding process.
Southwest
8.1
Very good
4,401 reviews

Entertainment

7.6

Food

7.1

Crew

8.7

Overall

8.1

Comfort

8.1

Boarding

8.2

Reviews

1 / 20

2.0
Mediocre

Anonymous,Feb 2025

MCO - STL

Cancelled at last minute, SWA unable to assist in formulating alternate plans. Wound up renting a car and driving 13 hours to beat bad weather forecast at home. Not SWA’s fault that there was significant bad weather across the country.

Southwest
8.1
Very good
4,401 reviews
Southwest
8.1
Very good
4,401 reviews

Entertainment

7.6

Food

7.1

Crew

8.7

Overall

8.1

Comfort

8.1

Boarding

8.2

Reviews

1 / 20

2.0
Mediocre

Anonymous,Feb 2025

MCO - STL

Cancelled at last minute, SWA unable to assist in formulating alternate plans. Wound up renting a car and driving 13 hours to beat bad weather forecast at home. Not SWA’s fault that there was significant bad weather across the country.

Breeze Airways
8.1
Very good
150 reviews
Southwest
8.1
Very good
4,401 reviews

Entertainment

7.6

Food

7.1

Crew

8.7

Overall

8.1

Comfort

8.1

Boarding

8.2

Reviews

1 / 20

2.0
Mediocre

Anonymous,Feb 2025

MCO - STL

Cancelled at last minute, SWA unable to assist in formulating alternate plans. Wound up renting a car and driving 13 hours to beat bad weather forecast at home. Not SWA’s fault that there was significant bad weather across the country.

Delta
8.0
Very good
8,213 reviews
Southwest
8.1
Very good
4,401 reviews

Entertainment

7.6

Food

7.1

Crew

8.7

Overall

8.1

Comfort

8.1

Boarding

8.2

Reviews

1 / 20

2.0
Mediocre

Anonymous,Feb 2025

MCO - STL

Cancelled at last minute, SWA unable to assist in formulating alternate plans. Wound up renting a car and driving 13 hours to beat bad weather forecast at home. Not SWA’s fault that there was significant bad weather across the country.

JetBlue
7.4
Good
3,069 reviews
Southwest
8.1
Very good
4,401 reviews

Entertainment

7.6

Food

7.1

Crew

8.7

Overall

8.1

Comfort

8.1

Boarding

8.2

Reviews

1 / 20

2.0
Mediocre

Anonymous,Feb 2025

MCO - STL

Cancelled at last minute, SWA unable to assist in formulating alternate plans. Wound up renting a car and driving 13 hours to beat bad weather forecast at home. Not SWA’s fault that there was significant bad weather across the country.

United Airlines
7.4
Good
8,759 reviews
Southwest
8.1
Very good
4,401 reviews

Entertainment

7.6

Food

7.1

Crew

8.7

Overall

8.1

Comfort

8.1

Boarding

8.2

Reviews

1 / 20

2.0
Mediocre

Anonymous,Feb 2025

MCO - STL

Cancelled at last minute, SWA unable to assist in formulating alternate plans. Wound up renting a car and driving 13 hours to beat bad weather forecast at home. Not SWA’s fault that there was significant bad weather across the country.

Related info for your journey

Find useful and relevant information for your journey from Durham to South Carolina. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What are the cheapest airlines to fly from Durham to South Carolina one-way?

    For one-way options, check prices for Breeze Airways. According to our data, you can fly for as low as $45. Users have also found prices from $61 and $96 on Spirit Airlines and JetBlue, respectively.

  • What are the most popular routes from Durham to South Carolina?

    When deciding which route to take from Durham to South Carolina consider Raleigh-Durham - Charlotte Douglas, Raleigh-Durham - Charleston or Raleigh-Durham - Savannah/Hilton Head as they are the most popular.

  • What are the cheapest flights from Durham to South Carolina?

    Looking for the cheapest flight from Durham to South Carolina? While on average our users pay $51, our data indicates the cheapest price to be $47. The most popular route (Raleigh-Durham - Charlotte Douglas), is priced around $112.

  • Can I find deals for flights from Durham to South Carolina that include hotel bookings?

    Yes. In addition to deals on Durham to South Carolina flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Durham to South Carolina?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Durham to South Carolina.

  • Can I find deals for business class flights from Durham to South Carolina?

    Yes. Cheapflights offers flight deals from Durham to South Carolina by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Durham to South Carolina?

    Currently, August is the cheapest month in which you can book a flight from Durham to South Carolina (average of $217). Flying from Durham to South Carolina in March is currently the most expensive (average of $335). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Browse thousands of different options on Cheapflights for your next trip

Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.

Alternative routes for Durham to South Carolina

See prices for flight routes from nearby airports that may be better suited for you.
Charlotte to John F Kennedy Intl flights
Raleigh to John F Kennedy Intl flights
Raleigh to LaGuardia flights
Raleigh to Las Vegas flights
Raleigh to Seattle flights
Charlotte to Las Vegas flights
Raleigh to Newark flights
Charlotte to Denver flights
Charlotte to LaGuardia flights
Raleigh to O'Hare Intl flights
Raleigh to Orlando flights
Raleigh to Miami flights
Raleigh to Denver flights
Raleigh to Fort Lauderdale flights
Charlotte to Boston flights
Charlotte to Hobby flights
Charlotte to O'Hare Intl flights
Raleigh to Los Angeles flights
Charlotte to Newark flights
Charlotte to Fort Lauderdale flights
Raleigh to Boston flights
Raleigh to Hobby flights
Charlotte to Dulles Intl flights
Raleigh to Dallas/Fort Worth flights
Charlotte to George Bush Intcntl flights
Charlotte to Orlando flights
Charlotte to Miami flights
Charlotte to Dallas/Fort Worth flights
Raleigh to San Francisco flights
Raleigh to Atlanta flights
Charlotte to Seattle flights
Raleigh to Tampa flights
Raleigh to New Orleans flights
Raleigh to Sky Harbor Intl flights
Raleigh to George Bush Intcntl flights
Charlotte to Sky Harbor Intl flights
Raleigh to Nashville flights
Raleigh to Austin flights
Raleigh to Midway flights
Charlotte to Los Angeles flights
Norfolk to Hobby flights
Charlotte to Baltimore flights
Charlotte to Minneapolis flights
Raleigh to Dulles Intl flights
Charlotte to Nashville flights
Charlotte to Salt Lake City flights
Charlotte to Love Field flights
Raleigh to Salt Lake City flights
Charlotte to San Francisco flights
Charlotte to New Orleans flights

Top 4 airlines flying from Durham to South Carolina

Discover the top 4 airlines that operate flights from Durham to South Carolina. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated February 21, 2025.
AirlineCheapestAverageFlexibilityOn-time
Breeze AirwaysCheapest$87Average$165FlexibilityNo cancel feeOn-timeN/A
Spirit AirlinesCheapest$89Average$130FlexibilityNo cancel feeOn-time65%
DeltaCheapest$158Average$490FlexibilityNo cancel feeOn-timeN/A
American AirlinesCheapest$228Average$442FlexibilityNo cancel feeOn-time71%
100% Free
Cheapflights is completely free to use, so you can start saving the moment you arrive.
Book with Flexibility
Our users can plan ahead with confidence and find flights with no change fees
Travel Smart
Millions of people come to us for their flight needs every year. We help make travel planning easy by providing useful insights and data-driven graphs that can inform your decisions.