HomeSearch by dateVacation packagesHotelsFlight dealsCar rentalTravel tips & news
South Carolina

$55+ Cheap flights from Detroit (DTT) to South Carolina

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 3/10. Fares are subject to change and may not be available on all flights or dates of travel.
DTT — CHS
Jan 26 — Feb 21
Sun 1/26
Sun 2/2
1 adult, Economy
We work with more than 300 partners to bring you better travel deals

Find cheap flights from Detroit to South Carolina with Cheapflights

1. Tell us where you want to go
Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”
2. Select your favorite providers
We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.
3. Compare prices and book
Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.

Cheap flight deals from Detroit to South Carolina

Discover tips and strategies to find the most affordable flight options for your journey from Detroit (DTT) to South Carolina (USSC). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated January 21, 2025.

Round-trip from

$159
(Delta)

One-way from

$55
(Cheapflightsfares)

Good round-trip deal

$177 or less

Good one-way deal

$158 or less
From Detroit (DTT) to South Carolina
Search Deals
One-way flight from Detroit (DTT) to South Carolina
Search Deals
Price to beat on a round-trip flight from Detroit (DTT) to South Carolina.
Search Deals
Price to beat on a one-way flight from Detroit (DTT) to South Carolina.
Search Deals

Find flight deals from Detroit to South Carolina

Cheapest flights from Detroit to South Carolina
Explore the most affordable flight options available from Detroit to South Carolina. Find the lowest fares from popular airlines and budget airlines, with prices last updated on January 21, 2025.

This Delta deal was found by Cheapflights users on 1/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 2/1110:10 amDTW - MYR
Nonstop2h 01mDelta
Sat 2/1512:56 pmMYR - DTW
Nonstop2h 02mDelta
Deal found 1/21$159
This CheapOair deal was found by Cheapflights users on 1/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 2/271:32 pmDTW - MYR
1 stop18h 31mSpirit Airlines
Wed 3/55:30 amMYR - DTW
1 stop10h 47mSpirit Airlines
Deal found 1/21$160
This American Airlines deal was found by Cheapflights users on 1/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 2/73:38 pmDTW - MYR
1 stop6h 50mAmerican Airlines
Mon 2/107:47 pmMYR - DTW
1 stop3h 59mAmerican Airlines
Deal found 1/21$179
This FlightHub deal was found by Cheapflights users on 1/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure FlightHub is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 3/268:00 amDTW - CHS
1 stop5h 19mSpirit Airlines
Mon 3/3110:28 amCHS - DTW
1 stop24h 58mSpirit Airlines
Deal found 1/19$183
This United Airlines deal was found by Cheapflights users on 1/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 2/102:30 pmDTW - CHS
2 stops9h 16mUnited Airlines
Sat 2/154:45 pmCHS - DTW
1 stop6h 45mUnited Airlines
Deal found 1/19$184
This American Airlines deal was found by Cheapflights users on 1/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 4/73:36 pmDTW - CHS
1 stop6h 19mAmerican Airlines
Thu 4/106:08 pmCHS - DTW
1 stop5h 57mAmerican Airlines
Deal found 1/21$197
This Cheapflightsfares deal was found by Cheapflights users on 1/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 3/206:16 amDTW - CLT
1 stop4h 34mSpirit Airlines
Mon 3/247:00 amCLT - DTW
1 stop9h 47mSpirit Airlines
Deal found 1/21$206
This CheapOair deal was found by Cheapflights users on 1/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 2/209:26 pmDTW - CLT
1 stop9h 42mMultiple Airlines
Sun 2/237:16 pmCLT - DTW
1 stop28h 42mMultiple Airlines
Deal found 1/21$208
This American Airlines deal was found by Cheapflights users on 1/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 2/2610:09 amDTW - CLT
Nonstop1h 58mAmerican Airlines
Sat 3/11:00 pmCLT - DTW
Nonstop1h 44mAmerican Airlines
Deal found 1/20$210
This Mytrip deal was found by Cheapflights users on 1/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 5/511:33 amDTW - CHS
2 stops24h 30mMultiple Airlines
Fri 5/99:30 pmCHS - DTW
1 stop13h 11mMultiple Airlines
Deal found 1/20$210
This FlightHub deal was found by Cheapflights users on 1/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure FlightHub is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 2/99:14 pmDTW - CLT
1 stop21h 01mFrontier
Tue 2/188:08 amCLT - DTW
1 stop23h 54mFrontier
Deal found 1/21$216
This Southwest deal was found by Cheapflights users on 1/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/24:30 pmDTW - CHS
1 stop4h 20mSouthwest
Sat 4/56:30 amCHS - DTW
1 stop8h 55mSouthwest
Deal found 1/21$217

Find flights from Detroit to South Carolina within your budget

Customize your flight search to find flights from Detroit to South Carolina that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated January 21, 2025.

