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$60+ Cheap flights from Des Moines (DSM) to South Carolina

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 2/24. Fares are subject to change and may not be available on all flights or dates of travel.
DSM — CHS
Nov 26 — Dec 31
Tue 11/26
Tue 12/3
1 adult, Economy
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Cheap flight deals from Des Moines to South Carolina

Discover tips and strategies to find the most affordable flight options for your journey from Des Moines (DSM) to South Carolina (USSC). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated November 21, 2024.

Find flight deals from Des Moines to South Carolina

Cheapest flights from Des Moines to South Carolina
Explore the most affordable flight options available from Des Moines to South Carolina. Find the lowest fares from popular airlines and budget airlines, with prices last updated on November 21, 2024.

This Mytrip deal was found by Cheapflights users on 11/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 12/82:37 pmDSM - SAV
1 stop6h 37mAllegiant Air
Sun 12/156:30 amSAV - DSM
1 stop16h 11mAllegiant Air
Deal found 11/19$224
This Delta deal was found by Cheapflights users on 11/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 12/86:34 pmDSM - CAE
1 stop4h 13mDelta
Sun 12/156:00 amCAE - DSM
1 stop5h 33mDelta
Deal found 11/21$253
This Delta deal was found by Cheapflights users on 11/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/2611:19 amDSM - CLT
1 stop4h 10mDelta
Fri 11/295:14 pmCLT - DSM
1 stop4h 48mDelta
Deal found 11/19$302
This American Airlines deal was found by Cheapflights users on 11/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 12/156:27 amDSM - SAV
1 stop4h 56mAmerican Airlines
Sun 12/226:01 pmSAV - DSM
1 stop5h 58mAmerican Airlines
Deal found 11/20$334
This American Airlines deal was found by Cheapflights users on 11/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/235:09 pmDSM - CLT
1 stop13h 46mAmerican Airlines
Sun 11/2411:54 amCLT - DSM
Nonstop2h 46mAmerican Airlines
Deal found 11/19$359
This Delta deal was found by Cheapflights users on 11/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/195:44 amDSM - SAV
1 stop6h 36mDelta
Thu 12/265:40 amSAV - DSM
1 stop6h 20mDelta
Deal found 11/20$361
This Mytrip deal was found by Cheapflights users on 11/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 12/82:20 pmDSM - SAV
2 stops19h 32mMultiple Airlines
Sun 12/156:30 amSAV - DSM
1 stop16h 11mMultiple Airlines
Deal found 11/19$362
This Mytrip deal was found by Cheapflights users on 11/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/52:20 pmDSM - CLT
2 stops22h 42mMultiple Airlines
Sun 12/810:42 pmCLT - DSM
1 stop15h 57mMultiple Airlines
Deal found 11/20$370
This United Airlines deal was found by Cheapflights users on 11/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/2411:29 amDSM - CLT
1 stop4h 54mUnited Airlines
Wed 1/15:25 pmCLT - DSM
1 stop5h 27mUnited Airlines
Deal found 11/21$372
This American Airlines deal was found by Cheapflights users on 11/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/192:02 pmDSM - CHS
1 stop7h 04mAmerican Airlines
Thu 12/266:58 amCHS - DSM
1 stop7h 41mAmerican Airlines
Deal found 11/20$376
This Delta deal was found by Cheapflights users on 11/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/107:39 amDSM - CHS
1 stop8h 36mDelta
Fri 12/136:35 pmCHS - DSM
1 stop5h 14mDelta
Deal found 11/20$391
This American Airlines deal was found by Cheapflights users on 11/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/305:20 amDSM - CAE
2 stops9h 30mAmerican Airlines
Tue 12/34:13 pmCAE - DSM
1 stop7h 36mAmerican Airlines
Deal found 11/21$424

Find flights from Des Moines to South Carolina within your budget

Customize your flight search to find flights from Des Moines to South Carolina that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,612,795 searches. Data last updated November 21, 2024.

