South Carolina

$48+ Cheap flights from Durham, NC to South Carolina

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 4/28. Fares are subject to change and may not be available on all flights or dates of travel.
RDU — CHS
Apr 22 — Apr 291
We work with more than 300 partners to bring you better travel deals

Find cheap flights from Durham to South Carolina with Cheapflights

1. Tell us where you want to go

Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”

2. Select your favorite providers

We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.

3. Compare prices and book

Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.

Cheap flight deals from Durham to South Carolina

Keep the following information in mind while searching for Durham to South Carolina flight deals. Data was last updated April 17, 2025.

Most accurate provider

FlightHub
3 stars

Most trusted provider

eDreams
3 stars

Round-trip from

$178
(Mytrip)

One-way from

$48
(Breeze Airways)

Popular in

March

Cheapest in

August

Average price

$517
Provider with most accurate pricing for Raleigh-Durham-Myrtle Beach Intl flight deals.
Provider most trusted by Cheapflights users for Raleigh-Durham-Myrtle Beach Intl flights.
From Durham to South Carolina
One-way flight from Durham to South Carolina
Highest demand for flights based on searches. 17% potential increase in price ($74 potential increase over avg. RT price).
Cheapest flight prices on average. 4% potential price decrease ($18 potential savings vs. average RT price).
Average for round-trip flights in April 2025

Find flight deals from Durham to South Carolina

Cheapest flights from Durham to South Carolina
Explore the most affordable flight options available from Durham to South Carolina. Find the lowest fares from popular airlines and budget airlines, with prices last updated on April 17, 2025.

This Breeze Airways deal was found by Cheapflights users on 4/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Breeze Airways is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 4/2512:17 pmRDU - CHS
1 stop4h 44mBreeze Airways
Mon 4/287:00 amCHS - RDU
1 stop4h 37mBreeze Airways
Deal found 4/16$125
This Mytrip deal was found by Cheapflights users on 4/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 5/511:45 amRDU - CHS
1 stop21h 35mSpirit Airlines
Sat 5/109:43 amCHS - RDU
2 stops22h 12mSpirit Airlines
Deal found 4/16$162
This Mytrip deal was found by Cheapflights users on 4/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 6/13:55 pmRDU - CLT
1 stop24h 52mSpirit Airlines
Sun 6/89:02 pmCLT - RDU
1 stop12h 10mSpirit Airlines
Deal found 4/17$225
This American Airlines deal was found by Cheapflights users on 4/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/102:50 pmRDU - GSP
1 stop5h 12mAmerican Airlines
Sun 5/116:26 amGSP - RDU
1 stop4h 02mAmerican Airlines
Deal found 4/16$228
This Delta deal was found by Cheapflights users on 4/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/245:20 pmRDU - SAV
1 stop4h 04mDelta
Sun 5/258:30 amSAV - RDU
1 stop4h 03mDelta
Deal found 4/17$229
This American Airlines deal was found by Cheapflights users on 4/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/144:20 pmRDU - MYR
1 stop2h 52mAmerican Airlines
Wed 5/215:00 amMYR - RDU
1 stop5h 28mAmerican Airlines
Deal found 4/16$229
This Delta deal was found by Cheapflights users on 4/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/145:21 pmRDU - GSP
1 stop4h 22mDelta
Wed 5/216:30 amGSP - RDU
1 stop4h 48mDelta
Deal found 4/16$229
This Southwest deal was found by Cheapflights users on 4/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/286:30 amRDU - GSP
1 stop3h 50mSouthwest
Sat 5/316:35 pmGSP - RDU
1 stop4h 25mSouthwest
Deal found 4/17$233
This Delta deal was found by Cheapflights users on 4/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/246:58 pmRDU - CHS
1 stop4h 46mDelta
Sat 5/315:35 amCHS - RDU
1 stop4h 19mDelta
Deal found 4/16$237
This Mytrip deal was found by Cheapflights users on 4/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/93:55 pmRDU - MYR
1 stop24h 49mMultiple Airlines
Tue 5/131:45 pmMYR - RDU
1 stop19h 07mMultiple Airlines
Deal found 4/16$241
This JetBlue deal was found by Cheapflights users on 4/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure JetBlue is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/149:52 amRDU - CHS
1 stop8h 09mJetBlue
Wed 5/2110:57 amCHS - RDU
1 stop4h 48mJetBlue
Deal found 4/15$242
This Mytrip deal was found by Cheapflights users on 4/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/93:55 pmRDU - MYR
1 stop24h 49mSpirit Airlines
Tue 5/135:32 pmMYR - RDU
3 stops38h 23mSpirit Airlines
Deal found 4/16$257

Cheapflights Fare Finder

Customize your flight search to find flights from Durham to South Carolina that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated April 17, 2025.
Use the filters below to find and compare flights from Durham to South Carolina that are best for you.