Fly from

Any airport

Fly to

Any airport

Route

Depart

Return

Price

DetroitMyrtle Beach

DTW - MYR

DTWMYR

Detroit Metropolitan Wayne County

Tue 2/11

10:10 am-12:11 pm

Nonstop2h 01m

Myrtle Beach Intl

Sat 2/15

12:56 pm-2:58 pm

Nonstop2h 02m

$159

DetroitMyrtle Beach

DTW - MYR

DTWMYR

Detroit Metropolitan Wayne County

Thu 2/27

1:32 pm-8:03 am

1 stop18h 31m

Myrtle Beach Intl

Wed 3/5

5:30 am-4:17 pm

1 stop10h 47m

$160

DetroitMyrtle Beach

DTW - MYR

DTWMYR

Detroit Metropolitan Wayne County

Fri 2/7

3:38 pm-10:28 pm

1 stop6h 50m

Myrtle Beach Intl

Mon 2/10

7:47 pm-11:46 pm

1 stop3h 59m

$179

DetroitCharleston

DTW - CHS

DTWCHS

Detroit Metropolitan Wayne County

Wed 3/26

8:00 am-1:19 pm

1 stop5h 19m

Charleston

Mon 3/31

2:15 pm-12:46 pm

1 stop22h 31m

$186

DetroitCharleston

DTW - CHS

DTWCHS

Detroit Metropolitan Wayne County

Wed 3/19

8:00 am-1:19 pm

1 stop5h 19m

Charleston

Mon 3/24

12:56 pm-11:26 am

3 stops22h 30m

$195

DetroitCharleston

DTW - CHS

DTWCHS

Detroit Metropolitan Wayne County

Mon 4/7

3:36 pm-7:28 pm

1 stop3h 52m

Charleston

Thu 4/17

6:08 pm-12:05 am

1 stop5h 57m

$197

DetroitCharlotte

DTW - CLT

DTWCLT

Detroit Metropolitan Wayne County

Thu 3/20

6:16 am-10:50 am

1 stop4h 34m

Charlotte Douglas

Mon 3/24

7:00 am-4:47 pm

1 stop9h 47m

$206

DetroitCharlotte

DTW - CLT

DTWCLT

Detroit Metropolitan Wayne County

Thu 2/20

9:26 pm-7:08 am

1 stop9h 42m

Charlotte Douglas

Sun 2/23

7:16 pm-11:58 pm

1 stop28h 42m

$208

DetroitCharlotte

DTW - CLT

DTWCLT

Detroit Metropolitan Wayne County

Wed 2/26

10:09 am-12:07 pm

Nonstop1h 58m

Charlotte Douglas

Sat 3/1

1:00 pm-2:44 pm

Nonstop1h 44m

$210

DetroitCharlotte

DTW - CLT

DTWCLT

Detroit Metropolitan Wayne County

Mon 3/24

7:39 pm-11:59 pm

1 stop4h 20m

Charlotte Douglas

Thu 3/27

10:46 am-4:51 pm

1 stop6h 05m

$217

Flights are sorted by cheapest round-trip flights first.

Deals found on 1/21

Showing 1-10 of 60 results
1
2
3
...
6

Best time to book a flight from Detroit to South Carolina

Have a flexible travel schedule? Discover the best time to fly to South Carolina from Detroit with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Travel insights for flights from Detroit to South Carolina

Get recent, data-driven insights about flights from Detroit to South Carolina including ideal travel times, pricing trends, and more.

What is the cheapest month to book a flight from Detroit to South Carolina?

Currently, August is the cheapest month in which you can book a flight from Detroit to South Carolina (average of $217). Flying from Detroit to South Carolina in March is currently the most expensive (average of $335). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from DTT to SC?

Find hourly flight availability from Detroit to South Carolina. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated January 21, 2025.

Regardless of the time of day you decide to fly, the ticket price will remain around the same. Book flights from Detroit to South Carolina as you normally would.

Rainfall in South Carolina by month

Plan your trip to South Carolina by taking into account the average rainfall totals by month.

