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$38+ Cheap flights from Detroit (DTT) to South Carolina

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 3/19. Fares are subject to change and may not be available on all flights or dates of travel.
DTT — CHS
Şub 27 — Mar 61
Per 2/27
Per 3/6
1 adult, Economy
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Cheap flight deals from Detroit to South Carolina

Keep the following information in mind while searching for Detroit to South Carolina flight deals. Data was last updated Şubat 22, 2025.

Most accurate provider

FlightHub
3 stars

Most trusted provider

FlightHub
3 stars

Round-trip from

$150
(Cheapflightsfares)

One-way from

$38
(Kiwi.com)

Popular in

December

Cheapest in

April

Average price

$274

Good round-trip deal

$170 or less

Good one-way deal

$137 or less
Provider with most accurate pricing for Detroit (DTT)-Myrtle Beach Intl flight deals.
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Provider most trusted by Cheapflights users for Detroit (DTT)-Myrtle Beach Intl flights.
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From Detroit (DTT) to South Carolina
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One-way flight from Detroit (DTT) to South Carolina
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Highest demand for flights based on searches. 25% potential increase in price ($78 potential increase over avg. RT price).
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Cheapest flight prices on average. 5% potential price decrease ($12 potential savings vs. average RT price).
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Average for round-trip flights in February 2025
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Price to beat on a round-trip flight from Detroit (DTT) to South Carolina.
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Price to beat on a one-way flight from Detroit (DTT) to South Carolina.
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Find flight deals from Detroit to South Carolina

Cheapest flights from Detroit to South Carolina
Explore the most affordable flight options available from Detroit to South Carolina. Find the lowest fares from popular airlines and budget airlines, with prices last updated on Şubat 22, 2025.

This Cheapflightsfares deal was found by Cheapflights users on 2/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Çar 4/25:00 amDTW - MYR
1 stop12h 36mSpirit Airlines
Cmt 4/56:15 amMYR - DTW
1 stop6h 16mSpirit Airlines
Deal found 2/21$150
This Mytrip deal was found by Cheapflights users on 2/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Per 3/137:52 pmDTW - GSP
1 stop20h 01mMultiple Airlines
Pzt 3/179:08 pmGSP - DTW
1 stop24h 32mMultiple Airlines
Deal found 2/21$179
This Mytrip deal was found by Cheapflights users on 2/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Pzt 3/108:50 pmDTW - CHS
2 stops17h 14mSpirit Airlines
Cum 3/1410:48 amCHS - DTW
2 stops21h 39mSpirit Airlines
Deal found 2/21$187
This Mytrip deal was found by Cheapflights users on 2/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Paz 3/25:41 pmDTW - CHS
1 stop14h 46mMultiple Airlines
Cum 3/72:59 pmCHS - DTW
1 stop17h 28mMultiple Airlines
Deal found 2/21$190
This CheapOair deal was found by Cheapflights users on 2/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Cum 4/118:20 pmDTW - CLT
1 stop11h 38mMultiple Airlines
Paz 4/136:24 pmCLT - DTW
1 stop5h 55mMultiple Airlines
Deal found 2/21$195
This Mytrip deal was found by Cheapflights users on 2/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Cum 3/78:50 pmDTW - CLT
2 stops26h 33mSpirit Airlines
Paz 3/911:45 amCLT - DTW
2 stops35h 10mSpirit Airlines
Deal found 2/21$196
This Delta deal was found by Cheapflights users on 2/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sal 4/110:15 amDTW - CHS
Nonstop2h 05mDelta
Sal 4/151:00 pmCHS - DTW
Nonstop2h 10mDelta
Deal found 2/21$199
This American Airlines deal was found by Cheapflights users on 2/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Pzt 3/1010:17 amDTW - CHS
1 stop4h 00mAmerican Airlines
Pzt 3/106:08 pmCHS - DTW
1 stop6h 04mAmerican Airlines
Deal found 2/20$211
This Southwest deal was found by Cheapflights users on 2/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Pzt 3/176:05 amDTW - MYR
2 stops10h 45mSouthwest
Per 3/207:00 amMYR - DTW
1 stop5h 20mSouthwest
Deal found 2/21$222
This Southwest deal was found by Cheapflights users on 2/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Pzt 3/176:05 amDTW - CHS
2 stops11h 05mSouthwest
Pzt 3/248:05 pmCHS - DTW
1 stop4h 10mSouthwest
Deal found 2/21$222
This American Airlines deal was found by Cheapflights users on 2/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sal 3/2511:14 amDTW - MYR
1 stop6h 45mAmerican Airlines
Sal 4/86:05 pmMYR - DTW
2 stops6h 30mAmerican Airlines
Deal found 2/21$233
This American Airlines deal was found by Cheapflights users on 2/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Çar 5/76:00 amDTW - HHH
1 stop4h 30mAmerican Airlines
Sal 5/1311:00 amHHH - DTW
1 stop3h 45mAmerican Airlines
Deal found 2/20$239

