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$38+ Cheap flights from Detroit Metropolitan Wayne County Airport (DTW) to South Carolina

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 3/19. Fares are subject to change and may not be available on all flights or dates of travel.
DTW — CHS
Feb 25 — Mar 41
Tue 2/25
Tue 3/4
1 adult, Economy
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Cheap flight deals from Detroit to South Carolina

Keep the following information in mind while searching for Detroit to South Carolina flight deals. Data was last updated February 20, 2025.

Most accurate provider

FlightHub
3 stars

Most trusted provider

FlightHub
3 stars

Round-trip from

$151
(Cheapflightsfares)

One-way from

$38
(Kiwi.com)

Popular in

December

Cheapest in

April

Average price

$274

Good round-trip deal

$170 or less

Good one-way deal

$137 or less
Provider with most accurate pricing for Detroit (DTT)-Myrtle Beach Intl flight deals.
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Provider most trusted by Cheapflights users for Detroit (DTT)-Myrtle Beach Intl flights.
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From Detroit Metropolitan Wayne County to South Carolina
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One-way flight from Detroit Metropolitan Wayne County to South Carolina
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Highest demand for flights based on searches. 25% potential increase in price ($78 potential increase over avg. RT price).
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Cheapest flight prices on average. 5% potential price decrease ($12 potential savings vs. average RT price).
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Average for round-trip flights in February 2025
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Price to beat on a round-trip flight from Detroit Metropolitan Wayne County to South Carolina.
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Price to beat on a one-way flight from Detroit Metropolitan Wayne County to South Carolina.
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Find flight deals from Detroit to South Carolina

Cheapest flights from Detroit to South Carolina
Explore the most affordable flight options available from Detroit to South Carolina. Find the lowest fares from popular airlines and budget airlines, with prices last updated on February 20, 2025.

This Spirit deal was found by Cheapflights users on 2/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Spirit is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 5/253:07 pmDTW - MYR
Nonstop1h 52mSpirit Airlines
Sat 5/315:00 amMYR - DTW
1 stop12h 49mSpirit Airlines
Deal found 2/20$151
This FlightHub deal was found by Cheapflights users on 2/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure FlightHub is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 3/71:00 pmDTW - CHS
1 stop25h 04mSpirit Airlines
Thu 3/132:59 pmCHS - DTW
1 stop19h 51mSpirit Airlines
Deal found 2/20$187
This Mytrip deal was found by Cheapflights users on 2/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 2/251:32 pmDTW - CHS
2 stops26h 51mMultiple Airlines
Tue 3/47:15 amCHS - DTW
2 stops15h 34mMultiple Airlines
Deal found 2/19$195
This Mytrip deal was found by Cheapflights users on 2/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 3/137:25 amDTW - CLT
2 stops15h 58mSpirit Airlines
Sun 3/1611:45 amCLT - DTW
2 stops33h 55mSpirit Airlines
Deal found 2/19$196
This Mytrip deal was found by Cheapflights users on 2/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 3/51:22 pmDTW - GSP
1 stop24h 32mMultiple Airlines
Mon 3/104:35 pmGSP - DTW
1 stop19h 56mMultiple Airlines
Deal found 2/20$213
This American Airlines deal was found by Cheapflights users on 2/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/26:50 amDTW - CHS
1 stop4h 25mAmerican Airlines
Wed 4/28:22 pmCHS - DTW
1 stop3h 50mAmerican Airlines
Deal found 2/20$217
This Southwest deal was found by Cheapflights users on 2/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 3/176:05 amDTW - MYR
2 stops10h 45mSouthwest
Thu 3/207:55 pmMYR - DTW
1 stop4h 20mSouthwest
Deal found 2/20$222
This Southwest deal was found by Cheapflights users on 2/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 3/251:35 pmDTW - CHS
2 stops7h 15mSouthwest
Wed 3/267:40 amCHS - DTW
2 stops11h 20mSouthwest
Deal found 2/20$227
This American Airlines deal was found by Cheapflights users on 2/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 3/156:50 amDTW - MYR
2 stops7h 14mAmerican Airlines
Fri 3/218:05 pmMYR - DTW
1 stop4h 07mAmerican Airlines
Deal found 2/19$233
This Booking.com deal was found by Cheapflights users on 2/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Booking.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 2/282:02 pmDTW - CLT
1 stop5h 23mMultiple Airlines
Mon 3/107:38 pmCLT - DTW
1 stop12h 24mMultiple Airlines
Deal found 2/19$236
This American Airlines deal was found by Cheapflights users on 2/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 3/166:00 amDTW - GSP
1 stop4h 04mAmerican Airlines
Mon 3/176:29 pmGSP - DTW
1 stop5h 43mAmerican Airlines
Deal found 2/20$237
This Gotogate deal was found by Cheapflights users on 2/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Gotogate is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 2/237:59 pmDTW - CLT
1 stop11h 09mFrontier
Wed 2/267:44 pmCLT - DTW
1 stop14h 59mFrontier
Deal found 2/19$241

