South Carolina

$98+ Cheap flights from Colorado to South Carolina

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 6/7. Fares are subject to change and may not be available on all flights or dates of travel.
DEN — CHS
Apr 7 — Apr 141
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Cheap flight deals from Colorado to South Carolina

Keep the following information in mind while searching for Colorado to South Carolina flight deals. Data was last updated April 2, 2025.

Most accurate provider

FlightHub
3 stars

Most trusted provider

FlightHub
3 stars

Round-trip from

$135
(CheapOair)

One-way from

$99
(American Airlines)

Popular in

December

Cheapest in

May

Average price

$404

Good round-trip deal

$389 or less

Good one-way deal

$208 or less
Provider with most accurate pricing for Denver Intl-Myrtle Beach Intl flight deals.
Provider most trusted by Cheapflights users for Denver Intl-Myrtle Beach Intl flights.
From Colorado to South Carolina
One-way flight from Colorado to South Carolina
Highest demand for flights based on searches. 9% potential increase in price ($44 potential increase over avg. RT price).
Cheapest flight prices on average. 2% potential price decrease ($11 potential savings vs. average RT price).
Average for round-trip flights in April 2025
Price to beat on a round-trip flight from Colorado to South Carolina.
Price to beat on a one-way flight from Colorado to South Carolina.

Find flight deals from Colorado to South Carolina

Cheapest flights from Colorado to South Carolina
Explore the most affordable flight options available from Colorado to South Carolina. Find the lowest fares from popular airlines and budget airlines, with prices last updated on April 2, 2025.

This Cheapflightsfares deal was found by Cheapflights users on 4/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/110:45 amDEN - CLT
Nonstop3h 20mFrontier
Thu 5/85:06 pmCLT - DEN
Nonstop3h 58mFrontier
Deal found 4/1$136
This Mytrip deal was found by Cheapflights users on 4/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/16:30 pmDEN - CLT
1 stop15h 42mMultiple Airlines
Thu 5/85:06 pmCLT - DEN
Nonstop3h 58mMultiple Airlines
Deal found 4/1$155
This American Airlines deal was found by Cheapflights users on 3/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/308:06 amDEN - CLT
Nonstop3h 22mAmerican Airlines
Wed 5/77:45 amCLT - DEN
Nonstop3h 36mAmerican Airlines
Deal found 3/31$179
This United Airlines deal was found by Cheapflights users on 4/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 4/295:22 pmDEN - CLT
Nonstop3h 17mUnited Airlines
Tue 5/68:15 amCLT - DEN
Nonstop3h 50mUnited Airlines
Deal found 4/1$188
This Southwest deal was found by Cheapflights users on 4/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/36:05 pmDEN - CLT
Nonstop3h 20mSouthwest
Tue 5/61:55 pmCLT - DEN
2 stops8h 00mSouthwest
Deal found 4/1$203
This American Airlines deal was found by Cheapflights users on 4/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/76:15 amDEN - AGS
1 stop5h 52mAmerican Airlines
Wed 5/146:30 pmAGS - DEN
1 stop6h 29mAmerican Airlines
Deal found 4/1$217
This Sun Country Air deal was found by Cheapflights users on 4/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Sun Country Air is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/86:30 pmDEN - CLT
1 stop21h 12mSun Country Air
Mon 5/126:40 pmCLT - DEN
1 stop18h 50mSun Country Air
Deal found 4/1$225
This Delta deal was found by Cheapflights users on 4/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 4/226:00 amDEN - CLT
1 stop6h 54mDelta
Sat 4/266:00 amCLT - DEN
1 stop5h 25mDelta
Deal found 4/1$237
This American Airlines deal was found by Cheapflights users on 4/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/216:00 amCOS - CHS
1 stop6h 52mAmerican Airlines
Tue 6/37:14 pmCHS - COS
1 stop6h 31mAmerican Airlines
Deal found 4/1$251
This United Airlines deal was found by Cheapflights users on 4/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/1911:59 pmDEN - GSP
1 stop7h 50mUnited Airlines
Tue 9/234:30 pmGSP - DEN
Nonstop3h 27mUnited Airlines
Deal found 4/1$259
This United Airlines deal was found by Cheapflights users on 4/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 7/46:00 amDEN - MYR
1 stop6h 35mUnited Airlines
Tue 7/85:12 pmMYR - DEN
1 stop8h 08mUnited Airlines
Deal found 4/1$264
This American Airlines deal was found by Cheapflights users on 4/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 4/226:30 amDEN - GSP
1 stop5h 33mAmerican Airlines
Sat 4/269:01 amGSP - DEN
1 stop6h 27mAmerican Airlines
Deal found 4/1$268

Cheapflights Fare Finder

Customize your flight search to find flights from Colorado to South Carolina that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated April 2, 2025.
Use the filters below to find and compare flights from Colorado to South Carolina that are best for you.