Find flights from Detroit to South Carolina within your budget

Customize your flight search to find flights from Detroit to South Carolina that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated Şubat 22, 2025.

Fly from

Detroit

Fly to

South Carolina

Route

Depart

Return

Price

DetroitMyrtle Beach

DTW - MYR

DTWMYR

Detroit Metropolitan Wayne County

Çar 4/2

5:00 am-5:36 pm

1 stop12h 36m

Myrtle Beach Intl

Cmt 4/5

6:15 am-12:31 pm

1 stop6h 16m

$150

DetroitGreenville

DTW - GSP

DTWGSP

Detroit Metropolitan Wayne County

Per 3/13

7:52 pm-3:53 pm

1 stop20h 01m

Greenville

Pzt 3/17

9:08 pm-9:40 pm

1 stop24h 32m

$179

DetroitCharleston

DTW - CHS

DTWCHS

Detroit Metropolitan Wayne County

Pzt 3/10

8:50 pm-2:04 pm

2 stops17h 14m

Charleston

Cum 3/14

10:48 am-8:27 am

2 stops21h 39m

$187

DetroitCharlotte

DTW - CLT

DTWCLT

Detroit Metropolitan Wayne County

Cum 4/11

8:20 pm-7:58 am

1 stop11h 38m

Charlotte Douglas

Paz 4/13

6:24 pm-12:19 am

1 stop5h 55m

$195

DetroitCharlotte

DTW - CLT

DTWCLT

Detroit Metropolitan Wayne County

Cum 3/7

8:50 pm-11:23 pm

2 stops26h 33m

Charlotte Douglas

Paz 3/9

11:45 am-10:55 pm

2 stops35h 10m

$196

DetroitCharleston

DTW - CHS

DTWCHS

Detroit Metropolitan Wayne County

Sal 4/1

10:15 am-12:20 pm

Nonstop2h 05m

Charleston

Sal 4/15

1:00 pm-3:10 pm

Nonstop2h 10m

$199

DetroitCharleston

DTW - CHS

DTWCHS

Detroit Metropolitan Wayne County

Sal 3/4

9:40 pm-9:53 am

1 stop12h 13m

Charleston

Paz 3/9

5:47 pm-10:55 pm

2 stops29h 08m

$200

DetroitCharlotte

DTW - CLT

DTWCLT

Detroit Metropolitan Wayne County

Sal 3/4

7:45 pm-7:08 am

1 stop11h 23m

Charlotte Douglas

Cum 3/7

7:38 pm-8:02 am

1 stop12h 24m

$210

DetroitCharleston

DTW - CHS

DTWCHS

Detroit Metropolitan Wayne County

Pzt 3/10

10:17 am-2:17 pm

1 stop4h 00m

Charleston

Pzt 3/10

6:08 pm-12:12 am

1 stop6h 04m

$211

DetroitMyrtle Beach

DTW - MYR

DTWMYR

Detroit Metropolitan Wayne County

Pzt 3/17

6:05 am-4:50 pm

2 stops10h 45m

Myrtle Beach Intl

Per 3/20

7:00 am-12:20 pm

1 stop5h 20m

$222

Flights are sorted by cheapest round-trip flights first.