Find flights from Detroit to South Carolina within your budget

Customize your flight search to find flights from Detroit to South Carolina that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated February 20, 2025.

Fly from

Detroit

Fly to

South Carolina

Route

Depart

Return

Price

DetroitMyrtle Beach

DTW - MYR

DTWMYR

Detroit Metropolitan Wayne County

Thu 3/27

11:53 am-1:45 pm

Nonstop1h 52m

Myrtle Beach Intl

Fri 4/4

8:15 am-10:16 am

Nonstop2h 01m

$151

DetroitCharleston

DTW - CHS

DTWCHS

Detroit Metropolitan Wayne County

Fri 3/7

1:00 pm-2:04 pm

1 stop25h 04m

Charleston

Thu 3/13

2:59 pm-10:50 am

1 stop19h 51m

$187

DetroitCharleston

DTW - CHS

DTWCHS

Detroit Metropolitan Wayne County

Tue 2/25

1:32 pm-4:23 pm

2 stops26h 51m

Charleston

Tue 3/4

7:15 am-10:49 pm

2 stops15h 34m

$195

DetroitCharlotte

DTW - CLT

DTWCLT

Detroit Metropolitan Wayne County

Thu 3/13

7:25 am-11:23 pm

2 stops15h 58m

Charlotte Douglas

Sun 3/16

11:45 am-9:40 pm

2 stops33h 55m

$196

DetroitGreenville

DTW - GSP

DTWGSP

Detroit Metropolitan Wayne County

Wed 3/5

1:22 pm-1:54 pm

1 stop24h 32m

Greenville

Mon 3/10

4:35 pm-12:31 pm

1 stop19h 56m

$213

DetroitCharleston

DTW - CHS

DTWCHS

Detroit Metropolitan Wayne County

Wed 4/2

6:50 am-11:15 am

1 stop4h 25m

Charleston

Wed 4/2

8:22 pm-12:12 am

1 stop3h 50m

$217

DetroitCharlotte

DTW - CLT

DTWCLT

Detroit Metropolitan Wayne County

Fri 3/28

10:45 am-5:44 pm

1 stop6h 59m

Charlotte Douglas

Sun 3/30

6:00 am-8:27 am

1 stop26h 27m

$218

DetroitMyrtle Beach

DTW - MYR

DTWMYR

Detroit Metropolitan Wayne County

Mon 3/17

6:05 am-4:50 pm

2 stops10h 45m

Myrtle Beach Intl

Thu 3/20

7:55 pm-12:15 am

1 stop4h 20m

$222

DetroitCharleston

DTW - CHS

DTWCHS

Detroit Metropolitan Wayne County

Tue 3/25

1:35 pm-8:50 pm

2 stops7h 15m

Charleston

Wed 3/26

7:40 am-7:00 pm

2 stops11h 20m

$227

DetroitMyrtle Beach

DTW - MYR

DTWMYR

Detroit Metropolitan Wayne County

Sat 3/15

6:50 am-2:04 pm

2 stops7h 14m

Myrtle Beach Intl

Fri 3/21

8:05 pm-12:12 am

1 stop4h 07m

$233

Flights are sorted by cheapest round-trip flights first.

Deals found on 2/19

Showing 1-10 of 60 results
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Best time to book a flight from Detroit to South Carolina

Have a flexible travel schedule? Discover the best time to fly to South Carolina from Detroit with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Travel insights for flights from Detroit to South Carolina

Get recent, data-driven insights about flights from Detroit to South Carolina including ideal travel times, pricing trends, and more.