Fly from

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Fly to

Any airport

Route

Depart

Return

Price

Des MoinesSavannah

DSM - SAV

DSMSAV

Des Moines

Sun 12/8

2:37 pm-10:14 pm

1 stop6h 37m

Savannah/Hilton Head

Sun 12/15

6:30 am-9:41 pm

1 stop16h 11m

$224

Des MoinesColumbia

DSM - CAE

DSMCAE

Des Moines

Sat 1/4

5:39 pm-11:58 pm

1 stop5h 19m

Columbia Metropolitan

Sat 1/11

7:37 am-12:11 pm

1 stop5h 34m

$249

Des MoinesCharleston

DSM - CHS

DSMCHS

Des Moines

Sat 1/18

10:35 am-5:43 pm

1 stop6h 08m

Charleston

Sat 1/25

6:00 am-11:45 am

1 stop6h 45m

$296

Des MoinesCharleston

DSM - CHS

DSMCHS

Des Moines

Sat 2/22

2:06 pm-10:03 pm

1 stop6h 57m

Charleston

Thu 2/27

6:16 pm-9:57 pm

1 stop4h 41m

$299

Des MoinesGreenville

DSM - GSP

DSMGSP

Des Moines

Thu 1/9

6:17 am-2:05 pm

1 stop6h 48m

Greenville

Sat 1/11

10:29 am-5:21 pm

1 stop7h 52m

$299

Des MoinesCharlotte

DSM - CLT

DSMCLT

Des Moines

Tue 12/24

5:50 am-11:06 am

1 stop4h 16m

Charlotte Douglas

Tue 12/31

6:00 am-12:25 pm

1 stop7h 25m

$302

Des MoinesSavannah

DSM - SAV

DSMSAV

Des Moines

Fri 1/10

6:17 am-1:07 pm

1 stop5h 50m

Savannah/Hilton Head

Mon 1/13

7:46 am-12:11 pm

1 stop5h 25m

$302

Des MoinesCharlotte

DSM - CLT

DSMCLT

Des Moines

Fri 1/10

7:00 am-11:36 pm

1 stop15h 36m

Charlotte Douglas

Wed 1/15

8:55 pm-3:50 pm

2 stops19h 55m

$307

Des MoinesMyrtle Beach

DSM - MYR

DSMMYR

Des Moines

Thu 2/20

2:06 pm-10:29 pm

1 stop7h 23m

Myrtle Beach Intl

Thu 2/27

6:27 pm-9:57 pm

1 stop4h 30m

$329

Des MoinesMyrtle Beach

DSM - MYR

DSMMYR

Des Moines

Sat 1/4

7:20 am-4:56 pm

1 stop8h 36m

Myrtle Beach Intl

Sat 1/11

12:56 pm-5:15 pm

1 stop5h 19m

$331

Flights are sorted by cheapest round-trip flights first.

Deals found on 11/21

Showing 1-10 of 54 results
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Best time to book a flight from Des Moines to South Carolina

Have a flexible travel schedule? Discover the best time to fly to South Carolina from Des Moines with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Travel insights for flights from Des Moines to South Carolina

Get recent, data-driven insights about flights from Des Moines to South Carolina including ideal travel times, pricing trends, and more.

What is the cheapest month to book a flight from Des Moines to South Carolina?

Currently, August is the cheapest month in which you can book a flight from Des Moines to South Carolina (average of $217). Flying from Des Moines to South Carolina in April is currently the most expensive (average of $314). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from DSM to SC?

Find hourly flight availability from Des Moines to South Carolina. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated November 21, 2024.

Regardless of the time of day you decide to fly, the ticket price will remain around the same. Book flights from Des Moines to South Carolina as you normally would.

Rainfall in South Carolina by month

Plan your trip to South Carolina by taking into account the average rainfall totals by month.

In terms of precipitation, rainfall in South Carolina ranges from 3.0 - 6.5 inches per month. July is typically the wettest month, when rainfall can reach 6.5 in. November is typically the driest time to visit South Carolina when rainfall is around 3.0 in.

Temperature in South Carolina by month

Plan your trip to South Carolina by taking into account the average temperature totals by month.

If weather is an important factor for your trip to South Carolina, use this chart to help with planning. For those seeking warmer temperatures, July is the ideal time of year to visit, when temperatures reach an average of 78.8 F. Travelers looking to avoid the cold should look outside of January, when temperatures are typically at their lowest (around 44.6 F).