In terms of precipitation, rainfall in South Carolina ranges from 3.0 - 6.5 inches per month. July is typically the wettest month, when rainfall can reach 6.5 in. November is typically the driest time to visit South Carolina when rainfall is around 3.0 in.

Temperature in South Carolina by month

Plan your trip to South Carolina by taking into account the average temperature totals by month.

If weather is an important factor for your trip to South Carolina, use this chart to help with planning. For those seeking warmer temperatures, July is the ideal time of year to visit, when temperatures reach an average of 78.8 F. Travelers looking to avoid the cold should look outside of January, when temperatures are typically at their lowest (around 44.6 F).

Reviews of airlines servicing South Carolina

Get insights into the airlines that provide service to South Carolina. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to South Carolina. Reviews last updated January 21, 2025.
To help decide which airline to fly from Detroit to South Carolina, see what other customers have to say about Delta, Spirit Airlines and American Airlines. You can also see how each airline compares in terms of entertainment options, comfort, food, crew/service, and boarding process.
Southwest
8.1
Very good
4,662 reviews

Comfort

8.1

Crew

8.7

Food

7.2

Boarding

8.2

Entertainment

7.7

Overall

8.1

Reviews

1 / 10

We BARELY made the connection and when we got onboard we were treated like disobedient children who should have arrived earlier because we had to ask other passengers to move so we could sit with our kids. The flight attendants on the first flight were nice but the second one, they were snippy and fairly rude.

Southwest
8.1
Very good
4,662 reviews
Southwest
8.1
Very good
4,662 reviews

Comfort

8.1

Crew

8.7

Food

7.2

Boarding

8.2

Entertainment

7.7

Overall

8.1

Reviews

1 / 10

We BARELY made the connection and when we got onboard we were treated like disobedient children who should have arrived earlier because we had to ask other passengers to move so we could sit with our kids. The flight attendants on the first flight were nice but the second one, they were snippy and fairly rude.

Alaska Airlines
8.0
Very good
9,706 reviews
Southwest
8.1
Very good
4,662 reviews

Comfort

8.1

Crew

8.7

Food

7.2

Boarding

8.2

Entertainment

7.7

Overall

8.1

Reviews

1 / 10

We BARELY made the connection and when we got onboard we were treated like disobedient children who should have arrived earlier because we had to ask other passengers to move so we could sit with our kids. The flight attendants on the first flight were nice but the second one, they were snippy and fairly rude.

Delta
8.0
Very good
8,521 reviews
Southwest
8.1
Very good
4,662 reviews

Comfort

8.1

Crew

8.7

Food

7.2

Boarding

8.2

Entertainment

7.7

Overall

8.1

Reviews

1 / 10

We BARELY made the connection and when we got onboard we were treated like disobedient children who should have arrived earlier because we had to ask other passengers to move so we could sit with our kids. The flight attendants on the first flight were nice but the second one, they were snippy and fairly rude.

JetBlue
7.4
Good
3,201 reviews
Southwest
8.1
Very good
4,662 reviews

Comfort

8.1

Crew

8.7

Food

7.2

Boarding

8.2

Entertainment

7.7

Overall

8.1

Reviews

1 / 10

We BARELY made the connection and when we got onboard we were treated like disobedient children who should have arrived earlier because we had to ask other passengers to move so we could sit with our kids. The flight attendants on the first flight were nice but the second one, they were snippy and fairly rude.

United Airlines
7.4
Good
8,985 reviews
Southwest
8.1
Very good
4,662 reviews

Comfort

8.1

Crew

8.7

Food

7.2

Boarding

8.2

Entertainment

7.7

Overall

8.1

Reviews

1 / 10

We BARELY made the connection and when we got onboard we were treated like disobedient children who should have arrived earlier because we had to ask other passengers to move so we could sit with our kids. The flight attendants on the first flight were nice but the second one, they were snippy and fairly rude.

Related info for your journey

Find useful and relevant information for your journey from Detroit to South Carolina. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly from for flights from Detroit to South Carolina?

    Most people fly from Detroit All airports (DTT) if they book a flight from Detroit to South Carolina. Detroit All airports is conveniently located just 0.6 mi from Detroit’s city center.

  • What are the cheapest airlines to fly from Detroit to South Carolina one-way?

    $55 is the cheapest one-way deal found within the past few days, from Frontier. You may also be able to find cheap deals on Spirit Airlines and JetBlue, with prices starting from $69 and $117, respectively.