What is the cheapest month to book a flight from Detroit Metropolitan Wayne County Airport to South Carolina?

Currently, August is the cheapest month in which you can book a flight from Detroit Metropolitan Wayne County Airport to South Carolina (average of $217). Flying from Detroit Metropolitan Wayne County Airport to South Carolina in March is currently the most expensive (average of $335). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from DTW to SC?

Find hourly flight availability from Detroit to South Carolina. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated February 20, 2025.

When flying from Detroit Metropolitan Wayne County Airport to South Carolina, the time of day you decide to fly out makes little to no difference towards the overall price you’ll pay on tickets.

Weekly flight availability from Detroit Metropolitan Wayne County Airport to South Carolina

Explore weekly flight availability from Detroit to South Carolina. Discover flights operating on different days of the week, giving you the flexibility to choose a travel day that best fits your plans. Compare info to find the most convenient option for your journey. Data last updated February 20, 2025.

The most flights from DTW to USSC are scheduled on a Monday (3 on average). You will have fewer flight options on Sunday, which is when the least amount of flights are scheduled (2 on average).

Rainfall in South Carolina by month

Plan your trip to South Carolina by taking into account the average rainfall totals by month.

In terms of precipitation, rainfall in South Carolina ranges from 3.0 - 6.5 inches per month. July is typically the wettest month, when rainfall can reach 6.5 in. November is typically the driest time to visit South Carolina when rainfall is around 3.0 in.

Temperature in South Carolina by month

Plan your trip to South Carolina by taking into account the average temperature totals by month.

If weather is an important factor for your trip to South Carolina, use this chart to help with planning. For those seeking warmer temperatures, July is the ideal time of year to visit, when temperatures reach an average of 78.8 F. Travelers looking to avoid the cold should look outside of January, when temperatures are typically at their lowest (around 44.6 F).

Reviews of airlines servicing South Carolina

Get insights into the airlines that provide service to South Carolina. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to South Carolina. Reviews last updated February 20, 2025.
See what other customers who have flown with Southwest, Delta and JetBlue from Detroit to South Carolina have to say. You can also see how each airline compares in terms of entertainment options, comfort, food, crew/service, and boarding process.
Southwest
8.1
Very good
4,411 reviews

Crew

8.7

Food

7.1

Comfort

8.1

Overall

8.1

Boarding

8.2

Entertainment

7.6

Reviews

1 / 20

2.0
Mediocre

Anonymous,Feb 2025

MCO - STL

Cancelled at last minute, SWA unable to assist in formulating alternate plans. Wound up renting a car and driving 13 hours to beat bad weather forecast at home. Not SWA’s fault that there was significant bad weather across the country.

Southwest
8.1
Very good
4,411 reviews
Southwest
8.1
Very good
4,411 reviews

Crew

8.7

Food

7.1

Comfort

8.1

Overall

8.1

Boarding

8.2

Entertainment

7.6

Reviews

1 / 20

2.0
Mediocre

Anonymous,Feb 2025

MCO - STL

Cancelled at last minute, SWA unable to assist in formulating alternate plans. Wound up renting a car and driving 13 hours to beat bad weather forecast at home. Not SWA’s fault that there was significant bad weather across the country.

Delta
8.0
Very good
8,220 reviews
Southwest
8.1
Very good
4,411 reviews

Crew

8.7

Food

7.1

Comfort

8.1

Overall

8.1

Boarding

8.2

Entertainment

7.6

Reviews

1 / 20

2.0
Mediocre

Anonymous,Feb 2025

MCO - STL

Cancelled at last minute, SWA unable to assist in formulating alternate plans. Wound up renting a car and driving 13 hours to beat bad weather forecast at home. Not SWA’s fault that there was significant bad weather across the country.

JetBlue
7.4
Good
3,070 reviews
Southwest
8.1
Very good
4,411 reviews

Crew

8.7

Food

7.1

Comfort

8.1

Overall

8.1

Boarding

8.2

Entertainment

7.6

Reviews

1 / 20

2.0
Mediocre

Anonymous,Feb 2025

MCO - STL

Cancelled at last minute, SWA unable to assist in formulating alternate plans. Wound up renting a car and driving 13 hours to beat bad weather forecast at home. Not SWA’s fault that there was significant bad weather across the country.

