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South Carolina

$81+ Cheap flights from Colorado to South Carolina

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 3/8. Fares are subject to change and may not be available on all flights or dates of travel.
DEN — CHS
Feb 25 — Mar 41
Tue 2/25
Tue 3/4
1 adult, Economy
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Cheap flight deals from Colorado to South Carolina

Keep the following information in mind while searching for Colorado to South Carolina flight deals. Data was last updated February 20, 2025.

Most accurate provider

FlightHub
3 stars

Most trusted provider

FlightHub
3 stars

Round-trip from

$105
(Gotogate)

One-way from

$81
(Frontier)

Popular in

December

Cheapest in

September

Average price

$487

Good round-trip deal

$416 or less

Good one-way deal

$249 or less
Provider with most accurate pricing for Denver Intl-Myrtle Beach Intl flight deals.
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Provider most trusted by Cheapflights users for Denver Intl-Myrtle Beach Intl flights.
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From Colorado to South Carolina
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One-way flight from Colorado to South Carolina
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Highest demand for flights based on searches. 6% potential increase in price ($33 potential increase over avg. RT price).
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Cheapest flight prices on average. 2% potential price decrease ($9 potential savings vs. average RT price).
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Average for round-trip flights in February 2025
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Price to beat on a round-trip flight from Colorado to South Carolina.
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Price to beat on a one-way flight from Colorado to South Carolina.
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Find flight deals from Colorado to South Carolina

Cheapest flights from Colorado to South Carolina
Explore the most affordable flight options available from Colorado to South Carolina. Find the lowest fares from popular airlines and budget airlines, with prices last updated on February 20, 2025.

This Gotogate deal was found by Cheapflights users on 2/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Gotogate is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 4/51:41 pmDEN - CLT
Nonstop3h 16mFrontier
Sun 4/610:20 pmCLT - DEN
Nonstop4h 01mFrontier
Deal found 2/20$105
This American Airlines deal was found by Cheapflights users on 2/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 4/110:20 amDEN - CLT
Nonstop3h 22mAmerican Airlines
Wed 4/95:37 pmCLT - DEN
Nonstop3h 40mAmerican Airlines
Deal found 2/20$217
This Mytrip deal was found by Cheapflights users on 2/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 3/277:00 pmDEN - CLT
1 stop15h 00mMultiple Airlines
Sat 3/297:54 pmCLT - DEN
Nonstop3h 55mMultiple Airlines
Deal found 2/20$224
This Delta deal was found by Cheapflights users on 2/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 4/112:20 pmDEN - CLT
1 stop7h 40mDelta
Wed 4/95:21 pmCLT - DEN
1 stop7h 41mDelta
Deal found 2/20$237
This Sun Country Air deal was found by Cheapflights users on 2/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Sun Country Air is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 3/277:00 pmDEN - CLT
1 stop15h 00mSun Country Air
Sun 3/307:00 amCLT - DEN
1 stop27h 15mSun Country Air
Deal found 2/20$260
This Southwest deal was found by Cheapflights users on 2/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 3/1212:25 pmDEN - CLT
1 stop7h 25mSouthwest
Wed 3/1912:05 pmCLT - DEN
Nonstop3h 50mSouthwest
Deal found 2/20$267
This American Airlines deal was found by Cheapflights users on 2/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/106:00 amCOS - SAV
1 stop7h 07mAmerican Airlines
Tue 5/137:40 pmSAV - COS
1 stop6h 06mAmerican Airlines
Deal found 2/20$269
This Delta deal was found by Cheapflights users on 2/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 4/112:55 amDEN - GSP
1 stop6h 32mDelta
Wed 4/95:46 amGSP - DEN
1 stop7h 22mDelta
Deal found 2/20$269
This American Airlines deal was found by Cheapflights users on 2/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/911:59 pmDEN - CAE
1 stop6h 22mAmerican Airlines
Tue 4/154:51 pmCAE - DEN
1 stop7h 07mAmerican Airlines
Deal found 2/20$269
This American Airlines deal was found by Cheapflights users on 2/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/108:06 amDEN - HHH
1 stop7h 44mAmerican Airlines
Fri 5/166:20 pmHHH - DEN
1 stop6h 40mAmerican Airlines
Deal found 2/20$269
This Delta deal was found by Cheapflights users on 2/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 4/266:00 amCOS - GSP
1 stop6h 14mDelta
Fri 5/95:05 pmGSP - COS
1 stop6h 15mDelta
Deal found 2/20$269
This Southwest deal was found by Cheapflights users on 2/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 3/59:15 amDEN - GSP
1 stop4h 20mSouthwest
Wed 3/127:50 amGSP - DEN
1 stop10h 50mSouthwest
Deal found 2/19$274

Find flights from Colorado to South Carolina within your budget

Customize your flight search to find flights from Colorado to South Carolina that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated February 20, 2025.