Deals found on 2/21

Showing 1-10 of 60 results
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2
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Best time to book a flight from Detroit to South Carolina

Have a flexible travel schedule? Discover the best time to fly to South Carolina from Detroit with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Travel insights for flights from Detroit to South Carolina

Get recent, data-driven insights about flights from Detroit to South Carolina including ideal travel times, pricing trends, and more.

What is the cheapest month to book a flight from Detroit to South Carolina?

Currently, August is the cheapest month in which you can book a flight from Detroit to South Carolina (average of $217). Flying from Detroit to South Carolina in March is currently the most expensive (average of $335). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from DTT to SC?

Find hourly flight availability from Detroit to South Carolina. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated Şubat 22, 2025.

Regardless of the time of day you decide to fly, the ticket price will remain around the same. Book flights from Detroit to South Carolina as you normally would.

Weekly flight availability from Detroit to South Carolina

Explore weekly flight availability from Detroit to South Carolina. Discover flights operating on different days of the week, giving you the flexibility to choose a travel day that best fits your plans. Compare info to find the most convenient option for your journey. Data last updated Şubat 22, 2025.

The most flights from DTT to USSC are scheduled on a Monday (3 on average). You will have fewer flight options on Sunday, which is when the least amount of flights are scheduled (2 on average).

Rainfall in South Carolina by month

Plan your trip to South Carolina by taking into account the average rainfall totals by month.

In terms of precipitation, rainfall in South Carolina ranges from 3.0 - 6.5 inches per month. July is typically the wettest month, when rainfall can reach 6.5 in. November is typically the driest time to visit South Carolina when rainfall is around 3.0 in.

Temperature in South Carolina by month

Plan your trip to South Carolina by taking into account the average temperature totals by month.

If weather is an important factor for your trip to South Carolina, use this chart to help with planning. For those seeking warmer temperatures, July is the ideal time of year to visit, when temperatures reach an average of 78.8 F. Travelers looking to avoid the cold should look outside of January, when temperatures are typically at their lowest (around 44.6 F).

Reviews of airlines servicing South Carolina

Get insights into the airlines that provide service to South Carolina. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to South Carolina. Reviews last updated Şubat 22, 2025.
To help decide which airline to fly from Detroit to South Carolina, see what other customers have to say about Southwest, Delta and JetBlue. You can also see how each airline compares in terms of entertainment options, comfort, food, crew/service, and boarding process.
Southwest
8.1
Very good
4,395 reviews

Overall

8.1

Entertainment

7.6

Crew

8.7

Comfort

8.1

Food

7.1

Boarding

8.2

Reviews

1 / 20

2.0
Mediocre

Anonymous,Feb 2025

MCO - STL

Cancelled at last minute, SWA unable to assist in formulating alternate plans. Wound up renting a car and driving 13 hours to beat bad weather forecast at home. Not SWA’s fault that there was significant bad weather across the country.

Southwest
8.1
Very good
4,395 reviews
Southwest
8.1
Very good
4,395 reviews

Overall

8.1

Entertainment

7.6

Crew

8.7

Comfort

8.1

Food

7.1

Boarding

8.2

Reviews

1 / 20

2.0
Mediocre

Anonymous,Feb 2025

MCO - STL

Cancelled at last minute, SWA unable to assist in formulating alternate plans. Wound up renting a car and driving 13 hours to beat bad weather forecast at home. Not SWA’s fault that there was significant bad weather across the country.

Delta
8.0
Very good
8,203 reviews
Southwest
8.1
Very good
4,395 reviews

Overall

8.1

Entertainment

7.6

Crew

8.7

Comfort

8.1

Food

7.1

Boarding

8.2

Reviews

1 / 20

2.0
Mediocre

Anonymous,Feb 2025

MCO - STL

Cancelled at last minute, SWA unable to assist in formulating alternate plans. Wound up renting a car and driving 13 hours to beat bad weather forecast at home. Not SWA’s fault that there was significant bad weather across the country.