United Airlines
7.4
Good
8,766 reviews
Southwest
8.1
Very good
4,411 reviews

Crew

8.7

Food

7.1

Comfort

8.1

Overall

8.1

Boarding

8.2

Entertainment

7.6

Reviews

1 / 20

2.0
Mediocre

Anonymous,Feb 2025

MCO - STL

Cancelled at last minute, SWA unable to assist in formulating alternate plans. Wound up renting a car and driving 13 hours to beat bad weather forecast at home. Not SWA’s fault that there was significant bad weather across the country.

American Airlines
7.2
Good
10,000 reviews
Southwest
8.1
Very good
4,411 reviews

Crew

8.7

Food

7.1

Comfort

8.1

Overall

8.1

Boarding

8.2

Entertainment

7.6

Reviews

1 / 20

2.0
Mediocre

Anonymous,Feb 2025

MCO - STL

Cancelled at last minute, SWA unable to assist in formulating alternate plans. Wound up renting a car and driving 13 hours to beat bad weather forecast at home. Not SWA’s fault that there was significant bad weather across the country.

Related info for your journey

Find useful and relevant information for your journey from Detroit to South Carolina. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly from for flights from Detroit to South Carolina?

    If you book a flight to South Carolina from Detroit, you will be flying from Detroit Metropolitan Wayne County, which is the city’s only airport. Detroit Metropolitan Wayne County (DTW) is located 17.3 mi from the center of Detroit.

  • What are the cheapest airlines to fly from Detroit Metropolitan Wayne County Airport to South Carolina one-way?

    To fly one-way, consider booking your trip with Spirit Airlines, which is currently one of the cheapest options available, starting at $38. Frontier flights start at $64 while deals on American Airlines start at $84 one-way.

  • What are the most popular routes from Detroit Metropolitan Wayne County Airport to South Carolina?

    When deciding which route to take from Detroit Metropolitan Wayne County Airport to South Carolina consider Detroit Metropolitan Wayne County - Charleston, Detroit Metropolitan Wayne County - Myrtle Beach Intl or Detroit Metropolitan Wayne County - Charlotte Douglas as they are the most popular.

  • What are the most reliable airlines from Detroit Metropolitan Wayne County Airport to South Carolina?

    The top 3 most reliable airlines when flying from Detroit Metropolitan Wayne County Airport to South Carolina are Korean Air (66%), SkyWest Airlines (65%) and Delta (61%).

  • What are the cheapest flights from Detroit Metropolitan Wayne County Airport to South Carolina?

    Looking for the cheapest flight from Detroit Metropolitan Wayne County Airport to South Carolina? While on average our users pay $391, our data indicates the cheapest price to be $168. The most popular route (Detroit Metropolitan Wayne County - Charleston), is priced around $83.

  • Can I find deals for flights from Detroit to South Carolina that include hotel bookings?

    Yes. In addition to deals on Detroit to South Carolina flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Detroit to South Carolina?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Detroit to South Carolina.

  • Can I find deals for business class flights from Detroit to South Carolina?

    Yes. Cheapflights offers flight deals from Detroit to South Carolina by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Detroit Metropolitan Wayne County Airport to South Carolina?

    Currently, August is the cheapest month in which you can book a flight from Detroit Metropolitan Wayne County Airport to South Carolina (average of $217). Flying from Detroit Metropolitan Wayne County Airport to South Carolina in March is currently the most expensive (average of $335). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

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Alternative routes for Detroit to South Carolina

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Top 4 airlines flying from Detroit to South Carolina

Discover the top 4 airlines that operate flights from Detroit to South Carolina. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated February 20, 2025.
AirlineCheapestAverageFlexibilityOn-time
Spirit AirlinesCheapest$69Average$163FlexibilityNo cancel feeOn-time65%
DeltaCheapest$139Average$415FlexibilityNo cancel feeOn-timeN/A
American AirlinesCheapest$174Average$380FlexibilityNo cancel feeOn-time71%
SouthwestCheapest$178Average$415FlexibilityNo cancel feeOn-time63%
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