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$41+ Cheap flights from Detroit Metropolitan Wayne County Airport (DTW) to South Carolina

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 4/21. Fares are subject to change and may not be available on all flights or dates of travel.
DTW — CHS
Apr 1 — Apr 81
Tue 4/1
Tue 4/8
1 adult, Economy
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Cheap flight deals from Detroit to South Carolina

Keep the following information in mind while searching for Detroit to South Carolina flight deals. Data was last updated March 27, 2025.

Most accurate provider

FlightHub
3 stars

Most trusted provider

FlightHub
3 stars

Round-trip from

$127
(Kiwi.com)

One-way from

$41
(FlightHub)

Popular in

December

Cheapest in

October

Average price

$301

Good round-trip deal

$148 or less

Good one-way deal

$64 or less
Provider with most accurate pricing for Detroit (DTT)-Myrtle Beach Intl flight deals.
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Provider most trusted by Cheapflights users for Detroit (DTT)-Myrtle Beach Intl flights.
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From Detroit Metropolitan Wayne County to South Carolina
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One-way flight from Detroit Metropolitan Wayne County to South Carolina
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Highest demand for flights based on searches. 25% potential increase in price ($79 potential increase over avg. RT price).
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Cheapest flight prices on average. 5% potential price decrease ($12 potential savings vs. average RT price).
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Average for round-trip flights in March 2025
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Price to beat on a round-trip flight from Detroit Metropolitan Wayne County to South Carolina.
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Price to beat on a one-way flight from Detroit Metropolitan Wayne County to South Carolina.
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Find flight deals from Detroit to South Carolina

Cheapest flights from Detroit to South Carolina
Explore the most affordable flight options available from Detroit to South Carolina. Find the lowest fares from popular airlines and budget airlines, with prices last updated on March 27, 2025.

This Cheapflightsfares deal was found by Cheapflights users on 3/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 4/264:18 pmDTW - MYR
Nonstop1h 49mSpirit Airlines
Sat 5/311:14 amMYR - DTW
Nonstop1h 59mSpirit Airlines
Deal found 3/26$132
This American Airlines deal was found by Cheapflights users on 3/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 4/203:36 pmDTW - MYR
1 stop3h 24mAmerican Airlines
Tue 4/227:48 pmMYR - DTW
1 stop4h 16mAmerican Airlines
Deal found 3/26$169
This Frontier deal was found by Cheapflights users on 3/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/39:08 pmDTW - CLT
1 stop10h 35mFrontier
Mon 4/79:16 pmCLT - DTW
1 stop10h 44mFrontier
Deal found 3/26$198
This CheapOair deal was found by Cheapflights users on 3/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 4/211:06 pmDTW - CLT
1 stop21h 06mSpirit Airlines
Sun 4/276:00 amCLT - DTW
1 stop26h 20mSpirit Airlines
Deal found 3/25$199
This CheapOair deal was found by Cheapflights users on 3/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 5/198:40 amDTW - CLT
Nonstop1h 52mMultiple Airlines
Sun 5/255:27 pmCLT - DTW
1 stop17h 31mMultiple Airlines
Deal found 3/26$202
This American Airlines deal was found by Cheapflights users on 3/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/67:55 amDTW - HHH
1 stop6h 48mAmerican Airlines
Tue 5/133:13 pmHHH - DTW
1 stop5h 21mAmerican Airlines
Deal found 3/26$217
This Mytrip deal was found by Cheapflights users on 3/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 4/2712:41 pmDTW - GSP
1 stop26h 24mMultiple Airlines
Fri 5/93:55 pmGSP - DTW
1 stop19h 20mMultiple Airlines
Deal found 3/26$219
This CheapOair deal was found by Cheapflights users on 3/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/163:23 pmDTW - CHS
1 stop6h 46mSpirit Airlines
Sun 5/189:43 amCHS - DTW
1 stop23h 32mSpirit Airlines
Deal found 3/25$223
This Mytrip deal was found by Cheapflights users on 3/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 4/116:18 pmDTW - CHS
1 stop23h 27mMultiple Airlines
Sun 4/138:14 pmCHS - DTW
1 stop18h 59mMultiple Airlines
Deal found 3/25$226
This Delta deal was found by Cheapflights users on 3/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/138:45 amDTW - MYR
Nonstop1h 53mDelta
Tue 5/206:00 amMYR - DTW
1 stop6h 55mDelta
Deal found 3/26$229
This American Airlines deal was found by Cheapflights users on 3/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 4/253:12 pmDTW - SAV
1 stop6h 43mAmerican Airlines
Tue 4/295:55 pmSAV - DTW
1 stop5h 22mAmerican Airlines
Deal found 3/26$237
This Southwest deal was found by Cheapflights users on 3/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/176:45 amDTW - SAV
2 stops11h 50mSouthwest
Tue 5/206:00 pmSAV - DTW
1 stop4h 40mSouthwest
Deal found 3/24$242