JetBlue
7.4
Good
3,068 reviews
Southwest
8.1
Very good
4,395 reviews

Overall

8.1

Entertainment

7.6

Crew

8.7

Comfort

8.1

Food

7.1

Boarding

8.2

Reviews

1 / 20

2.0
Mediocre

Anonymous,Feb 2025

MCO - STL

Cancelled at last minute, SWA unable to assist in formulating alternate plans. Wound up renting a car and driving 13 hours to beat bad weather forecast at home. Not SWA’s fault that there was significant bad weather across the country.

United Airlines
7.4
Good
8,754 reviews
Southwest
8.1
Very good
4,395 reviews

Overall

8.1

Entertainment

7.6

Crew

8.7

Comfort

8.1

Food

7.1

Boarding

8.2

Reviews

1 / 20

2.0
Mediocre

Anonymous,Feb 2025

MCO - STL

Cancelled at last minute, SWA unable to assist in formulating alternate plans. Wound up renting a car and driving 13 hours to beat bad weather forecast at home. Not SWA’s fault that there was significant bad weather across the country.

American Airlines
7.2
Good
10,000 reviews
Southwest
8.1
Very good
4,395 reviews

Overall

8.1

Entertainment

7.6

Crew

8.7

Comfort

8.1

Food

7.1

Boarding

8.2

Reviews

1 / 20

2.0
Mediocre

Anonymous,Feb 2025

MCO - STL

Cancelled at last minute, SWA unable to assist in formulating alternate plans. Wound up renting a car and driving 13 hours to beat bad weather forecast at home. Not SWA’s fault that there was significant bad weather across the country.

Related info for your journey

Find useful and relevant information for your journey from Detroit to South Carolina. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly from for flights from Detroit to South Carolina?

    Most people fly from Detroit All airports (DTT) if they book a flight from Detroit to South Carolina. Detroit All airports is conveniently located just 0.6 mi from Detroit’s city center.

  • What are the cheapest airlines to fly from Detroit to South Carolina one-way?

    $38 is the cheapest one-way deal found within the past few days, from Spirit Airlines. You may also be able to find cheap deals on Frontier and Southwest, with prices starting from $64 and $100, respectively.

  • What are the most popular routes from Detroit to South Carolina?

    The most popular route from Detroit to South Carolina is Detroit Metropolitan Wayne County - Myrtle Beach Intl. You may also consider Detroit Metropolitan Wayne County - Charleston or Detroit Metropolitan Wayne County - Charlotte Douglas.

  • What are the most reliable airlines from Detroit to South Carolina?

    The top 3 most reliable airlines when flying from Detroit to South Carolina are Korean Air (66%), SkyWest Airlines (65%) and Delta (61%).

  • What are the cheapest flights from Detroit to South Carolina?

    Looking for the cheapest flight from Detroit to South Carolina? While on average our users pay $391, our data indicates the cheapest price to be $168. The most popular route (Detroit Metropolitan Wayne County - Myrtle Beach Intl), is priced around $111.

  • Can I find deals for flights from Detroit to South Carolina that include hotel bookings?

    Yes. In addition to deals on Detroit to South Carolina flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Detroit to South Carolina?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Detroit to South Carolina.

  • Can I find deals for business class flights from Detroit to South Carolina?

    Yes. Cheapflights offers flight deals from Detroit to South Carolina by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Detroit to South Carolina?

    Currently, August is the cheapest month in which you can book a flight from Detroit to South Carolina (average of $217). Flying from Detroit to South Carolina in March is currently the most expensive (average of $335). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

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Alternative routes for Detroit to South Carolina

See prices for flight routes from nearby airports that may be better suited for you.
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Top 4 airlines flying from Detroit to South Carolina

Discover the top 4 airlines that operate flights from Detroit to South Carolina. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated Şubat 22, 2025.
AirlineCheapestAverageFlexibilityOn-time
Spirit AirlinesCheapest$69Average$163FlexibilityNo cancel feeOn-time65%
DeltaCheapest$139Average$415FlexibilityNo cancel feeOn-timeN/A
American AirlinesCheapest$174Average$380FlexibilityNo cancel feeOn-time71%
SouthwestCheapest$178Average$415FlexibilityNo cancel feeOn-time63%
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