Reviews of airlines servicing South Carolina

Get insights into the airlines that provide service to South Carolina. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to South Carolina. Reviews last updated November 21, 2024.
Get a feel of what it's like to fly with Delta, United Airlines and Southwest from Des Moines to South Carolina by reading reviews from past customers. You can also see how each airline compares in terms of entertainment options, comfort, food, crew/service, and boarding process.
Southwest
8.1
Very good
5,005 reviews

Food

7.2

Comfort

8.1

Entertainment

7.7

Crew

8.7

Boarding

8.2

Overall

8.1

Reviews

1 / 10

Great service throughout our flight. Easy boarding with early bird check in

Southwest
8.1
Very good
5,005 reviews
Southwest
8.1
Very good
5,005 reviews

Food

7.2

Comfort

8.1

Entertainment

7.7

Crew

8.7

Boarding

8.2

Overall

8.1

Reviews

1 / 10

Great service throughout our flight. Easy boarding with early bird check in

Delta
8.0
Very good
8,755 reviews
Southwest
8.1
Very good
5,005 reviews

Food

7.2

Comfort

8.1

Entertainment

7.7

Crew

8.7

Boarding

8.2

Overall

8.1

Reviews

1 / 10

Great service throughout our flight. Easy boarding with early bird check in

United Airlines
7.4
Good
9,172 reviews
Southwest
8.1
Very good
5,005 reviews

Food

7.2

Comfort

8.1

Entertainment

7.7

Crew

8.7

Boarding

8.2

Overall

8.1

Reviews

1 / 10

Great service throughout our flight. Easy boarding with early bird check in

Allegiant Air
7.4
Good
850 reviews
Southwest
8.1
Very good
5,005 reviews

Food

7.2

Comfort

8.1

Entertainment

7.7

Crew

8.7

Boarding

8.2

Overall

8.1

Reviews

1 / 10

Great service throughout our flight. Easy boarding with early bird check in

WestJet
7.3
Good
2,811 reviews
Southwest
8.1
Very good
5,005 reviews

Food

7.2

Comfort

8.1

Entertainment

7.7

Crew

8.7

Boarding

8.2

Overall

8.1

Reviews

1 / 10

Great service throughout our flight. Easy boarding with early bird check in

Related info for your journey

Find useful and relevant information for your journey from Des Moines to South Carolina. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly from for flights from Des Moines to South Carolina?

    Des Moines (DSM), located 3.6 mi from the city center, is the airport you fly out of when you book flights from Des Moines to South Carolina.

  • What are the cheapest airlines to fly from Des Moines to South Carolina one-way?

    For one-way options, check prices for Frontier. According to our data, you can fly for as low as $60. Users have also found prices from $142 and $148 on American Airlines and Delta, respectively.

  • What are the most popular routes from Des Moines to South Carolina?

    When deciding which route to take from Des Moines to South Carolina consider Des Moines - Charlotte Douglas, Des Moines - Charleston or Des Moines - Savannah/Hilton Head as they are the most popular.

  • Can I find deals for flights from Des Moines to South Carolina that include hotel bookings?

    Yes. In addition to deals on Des Moines to South Carolina flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Des Moines to South Carolina?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Des Moines to South Carolina.

  • Can I find deals for business class flights from Des Moines to South Carolina?

    Yes. Cheapflights offers flight deals from Des Moines to South Carolina by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Des Moines to South Carolina?

    Currently, August is the cheapest month in which you can book a flight from Des Moines to South Carolina (average of $217). Flying from Des Moines to South Carolina in April is currently the most expensive (average of $314). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

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Alternative routes for Des Moines to South Carolina

See prices for flight routes from nearby airports that may be better suited for you.
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Top 3 airlines flying from Des Moines to South Carolina

Discover the top 3 airlines that operate flights from Des Moines to South Carolina. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,612,795 searches. Data last updated November 21, 2024.
AirlineCheapestAverageFlexibilityOn-time
DeltaCheapest$215Average$383FlexibilityNo cancel feeOn-timeN/A
American AirlinesCheapest$225Average$401FlexibilityNo cancel feeOn-time71%
United AirlinesCheapest$247Average$423FlexibilityNo cancel feeOn-time69%
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