Fly from

Colorado

Fly to

South Carolina

Route

Depart

Return

Price

DenverCharlotte

DEN - CLT

DENCLT

Denver Intl

Sat 4/5

1:41 pm-6:57 pm

Nonstop3h 16m

Charlotte Douglas

Sun 4/6

10:20 pm-12:21 am

Nonstop4h 01m

$105

DenverCharlotte

DEN - CLT

DENCLT

Denver Intl

Tue 4/1

10:20 am-3:42 pm

Nonstop3h 22m

Charlotte Douglas

Wed 4/9

5:37 pm-7:17 pm

Nonstop3h 40m

$217

DenverCharlotte

DEN - CLT

DENCLT

Denver Intl

Thu 3/27

7:00 pm-12:00 pm

1 stop15h 00m

Charlotte Douglas

Sat 3/29

7:54 pm-9:49 pm

Nonstop3h 55m

$224

DenverCharlotte

DEN - CLT

DENCLT

Denver Intl

Tue 4/1

10:35 am-6:09 pm

1 stop5h 34m

Charlotte Douglas

Tue 4/8

9:40 am-1:53 pm

1 stop6h 13m

$237

DenverCharlotte

DEN - CLT

DENCLT

Denver Intl

Thu 3/27

7:00 pm-12:00 pm

1 stop15h 00m

Charlotte Douglas

Sun 3/30

7:00 am-8:15 am

1 stop27h 15m

$260

DenverCharlotte

DEN - CLT

DENCLT

Denver Intl

Wed 3/12

12:25 pm-9:50 pm

1 stop7h 25m

Charlotte Douglas

Wed 3/19

12:05 pm-1:55 pm

Nonstop3h 50m

$267

Colorado SpringsSavannah

COS - SAV

COSSAV

Colorado Springs

Sat 5/10

6:00 am-3:07 pm

1 stop7h 07m

Savannah/Hilton Head

Tue 5/13

7:40 pm-11:46 pm

1 stop6h 06m

$269

DenverGreenville

DEN - GSP

DENGSP

Denver Intl

Tue 4/1

12:55 am-9:27 am

1 stop6h 32m

Greenville

Wed 4/9

5:46 am-11:08 am

1 stop7h 22m

$269

DenverColumbia

DEN - CAE

DENCAE

Denver Intl

Wed 4/9

11:59 pm-8:21 am

1 stop6h 22m

Columbia Metropolitan

Tue 4/15

4:51 pm-9:58 pm

1 stop7h 07m

$269

Colorado SpringsGreenville

COS - GSP

COSGSP

Colorado Springs

Sat 4/26

6:00 am-2:14 pm

1 stop6h 14m

Greenville

Fri 5/9

5:05 pm-9:20 pm

1 stop6h 15m

$269

Flights are sorted by cheapest round-trip flights first.

Deals found on 2/20

Showing 1-10 of 60 results
1
2
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6

Best time to book a flight from Colorado to South Carolina

Have a flexible travel schedule? Discover the best time to fly to South Carolina from Colorado with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Travel insights for flights from Colorado to South Carolina

Get recent, data-driven insights about flights from Colorado to South Carolina including ideal travel times, pricing trends, and more.

What is the cheapest month to book a flight from Colorado to South Carolina?

Currently, August is the cheapest month in which you can book a flight from Colorado to South Carolina (average of $217). Flying from Colorado to South Carolina in March is currently the most expensive (average of $335). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from CO to SC?

Find hourly flight availability from Colorado to South Carolina. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated February 20, 2025.

Regardless of the time of day you decide to fly, the ticket price will remain around the same. Book flights from Colorado to South Carolina as you normally would.

Weekly flight availability from Colorado to South Carolina

Explore weekly flight availability from Colorado to South Carolina. Discover flights operating on different days of the week, giving you the flexibility to choose a travel day that best fits your plans. Compare info to find the most convenient option for your journey. Data last updated February 20, 2025.

The most flights from USCO to USSC are scheduled on a Tuesday (2 on average). You will have fewer flight options on Monday, which is when the least amount of flights are scheduled (1 on average).

Rainfall in South Carolina by month

Plan your trip to South Carolina by taking into account the average rainfall totals by month.

In terms of precipitation, rainfall in South Carolina ranges from 3.0 - 6.5 inches per month. July is typically the wettest month, when rainfall can reach 6.5 in. November is typically the driest time to visit South Carolina when rainfall is around 3.0 in.

Temperature in South Carolina by month

Plan your trip to South Carolina by taking into account the average temperature totals by month.

If weather is an important factor for your trip to South Carolina, use this chart to help with planning. For those seeking warmer temperatures, July is the ideal time of year to visit, when temperatures reach an average of 78.8 F. Travelers looking to avoid the cold should look outside of January, when temperatures are typically at their lowest (around 44.6 F).