Cheapflights Fare Finder

Customize your flight search to find flights from Detroit to South Carolina that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated March 27, 2025.
Use the filters below to find and compare flights from Detroit Metropolitan Wayne County Airport to South Carolina that are best for you.

Fly from

Detroit

Fly to

South Carolina

Route

Depart

Return

Price

DetroitMyrtle Beach

DTW - MYR

DTWMYR

Detroit Metropolitan Wayne County

Sat 4/26

4:18 pm-6:07 pm

Nonstop1h 49m

Myrtle Beach Intl

Sat 5/3

11:14 am-1:13 pm

Nonstop1h 59m

$132

DetroitMyrtle Beach

DTW - MYR

DTWMYR

Detroit Metropolitan Wayne County

Sun 4/20

3:36 pm-7:00 pm

1 stop3h 24m

Myrtle Beach Intl

Tue 4/22

7:48 pm-12:04 am

1 stop4h 16m

$169

DetroitCharlotte

DTW - CLT

DTWCLT

Detroit Metropolitan Wayne County

Tue 4/8

8:03 pm-7:13 am

1 stop11h 10m

Charlotte Douglas

Thu 4/10

11:20 am-8:03 pm

1 stop8h 43m

$198

DetroitCharlotte

DTW - CLT

DTWCLT

Detroit Metropolitan Wayne County

Mon 4/21

1:06 pm-10:12 am

1 stop21h 06m

Charlotte Douglas

Sun 4/27

6:00 am-8:20 am

1 stop26h 20m

$199

DetroitCharlotte

DTW - CLT

DTWCLT

Detroit Metropolitan Wayne County

Tue 4/8

5:42 pm-12:32 am

1 stop6h 50m

Charlotte Douglas

Fri 4/11

9:16 pm-8:00 am

1 stop10h 44m

$200

DetroitHilton Head Island

DTW - HHH

DTWHHH

Detroit Metropolitan Wayne County

Tue 5/6

7:55 am-2:43 pm

1 stop6h 48m

Hilton Head Island

Tue 5/13

3:13 pm-8:34 pm

1 stop5h 21m

$217

DetroitGreenville

DTW - GSP

DTWGSP

Detroit Metropolitan Wayne County

Sun 4/27

12:41 pm-3:05 pm

1 stop26h 24m

Greenville

Fri 5/9

3:55 pm-11:15 am

1 stop19h 20m

$219

DetroitCharleston

DTW - CHS

DTWCHS

Detroit Metropolitan Wayne County

Fri 5/16

3:23 pm-10:09 pm

1 stop6h 46m

Charleston

Sun 5/18

9:43 am-9:15 am

1 stop23h 32m

$223

DetroitCharleston

DTW - CHS

DTWCHS

Detroit Metropolitan Wayne County

Fri 4/11

6:18 pm-5:45 pm

1 stop23h 27m

Charleston

Sun 4/13

8:14 pm-3:13 pm

1 stop18h 59m

$226

DetroitMyrtle Beach

DTW - MYR

DTWMYR

Detroit Metropolitan Wayne County

Tue 5/13

8:45 am-10:38 am

Nonstop1h 53m

Myrtle Beach Intl

Tue 5/20

6:00 am-12:55 pm

1 stop6h 55m

$229

Flights are sorted by cheapest round-trip flights first.