Fly from

Durham

Fly to

South Carolina

Route

Depart

Return

Price

RaleighCharleston

RDU - CHS

RDUCHS

Raleigh-Durham

Thu 5/1

11:29 am-9:36 am

1 stop22h 07m

Charleston

Sat 5/3

7:15 pm-10:34 am

1 stop15h 19m

$197

RaleighCharlotte

RDU - CLT

RDUCLT

Raleigh-Durham

Sun 6/1

3:55 pm-4:47 pm

1 stop24h 52m

Charlotte Douglas

Sun 6/8

9:02 pm-9:12 am

1 stop12h 10m

$225

RaleighGreenville

RDU - GSP

RDUGSP

Raleigh-Durham

Sat 5/10

2:50 pm-8:02 pm

1 stop5h 12m

Greenville

Sun 5/11

6:26 am-10:28 am

1 stop4h 02m

$228

RaleighSavannah

RDU - SAV

RDUSAV

Raleigh-Durham

Sat 5/24

3:26 pm-7:16 pm

1 stop3h 50m

Savannah/Hilton Head

Tue 5/27

4:51 pm-8:53 pm

1 stop4h 02m

$229

RaleighGreenville

RDU - GSP

RDUGSP

Raleigh-Durham

Wed 5/14

5:21 pm-9:43 pm

1 stop4h 22m

Greenville

Wed 5/21

6:30 am-11:18 am

1 stop4h 48m

$229

RaleighGreenville

RDU - GSP

RDUGSP

Raleigh-Durham

Wed 5/28

6:30 am-10:20 am

1 stop3h 50m

Greenville

Sat 5/31

6:35 pm-11:00 pm

1 stop4h 25m

$233

RaleighCharleston

RDU - CHS

RDUCHS

Raleigh-Durham

Sat 5/24

3:26 pm-8:28 pm

1 stop5h 02m

Charleston

Sun 5/25

8:00 am-2:20 pm

1 stop6h 20m

$237

RaleighMyrtle Beach

RDU - MYR

RDUMYR

Raleigh-Durham

Thu 5/1

11:29 am-8:54 pm

1 stop9h 25m

Myrtle Beach Intl

Sun 5/4

9:59 pm-10:40 am

1 stop12h 41m

$241

RaleighMyrtle Beach

RDU - MYR

RDUMYR

Raleigh-Durham

Sat 5/17

2:50 pm-7:12 pm

1 stop4h 22m

Myrtle Beach Intl

Sat 5/24

6:35 pm-11:58 pm

1 stop5h 23m

$249

RaleighSavannah

RDU - SAV

RDUSAV

Raleigh-Durham

Wed 6/4

6:30 am-10:35 am

1 stop4h 05m

Savannah/Hilton Head

Wed 6/11

7:25 am-4:05 pm

2 stops8h 40m

$260

Flights are sorted by cheapest round-trip flights first.

Deals found on 4/17

Showing 1-10 of 60 results
1
2
3
...
6

Best time to book a flight from Durham to South Carolina

Have a flexible travel schedule? Discover the best time to fly to South Carolina from Durham with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Durham to South Carolina

What is the cheapest month to book a flight from Durham to South Carolina?

Currently, August is the cheapest month in which you can book a flight from Durham to South Carolina (average of $217). Flying from Durham to South Carolina in March is currently the most expensive (average of $335). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from DU8 to SC?

Find hourly flight availability from Durham to South Carolina. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated April 17, 2025.

When flying from Durham to South Carolina, the time of day you decide to fly out makes little to no difference towards the overall price you’ll pay on tickets.

Rainfall in South Carolina by month

Plan your trip to South Carolina by taking into account the average rainfall totals by month.

In terms of precipitation, rainfall in South Carolina ranges from 3.0 - 6.5 inches per month. July is typically the wettest month, when rainfall can reach 6.5 in. November is typically the driest time to visit South Carolina when rainfall is around 3.0 in.

Temperature in South Carolina by month

Plan your trip to South Carolina by taking into account the average temperature totals by month.