  • What are the most popular routes from Detroit to South Carolina?

    The most popular route from Detroit to South Carolina is Detroit Metropolitan Wayne County - Charleston. You may also consider Detroit Metropolitan Wayne County - Charlotte Douglas or Detroit Metropolitan Wayne County - Myrtle Beach Intl.

  • What are the most reliable airlines from Detroit to South Carolina?

    The top 3 most reliable airlines when flying from Detroit to South Carolina are Endeavor Airlines (90%), WestJet (81%) and Korean Air (79%).

  • What are the cheapest flights from Detroit to South Carolina?

    Looking for the cheapest flight from Detroit to South Carolina? While on average our users pay $353, our data indicates the cheapest price to be $139. The most popular route (Detroit Metropolitan Wayne County - Charleston), is priced around $125.

  • Can I find deals for flights from Detroit to South Carolina that include hotel bookings?

    Yes. In addition to deals on Detroit to South Carolina flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Detroit to South Carolina?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Detroit to South Carolina.

  • Can I find deals for business class flights from Detroit to South Carolina?

    Yes. Cheapflights offers flight deals from Detroit to South Carolina by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Detroit to South Carolina?

    Currently, August is the cheapest month in which you can book a flight from Detroit to South Carolina (average of $217). Flying from Detroit to South Carolina in March is currently the most expensive (average of $335). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Browse thousands of different options on Cheapflights for your next trip

Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.

Alternative routes for Detroit to South Carolina

See prices for flight routes from nearby airports that may be better suited for you.
O'Hare Intl to Las Vegas flights
O'Hare Intl to Orlando flights
O'Hare Intl to Sky Harbor Intl flights
O'Hare Intl to Fort Lauderdale flights
Detroit to Orlando flights
O'Hare Intl to Miami flights
O'Hare Intl to John F Kennedy Intl flights
O'Hare Intl to Dallas/Fort Worth flights
O'Hare Intl to Tampa flights
O'Hare Intl to Denver flights
Detroit to Fort Lauderdale flights
O'Hare Intl to Los Angeles flights
O'Hare Intl to Seattle flights
Detroit to Miami flights
Detroit to Las Vegas flights
O'Hare Intl to LaGuardia flights
Midway to Sky Harbor Intl flights
O'Hare Intl to Boston flights
Midway to Las Vegas flights
Detroit to Sky Harbor Intl flights
O'Hare Intl to San Francisco flights
O'Hare Intl to Newark flights
Midway to Orlando flights
Detroit to Tampa flights
Midway to Dallas/Fort Worth flights
O'Hare Intl to Fort Myers flights
O'Hare Intl to Atlanta flights
Midway to Miami flights
O'Hare Intl to New Orleans flights
O'Hare Intl to Honolulu flights
O'Hare Intl to Austin flights
O'Hare Intl to Salt Lake City flights
O'Hare Intl to San Diego flights
Midway to Newark flights
Detroit to Dallas/Fort Worth flights
Midway to Los Angeles flights
O'Hare Intl to Nashville flights
O'Hare Intl to West Palm Beach flights
Midway to Atlanta flights
Detroit to Denver flights
Detroit to Seattle flights
O'Hare Intl to Santa Ana flights
O'Hare Intl to Baltimore flights
Detroit to New Orleans flights
Detroit to Fort Myers flights
O'Hare Intl to Philadelphia flights
Midway to Hobby flights
Detroit to John F Kennedy Intl flights
Midway to Tampa flights
Detroit to Newark flights

Top 4 airlines flying from Detroit to South Carolina

Discover the top 4 airlines that operate flights from Detroit to South Carolina. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated January 21, 2025.
AirlineCheapestAverageFlexibilityOn-time
Spirit AirlinesCheapest$68Average$163FlexibilityNo cancel feeOn-time65%
DeltaCheapest$139Average$391FlexibilityNo cancel feeOn-timeN/A
SouthwestCheapest$156Average$390FlexibilityNo cancel feeOn-time63%
American AirlinesCheapest$174Average$383FlexibilityNo cancel feeOn-time71%
100% Free
Cheapflights is completely free to use, so you can start saving the moment you arrive.
Book with Flexibility
Our users can plan ahead with confidence and find flights with no change fees
Travel Smart
Millions of people come to us for their flight needs every year. We help make travel planning easy by providing useful insights and data-driven graphs that can inform your decisions.