Deals found on 3/26

Showing 1-10 of 60 results
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Best time to book a flight from Detroit to South Carolina

Have a flexible travel schedule? Discover the best time to fly to South Carolina from Detroit with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Detroit Metropolitan Wayne County Airport to South Carolina

What is the cheapest month to book a flight from Detroit Metropolitan Wayne County Airport to South Carolina?

Currently, August is the cheapest month in which you can book a flight from Detroit Metropolitan Wayne County Airport to South Carolina (average of $217). Flying from Detroit Metropolitan Wayne County Airport to South Carolina in March is currently the most expensive (average of $335). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from DTW to SC?

Find hourly flight availability from Detroit to South Carolina. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated March 27, 2025.

When flying from Detroit Metropolitan Wayne County Airport to South Carolina, the time of day you decide to fly out makes little to no difference towards the overall price you’ll pay on tickets.

Weekly flight availability from Detroit Metropolitan Wayne County Airport to South Carolina

Explore weekly flight availability from Detroit to South Carolina. Discover flights operating on different days of the week, giving you the flexibility to choose a travel day that best fits your plans. Compare info to find the most convenient option for your journey. Data last updated March 27, 2025.

The most flights from DTW to USSC are scheduled on a Wednesday (2 on average). You will have fewer flight options on Monday, which is when the least amount of flights are scheduled (1 on average).

Rainfall in South Carolina by month

Plan your trip to South Carolina by taking into account the average rainfall totals by month.

In terms of precipitation, rainfall in South Carolina ranges from 3.0 - 6.5 inches per month. July is typically the wettest month, when rainfall can reach 6.5 in. November is typically the driest time to visit South Carolina when rainfall is around 3.0 in.

Temperature in South Carolina by month

Plan your trip to South Carolina by taking into account the average temperature totals by month.

If weather is an important factor for your trip to South Carolina, use this chart to help with planning. For those seeking warmer temperatures, July is the ideal time of year to visit, when temperatures reach an average of 78.8 F. Travelers looking to avoid the cold should look outside of January, when temperatures are typically at their lowest (around 44.6 F).

Reviews of airlines servicing South Carolina

Get insights into the airlines that provide service to South Carolina. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to South Carolina. Reviews last updated March 27, 2025.
See what other customers who have flown with Southwest, Delta and United Airlines from Detroit to South Carolina have to say. You can also see how each airline compares in terms of entertainment options, comfort, food, crew/service, and boarding process.
Southwest
8.1
Very good
4,273 reviews

Food

7.1

Entertainment

7.6

Comfort

8.1

Overall

8.1

Boarding

8.2

Crew

8.6

Reviews

1 / 20
8.0
Excellent

Ila,Mar 2025

HOU - DAL

Our original flight was delayed. We were able to change our flight and got home at close to the same time. Looking forward to when you have assigned seating.
Southwest
8.1
Very good
4,273 reviews
Southwest
8.1
Very good
4,273 reviews

Food

7.1

Entertainment

7.6

Comfort

8.1

Overall

8.1

Boarding

8.2

Crew

8.6

Reviews

1 / 20
8.0
Excellent

Ila,Mar 2025

HOU - DAL

Our original flight was delayed. We were able to change our flight and got home at close to the same time. Looking forward to when you have assigned seating.
Delta
8.0
Very good
7,895 reviews
Southwest
8.1
Very good
4,273 reviews

Food

7.1

Entertainment

7.6

Comfort

8.1

Overall

8.1

Boarding

8.2

Crew

8.6

Reviews

1 / 20
8.0
Excellent

Ila,Mar 2025

HOU - DAL

Our original flight was delayed. We were able to change our flight and got home at close to the same time. Looking forward to when you have assigned seating.
United Airlines
7.4
Good
8,603 reviews
Southwest
8.1
Very good
4,273 reviews