If weather is an important factor for your trip to South Carolina, use this chart to help with planning. For those seeking warmer temperatures, July is the ideal time of year to visit, when temperatures reach an average of 78.8 F. Travelers looking to avoid the cold should look outside of January, when temperatures are typically at their lowest (around 44.6 F).

Reviews of airlines servicing South Carolina

Get insights into the airlines that provide service to South Carolina. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to South Carolina. Reviews last updated April 17, 2025.
See what other customers who have flown with Breeze Airways, Southwest and Delta from Durham to South Carolina have to say. You can also see how each airline compares in terms of entertainment options, comfort, food, crew/service, and boarding process.

Crew

8.8

Boarding

8.3

Overall

8.1

Entertainment

6.6

Food

6.7

Comfort

8.2

Reviews

1 / 11
10.0
Excellent

Dena,Dec 2024

LAS - BDL

It was comfortable and the crew was great! A few free snacks offered would be nice!

Crew

8.8

Boarding

8.3

Overall

8.1

Entertainment

6.6

Food

6.7

Comfort

8.2

Reviews

1 / 11
10.0
Excellent

Dena,Dec 2024

LAS - BDL

It was comfortable and the crew was great! A few free snacks offered would be nice!

Crew

8.8

Boarding

8.3

Overall

8.1

Entertainment

6.6

Food

6.7

Comfort

8.2

Reviews

1 / 11
10.0
Excellent

Dena,Dec 2024

LAS - BDL

It was comfortable and the crew was great! A few free snacks offered would be nice!
8.0
Very good

Crew

8.8

Boarding

8.3

Overall

8.1

Entertainment

6.6

Food

6.7

Comfort

8.2

Reviews

1 / 11
10.0
Excellent

Dena,Dec 2024

LAS - BDL

It was comfortable and the crew was great! A few free snacks offered would be nice!
Avelo Airlines
7.5
Good

Crew

8.8

Boarding

8.3

Overall

8.1

Entertainment

6.6

Food

6.7

Comfort

8.2

Reviews

1 / 11
10.0
Excellent

Dena,Dec 2024

LAS - BDL

It was comfortable and the crew was great! A few free snacks offered would be nice!

Crew

8.8

Boarding

8.3

Overall

8.1

Entertainment

6.6

Food

6.7

Comfort

8.2

Reviews

1 / 11
10.0
Excellent

Dena,Dec 2024

LAS - BDL

It was comfortable and the crew was great! A few free snacks offered would be nice!

Related info for your journey

Find useful and relevant information for your journey from Durham to South Carolina. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
  • What are the cheapest airlines to fly from Durham to South Carolina one-way?

    For one-way options, check prices for Breeze Airways. According to our data, you can fly for as low as $48. Users have also found prices from $84 and $101 on Spirit Airlines and Frontier, respectively.

  • What are the most popular routes from Durham to South Carolina?

  • Can I find deals for flights from Durham to South Carolina that include hotel bookings?

    Yes. In addition to deals on Durham to South Carolina flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Durham to South Carolina?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Durham to South Carolina.

  • Can I find deals for business class flights from Durham to South Carolina?

    Yes. Cheapflights offers flight deals from Durham to South Carolina by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Durham to South Carolina?

    Currently, August is the cheapest month in which you can book a flight from Durham to South Carolina (average of $217). Flying from Durham to South Carolina in March is currently the most expensive (average of $335). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Browse thousands of different options on Cheapflights for your next trip

Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.

Alternative routes for Durham to South Carolina

See prices for flight routes from nearby airports that may be better suited for you.

Top 4 airlines flying from Durham to South Carolina

Discover the top 4 airlines that operate flights from Durham to South Carolina. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated April 17, 2025.
AirlineCheapestAverageFlexibilityOn-time
Breeze AirwaysCheapest$71Average$110FlexibilityNo cancel feeOn-timeN/A
Spirit AirlinesCheapest$89Average$130FlexibilityNo cancel feeOn-time65%
DeltaCheapest$158Average$486FlexibilityNo cancel feeOn-timeN/A
American AirlinesCheapest$228Average$427FlexibilityNo cancel feeOn-time71%

100% Free

Cheapflights is completely free to use, so you can start saving the moment you arrive.

Book with Flexibility

Our users can plan ahead with confidence and find flights with no change fees

Travel Smart

Millions of people come to us for their flight needs every year. We help make travel planning easy by providing useful insights and data-driven graphs that can inform your decisions.