Fly from

Colorado

Fly to

South Carolina

Route

Depart

Return

Price

DenverCharlotte

DEN - CLT

DENCLT

Denver Intl

Thu 5/1

10:45 am-4:05 pm

Nonstop3h 20m

Charlotte Douglas

Thu 5/8

5:06 pm-7:04 pm

Nonstop3h 58m

$136

DenverCharlotte

DEN - CLT

DENCLT

Denver Intl

Thu 5/1

6:30 pm-12:12 pm

1 stop15h 42m

Charlotte Douglas

Thu 5/8

5:06 pm-7:04 pm

Nonstop3h 58m

$155

DenverCharlotte

DEN - CLT

DENCLT

Denver Intl

Wed 4/30

8:06 am-1:28 pm

Nonstop3h 22m

Charlotte Douglas

Wed 5/7

7:45 am-9:21 am

Nonstop3h 36m

$179

DenverCharlotte

DEN - CLT

DENCLT

Denver Intl

Tue 4/29

5:22 pm-10:39 pm

Nonstop3h 17m

Charlotte Douglas

Tue 5/6

8:15 am-10:05 am

Nonstop3h 50m

$188

DenverCharlotte

DEN - CLT

DENCLT

Denver Intl

Sat 5/3

6:05 pm-11:25 pm

Nonstop3h 20m

Charlotte Douglas

Tue 5/6

1:55 pm-7:55 pm

2 stops8h 00m

$203

DenverAugusta

DEN - AGS

DENAGS

Denver Intl

Wed 5/7

6:15 am-2:07 pm

1 stop5h 52m

Augusta Bush Field

Wed 5/14

6:30 pm-10:59 pm

1 stop6h 29m

$217

DenverCharlotte

DEN - CLT

DENCLT

Denver Intl

Thu 5/8

6:30 pm-5:42 pm

1 stop21h 12m

Charlotte Douglas

Mon 5/12

6:40 pm-11:30 am

1 stop18h 50m

$225

DenverCharlotte

DEN - CLT

DENCLT

Denver Intl

Tue 4/22

6:00 am-2:54 pm

1 stop6h 54m

Charlotte Douglas

Sat 4/26

6:00 am-9:25 am

1 stop5h 25m

$237

Colorado SpringsCharleston

COS - CHS

COSCHS

Colorado Springs

Wed 5/21

6:00 am-2:52 pm

1 stop6h 52m

Charleston

Tue 6/3

7:14 pm-11:45 pm

1 stop6h 31m

$251

DenverGreenville

DEN - GSP

DENGSP

Denver Intl

Fri 9/19

11:59 pm-9:49 am

1 stop7h 50m

Greenville

Tue 9/23

4:30 pm-5:57 pm

Nonstop3h 27m

$259

Flights are sorted by cheapest round-trip flights first.

Deals found on 4/1

Showing 1-10 of 60 results
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Best time to book a flight from Colorado to South Carolina

Have a flexible travel schedule? Discover the best time to fly to South Carolina from Colorado with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Colorado to South Carolina

What is the cheapest month to book a flight from Colorado to South Carolina?

Currently, August is the cheapest month in which you can book a flight from Colorado to South Carolina (average of $217). Flying from Colorado to South Carolina in March is currently the most expensive (average of $335). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from CO to SC?

Find hourly flight availability from Colorado to South Carolina. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated April 2, 2025.

Regardless of the time of day you decide to fly, the ticket price will remain around the same. Book flights from Colorado to South Carolina as you normally would.

Rainfall in South Carolina by month

Plan your trip to South Carolina by taking into account the average rainfall totals by month.

In terms of precipitation, rainfall in South Carolina ranges from 3.0 - 6.5 inches per month. July is typically the wettest month, when rainfall can reach 6.5 in. November is typically the driest time to visit South Carolina when rainfall is around 3.0 in.

Temperature in South Carolina by month

Plan your trip to South Carolina by taking into account the average temperature totals by month.