Reviews of airlines servicing South Carolina

Get insights into the airlines that provide service to South Carolina. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to South Carolina. Reviews last updated February 20, 2025.
To help decide which airline to fly from Colorado to South Carolina, see what other customers have to say about Southwest, Breeze Airways and Alaska Airlines. You can also see how each airline stacks up in terms of entertainment options, comfort, food, crew/service, and boarding process.
Southwest
8.1
Very good
4,411 reviews

Crew

8.7

Overall

8.1

Boarding

8.2

Entertainment

7.6

Food

7.1

Comfort

8.1

Reviews

1 / 20

2.0
Mediocre

Anonymous,Feb 2025

MCO - STL

Cancelled at last minute, SWA unable to assist in formulating alternate plans. Wound up renting a car and driving 13 hours to beat bad weather forecast at home. Not SWA’s fault that there was significant bad weather across the country.

Southwest
8.1
Very good
4,411 reviews
Southwest
8.1
Very good
4,411 reviews

Crew

8.7

Overall

8.1

Boarding

8.2

Entertainment

7.6

Food

7.1

Comfort

8.1

Reviews

1 / 20

2.0
Mediocre

Anonymous,Feb 2025

MCO - STL

Cancelled at last minute, SWA unable to assist in formulating alternate plans. Wound up renting a car and driving 13 hours to beat bad weather forecast at home. Not SWA’s fault that there was significant bad weather across the country.

Breeze Airways
8.1
Very good
150 reviews
Southwest
8.1
Very good
4,411 reviews

Crew

8.7

Overall

8.1

Boarding

8.2

Entertainment

7.6

Food

7.1

Comfort

8.1

Reviews

1 / 20

2.0
Mediocre

Anonymous,Feb 2025

MCO - STL

Cancelled at last minute, SWA unable to assist in formulating alternate plans. Wound up renting a car and driving 13 hours to beat bad weather forecast at home. Not SWA’s fault that there was significant bad weather across the country.

Alaska Airlines
8.0
Very good
9,697 reviews
Southwest
8.1
Very good
4,411 reviews

Crew

8.7

Overall

8.1

Boarding

8.2

Entertainment

7.6

Food

7.1

Comfort

8.1

Reviews

1 / 20

2.0
Mediocre

Anonymous,Feb 2025

MCO - STL

Cancelled at last minute, SWA unable to assist in formulating alternate plans. Wound up renting a car and driving 13 hours to beat bad weather forecast at home. Not SWA’s fault that there was significant bad weather across the country.

Delta
8.0
Very good
8,219 reviews
Southwest
8.1
Very good
4,411 reviews

Crew

8.7

Overall

8.1

Boarding

8.2

Entertainment

7.6

Food

7.1

Comfort

8.1

Reviews

1 / 20

2.0
Mediocre

Anonymous,Feb 2025

MCO - STL

Cancelled at last minute, SWA unable to assist in formulating alternate plans. Wound up renting a car and driving 13 hours to beat bad weather forecast at home. Not SWA’s fault that there was significant bad weather across the country.

JetBlue
7.4
Good
3,070 reviews
Southwest
8.1
Very good
4,411 reviews

Crew

8.7

Overall

8.1

Boarding

8.2

Entertainment

7.6

Food

7.1

Comfort

8.1

Reviews

1 / 20

2.0
Mediocre

Anonymous,Feb 2025

MCO - STL

Cancelled at last minute, SWA unable to assist in formulating alternate plans. Wound up renting a car and driving 13 hours to beat bad weather forecast at home. Not SWA’s fault that there was significant bad weather across the country.

Related info for your journey

Find useful and relevant information for your journey from Colorado to South Carolina. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How popular is this Colorado to South Carolina flight route?

    Within the past month, 1 users have taken a look at flights from Colorado to South Carolina.

  • What are the cheapest airlines to fly from Colorado to South Carolina one-way?

    The cheapest airline one-way is Frontier, with whom users have recently found tickets for as low as $81. However, be on the lookout for offers from American Airlines and Sun Country Air, as they are both options that can get you from Colorado to South Carolina for a low price.

  • Can I find deals for flights from Colorado to South Carolina that include hotel bookings?

    Yes. In addition to deals on Colorado to South Carolina flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Colorado to South Carolina?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Colorado to South Carolina.

  • Can I find deals for business class flights from Colorado to South Carolina?

    Yes. Cheapflights offers flight deals from Colorado to South Carolina by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Colorado to South Carolina?

    Currently, August is the cheapest month in which you can book a flight from Colorado to South Carolina (average of $217). Flying from Colorado to South Carolina in March is currently the most expensive (average of $335). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

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Alternative routes for Colorado to South Carolina

See prices for flight routes from nearby airports that may be better suited for you.
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Top 5 airlines flying from Colorado to South Carolina

Discover the top 5 airlines that operate flights from Colorado to South Carolina. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated February 20, 2025.
AirlineCheapestAverageFlexibilityOn-time
FrontierCheapest$138Average$274FlexibilityNo cancel feeOn-time62%
American AirlinesCheapest$197Average$481FlexibilityNo cancel feeOn-time71%
DeltaCheapest$216Average$417FlexibilityNo cancel feeOn-timeN/A
United AirlinesCheapest$246Average$559FlexibilityNo cancel feeOn-time69%
SouthwestCheapest$273Average$513FlexibilityNo cancel feeOn-time63%
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