Food

7.1

Entertainment

7.6

Comfort

8.1

Overall

8.1

Boarding

8.2

Crew

8.6

Reviews

1 / 20
8.0
Excellent

Ila,Mar 2025

HOU - DAL

Our original flight was delayed. We were able to change our flight and got home at close to the same time. Looking forward to when you have assigned seating.
American Airlines
7.2
Good
10,000 reviews
Southwest
8.1
Very good
4,273 reviews

Food

7.1

Entertainment

7.6

Comfort

8.1

Overall

8.1

Boarding

8.2

Crew

8.6

Reviews

1 / 20
8.0
Excellent

Ila,Mar 2025

HOU - DAL

Our original flight was delayed. We were able to change our flight and got home at close to the same time. Looking forward to when you have assigned seating.
Spirit Airlines
6.3
Okay
7,880 reviews
Southwest
8.1
Very good
4,273 reviews

Food

7.1

Entertainment

7.6

Comfort

8.1

Overall

8.1

Boarding

8.2

Crew

8.6

Reviews

1 / 20
8.0
Excellent

Ila,Mar 2025

HOU - DAL

Our original flight was delayed. We were able to change our flight and got home at close to the same time. Looking forward to when you have assigned seating.

Related info for your journey

Find useful and relevant information for your journey from Detroit to South Carolina. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly from for flights from Detroit to South Carolina?

    If you book a flight to South Carolina from Detroit, you will be flying from Detroit Metropolitan Wayne County, which is the city’s only airport. Detroit Metropolitan Wayne County (DTW) is located 17.3 mi from the center of Detroit.

  • What are the cheapest airlines to fly from Detroit Metropolitan Wayne County Airport to South Carolina one-way?

    To fly one-way, consider booking your trip with Spirit Airlines, which is currently one of the cheapest options available, starting at $41. American Airlines flights start at $100 while deals on Frontier start at $108 one-way.

  • What are the most popular routes from Detroit Metropolitan Wayne County Airport to South Carolina?

    When deciding which route to take from Detroit Metropolitan Wayne County Airport to South Carolina consider Detroit Metropolitan Wayne County - Charleston, Detroit Metropolitan Wayne County - Charlotte Douglas or Detroit Metropolitan Wayne County - Myrtle Beach Intl as they are the most popular.

  • What are the most reliable airlines from Detroit Metropolitan Wayne County Airport to South Carolina?

    The top 3 most reliable airlines when flying from Detroit Metropolitan Wayne County Airport to South Carolina are SkyWest Airlines (84%), Delta (84%) and WestJet (79%).

  • What are the cheapest flights from Detroit Metropolitan Wayne County Airport to South Carolina?

    Looking for the cheapest flight from Detroit Metropolitan Wayne County Airport to South Carolina? While on average our users pay $434, our data indicates the cheapest price to be $198. The most popular route (Detroit Metropolitan Wayne County - Charleston), is priced around $84.

  • Can I find deals for flights from Detroit to South Carolina that include hotel bookings?

    Yes. In addition to deals on Detroit to South Carolina flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Detroit to South Carolina?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Detroit to South Carolina.

  • Can I find deals for business class flights from Detroit to South Carolina?

    Yes. Cheapflights offers flight deals from Detroit to South Carolina by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Detroit Metropolitan Wayne County Airport to South Carolina?

    Currently, August is the cheapest month in which you can book a flight from Detroit Metropolitan Wayne County Airport to South Carolina (average of $217). Flying from Detroit Metropolitan Wayne County Airport to South Carolina in March is currently the most expensive (average of $335). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

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Top 4 airlines flying from Detroit to South Carolina

Discover the top 4 airlines that operate flights from Detroit to South Carolina. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated March 27, 2025.
AirlineCheapestAverageFlexibilityOn-time
Spirit AirlinesCheapest$70Average$160FlexibilityNo cancel feeOn-time65%
DeltaCheapest$141Average$389FlexibilityNo cancel feeOn-timeN/A
American AirlinesCheapest$174Average$369FlexibilityNo cancel feeOn-time71%
SouthwestCheapest$236Average$381FlexibilityNo cancel feeOn-time63%
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