If weather is an important factor for your trip to South Carolina, use this chart to help with planning. For those seeking warmer temperatures, July is the ideal time of year to visit, when temperatures reach an average of 78.8 F. Travelers looking to avoid the cold should look outside of January, when temperatures are typically at their lowest (around 44.6 F).

Reviews of airlines servicing South Carolina

Get insights into the airlines that provide service to South Carolina. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to South Carolina. Reviews last updated April 2, 2025.
To help decide which airline to fly from Colorado to South Carolina, see what other customers have to say about Breeze Airways, Alaska Airlines and Southwest. You can also see how each airline stacks up in terms of entertainment options, comfort, food, crew/service, and boarding process.

Crew

8.8

Comfort

8.2

Overall

8.1

Boarding

8.3

Food

6.7

Entertainment

6.6

Reviews

1 / 11
10.0
Excellent

Dena,Dec 2024

LAS - BDL

It was comfortable and the crew was great! A few free snacks offered would be nice!

Crew

8.8

Comfort

8.2

Overall

8.1

Boarding

8.3

Food

6.7

Entertainment

6.6

Reviews

1 / 11
10.0
Excellent

Dena,Dec 2024

LAS - BDL

It was comfortable and the crew was great! A few free snacks offered would be nice!

Crew

8.8

Comfort

8.2

Overall

8.1

Boarding

8.3

Food

6.7

Entertainment

6.6

Reviews

1 / 11
10.0
Excellent

Dena,Dec 2024

LAS - BDL

It was comfortable and the crew was great! A few free snacks offered would be nice!

Crew

8.8

Comfort

8.2

Overall

8.1

Boarding

8.3

Food

6.7

Entertainment

6.6

Reviews

1 / 11
10.0
Excellent

Dena,Dec 2024

LAS - BDL

It was comfortable and the crew was great! A few free snacks offered would be nice!
8.0
Very good

Crew

8.8

Comfort

8.2

Overall

8.1

Boarding

8.3

Food

6.7

Entertainment

6.6

Reviews

1 / 11
10.0
Excellent

Dena,Dec 2024

LAS - BDL

It was comfortable and the crew was great! A few free snacks offered would be nice!

Crew

8.8

Comfort

8.2

Overall

8.1

Boarding

8.3

Food

6.7

Entertainment

6.6

Reviews

1 / 11
10.0
Excellent

Dena,Dec 2024

LAS - BDL

It was comfortable and the crew was great! A few free snacks offered would be nice!

Related info for your journey

Find useful and relevant information for your journey from Colorado to South Carolina. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
  • How popular is this Colorado to South Carolina flight route?

  • What are the cheapest airlines to fly from Colorado to South Carolina one-way?

    The cheapest airline one-way is American Airlines, with whom users have recently found tickets for as low as $99. However, be on the lookout for offers from Frontier and United Airlines, as they are both options that can get you from Colorado to South Carolina for a low price.

  • Can I find deals for flights from Colorado to South Carolina that include hotel bookings?

    Yes. In addition to deals on Colorado to South Carolina flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Colorado to South Carolina?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Colorado to South Carolina.

  • Can I find deals for business class flights from Colorado to South Carolina?

    Yes. Cheapflights offers flight deals from Colorado to South Carolina by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Colorado to South Carolina?

    Currently, August is the cheapest month in which you can book a flight from Colorado to South Carolina (average of $217). Flying from Colorado to South Carolina in March is currently the most expensive (average of $335). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Browse thousands of different options on Cheapflights for your next trip

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Alternative routes for Colorado to South Carolina

See prices for flight routes from nearby airports that may be better suited for you.

Top 6 airlines flying from Colorado to South Carolina

Discover the top 6 airlines that operate flights from Colorado to South Carolina. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated April 2, 2025.
AirlineCheapestAverageFlexibilityOn-time
FrontierCheapest$136Average$248FlexibilityNo cancel feeOn-time62%
DeltaCheapest$169Average$388FlexibilityNo cancel feeOn-timeN/A
Sun Country AirCheapest$173Average$299FlexibilityNo cancel feeOn-time83%
American AirlinesCheapest$198Average$501FlexibilityNo cancel feeOn-time71%
United AirlinesCheapest$246Average$528FlexibilityNo cancel feeOn-time69%
SouthwestCheapest$273Average$515FlexibilityNo cancel feeOn-time63%

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